ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KODCOHLO_00001 1.35e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KODCOHLO_00002 3.72e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KODCOHLO_00003 1.78e-316 yhdG - - E ko:K03294 - ko00000 amino acid
KODCOHLO_00004 2.8e-265 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KODCOHLO_00005 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
KODCOHLO_00006 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
KODCOHLO_00007 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KODCOHLO_00008 8.84e-140 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KODCOHLO_00009 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KODCOHLO_00010 1.97e-92 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
KODCOHLO_00011 5.75e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KODCOHLO_00012 2.61e-299 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KODCOHLO_00013 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
KODCOHLO_00014 2.48e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KODCOHLO_00015 4.54e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KODCOHLO_00016 7.09e-163 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KODCOHLO_00017 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
KODCOHLO_00018 1.91e-261 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
KODCOHLO_00019 1.19e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KODCOHLO_00020 5.47e-198 nodB1 - - G - - - deacetylase
KODCOHLO_00021 5.67e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KODCOHLO_00022 1e-113 pksA - - K - - - Transcriptional regulator
KODCOHLO_00023 1.55e-123 ymcC - - S - - - Membrane
KODCOHLO_00024 7.15e-110 - - - T - - - universal stress protein
KODCOHLO_00026 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KODCOHLO_00027 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KODCOHLO_00028 1.11e-141 yheG - - GM - - - NAD(P)H-binding
KODCOHLO_00030 3.3e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
KODCOHLO_00031 4.28e-49 yheE - - S - - - Family of unknown function (DUF5342)
KODCOHLO_00032 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
KODCOHLO_00033 4.41e-272 yheC - - HJ - - - YheC/D like ATP-grasp
KODCOHLO_00034 3.19e-263 yheB - - S - - - Belongs to the UPF0754 family
KODCOHLO_00035 3.3e-70 yheA - - S - - - Belongs to the UPF0342 family
KODCOHLO_00036 3.77e-253 yhaZ - - L - - - DNA alkylation repair enzyme
KODCOHLO_00037 3.44e-204 yhaX - - S - - - haloacid dehalogenase-like hydrolase
KODCOHLO_00038 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
KODCOHLO_00039 2.89e-316 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
KODCOHLO_00040 4.03e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
KODCOHLO_00041 8.88e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
KODCOHLO_00043 4.11e-175 yhaR - - I - - - enoyl-CoA hydratase
KODCOHLO_00044 7.01e-20 - - - S - - - YhzD-like protein
KODCOHLO_00045 5.34e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_00046 2.39e-277 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
KODCOHLO_00047 1.02e-297 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
KODCOHLO_00048 0.0 yhaN - - L - - - AAA domain
KODCOHLO_00049 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
KODCOHLO_00050 2.87e-43 yhaL - - S - - - Sporulation protein YhaL
KODCOHLO_00051 1.53e-184 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KODCOHLO_00052 1.29e-123 yhaK - - S - - - Putative zincin peptidase
KODCOHLO_00053 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
KODCOHLO_00054 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
KODCOHLO_00055 4.74e-55 yhaH - - S - - - YtxH-like protein
KODCOHLO_00056 2.55e-24 - - - - - - - -
KODCOHLO_00057 3.36e-99 trpP - - S - - - Tryptophan transporter TrpP
KODCOHLO_00058 4.86e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KODCOHLO_00059 3.37e-104 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KODCOHLO_00060 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
KODCOHLO_00061 1.29e-280 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KODCOHLO_00062 3.38e-159 ecsC - - S - - - EcsC protein family
KODCOHLO_00063 9.88e-283 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KODCOHLO_00064 4.85e-312 yhfA - - C - - - membrane
KODCOHLO_00065 3.1e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
KODCOHLO_00066 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KODCOHLO_00067 2.99e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KODCOHLO_00068 4.49e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KODCOHLO_00069 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KODCOHLO_00070 3.1e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_00071 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
KODCOHLO_00072 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KODCOHLO_00074 7.37e-251 yhfE - - G - - - peptidase M42
KODCOHLO_00075 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KODCOHLO_00076 5.69e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KODCOHLO_00077 1.85e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KODCOHLO_00078 5.81e-139 yhfK - - GM - - - NmrA-like family
KODCOHLO_00079 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KODCOHLO_00080 7.96e-85 yhfM - - - - - - -
KODCOHLO_00081 1.24e-298 yhfN - - O - - - Peptidase M48
KODCOHLO_00082 1.84e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KODCOHLO_00083 1.73e-190 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KODCOHLO_00084 1.73e-133 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
KODCOHLO_00085 4.11e-252 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KODCOHLO_00086 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KODCOHLO_00087 1.86e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KODCOHLO_00088 3.24e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
KODCOHLO_00089 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
KODCOHLO_00090 3.88e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KODCOHLO_00091 3.87e-42 yhzC - - S - - - IDEAL
KODCOHLO_00093 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
KODCOHLO_00094 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KODCOHLO_00095 1.34e-235 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
KODCOHLO_00096 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KODCOHLO_00097 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
KODCOHLO_00098 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KODCOHLO_00099 7.76e-186 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KODCOHLO_00100 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KODCOHLO_00101 2.79e-198 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
KODCOHLO_00102 3.62e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KODCOHLO_00103 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KODCOHLO_00104 1.79e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
KODCOHLO_00105 2e-206 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
KODCOHLO_00106 9.13e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KODCOHLO_00107 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KODCOHLO_00108 7.88e-116 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KODCOHLO_00109 6.1e-40 yazB - - K - - - transcriptional
KODCOHLO_00110 1.03e-239 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KODCOHLO_00111 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KODCOHLO_00112 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
KODCOHLO_00113 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
KODCOHLO_00114 1.49e-180 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
KODCOHLO_00115 7.34e-100 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
KODCOHLO_00116 9.4e-156 yqxM - - - ko:K19433 - ko00000 -
KODCOHLO_00117 1.97e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
KODCOHLO_00118 2e-36 yqzE - - S - - - YqzE-like protein
KODCOHLO_00119 5.5e-80 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
KODCOHLO_00120 1.82e-84 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
KODCOHLO_00121 1.27e-25 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
KODCOHLO_00122 6.26e-91 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
KODCOHLO_00123 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
KODCOHLO_00124 1.62e-233 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
KODCOHLO_00125 5.46e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KODCOHLO_00126 2.62e-238 yqxL - - P - - - Mg2 transporter protein
KODCOHLO_00127 7.58e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KODCOHLO_00128 1.68e-189 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KODCOHLO_00130 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
KODCOHLO_00131 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
KODCOHLO_00132 3.45e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
KODCOHLO_00133 4.36e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
KODCOHLO_00134 3.5e-64 dglA - - S - - - Thiamine-binding protein
KODCOHLO_00135 8.58e-253 yqgU - - - - - - -
KODCOHLO_00136 6.09e-276 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
KODCOHLO_00137 2.05e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KODCOHLO_00138 7.5e-38 yqgQ - - S - - - Protein conserved in bacteria
KODCOHLO_00139 3.06e-300 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
KODCOHLO_00140 3.79e-11 yqgO - - - - - - -
KODCOHLO_00141 1.01e-124 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KODCOHLO_00142 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KODCOHLO_00143 3.42e-68 yqzD - - - - - - -
KODCOHLO_00144 1.02e-98 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KODCOHLO_00145 2.32e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KODCOHLO_00146 4.62e-183 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KODCOHLO_00147 3.26e-196 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
KODCOHLO_00148 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KODCOHLO_00149 9.5e-208 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KODCOHLO_00150 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
KODCOHLO_00151 9.63e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
KODCOHLO_00152 1.72e-147 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
KODCOHLO_00153 2.27e-98 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
KODCOHLO_00154 1.53e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
KODCOHLO_00155 3.05e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
KODCOHLO_00156 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KODCOHLO_00157 3.34e-80 yqfX - - S - - - membrane
KODCOHLO_00158 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
KODCOHLO_00159 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
KODCOHLO_00160 6.35e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KODCOHLO_00161 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
KODCOHLO_00162 1.65e-211 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KODCOHLO_00163 1.05e-308 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KODCOHLO_00164 4.54e-86 yqfQ - - S - - - YqfQ-like protein
KODCOHLO_00165 5.01e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KODCOHLO_00166 1.47e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KODCOHLO_00167 6e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KODCOHLO_00168 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KODCOHLO_00169 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KODCOHLO_00170 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KODCOHLO_00171 2.74e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
KODCOHLO_00172 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KODCOHLO_00173 5.89e-145 ccpN - - K - - - CBS domain
KODCOHLO_00174 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KODCOHLO_00175 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KODCOHLO_00176 5.05e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KODCOHLO_00177 6e-24 - - - S - - - YqzL-like protein
KODCOHLO_00178 8.2e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KODCOHLO_00179 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KODCOHLO_00180 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KODCOHLO_00181 1.44e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KODCOHLO_00182 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
KODCOHLO_00183 7.08e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
KODCOHLO_00184 3.72e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
KODCOHLO_00185 3.57e-61 yqfC - - S - - - sporulation protein YqfC
KODCOHLO_00186 3.47e-83 yqfB - - - - - - -
KODCOHLO_00187 1.3e-174 yqfA - - S - - - UPF0365 protein
KODCOHLO_00188 2.7e-295 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
KODCOHLO_00189 6.44e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
KODCOHLO_00190 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KODCOHLO_00191 9.26e-200 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
KODCOHLO_00192 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
KODCOHLO_00193 1.44e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KODCOHLO_00194 6.31e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
KODCOHLO_00195 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KODCOHLO_00196 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KODCOHLO_00197 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KODCOHLO_00198 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KODCOHLO_00199 1.96e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KODCOHLO_00200 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KODCOHLO_00201 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
KODCOHLO_00202 3.04e-278 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
KODCOHLO_00203 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KODCOHLO_00204 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KODCOHLO_00205 7.42e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KODCOHLO_00206 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KODCOHLO_00207 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KODCOHLO_00208 1.39e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
KODCOHLO_00209 4.85e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KODCOHLO_00210 4.86e-178 yqeM - - Q - - - Methyltransferase
KODCOHLO_00211 9.39e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KODCOHLO_00212 1.76e-130 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
KODCOHLO_00213 6.82e-139 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KODCOHLO_00214 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
KODCOHLO_00215 2.95e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KODCOHLO_00216 4.59e-271 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KODCOHLO_00217 3.19e-122 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
KODCOHLO_00219 1.2e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
KODCOHLO_00220 2.23e-178 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
KODCOHLO_00221 6.87e-137 yqeD - - S - - - SNARE associated Golgi protein
KODCOHLO_00222 2.06e-266 - - - EGP - - - Transmembrane secretion effector
KODCOHLO_00223 6.78e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KODCOHLO_00224 2.16e-203 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
KODCOHLO_00225 3.16e-119 - - - K - - - Transcriptional regulator PadR-like family
KODCOHLO_00226 1.6e-188 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
KODCOHLO_00228 1.02e-123 yqaC - - F - - - adenylate kinase activity
KODCOHLO_00229 0.000298 - - - K - - - acetyltransferase
KODCOHLO_00230 1.78e-278 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
KODCOHLO_00231 2.12e-105 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
KODCOHLO_00232 4.76e-121 - - - S - - - DinB family
KODCOHLO_00233 1.1e-185 supH - - S - - - hydrolase
KODCOHLO_00234 5.86e-187 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
KODCOHLO_00235 6.84e-167 - - - K - - - Helix-turn-helix domain, rpiR family
KODCOHLO_00236 2.23e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KODCOHLO_00237 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KODCOHLO_00238 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
KODCOHLO_00239 4.05e-230 romA - - S - - - Beta-lactamase superfamily domain
KODCOHLO_00240 1.27e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KODCOHLO_00241 6.22e-210 yybE - - K - - - Transcriptional regulator
KODCOHLO_00242 1.53e-269 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KODCOHLO_00243 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
KODCOHLO_00244 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
KODCOHLO_00245 1.28e-120 yrhH - - Q - - - methyltransferase
KODCOHLO_00246 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
KODCOHLO_00247 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
KODCOHLO_00248 1.48e-78 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
KODCOHLO_00249 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
KODCOHLO_00250 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
KODCOHLO_00251 5.51e-46 yrhC - - S - - - YrhC-like protein
KODCOHLO_00252 7.59e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KODCOHLO_00253 1.54e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
KODCOHLO_00254 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KODCOHLO_00255 1.35e-150 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
KODCOHLO_00256 2.53e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
KODCOHLO_00257 3.56e-124 yrrS - - S - - - Protein of unknown function (DUF1510)
KODCOHLO_00258 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
KODCOHLO_00259 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KODCOHLO_00260 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KODCOHLO_00261 1.8e-310 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
KODCOHLO_00262 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KODCOHLO_00263 6.65e-153 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
KODCOHLO_00264 7.74e-257 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KODCOHLO_00265 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
KODCOHLO_00266 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KODCOHLO_00267 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
KODCOHLO_00268 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KODCOHLO_00269 4.47e-235 yrrI - - S - - - AI-2E family transporter
KODCOHLO_00270 3.66e-167 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KODCOHLO_00271 2.12e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KODCOHLO_00272 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KODCOHLO_00273 8.88e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KODCOHLO_00274 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
KODCOHLO_00275 8.4e-42 yrzR - - - - - - -
KODCOHLO_00276 1.69e-105 yrrD - - S - - - protein conserved in bacteria
KODCOHLO_00277 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KODCOHLO_00278 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
KODCOHLO_00279 5.88e-281 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KODCOHLO_00280 2.98e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KODCOHLO_00281 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_00282 3.74e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KODCOHLO_00283 1.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KODCOHLO_00284 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KODCOHLO_00285 1e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KODCOHLO_00288 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
KODCOHLO_00289 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KODCOHLO_00290 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KODCOHLO_00291 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KODCOHLO_00292 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KODCOHLO_00293 7.78e-63 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
KODCOHLO_00294 8.88e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
KODCOHLO_00295 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KODCOHLO_00296 4.04e-67 yrzD - - S - - - Post-transcriptional regulator
KODCOHLO_00297 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KODCOHLO_00298 2.03e-143 yrbG - - S - - - membrane
KODCOHLO_00299 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
KODCOHLO_00300 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
KODCOHLO_00301 8.2e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KODCOHLO_00302 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KODCOHLO_00303 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
KODCOHLO_00304 3.57e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KODCOHLO_00305 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KODCOHLO_00306 1.03e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
KODCOHLO_00308 1.91e-62 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KODCOHLO_00309 1.2e-232 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
KODCOHLO_00310 2.02e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KODCOHLO_00311 4.31e-195 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
KODCOHLO_00312 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
KODCOHLO_00313 6.4e-282 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KODCOHLO_00314 6.84e-121 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
KODCOHLO_00315 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KODCOHLO_00316 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
KODCOHLO_00317 2.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KODCOHLO_00318 3.5e-138 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
KODCOHLO_00319 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KODCOHLO_00320 6.76e-73 ysxB - - J ko:K07584 - ko00000 ribosomal protein
KODCOHLO_00321 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KODCOHLO_00322 5.1e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
KODCOHLO_00323 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KODCOHLO_00324 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
KODCOHLO_00325 6.85e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KODCOHLO_00326 1.76e-110 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
KODCOHLO_00327 2.51e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KODCOHLO_00328 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
KODCOHLO_00329 7.15e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
KODCOHLO_00330 1.53e-126 maf - - D ko:K06287 - ko00000 septum formation protein Maf
KODCOHLO_00331 6e-207 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
KODCOHLO_00332 4.26e-170 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KODCOHLO_00333 1.47e-304 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KODCOHLO_00334 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KODCOHLO_00335 1.53e-35 - - - - - - - -
KODCOHLO_00336 6.33e-250 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KODCOHLO_00337 1.02e-171 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
KODCOHLO_00338 4.95e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KODCOHLO_00339 1.85e-202 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KODCOHLO_00340 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KODCOHLO_00341 3.52e-105 - - - - - - - -
KODCOHLO_00342 5.29e-121 ywhD - - S - - - YwhD family
KODCOHLO_00343 1.56e-152 ywhC - - S - - - Peptidase family M50
KODCOHLO_00344 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
KODCOHLO_00345 9.43e-90 ywhA - - K - - - Transcriptional regulator
KODCOHLO_00346 1.91e-313 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
KODCOHLO_00347 8.24e-115 ywgA - - - ko:K09388 - ko00000 -
KODCOHLO_00348 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
KODCOHLO_00349 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
KODCOHLO_00350 2.89e-144 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
KODCOHLO_00351 9.26e-69 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
KODCOHLO_00352 3.1e-119 - - - S - - - membrane
KODCOHLO_00353 2.61e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_00354 1.4e-213 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
KODCOHLO_00357 1.3e-225 - - - - - - - -
KODCOHLO_00359 2.41e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KODCOHLO_00360 2.25e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_00361 4.85e-213 - - - S - - - Conserved hypothetical protein 698
KODCOHLO_00362 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
KODCOHLO_00363 1.98e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
KODCOHLO_00364 8.07e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
KODCOHLO_00365 2.21e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
KODCOHLO_00366 4.71e-264 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
KODCOHLO_00367 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KODCOHLO_00368 2.21e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KODCOHLO_00369 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KODCOHLO_00370 1.4e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KODCOHLO_00371 1.58e-283 ywfA - - EGP - - - -transporter
KODCOHLO_00372 5.71e-264 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
KODCOHLO_00373 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KODCOHLO_00374 0.0 rocB - - E - - - arginine degradation protein
KODCOHLO_00375 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KODCOHLO_00376 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KODCOHLO_00377 6.37e-77 - - - - - - - -
KODCOHLO_00378 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
KODCOHLO_00379 1.59e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KODCOHLO_00380 1.51e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KODCOHLO_00381 6.62e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KODCOHLO_00382 3.01e-228 spsG - - M - - - Spore Coat
KODCOHLO_00383 1.68e-170 spsF - - M ko:K07257 - ko00000 Spore Coat
KODCOHLO_00384 1.18e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
KODCOHLO_00385 1.45e-200 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
KODCOHLO_00386 1.39e-279 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
KODCOHLO_00387 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
KODCOHLO_00388 9.06e-184 spsA - - M - - - Spore Coat
KODCOHLO_00389 4.89e-85 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KODCOHLO_00390 2.17e-76 ywdK - - S - - - small membrane protein
KODCOHLO_00391 2.19e-290 ywdJ - - F - - - Xanthine uracil
KODCOHLO_00392 1.57e-62 ywdI - - S - - - Family of unknown function (DUF5327)
KODCOHLO_00393 8.43e-170 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KODCOHLO_00394 4.49e-190 ywdF - - S - - - Glycosyltransferase like family 2
KODCOHLO_00396 8.16e-115 ywdD - - - - - - -
KODCOHLO_00397 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
KODCOHLO_00398 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KODCOHLO_00399 5e-26 ywdA - - - - - - -
KODCOHLO_00400 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KODCOHLO_00401 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KODCOHLO_00402 1.91e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KODCOHLO_00404 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KODCOHLO_00405 1.15e-236 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KODCOHLO_00406 4.47e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
KODCOHLO_00407 7.63e-271 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KODCOHLO_00408 7.5e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
KODCOHLO_00409 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
KODCOHLO_00410 6.76e-84 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KODCOHLO_00411 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KODCOHLO_00412 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KODCOHLO_00413 3.67e-227 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KODCOHLO_00414 5.74e-48 ydaS - - S - - - membrane
KODCOHLO_00415 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KODCOHLO_00416 1.16e-79 gtcA - - S - - - GtrA-like protein
KODCOHLO_00417 1.52e-144 - - - K - - - Bacterial regulatory proteins, tetR family
KODCOHLO_00419 3.57e-166 - - - H - - - Methionine biosynthesis protein MetW
KODCOHLO_00420 3.31e-170 - - - S - - - Streptomycin biosynthesis protein StrF
KODCOHLO_00421 1.21e-142 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KODCOHLO_00422 5.83e-274 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
KODCOHLO_00423 2.87e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KODCOHLO_00424 1.52e-174 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KODCOHLO_00425 4.83e-202 ywbI - - K - - - Transcriptional regulator
KODCOHLO_00426 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KODCOHLO_00427 7.55e-143 ywbG - - M - - - effector of murein hydrolase
KODCOHLO_00428 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
KODCOHLO_00429 4.11e-174 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
KODCOHLO_00430 1.03e-284 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
KODCOHLO_00431 1.51e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
KODCOHLO_00432 9.46e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KODCOHLO_00433 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KODCOHLO_00434 1.42e-205 gspA - - M - - - General stress
KODCOHLO_00435 2.16e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
KODCOHLO_00436 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
KODCOHLO_00437 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
KODCOHLO_00438 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_00439 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
KODCOHLO_00440 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_00441 1.79e-288 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KODCOHLO_00442 9.09e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KODCOHLO_00443 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KODCOHLO_00444 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KODCOHLO_00445 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KODCOHLO_00446 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
KODCOHLO_00447 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
KODCOHLO_00448 4.59e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KODCOHLO_00449 1.15e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KODCOHLO_00450 9.74e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KODCOHLO_00451 5.34e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KODCOHLO_00452 2.15e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
KODCOHLO_00453 6.3e-291 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KODCOHLO_00454 9.69e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KODCOHLO_00455 1.53e-63 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KODCOHLO_00456 8.17e-302 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KODCOHLO_00457 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KODCOHLO_00458 7e-211 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
KODCOHLO_00459 2.24e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KODCOHLO_00460 6.21e-266 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
KODCOHLO_00461 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KODCOHLO_00462 7.89e-246 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
KODCOHLO_00463 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
KODCOHLO_00464 7.23e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KODCOHLO_00465 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
KODCOHLO_00466 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
KODCOHLO_00467 3.07e-239 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
KODCOHLO_00468 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KODCOHLO_00469 9.15e-287 cimH - - C - - - COG3493 Na citrate symporter
KODCOHLO_00470 2.71e-197 yxkH - - G - - - Polysaccharide deacetylase
KODCOHLO_00471 8.75e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_00472 2.25e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
KODCOHLO_00473 3.28e-189 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KODCOHLO_00474 3.64e-118 yxkC - - S - - - Domain of unknown function (DUF4352)
KODCOHLO_00475 6.27e-248 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KODCOHLO_00476 5.46e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KODCOHLO_00479 4.3e-111 yxjI - - S - - - LURP-one-related
KODCOHLO_00480 1.28e-274 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KODCOHLO_00481 4e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
KODCOHLO_00482 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KODCOHLO_00483 1.33e-82 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
KODCOHLO_00484 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KODCOHLO_00485 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
KODCOHLO_00486 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KODCOHLO_00487 8.93e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KODCOHLO_00488 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
KODCOHLO_00489 1.01e-159 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KODCOHLO_00490 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KODCOHLO_00491 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KODCOHLO_00492 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
KODCOHLO_00493 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KODCOHLO_00494 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KODCOHLO_00495 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KODCOHLO_00496 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
KODCOHLO_00497 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
KODCOHLO_00498 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KODCOHLO_00499 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KODCOHLO_00500 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KODCOHLO_00501 3.53e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KODCOHLO_00502 8.13e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KODCOHLO_00503 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KODCOHLO_00504 2.95e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
KODCOHLO_00505 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KODCOHLO_00506 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KODCOHLO_00507 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
KODCOHLO_00508 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KODCOHLO_00509 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KODCOHLO_00510 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KODCOHLO_00511 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KODCOHLO_00512 2.41e-232 ybaC - - S - - - Alpha/beta hydrolase family
KODCOHLO_00513 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KODCOHLO_00514 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KODCOHLO_00515 2.59e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KODCOHLO_00516 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KODCOHLO_00517 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KODCOHLO_00518 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KODCOHLO_00519 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KODCOHLO_00520 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KODCOHLO_00521 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KODCOHLO_00522 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KODCOHLO_00523 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KODCOHLO_00524 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KODCOHLO_00525 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KODCOHLO_00526 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KODCOHLO_00527 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KODCOHLO_00528 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KODCOHLO_00529 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KODCOHLO_00530 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KODCOHLO_00531 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KODCOHLO_00532 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KODCOHLO_00533 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KODCOHLO_00534 3.15e-295 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KODCOHLO_00535 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KODCOHLO_00536 2.71e-181 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KODCOHLO_00537 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KODCOHLO_00538 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KODCOHLO_00539 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KODCOHLO_00540 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KODCOHLO_00541 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KODCOHLO_00542 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KODCOHLO_00543 7.19e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KODCOHLO_00544 1.41e-189 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KODCOHLO_00545 2.77e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KODCOHLO_00546 1.69e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KODCOHLO_00547 6.54e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KODCOHLO_00548 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KODCOHLO_00549 1.02e-184 ybaJ - - Q - - - Methyltransferase domain
KODCOHLO_00550 3.15e-108 yizA - - S - - - Damage-inducible protein DinB
KODCOHLO_00551 3.1e-101 ybaK - - S - - - Protein of unknown function (DUF2521)
KODCOHLO_00552 5.68e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KODCOHLO_00553 6.33e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KODCOHLO_00554 3.93e-102 gerD - - - ko:K06294 - ko00000 -
KODCOHLO_00555 1.78e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
KODCOHLO_00556 3.54e-180 pdaB - - G - - - Polysaccharide deacetylase
KODCOHLO_00557 5.72e-124 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
KODCOHLO_00558 3.08e-277 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
KODCOHLO_00559 4.61e-108 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
KODCOHLO_00560 1.66e-101 yuaE - - S - - - DinB superfamily
KODCOHLO_00561 3.93e-140 - - - S - - - MOSC domain
KODCOHLO_00562 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
KODCOHLO_00563 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KODCOHLO_00564 1.67e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
KODCOHLO_00565 4.1e-122 yuaB - - - - - - -
KODCOHLO_00566 1.76e-155 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KODCOHLO_00567 8.63e-190 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KODCOHLO_00568 4.34e-280 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KODCOHLO_00569 8.44e-154 - - - G - - - Cupin
KODCOHLO_00570 1.71e-65 yjcN - - - - - - -
KODCOHLO_00572 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KODCOHLO_00573 5.75e-250 yubA - - S - - - transporter activity
KODCOHLO_00574 1.35e-237 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KODCOHLO_00575 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
KODCOHLO_00576 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KODCOHLO_00577 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KODCOHLO_00578 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KODCOHLO_00579 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KODCOHLO_00580 6.36e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
KODCOHLO_00581 9.36e-55 - - - - - - - -
KODCOHLO_00582 1.16e-241 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KODCOHLO_00583 7.42e-96 yugU - - S - - - Uncharacterised protein family UPF0047
KODCOHLO_00584 7.61e-161 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KODCOHLO_00585 6.25e-244 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KODCOHLO_00586 7.73e-295 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KODCOHLO_00587 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
KODCOHLO_00588 3.06e-23 - - - - - - - -
KODCOHLO_00589 3.47e-35 mstX - - S - - - Membrane-integrating protein Mistic
KODCOHLO_00590 1.39e-230 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
KODCOHLO_00591 1.17e-92 yugN - - S - - - YugN-like family
KODCOHLO_00593 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KODCOHLO_00594 2.21e-59 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
KODCOHLO_00595 1.02e-150 ycaC - - Q - - - Isochorismatase family
KODCOHLO_00596 9.22e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
KODCOHLO_00597 3.88e-285 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
KODCOHLO_00598 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
KODCOHLO_00599 1.43e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KODCOHLO_00600 6.82e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
KODCOHLO_00601 3.75e-109 alaR - - K - - - Transcriptional regulator
KODCOHLO_00602 4.71e-199 yugF - - I - - - Hydrolase
KODCOHLO_00603 4.25e-55 yugE - - S - - - Domain of unknown function (DUF1871)
KODCOHLO_00604 4.34e-282 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KODCOHLO_00605 8.61e-291 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_00606 3.28e-87 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
KODCOHLO_00607 2.64e-153 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
KODCOHLO_00608 1.84e-263 yuxJ - - EGP - - - Major facilitator superfamily
KODCOHLO_00609 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
KODCOHLO_00610 2.62e-95 yuxK - - S - - - protein conserved in bacteria
KODCOHLO_00611 7.81e-46 yufK - - S - - - Family of unknown function (DUF5366)
KODCOHLO_00612 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KODCOHLO_00613 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
KODCOHLO_00614 1.12e-246 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
KODCOHLO_00615 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_00616 2.23e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KODCOHLO_00617 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KODCOHLO_00619 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KODCOHLO_00620 5.18e-89 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KODCOHLO_00621 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KODCOHLO_00622 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KODCOHLO_00623 9.67e-99 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KODCOHLO_00624 1.1e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KODCOHLO_00625 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
KODCOHLO_00626 2.71e-81 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
KODCOHLO_00627 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KODCOHLO_00628 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_00630 2.7e-76 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
KODCOHLO_00631 2.66e-11 - - - S - - - DegQ (SacQ) family
KODCOHLO_00633 6.01e-67 yuzC - - - - - - -
KODCOHLO_00634 6.32e-294 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
KODCOHLO_00635 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KODCOHLO_00636 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
KODCOHLO_00637 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
KODCOHLO_00638 2.23e-50 yueH - - S - - - YueH-like protein
KODCOHLO_00639 9e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
KODCOHLO_00640 8.88e-237 yueF - - S - - - transporter activity
KODCOHLO_00641 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
KODCOHLO_00642 2.23e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
KODCOHLO_00643 1.18e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KODCOHLO_00644 1.09e-99 yueC - - S - - - Family of unknown function (DUF5383)
KODCOHLO_00645 0.0 yueB - - S - - - type VII secretion protein EsaA
KODCOHLO_00646 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KODCOHLO_00647 1.2e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
KODCOHLO_00648 9.1e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
KODCOHLO_00649 2.36e-61 yukE - - S - - - Belongs to the WXG100 family
KODCOHLO_00650 2.11e-291 yukF - - QT - - - Transcriptional regulator
KODCOHLO_00651 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
KODCOHLO_00652 9.86e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
KODCOHLO_00653 2.24e-45 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
KODCOHLO_00654 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_00655 1.87e-218 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
KODCOHLO_00656 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
KODCOHLO_00657 9.41e-278 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KODCOHLO_00658 5.57e-168 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KODCOHLO_00659 2.85e-208 eSD - - S ko:K07017 - ko00000 Putative esterase
KODCOHLO_00660 4.59e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
KODCOHLO_00661 5.29e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
KODCOHLO_00662 9.54e-275 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
KODCOHLO_00663 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KODCOHLO_00664 7.09e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
KODCOHLO_00665 2.42e-153 yuiC - - S - - - protein conserved in bacteria
KODCOHLO_00666 8.54e-46 yuiB - - S - - - Putative membrane protein
KODCOHLO_00667 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KODCOHLO_00668 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
KODCOHLO_00670 7.47e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KODCOHLO_00671 5.68e-40 - - - - - - - -
KODCOHLO_00672 1.63e-90 - - - CP - - - Membrane
KODCOHLO_00673 1.08e-155 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KODCOHLO_00675 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
KODCOHLO_00677 1.67e-35 - - - K - - - helix_turn_helix, mercury resistance
KODCOHLO_00678 7.1e-175 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KODCOHLO_00679 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
KODCOHLO_00680 2.63e-206 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KODCOHLO_00681 4.26e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KODCOHLO_00682 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
KODCOHLO_00683 1.71e-265 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KODCOHLO_00684 5.46e-72 yuzD - - S - - - protein conserved in bacteria
KODCOHLO_00685 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
KODCOHLO_00686 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
KODCOHLO_00687 4.56e-215 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KODCOHLO_00688 7.68e-250 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KODCOHLO_00689 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KODCOHLO_00690 1.22e-247 yutH - - S - - - Spore coat protein
KODCOHLO_00691 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
KODCOHLO_00692 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KODCOHLO_00693 3e-93 yutE - - S - - - Protein of unknown function DUF86
KODCOHLO_00694 3.71e-62 yutD - - S - - - protein conserved in bacteria
KODCOHLO_00695 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KODCOHLO_00696 6.78e-250 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
KODCOHLO_00697 7.89e-167 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
KODCOHLO_00698 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KODCOHLO_00699 4.99e-185 yunE - - S ko:K07090 - ko00000 membrane transporter protein
KODCOHLO_00700 6.03e-216 yunF - - S - - - Protein of unknown function DUF72
KODCOHLO_00701 4.62e-65 - - - S - - - phosphoglycolate phosphatase activity
KODCOHLO_00702 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KODCOHLO_00703 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
KODCOHLO_00707 3.51e-273 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
KODCOHLO_00708 5.7e-300 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KODCOHLO_00709 4.87e-299 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KODCOHLO_00710 5.35e-213 bsn - - L - - - Ribonuclease
KODCOHLO_00711 1.3e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_00712 5.89e-173 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
KODCOHLO_00713 1.78e-204 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
KODCOHLO_00714 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
KODCOHLO_00715 1.24e-201 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KODCOHLO_00716 8.64e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
KODCOHLO_00717 1.35e-237 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KODCOHLO_00718 1.84e-209 - - - K - - - helix_turn_helix, mercury resistance
KODCOHLO_00720 2.74e-84 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
KODCOHLO_00721 4.82e-255 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
KODCOHLO_00722 2.75e-33 yncE - - S - - - Protein of unknown function (DUF2691)
KODCOHLO_00723 1.25e-201 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KODCOHLO_00724 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
KODCOHLO_00725 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
KODCOHLO_00726 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KODCOHLO_00727 5.01e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
KODCOHLO_00728 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KODCOHLO_00729 2.54e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KODCOHLO_00730 5.2e-186 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KODCOHLO_00731 2.08e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
KODCOHLO_00732 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KODCOHLO_00733 5.28e-76 yusD - - S - - - SCP-2 sterol transfer family
KODCOHLO_00734 1.64e-72 yusE - - CO - - - Thioredoxin
KODCOHLO_00735 2.17e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
KODCOHLO_00736 3.1e-55 yusG - - S - - - Protein of unknown function (DUF2553)
KODCOHLO_00737 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KODCOHLO_00738 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
KODCOHLO_00739 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KODCOHLO_00740 7.74e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
KODCOHLO_00741 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
KODCOHLO_00742 9.92e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KODCOHLO_00743 6.38e-263 yusP - - P - - - Major facilitator superfamily
KODCOHLO_00744 6.46e-58 - - - - - - - -
KODCOHLO_00745 4.46e-72 yusN - - M - - - Coat F domain
KODCOHLO_00746 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
KODCOHLO_00747 0.0 yusP - - P - - - Major facilitator superfamily
KODCOHLO_00748 5.44e-200 - - - K - - - Transcriptional regulator
KODCOHLO_00749 1.19e-175 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
KODCOHLO_00750 1.83e-235 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KODCOHLO_00751 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
KODCOHLO_00752 5.24e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KODCOHLO_00753 7.61e-60 - - - S - - - YusW-like protein
KODCOHLO_00754 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
KODCOHLO_00755 5.87e-192 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KODCOHLO_00756 8.32e-103 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KODCOHLO_00757 1.08e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KODCOHLO_00758 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KODCOHLO_00759 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_00760 4.63e-33 - - - - - - - -
KODCOHLO_00761 7.31e-200 yuxN - - K - - - Transcriptional regulator
KODCOHLO_00762 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KODCOHLO_00763 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
KODCOHLO_00764 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KODCOHLO_00765 2.07e-242 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
KODCOHLO_00766 1.07e-262 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
KODCOHLO_00767 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KODCOHLO_00768 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_00769 8.92e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
KODCOHLO_00770 5.11e-186 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
KODCOHLO_00771 3.63e-129 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KODCOHLO_00772 2.21e-66 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
KODCOHLO_00773 3.93e-289 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KODCOHLO_00774 1.79e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
KODCOHLO_00775 1.24e-278 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KODCOHLO_00776 5.14e-227 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KODCOHLO_00777 2.25e-213 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KODCOHLO_00778 8.63e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KODCOHLO_00779 3.64e-217 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
KODCOHLO_00780 0.0 yvrG - - T - - - Histidine kinase
KODCOHLO_00781 1.56e-171 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KODCOHLO_00782 1.67e-50 - - - - - - - -
KODCOHLO_00783 1.31e-133 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
KODCOHLO_00784 1.88e-21 - - - S - - - YvrJ protein family
KODCOHLO_00785 2.1e-293 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
KODCOHLO_00786 8.03e-87 yvrL - - S - - - Regulatory protein YrvL
KODCOHLO_00787 1.02e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KODCOHLO_00788 4.58e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KODCOHLO_00789 1.56e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KODCOHLO_00790 2.59e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KODCOHLO_00791 5.06e-159 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KODCOHLO_00792 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
KODCOHLO_00793 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
KODCOHLO_00794 8.3e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
KODCOHLO_00795 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
KODCOHLO_00796 4.72e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
KODCOHLO_00797 1.13e-177 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
KODCOHLO_00798 5.72e-127 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
KODCOHLO_00799 5.32e-147 yfiK - - K - - - Regulator
KODCOHLO_00800 4.77e-250 - - - T - - - Histidine kinase
KODCOHLO_00801 2.17e-214 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
KODCOHLO_00802 1.36e-246 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KODCOHLO_00803 1.49e-254 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KODCOHLO_00804 5.09e-200 yvgN - - S - - - reductase
KODCOHLO_00805 1.32e-111 yvgO - - - - - - -
KODCOHLO_00806 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
KODCOHLO_00807 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KODCOHLO_00808 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KODCOHLO_00809 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KODCOHLO_00810 2.48e-127 yvgT - - S - - - membrane
KODCOHLO_00811 1.34e-190 - - - S - - - Metallo-peptidase family M12
KODCOHLO_00812 3.05e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
KODCOHLO_00813 5.06e-135 bdbD - - O - - - Thioredoxin
KODCOHLO_00814 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
KODCOHLO_00815 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KODCOHLO_00816 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
KODCOHLO_00817 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
KODCOHLO_00818 1.12e-245 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KODCOHLO_00819 1.43e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KODCOHLO_00821 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KODCOHLO_00822 2.9e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
KODCOHLO_00823 3.04e-233 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KODCOHLO_00824 3.01e-179 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KODCOHLO_00825 8.24e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KODCOHLO_00826 2e-154 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KODCOHLO_00827 4.13e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KODCOHLO_00828 2.8e-166 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KODCOHLO_00829 3.16e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KODCOHLO_00830 3.41e-207 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
KODCOHLO_00831 3.94e-180 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KODCOHLO_00832 9.79e-65 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
KODCOHLO_00833 8.71e-06 - - - - - - - -
KODCOHLO_00834 6.18e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
KODCOHLO_00835 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KODCOHLO_00836 3.18e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
KODCOHLO_00837 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KODCOHLO_00838 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KODCOHLO_00839 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
KODCOHLO_00840 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KODCOHLO_00841 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KODCOHLO_00842 2.73e-207 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KODCOHLO_00843 1.54e-82 yqhP - - - - - - -
KODCOHLO_00844 1.21e-219 yqhQ - - S - - - Protein of unknown function (DUF1385)
KODCOHLO_00845 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
KODCOHLO_00846 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KODCOHLO_00847 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KODCOHLO_00848 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
KODCOHLO_00849 1.8e-220 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
KODCOHLO_00850 1.91e-109 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
KODCOHLO_00851 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
KODCOHLO_00852 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
KODCOHLO_00853 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
KODCOHLO_00854 3.01e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
KODCOHLO_00855 7.86e-147 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
KODCOHLO_00856 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
KODCOHLO_00857 1.63e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KODCOHLO_00858 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KODCOHLO_00859 1.36e-87 yqhY - - S - - - protein conserved in bacteria
KODCOHLO_00860 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KODCOHLO_00861 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KODCOHLO_00862 8.28e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KODCOHLO_00863 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KODCOHLO_00864 6.4e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KODCOHLO_00865 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KODCOHLO_00866 2.06e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
KODCOHLO_00867 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KODCOHLO_00868 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KODCOHLO_00869 2.08e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
KODCOHLO_00870 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KODCOHLO_00871 1.68e-273 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KODCOHLO_00874 5.59e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KODCOHLO_00876 6.65e-145 - - - K - - - Protein of unknown function (DUF1232)
KODCOHLO_00877 1.61e-130 - - - P - - - Probably functions as a manganese efflux pump
KODCOHLO_00879 1.39e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
KODCOHLO_00880 1.5e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KODCOHLO_00881 7.62e-270 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KODCOHLO_00882 6.16e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
KODCOHLO_00883 8.39e-259 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
KODCOHLO_00884 6.65e-259 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KODCOHLO_00885 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
KODCOHLO_00886 4.47e-202 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KODCOHLO_00887 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
KODCOHLO_00888 0.0 bkdR - - KT - - - Transcriptional regulator
KODCOHLO_00889 2.27e-193 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
KODCOHLO_00890 1.58e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KODCOHLO_00891 1.57e-259 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
KODCOHLO_00892 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KODCOHLO_00893 1.86e-220 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KODCOHLO_00894 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KODCOHLO_00895 3.44e-282 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KODCOHLO_00896 1.09e-217 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KODCOHLO_00897 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
KODCOHLO_00898 1.37e-173 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KODCOHLO_00899 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KODCOHLO_00900 6.07e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KODCOHLO_00901 3.22e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
KODCOHLO_00902 3.7e-123 yqjB - - S - - - protein conserved in bacteria
KODCOHLO_00904 2.21e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
KODCOHLO_00905 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KODCOHLO_00906 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
KODCOHLO_00907 2.91e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KODCOHLO_00908 1.3e-34 yqzJ - - - - - - -
KODCOHLO_00909 1.35e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KODCOHLO_00910 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KODCOHLO_00911 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KODCOHLO_00912 3.23e-219 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KODCOHLO_00914 1.24e-186 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KODCOHLO_00915 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KODCOHLO_00916 2.62e-65 - - - S - - - GlpM protein
KODCOHLO_00917 6.96e-206 - - - K - - - LysR substrate binding domain
KODCOHLO_00918 4.32e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KODCOHLO_00919 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KODCOHLO_00922 4.54e-313 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KODCOHLO_00923 1.54e-165 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KODCOHLO_00924 1.55e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KODCOHLO_00925 1.29e-93 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KODCOHLO_00926 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KODCOHLO_00927 6.11e-36 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
KODCOHLO_00929 5.12e-25 yycC - - K - - - YycC-like protein
KODCOHLO_00930 3.87e-300 - - - M - - - Glycosyltransferase Family 4
KODCOHLO_00931 4.31e-257 - - - S - - - Ecdysteroid kinase
KODCOHLO_00932 1.27e-294 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
KODCOHLO_00933 1.18e-308 - - - M - - - Glycosyltransferase Family 4
KODCOHLO_00934 2.15e-157 - - - S - - - GlcNAc-PI de-N-acetylase
KODCOHLO_00935 2.06e-158 - - - KLT - - - COG0515 Serine threonine protein kinase
KODCOHLO_00936 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KODCOHLO_00937 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KODCOHLO_00938 2.9e-203 yybS - - S - - - membrane
KODCOHLO_00940 3.2e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
KODCOHLO_00941 2.64e-86 yybR - - K - - - Transcriptional regulator
KODCOHLO_00942 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
KODCOHLO_00943 4.82e-196 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KODCOHLO_00944 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
KODCOHLO_00945 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KODCOHLO_00946 2.21e-148 - - - K - - - FCD domain
KODCOHLO_00947 1.33e-99 - - - S - - - PFAM DinB family protein
KODCOHLO_00948 8.38e-202 - - - G - - - Major Facilitator Superfamily
KODCOHLO_00949 1.12e-73 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
KODCOHLO_00950 1.7e-148 ydgI - - C - - - nitroreductase
KODCOHLO_00951 6.79e-90 - - - K - - - Winged helix DNA-binding domain
KODCOHLO_00952 4.43e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KODCOHLO_00953 1.85e-99 yybA - - K - - - transcriptional
KODCOHLO_00954 2.56e-55 yjcF - - S - - - Acetyltransferase (GNAT) domain
KODCOHLO_00955 3.12e-08 yjcF - - S - - - Acetyltransferase (GNAT) domain
KODCOHLO_00956 1.12e-209 - - - M - - - Domain of Unknown Function (DUF1259)
KODCOHLO_00957 4.76e-87 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KODCOHLO_00958 1.1e-206 - - - K - - - Transcriptional regulator
KODCOHLO_00959 3.14e-170 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KODCOHLO_00960 1.05e-122 - - - - - - - -
KODCOHLO_00961 2.69e-86 - - - S - - - Leucine-rich repeat (LRR) protein
KODCOHLO_00963 2.41e-86 - - - O ko:K13275,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KODCOHLO_00964 5.52e-315 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KODCOHLO_00965 2.01e-163 - - - EG - - - EamA-like transporter family
KODCOHLO_00966 8.3e-128 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KODCOHLO_00967 1.76e-101 - - - K - - - Transcriptional regulator
KODCOHLO_00968 1.9e-31 - - - K - - - Transcriptional
KODCOHLO_00969 9.62e-52 - - - E - - - Pfam:DUF955
KODCOHLO_00970 2.32e-52 ebrA - - U ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KODCOHLO_00971 1.3e-31 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
KODCOHLO_00972 3.81e-144 - - - K - - - Bacterial transcription activator, effector binding domain
KODCOHLO_00973 3.3e-127 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KODCOHLO_00974 3.45e-30 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
KODCOHLO_00975 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
KODCOHLO_00976 5.73e-208 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
KODCOHLO_00977 7.51e-316 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
KODCOHLO_00978 3.43e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KODCOHLO_00979 3.83e-229 ccpB - - K - - - Transcriptional regulator
KODCOHLO_00980 1.83e-181 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KODCOHLO_00981 2.28e-126 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KODCOHLO_00982 2.1e-135 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
KODCOHLO_00983 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KODCOHLO_00984 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KODCOHLO_00985 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KODCOHLO_00986 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KODCOHLO_00987 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KODCOHLO_00988 5.21e-45 yyzM - - S - - - protein conserved in bacteria
KODCOHLO_00989 1.67e-225 yyaD - - S - - - Membrane
KODCOHLO_00990 1.97e-72 yhhY - - K - - - FR47-like protein
KODCOHLO_00991 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
KODCOHLO_00992 1.43e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KODCOHLO_00993 2.49e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
KODCOHLO_00994 6.61e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KODCOHLO_00995 2.67e-163 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KODCOHLO_00996 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KODCOHLO_00997 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KODCOHLO_00998 4.45e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
KODCOHLO_00999 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KODCOHLO_01000 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KODCOHLO_01001 5.59e-316 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KODCOHLO_01002 2.33e-261 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KODCOHLO_01003 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
KODCOHLO_01004 1.52e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KODCOHLO_01005 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
KODCOHLO_01006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KODCOHLO_01007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KODCOHLO_01008 1.24e-160 - - - S - - - Bacterial EndoU nuclease
KODCOHLO_01009 1.89e-40 - - - - - - - -
KODCOHLO_01011 3.29e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KODCOHLO_01012 7.6e-269 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KODCOHLO_01013 1.43e-163 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
KODCOHLO_01014 2.43e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
KODCOHLO_01015 1.18e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KODCOHLO_01016 3.02e-176 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
KODCOHLO_01017 5e-48 - - - - - - - -
KODCOHLO_01018 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KODCOHLO_01019 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
KODCOHLO_01023 3.41e-72 yjcA - - S - - - Protein of unknown function (DUF1360)
KODCOHLO_01024 2.67e-68 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
KODCOHLO_01025 8.38e-36 cotW - - - ko:K06341 - ko00000 -
KODCOHLO_01026 2.61e-100 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
KODCOHLO_01027 4.28e-121 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
KODCOHLO_01028 2.1e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
KODCOHLO_01029 1.92e-120 yjbX - - S - - - Spore coat protein
KODCOHLO_01030 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KODCOHLO_01031 1.23e-188 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KODCOHLO_01032 2.52e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KODCOHLO_01033 7.36e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KODCOHLO_01034 4.53e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
KODCOHLO_01035 1.08e-266 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
KODCOHLO_01036 4.68e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
KODCOHLO_01037 2.23e-174 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KODCOHLO_01038 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KODCOHLO_01039 1.24e-182 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KODCOHLO_01040 5.76e-212 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KODCOHLO_01041 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KODCOHLO_01042 9.01e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
KODCOHLO_01043 2.03e-80 yjbL - - S - - - Belongs to the UPF0738 family
KODCOHLO_01044 3.34e-124 yjbK - - S - - - protein conserved in bacteria
KODCOHLO_01045 8.57e-150 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KODCOHLO_01046 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
KODCOHLO_01047 6.05e-220 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KODCOHLO_01048 3.14e-27 - - - - - - - -
KODCOHLO_01049 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KODCOHLO_01050 1.18e-274 coiA - - S ko:K06198 - ko00000 Competence protein
KODCOHLO_01051 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KODCOHLO_01052 5.59e-141 yjbE - - P - - - Integral membrane protein TerC family
KODCOHLO_01053 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KODCOHLO_01054 7.3e-131 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KODCOHLO_01055 1.17e-293 - - - S - - - Putative glycosyl hydrolase domain
KODCOHLO_01056 1.22e-217 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_01057 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_01058 5.09e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KODCOHLO_01059 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KODCOHLO_01060 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KODCOHLO_01061 1.45e-233 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
KODCOHLO_01062 1.52e-188 yjbA - - S - - - Belongs to the UPF0736 family
KODCOHLO_01063 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KODCOHLO_01064 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KODCOHLO_01065 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
KODCOHLO_01066 8.8e-239 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_01067 4.84e-231 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_01068 1.84e-190 yjaZ - - O - - - Zn-dependent protease
KODCOHLO_01069 3.86e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KODCOHLO_01070 7.63e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KODCOHLO_01071 8.09e-44 yjzB - - - - - - -
KODCOHLO_01072 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
KODCOHLO_01073 2.22e-211 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
KODCOHLO_01074 2.77e-133 yjaV - - - - - - -
KODCOHLO_01075 4.49e-178 yjaU - - I - - - carboxylic ester hydrolase activity
KODCOHLO_01076 1.06e-32 yjzD - - S - - - Protein of unknown function (DUF2929)
KODCOHLO_01077 7.21e-39 yjzC - - S - - - YjzC-like protein
KODCOHLO_01078 1.43e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KODCOHLO_01079 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
KODCOHLO_01080 1.34e-256 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KODCOHLO_01081 1.55e-274 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
KODCOHLO_01082 7.04e-173 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KODCOHLO_01083 2.99e-289 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KODCOHLO_01084 1.23e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KODCOHLO_01085 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
KODCOHLO_01086 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
KODCOHLO_01087 1.02e-95 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KODCOHLO_01088 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
KODCOHLO_01089 1.24e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KODCOHLO_01090 5.08e-197 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
KODCOHLO_01091 1.49e-11 - - - - - - - -
KODCOHLO_01092 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
KODCOHLO_01093 6.17e-104 ipi - - S - - - Intracellular proteinase inhibitor
KODCOHLO_01094 6.56e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KODCOHLO_01095 1.77e-199 yitS - - S - - - protein conserved in bacteria
KODCOHLO_01097 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KODCOHLO_01098 6.98e-218 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
KODCOHLO_01099 4.36e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
KODCOHLO_01100 3.69e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
KODCOHLO_01101 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KODCOHLO_01102 1.54e-105 - - - S - - - Acetyltransferase (GNAT) domain
KODCOHLO_01103 4.53e-110 yisX - - S - - - Pentapeptide repeats (9 copies)
KODCOHLO_01104 5.99e-105 yisT - - S - - - DinB family
KODCOHLO_01105 9.41e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
KODCOHLO_01106 4.97e-182 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KODCOHLO_01107 1.16e-206 yisR - - K - - - Transcriptional regulator
KODCOHLO_01108 1.24e-311 yisQ - - V - - - Mate efflux family protein
KODCOHLO_01109 4.09e-166 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
KODCOHLO_01110 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KODCOHLO_01111 1.86e-124 yisN - - S - - - Protein of unknown function (DUF2777)
KODCOHLO_01112 6.36e-78 yisL - - S - - - UPF0344 protein
KODCOHLO_01113 5.16e-217 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KODCOHLO_01114 1.03e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
KODCOHLO_01115 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
KODCOHLO_01116 3.82e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
KODCOHLO_01117 6.98e-108 gerPC - - S ko:K06301 - ko00000 Spore germination protein
KODCOHLO_01118 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
KODCOHLO_01119 1.61e-84 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
KODCOHLO_01120 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
KODCOHLO_01121 2.64e-67 yisB - - V - - - COG1403 Restriction endonuclease
KODCOHLO_01122 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
KODCOHLO_01123 1.35e-282 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KODCOHLO_01124 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KODCOHLO_01125 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
KODCOHLO_01126 1.07e-152 ydfS - - S - - - Protein of unknown function (DUF421)
KODCOHLO_01127 1.47e-121 yhjR - - S - - - Rubrerythrin
KODCOHLO_01128 3.71e-140 - - - K - - - QacR-like protein, C-terminal region
KODCOHLO_01129 1.03e-265 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
KODCOHLO_01130 5.69e-261 yhjN - - S ko:K07120 - ko00000 membrane
KODCOHLO_01131 4.89e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
KODCOHLO_01132 0.0 yhjG - - CH - - - FAD binding domain
KODCOHLO_01134 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KODCOHLO_01135 5.48e-143 yhjE - - S - - - SNARE associated Golgi protein
KODCOHLO_01136 4.12e-79 yhjD - - - - - - -
KODCOHLO_01137 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
KODCOHLO_01138 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KODCOHLO_01139 2.64e-63 - - - S - - - Belongs to the UPF0145 family
KODCOHLO_01140 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
KODCOHLO_01141 1.49e-161 yrpD - - S - - - Domain of unknown function, YrpD
KODCOHLO_01142 8.2e-81 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
KODCOHLO_01143 3.48e-86 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
KODCOHLO_01144 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
KODCOHLO_01146 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_01147 7.46e-106 ygaO - - - - - - -
KODCOHLO_01148 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KODCOHLO_01149 4.09e-271 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
KODCOHLO_01150 9.24e-183 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KODCOHLO_01151 1.04e-221 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
KODCOHLO_01152 1.44e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KODCOHLO_01153 2.05e-228 - - - S ko:K07045 - ko00000 Amidohydrolase
KODCOHLO_01154 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KODCOHLO_01155 1.9e-167 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_01156 4.69e-171 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_01157 8.8e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KODCOHLO_01158 4.91e-187 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KODCOHLO_01159 1.91e-292 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
KODCOHLO_01161 0.0 ygaK - - C - - - Berberine and berberine like
KODCOHLO_01162 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KODCOHLO_01163 4.6e-37 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
KODCOHLO_01164 1.9e-116 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
KODCOHLO_01165 1.53e-65 - - - C - - - Na+/H+ antiporter family
KODCOHLO_01166 3.23e-106 - - - C - - - Na+/H+ antiporter family
KODCOHLO_01167 3.29e-248 - - - S - - - AIPR protein
KODCOHLO_01168 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KODCOHLO_01169 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KODCOHLO_01171 4.05e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
KODCOHLO_01172 2.73e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KODCOHLO_01173 2.6e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
KODCOHLO_01174 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KODCOHLO_01175 1.46e-46 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
KODCOHLO_01176 7.03e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
KODCOHLO_01177 4.33e-187 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
KODCOHLO_01178 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
KODCOHLO_01181 8.25e-29 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
KODCOHLO_01182 1.59e-212 ygxA - - S - - - Nucleotidyltransferase-like
KODCOHLO_01183 4.67e-75 ygzB - - S - - - UPF0295 protein
KODCOHLO_01184 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KODCOHLO_01185 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
KODCOHLO_01186 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KODCOHLO_01187 5.27e-239 ygaE - - S - - - Membrane
KODCOHLO_01188 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
KODCOHLO_01189 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KODCOHLO_01190 1.4e-49 ygaB - - S - - - YgaB-like protein
KODCOHLO_01191 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
KODCOHLO_01192 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KODCOHLO_01193 2.87e-47 yfhS - - - - - - -
KODCOHLO_01194 1.64e-261 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
KODCOHLO_01195 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
KODCOHLO_01196 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
KODCOHLO_01197 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KODCOHLO_01198 2.28e-217 - - - S - - - Alpha/beta hydrolase family
KODCOHLO_01199 6.03e-57 yfhL - - S - - - SdpI/YhfL protein family
KODCOHLO_01200 1.91e-120 yfhK - - T - - - Bacterial SH3 domain homologues
KODCOHLO_01201 2.57e-59 yfhJ - - S - - - WVELL protein
KODCOHLO_01202 2.02e-215 mpr - - M - - - Belongs to the peptidase S1B family
KODCOHLO_01204 2.25e-265 yfhI - - EGP - - - -transporter
KODCOHLO_01205 3.1e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
KODCOHLO_01206 5.21e-182 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
KODCOHLO_01207 4.06e-213 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
KODCOHLO_01209 3.61e-34 yfhD - - S - - - YfhD-like protein
KODCOHLO_01210 8.22e-138 yfhC - - C - - - nitroreductase
KODCOHLO_01211 6.68e-205 yfhB - - S - - - PhzF family
KODCOHLO_01212 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KODCOHLO_01213 3.8e-106 yfiV - - K - - - transcriptional
KODCOHLO_01214 0.0 yfiU - - EGP - - - the major facilitator superfamily
KODCOHLO_01215 6.35e-126 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
KODCOHLO_01216 1.66e-60 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
KODCOHLO_01217 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
KODCOHLO_01218 3.49e-232 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KODCOHLO_01219 3.47e-142 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KODCOHLO_01220 4.62e-125 padR - - K - - - transcriptional
KODCOHLO_01221 4.69e-211 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KODCOHLO_01222 1.58e-203 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
KODCOHLO_01223 7.86e-82 yfiD3 - - S - - - DoxX
KODCOHLO_01224 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KODCOHLO_01225 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
KODCOHLO_01226 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KODCOHLO_01227 4.47e-178 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
KODCOHLO_01228 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KODCOHLO_01229 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
KODCOHLO_01230 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
KODCOHLO_01231 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KODCOHLO_01232 3.79e-272 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KODCOHLO_01233 1.34e-239 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KODCOHLO_01234 1.31e-242 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KODCOHLO_01235 3.05e-113 yfjM - - S - - - Psort location Cytoplasmic, score
KODCOHLO_01236 4.22e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KODCOHLO_01237 5.03e-60 - - - S - - - YfzA-like protein
KODCOHLO_01238 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KODCOHLO_01239 1.21e-208 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KODCOHLO_01240 2.61e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
KODCOHLO_01242 2.98e-188 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KODCOHLO_01243 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
KODCOHLO_01244 7.99e-37 yfjT - - - - - - -
KODCOHLO_01245 4.65e-279 yfkA - - S - - - YfkB-like domain
KODCOHLO_01246 2.37e-185 yfkC - - M - - - Mechanosensitive ion channel
KODCOHLO_01247 1.33e-184 yfkD - - S - - - YfkD-like protein
KODCOHLO_01248 3.43e-238 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
KODCOHLO_01249 1.39e-276 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KODCOHLO_01250 6.71e-12 - - - - - - - -
KODCOHLO_01251 1.6e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KODCOHLO_01252 2.14e-69 yfkI - - S - - - gas vesicle protein
KODCOHLO_01253 6.88e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KODCOHLO_01254 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
KODCOHLO_01255 3.85e-249 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KODCOHLO_01256 2.04e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KODCOHLO_01257 4.07e-215 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KODCOHLO_01258 1.51e-237 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KODCOHLO_01259 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KODCOHLO_01260 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
KODCOHLO_01263 1.16e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
KODCOHLO_01265 6.38e-71 - - - S - - - Protein of unknown function (DUF1064)
KODCOHLO_01266 6.31e-14 - - - S - - - YopX protein
KODCOHLO_01268 4.91e-71 - - - L ko:K02315 - ko00000,ko03032 Bacterial dnaA protein
KODCOHLO_01270 1.07e-158 recT - - L ko:K07455 - ko00000,ko03400 RecT family
KODCOHLO_01271 1.89e-193 yqaJ - - L - - - YqaJ-like viral recombinase domain
KODCOHLO_01276 1.06e-99 - - - - - - - -
KODCOHLO_01277 3.26e-39 - - - S - - - DNA binding
KODCOHLO_01279 1.66e-17 - - - K - - - Helix-turn-helix XRE-family like proteins
KODCOHLO_01280 1.68e-30 - - - K ko:K07467 - ko00000 sequence-specific DNA binding
KODCOHLO_01281 1e-06 - - - - - - - -
KODCOHLO_01282 3.4e-35 xkdA - - E - - - IrrE N-terminal-like domain
KODCOHLO_01283 4.14e-25 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_01284 2.19e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
KODCOHLO_01285 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KODCOHLO_01286 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KODCOHLO_01287 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
KODCOHLO_01288 7.02e-103 yslB - - S - - - Protein of unknown function (DUF2507)
KODCOHLO_01289 1.43e-273 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KODCOHLO_01290 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KODCOHLO_01291 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KODCOHLO_01292 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
KODCOHLO_01293 1.18e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
KODCOHLO_01294 1.01e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
KODCOHLO_01295 1.43e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
KODCOHLO_01296 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_01297 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KODCOHLO_01298 5.29e-64 ywbB - - S - - - Protein of unknown function (DUF2711)
KODCOHLO_01299 3.38e-61 ywbB - - S - - - Protein of unknown function (DUF2711)
KODCOHLO_01300 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
KODCOHLO_01301 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KODCOHLO_01302 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
KODCOHLO_01303 1.42e-107 yshB - - S - - - membrane protein, required for colicin V production
KODCOHLO_01304 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KODCOHLO_01305 7.57e-216 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KODCOHLO_01306 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KODCOHLO_01307 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KODCOHLO_01308 4.63e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KODCOHLO_01309 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
KODCOHLO_01310 2.81e-258 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
KODCOHLO_01311 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
KODCOHLO_01312 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
KODCOHLO_01313 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
KODCOHLO_01314 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
KODCOHLO_01315 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
KODCOHLO_01316 1.78e-214 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
KODCOHLO_01317 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
KODCOHLO_01318 3.19e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KODCOHLO_01319 1.02e-179 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
KODCOHLO_01320 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KODCOHLO_01321 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
KODCOHLO_01322 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
KODCOHLO_01323 8.14e-240 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
KODCOHLO_01324 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
KODCOHLO_01325 3.13e-86 ysdB - - S - - - Sigma-w pathway protein YsdB
KODCOHLO_01326 5.44e-56 ysdA - - S - - - Membrane
KODCOHLO_01327 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KODCOHLO_01328 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KODCOHLO_01329 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KODCOHLO_01330 2.09e-145 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KODCOHLO_01331 7.85e-67 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
KODCOHLO_01332 8.61e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
KODCOHLO_01333 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_01334 6.92e-192 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
KODCOHLO_01335 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KODCOHLO_01336 1.63e-196 ytxC - - S - - - YtxC-like family
KODCOHLO_01337 4.27e-138 ytxB - - S - - - SNARE associated Golgi protein
KODCOHLO_01338 4.08e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KODCOHLO_01339 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
KODCOHLO_01340 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KODCOHLO_01341 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KODCOHLO_01342 2.1e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KODCOHLO_01343 1.69e-89 ytcD - - K - - - Transcriptional regulator
KODCOHLO_01344 6.86e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
KODCOHLO_01345 3.74e-204 ytbE - - S - - - reductase
KODCOHLO_01346 4.17e-128 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KODCOHLO_01347 5.73e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
KODCOHLO_01348 2.32e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KODCOHLO_01349 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KODCOHLO_01350 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
KODCOHLO_01351 2.9e-167 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KODCOHLO_01352 1.48e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
KODCOHLO_01353 5.36e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
KODCOHLO_01354 2.86e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KODCOHLO_01355 1.24e-79 yjdF3 - - S - - - Protein of unknown function (DUF2992)
KODCOHLO_01356 5.65e-96 ytwI - - S - - - membrane
KODCOHLO_01357 1.65e-246 ytvI - - S - - - sporulation integral membrane protein YtvI
KODCOHLO_01358 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
KODCOHLO_01359 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KODCOHLO_01360 2.39e-218 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KODCOHLO_01361 1.67e-288 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_01364 4.87e-234 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KODCOHLO_01365 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
KODCOHLO_01366 2.3e-159 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
KODCOHLO_01367 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KODCOHLO_01368 3.6e-242 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KODCOHLO_01369 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
KODCOHLO_01370 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KODCOHLO_01371 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KODCOHLO_01372 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KODCOHLO_01373 3.33e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KODCOHLO_01374 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
KODCOHLO_01375 8.26e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
KODCOHLO_01376 1.24e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KODCOHLO_01377 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KODCOHLO_01378 3.3e-63 - - - - - - - -
KODCOHLO_01379 7.82e-201 - - - S - - - Bacterial EndoU nuclease
KODCOHLO_01380 1.94e-104 - - - V - - - Type I restriction modification DNA specificity domain
KODCOHLO_01381 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
KODCOHLO_01382 3.33e-136 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
KODCOHLO_01383 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KODCOHLO_01384 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
KODCOHLO_01385 2.05e-256 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
KODCOHLO_01386 6.9e-315 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
KODCOHLO_01387 8.2e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
KODCOHLO_01388 2.09e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
KODCOHLO_01389 3.9e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
KODCOHLO_01390 2.57e-228 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KODCOHLO_01391 2.5e-159 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
KODCOHLO_01392 3.98e-201 ydjI - - S - - - virion core protein (lumpy skin disease virus)
KODCOHLO_01393 0.0 oatA - - I - - - Acyltransferase family
KODCOHLO_01394 1.96e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
KODCOHLO_01395 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KODCOHLO_01396 8.25e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
KODCOHLO_01397 6.51e-82 ydjM - - M - - - Lytic transglycolase
KODCOHLO_01398 4.75e-193 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
KODCOHLO_01400 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
KODCOHLO_01401 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
KODCOHLO_01402 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KODCOHLO_01403 4.43e-223 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
KODCOHLO_01404 4.16e-264 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KODCOHLO_01405 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
KODCOHLO_01406 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KODCOHLO_01407 4.67e-122 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KODCOHLO_01408 2.61e-314 - - - S - - - Domain of unknown function (DUF4179)
KODCOHLO_01409 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KODCOHLO_01410 6.19e-168 yebC - - M - - - Membrane
KODCOHLO_01412 1.21e-118 yebE - - S - - - UPF0316 protein
KODCOHLO_01413 6.56e-40 yebG - - S - - - NETI protein
KODCOHLO_01414 3.78e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KODCOHLO_01415 3.74e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KODCOHLO_01416 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KODCOHLO_01417 3.96e-165 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KODCOHLO_01418 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KODCOHLO_01419 1.34e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KODCOHLO_01420 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KODCOHLO_01421 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KODCOHLO_01422 1.46e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KODCOHLO_01423 9.96e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KODCOHLO_01424 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KODCOHLO_01425 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KODCOHLO_01426 1.2e-33 - - - S - - - Protein of unknown function (DUF2892)
KODCOHLO_01427 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
KODCOHLO_01428 4.95e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
KODCOHLO_01429 2.03e-67 yerC - - S - - - protein conserved in bacteria
KODCOHLO_01430 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
KODCOHLO_01431 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KODCOHLO_01432 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KODCOHLO_01433 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KODCOHLO_01434 6.46e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
KODCOHLO_01435 9.58e-244 yerI - - S - - - homoserine kinase type II (protein kinase fold)
KODCOHLO_01436 1.68e-157 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
KODCOHLO_01437 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KODCOHLO_01438 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KODCOHLO_01439 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KODCOHLO_01440 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KODCOHLO_01441 5.24e-196 yerO - - K - - - Transcriptional regulator
KODCOHLO_01442 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KODCOHLO_01443 5.16e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KODCOHLO_01444 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KODCOHLO_01445 5.4e-28 - - - - - - - -
KODCOHLO_01446 9.62e-203 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KODCOHLO_01447 3.36e-176 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
KODCOHLO_01448 6.42e-50 - - - S - - - Protein of unknown function, DUF600
KODCOHLO_01449 1.27e-109 - - - S - - - Protein of unknown function, DUF600
KODCOHLO_01450 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
KODCOHLO_01451 2.73e-27 - - - - - - - -
KODCOHLO_01452 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
KODCOHLO_01454 9.27e-137 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
KODCOHLO_01455 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
KODCOHLO_01456 9.4e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
KODCOHLO_01457 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
KODCOHLO_01458 4.48e-120 yesJ - - K - - - Acetyltransferase (GNAT) family
KODCOHLO_01459 8.36e-05 - - - - - - - -
KODCOHLO_01460 8.62e-155 yetF - - S - - - membrane
KODCOHLO_01461 6.42e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
KODCOHLO_01462 2.66e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KODCOHLO_01463 3.63e-196 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KODCOHLO_01464 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
KODCOHLO_01465 3.68e-73 - - - H - - - riboflavin kinase activity
KODCOHLO_01466 3.11e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
KODCOHLO_01468 1.92e-113 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
KODCOHLO_01469 3.88e-261 yetM - - CH - - - FAD binding domain
KODCOHLO_01470 2.38e-252 yetN - - S - - - Protein of unknown function (DUF3900)
KODCOHLO_01471 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
KODCOHLO_01472 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KODCOHLO_01473 1.02e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
KODCOHLO_01474 3.93e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
KODCOHLO_01475 6.61e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
KODCOHLO_01476 4.01e-282 yfnE - - S - - - Glycosyltransferase like family 2
KODCOHLO_01477 3.31e-237 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
KODCOHLO_01478 6.35e-277 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KODCOHLO_01479 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
KODCOHLO_01480 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KODCOHLO_01481 2.04e-162 yfmS - - NT - - - chemotaxis protein
KODCOHLO_01482 8.54e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KODCOHLO_01483 3.45e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
KODCOHLO_01484 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KODCOHLO_01485 8.7e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
KODCOHLO_01486 3.43e-262 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
KODCOHLO_01487 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KODCOHLO_01488 2.83e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
KODCOHLO_01489 1.86e-55 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
KODCOHLO_01490 5.49e-238 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
KODCOHLO_01491 7.35e-32 - - - S - - - Protein of unknown function (DUF3212)
KODCOHLO_01492 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
KODCOHLO_01493 7.93e-309 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
KODCOHLO_01494 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KODCOHLO_01497 1.91e-286 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_01498 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
KODCOHLO_01499 6.15e-180 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
KODCOHLO_01500 2.48e-315 - - - E - - - Aminotransferase class I and II
KODCOHLO_01501 1.25e-165 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
KODCOHLO_01502 4.07e-140 yczE - - S ko:K07149 - ko00000 membrane
KODCOHLO_01503 2.28e-168 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KODCOHLO_01504 3.03e-154 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KODCOHLO_01505 1.14e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KODCOHLO_01506 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
KODCOHLO_01507 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KODCOHLO_01508 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KODCOHLO_01509 4.71e-51 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
KODCOHLO_01510 9.68e-100 yclD - - - - - - -
KODCOHLO_01511 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
KODCOHLO_01512 0.0 yclG - - M - - - Pectate lyase superfamily protein
KODCOHLO_01514 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
KODCOHLO_01515 2.31e-299 gerKC - - S ko:K06297 - ko00000 spore germination
KODCOHLO_01516 2.27e-249 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
KODCOHLO_01517 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KODCOHLO_01518 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KODCOHLO_01519 1.43e-179 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KODCOHLO_01520 2.11e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KODCOHLO_01521 5.6e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_01522 1.97e-276 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
KODCOHLO_01523 4.55e-315 yxeQ - - S - - - MmgE/PrpD family
KODCOHLO_01524 3.66e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KODCOHLO_01525 1e-308 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
KODCOHLO_01526 1.06e-163 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KODCOHLO_01527 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
KODCOHLO_01528 6.79e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KODCOHLO_01530 2.47e-315 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KODCOHLO_01531 1.1e-210 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KODCOHLO_01532 1.64e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KODCOHLO_01533 1.33e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_01534 5.37e-221 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
KODCOHLO_01535 9.81e-314 ycnB - - EGP - - - the major facilitator superfamily
KODCOHLO_01536 1.23e-194 ycnC - - K - - - Transcriptional regulator
KODCOHLO_01537 1.38e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
KODCOHLO_01538 1.97e-59 ycnE - - S - - - Monooxygenase
KODCOHLO_01539 3.92e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KODCOHLO_01540 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KODCOHLO_01541 1.4e-283 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KODCOHLO_01542 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KODCOHLO_01543 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
KODCOHLO_01544 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KODCOHLO_01545 3.4e-130 ycnI - - S - - - protein conserved in bacteria
KODCOHLO_01546 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
KODCOHLO_01547 1.74e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KODCOHLO_01548 9.6e-73 - - - - - - - -
KODCOHLO_01549 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
KODCOHLO_01550 2.38e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KODCOHLO_01551 2.72e-262 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
KODCOHLO_01552 2.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
KODCOHLO_01554 2.69e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
KODCOHLO_01555 7.14e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
KODCOHLO_01556 7.29e-269 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
KODCOHLO_01557 2.41e-192 ycsI - - S - - - Belongs to the D-glutamate cyclase family
KODCOHLO_01558 6.36e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
KODCOHLO_01559 5.72e-239 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
KODCOHLO_01560 4.65e-167 kipR - - K - - - Transcriptional regulator
KODCOHLO_01561 1.52e-147 ycsK - - E - - - anatomical structure formation involved in morphogenesis
KODCOHLO_01563 5.95e-75 yczJ - - S - - - biosynthesis
KODCOHLO_01564 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
KODCOHLO_01565 4.09e-218 ycsN - - S - - - Oxidoreductase
KODCOHLO_01566 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
KODCOHLO_01567 0.0 ydaB - - IQ - - - acyl-CoA ligase
KODCOHLO_01568 5.2e-205 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KODCOHLO_01569 3.22e-124 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
KODCOHLO_01570 4.04e-149 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KODCOHLO_01571 1.83e-101 ydaG - - S - - - general stress protein
KODCOHLO_01572 7.59e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KODCOHLO_01573 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
KODCOHLO_01574 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KODCOHLO_01575 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KODCOHLO_01576 5.44e-256 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
KODCOHLO_01577 3.12e-188 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
KODCOHLO_01578 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
KODCOHLO_01579 1.85e-302 ydaM - - M - - - Glycosyl transferase family group 2
KODCOHLO_01580 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
KODCOHLO_01581 0.0 ydaO - - E - - - amino acid
KODCOHLO_01582 1.16e-92 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KODCOHLO_01583 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KODCOHLO_01584 1.81e-17 - - - - - - - -
KODCOHLO_01586 9.87e-112 - - - - - - - -
KODCOHLO_01587 5.14e-131 - - - - - - - -
KODCOHLO_01588 7.18e-52 - - - - - - - -
KODCOHLO_01589 5.35e-288 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KODCOHLO_01592 1.13e-44 ydaT - - - - - - -
KODCOHLO_01593 5.53e-96 yvaD - - S - - - Family of unknown function (DUF5360)
KODCOHLO_01594 2.87e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
KODCOHLO_01595 1.04e-179 ydbA - - P - - - EcsC protein family
KODCOHLO_01596 2.53e-159 - - - S - - - amine dehydrogenase activity
KODCOHLO_01599 3.09e-266 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KODCOHLO_01600 1.34e-231 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KODCOHLO_01601 3.59e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KODCOHLO_01602 2.45e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KODCOHLO_01603 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KODCOHLO_01604 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
KODCOHLO_01605 4.38e-113 ytrI - - - - - - -
KODCOHLO_01606 1e-31 - - - - - - - -
KODCOHLO_01607 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
KODCOHLO_01608 3.57e-62 ytpI - - S - - - YtpI-like protein
KODCOHLO_01609 1.31e-302 ytoI - - K - - - transcriptional regulator containing CBS domains
KODCOHLO_01610 4.86e-165 ytkL - - S - - - Belongs to the UPF0173 family
KODCOHLO_01611 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KODCOHLO_01613 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KODCOHLO_01614 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KODCOHLO_01615 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
KODCOHLO_01616 1.57e-279 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KODCOHLO_01617 1.69e-231 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
KODCOHLO_01618 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KODCOHLO_01619 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
KODCOHLO_01620 1.26e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
KODCOHLO_01621 2.77e-114 yteJ - - S - - - RDD family
KODCOHLO_01622 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
KODCOHLO_01623 3.16e-194 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KODCOHLO_01624 0.0 ytcJ - - S - - - amidohydrolase
KODCOHLO_01625 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KODCOHLO_01626 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
KODCOHLO_01627 2.01e-285 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KODCOHLO_01628 1.85e-264 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KODCOHLO_01629 1.32e-306 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KODCOHLO_01630 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KODCOHLO_01631 1.46e-196 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KODCOHLO_01632 2.41e-141 yttP - - K - - - Transcriptional regulator
KODCOHLO_01633 2.48e-111 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KODCOHLO_01634 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
KODCOHLO_01635 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KODCOHLO_01636 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KODCOHLO_01637 1.38e-127 yokH - - G - - - SMI1 / KNR4 family
KODCOHLO_01638 6.9e-279 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KODCOHLO_01640 1.93e-117 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KODCOHLO_01642 4.63e-174 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KODCOHLO_01643 3.37e-191 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KODCOHLO_01644 1.29e-189 - - - K - - - Transcriptional regulator
KODCOHLO_01645 9.98e-161 ygaZ - - E - - - AzlC protein
KODCOHLO_01646 2.07e-62 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
KODCOHLO_01647 3.46e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KODCOHLO_01648 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KODCOHLO_01649 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KODCOHLO_01650 1.19e-149 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
KODCOHLO_01651 5.32e-288 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
KODCOHLO_01652 4.27e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KODCOHLO_01653 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KODCOHLO_01654 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KODCOHLO_01655 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KODCOHLO_01656 5.67e-56 ytxJ - - O - - - Protein of unknown function (DUF2847)
KODCOHLO_01657 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
KODCOHLO_01658 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KODCOHLO_01659 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KODCOHLO_01660 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KODCOHLO_01661 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KODCOHLO_01662 3.98e-189 ytpQ - - S - - - Belongs to the UPF0354 family
KODCOHLO_01663 5.47e-76 ytpP - - CO - - - Thioredoxin
KODCOHLO_01664 3.91e-100 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
KODCOHLO_01665 4.33e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
KODCOHLO_01666 9.96e-69 ytzB - - S - - - small secreted protein
KODCOHLO_01667 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KODCOHLO_01668 5.98e-206 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KODCOHLO_01669 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KODCOHLO_01670 3.88e-60 ytzH - - S - - - YtzH-like protein
KODCOHLO_01671 2.93e-199 ytmP - - M - - - Phosphotransferase
KODCOHLO_01672 4.62e-224 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KODCOHLO_01673 4.18e-211 ytlQ - - - - - - -
KODCOHLO_01674 6.34e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KODCOHLO_01675 6.81e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KODCOHLO_01676 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
KODCOHLO_01677 1.42e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
KODCOHLO_01678 2.04e-275 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
KODCOHLO_01679 1.56e-164 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KODCOHLO_01680 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
KODCOHLO_01681 8.33e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KODCOHLO_01682 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KODCOHLO_01683 5.3e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
KODCOHLO_01684 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
KODCOHLO_01685 2.14e-36 yteV - - S - - - Sporulation protein Cse60
KODCOHLO_01686 1.29e-237 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_01687 4.42e-308 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KODCOHLO_01688 5.58e-218 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KODCOHLO_01689 6.79e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KODCOHLO_01690 9.62e-317 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
KODCOHLO_01691 1.98e-110 - - - M - - - Acetyltransferase (GNAT) domain
KODCOHLO_01692 6.05e-69 ytwF - - P - - - Sulfurtransferase
KODCOHLO_01693 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KODCOHLO_01694 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
KODCOHLO_01695 1.32e-174 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KODCOHLO_01696 6.76e-269 yttB - - EGP - - - Major facilitator superfamily
KODCOHLO_01697 8.49e-157 ywaF - - S - - - Integral membrane protein
KODCOHLO_01698 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
KODCOHLO_01699 2.2e-172 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_01700 6.12e-222 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
KODCOHLO_01701 4.49e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KODCOHLO_01702 3.9e-287 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KODCOHLO_01703 3.01e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_01704 6.73e-203 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
KODCOHLO_01705 1.19e-231 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KODCOHLO_01706 6.39e-215 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KODCOHLO_01707 5.11e-208 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_01708 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
KODCOHLO_01710 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
KODCOHLO_01711 0.0 - - - IQ - - - AMP-binding enzyme
KODCOHLO_01712 0.0 - - - Q ko:K15654 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 TIGRFAM amino acid adenylation domain
KODCOHLO_01713 7.23e-148 - 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 PFAM Acyl transferase
KODCOHLO_01714 0.0 - - - Q ko:K13614 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
KODCOHLO_01715 0.0 - - - Q - - - Polyketide synthase modules and related proteins
KODCOHLO_01716 7.24e-121 - - - Q - - - Flavin containing amine oxidoreductase
KODCOHLO_01717 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
KODCOHLO_01718 2.35e-50 - - - Q - - - Dimerisation domain
KODCOHLO_01719 6.33e-104 - - - S - - - Domain of unknown function (DUF4879)
KODCOHLO_01720 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
KODCOHLO_01721 2.06e-143 yqeB - - - - - - -
KODCOHLO_01722 7.84e-55 ybyB - - - - - - -
KODCOHLO_01723 0.0 ybeC - - E - - - amino acid
KODCOHLO_01724 4.93e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
KODCOHLO_01725 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
KODCOHLO_01726 4.08e-23 - - - S - - - Protein of unknown function (DUF2651)
KODCOHLO_01727 1.36e-265 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
KODCOHLO_01729 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
KODCOHLO_01730 1.05e-46 - - - - - - - -
KODCOHLO_01731 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
KODCOHLO_01732 4.61e-250 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
KODCOHLO_01733 6.53e-271 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KODCOHLO_01734 3.15e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KODCOHLO_01735 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
KODCOHLO_01736 1.45e-192 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KODCOHLO_01737 1.5e-55 ybfN - - - - - - -
KODCOHLO_01738 9.56e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
KODCOHLO_01739 1.59e-269 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KODCOHLO_01740 8.33e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KODCOHLO_01741 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KODCOHLO_01742 2.4e-229 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
KODCOHLO_01743 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
KODCOHLO_01744 1.25e-237 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KODCOHLO_01745 7.42e-271 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_01746 4.77e-220 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
KODCOHLO_01747 1.96e-157 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
KODCOHLO_01748 2.81e-34 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
KODCOHLO_01749 7.1e-197 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KODCOHLO_01750 1.57e-141 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
KODCOHLO_01751 4.33e-235 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KODCOHLO_01752 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
KODCOHLO_01753 5.37e-74 ydfQ - - CO - - - Thioredoxin
KODCOHLO_01754 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
KODCOHLO_01755 1.75e-100 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
KODCOHLO_01756 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
KODCOHLO_01757 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KODCOHLO_01758 7.24e-155 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KODCOHLO_01759 9.45e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KODCOHLO_01760 8.74e-260 ycbU - - E - - - Selenocysteine lyase
KODCOHLO_01761 4.82e-311 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
KODCOHLO_01762 1.48e-128 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KODCOHLO_01763 4.05e-247 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KODCOHLO_01764 8.07e-148 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
KODCOHLO_01765 1.61e-250 yccF - - K ko:K07039 - ko00000 SEC-C motif
KODCOHLO_01766 3.62e-217 yccK - - C - - - Aldo keto reductase
KODCOHLO_01767 2.66e-225 ycdA - - S - - - Domain of unknown function (DUF5105)
KODCOHLO_01768 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KODCOHLO_01769 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KODCOHLO_01770 1.72e-119 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KODCOHLO_01771 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
KODCOHLO_01772 4.28e-179 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
KODCOHLO_01773 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KODCOHLO_01774 1.41e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KODCOHLO_01775 1.4e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KODCOHLO_01776 6.86e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KODCOHLO_01777 1.07e-22 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KODCOHLO_01778 1.16e-151 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KODCOHLO_01779 4.06e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
KODCOHLO_01780 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
KODCOHLO_01781 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
KODCOHLO_01782 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
KODCOHLO_01783 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
KODCOHLO_01784 1.17e-246 yceH - - P - - - Belongs to the TelA family
KODCOHLO_01785 6.09e-275 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
KODCOHLO_01786 7.71e-294 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
KODCOHLO_01787 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KODCOHLO_01788 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KODCOHLO_01789 3.1e-268 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
KODCOHLO_01790 1.8e-290 ycgA - - S - - - Membrane
KODCOHLO_01791 2.55e-105 ycgB - - - - - - -
KODCOHLO_01792 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
KODCOHLO_01793 1.09e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KODCOHLO_01794 0.0 mdr - - EGP - - - the major facilitator superfamily
KODCOHLO_01795 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
KODCOHLO_01796 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
KODCOHLO_01797 1.71e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
KODCOHLO_01798 3.84e-313 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KODCOHLO_01799 1.31e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
KODCOHLO_01800 1.29e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KODCOHLO_01801 6.96e-07 - - - S - - - Bacillus cereus group antimicrobial protein
KODCOHLO_01802 1.85e-138 tmrB - - S - - - AAA domain
KODCOHLO_01803 2.22e-187 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
KODCOHLO_01804 1.66e-288 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KODCOHLO_01805 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KODCOHLO_01806 1.63e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
KODCOHLO_01807 1.06e-189 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
KODCOHLO_01808 9.21e-215 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KODCOHLO_01809 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KODCOHLO_01810 7.72e-312 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KODCOHLO_01811 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
KODCOHLO_01812 1.58e-240 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KODCOHLO_01813 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KODCOHLO_01814 5.73e-73 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
KODCOHLO_01815 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KODCOHLO_01816 3.21e-286 yciC - - S - - - GTPases (G3E family)
KODCOHLO_01817 1.02e-280 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KODCOHLO_01818 1.32e-94 yckC - - S - - - membrane
KODCOHLO_01819 5.94e-64 - - - S - - - Protein of unknown function (DUF2680)
KODCOHLO_01820 1.58e-13 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KODCOHLO_01821 1.27e-86 nin - - S - - - Competence protein J (ComJ)
KODCOHLO_01822 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
KODCOHLO_01823 1.54e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
KODCOHLO_01824 4.28e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
KODCOHLO_01825 1.38e-82 hxlR - - K - - - transcriptional
KODCOHLO_01828 3.34e-210 yraN - - K - - - Transcriptional regulator
KODCOHLO_01829 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KODCOHLO_01830 1.51e-232 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
KODCOHLO_01831 2.24e-282 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
KODCOHLO_01832 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KODCOHLO_01834 1.31e-45 - - - - - - - -
KODCOHLO_01835 0.0 - - - I - - - Pfam Lipase (class 3)
KODCOHLO_01836 5.62e-16 - - - S - - - Protein of unknown function (DUF1433)
KODCOHLO_01838 2.86e-18 - - - S - - - Protein of unknown function (DUF1433)
KODCOHLO_01839 7.09e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
KODCOHLO_01840 7.44e-117 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KODCOHLO_01841 4.34e-145 yyaS - - S ko:K07149 - ko00000 Membrane
KODCOHLO_01842 1.91e-125 ywjB - - H - - - RibD C-terminal domain
KODCOHLO_01843 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
KODCOHLO_01844 6.96e-100 - - - K ko:K19417 - ko00000,ko03000 transcriptional
KODCOHLO_01845 7.89e-154 epsA - - M ko:K19420 - ko00000 biosynthesis protein
KODCOHLO_01846 3.12e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KODCOHLO_01847 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KODCOHLO_01848 1.13e-273 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
KODCOHLO_01849 1.85e-204 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
KODCOHLO_01850 1.17e-270 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KODCOHLO_01851 4.69e-260 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
KODCOHLO_01852 3.62e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
KODCOHLO_01853 8.08e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
KODCOHLO_01854 3e-249 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KODCOHLO_01855 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KODCOHLO_01856 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KODCOHLO_01857 2.23e-71 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KODCOHLO_01858 2.61e-280 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
KODCOHLO_01859 3.71e-236 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
KODCOHLO_01860 4.01e-44 yvfG - - S - - - YvfG protein
KODCOHLO_01861 1.32e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KODCOHLO_01862 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KODCOHLO_01863 2.55e-155 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
KODCOHLO_01864 1.39e-278 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KODCOHLO_01865 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KODCOHLO_01866 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KODCOHLO_01867 9.73e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KODCOHLO_01868 1.6e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
KODCOHLO_01869 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KODCOHLO_01870 7.4e-193 gntR - - K - - - RpiR family transcriptional regulator
KODCOHLO_01871 1.65e-210 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KODCOHLO_01872 1.81e-148 - - - S ko:K07149 - ko00000 Membrane
KODCOHLO_01873 3.7e-233 yhjM - - K - - - Transcriptional regulator
KODCOHLO_01874 0.0 - - - - - - - -
KODCOHLO_01875 9.5e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KODCOHLO_01876 5.22e-203 yvbV - - EG - - - EamA-like transporter family
KODCOHLO_01877 4.32e-200 yvbU - - K - - - Transcriptional regulator
KODCOHLO_01879 7.57e-243 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KODCOHLO_01880 2.23e-260 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
KODCOHLO_01881 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KODCOHLO_01883 4.89e-239 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KODCOHLO_01884 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KODCOHLO_01885 9.37e-276 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KODCOHLO_01886 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KODCOHLO_01887 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
KODCOHLO_01888 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KODCOHLO_01889 1.34e-300 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
KODCOHLO_01890 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KODCOHLO_01891 1.89e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
KODCOHLO_01892 2.87e-218 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
KODCOHLO_01893 3.75e-285 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KODCOHLO_01894 4.9e-186 - - - M - - - Protein involved in cellulose biosynthesis
KODCOHLO_01895 4.79e-184 - - - C - - - WbqC-like protein family
KODCOHLO_01896 8.69e-160 - - - S - - - GlcNAc-PI de-N-acetylase
KODCOHLO_01897 2.21e-225 - - - - - - - -
KODCOHLO_01898 2.99e-267 - - - EGP - - - Major facilitator Superfamily
KODCOHLO_01899 1.29e-105 yvbK - - K - - - acetyltransferase
KODCOHLO_01900 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
KODCOHLO_01901 3.1e-156 yvbI - - M - - - Membrane
KODCOHLO_01902 4.44e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
KODCOHLO_01903 2.38e-128 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KODCOHLO_01904 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KODCOHLO_01905 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KODCOHLO_01906 3.25e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KODCOHLO_01907 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KODCOHLO_01908 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KODCOHLO_01909 1.52e-263 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KODCOHLO_01910 2.68e-143 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KODCOHLO_01911 2.99e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KODCOHLO_01912 1.72e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KODCOHLO_01913 2.67e-162 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_01914 2.72e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KODCOHLO_01915 5.78e-169 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KODCOHLO_01916 1.29e-156 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
KODCOHLO_01917 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
KODCOHLO_01918 2.97e-70 yvaP - - K - - - transcriptional
KODCOHLO_01919 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KODCOHLO_01920 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
KODCOHLO_01921 1.64e-47 yvzC - - K - - - transcriptional
KODCOHLO_01922 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
KODCOHLO_01923 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
KODCOHLO_01924 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KODCOHLO_01925 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KODCOHLO_01927 5.51e-162 - - - S - - - Phage integrase family
KODCOHLO_01928 2.33e-83 - - - - - - - -
KODCOHLO_01931 5.98e-33 - - - K - - - Transcriptional
KODCOHLO_01932 1.42e-07 - - - K - - - Helix-turn-helix XRE-family like proteins
KODCOHLO_01935 5.83e-111 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
KODCOHLO_01936 1.57e-279 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
KODCOHLO_01937 5.18e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KODCOHLO_01938 1.44e-226 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
KODCOHLO_01939 2.8e-256 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
KODCOHLO_01940 3.19e-287 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
KODCOHLO_01941 2.09e-220 ybaS - - S - - - Na -dependent transporter
KODCOHLO_01942 1.19e-137 ybbA - - S ko:K07017 - ko00000 Putative esterase
KODCOHLO_01943 2.37e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KODCOHLO_01944 4.42e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KODCOHLO_01945 2.1e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
KODCOHLO_01946 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
KODCOHLO_01947 1.51e-298 ybbC - - S - - - protein conserved in bacteria
KODCOHLO_01948 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
KODCOHLO_01949 3.79e-310 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
KODCOHLO_01950 2.05e-310 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KODCOHLO_01951 3.68e-205 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KODCOHLO_01952 3.4e-108 ybbJ - - J - - - acetyltransferase
KODCOHLO_01953 3.89e-101 ybbK - - S - - - Protein of unknown function (DUF523)
KODCOHLO_01955 1.98e-89 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
KODCOHLO_01956 1.18e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KODCOHLO_01957 9.73e-276 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
KODCOHLO_01958 2.03e-177 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KODCOHLO_01959 1.52e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KODCOHLO_01960 3.52e-293 ylbM - - S - - - Belongs to the UPF0348 family
KODCOHLO_01961 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
KODCOHLO_01962 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KODCOHLO_01963 3.13e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KODCOHLO_01964 4.63e-116 ylbP - - K - - - n-acetyltransferase
KODCOHLO_01965 3.4e-210 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KODCOHLO_01966 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KODCOHLO_01967 9.07e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KODCOHLO_01968 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KODCOHLO_01969 2.4e-68 ftsL - - D - - - Essential cell division protein
KODCOHLO_01970 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KODCOHLO_01971 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
KODCOHLO_01972 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KODCOHLO_01973 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KODCOHLO_01974 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KODCOHLO_01975 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KODCOHLO_01976 5.69e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KODCOHLO_01977 7.87e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
KODCOHLO_01978 1.04e-176 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KODCOHLO_01979 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KODCOHLO_01980 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KODCOHLO_01981 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
KODCOHLO_01982 1.07e-213 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KODCOHLO_01983 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KODCOHLO_01984 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KODCOHLO_01985 2.21e-184 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KODCOHLO_01986 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
KODCOHLO_01987 7.13e-52 ylmC - - S - - - sporulation protein
KODCOHLO_01988 9.55e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
KODCOHLO_01989 1.5e-160 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KODCOHLO_01990 4.61e-85 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KODCOHLO_01991 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
KODCOHLO_01992 3.54e-181 ylmH - - S - - - conserved protein, contains S4-like domain
KODCOHLO_01993 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
KODCOHLO_01994 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KODCOHLO_01995 4.75e-80 ylyA - - T - - - COG1734 DnaK suppressor protein
KODCOHLO_01996 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KODCOHLO_01997 6.24e-215 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KODCOHLO_01998 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KODCOHLO_01999 2.31e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
KODCOHLO_02000 1.41e-211 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KODCOHLO_02001 3.01e-312 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KODCOHLO_02002 6.23e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KODCOHLO_02003 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
KODCOHLO_02004 8.69e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KODCOHLO_02005 3.5e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KODCOHLO_02006 1.74e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KODCOHLO_02007 7.07e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KODCOHLO_02009 4.03e-180 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
KODCOHLO_02010 3.87e-225 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
KODCOHLO_02011 1.77e-283 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
KODCOHLO_02012 9.22e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
KODCOHLO_02013 2.81e-183 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KODCOHLO_02014 9.78e-186 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
KODCOHLO_02015 2.35e-101 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
KODCOHLO_02016 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
KODCOHLO_02017 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
KODCOHLO_02018 2.5e-197 yloC - - S - - - stress-induced protein
KODCOHLO_02019 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
KODCOHLO_02020 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KODCOHLO_02021 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KODCOHLO_02022 1.08e-287 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KODCOHLO_02023 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KODCOHLO_02024 1.18e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KODCOHLO_02025 5.32e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KODCOHLO_02026 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KODCOHLO_02027 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KODCOHLO_02028 4.98e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KODCOHLO_02029 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KODCOHLO_02030 2.53e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KODCOHLO_02031 1.76e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KODCOHLO_02032 1.06e-152 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KODCOHLO_02033 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KODCOHLO_02034 3.65e-78 yloU - - S - - - protein conserved in bacteria
KODCOHLO_02035 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
KODCOHLO_02036 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KODCOHLO_02037 2.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KODCOHLO_02038 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KODCOHLO_02039 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KODCOHLO_02040 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KODCOHLO_02041 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KODCOHLO_02042 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KODCOHLO_02043 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KODCOHLO_02044 1.43e-172 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KODCOHLO_02045 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KODCOHLO_02046 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KODCOHLO_02047 5.87e-180 - - - S - - - Phosphotransferase enzyme family
KODCOHLO_02048 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KODCOHLO_02049 9.92e-302 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KODCOHLO_02050 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KODCOHLO_02051 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KODCOHLO_02052 3.41e-80 ylqD - - S - - - YlqD protein
KODCOHLO_02053 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KODCOHLO_02054 5.67e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KODCOHLO_02055 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KODCOHLO_02056 4.19e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KODCOHLO_02057 6.81e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KODCOHLO_02058 0.0 ylqG - - - - - - -
KODCOHLO_02059 6.94e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
KODCOHLO_02060 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KODCOHLO_02061 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KODCOHLO_02062 1.42e-213 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
KODCOHLO_02063 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KODCOHLO_02064 1.1e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KODCOHLO_02065 8.93e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
KODCOHLO_02066 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KODCOHLO_02067 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KODCOHLO_02068 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KODCOHLO_02069 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KODCOHLO_02070 2.63e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
KODCOHLO_02071 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
KODCOHLO_02072 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
KODCOHLO_02073 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KODCOHLO_02074 2.66e-120 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
KODCOHLO_02075 2.47e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KODCOHLO_02076 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
KODCOHLO_02077 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
KODCOHLO_02078 3e-260 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
KODCOHLO_02079 1.8e-95 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
KODCOHLO_02080 4.62e-178 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
KODCOHLO_02081 6.59e-81 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
KODCOHLO_02082 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KODCOHLO_02083 1.21e-247 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KODCOHLO_02084 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
KODCOHLO_02085 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
KODCOHLO_02086 8.55e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
KODCOHLO_02087 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
KODCOHLO_02088 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
KODCOHLO_02089 1.03e-241 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KODCOHLO_02090 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KODCOHLO_02091 1.47e-245 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
KODCOHLO_02092 7.73e-201 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
KODCOHLO_02093 6.77e-247 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KODCOHLO_02094 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
KODCOHLO_02095 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
KODCOHLO_02096 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KODCOHLO_02097 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KODCOHLO_02098 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KODCOHLO_02099 3.52e-91 ylxL - - - - - - -
KODCOHLO_02100 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KODCOHLO_02101 9.41e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KODCOHLO_02102 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KODCOHLO_02103 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KODCOHLO_02104 9.06e-186 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KODCOHLO_02105 2.2e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KODCOHLO_02106 2.2e-273 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KODCOHLO_02107 4.66e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KODCOHLO_02108 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KODCOHLO_02109 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_02110 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_02111 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
KODCOHLO_02112 7.37e-315 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
KODCOHLO_02113 3.63e-162 - - - T - - - Transcriptional regulatory protein, C terminal
KODCOHLO_02114 9.54e-303 - - - T - - - Histidine kinase
KODCOHLO_02115 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
KODCOHLO_02116 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
KODCOHLO_02117 8.7e-31 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
KODCOHLO_02118 0.0 yndJ - - S - - - YndJ-like protein
KODCOHLO_02119 1.65e-101 - - - S - - - Domain of unknown function (DUF4166)
KODCOHLO_02120 3.31e-198 yndG - - S - - - DoxX-like family
KODCOHLO_02121 5.09e-283 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
KODCOHLO_02122 5.03e-231 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
KODCOHLO_02123 2.79e-189 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KODCOHLO_02124 1.27e-267 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
KODCOHLO_02125 8.74e-146 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
KODCOHLO_02126 8.49e-242 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
KODCOHLO_02127 1.29e-230 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
KODCOHLO_02128 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
KODCOHLO_02129 3.04e-126 rok - - K - - - Repressor of ComK
KODCOHLO_02130 2.82e-215 yknT - - - ko:K06437 - ko00000 -
KODCOHLO_02131 6.72e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KODCOHLO_02132 1.41e-240 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KODCOHLO_02133 7.96e-309 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
KODCOHLO_02134 3.6e-119 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
KODCOHLO_02135 8.37e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
KODCOHLO_02136 3.43e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KODCOHLO_02137 1.89e-139 yknW - - S - - - Yip1 domain
KODCOHLO_02138 4.7e-245 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KODCOHLO_02139 1.96e-156 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_02140 3.47e-268 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
KODCOHLO_02141 1.32e-169 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_02142 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
KODCOHLO_02143 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KODCOHLO_02144 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KODCOHLO_02145 4.3e-49 ykoA - - - - - - -
KODCOHLO_02146 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KODCOHLO_02147 3.46e-211 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KODCOHLO_02148 1.34e-299 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
KODCOHLO_02149 4.47e-18 - - - S - - - Uncharacterized protein YkpC
KODCOHLO_02150 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
KODCOHLO_02151 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
KODCOHLO_02152 1.88e-309 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KODCOHLO_02153 1.19e-193 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
KODCOHLO_02154 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KODCOHLO_02155 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KODCOHLO_02156 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KODCOHLO_02157 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
KODCOHLO_02158 2.5e-186 ykrA - - S - - - hydrolases of the HAD superfamily
KODCOHLO_02159 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KODCOHLO_02160 3.49e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KODCOHLO_02161 5.36e-132 ykyA - - L - - - Putative cell-wall binding lipoprotein
KODCOHLO_02162 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KODCOHLO_02163 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_02164 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
KODCOHLO_02165 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_02166 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_02167 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_02168 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_02169 0.0 - - - IQ - - - Phosphopantetheine attachment site
KODCOHLO_02170 4.54e-265 - - - V - - - Beta-lactamase
KODCOHLO_02171 7.79e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KODCOHLO_02172 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KODCOHLO_02173 8.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KODCOHLO_02174 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KODCOHLO_02175 3.24e-58 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
KODCOHLO_02176 1.28e-185 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
KODCOHLO_02177 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
KODCOHLO_02178 1.9e-56 yktA - - S - - - Belongs to the UPF0223 family
KODCOHLO_02179 1.35e-153 yktB - - S - - - Belongs to the UPF0637 family
KODCOHLO_02180 7.89e-32 ykzI - - - - - - -
KODCOHLO_02181 3.31e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
KODCOHLO_02182 1.53e-107 ykzC - - S - - - Acetyltransferase (GNAT) family
KODCOHLO_02183 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
KODCOHLO_02185 1.85e-55 ylaE - - - - - - -
KODCOHLO_02186 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
KODCOHLO_02187 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KODCOHLO_02188 8.17e-64 - - - S - - - YlaH-like protein
KODCOHLO_02189 1.37e-45 ylaI - - S - - - protein conserved in bacteria
KODCOHLO_02190 1.83e-136 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KODCOHLO_02191 1.05e-310 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
KODCOHLO_02192 7.13e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KODCOHLO_02193 8.95e-222 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KODCOHLO_02194 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
KODCOHLO_02195 2.02e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KODCOHLO_02196 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KODCOHLO_02197 1.41e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KODCOHLO_02198 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KODCOHLO_02199 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KODCOHLO_02200 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KODCOHLO_02201 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KODCOHLO_02202 6.85e-67 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KODCOHLO_02203 3.45e-210 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
KODCOHLO_02204 2.39e-78 ylbA - - S - - - YugN-like family
KODCOHLO_02205 7.89e-95 ylbB - - T - - - COG0517 FOG CBS domain
KODCOHLO_02206 3.26e-254 ylbC - - S - - - protein with SCP PR1 domains
KODCOHLO_02207 1.64e-84 ylbD - - S - - - Putative coat protein
KODCOHLO_02208 1.73e-48 ylbE - - S - - - YlbE-like protein
KODCOHLO_02209 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
KODCOHLO_02210 5.61e-57 ylbG - - S - - - UPF0298 protein
KODCOHLO_02212 1.02e-97 ykuV - - CO - - - thiol-disulfide
KODCOHLO_02213 1.48e-179 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
KODCOHLO_02214 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
KODCOHLO_02215 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KODCOHLO_02216 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KODCOHLO_02217 8.8e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
KODCOHLO_02218 3.33e-211 ykuO - - - - - - -
KODCOHLO_02219 6.36e-117 ykuN - - C ko:K03839 - ko00000 Flavodoxin
KODCOHLO_02220 2.18e-214 ccpC - - K - - - Transcriptional regulator
KODCOHLO_02221 8.55e-99 ykuL - - S - - - CBS domain
KODCOHLO_02222 3.09e-35 ykzF - - S - - - Antirepressor AbbA
KODCOHLO_02223 2.52e-119 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
KODCOHLO_02224 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
KODCOHLO_02225 2.21e-296 ykuI - - T - - - Diguanylate phosphodiesterase
KODCOHLO_02227 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KODCOHLO_02228 7.09e-195 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
KODCOHLO_02229 8.88e-117 ykuD - - S - - - protein conserved in bacteria
KODCOHLO_02230 5.37e-307 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KODCOHLO_02231 5.07e-108 ykyB - - S - - - YkyB-like protein
KODCOHLO_02232 1.93e-213 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
KODCOHLO_02233 6.38e-15 - - - - - - - -
KODCOHLO_02234 1.62e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KODCOHLO_02235 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_02236 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KODCOHLO_02237 2.88e-159 ykwD - - J - - - protein with SCP PR1 domains
KODCOHLO_02238 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KODCOHLO_02239 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KODCOHLO_02240 4.12e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
KODCOHLO_02241 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_02242 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KODCOHLO_02243 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
KODCOHLO_02244 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KODCOHLO_02245 2.78e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
KODCOHLO_02246 6.8e-223 ykvZ - - K - - - Transcriptional regulator
KODCOHLO_02248 1.35e-262 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KODCOHLO_02249 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
KODCOHLO_02250 4.96e-113 stoA - - CO - - - thiol-disulfide
KODCOHLO_02251 7.63e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KODCOHLO_02252 5.92e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
KODCOHLO_02253 2.92e-38 - - - - - - - -
KODCOHLO_02254 5.43e-35 ykvS - - S - - - protein conserved in bacteria
KODCOHLO_02255 2.54e-60 ykvR - - S - - - Protein of unknown function (DUF3219)
KODCOHLO_02256 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KODCOHLO_02257 5.06e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KODCOHLO_02258 1.26e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
KODCOHLO_02259 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KODCOHLO_02260 6.43e-245 - - - - - - - -
KODCOHLO_02261 5.19e-230 ykvI - - S - - - membrane
KODCOHLO_02262 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
KODCOHLO_02263 4.74e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KODCOHLO_02264 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KODCOHLO_02265 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
KODCOHLO_02266 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KODCOHLO_02268 6.12e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KODCOHLO_02269 3.71e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KODCOHLO_02270 2.71e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KODCOHLO_02271 2.62e-287 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KODCOHLO_02272 3.48e-289 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KODCOHLO_02273 1.64e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KODCOHLO_02274 6.71e-285 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KODCOHLO_02275 1.09e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KODCOHLO_02277 1.04e-74 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KODCOHLO_02278 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_02279 1.52e-240 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
KODCOHLO_02280 1.78e-31 ykzE - - - - - - -
KODCOHLO_02281 4.08e-146 - - - S - - - Protein of unknown function (DUF421)
KODCOHLO_02282 3.8e-308 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
KODCOHLO_02283 1.05e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KODCOHLO_02284 1.14e-161 ykrK - - S - - - Domain of unknown function (DUF1836)
KODCOHLO_02285 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
KODCOHLO_02286 2.2e-231 ykrI - - S - - - Anti-sigma factor N-terminus
KODCOHLO_02287 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KODCOHLO_02288 1.38e-171 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KODCOHLO_02289 7.92e-129 ykoX - - S - - - membrane-associated protein
KODCOHLO_02290 3.83e-199 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KODCOHLO_02291 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
KODCOHLO_02292 1.09e-128 ykoP - - G - - - polysaccharide deacetylase
KODCOHLO_02293 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
KODCOHLO_02294 5.25e-37 ykoL - - - - - - -
KODCOHLO_02295 1.11e-23 - - - - - - - -
KODCOHLO_02296 1.23e-69 tnrA - - K - - - transcriptional
KODCOHLO_02297 2.89e-308 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
KODCOHLO_02299 3.63e-309 ydhD - - M - - - Glycosyl hydrolase
KODCOHLO_02300 2.31e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KODCOHLO_02301 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_02302 2.66e-170 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KODCOHLO_02303 2.12e-188 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KODCOHLO_02304 7.39e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KODCOHLO_02305 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KODCOHLO_02306 7.29e-158 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KODCOHLO_02307 1.89e-275 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KODCOHLO_02308 8.91e-170 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
KODCOHLO_02309 2.38e-273 - - - M - - - Glycosyl transferase family 2
KODCOHLO_02311 5e-72 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KODCOHLO_02312 1.92e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
KODCOHLO_02313 6.08e-95 ohrR - - K - - - COG1846 Transcriptional regulators
KODCOHLO_02314 4.65e-91 ohrA - - O - - - Organic hydroperoxide resistance protein
KODCOHLO_02315 8.5e-285 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KODCOHLO_02316 1.02e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KODCOHLO_02317 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KODCOHLO_02318 1.22e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
KODCOHLO_02319 3.36e-68 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
KODCOHLO_02320 1.23e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KODCOHLO_02321 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
KODCOHLO_02322 8.11e-202 ykgA - - E - - - Amidinotransferase
KODCOHLO_02323 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
KODCOHLO_02324 6.62e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_02325 2.55e-216 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KODCOHLO_02326 1.68e-252 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KODCOHLO_02327 3.97e-226 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
KODCOHLO_02328 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KODCOHLO_02329 9.2e-243 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_02330 1.89e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KODCOHLO_02331 1.33e-202 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KODCOHLO_02332 3.58e-199 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
KODCOHLO_02333 0.0 yubD - - P - - - Major Facilitator Superfamily
KODCOHLO_02334 3.73e-276 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KODCOHLO_02336 5.21e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KODCOHLO_02337 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KODCOHLO_02338 2.9e-226 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KODCOHLO_02339 9.38e-312 steT - - E ko:K03294 - ko00000 amino acid
KODCOHLO_02340 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
KODCOHLO_02341 7.07e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
KODCOHLO_02342 7.37e-170 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
KODCOHLO_02343 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
KODCOHLO_02344 3.49e-215 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
KODCOHLO_02345 4.7e-52 xhlB - - S - - - SPP1 phage holin
KODCOHLO_02346 3.87e-51 xhlA - - S - - - Haemolysin XhlA
KODCOHLO_02347 1.23e-175 xepA - - - - - - -
KODCOHLO_02348 1.55e-38 xkdX - - - - - - -
KODCOHLO_02350 7.89e-111 - - - - - - - -
KODCOHLO_02351 2.98e-36 - - - - - - - -
KODCOHLO_02352 2.03e-112 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
KODCOHLO_02353 1.16e-180 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KODCOHLO_02355 1.27e-101 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KODCOHLO_02356 4.79e-57 ywiB - - S - - - protein conserved in bacteria
KODCOHLO_02357 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KODCOHLO_02358 2.03e-271 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
KODCOHLO_02359 7.4e-165 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
KODCOHLO_02360 4.34e-178 ywiC - - S - - - YwiC-like protein
KODCOHLO_02361 1.68e-108 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
KODCOHLO_02362 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KODCOHLO_02363 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
KODCOHLO_02364 8.57e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
KODCOHLO_02365 3.83e-155 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
KODCOHLO_02366 2.89e-134 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KODCOHLO_02367 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KODCOHLO_02368 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
KODCOHLO_02369 1.13e-58 ywjC - - - - - - -
KODCOHLO_02370 4.49e-232 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KODCOHLO_02371 9.51e-283 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KODCOHLO_02372 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
KODCOHLO_02373 2.79e-74 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KODCOHLO_02374 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KODCOHLO_02375 1.91e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
KODCOHLO_02376 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
KODCOHLO_02377 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
KODCOHLO_02378 3.69e-143 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KODCOHLO_02379 3.21e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KODCOHLO_02380 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
KODCOHLO_02381 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KODCOHLO_02382 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
KODCOHLO_02383 4.76e-133 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KODCOHLO_02384 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
KODCOHLO_02385 1.93e-200 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
KODCOHLO_02386 4.94e-122 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KODCOHLO_02387 9.07e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KODCOHLO_02388 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KODCOHLO_02389 6.39e-199 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KODCOHLO_02391 2.08e-79 ywlA - - S - - - Uncharacterised protein family (UPF0715)
KODCOHLO_02392 1.88e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
KODCOHLO_02393 2.02e-97 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
KODCOHLO_02394 3.08e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KODCOHLO_02395 3.91e-118 mntP - - P - - - Probably functions as a manganese efflux pump
KODCOHLO_02396 1.2e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KODCOHLO_02397 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
KODCOHLO_02398 7.42e-125 ywlG - - S - - - Belongs to the UPF0340 family
KODCOHLO_02399 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KODCOHLO_02400 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KODCOHLO_02401 1.51e-78 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
KODCOHLO_02402 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KODCOHLO_02403 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KODCOHLO_02404 5.54e-81 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KODCOHLO_02405 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KODCOHLO_02406 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KODCOHLO_02407 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KODCOHLO_02408 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KODCOHLO_02409 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KODCOHLO_02410 6.9e-116 ywmA - - - - - - -
KODCOHLO_02411 1.3e-44 ywzB - - S - - - membrane
KODCOHLO_02412 3.4e-174 ywmB - - S - - - TATA-box binding
KODCOHLO_02413 4.75e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KODCOHLO_02414 6.71e-241 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
KODCOHLO_02415 1.36e-146 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KODCOHLO_02416 1.75e-157 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KODCOHLO_02418 4.3e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KODCOHLO_02419 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KODCOHLO_02420 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KODCOHLO_02421 5e-106 ywmF - - S - - - Peptidase M50
KODCOHLO_02422 7.2e-18 csbD - - K - - - CsbD-like
KODCOHLO_02423 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
KODCOHLO_02424 1.07e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
KODCOHLO_02425 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KODCOHLO_02426 3.09e-88 ywnA - - K - - - Transcriptional regulator
KODCOHLO_02427 1.52e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
KODCOHLO_02428 1.1e-76 ywnC - - S - - - Family of unknown function (DUF5362)
KODCOHLO_02429 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KODCOHLO_02430 2.55e-90 ywnF - - S - - - Family of unknown function (DUF5392)
KODCOHLO_02432 2.76e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
KODCOHLO_02433 1.53e-187 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KODCOHLO_02434 5.45e-94 ywnJ - - S - - - VanZ like family
KODCOHLO_02435 1.59e-129 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
KODCOHLO_02436 7.81e-263 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KODCOHLO_02437 1.29e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
KODCOHLO_02438 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
KODCOHLO_02439 1.13e-132 yjgF - - Q - - - Isochorismatase family
KODCOHLO_02440 1.09e-309 ywoD - - EGP - - - Major facilitator superfamily
KODCOHLO_02441 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
KODCOHLO_02442 3.36e-271 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KODCOHLO_02443 7.23e-93 ywoH - - K - - - transcriptional
KODCOHLO_02444 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
KODCOHLO_02445 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
KODCOHLO_02446 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KODCOHLO_02447 1.74e-183 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KODCOHLO_02448 3.02e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
KODCOHLO_02449 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KODCOHLO_02450 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KODCOHLO_02451 1.07e-89 ywpF - - S - - - YwpF-like protein
KODCOHLO_02452 4.49e-82 ywpG - - - - - - -
KODCOHLO_02453 1.47e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
KODCOHLO_02454 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
KODCOHLO_02455 7.2e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KODCOHLO_02456 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KODCOHLO_02457 0.0 ywqB - - S - - - SWIM zinc finger
KODCOHLO_02458 1.74e-21 - - - - - - - -
KODCOHLO_02459 1.95e-149 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
KODCOHLO_02460 2.58e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KODCOHLO_02461 4.82e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
KODCOHLO_02462 2.05e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KODCOHLO_02463 1.34e-188 ywqG - - S - - - Domain of unknown function (DUF1963)
KODCOHLO_02465 4.22e-50 ywqI - - S - - - Family of unknown function (DUF5344)
KODCOHLO_02466 0.0 ywqJ - - S - - - Pre-toxin TG
KODCOHLO_02468 1.39e-201 - - - K - - - Transcriptional regulator
KODCOHLO_02469 1.23e-119 ywqN - - S - - - NAD(P)H-dependent
KODCOHLO_02471 2.03e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
KODCOHLO_02472 9.5e-129 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
KODCOHLO_02473 1.01e-109 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KODCOHLO_02474 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KODCOHLO_02476 5.72e-144 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KODCOHLO_02477 3.39e-25 - - - - - - - -
KODCOHLO_02478 6.23e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
KODCOHLO_02479 6.63e-172 cotB - - - ko:K06325 - ko00000 -
KODCOHLO_02480 4.87e-163 ywrJ - - - - - - -
KODCOHLO_02481 4.73e-301 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KODCOHLO_02483 2.18e-214 alsR - - K - - - LysR substrate binding domain
KODCOHLO_02484 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KODCOHLO_02485 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KODCOHLO_02486 7.13e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
KODCOHLO_02487 1.18e-115 batE - - T - - - Sh3 type 3 domain protein
KODCOHLO_02488 1.15e-206 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
KODCOHLO_02489 5.37e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KODCOHLO_02490 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KODCOHLO_02491 3.24e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KODCOHLO_02492 1.34e-199 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KODCOHLO_02493 1.43e-226 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
KODCOHLO_02494 3.56e-260 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
KODCOHLO_02495 8.49e-245 - - - E - - - Spore germination protein
KODCOHLO_02496 2.45e-253 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
KODCOHLO_02497 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
KODCOHLO_02498 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
KODCOHLO_02499 6.62e-279 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KODCOHLO_02500 4.04e-29 ywtC - - - - - - -
KODCOHLO_02501 9.79e-298 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KODCOHLO_02502 2.96e-75 yttA - - S - - - Pfam Transposase IS66
KODCOHLO_02503 7.2e-200 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KODCOHLO_02504 2.3e-229 ywtF_2 - - K - - - Transcriptional regulator
KODCOHLO_02505 8.17e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KODCOHLO_02506 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
KODCOHLO_02507 1.12e-267 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
KODCOHLO_02508 4.98e-251 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
KODCOHLO_02509 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KODCOHLO_02510 8.41e-235 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KODCOHLO_02511 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KODCOHLO_02512 2.39e-275 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KODCOHLO_02513 8.69e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KODCOHLO_02514 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
KODCOHLO_02515 0.0 - - - M - - - Glycosyltransferase like family 2
KODCOHLO_02516 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KODCOHLO_02517 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
KODCOHLO_02518 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KODCOHLO_02519 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KODCOHLO_02520 4.74e-266 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KODCOHLO_02521 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KODCOHLO_02522 1.86e-64 - - - - - - - -
KODCOHLO_02523 0.0 lytB - - D - - - Stage II sporulation protein
KODCOHLO_02524 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KODCOHLO_02525 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KODCOHLO_02526 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KODCOHLO_02527 6.46e-285 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
KODCOHLO_02528 1.86e-316 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KODCOHLO_02529 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
KODCOHLO_02530 3.49e-148 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
KODCOHLO_02531 2.82e-185 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
KODCOHLO_02532 4.12e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
KODCOHLO_02533 0.0 - - - S - - - Capsid protein (F protein)
KODCOHLO_02534 9.49e-103 - - - S - - - Bacteriophage scaffolding protein D
KODCOHLO_02535 4.71e-56 - - - S - - - Phage protein C
KODCOHLO_02536 0.0 - - - S - - - Bacteriophage replication gene A protein (GPA)
KODCOHLO_02537 1.15e-190 - - - S - - - Microvirus H protein (pilot protein)
KODCOHLO_02538 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KODCOHLO_02539 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_02540 0.0 yycH - - S - - - protein conserved in bacteria
KODCOHLO_02541 1.98e-194 yycI - - S - - - protein conserved in bacteria
KODCOHLO_02542 1.98e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KODCOHLO_02543 5.44e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KODCOHLO_02544 1.34e-13 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KODCOHLO_02545 2.06e-314 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KODCOHLO_02546 3.82e-240 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
KODCOHLO_02547 0.0 - - - - - - - -
KODCOHLO_02548 1.85e-252 - - - S - - - Major Facilitator Superfamily
KODCOHLO_02549 0.0 - - - S - - - ABC transporter
KODCOHLO_02550 7.53e-188 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
KODCOHLO_02551 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KODCOHLO_02552 6.09e-296 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
KODCOHLO_02553 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KODCOHLO_02554 2.64e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KODCOHLO_02555 1.51e-258 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
KODCOHLO_02557 8.36e-113 yycN - - K - - - Acetyltransferase
KODCOHLO_02558 6.14e-233 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
KODCOHLO_02559 1.13e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KODCOHLO_02560 5.83e-273 yycP - - - - - - -
KODCOHLO_02563 3.38e-104 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KODCOHLO_02564 2.01e-245 - - - L - - - Protein of unknown function (DUF1524)
KODCOHLO_02566 1.31e-26 - - - - - - - -
KODCOHLO_02567 1.06e-232 - - - S - - - Fusaric acid resistance protein-like
KODCOHLO_02568 1.5e-232 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KODCOHLO_02569 1.15e-113 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
KODCOHLO_02570 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KODCOHLO_02571 5.24e-195 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KODCOHLO_02572 4.73e-108 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KODCOHLO_02573 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
KODCOHLO_02574 1.02e-311 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KODCOHLO_02575 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
KODCOHLO_02576 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
KODCOHLO_02577 9.04e-161 - - - E - - - Ring-cleavage extradiol dioxygenase
KODCOHLO_02578 6.42e-96 yxaI - - S - - - membrane protein domain
KODCOHLO_02579 1.8e-254 - - - EGP - - - Major Facilitator Superfamily
KODCOHLO_02580 5.77e-66 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KODCOHLO_02581 1.02e-84 - - - S - - - Family of unknown function (DUF5391)
KODCOHLO_02582 1.45e-190 yxaL - - S - - - PQQ-like domain
KODCOHLO_02583 9.34e-317 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KODCOHLO_02584 4.26e-272 yxbF - - K - - - Bacterial regulatory proteins, tetR family
KODCOHLO_02585 1.38e-252 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
KODCOHLO_02586 4.8e-254 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_02587 1.07e-131 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KODCOHLO_02588 3.41e-192 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KODCOHLO_02590 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
KODCOHLO_02591 6.38e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KODCOHLO_02592 6.81e-222 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
KODCOHLO_02593 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KODCOHLO_02594 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KODCOHLO_02595 6.68e-198 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KODCOHLO_02596 3.82e-229 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KODCOHLO_02597 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KODCOHLO_02598 4.44e-221 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KODCOHLO_02599 5.22e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
KODCOHLO_02600 4.97e-248 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KODCOHLO_02601 6.24e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
KODCOHLO_02602 1.47e-14 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KODCOHLO_02603 5.36e-172 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KODCOHLO_02604 1.76e-198 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KODCOHLO_02605 9.37e-159 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KODCOHLO_02606 6.53e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_02607 1.89e-181 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_02608 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KODCOHLO_02609 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
KODCOHLO_02610 1.75e-229 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KODCOHLO_02611 4.62e-45 - - - - - - - -
KODCOHLO_02612 5.09e-35 yxeD - - - - - - -
KODCOHLO_02614 3.81e-33 yxeE - - - - - - -
KODCOHLO_02617 1.91e-192 yxeH - - S - - - hydrolases of the HAD superfamily
KODCOHLO_02618 2.36e-219 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KODCOHLO_02619 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KODCOHLO_02620 2.33e-264 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KODCOHLO_02621 1.1e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
KODCOHLO_02622 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KODCOHLO_02623 6.55e-223 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KODCOHLO_02624 5.88e-295 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
KODCOHLO_02625 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KODCOHLO_02626 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
KODCOHLO_02627 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KODCOHLO_02628 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
KODCOHLO_02630 2.13e-177 - - - L - - - Protein of unknown function (DUF2726)
KODCOHLO_02631 6.86e-85 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KODCOHLO_02632 0.0 - - - L - - - HKD family nuclease
KODCOHLO_02633 4.21e-95 yxiE - - T - - - Belongs to the universal stress protein A family
KODCOHLO_02634 1.99e-206 yxxF - - EG - - - EamA-like transporter family
KODCOHLO_02635 6.09e-254 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
KODCOHLO_02636 0.0 wapA - - M - - - COG3209 Rhs family protein
KODCOHLO_02639 8.15e-101 - - - - - - - -
KODCOHLO_02640 8.89e-138 - - - - - - - -
KODCOHLO_02642 1.6e-25 - - - - - - - -
KODCOHLO_02643 1.63e-62 yxiI - - S - - - Protein of unknown function (DUF2716)
KODCOHLO_02644 4.09e-80 - - - S - - - SMI1-KNR4 cell-wall
KODCOHLO_02647 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KODCOHLO_02648 5.8e-279 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
KODCOHLO_02649 1e-134 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KODCOHLO_02651 9.11e-182 bglS - - M - - - licheninase activity
KODCOHLO_02652 2.23e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KODCOHLO_02653 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KODCOHLO_02654 1.96e-64 yxiS - - - - - - -
KODCOHLO_02655 1.47e-116 - - - T - - - Domain of unknown function (DUF4163)
KODCOHLO_02656 5.75e-267 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KODCOHLO_02657 9.47e-188 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KODCOHLO_02658 2.21e-229 yvhJ - - K - - - Transcriptional regulator
KODCOHLO_02659 3.43e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
KODCOHLO_02660 1.4e-246 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KODCOHLO_02661 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KODCOHLO_02662 5.95e-202 degV - - S - - - protein conserved in bacteria
KODCOHLO_02663 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KODCOHLO_02664 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
KODCOHLO_02665 6.79e-98 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
KODCOHLO_02666 2.23e-97 yvyF - - S - - - flagellar protein
KODCOHLO_02667 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
KODCOHLO_02668 2.2e-105 yvyG - - NOU - - - FlgN protein
KODCOHLO_02669 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
KODCOHLO_02670 2.82e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
KODCOHLO_02671 2.8e-108 yviE - - - - - - -
KODCOHLO_02672 2.48e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KODCOHLO_02673 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KODCOHLO_02674 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KODCOHLO_02675 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KODCOHLO_02676 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
KODCOHLO_02677 3.08e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
KODCOHLO_02678 1.35e-89 - - - - - - - -
KODCOHLO_02679 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KODCOHLO_02680 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KODCOHLO_02681 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KODCOHLO_02682 2.29e-190 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KODCOHLO_02683 3.08e-60 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KODCOHLO_02684 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
KODCOHLO_02685 5e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KODCOHLO_02686 9.93e-304 ywoF - - P - - - Right handed beta helix region
KODCOHLO_02687 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KODCOHLO_02688 2.47e-73 swrA - - S - - - Swarming motility protein
KODCOHLO_02689 7.21e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KODCOHLO_02691 8.04e-296 yvkA - - P - - - -transporter
KODCOHLO_02692 1.91e-143 yvkB - - K - - - Transcriptional regulator
KODCOHLO_02693 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
KODCOHLO_02694 2.59e-45 csbA - - S - - - protein conserved in bacteria
KODCOHLO_02695 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KODCOHLO_02696 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KODCOHLO_02697 8.07e-44 yvkN - - - - - - -
KODCOHLO_02698 4.87e-66 yvlA - - - - - - -
KODCOHLO_02699 9.16e-218 yvlB - - S - - - Putative adhesin
KODCOHLO_02700 2.33e-35 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
KODCOHLO_02701 3.12e-65 yvlD - - S ko:K08972 - ko00000 Membrane
KODCOHLO_02702 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
KODCOHLO_02703 1.73e-133 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KODCOHLO_02704 4.29e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
KODCOHLO_02705 2.22e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KODCOHLO_02706 7.52e-283 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KODCOHLO_02707 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KODCOHLO_02708 7.18e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KODCOHLO_02709 1.06e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KODCOHLO_02710 1.98e-109 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KODCOHLO_02711 8.4e-177 yvpB - - NU - - - protein conserved in bacteria
KODCOHLO_02712 3.34e-267 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KODCOHLO_02713 7.47e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KODCOHLO_02714 6.13e-296 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KODCOHLO_02715 3.35e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
KODCOHLO_02716 5.69e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KODCOHLO_02717 4.42e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KODCOHLO_02718 4.44e-173 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KODCOHLO_02719 4.7e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
KODCOHLO_02724 2.09e-99 - - - L - - - dnaD_dom DnaD domain protein
KODCOHLO_02726 6.41e-50 - - - S - - - Domain of unknown function (DUF771)
KODCOHLO_02727 7.47e-07 - - - K - - - Helix-turn-helix XRE-family like proteins
KODCOHLO_02728 1.7e-32 - - - K - - - Transcriptional
KODCOHLO_02731 4.73e-93 - - - - - - - -
KODCOHLO_02732 1.07e-169 - - - L - - - Phage integrase family
KODCOHLO_02733 1.24e-37 - - - - - - - -
KODCOHLO_02734 1.87e-69 - - - - - - - -
KODCOHLO_02735 1.61e-99 - - - - - - - -
KODCOHLO_02736 1.73e-132 - - - NU ko:K02283 - ko00000,ko02035,ko02044 Secretion system protein
KODCOHLO_02740 7.55e-264 - - - M - - - domain protein
KODCOHLO_02742 4.98e-36 - - - S - - - Domain of unknown function (DUF5052)
KODCOHLO_02745 1.91e-07 - - - K ko:K22299 - ko00000,ko03000 Helix-turn-helix domain
KODCOHLO_02748 6.57e-21 - - - - - - - -
KODCOHLO_02750 8.15e-233 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
KODCOHLO_02752 4.51e-78 - - - - - - - -
KODCOHLO_02753 8.58e-40 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KODCOHLO_02754 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KODCOHLO_02755 3.28e-68 - - - - - - - -
KODCOHLO_02756 1.33e-156 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KODCOHLO_02757 1.85e-243 sasA - - T - - - Histidine kinase
KODCOHLO_02758 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
KODCOHLO_02759 3.05e-203 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
KODCOHLO_02760 8.99e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KODCOHLO_02761 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KODCOHLO_02762 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KODCOHLO_02763 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KODCOHLO_02764 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KODCOHLO_02765 3.23e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
KODCOHLO_02766 8.09e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
KODCOHLO_02767 8.99e-104 - - - M - - - Ribonuclease
KODCOHLO_02768 2.81e-231 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KODCOHLO_02769 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KODCOHLO_02770 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
KODCOHLO_02771 7.55e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
KODCOHLO_02772 3.78e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KODCOHLO_02773 0.0 - - - EGP - - - Sugar (and other) transporter
KODCOHLO_02774 2.75e-268 yraM - - S - - - PrpF protein
KODCOHLO_02777 5.24e-22 - - - V - - - HNH endonuclease
KODCOHLO_02778 2.13e-58 - - - - - - - -
KODCOHLO_02779 0.0 - - - L - - - Phage Terminase
KODCOHLO_02780 4.91e-227 - - - S - - - Phage portal protein
KODCOHLO_02781 1.37e-109 - - - OU - - - Clp protease
KODCOHLO_02782 9.11e-188 - - - S - - - Phage capsid family
KODCOHLO_02783 1.81e-05 - - - - - - - -
KODCOHLO_02784 2.88e-29 - - - - - - - -
KODCOHLO_02785 3.54e-30 - - - S - - - head-tail adaptor
KODCOHLO_02787 3.28e-13 - - - S - - - TIGRFAM phage protein, HK97 gp10 family
KODCOHLO_02788 8.37e-21 - - - N - - - Maj_tail_phi13 phage major tail , phi13 family protein
KODCOHLO_02789 0.000258 - - - - - - - -
KODCOHLO_02791 2.61e-167 - - - D - - - phage tail tape measure protein
KODCOHLO_02793 3.46e-124 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
KODCOHLO_02794 0.0 - - - M - - - Pectate lyase superfamily protein
KODCOHLO_02795 7.25e-219 - - - S - - - Domain of unknown function (DUF2479)
KODCOHLO_02797 9.5e-08 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
KODCOHLO_02798 7.53e-75 - - - S - - - Pfam:Phage_holin_4_1
KODCOHLO_02799 9.49e-10 - - - S - - - amine dehydrogenase activity
KODCOHLO_02803 2.68e-39 - - - S - - - Acetyltransferase (GNAT) domain
KODCOHLO_02804 3.29e-115 yokK - - S - - - SMI1 / KNR4 family
KODCOHLO_02805 3.88e-68 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
KODCOHLO_02806 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KODCOHLO_02807 1.02e-101 yokH - - G - - - SMI1 / KNR4 family
KODCOHLO_02809 0.0 yokA - - L - - - Recombinase
KODCOHLO_02810 1.45e-135 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KODCOHLO_02811 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KODCOHLO_02812 1.7e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KODCOHLO_02813 3.35e-89 ypoP - - K - - - transcriptional
KODCOHLO_02814 1.6e-125 ypmS - - S - - - protein conserved in bacteria
KODCOHLO_02815 1.43e-173 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
KODCOHLO_02816 7.51e-145 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KODCOHLO_02817 6.87e-50 ypmP - - S - - - Protein of unknown function (DUF2535)
KODCOHLO_02818 1.73e-308 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KODCOHLO_02819 1.59e-221 yplP - - K - - - Transcriptional regulator
KODCOHLO_02820 5.24e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
KODCOHLO_02821 4.71e-148 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KODCOHLO_02822 5.2e-118 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KODCOHLO_02823 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KODCOHLO_02824 2.17e-146 ypjP - - S - - - YpjP-like protein
KODCOHLO_02825 2.02e-171 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
KODCOHLO_02826 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
KODCOHLO_02827 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
KODCOHLO_02828 3.51e-200 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
KODCOHLO_02829 3.97e-129 yagB - - S ko:K06950 - ko00000 phosphohydrolase
KODCOHLO_02830 6.26e-110 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
KODCOHLO_02831 1.33e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KODCOHLO_02832 9e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KODCOHLO_02833 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
KODCOHLO_02834 5.19e-17 degR - - - - - - -
KODCOHLO_02835 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
KODCOHLO_02836 6.59e-40 ypeQ - - S - - - Zinc-finger
KODCOHLO_02837 8.39e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
KODCOHLO_02838 9.33e-153 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KODCOHLO_02839 2.47e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
KODCOHLO_02841 1.34e-149 ypcP - - L - - - 5'3' exonuclease
KODCOHLO_02842 1.97e-73 - - - Q - - - Thioesterase domain
KODCOHLO_02843 1.62e-19 - - - - - - - -
KODCOHLO_02844 4.49e-155 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KODCOHLO_02845 2.48e-183 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KODCOHLO_02846 9.14e-172 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_02847 8.72e-105 - - - KT - - - helix_turn_helix, Lux Regulon
KODCOHLO_02848 1.76e-132 - - - T - - - Histidine kinase
KODCOHLO_02849 6.4e-117 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KODCOHLO_02850 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KODCOHLO_02851 5.62e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KODCOHLO_02852 9.9e-68 - - - S ko:K06518 - ko00000,ko02000 LrgA family
KODCOHLO_02853 6.05e-135 yxaC - - M - - - effector of murein hydrolase
KODCOHLO_02854 2.43e-205 dkgB - - S - - - Aldo/keto reductase family
KODCOHLO_02855 2.51e-118 - - - H - - - Tellurite resistance protein TehB
KODCOHLO_02857 0.0 - - - KLT - - - Protein kinase domain
KODCOHLO_02858 8.23e-138 - - - S - - - ABC-2 family transporter protein
KODCOHLO_02859 6.85e-196 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KODCOHLO_02860 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KODCOHLO_02861 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KODCOHLO_02862 1.05e-299 ybbR - - S - - - protein conserved in bacteria
KODCOHLO_02863 1.82e-187 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KODCOHLO_02864 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KODCOHLO_02865 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KODCOHLO_02870 9.77e-150 - - - S - - - ATPase (AAA superfamily
KODCOHLO_02871 7.68e-56 - - - - - - - -
KODCOHLO_02872 4.74e-170 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KODCOHLO_02873 1.27e-190 - - - S - - - Serine aminopeptidase, S33
KODCOHLO_02874 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
KODCOHLO_02875 1.83e-174 - - - I ko:K01066 - ko00000,ko01000 esterase
KODCOHLO_02876 3.38e-60 ohrB - - O - - - OsmC-like protein
KODCOHLO_02877 3.16e-64 ohrR - - K - - - Transcriptional regulator
KODCOHLO_02878 2.15e-92 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
KODCOHLO_02879 8.69e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
KODCOHLO_02880 1.41e-83 - - - S - - - YjbR
KODCOHLO_02881 3.75e-93 ywnA - - K - - - Transcriptional regulator
KODCOHLO_02882 7.44e-143 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
KODCOHLO_02883 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
KODCOHLO_02884 2.63e-53 yrkD - - S - - - protein conserved in bacteria
KODCOHLO_02885 1.38e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
KODCOHLO_02886 9.11e-24 - - - P - - - Rhodanese Homology Domain
KODCOHLO_02887 1.8e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
KODCOHLO_02888 1.23e-255 yrkH - - P - - - Rhodanese Homology Domain
KODCOHLO_02889 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
KODCOHLO_02890 2.42e-164 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
KODCOHLO_02891 2.11e-149 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KODCOHLO_02892 3e-133 - - - S - - - Protein of unknown function (DUF2812)
KODCOHLO_02893 7.89e-66 - - - K - - - Transcriptional regulator PadR-like family
KODCOHLO_02894 6.15e-233 - - - S - - - Patatin-like phospholipase
KODCOHLO_02895 1.18e-108 - - - S - - - DinB superfamily
KODCOHLO_02896 4.5e-144 dpaL 4.3.1.15 - E ko:K01751 - ko00000,ko01000 Pyridoxal-phosphate dependent enzyme
KODCOHLO_02897 6.58e-86 - - - K - - - COG1802 Transcriptional regulators
KODCOHLO_02898 4.46e-52 - - - J - - - Endoribonuclease L-PSP
KODCOHLO_02899 8.01e-177 - - - E ko:K03837 - ko00000,ko02000 Serine transporter
KODCOHLO_02900 3.52e-205 - - - E - - - Peptidase dimerisation domain
KODCOHLO_02901 5.7e-161 - - - K - - - helix_turn_helix, arabinose operon control protein
KODCOHLO_02902 3.83e-219 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KODCOHLO_02903 1.01e-295 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KODCOHLO_02904 3.08e-242 ydeG - - EGP - - - Major facilitator superfamily
KODCOHLO_02905 1.85e-37 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KODCOHLO_02908 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
KODCOHLO_02909 5.55e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
KODCOHLO_02910 3.78e-248 trkA - - P ko:K07222 - ko00000 Oxidoreductase
KODCOHLO_02911 5.47e-130 yrkC - - G - - - Cupin domain
KODCOHLO_02912 6.88e-68 ydeH - - - - - - -
KODCOHLO_02917 2.23e-51 - - - S - - - YjcQ protein
KODCOHLO_02918 2.24e-208 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
KODCOHLO_02919 1.81e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
KODCOHLO_02920 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
KODCOHLO_02921 4.3e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KODCOHLO_02922 5.44e-281 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
KODCOHLO_02923 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KODCOHLO_02924 7.49e-236 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KODCOHLO_02925 2.37e-271 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KODCOHLO_02926 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KODCOHLO_02927 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KODCOHLO_02928 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KODCOHLO_02929 1.19e-178 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KODCOHLO_02930 9.38e-158 - - - S - - - Haloacid dehalogenase-like hydrolase
KODCOHLO_02932 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
KODCOHLO_02934 1.91e-31 yjfB - - S - - - Putative motility protein
KODCOHLO_02935 2.76e-86 yjgA - - T - - - Protein of unknown function (DUF2809)
KODCOHLO_02936 1.94e-129 yjgB - - S - - - Domain of unknown function (DUF4309)
KODCOHLO_02937 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
KODCOHLO_02938 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
KODCOHLO_02939 1.48e-287 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KODCOHLO_02940 3.04e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KODCOHLO_02941 1.73e-40 - - - - - - - -
KODCOHLO_02942 2.67e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KODCOHLO_02943 1.45e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
KODCOHLO_02944 2.96e-164 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
KODCOHLO_02945 2.66e-223 yjlA - - EG - - - Putative multidrug resistance efflux transporter
KODCOHLO_02946 1.22e-118 yjlB - - S - - - Cupin domain
KODCOHLO_02947 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
KODCOHLO_02948 3.56e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KODCOHLO_02949 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
KODCOHLO_02950 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
KODCOHLO_02951 9.79e-233 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
KODCOHLO_02952 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
KODCOHLO_02953 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
KODCOHLO_02954 7.56e-166 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
KODCOHLO_02955 1.19e-102 yjoA - - S - - - DinB family
KODCOHLO_02956 1.55e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KODCOHLO_02958 1.84e-213 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KODCOHLO_02959 2.73e-80 yjqA - - S - - - Bacterial PH domain
KODCOHLO_02960 7.55e-142 yjqB - - S - - - phage-related replication protein
KODCOHLO_02962 7.61e-144 xkdA - - E - - - IrrE N-terminal-like domain
KODCOHLO_02963 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
KODCOHLO_02965 2.32e-191 xkdC - - L - - - Bacterial dnaA protein
KODCOHLO_02969 6.16e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KODCOHLO_02970 2.38e-140 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
KODCOHLO_02971 7.07e-265 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
KODCOHLO_02972 2.55e-303 xkdE3 - - S - - - portal protein
KODCOHLO_02973 2.52e-118 xkdF3 - - L - - - Putative phage serine protease XkdF
KODCOHLO_02974 2.9e-203 xkdG - - S - - - Phage capsid family
KODCOHLO_02975 2.17e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
KODCOHLO_02976 2.02e-56 - - - S - - - Domain of unknown function (DUF3599)
KODCOHLO_02977 1.39e-76 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
KODCOHLO_02978 4.99e-73 xkdJ - - - - - - -
KODCOHLO_02979 3.86e-21 - - - - - - - -
KODCOHLO_02980 1.63e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
KODCOHLO_02981 8.21e-97 xkdM - - S - - - Phage tail tube protein
KODCOHLO_02982 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
KODCOHLO_02983 4.33e-27 - - - - - - - -
KODCOHLO_02985 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_02986 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_02987 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_02990 5.06e-74 - - - - - - - -
KODCOHLO_02991 2.19e-80 xkdS - - S - - - Protein of unknown function (DUF2634)
KODCOHLO_02992 8.16e-42 xkdR - - S - - - Protein of unknown function (DUF2577)
KODCOHLO_02993 2.12e-208 xkdQ - - G - - - NLP P60 protein
KODCOHLO_02994 6.56e-145 xkdP - - S - - - Lysin motif
KODCOHLO_02995 0.0 xkdO - - L - - - Transglycosylase SLT domain
KODCOHLO_02996 8.03e-19 - - - - - - - -
KODCOHLO_02997 2.25e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
KODCOHLO_02998 2.02e-97 xkdM - - S - - - Phage tail tube protein
KODCOHLO_02999 8.65e-297 xkdK - - S - - - Phage tail sheath C-terminal domain
KODCOHLO_03000 4.78e-30 - - - - - - - -
KODCOHLO_03001 4.55e-84 yqbJ - - - - - - -
KODCOHLO_03002 1.84e-105 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KODCOHLO_03003 6.05e-68 yqbH - - S - - - Domain of unknown function (DUF3599)
KODCOHLO_03004 4.68e-64 - - - S - - - Protein of unknown function (DUF3199)
KODCOHLO_03005 9.52e-34 - - - S - - - YqbF, hypothetical protein domain
KODCOHLO_03006 1.2e-195 xkdG - - S - - - Phage capsid family
KODCOHLO_03007 2.85e-130 yqbD - - L - - - Putative phage serine protease XkdF
KODCOHLO_03009 4.62e-174 - - - S - - - Phage Mu protein F like protein
KODCOHLO_03010 0.0 yqbA - - S - - - portal protein
KODCOHLO_03011 3.67e-287 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
KODCOHLO_03012 3.2e-86 - - - - - - - -
KODCOHLO_03014 1.99e-35 - - - - - - - -
KODCOHLO_03016 3.57e-160 - - - J - - - protein-(glutamine-N5) methyltransferase activity
KODCOHLO_03017 3.35e-94 yvgO - - - - - - -
KODCOHLO_03018 0.000106 - - - - - - - -
KODCOHLO_03019 4.34e-58 - - - - - - - -
KODCOHLO_03022 3.31e-48 - - - - - - - -
KODCOHLO_03023 7.68e-62 - - - - - - - -
KODCOHLO_03029 8.83e-21 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
KODCOHLO_03031 6.97e-90 - - - - - - - -
KODCOHLO_03032 4.46e-80 rusA - - L - - - Endodeoxyribonuclease RusA
KODCOHLO_03035 6.8e-223 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KODCOHLO_03037 4.03e-48 - - - L - - - primosome component and related proteins
KODCOHLO_03039 4e-130 - - - S - - - Metallo-beta-lactamase superfamily
KODCOHLO_03040 3.84e-123 - - - L ko:K07455 - ko00000,ko03400 RecT protein
KODCOHLO_03042 9.02e-223 - - - D - - - nuclear chromosome segregation
KODCOHLO_03047 6.93e-37 prtR - - K - - - Helix-turn-helix XRE-family like proteins
KODCOHLO_03048 1.62e-19 - - - S - - - Helix-turn-helix domain
KODCOHLO_03050 8.05e-21 - - - K - - - Helix-turn-helix domain
KODCOHLO_03052 2.97e-30 xkdA - - E - - - IrrE N-terminal-like domain
KODCOHLO_03053 1.22e-98 - - - L - - - Phage integrase, N-terminal SAM-like domain
KODCOHLO_03056 1e-134 - - - S - - - Sodium Bile acid symporter family
KODCOHLO_03057 1.06e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
KODCOHLO_03058 2.09e-86 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
KODCOHLO_03059 4.37e-285 nhaC_1 - - C - - - antiporter
KODCOHLO_03060 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
KODCOHLO_03061 8.46e-146 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_03063 5.9e-248 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
KODCOHLO_03064 4.7e-130 ydeS - - K - - - Transcriptional regulator
KODCOHLO_03066 3.45e-64 yraD - - M ko:K06439 - ko00000 Spore coat protein
KODCOHLO_03067 2.4e-33 yraE - - - ko:K06440 - ko00000 -
KODCOHLO_03068 3.98e-278 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KODCOHLO_03069 4.76e-84 yraF - - M - - - Spore coat protein
KODCOHLO_03070 9.9e-49 yraG - - - ko:K06440 - ko00000 -
KODCOHLO_03071 2e-274 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_03072 1.39e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KODCOHLO_03073 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
KODCOHLO_03074 3.98e-170 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
KODCOHLO_03075 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
KODCOHLO_03076 3.57e-125 ynaD - - J - - - Acetyltransferase (GNAT) domain
KODCOHLO_03077 6.07e-192 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KODCOHLO_03078 1.08e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
KODCOHLO_03079 2.75e-268 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
KODCOHLO_03080 1.31e-286 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KODCOHLO_03081 1.84e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
KODCOHLO_03082 1.43e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
KODCOHLO_03083 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
KODCOHLO_03084 1.19e-192 bltR - - K - - - helix_turn_helix, mercury resistance
KODCOHLO_03085 1.04e-190 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KODCOHLO_03086 3.19e-145 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KODCOHLO_03087 1.83e-185 - - - Q - - - ubiE/COQ5 methyltransferase family
KODCOHLO_03088 4.35e-212 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Isocitrate/isopropylmalate dehydrogenase
KODCOHLO_03089 7.66e-153 ydhC - - K - - - FCD
KODCOHLO_03090 2.65e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KODCOHLO_03093 0.0 pbpE - - V - - - Beta-lactamase
KODCOHLO_03095 4.3e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
KODCOHLO_03096 2.24e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
KODCOHLO_03097 2.4e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
KODCOHLO_03098 1.09e-152 - - - K ko:K05799 - ko00000,ko03000 FCD
KODCOHLO_03099 1.18e-274 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
KODCOHLO_03100 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
KODCOHLO_03101 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KODCOHLO_03102 4.07e-133 yvdT_1 - - K - - - Transcriptional regulator
KODCOHLO_03103 0.0 ybeC - - E - - - amino acid
KODCOHLO_03104 4.06e-210 ydhU - - P ko:K07217 - ko00000 Catalase
KODCOHLO_03105 2.7e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
KODCOHLO_03106 5.24e-233 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
KODCOHLO_03107 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KODCOHLO_03110 1.52e-170 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KODCOHLO_03111 1.82e-189 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KODCOHLO_03112 1.99e-202 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KODCOHLO_03113 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KODCOHLO_03114 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KODCOHLO_03115 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
KODCOHLO_03116 6.52e-103 ypmB - - S - - - protein conserved in bacteria
KODCOHLO_03117 1.7e-282 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KODCOHLO_03118 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
KODCOHLO_03119 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
KODCOHLO_03120 4e-155 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KODCOHLO_03121 1.8e-119 ypoC - - - - - - -
KODCOHLO_03122 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KODCOHLO_03123 7.27e-145 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KODCOHLO_03124 2e-239 yppC - - S - - - Protein of unknown function (DUF2515)
KODCOHLO_03125 0.000542 - - - - ko:K06430 - ko00000 -
KODCOHLO_03129 9.54e-81 yppG - - S - - - YppG-like protein
KODCOHLO_03130 7.23e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KODCOHLO_03131 9.93e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
KODCOHLO_03132 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KODCOHLO_03133 6.13e-297 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
KODCOHLO_03135 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
KODCOHLO_03136 4.46e-127 ypsA - - S - - - Belongs to the UPF0398 family
KODCOHLO_03137 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KODCOHLO_03138 3.16e-274 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KODCOHLO_03139 6.91e-31 - - - S - - - YpzG-like protein
KODCOHLO_03141 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
KODCOHLO_03142 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KODCOHLO_03143 5.51e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KODCOHLO_03144 3.57e-298 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
KODCOHLO_03145 1.32e-06 - - - - - - - -
KODCOHLO_03146 4.25e-128 yrdC - - Q - - - Isochorismatase family
KODCOHLO_03147 5.01e-75 ydfR - - S - - - Protein of unknown function (DUF421)
KODCOHLO_03148 9.22e-27 ydfR - - S - - - Protein of unknown function (DUF421)
KODCOHLO_03149 8.58e-09 - - - S - - - Bacillus cereus group antimicrobial protein
KODCOHLO_03150 1.17e-65 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
KODCOHLO_03151 1.77e-136 - - - J - - - Acetyltransferase (GNAT) domain
KODCOHLO_03152 9.52e-264 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
KODCOHLO_03153 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
KODCOHLO_03154 0.0 ypbR - - S - - - Dynamin family
KODCOHLO_03155 1.17e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
KODCOHLO_03156 2.44e-10 - - - - - - - -
KODCOHLO_03157 2.07e-37 xhlB - - S - - - SPP1 phage holin
KODCOHLO_03158 1.19e-40 xhlA - - S - - - Haemolysin XhlA
KODCOHLO_03159 1.64e-24 xkdX - - - - - - -
KODCOHLO_03161 4.93e-71 - - - - - - - -
KODCOHLO_03162 5.24e-80 - - - - - - - -
KODCOHLO_03163 1.12e-126 - - - S - - - homolog of phage Mu protein gp47
KODCOHLO_03164 2.39e-32 - - - S - - - Protein of unknown function (DUF2634)
KODCOHLO_03165 3.21e-35 - - - - - - - -
KODCOHLO_03166 5.05e-109 - - - - - - - -
KODCOHLO_03167 5.45e-31 - - - - - - - -
KODCOHLO_03168 6.66e-55 - - - M - - - LysM domain
KODCOHLO_03169 9.58e-183 - - - N - - - phage tail tape measure protein
KODCOHLO_03170 1.65e-19 - - - - - - - -
KODCOHLO_03171 2.25e-46 - - - - - - - -
KODCOHLO_03172 3.57e-130 - - - S - - - Protein of unknown function (DUF3383)
KODCOHLO_03173 2.96e-41 - - - - - - - -
KODCOHLO_03175 8.55e-62 - - - - - - - -
KODCOHLO_03177 2.45e-40 - - - S - - - Phage Mu protein F like protein
KODCOHLO_03179 1.88e-155 - - - S - - - P22 coat protein - gene protein 5
KODCOHLO_03180 1.72e-66 - - - S - - - Domain of unknown function (DUF4355)
KODCOHLO_03181 1.96e-50 - - - S - - - Protein of unknown function (DUF2829)
KODCOHLO_03183 9.48e-194 - - - S - - - Phage portal protein, SPP1 Gp6-like
KODCOHLO_03184 4.95e-233 - - - S - - - Terminase-like family
KODCOHLO_03185 5.01e-112 yqaS - - L - - - DNA packaging
KODCOHLO_03187 9.97e-62 - - - L - - - Transposase
KODCOHLO_03190 8.33e-238 yueF - - S - - - transporter activity
KODCOHLO_03192 4.21e-72 - - - S - - - YolD-like protein
KODCOHLO_03193 5.45e-298 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KODCOHLO_03194 1.1e-112 yqjY - - K ko:K06977 - ko00000 acetyltransferase
KODCOHLO_03195 9.91e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
KODCOHLO_03196 2.79e-221 yqkA - - K - - - GrpB protein
KODCOHLO_03197 2.2e-79 yqkB - - S - - - Belongs to the HesB IscA family
KODCOHLO_03198 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
KODCOHLO_03199 9.62e-225 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KODCOHLO_03200 2.97e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
KODCOHLO_03201 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
KODCOHLO_03202 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
KODCOHLO_03203 5.91e-280 yqxK - - L - - - DNA helicase
KODCOHLO_03204 4e-76 ansR - - K - - - Transcriptional regulator
KODCOHLO_03205 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
KODCOHLO_03206 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
KODCOHLO_03207 1.19e-311 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
KODCOHLO_03208 2.38e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
KODCOHLO_03209 1.96e-30 - - - - - - - -
KODCOHLO_03210 8.54e-45 yqkK - - - - - - -
KODCOHLO_03212 5.01e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KODCOHLO_03213 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KODCOHLO_03214 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
KODCOHLO_03215 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
KODCOHLO_03216 2.88e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KODCOHLO_03217 2.13e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KODCOHLO_03218 2.03e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KODCOHLO_03219 4e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
KODCOHLO_03220 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KODCOHLO_03221 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KODCOHLO_03222 6.68e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
KODCOHLO_03223 2.03e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
KODCOHLO_03224 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
KODCOHLO_03225 5.53e-242 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
KODCOHLO_03226 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
KODCOHLO_03227 3.08e-141 - - - S ko:K06407 - ko00000 stage V sporulation protein
KODCOHLO_03228 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
KODCOHLO_03229 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KODCOHLO_03230 3.65e-198 ypuA - - S - - - Secreted protein
KODCOHLO_03231 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KODCOHLO_03232 5.56e-105 ccdC1 - - O - - - Protein of unknown function (DUF1453)
KODCOHLO_03233 6.56e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KODCOHLO_03234 2.85e-70 ypuD - - - - - - -
KODCOHLO_03235 3.09e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KODCOHLO_03236 8.02e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
KODCOHLO_03237 3.64e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KODCOHLO_03238 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KODCOHLO_03239 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KODCOHLO_03240 6.67e-120 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
KODCOHLO_03242 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KODCOHLO_03243 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KODCOHLO_03244 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
KODCOHLO_03245 1.14e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KODCOHLO_03246 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
KODCOHLO_03247 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
KODCOHLO_03248 4.27e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KODCOHLO_03249 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KODCOHLO_03250 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
KODCOHLO_03251 6.24e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KODCOHLO_03252 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KODCOHLO_03253 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_03254 1.9e-138 yhzB - - S - - - B3/4 domain
KODCOHLO_03255 1.64e-284 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KODCOHLO_03256 1.64e-222 yhbB - - S - - - Putative amidase domain
KODCOHLO_03257 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KODCOHLO_03258 3.97e-140 yhbD - - K - - - Protein of unknown function (DUF4004)
KODCOHLO_03259 1.98e-85 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KODCOHLO_03260 1.91e-92 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KODCOHLO_03261 1.23e-07 - - - - - - - -
KODCOHLO_03262 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
KODCOHLO_03263 5.45e-279 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
KODCOHLO_03264 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
KODCOHLO_03265 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
KODCOHLO_03266 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
KODCOHLO_03267 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KODCOHLO_03268 1.41e-72 yhcC - - - - - - -
KODCOHLO_03269 8.21e-67 - - - - - - - -
KODCOHLO_03270 1.35e-80 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_03271 5.71e-159 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_03272 9.59e-215 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_03273 1.57e-209 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KODCOHLO_03274 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KODCOHLO_03275 6.29e-185 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KODCOHLO_03276 1.43e-234 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
KODCOHLO_03277 7.04e-306 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KODCOHLO_03278 4.59e-76 yhcM - - - - - - -
KODCOHLO_03279 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KODCOHLO_03280 5.61e-205 yhcP - - - - - - -
KODCOHLO_03281 1.22e-148 yhcQ - - M - - - Spore coat protein
KODCOHLO_03282 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KODCOHLO_03283 7.55e-136 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
KODCOHLO_03284 1.26e-213 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KODCOHLO_03285 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
KODCOHLO_03286 3.54e-90 yhcV - - S - - - COG0517 FOG CBS domain
KODCOHLO_03287 5.65e-160 yhcW - - S ko:K07025 - ko00000 hydrolase
KODCOHLO_03288 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KODCOHLO_03289 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KODCOHLO_03290 1.73e-133 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KODCOHLO_03291 2.32e-198 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KODCOHLO_03292 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KODCOHLO_03293 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KODCOHLO_03294 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
KODCOHLO_03295 1.97e-258 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
KODCOHLO_03296 4.47e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KODCOHLO_03297 1.39e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
KODCOHLO_03298 6.98e-53 yhdB - - S - - - YhdB-like protein
KODCOHLO_03299 1.46e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
KODCOHLO_03300 3.47e-296 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KODCOHLO_03301 7.66e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
KODCOHLO_03302 0.0 ygxB - - M - - - Conserved TM helix
KODCOHLO_03303 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
KODCOHLO_03304 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
KODCOHLO_03305 3.98e-171 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KODCOHLO_03306 1.16e-208 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_03307 2.33e-43 ynzC - - S - - - UPF0291 protein
KODCOHLO_03308 5.22e-145 yneB - - L - - - resolvase
KODCOHLO_03309 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KODCOHLO_03310 3.18e-141 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KODCOHLO_03312 3.58e-92 yndM - - S - - - Protein of unknown function (DUF2512)
KODCOHLO_03313 4.43e-185 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
KODCOHLO_03314 5e-11 - - - - - - - -
KODCOHLO_03315 3.09e-179 yndL - - S - - - Replication protein
KODCOHLO_03316 1.43e-100 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
KODCOHLO_03317 0.0 yobO - - M - - - Pectate lyase superfamily protein
KODCOHLO_03319 1.76e-122 yvgO - - - - - - -
KODCOHLO_03321 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KODCOHLO_03322 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
KODCOHLO_03323 2.69e-254 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KODCOHLO_03324 1.08e-149 - - - S - - - Domain of unknown function (DUF3885)
KODCOHLO_03325 3.99e-129 - - - J - - - Acetyltransferase (GNAT) domain
KODCOHLO_03326 1.74e-168 yoaP - - K - - - YoaP-like
KODCOHLO_03329 1.4e-235 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KODCOHLO_03334 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
KODCOHLO_03335 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
KODCOHLO_03337 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
KODCOHLO_03338 2.66e-270 xylR - - GK - - - ROK family
KODCOHLO_03339 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
KODCOHLO_03340 8.98e-316 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
KODCOHLO_03341 9.91e-265 mrjp - - G - - - Major royal jelly protein
KODCOHLO_03342 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KODCOHLO_03343 5.34e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
KODCOHLO_03344 1.67e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KODCOHLO_03345 2.7e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KODCOHLO_03346 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
KODCOHLO_03347 1.25e-147 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KODCOHLO_03348 6.15e-139 ymaB - - S - - - MutT family
KODCOHLO_03349 6.19e-239 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KODCOHLO_03350 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KODCOHLO_03351 9.34e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
KODCOHLO_03352 9.42e-29 ymzA - - - - - - -
KODCOHLO_03356 2.92e-29 - - - - - - - -
KODCOHLO_03358 5.1e-89 - - - S - - - HNH endonuclease
KODCOHLO_03359 1.12e-30 - - - - - - - -
KODCOHLO_03360 1.85e-110 - - - S - - - Phage terminase, small subunit
KODCOHLO_03361 1.58e-290 - - - S - - - Phage Terminase
KODCOHLO_03362 1.56e-14 - - - - - - - -
KODCOHLO_03363 5.35e-309 - - - S - - - Phage portal protein
KODCOHLO_03364 5.71e-145 - - - S - - - peptidase activity
KODCOHLO_03365 9.49e-282 - - - S - - - peptidase activity
KODCOHLO_03366 2.21e-07 - - - S - - - peptidoglycan catabolic process
KODCOHLO_03367 4.76e-59 - - - S - - - peptidoglycan catabolic process
KODCOHLO_03368 2.86e-31 - - - S - - - Phage gp6-like head-tail connector protein
KODCOHLO_03369 4.36e-20 - - - S - - - Phage head-tail joining protein
KODCOHLO_03370 8.87e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KODCOHLO_03371 8.17e-40 - - - - - - - -
KODCOHLO_03372 2.54e-76 - - - - - - - -
KODCOHLO_03373 4.7e-31 - - - - - - - -
KODCOHLO_03374 3.26e-19 - - - - - - - -
KODCOHLO_03375 0.0 - - - S - - - peptidoglycan catabolic process
KODCOHLO_03376 1.13e-140 - - - S - - - Phage tail protein
KODCOHLO_03377 1.79e-292 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
KODCOHLO_03378 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
KODCOHLO_03379 6.53e-229 - - - S - - - Domain of unknown function (DUF2479)
KODCOHLO_03382 5.36e-84 - - - S - - - Pfam:Phage_holin_4_1
KODCOHLO_03383 1.47e-87 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
KODCOHLO_03386 1.15e-30 - - - - - - - -
KODCOHLO_03389 3.73e-11 - - - - - - - -
KODCOHLO_03390 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KODCOHLO_03391 1.19e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
KODCOHLO_03392 2.41e-298 mlpA - - S - - - Belongs to the peptidase M16 family
KODCOHLO_03393 2.17e-56 ymxH - - S - - - YlmC YmxH family
KODCOHLO_03394 3.86e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
KODCOHLO_03395 1.93e-137 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KODCOHLO_03396 4.09e-248 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KODCOHLO_03397 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KODCOHLO_03398 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KODCOHLO_03399 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KODCOHLO_03400 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
KODCOHLO_03401 6.32e-42 - - - S - - - YlzJ-like protein
KODCOHLO_03402 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KODCOHLO_03403 2.59e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_03404 7.1e-293 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KODCOHLO_03407 3.32e-30 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KODCOHLO_03410 2.96e-209 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
KODCOHLO_03411 1.22e-89 - - - S - - - domain, Protein
KODCOHLO_03413 7.29e-40 - - - - - - - -
KODCOHLO_03414 6.95e-212 - - - S - - - AAA-like domain
KODCOHLO_03416 3.1e-30 yddH - - M - - - Lysozyme-like
KODCOHLO_03417 3.56e-48 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
KODCOHLO_03421 6.01e-111 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
KODCOHLO_03423 4.91e-89 - - - L - - - Protein of unknown function (DUF3991)
KODCOHLO_03427 2.88e-53 - - - K - - - COG0457 FOG TPR repeat
KODCOHLO_03428 3.1e-191 - - - - ko:K18640 - ko00000,ko04812 -
KODCOHLO_03434 5.13e-40 - - - - - - - -
KODCOHLO_03435 1.55e-195 - - - S - - - damaged DNA binding
KODCOHLO_03437 1.82e-41 csfB - - S - - - Inhibitor of sigma-G Gin
KODCOHLO_03438 4.86e-135 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KODCOHLO_03439 1.34e-241 yaaN - - P - - - Belongs to the TelA family
KODCOHLO_03440 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
KODCOHLO_03441 2.22e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KODCOHLO_03442 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
KODCOHLO_03443 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
KODCOHLO_03444 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KODCOHLO_03445 9e-189 yaaT - - S - - - stage 0 sporulation protein
KODCOHLO_03446 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
KODCOHLO_03447 8.05e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
KODCOHLO_03448 1.16e-62 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
KODCOHLO_03449 4.54e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KODCOHLO_03450 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
KODCOHLO_03451 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KODCOHLO_03452 2.49e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
KODCOHLO_03453 1.38e-307 yabE - - T - - - protein conserved in bacteria
KODCOHLO_03454 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KODCOHLO_03455 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KODCOHLO_03456 1.41e-209 yabG - - S ko:K06436 - ko00000 peptidase
KODCOHLO_03457 5.32e-53 veg - - S - - - protein conserved in bacteria
KODCOHLO_03458 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
KODCOHLO_03459 7.83e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KODCOHLO_03460 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KODCOHLO_03461 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
KODCOHLO_03462 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KODCOHLO_03463 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KODCOHLO_03464 2.47e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KODCOHLO_03465 7.21e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KODCOHLO_03466 1.74e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KODCOHLO_03467 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
KODCOHLO_03468 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KODCOHLO_03469 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
KODCOHLO_03470 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KODCOHLO_03471 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KODCOHLO_03472 1.42e-48 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KODCOHLO_03473 5.47e-66 yabP - - S - - - Sporulation protein YabP
KODCOHLO_03474 9.66e-134 yabQ - - S - - - spore cortex biosynthesis protein
KODCOHLO_03475 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KODCOHLO_03476 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KODCOHLO_03478 3.09e-89 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KODCOHLO_03479 1.82e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KODCOHLO_03480 9.81e-315 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
KODCOHLO_03481 2.39e-180 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KODCOHLO_03482 3.63e-219 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KODCOHLO_03483 8.24e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KODCOHLO_03484 8.01e-174 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
KODCOHLO_03485 1.45e-304 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
KODCOHLO_03486 1.9e-279 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KODCOHLO_03487 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KODCOHLO_03488 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_03489 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_03490 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_03492 2.64e-93 - - - L - - - Phage integrase family
KODCOHLO_03494 2.61e-91 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KODCOHLO_03495 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
KODCOHLO_03496 3.04e-198 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
KODCOHLO_03497 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
KODCOHLO_03498 2.83e-62 yokU - - S - - - YokU-like protein, putative antitoxin
KODCOHLO_03499 1e-47 yozE - - S - - - Belongs to the UPF0346 family
KODCOHLO_03500 6.07e-37 - - - E - - - lactoylglutathione lyase activity
KODCOHLO_03501 1.9e-161 yodN - - - - - - -
KODCOHLO_03503 9.77e-34 yozD - - S - - - YozD-like protein
KODCOHLO_03504 1.76e-132 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
KODCOHLO_03505 1.16e-72 yodL - - S - - - YodL-like
KODCOHLO_03507 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
KODCOHLO_03508 4.49e-192 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KODCOHLO_03509 2.5e-32 yodI - - - - - - -
KODCOHLO_03510 1.76e-165 yodH - - Q - - - Methyltransferase
KODCOHLO_03511 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KODCOHLO_03512 3.53e-169 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_03513 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KODCOHLO_03514 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
KODCOHLO_03515 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KODCOHLO_03516 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
KODCOHLO_03517 1.8e-220 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KODCOHLO_03518 2.84e-139 yahD - - S ko:K06999 - ko00000 Carboxylesterase
KODCOHLO_03519 1.35e-138 yodC - - C - - - nitroreductase
KODCOHLO_03520 2.42e-74 yodB - - K - - - transcriptional
KODCOHLO_03521 8.87e-89 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
KODCOHLO_03522 3.67e-89 iolK - - S - - - tautomerase
KODCOHLO_03524 1.91e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
KODCOHLO_03525 5.73e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
KODCOHLO_03526 1.05e-30 - - - - - - - -
KODCOHLO_03527 3.3e-79 yojF - - S - - - Protein of unknown function (DUF1806)
KODCOHLO_03528 2.24e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
KODCOHLO_03529 5.03e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KODCOHLO_03530 9.95e-303 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
KODCOHLO_03532 2.71e-143 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KODCOHLO_03533 1.11e-283 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
KODCOHLO_03534 5.58e-289 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KODCOHLO_03535 1.08e-143 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KODCOHLO_03536 1.2e-208 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
KODCOHLO_03537 0.0 yojO - - P - - - Von Willebrand factor
KODCOHLO_03538 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KODCOHLO_03539 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KODCOHLO_03540 5.88e-176 - - - S - - - Metallo-beta-lactamase superfamily
KODCOHLO_03541 2.23e-213 yocS - - S ko:K03453 - ko00000 -transporter
KODCOHLO_03542 1.45e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KODCOHLO_03543 9.6e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
KODCOHLO_03544 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
KODCOHLO_03545 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KODCOHLO_03546 1.35e-42 yozC - - - - - - -
KODCOHLO_03548 5.32e-75 yozO - - S - - - Bacterial PH domain
KODCOHLO_03549 6.36e-50 yocN - - - - - - -
KODCOHLO_03550 9.63e-60 yozN - - - - - - -
KODCOHLO_03551 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KODCOHLO_03553 1.92e-13 yocL - - - - - - -
KODCOHLO_03554 9.07e-79 yocK - - T - - - general stress protein
KODCOHLO_03556 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KODCOHLO_03559 6.92e-147 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
KODCOHLO_03562 4.53e-45 nucH 3.1.31.1 - L ko:K01174 - ko00000,ko01000 Staphylococcal nuclease homologues
KODCOHLO_03566 1.86e-110 - - - L - - - Domain of unknown function (DUF1738)
KODCOHLO_03571 3.71e-52 - - - L - - - Site-specific recombinase, phage integrase family
KODCOHLO_03574 1.06e-59 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KODCOHLO_03576 2.22e-13 rok - - S - - - Repressor of ComK
KODCOHLO_03578 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KODCOHLO_03579 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_03580 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_03581 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KODCOHLO_03582 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
KODCOHLO_03583 3.79e-291 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KODCOHLO_03584 3.51e-101 nucB - - M - - - Deoxyribonuclease NucA/NucB
KODCOHLO_03585 1.28e-152 yoaK - - S - - - Membrane
KODCOHLO_03586 7.97e-82 ymzB - - - - - - -
KODCOHLO_03587 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
KODCOHLO_03588 2.68e-161 ymaC - - S - - - Replication protein
KODCOHLO_03589 1.71e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
KODCOHLO_03590 3.04e-71 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KODCOHLO_03591 1.5e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KODCOHLO_03593 8.12e-75 ymaF - - S - - - YmaF family
KODCOHLO_03594 8.91e-220 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KODCOHLO_03595 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KODCOHLO_03596 7.65e-214 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KODCOHLO_03597 1.46e-160 yocH - - M - - - COG1388 FOG LysM repeat
KODCOHLO_03599 1.11e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
KODCOHLO_03600 3.78e-122 yocC - - - - - - -
KODCOHLO_03601 3.38e-179 - - - J - - - Protein required for attachment to host cells
KODCOHLO_03602 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
KODCOHLO_03603 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KODCOHLO_03604 2.58e-71 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
KODCOHLO_03605 2.24e-118 yobW - - - - - - -
KODCOHLO_03606 9.42e-173 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KODCOHLO_03607 1.35e-119 yobS - - K - - - Transcriptional regulator
KODCOHLO_03608 5.94e-78 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
KODCOHLO_03609 2.12e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
KODCOHLO_03610 5.86e-80 ykvN - - K - - - Transcriptional regulator
KODCOHLO_03611 5.8e-167 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KODCOHLO_03612 4.7e-57 - - - - - - - -
KODCOHLO_03613 6.1e-124 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KODCOHLO_03615 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KODCOHLO_03616 1.8e-247 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KODCOHLO_03617 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
KODCOHLO_03618 6.33e-261 yoaB - - EGP - - - the major facilitator superfamily
KODCOHLO_03619 4.6e-171 yoxB - - - - - - -
KODCOHLO_03620 2.6e-51 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KODCOHLO_03621 2.43e-157 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KODCOHLO_03622 8.08e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KODCOHLO_03623 3.42e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KODCOHLO_03624 9.42e-258 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KODCOHLO_03625 1.7e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_03626 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
KODCOHLO_03627 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KODCOHLO_03628 3.16e-233 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KODCOHLO_03629 8.7e-198 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
KODCOHLO_03630 4.79e-17 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KODCOHLO_03631 3.29e-67 - - - K - - - Helix-turn-helix domain
KODCOHLO_03632 1.13e-254 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
KODCOHLO_03633 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KODCOHLO_03634 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
KODCOHLO_03635 5.64e-125 - - - L - - - Integrase
KODCOHLO_03637 1.5e-124 yoeB - - S - - - IseA DL-endopeptidase inhibitor
KODCOHLO_03638 1.75e-310 yoeA - - V - - - MATE efflux family protein
KODCOHLO_03639 3.07e-236 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KODCOHLO_03640 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KODCOHLO_03641 2.36e-180 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KODCOHLO_03642 7.53e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
KODCOHLO_03643 6.4e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
KODCOHLO_03644 1.21e-209 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
KODCOHLO_03645 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
KODCOHLO_03646 9.47e-77 ypfA - - M - - - Flagellar protein YcgR
KODCOHLO_03647 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
KODCOHLO_03648 2.02e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KODCOHLO_03649 8.14e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KODCOHLO_03650 6.61e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KODCOHLO_03651 1.87e-12 - - - S - - - YpzI-like protein
KODCOHLO_03652 5.09e-135 yphA - - - - - - -
KODCOHLO_03653 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KODCOHLO_03654 1.41e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KODCOHLO_03655 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
KODCOHLO_03656 3.97e-172 yphF - - - - - - -
KODCOHLO_03657 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KODCOHLO_03658 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KODCOHLO_03659 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
KODCOHLO_03660 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KODCOHLO_03661 1.33e-175 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KODCOHLO_03662 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KODCOHLO_03663 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KODCOHLO_03664 2.86e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KODCOHLO_03665 1.96e-178 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
KODCOHLO_03666 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KODCOHLO_03667 1.11e-260 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KODCOHLO_03668 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KODCOHLO_03669 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KODCOHLO_03670 1.12e-209 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KODCOHLO_03671 1.59e-165 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
KODCOHLO_03672 1.68e-146 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
KODCOHLO_03673 1.42e-289 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KODCOHLO_03674 2.8e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KODCOHLO_03675 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KODCOHLO_03676 1.39e-257 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
KODCOHLO_03677 1.03e-303 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KODCOHLO_03678 7.18e-297 ypiA - - S - - - COG0457 FOG TPR repeat
KODCOHLO_03679 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
KODCOHLO_03680 1.94e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
KODCOHLO_03681 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
KODCOHLO_03682 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
KODCOHLO_03683 2.33e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
KODCOHLO_03684 2.17e-135 ypjA - - S - - - membrane
KODCOHLO_03687 2.01e-165 yibF - - S - - - YibE/F-like protein
KODCOHLO_03688 1.45e-158 frp - - C - - - nitroreductase
KODCOHLO_03689 3.14e-166 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
KODCOHLO_03690 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KODCOHLO_03691 4.49e-313 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KODCOHLO_03692 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
KODCOHLO_03693 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
KODCOHLO_03694 8.64e-106 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KODCOHLO_03695 4.9e-83 ydhN1 - - S - - - Domain of unknown function (DUF1992)
KODCOHLO_03696 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KODCOHLO_03697 1.17e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
KODCOHLO_03698 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KODCOHLO_03699 1.9e-177 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KODCOHLO_03700 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
KODCOHLO_03701 1.98e-26 yflI - - - - - - -
KODCOHLO_03702 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
KODCOHLO_03703 2.93e-157 yflK - - S - - - protein conserved in bacteria
KODCOHLO_03704 3.93e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KODCOHLO_03705 5.83e-277 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KODCOHLO_03706 1.34e-189 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KODCOHLO_03707 5.52e-285 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KODCOHLO_03708 7.99e-226 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
KODCOHLO_03709 9.33e-153 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KODCOHLO_03710 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KODCOHLO_03711 2.86e-96 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
KODCOHLO_03712 2.35e-18 - - - K - - - Transcriptional regulator
KODCOHLO_03715 4.4e-14 ywlA - - S - - - Uncharacterised protein family (UPF0715)
KODCOHLO_03716 2.81e-166 - - - - - - - -
KODCOHLO_03717 0.0 - - - Q ko:K15654 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 TIGRFAM amino acid adenylation domain
KODCOHLO_03718 9.03e-64 ynfC - - - - - - -
KODCOHLO_03719 3.14e-19 - - - - - - - -
KODCOHLO_03720 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KODCOHLO_03721 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KODCOHLO_03722 1.65e-88 yneT - - S ko:K06929 - ko00000 CoA-binding protein
KODCOHLO_03723 7.46e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KODCOHLO_03724 3.13e-65 yneR - - S - - - Belongs to the HesB IscA family
KODCOHLO_03725 3.18e-69 yneQ - - - - - - -
KODCOHLO_03726 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
KODCOHLO_03727 1e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
KODCOHLO_03729 3.46e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KODCOHLO_03730 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KODCOHLO_03731 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
KODCOHLO_03732 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
KODCOHLO_03733 2.44e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
KODCOHLO_03734 1.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
KODCOHLO_03735 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
KODCOHLO_03736 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
KODCOHLO_03737 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
KODCOHLO_03738 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
KODCOHLO_03739 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
KODCOHLO_03740 1.26e-105 yneE - - S - - - Sporulation inhibitor of replication protein sirA
KODCOHLO_03741 5.22e-49 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KODCOHLO_03744 6.64e-10 - - - S - - - YopX protein
KODCOHLO_03749 7.42e-102 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
KODCOHLO_03750 2.04e-167 yteA - - T - - - COG1734 DnaK suppressor protein
KODCOHLO_03751 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KODCOHLO_03752 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KODCOHLO_03753 5.94e-198 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KODCOHLO_03754 6.18e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KODCOHLO_03755 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KODCOHLO_03756 4.09e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KODCOHLO_03757 3.2e-33 - - - S - - - Domain of Unknown Function (DUF1540)
KODCOHLO_03758 2.23e-236 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KODCOHLO_03759 4.48e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KODCOHLO_03760 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KODCOHLO_03761 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KODCOHLO_03762 1.99e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
KODCOHLO_03763 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KODCOHLO_03764 1.48e-99 ytkA - - S - - - YtkA-like
KODCOHLO_03766 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KODCOHLO_03767 3.51e-79 ytkC - - S - - - Bacteriophage holin family
KODCOHLO_03768 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KODCOHLO_03769 4.35e-173 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KODCOHLO_03770 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KODCOHLO_03771 1.25e-236 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KODCOHLO_03772 1.35e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KODCOHLO_03773 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
KODCOHLO_03774 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KODCOHLO_03775 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KODCOHLO_03776 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KODCOHLO_03777 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KODCOHLO_03778 8.19e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KODCOHLO_03779 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
KODCOHLO_03780 9.59e-270 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
KODCOHLO_03781 1.67e-181 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
KODCOHLO_03782 1.26e-136 ytqB - - J - - - Putative rRNA methylase
KODCOHLO_03783 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
KODCOHLO_03784 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KODCOHLO_03785 1.84e-74 - - - - - - - -
KODCOHLO_03787 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_03788 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
KODCOHLO_03789 1.38e-84 yngL - - S - - - Protein of unknown function (DUF1360)
KODCOHLO_03790 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
KODCOHLO_03791 1.79e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KODCOHLO_03792 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KODCOHLO_03793 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
KODCOHLO_03794 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
KODCOHLO_03795 2.45e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
KODCOHLO_03796 2.48e-178 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
KODCOHLO_03797 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KODCOHLO_03798 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
KODCOHLO_03799 8.07e-203 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KODCOHLO_03800 7e-90 yngA - - S - - - membrane
KODCOHLO_03801 1.57e-184 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KODCOHLO_03802 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KODCOHLO_03803 1.08e-270 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KODCOHLO_03804 4.14e-164 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KODCOHLO_03805 6.5e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KODCOHLO_03806 2.58e-275 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KODCOHLO_03807 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
KODCOHLO_03808 8.91e-162 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KODCOHLO_03809 1.83e-156 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KODCOHLO_03810 1.6e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KODCOHLO_03811 5.22e-276 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KODCOHLO_03812 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_03814 7.21e-157 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
KODCOHLO_03815 3.88e-147 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
KODCOHLO_03816 1.01e-277 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
KODCOHLO_03817 2.9e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
KODCOHLO_03818 1.18e-109 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KODCOHLO_03819 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KODCOHLO_03820 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KODCOHLO_03821 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KODCOHLO_03822 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
KODCOHLO_03823 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
KODCOHLO_03825 3.02e-99 - - - L - - - Phage integrase family
KODCOHLO_03829 4.63e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KODCOHLO_03830 1.02e-235 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
KODCOHLO_03831 6.6e-181 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KODCOHLO_03832 1.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KODCOHLO_03833 2.67e-186 hemX - - O ko:K02497 - ko00000 cytochrome C
KODCOHLO_03834 1.02e-313 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KODCOHLO_03835 3.93e-114 ysxD - - - - - - -
KODCOHLO_03836 3.1e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KODCOHLO_03837 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KODCOHLO_03838 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
KODCOHLO_03839 3.83e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KODCOHLO_03840 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KODCOHLO_03841 2.25e-239 ysoA - - H - - - Tetratricopeptide repeat
KODCOHLO_03842 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KODCOHLO_03843 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KODCOHLO_03844 7.12e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KODCOHLO_03845 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KODCOHLO_03846 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KODCOHLO_03847 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KODCOHLO_03848 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KODCOHLO_03853 6.72e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
KODCOHLO_03854 4.55e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KODCOHLO_03855 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KODCOHLO_03856 2.58e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
KODCOHLO_03857 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KODCOHLO_03858 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
KODCOHLO_03859 3.95e-201 - - - L - - - Recombinase
KODCOHLO_03860 5.26e-09 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KODCOHLO_03862 2.29e-21 - - - - - - - -
KODCOHLO_03865 1.05e-60 - - - - - - - -
KODCOHLO_03867 7.59e-78 ydbB - - G - - - Cupin domain
KODCOHLO_03868 2.3e-76 ydbC - - S - - - Domain of unknown function (DUF4937
KODCOHLO_03869 7.8e-198 ydbD - - P ko:K07217 - ko00000 Catalase
KODCOHLO_03870 9.38e-256 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KODCOHLO_03871 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KODCOHLO_03872 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
KODCOHLO_03873 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KODCOHLO_03874 1.22e-230 ydbI - - S - - - AI-2E family transporter
KODCOHLO_03875 3.23e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KODCOHLO_03876 9.93e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KODCOHLO_03877 1.32e-69 ydbL - - - - - - -
KODCOHLO_03878 2.98e-260 ydbM - - I - - - acyl-CoA dehydrogenase
KODCOHLO_03879 1.13e-15 - - - S - - - Fur-regulated basic protein B
KODCOHLO_03880 6.58e-14 - - - S - - - Fur-regulated basic protein A
KODCOHLO_03881 1.91e-158 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KODCOHLO_03882 2.25e-74 ydbP - - CO - - - Thioredoxin
KODCOHLO_03883 2.16e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KODCOHLO_03884 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KODCOHLO_03885 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KODCOHLO_03886 5.73e-92 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
KODCOHLO_03887 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
KODCOHLO_03888 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
KODCOHLO_03889 4.42e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KODCOHLO_03890 6.39e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
KODCOHLO_03891 9.41e-278 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KODCOHLO_03892 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KODCOHLO_03893 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
KODCOHLO_03894 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
KODCOHLO_03895 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
KODCOHLO_03896 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KODCOHLO_03897 1.78e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
KODCOHLO_03898 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
KODCOHLO_03899 5.84e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KODCOHLO_03900 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KODCOHLO_03901 2.74e-139 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
KODCOHLO_03902 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
KODCOHLO_03903 1.78e-21 - - - - - - - -
KODCOHLO_03904 1.74e-75 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KODCOHLO_03910 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KODCOHLO_03911 7.16e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
KODCOHLO_03912 5.02e-228 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
KODCOHLO_03913 1.22e-87 cgeA - - - ko:K06319 - ko00000 -
KODCOHLO_03914 7.84e-61 cgeC - - - ko:K06321 - ko00000 -
KODCOHLO_03915 6.26e-307 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
KODCOHLO_03916 8.11e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
KODCOHLO_03918 7.1e-41 - - - L - - - Bacterial transcription activator, effector binding domain
KODCOHLO_03919 1.27e-307 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KODCOHLO_03920 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_03921 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_03922 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KODCOHLO_03923 2.22e-187 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
KODCOHLO_03924 3.19e-110 ypbF - - S - - - Protein of unknown function (DUF2663)
KODCOHLO_03925 5.57e-122 ypbE - - M - - - Lysin motif
KODCOHLO_03926 1.4e-127 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
KODCOHLO_03927 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KODCOHLO_03928 1.32e-247 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
KODCOHLO_03929 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
KODCOHLO_03930 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KODCOHLO_03931 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KODCOHLO_03932 5.07e-243 rsiX - - - - - - -
KODCOHLO_03933 1.77e-110 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KODCOHLO_03935 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KODCOHLO_03936 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
KODCOHLO_03937 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
KODCOHLO_03938 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KODCOHLO_03939 2.89e-273 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KODCOHLO_03940 1.08e-246 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KODCOHLO_03941 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
KODCOHLO_03942 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
KODCOHLO_03943 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KODCOHLO_03944 2.22e-278 pbpX - - V - - - Beta-lactamase
KODCOHLO_03945 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KODCOHLO_03946 1.55e-292 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KODCOHLO_03947 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KODCOHLO_03948 9.53e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
KODCOHLO_03949 3.14e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
KODCOHLO_03950 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
KODCOHLO_03951 4.1e-164 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KODCOHLO_03952 3.1e-305 ymfH - - S - - - zinc protease
KODCOHLO_03953 5.34e-305 albE - - S - - - Peptidase M16
KODCOHLO_03954 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
KODCOHLO_03955 9.55e-47 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KODCOHLO_03956 7.54e-40 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
KODCOHLO_03957 9.48e-43 - - - - - - - -
KODCOHLO_03959 9.45e-98 - - - CP - - - Membrane
KODCOHLO_03962 2.85e-07 - - - - - - - -
KODCOHLO_03970 4.48e-34 - - - - - - - -
KODCOHLO_03972 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KODCOHLO_03976 2.08e-128 - - - M - - - nucleic acid phosphodiester bond hydrolysis
KODCOHLO_03977 1.12e-38 - - - S - - - SMI1 / KNR4 family
KODCOHLO_03978 2.02e-161 - - - EGP - - - Necrosis inducing protein (NPP1)
KODCOHLO_03979 7.59e-51 - - - - - - - -
KODCOHLO_03980 5.89e-23 - - - - - - - -
KODCOHLO_03981 8.11e-38 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KODCOHLO_03982 2.27e-231 yaaC - - S - - - YaaC-like Protein
KODCOHLO_03983 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KODCOHLO_03984 9.38e-317 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KODCOHLO_03985 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KODCOHLO_03986 1.17e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KODCOHLO_03987 1.85e-284 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KODCOHLO_03988 2.58e-255 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KODCOHLO_03990 2.96e-08 - - - - - - - -
KODCOHLO_03992 2.86e-76 xkdS - - S - - - Protein of unknown function (DUF2634)
KODCOHLO_03993 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
KODCOHLO_03994 2.66e-206 xkdQ - - G - - - NLP P60 protein
KODCOHLO_03995 1.32e-144 xkdP - - S - - - Lysin motif
KODCOHLO_03996 5.56e-221 xkdO - - L - - - Transglycosylase SLT domain
KODCOHLO_03997 1.14e-187 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KODCOHLO_03998 9.42e-118 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
KODCOHLO_03999 1.43e-43 - - - - - - - -
KODCOHLO_04000 5.91e-184 - - - - - - - -
KODCOHLO_04001 4.54e-50 xkdW - - S - - - XkdW protein
KODCOHLO_04002 1.12e-22 xkdX - - - - - - -
KODCOHLO_04003 4.56e-150 xepA - - - - - - -
KODCOHLO_04004 8.29e-39 xhlA - - S - - - Haemolysin XhlA
KODCOHLO_04005 1.85e-40 xhlB - - S - - - SPP1 phage holin
KODCOHLO_04007 1.81e-50 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KODCOHLO_04008 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KODCOHLO_04009 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KODCOHLO_04010 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KODCOHLO_04011 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
KODCOHLO_04012 6.16e-63 ylxQ - - J - - - ribosomal protein
KODCOHLO_04013 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KODCOHLO_04014 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
KODCOHLO_04015 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KODCOHLO_04016 2.57e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KODCOHLO_04017 3.69e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KODCOHLO_04019 2.87e-63 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
KODCOHLO_04023 7.21e-281 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KODCOHLO_04024 8.91e-270 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
KODCOHLO_04025 4.48e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
KODCOHLO_04026 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
KODCOHLO_04027 9.78e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KODCOHLO_04028 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
KODCOHLO_04029 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KODCOHLO_04030 1.12e-286 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)