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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NBKGHOLO_00001	1.8e-104	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NBKGHOLO_00002	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NBKGHOLO_00003	1.4e-58	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
NBKGHOLO_00004	1.51e-279	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NBKGHOLO_00005	4.38e-222	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NBKGHOLO_00006	7.35e-249	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NBKGHOLO_00007	6.32e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NBKGHOLO_00008	0.0	ybeC	-	-	E	-	-	-	amino acid
NBKGHOLO_00009	2.21e-121	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
NBKGHOLO_00033	2.02e-83	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
NBKGHOLO_00034	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NBKGHOLO_00035	9.5e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NBKGHOLO_00036	6.48e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
NBKGHOLO_00037	4.31e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
NBKGHOLO_00038	8.78e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
NBKGHOLO_00039	2.35e-125	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NBKGHOLO_00040	6.18e-19	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NBKGHOLO_00041	9.92e-143	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NBKGHOLO_00042	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NBKGHOLO_00043	1.94e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NBKGHOLO_00044	2.41e-153	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
NBKGHOLO_00045	2.32e-238	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NBKGHOLO_00046	3.48e-73	-	-	-	-	-	-	-	-
NBKGHOLO_00047	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NBKGHOLO_00048	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NBKGHOLO_00049	2.39e-173	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NBKGHOLO_00050	1.24e-162	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
NBKGHOLO_00051	3.18e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBKGHOLO_00052	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
NBKGHOLO_00053	6.12e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NBKGHOLO_00054	2.2e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NBKGHOLO_00055	1.83e-119	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
NBKGHOLO_00056	8.13e-104	ytxH	-	-	S	-	-	-	YtxH-like protein
NBKGHOLO_00057	7.19e-40	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NBKGHOLO_00058	5.04e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NBKGHOLO_00059	1.97e-200	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
NBKGHOLO_00060	3.12e-110	ykuL	-	-	S	-	-	-	CBS domain
NBKGHOLO_00061	7.42e-172	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
NBKGHOLO_00062	2.24e-123	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NBKGHOLO_00063	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NBKGHOLO_00064	1.18e-109	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NBKGHOLO_00065	5.21e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NBKGHOLO_00066	1.2e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NBKGHOLO_00067	1.46e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NBKGHOLO_00068	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NBKGHOLO_00069	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NBKGHOLO_00070	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NBKGHOLO_00071	3.92e-87	cvpA	-	-	S	-	-	-	Colicin V production protein
NBKGHOLO_00072	3.45e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NBKGHOLO_00073	1.85e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NBKGHOLO_00074	3.12e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NBKGHOLO_00075	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NBKGHOLO_00076	9.14e-259	-	-	-	-	-	-	-	-
NBKGHOLO_00077	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NBKGHOLO_00078	1.2e-07	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NBKGHOLO_00079	1.66e-218	-	-	-	-	-	-	-	-
NBKGHOLO_00080	5.57e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NBKGHOLO_00081	4.12e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NBKGHOLO_00082	1.54e-305	ytoI	-	-	K	-	-	-	DRTGG domain
NBKGHOLO_00083	2.17e-265	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NBKGHOLO_00084	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NBKGHOLO_00085	1.45e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
NBKGHOLO_00086	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NBKGHOLO_00087	2.9e-85	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NBKGHOLO_00088	6.98e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NBKGHOLO_00089	2.16e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NBKGHOLO_00090	4.98e-250	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NBKGHOLO_00091	2.42e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NBKGHOLO_00092	1.25e-134	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
NBKGHOLO_00093	1.19e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NBKGHOLO_00094	3.84e-280	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NBKGHOLO_00095	5.25e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NBKGHOLO_00096	4.32e-148	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
NBKGHOLO_00097	9.91e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
NBKGHOLO_00098	1.84e-161	-	-	-	-	-	-	-	-
NBKGHOLO_00099	1.3e-201	dkgB	-	-	S	-	-	-	reductase
NBKGHOLO_00100	2.14e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NBKGHOLO_00101	2.81e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NBKGHOLO_00102	6.42e-101	-	-	-	K	-	-	-	Transcriptional regulator
NBKGHOLO_00103	5.26e-155	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
NBKGHOLO_00104	2.39e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NBKGHOLO_00105	2.66e-119	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NBKGHOLO_00106	1.03e-77	-	-	-	-	-	-	-	-
NBKGHOLO_00107	3.53e-227	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NBKGHOLO_00108	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NBKGHOLO_00109	1.05e-71	-	-	-	-	-	-	-	-
NBKGHOLO_00110	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
NBKGHOLO_00111	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
NBKGHOLO_00112	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NBKGHOLO_00113	6.46e-218	-	-	-	K	-	-	-	sequence-specific DNA binding
NBKGHOLO_00114	2.95e-123	-	-	-	-	-	-	-	-
NBKGHOLO_00115	1.6e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NBKGHOLO_00116	8.81e-218	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
NBKGHOLO_00117	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
NBKGHOLO_00118	6.96e-206	mleR	-	-	K	-	-	-	LysR family
NBKGHOLO_00119	8.59e-221	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NBKGHOLO_00120	2.41e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
NBKGHOLO_00121	1e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NBKGHOLO_00122	8.46e-177	-	-	-	-	-	-	-	-
NBKGHOLO_00123	9.06e-136	-	-	-	S	-	-	-	Flavin reductase like domain
NBKGHOLO_00124	3.6e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
NBKGHOLO_00125	1.81e-98	-	-	-	-	-	-	-	-
NBKGHOLO_00126	1e-129	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NBKGHOLO_00127	1.99e-36	-	-	-	-	-	-	-	-
NBKGHOLO_00128	5.52e-265	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
NBKGHOLO_00129	6.82e-104	-	-	-	-	-	-	-	-
NBKGHOLO_00130	5.83e-75	-	-	-	-	-	-	-	-
NBKGHOLO_00131	7.49e-237	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NBKGHOLO_00132	1.71e-64	-	-	-	-	-	-	-	-
NBKGHOLO_00133	5.89e-66	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NBKGHOLO_00134	6.52e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
NBKGHOLO_00135	7.15e-232	-	-	-	K	-	-	-	sequence-specific DNA binding
NBKGHOLO_00139	1.29e-07	rggD	-	-	K	-	-	-	Transcriptional regulator RggD
NBKGHOLO_00142	7.2e-260	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
NBKGHOLO_00143	1.19e-156	ydgI	-	-	C	-	-	-	Nitroreductase family
NBKGHOLO_00144	1.99e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
NBKGHOLO_00145	1.87e-307	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
NBKGHOLO_00146	3.55e-164	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
NBKGHOLO_00147	3.17e-11	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBKGHOLO_00148	1.59e-14	-	-	-	-	-	-	-	-
NBKGHOLO_00149	2.64e-94	-	-	-	S	-	-	-	GtrA-like protein
NBKGHOLO_00150	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
NBKGHOLO_00151	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
NBKGHOLO_00152	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NBKGHOLO_00153	2.27e-220	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NBKGHOLO_00154	4.78e-180	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_00155	1.68e-208	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NBKGHOLO_00156	3.27e-213	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_00157	3.73e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
NBKGHOLO_00159	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
NBKGHOLO_00160	2.6e-150	-	-	-	S	ko:K07118	-	ko00000	NmrA-like family
NBKGHOLO_00162	8.01e-254	-	-	-	-	-	-	-	-
NBKGHOLO_00163	3.18e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NBKGHOLO_00164	1.34e-115	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NBKGHOLO_00166	1.22e-155	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
NBKGHOLO_00167	5.27e-191	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NBKGHOLO_00168	1.59e-265	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
NBKGHOLO_00169	8.67e-111	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NBKGHOLO_00170	4.79e-21	-	-	-	-	-	-	-	-
NBKGHOLO_00171	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
NBKGHOLO_00172	4.96e-270	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NBKGHOLO_00173	4.36e-149	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
NBKGHOLO_00174	2.17e-180	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
NBKGHOLO_00175	6.59e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
NBKGHOLO_00176	1.85e-121	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
NBKGHOLO_00177	1.2e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
NBKGHOLO_00178	1.43e-224	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NBKGHOLO_00179	3.84e-161	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
NBKGHOLO_00180	8.15e-241	-	-	-	V	-	-	-	Beta-lactamase
NBKGHOLO_00181	1.91e-38	-	-	-	-	-	-	-	-
NBKGHOLO_00183	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NBKGHOLO_00184	2.13e-64	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00185	4.46e-91	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00187	5.59e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NBKGHOLO_00188	5.88e-213	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NBKGHOLO_00189	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NBKGHOLO_00190	3.63e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NBKGHOLO_00191	2.83e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NBKGHOLO_00193	8.62e-66	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NBKGHOLO_00194	1.33e-311	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NBKGHOLO_00195	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
NBKGHOLO_00196	5.46e-178	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
NBKGHOLO_00197	1.76e-174	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
NBKGHOLO_00198	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NBKGHOLO_00199	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
NBKGHOLO_00200	8.08e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NBKGHOLO_00201	8.94e-146	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
NBKGHOLO_00202	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
NBKGHOLO_00203	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NBKGHOLO_00204	2.68e-15	-	-	-	-	-	-	-	-
NBKGHOLO_00206	2.15e-195	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
NBKGHOLO_00207	3.15e-153	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
NBKGHOLO_00208	1.62e-226	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NBKGHOLO_00209	1.09e-310	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NBKGHOLO_00210	1.23e-200	-	-	-	C	-	-	-	nadph quinone reductase
NBKGHOLO_00211	1.72e-120	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
NBKGHOLO_00212	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
NBKGHOLO_00213	3.41e-144	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
NBKGHOLO_00214	5.46e-187	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NBKGHOLO_00215	7.73e-201	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_00216	5.16e-190	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
NBKGHOLO_00217	1.51e-89	-	-	-	K	-	-	-	LytTr DNA-binding domain
NBKGHOLO_00218	7.8e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NBKGHOLO_00219	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NBKGHOLO_00220	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
NBKGHOLO_00221	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NBKGHOLO_00222	1.02e-203	-	-	-	S	-	-	-	Aldo/keto reductase family
NBKGHOLO_00223	1.11e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
NBKGHOLO_00224	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NBKGHOLO_00225	1.95e-99	-	-	-	O	-	-	-	OsmC-like protein
NBKGHOLO_00226	3.02e-92	-	-	-	-	-	-	-	-
NBKGHOLO_00227	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NBKGHOLO_00228	2.98e-315	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NBKGHOLO_00229	3.78e-220	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
NBKGHOLO_00230	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
NBKGHOLO_00231	4.39e-273	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NBKGHOLO_00232	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NBKGHOLO_00233	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NBKGHOLO_00234	3.66e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
NBKGHOLO_00235	2.07e-281	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NBKGHOLO_00236	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_00237	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_00238	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NBKGHOLO_00239	5.32e-209	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
NBKGHOLO_00240	3.96e-187	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NBKGHOLO_00241	2.58e-101	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NBKGHOLO_00242	7.71e-185	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_00243	0.0	-	-	-	-	-	-	-	-
NBKGHOLO_00244	1.21e-211	yicL	-	-	EG	-	-	-	EamA-like transporter family
NBKGHOLO_00245	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
NBKGHOLO_00246	7.93e-151	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
NBKGHOLO_00247	2.63e-73	-	-	-	-	-	-	-	-
NBKGHOLO_00248	3.52e-163	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NBKGHOLO_00250	6.7e-304	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
NBKGHOLO_00251	3.8e-61	-	-	-	-	-	-	-	-
NBKGHOLO_00252	1.18e-228	-	-	-	S	-	-	-	Cell surface protein
NBKGHOLO_00253	3.31e-98	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NBKGHOLO_00254	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NBKGHOLO_00255	2.12e-173	-	-	-	-	-	-	-	-
NBKGHOLO_00256	9.6e-156	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_00257	1.61e-184	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NBKGHOLO_00258	1.94e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NBKGHOLO_00260	2.58e-179	-	-	-	-	-	-	-	-
NBKGHOLO_00262	1.27e-221	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NBKGHOLO_00263	9.58e-209	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NBKGHOLO_00264	4.03e-104	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NBKGHOLO_00265	2.09e-302	xylP	-	-	G	-	-	-	MFS/sugar transport protein
NBKGHOLO_00266	0.0	ycaM	-	-	E	-	-	-	amino acid
NBKGHOLO_00267	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NBKGHOLO_00268	8.65e-136	-	-	-	-	-	-	-	-
NBKGHOLO_00269	1.81e-252	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NBKGHOLO_00270	8.79e-208	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NBKGHOLO_00271	7.75e-258	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NBKGHOLO_00272	1.98e-163	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NBKGHOLO_00273	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NBKGHOLO_00274	2.47e-166	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NBKGHOLO_00275	1e-251	-	-	-	-	-	-	-	-
NBKGHOLO_00276	2.64e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NBKGHOLO_00277	9.54e-78	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NBKGHOLO_00278	4.95e-246	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NBKGHOLO_00279	1.52e-207	-	-	-	S	-	-	-	reductase
NBKGHOLO_00280	1.06e-96	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NBKGHOLO_00281	6.46e-290	-	-	-	E	-	-	-	Amino acid permease
NBKGHOLO_00282	5.06e-282	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
NBKGHOLO_00283	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase N-terminal domain
NBKGHOLO_00284	2.96e-101	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NBKGHOLO_00285	6.71e-135	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
NBKGHOLO_00286	3.54e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NBKGHOLO_00287	4.21e-120	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
NBKGHOLO_00288	1.98e-30	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
NBKGHOLO_00289	2.26e-245	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
NBKGHOLO_00290	1.69e-192	pbpE	-	-	V	-	-	-	Beta-lactamase
NBKGHOLO_00291	5.86e-61	-	-	-	-	-	-	-	-
NBKGHOLO_00292	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NBKGHOLO_00293	7.61e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
NBKGHOLO_00294	4.01e-44	-	-	-	-	-	-	-	-
NBKGHOLO_00296	8.67e-276	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
NBKGHOLO_00297	4.31e-97	-	-	-	L	-	-	-	Resolvase, N-terminal
NBKGHOLO_00298	2.19e-136	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NBKGHOLO_00299	8.1e-262	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
NBKGHOLO_00300	1.04e-64	yczG	-	-	K	-	-	-	Helix-turn-helix domain
NBKGHOLO_00301	1.52e-39	-	-	-	-	-	-	-	-
NBKGHOLO_00302	1.27e-37	-	-	-	L	-	-	-	RelB antitoxin
NBKGHOLO_00303	0.0	-	-	-	L	-	-	-	Exonuclease
NBKGHOLO_00307	2.52e-16	-	-	-	-	-	-	-	-
NBKGHOLO_00308	1.75e-100	-	-	-	O	-	-	-	OsmC-like protein
NBKGHOLO_00309	2e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
NBKGHOLO_00310	1.42e-133	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
NBKGHOLO_00311	1.22e-77	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
NBKGHOLO_00312	1.18e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NBKGHOLO_00313	1.61e-24	-	-	-	-	-	-	-	-
NBKGHOLO_00314	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NBKGHOLO_00315	2.77e-222	-	-	-	-	-	-	-	-
NBKGHOLO_00316	9.29e-250	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
NBKGHOLO_00317	2.12e-192	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NBKGHOLO_00322	1.35e-174	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
NBKGHOLO_00323	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NBKGHOLO_00324	5.03e-80	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NBKGHOLO_00325	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
NBKGHOLO_00326	3.49e-185	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NBKGHOLO_00327	2.05e-165	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NBKGHOLO_00328	8.14e-98	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NBKGHOLO_00329	1.8e-209	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NBKGHOLO_00330	8.23e-61	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
NBKGHOLO_00331	3.57e-192	-	-	-	S	-	-	-	hydrolase
NBKGHOLO_00332	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
NBKGHOLO_00333	1.22e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_00334	1.56e-235	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NBKGHOLO_00335	2.54e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NBKGHOLO_00336	1.98e-186	-	-	-	M	-	-	-	hydrolase, family 25
NBKGHOLO_00337	4.39e-25	-	-	-	S	-	-	-	YvrJ protein family
NBKGHOLO_00339	1.48e-163	-	-	-	-	-	-	-	-
NBKGHOLO_00340	1.84e-73	-	-	-	C	-	-	-	nitroreductase
NBKGHOLO_00341	1.74e-15	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NBKGHOLO_00342	8.41e-244	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00343	2.4e-92	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
NBKGHOLO_00344	1.67e-109	-	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
NBKGHOLO_00345	2.47e-233	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NBKGHOLO_00346	3.78e-42	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00347	6.54e-58	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00348	8.9e-83	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
NBKGHOLO_00349	8.71e-271	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00350	7.61e-240	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NBKGHOLO_00351	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00352	2.4e-80	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00353	4.07e-24	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
NBKGHOLO_00354	2.64e-218	-	3.2.1.122, 3.2.1.86	GH4,GT4	G	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
NBKGHOLO_00355	8.16e-108	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
NBKGHOLO_00356	4.05e-258	-	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NBKGHOLO_00357	2.92e-248	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
NBKGHOLO_00358	5.1e-144	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
NBKGHOLO_00359	3.92e-159	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
NBKGHOLO_00360	9.7e-211	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
NBKGHOLO_00361	4.75e-58	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00362	9.91e-87	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00363	2.17e-215	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NBKGHOLO_00364	4.54e-40	ptsN	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBKGHOLO_00365	8.13e-294	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
NBKGHOLO_00366	6.59e-291	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NBKGHOLO_00367	2.34e-264	bglP11	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NBKGHOLO_00368	1.74e-116	-	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
NBKGHOLO_00369	3.75e-65	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NBKGHOLO_00370	1.01e-56	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NBKGHOLO_00371	1.91e-11	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NBKGHOLO_00373	8.14e-48	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
NBKGHOLO_00374	1.25e-263	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NBKGHOLO_00375	4.21e-277	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
NBKGHOLO_00376	1.66e-84	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NBKGHOLO_00377	1.54e-166	-	-	-	S	-	-	-	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
NBKGHOLO_00378	3.37e-35	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NBKGHOLO_00379	3.85e-230	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NBKGHOLO_00380	8e-41	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00381	2.26e-72	gntR	-	-	K	-	-	-	rpiR family
NBKGHOLO_00382	2.12e-65	-	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NBKGHOLO_00383	1.82e-50	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
NBKGHOLO_00384	4.95e-39	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00385	1.47e-08	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00386	2.02e-236	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	iic component
NBKGHOLO_00388	1.88e-123	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
NBKGHOLO_00389	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
NBKGHOLO_00390	1.81e-295	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NBKGHOLO_00391	3.54e-57	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NBKGHOLO_00392	4.15e-312	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NBKGHOLO_00393	6.08e-192	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
NBKGHOLO_00394	1.02e-188	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NBKGHOLO_00395	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding cassette cobalt transporter
NBKGHOLO_00396	1.43e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
NBKGHOLO_00397	2.63e-203	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
NBKGHOLO_00398	3.95e-138	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
NBKGHOLO_00399	3.7e-217	-	-	-	C	-	-	-	FAD dependent oxidoreductase
NBKGHOLO_00400	7.42e-303	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	transporter
NBKGHOLO_00401	1.12e-189	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NBKGHOLO_00402	5.62e-191	manZ	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
NBKGHOLO_00403	1.64e-176	-	-	-	U	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NBKGHOLO_00404	1.65e-102	-	2.7.1.206	-	G	ko:K02813	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NBKGHOLO_00405	2.14e-81	-	2.7.1.206	-	G	ko:K02812	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NBKGHOLO_00406	6.9e-168	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
NBKGHOLO_00407	2.81e-209	-	-	-	K	-	-	-	sugar-binding domain protein
NBKGHOLO_00408	8.47e-304	-	-	-	E	ko:K19956	ko00051,map00051	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
NBKGHOLO_00409	0.0	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NBKGHOLO_00410	2.62e-198	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NBKGHOLO_00411	0.0	-	-	-	K	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00412	1.77e-198	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NBKGHOLO_00413	7.36e-159	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NBKGHOLO_00414	1.96e-117	fabG10	1.1.1.100, 1.3.1.28	-	IQ	ko:K00059,ko:K00216	ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
NBKGHOLO_00415	4.02e-223	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
NBKGHOLO_00416	4.36e-203	-	-	-	L	-	-	-	Integrase core domain
NBKGHOLO_00417	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
NBKGHOLO_00418	8.81e-49	-	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NBKGHOLO_00419	6.49e-111	-	-	-	G	-	-	-	DeoC/LacD family aldolase
NBKGHOLO_00420	7.44e-153	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
NBKGHOLO_00422	3.88e-271	dcuC	-	-	C	ko:K03326	-	ko00000,ko02000	Tripartite ATP-independent periplasmic transporter, DctM component
NBKGHOLO_00423	7.6e-199	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
NBKGHOLO_00424	1.1e-112	-	-	-	S	-	-	-	Zeta toxin
NBKGHOLO_00425	6.56e-192	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NBKGHOLO_00426	4.79e-63	-	-	-	-	-	-	-	-
NBKGHOLO_00427	4.22e-287	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NBKGHOLO_00428	1.27e-61	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00429	8.81e-204	-	-	-	GKT	-	-	-	transcriptional antiterminator
NBKGHOLO_00430	4.94e-40	-	-	-	-	-	-	-	-
NBKGHOLO_00431	7.11e-135	-	-	-	-	-	-	-	-
NBKGHOLO_00432	2.77e-89	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NBKGHOLO_00433	6.17e-177	-	-	-	EGP	-	-	-	Major Facilitator
NBKGHOLO_00434	4.33e-98	-	-	-	EGP	-	-	-	Major Facilitator
NBKGHOLO_00435	5.52e-121	-	-	-	-	-	-	-	-
NBKGHOLO_00436	7.7e-79	-	-	-	-	-	-	-	-
NBKGHOLO_00437	1.54e-103	-	-	-	-	-	-	-	-
NBKGHOLO_00438	9.81e-111	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NBKGHOLO_00439	3.66e-67	-	-	-	-	-	-	-	-
NBKGHOLO_00440	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
NBKGHOLO_00441	8.27e-183	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
NBKGHOLO_00446	7.37e-48	-	-	-	-	-	-	-	-
NBKGHOLO_00447	3.31e-58	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
NBKGHOLO_00448	2.71e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBKGHOLO_00449	1.13e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
NBKGHOLO_00450	2.36e-205	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NBKGHOLO_00451	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NBKGHOLO_00452	2.78e-80	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NBKGHOLO_00453	1.16e-239	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NBKGHOLO_00454	0.0	-	-	-	E	-	-	-	Amino acid permease
NBKGHOLO_00455	4.28e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NBKGHOLO_00456	5.6e-132	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NBKGHOLO_00457	7.84e-74	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NBKGHOLO_00458	6.35e-100	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NBKGHOLO_00459	1.46e-106	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
NBKGHOLO_00460	5.44e-163	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NBKGHOLO_00461	1.55e-141	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NBKGHOLO_00462	1.33e-311	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NBKGHOLO_00463	4.57e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NBKGHOLO_00464	3.19e-49	-	-	-	-	-	-	-	-
NBKGHOLO_00465	4.39e-34	-	-	-	-	-	-	-	-
NBKGHOLO_00466	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
NBKGHOLO_00468	5.5e-155	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
NBKGHOLO_00469	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NBKGHOLO_00470	1.3e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NBKGHOLO_00471	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00472	1.94e-246	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
NBKGHOLO_00473	3.76e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NBKGHOLO_00474	2.02e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00475	0.0	-	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBKGHOLO_00476	9.39e-256	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NBKGHOLO_00477	3.79e-293	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NBKGHOLO_00478	1.33e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
NBKGHOLO_00479	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NBKGHOLO_00480	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NBKGHOLO_00481	1.11e-84	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NBKGHOLO_00482	3.66e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NBKGHOLO_00483	2.07e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NBKGHOLO_00484	3.25e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NBKGHOLO_00485	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
NBKGHOLO_00486	5.31e-287	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NBKGHOLO_00487	1.15e-280	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
NBKGHOLO_00488	5.43e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
NBKGHOLO_00489	1.66e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NBKGHOLO_00490	1.31e-305	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NBKGHOLO_00491	1.34e-88	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00492	0.0	manR	-	-	G	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00493	1.74e-111	-	-	-	-	-	-	-	-
NBKGHOLO_00494	3.9e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NBKGHOLO_00495	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
NBKGHOLO_00496	1.81e-150	-	-	-	-	-	-	-	-
NBKGHOLO_00497	1.1e-197	-	-	-	-	-	-	-	-
NBKGHOLO_00498	4.73e-294	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NBKGHOLO_00499	3.11e-75	lacF-1	2.7.1.207	-	G	ko:K02786	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NBKGHOLO_00500	5.96e-185	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NBKGHOLO_00501	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
NBKGHOLO_00502	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NBKGHOLO_00503	4.22e-216	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NBKGHOLO_00504	3.14e-166	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
NBKGHOLO_00505	3.78e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NBKGHOLO_00506	2.32e-147	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NBKGHOLO_00507	1.12e-303	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBKGHOLO_00508	5.34e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NBKGHOLO_00509	2.83e-69	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
NBKGHOLO_00510	1.5e-151	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_00511	7.09e-179	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
NBKGHOLO_00512	8.13e-185	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
NBKGHOLO_00513	5.16e-192	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
NBKGHOLO_00514	4.62e-273	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
NBKGHOLO_00515	2.41e-96	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NBKGHOLO_00516	1.14e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
NBKGHOLO_00517	2.96e-57	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NBKGHOLO_00518	1.5e-178	ksgA	2.1.1.182, 2.1.1.197, 2.5.1.134	-	J	ko:K02169,ko:K02528,ko:K17216,ko:K17462	ko00270,ko00780,ko01100,ko01230,map00270,map00780,map01100,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	rRNA (adenine-N6,N6-)-dimethyltransferase activity
NBKGHOLO_00519	0.0	-	-	-	S	-	-	-	ABC transporter
NBKGHOLO_00520	2.04e-224	-	3.2.2.24	-	O	ko:K05521	-	ko00000,ko01000	ADP-ribosylglycohydrolase
NBKGHOLO_00521	4.32e-138	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NBKGHOLO_00522	4.9e-69	-	-	-	-	-	-	-	-
NBKGHOLO_00523	6.35e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
NBKGHOLO_00524	5.69e-189	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NBKGHOLO_00525	1.81e-172	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
NBKGHOLO_00526	4.98e-98	-	-	-	T	-	-	-	Sh3 type 3 domain protein
NBKGHOLO_00527	2.15e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NBKGHOLO_00528	6.87e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NBKGHOLO_00529	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NBKGHOLO_00530	3.89e-205	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
NBKGHOLO_00531	6.52e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NBKGHOLO_00532	2.96e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NBKGHOLO_00533	8.68e-169	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NBKGHOLO_00534	3.08e-74	-	-	-	-	-	-	-	-
NBKGHOLO_00535	4.61e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
NBKGHOLO_00536	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NBKGHOLO_00537	1.6e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
NBKGHOLO_00538	5.62e-190	gntR	-	-	K	-	-	-	rpiR family
NBKGHOLO_00539	2.1e-215	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
NBKGHOLO_00540	1.2e-203	-	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
NBKGHOLO_00541	1.75e-87	yodA	-	-	S	-	-	-	Tautomerase enzyme
NBKGHOLO_00542	5.48e-202	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NBKGHOLO_00543	2.99e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NBKGHOLO_00544	1.01e-250	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NBKGHOLO_00545	1.12e-245	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NBKGHOLO_00546	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NBKGHOLO_00547	6.58e-227	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NBKGHOLO_00548	1.64e-198	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NBKGHOLO_00549	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NBKGHOLO_00550	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NBKGHOLO_00551	3.88e-24	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	DeoR C terminal sensor domain
NBKGHOLO_00552	3.58e-146	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	DeoR C terminal sensor domain
NBKGHOLO_00553	1.93e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
NBKGHOLO_00554	1.83e-180	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NBKGHOLO_00555	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NBKGHOLO_00556	2.55e-111	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NBKGHOLO_00557	5.54e-303	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NBKGHOLO_00558	1.45e-280	hpk31	-	-	T	-	-	-	Histidine kinase
NBKGHOLO_00559	1.68e-156	vanR	-	-	K	-	-	-	response regulator
NBKGHOLO_00560	1.67e-152	-	-	-	-	-	-	-	-
NBKGHOLO_00561	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NBKGHOLO_00562	2.39e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NBKGHOLO_00563	7.71e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NBKGHOLO_00564	8.4e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NBKGHOLO_00565	6.39e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NBKGHOLO_00566	3.67e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
NBKGHOLO_00567	5.2e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NBKGHOLO_00568	9.03e-173	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NBKGHOLO_00569	2.32e-86	-	-	-	-	-	-	-	-
NBKGHOLO_00570	3.57e-165	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
NBKGHOLO_00572	1.89e-133	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
NBKGHOLO_00573	5.7e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NBKGHOLO_00574	3.25e-185	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
NBKGHOLO_00575	4.96e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
NBKGHOLO_00576	2.73e-166	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NBKGHOLO_00577	3.02e-87	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NBKGHOLO_00578	1.62e-80	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NBKGHOLO_00579	1.32e-39	-	-	-	-	-	-	-	-
NBKGHOLO_00580	1.68e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
NBKGHOLO_00581	1.55e-51	-	-	-	S	-	-	-	Transglycosylase associated protein
NBKGHOLO_00582	1.87e-93	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
NBKGHOLO_00583	5.78e-219	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBKGHOLO_00584	4.87e-37	-	-	-	-	-	-	-	-
NBKGHOLO_00585	4.57e-49	-	-	-	-	-	-	-	-
NBKGHOLO_00586	2.23e-107	-	-	-	C	-	-	-	Flavodoxin
NBKGHOLO_00587	7.43e-69	-	-	-	-	-	-	-	-
NBKGHOLO_00588	5.12e-84	-	-	-	-	-	-	-	-
NBKGHOLO_00589	1.47e-07	-	-	-	-	-	-	-	-
NBKGHOLO_00590	1.85e-73	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
NBKGHOLO_00591	2.86e-183	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
NBKGHOLO_00592	7.26e-273	-	-	-	S	ko:K06872	-	ko00000	TPM domain
NBKGHOLO_00593	6.18e-150	-	-	-	-	-	-	-	-
NBKGHOLO_00594	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NBKGHOLO_00595	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
NBKGHOLO_00596	2.66e-271	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
NBKGHOLO_00597	5.25e-106	-	-	-	S	-	-	-	NUDIX domain
NBKGHOLO_00598	2.2e-97	-	-	-	-	-	-	-	-
NBKGHOLO_00599	6.59e-151	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NBKGHOLO_00600	3.76e-161	-	-	-	-	-	-	-	-
NBKGHOLO_00601	1.92e-149	-	-	-	-	-	-	-	-
NBKGHOLO_00602	1.65e-116	-	-	-	-	-	-	-	-
NBKGHOLO_00603	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NBKGHOLO_00604	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NBKGHOLO_00606	3.79e-28	-	-	-	-	-	-	-	-
NBKGHOLO_00607	7.46e-61	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
NBKGHOLO_00609	1.4e-58	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
NBKGHOLO_00610	2.17e-179	-	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
NBKGHOLO_00611	3.47e-112	-	-	-	-	-	-	-	-
NBKGHOLO_00614	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
NBKGHOLO_00615	1.39e-174	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
NBKGHOLO_00616	3.89e-203	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NBKGHOLO_00617	1.27e-308	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NBKGHOLO_00618	9.14e-205	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NBKGHOLO_00619	0.0	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
NBKGHOLO_00620	3.65e-171	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NBKGHOLO_00621	1.7e-279	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NBKGHOLO_00622	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NBKGHOLO_00623	9.43e-73	-	-	-	-	-	-	-	-
NBKGHOLO_00624	4.92e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NBKGHOLO_00625	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
NBKGHOLO_00627	3.3e-240	ynjC	-	-	S	-	-	-	Cell surface protein
NBKGHOLO_00628	3.34e-176	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NBKGHOLO_00630	0.0	-	-	-	-	-	-	-	-
NBKGHOLO_00631	9.29e-138	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NBKGHOLO_00632	4.75e-57	-	-	-	-	-	-	-	-
NBKGHOLO_00633	2.25e-239	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NBKGHOLO_00634	3.44e-70	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
NBKGHOLO_00635	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NBKGHOLO_00636	2.83e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
NBKGHOLO_00637	1.17e-75	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
NBKGHOLO_00638	9.23e-55	-	-	-	-	-	-	-	-
NBKGHOLO_00639	3.38e-169	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
NBKGHOLO_00640	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NBKGHOLO_00641	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBKGHOLO_00642	3.35e-111	-	-	-	-	-	-	-	-
NBKGHOLO_00643	8.12e-69	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NBKGHOLO_00644	4.97e-64	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00645	6.21e-241	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBKGHOLO_00646	6.05e-118	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
NBKGHOLO_00647	4.14e-155	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
NBKGHOLO_00648	5.65e-255	yclK	-	-	T	-	-	-	Histidine kinase
NBKGHOLO_00649	4.54e-111	-	-	-	-	-	-	-	-
NBKGHOLO_00650	7.29e-290	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NBKGHOLO_00651	1.05e-143	-	-	-	-	-	-	-	-
NBKGHOLO_00652	1.06e-53	-	-	-	-	-	-	-	-
NBKGHOLO_00653	1.15e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NBKGHOLO_00654	2.67e-56	-	-	-	-	-	-	-	-
NBKGHOLO_00655	1.25e-264	mccF	-	-	V	-	-	-	LD-carboxypeptidase
NBKGHOLO_00656	2e-238	yveB	-	-	I	-	-	-	PAP2 superfamily
NBKGHOLO_00657	2.48e-142	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
NBKGHOLO_00658	3.4e-64	-	-	-	-	-	-	-	-
NBKGHOLO_00659	1.43e-38	-	-	-	-	-	-	-	-
NBKGHOLO_00660	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NBKGHOLO_00661	3.78e-131	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NBKGHOLO_00662	5.45e-154	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_00663	6.52e-36	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
NBKGHOLO_00664	1.34e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBKGHOLO_00665	7.11e-260	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
NBKGHOLO_00666	4.21e-72	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
NBKGHOLO_00667	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
NBKGHOLO_00668	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NBKGHOLO_00669	2.94e-264	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
NBKGHOLO_00670	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NBKGHOLO_00671	9.01e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_00672	8.13e-137	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NBKGHOLO_00673	6.9e-200	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NBKGHOLO_00674	8.98e-253	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
NBKGHOLO_00675	8.75e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NBKGHOLO_00676	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NBKGHOLO_00677	3.05e-282	-	-	-	-	-	-	-	-
NBKGHOLO_00678	3.57e-314	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NBKGHOLO_00679	4.7e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NBKGHOLO_00680	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NBKGHOLO_00681	3.17e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_00682	4.01e-99	-	-	-	P	-	-	-	ABC-2 family transporter protein
NBKGHOLO_00683	3.71e-68	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NBKGHOLO_00684	1.95e-78	-	-	-	K	-	-	-	Tetracyclin repressor, C-terminal all-alpha domain
NBKGHOLO_00685	2.4e-137	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
NBKGHOLO_00686	2.24e-64	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
NBKGHOLO_00688	4.24e-191	-	-	-	EG	-	-	-	EamA-like transporter family
NBKGHOLO_00689	2.62e-95	-	-	-	L	-	-	-	NUDIX domain
NBKGHOLO_00690	8.13e-82	-	-	-	-	-	-	-	-
NBKGHOLO_00691	5.83e-251	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NBKGHOLO_00692	5.72e-238	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NBKGHOLO_00693	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NBKGHOLO_00694	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NBKGHOLO_00695	1.03e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NBKGHOLO_00696	6.84e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NBKGHOLO_00697	3.74e-210	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBKGHOLO_00698	1.18e-174	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NBKGHOLO_00699	2.26e-136	-	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	dTDP-4-dehydrorhamnose 3,5-epimerase
NBKGHOLO_00701	5.06e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NBKGHOLO_00702	1.92e-135	-	-	-	-	-	-	-	-
NBKGHOLO_00703	1.39e-198	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
NBKGHOLO_00704	8.18e-151	-	-	-	-	-	-	-	-
NBKGHOLO_00705	6.02e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NBKGHOLO_00706	0.0	-	-	-	EGP	-	-	-	Major Facilitator
NBKGHOLO_00708	6.58e-231	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NBKGHOLO_00709	2.09e-170	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
NBKGHOLO_00710	2.84e-136	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
NBKGHOLO_00711	7.93e-290	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NBKGHOLO_00712	2.89e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NBKGHOLO_00714	5.67e-200	bglK_1	-	-	GK	-	-	-	ROK family
NBKGHOLO_00715	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NBKGHOLO_00716	1.01e-179	-	-	-	K	-	-	-	SIS domain
NBKGHOLO_00717	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
NBKGHOLO_00718	1.99e-104	frvA	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00719	0.0	-	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02770,ko:K02794,ko:K02795	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00720	2.81e-201	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NBKGHOLO_00722	2.13e-150	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
NBKGHOLO_00723	6.78e-132	dpsB	-	-	P	-	-	-	Belongs to the Dps family
NBKGHOLO_00724	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
NBKGHOLO_00725	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
NBKGHOLO_00726	7.45e-279	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_00727	2.13e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBKGHOLO_00728	1.96e-225	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NBKGHOLO_00730	1.68e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
NBKGHOLO_00731	1.3e-89	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
NBKGHOLO_00732	1.21e-309	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
NBKGHOLO_00733	2.75e-157	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
NBKGHOLO_00734	3.73e-137	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
NBKGHOLO_00735	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
NBKGHOLO_00737	9.32e-154	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NBKGHOLO_00738	2.81e-279	-	3.1.1.83	-	I	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	ko00000,ko00001,ko01000	Alpha beta hydrolase
NBKGHOLO_00739	1e-306	-	-	-	EGP	-	-	-	Major Facilitator
NBKGHOLO_00740	3.77e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
NBKGHOLO_00741	9.4e-76	ps105	-	-	-	-	-	-	-
NBKGHOLO_00742	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
NBKGHOLO_00743	1.74e-242	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
NBKGHOLO_00744	1.9e-163	kdgR	-	-	K	-	-	-	FCD domain
NBKGHOLO_00745	6.58e-293	-	-	-	G	-	-	-	Major Facilitator
NBKGHOLO_00746	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
NBKGHOLO_00747	0.0	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
NBKGHOLO_00748	4.1e-276	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
NBKGHOLO_00749	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
NBKGHOLO_00750	6.08e-227	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
NBKGHOLO_00751	5.06e-152	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
NBKGHOLO_00752	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
NBKGHOLO_00753	0.0	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
NBKGHOLO_00754	1.29e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
NBKGHOLO_00755	3.24e-158	azlC	-	-	E	-	-	-	branched-chain amino acid
NBKGHOLO_00756	3.76e-300	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
NBKGHOLO_00758	5.38e-68	-	-	-	-	-	-	-	-
NBKGHOLO_00759	3.12e-111	-	-	-	-	-	-	-	-
NBKGHOLO_00760	1.7e-142	-	-	-	S	-	-	-	Membrane
NBKGHOLO_00761	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NBKGHOLO_00763	7.34e-72	-	-	-	-	-	-	-	-
NBKGHOLO_00764	1.86e-146	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NBKGHOLO_00765	8.48e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NBKGHOLO_00766	1.58e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NBKGHOLO_00767	2.32e-60	-	-	-	-	-	-	-	-
NBKGHOLO_00768	2.94e-195	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NBKGHOLO_00769	6.57e-125	-	-	-	K	-	-	-	transcriptional regulator
NBKGHOLO_00770	3.54e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_00771	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NBKGHOLO_00772	3.23e-204	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
NBKGHOLO_00773	1.37e-269	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
NBKGHOLO_00774	9.89e-243	-	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
NBKGHOLO_00775	9.5e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_00776	1.95e-107	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
NBKGHOLO_00777	7.49e-138	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NBKGHOLO_00778	7.17e-39	-	-	-	-	-	-	-	-
NBKGHOLO_00779	2.05e-233	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
NBKGHOLO_00780	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
NBKGHOLO_00781	5.33e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NBKGHOLO_00782	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NBKGHOLO_00783	4.51e-127	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NBKGHOLO_00784	2.26e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NBKGHOLO_00785	8.99e-99	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NBKGHOLO_00786	5.66e-08	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NBKGHOLO_00790	6.04e-12	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NBKGHOLO_00791	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NBKGHOLO_00792	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NBKGHOLO_00793	3.29e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NBKGHOLO_00794	2.87e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
NBKGHOLO_00796	4.16e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NBKGHOLO_00797	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NBKGHOLO_00798	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NBKGHOLO_00801	1.56e-78	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NBKGHOLO_00802	8.28e-182	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NBKGHOLO_00803	3.01e-177	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
NBKGHOLO_00804	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NBKGHOLO_00805	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NBKGHOLO_00806	4.75e-89	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NBKGHOLO_00807	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
NBKGHOLO_00808	6.61e-41	-	-	-	-	-	-	-	-
NBKGHOLO_00810	3.65e-173	-	-	-	S	-	-	-	Putative threonine/serine exporter
NBKGHOLO_00811	1.8e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NBKGHOLO_00812	2.84e-284	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
NBKGHOLO_00815	4.1e-251	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
NBKGHOLO_00816	1.22e-76	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NBKGHOLO_00819	3.66e-190	-	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
NBKGHOLO_00820	5.63e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NBKGHOLO_00821	1.58e-285	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NBKGHOLO_00822	8.37e-308	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
NBKGHOLO_00823	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
NBKGHOLO_00824	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
NBKGHOLO_00825	4.93e-236	-	-	-	-	-	-	-	-
NBKGHOLO_00826	2.91e-39	-	-	-	-	-	-	-	-
NBKGHOLO_00827	3.85e-94	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBKGHOLO_00828	4.41e-113	-	-	-	C	-	-	-	nadph quinone reductase
NBKGHOLO_00829	3.88e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NBKGHOLO_00830	2.05e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_00831	1.77e-194	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBKGHOLO_00832	2.08e-283	-	-	-	K	-	-	-	IrrE N-terminal-like domain
NBKGHOLO_00833	1.23e-175	-	-	-	-	-	-	-	-
NBKGHOLO_00834	1.29e-25	-	-	-	-	-	-	-	-
NBKGHOLO_00835	7.2e-60	-	-	-	-	-	-	-	-
NBKGHOLO_00836	2.23e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NBKGHOLO_00837	2.92e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NBKGHOLO_00838	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00839	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
NBKGHOLO_00840	5.35e-102	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBKGHOLO_00841	1.75e-275	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
NBKGHOLO_00842	9.48e-237	lipA	-	-	I	-	-	-	Carboxylesterase family
NBKGHOLO_00843	2.32e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
NBKGHOLO_00844	3.77e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NBKGHOLO_00846	7.89e-216	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NBKGHOLO_00847	4.52e-169	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
NBKGHOLO_00848	3.93e-90	-	-	-	-	-	-	-	-
NBKGHOLO_00849	1.96e-192	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
NBKGHOLO_00851	3.32e-150	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBKGHOLO_00852	1.43e-123	-	-	-	-	-	-	-	-
NBKGHOLO_00853	4.99e-154	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
NBKGHOLO_00854	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
NBKGHOLO_00855	1.04e-289	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
NBKGHOLO_00856	1.12e-250	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
NBKGHOLO_00859	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
NBKGHOLO_00860	4.97e-272	-	-	-	M	-	-	-	Glycosyl transferases group 1
NBKGHOLO_00861	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
NBKGHOLO_00862	3.55e-172	-	-	-	S	-	-	-	Protein of unknown function DUF58
NBKGHOLO_00863	2.85e-215	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NBKGHOLO_00864	3.53e-134	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
NBKGHOLO_00865	1.33e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NBKGHOLO_00866	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_00867	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_00868	7.69e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_00869	7.03e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
NBKGHOLO_00870	8.69e-183	-	-	-	S	-	-	-	AAA ATPase domain
NBKGHOLO_00871	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
NBKGHOLO_00872	1.9e-104	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
NBKGHOLO_00873	9.87e-70	-	-	-	-	-	-	-	-
NBKGHOLO_00874	7.92e-76	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NBKGHOLO_00875	1.89e-167	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
NBKGHOLO_00876	3.97e-23	-	-	-	-	-	-	-	-
NBKGHOLO_00877	3.33e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NBKGHOLO_00878	7.62e-53	-	-	-	-	-	-	-	-
NBKGHOLO_00879	1.89e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_00880	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBKGHOLO_00881	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
NBKGHOLO_00886	5.07e-203	-	-	-	K	-	-	-	sequence-specific DNA binding
NBKGHOLO_00887	3.25e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBKGHOLO_00888	6.98e-241	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
NBKGHOLO_00889	2.8e-278	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NBKGHOLO_00890	7.73e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NBKGHOLO_00891	6.18e-173	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
NBKGHOLO_00892	7.33e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
NBKGHOLO_00893	1.54e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
NBKGHOLO_00894	7.35e-221	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
NBKGHOLO_00895	2.44e-269	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
NBKGHOLO_00896	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NBKGHOLO_00897	2.24e-146	ycaC	-	-	Q	-	-	-	Isochorismatase family
NBKGHOLO_00898	2.32e-115	-	-	-	S	-	-	-	AAA domain
NBKGHOLO_00899	1.02e-59	-	-	-	F	-	-	-	NUDIX domain
NBKGHOLO_00900	2.2e-22	-	-	-	F	-	-	-	NUDIX domain
NBKGHOLO_00901	5.23e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_00902	2.91e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
NBKGHOLO_00903	2.7e-68	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00904	8.04e-168	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NBKGHOLO_00905	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBKGHOLO_00906	3.7e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
NBKGHOLO_00907	4.59e-271	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
NBKGHOLO_00908	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NBKGHOLO_00909	3.99e-299	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NBKGHOLO_00910	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NBKGHOLO_00911	1.1e-159	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
NBKGHOLO_00912	5.24e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NBKGHOLO_00913	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NBKGHOLO_00914	0.0	yycH	-	-	S	-	-	-	YycH protein
NBKGHOLO_00915	1.49e-182	yycI	-	-	S	-	-	-	YycH protein
NBKGHOLO_00916	2.72e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NBKGHOLO_00917	1.99e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NBKGHOLO_00918	1.94e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NBKGHOLO_00919	4.09e-99	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
NBKGHOLO_00920	0.0	cadA	-	-	P	-	-	-	P-type ATPase
NBKGHOLO_00921	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase family 115
NBKGHOLO_00922	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NBKGHOLO_00923	0.0	bgaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NBKGHOLO_00924	9.87e-200	-	-	-	-	-	-	-	-
NBKGHOLO_00926	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NBKGHOLO_00927	5.64e-315	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
NBKGHOLO_00928	2.23e-134	-	-	-	-	-	-	-	-
NBKGHOLO_00929	7.69e-254	ysdE	-	-	P	-	-	-	Citrate transporter
NBKGHOLO_00930	1.18e-104	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NBKGHOLO_00931	1.33e-86	-	-	-	S	-	-	-	ASCH
NBKGHOLO_00932	1.69e-158	-	-	-	-	-	-	-	-
NBKGHOLO_00933	9.36e-111	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_00934	2.78e-170	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NBKGHOLO_00935	6.78e-100	-	-	-	E	-	-	-	HAD-hyrolase-like
NBKGHOLO_00936	8.86e-103	yfbM	-	-	K	-	-	-	FR47-like protein
NBKGHOLO_00937	5.69e-140	-	-	-	S	-	-	-	alpha beta
NBKGHOLO_00938	2.09e-48	-	-	-	-	-	-	-	-
NBKGHOLO_00939	1.5e-74	-	-	-	-	-	-	-	-
NBKGHOLO_00940	1.17e-178	-	-	-	V	-	-	-	ABC transporter transmembrane region
NBKGHOLO_00941	8.78e-08	-	-	-	S	-	-	-	SpoVT / AbrB like domain
NBKGHOLO_00942	2.34e-65	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
NBKGHOLO_00943	3.29e-182	-	-	-	Q	-	-	-	Methyltransferase
NBKGHOLO_00944	1.23e-96	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NBKGHOLO_00945	3.72e-202	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
NBKGHOLO_00946	7.62e-219	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NBKGHOLO_00947	1.76e-258	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
NBKGHOLO_00949	3.98e-172	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NBKGHOLO_00950	5.03e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NBKGHOLO_00951	5.58e-104	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NBKGHOLO_00952	5.24e-208	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NBKGHOLO_00953	1.47e-185	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NBKGHOLO_00954	2.54e-244	-	-	-	V	-	-	-	Beta-lactamase
NBKGHOLO_00955	1.69e-186	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NBKGHOLO_00956	7.56e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NBKGHOLO_00957	9.24e-269	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
NBKGHOLO_00958	2.51e-208	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
NBKGHOLO_00959	6.89e-191	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBKGHOLO_00960	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NBKGHOLO_00961	2.81e-90	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NBKGHOLO_00962	6.15e-170	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NBKGHOLO_00963	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NBKGHOLO_00964	2.68e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
NBKGHOLO_00965	2.06e-170	-	-	-	F	-	-	-	NUDIX domain
NBKGHOLO_00966	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
NBKGHOLO_00967	1.53e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
NBKGHOLO_00969	7.2e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
NBKGHOLO_00970	6.25e-117	-	-	-	K	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NBKGHOLO_00971	2.7e-246	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NBKGHOLO_00972	4.11e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
NBKGHOLO_00973	2.04e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
NBKGHOLO_00974	1.68e-310	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
NBKGHOLO_00975	3.03e-230	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
NBKGHOLO_00976	2.79e-199	-	-	-	GK	-	-	-	ROK family
NBKGHOLO_00977	5.44e-56	-	-	-	-	-	-	-	-
NBKGHOLO_00978	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NBKGHOLO_00979	2.97e-271	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
NBKGHOLO_00980	1.64e-103	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_00981	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NBKGHOLO_00982	3.93e-60	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_00983	1.51e-147	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
NBKGHOLO_00984	4.27e-176	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NBKGHOLO_00985	2.13e-212	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
NBKGHOLO_00986	3.56e-194	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NBKGHOLO_00987	1.83e-176	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NBKGHOLO_00988	6.82e-40	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
NBKGHOLO_00989	5.59e-33	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
NBKGHOLO_00990	4.82e-184	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
NBKGHOLO_00991	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
NBKGHOLO_00992	2.53e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
NBKGHOLO_00993	1.43e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
NBKGHOLO_00994	1.88e-252	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
NBKGHOLO_00995	1.74e-82	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NBKGHOLO_00996	2.41e-158	-	-	-	H	-	-	-	Pfam:Transaldolase
NBKGHOLO_00997	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NBKGHOLO_00998	1.33e-70	-	-	-	S	-	-	-	PRD domain
NBKGHOLO_00999	1.23e-80	-	-	-	S	-	-	-	Glycine-rich SFCGS
NBKGHOLO_01000	6.76e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
NBKGHOLO_01001	5.83e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
NBKGHOLO_01002	1.94e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
NBKGHOLO_01003	3.01e-275	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
NBKGHOLO_01004	3.41e-257	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
NBKGHOLO_01005	1.96e-177	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
NBKGHOLO_01007	9.61e-15	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NBKGHOLO_01008	2.22e-78	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NBKGHOLO_01009	3.33e-161	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NBKGHOLO_01010	6.58e-136	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
NBKGHOLO_01011	4.66e-259	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
NBKGHOLO_01012	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NBKGHOLO_01013	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
NBKGHOLO_01014	8.53e-65	araR	-	-	K	ko:K02103	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NBKGHOLO_01015	9.21e-30	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBKGHOLO_01016	2.21e-79	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NBKGHOLO_01017	5.55e-83	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NBKGHOLO_01018	9.75e-54	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NBKGHOLO_01019	1.43e-245	-	-	-	G	-	-	-	Melibiase
NBKGHOLO_01020	0.0	hylB	4.2.2.1	PL8	N	ko:K01727	-	ko00000,ko01000	Polysaccharide lyase family 8, N terminal alpha-helical domain
NBKGHOLO_01022	2.58e-156	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NBKGHOLO_01023	2.79e-192	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
NBKGHOLO_01024	6.85e-114	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
NBKGHOLO_01025	2.15e-175	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NBKGHOLO_01026	1.8e-181	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NBKGHOLO_01027	5.57e-141	-	-	-	K	-	-	-	Bacterial transcriptional regulator
NBKGHOLO_01028	1.8e-131	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NBKGHOLO_01029	7.7e-258	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
NBKGHOLO_01030	9.9e-105	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NBKGHOLO_01031	4.89e-172	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NBKGHOLO_01032	7.09e-184	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NBKGHOLO_01033	1.78e-86	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NBKGHOLO_01034	0.000638	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
NBKGHOLO_01035	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
NBKGHOLO_01036	6.74e-100	-	-	-	-	-	-	-	-
NBKGHOLO_01037	0.0	-	-	-	M	-	-	-	Right handed beta helix region
NBKGHOLO_01038	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NBKGHOLO_01039	5.54e-156	-	-	-	-	-	-	-	-
NBKGHOLO_01040	4.69e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NBKGHOLO_01041	5.2e-276	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
NBKGHOLO_01042	4.24e-247	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NBKGHOLO_01043	0.0	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
NBKGHOLO_01044	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NBKGHOLO_01045	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
NBKGHOLO_01046	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
NBKGHOLO_01047	6.22e-211	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NBKGHOLO_01049	5.58e-156	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
NBKGHOLO_01050	4.19e-89	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_01051	6.21e-68	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_01052	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NBKGHOLO_01054	1.22e-165	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
NBKGHOLO_01055	3.16e-312	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
NBKGHOLO_01056	1.95e-94	-	-	-	K	-	-	-	Transcriptional regulator
NBKGHOLO_01057	1.49e-97	-	-	-	-	-	-	-	-
NBKGHOLO_01058	1.15e-203	-	-	-	K	-	-	-	LysR substrate binding domain
NBKGHOLO_01059	2.69e-310	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
NBKGHOLO_01060	1.32e-132	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NBKGHOLO_01061	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NBKGHOLO_01062	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NBKGHOLO_01063	2.02e-168	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NBKGHOLO_01064	1.94e-216	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NBKGHOLO_01065	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBKGHOLO_01067	4.31e-115	-	-	-	-	-	-	-	-
NBKGHOLO_01068	5.11e-149	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NBKGHOLO_01069	3.1e-254	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NBKGHOLO_01070	5.18e-75	-	-	-	-	-	-	-	-
NBKGHOLO_01071	3.7e-60	-	-	-	-	-	-	-	-
NBKGHOLO_01072	4.76e-288	-	-	-	EK	-	-	-	Aminotransferase, class I
NBKGHOLO_01073	2.54e-212	-	-	-	K	-	-	-	LysR substrate binding domain
NBKGHOLO_01074	1.38e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NBKGHOLO_01075	4.01e-194	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NBKGHOLO_01076	3.55e-163	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
NBKGHOLO_01077	2.65e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NBKGHOLO_01078	1.71e-17	-	-	-	-	-	-	-	-
NBKGHOLO_01079	3.33e-78	-	-	-	-	-	-	-	-
NBKGHOLO_01080	5.39e-183	-	-	-	S	-	-	-	hydrolase
NBKGHOLO_01081	9.22e-246	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
NBKGHOLO_01082	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
NBKGHOLO_01083	4.69e-94	-	-	-	K	-	-	-	MarR family
NBKGHOLO_01084	1.13e-138	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NBKGHOLO_01085	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NBKGHOLO_01087	6.32e-141	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NBKGHOLO_01088	9.8e-167	ydfF	-	-	K	-	-	-	Transcriptional
NBKGHOLO_01089	1.22e-170	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_01090	5.4e-175	yadH	-	-	V	ko:K01992,ko:K09694	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
NBKGHOLO_01091	2.03e-225	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
NBKGHOLO_01092	4.46e-189	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
NBKGHOLO_01093	0.0	-	-	-	L	-	-	-	DNA helicase
NBKGHOLO_01094	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NBKGHOLO_01095	2.58e-226	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_01096	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
NBKGHOLO_01097	8.37e-90	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NBKGHOLO_01098	6.02e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NBKGHOLO_01099	5.07e-134	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NBKGHOLO_01100	6.41e-141	-	-	-	S	ko:K06872	-	ko00000	TPM domain
NBKGHOLO_01101	1.3e-302	dinF	-	-	V	-	-	-	MatE
NBKGHOLO_01102	6.53e-118	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NBKGHOLO_01103	2.94e-198	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
NBKGHOLO_01104	4.79e-222	ydhF	-	-	S	-	-	-	Aldo keto reductase
NBKGHOLO_01105	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NBKGHOLO_01106	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NBKGHOLO_01107	1e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NBKGHOLO_01108	3.46e-219	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NBKGHOLO_01109	3.78e-51	-	-	-	-	-	-	-	-
NBKGHOLO_01110	1.12e-125	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NBKGHOLO_01111	6.25e-217	-	-	-	-	-	-	-	-
NBKGHOLO_01113	3.42e-166	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
NBKGHOLO_01114	4.74e-139	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NBKGHOLO_01115	1.8e-217	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NBKGHOLO_01116	4.46e-118	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NBKGHOLO_01117	1.35e-193	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
NBKGHOLO_01118	8.68e-220	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NBKGHOLO_01119	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBKGHOLO_01120	3.43e-85	-	-	-	-	-	-	-	-
NBKGHOLO_01121	3.93e-41	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
NBKGHOLO_01122	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NBKGHOLO_01123	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NBKGHOLO_01124	3.2e-212	-	-	-	T	-	-	-	GHKL domain
NBKGHOLO_01125	1.23e-161	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NBKGHOLO_01126	3e-221	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
NBKGHOLO_01127	4.53e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
NBKGHOLO_01128	7.89e-105	manR	2.7.1.194, 2.7.1.200, 2.7.1.202	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBKGHOLO_01129	7.18e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NBKGHOLO_01130	5.35e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NBKGHOLO_01131	8e-197	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NBKGHOLO_01132	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
NBKGHOLO_01133	8.83e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NBKGHOLO_01134	6.67e-204	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NBKGHOLO_01135	1.38e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NBKGHOLO_01136	1.84e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_01137	1.01e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NBKGHOLO_01138	1.84e-281	ysaA	-	-	V	-	-	-	RDD family
NBKGHOLO_01139	3.01e-295	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NBKGHOLO_01140	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NBKGHOLO_01141	6.37e-67	nudA	-	-	S	-	-	-	ASCH
NBKGHOLO_01142	1.16e-95	-	-	-	-	-	-	-	-
NBKGHOLO_01143	1.4e-78	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NBKGHOLO_01144	3.18e-239	-	-	-	S	-	-	-	DUF218 domain
NBKGHOLO_01145	1.53e-107	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NBKGHOLO_01146	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
NBKGHOLO_01147	2.07e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
NBKGHOLO_01148	1.21e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NBKGHOLO_01149	3.09e-103	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NBKGHOLO_01150	4.99e-194	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NBKGHOLO_01152	2.23e-279	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NBKGHOLO_01153	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NBKGHOLO_01154	6.15e-06	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBKGHOLO_01155	8.05e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBKGHOLO_01157	1.85e-08	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBKGHOLO_01158	3.31e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NBKGHOLO_01159	3.24e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NBKGHOLO_01160	2.69e-95	-	-	-	-	-	-	-	-
NBKGHOLO_01161	4.49e-159	-	-	-	-	-	-	-	-
NBKGHOLO_01162	1.11e-158	-	-	-	S	-	-	-	Tetratricopeptide repeat
NBKGHOLO_01163	1.77e-189	-	-	-	-	-	-	-	-
NBKGHOLO_01164	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NBKGHOLO_01165	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NBKGHOLO_01166	2.25e-83	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NBKGHOLO_01167	2.9e-276	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NBKGHOLO_01168	5.46e-51	-	-	-	-	-	-	-	-
NBKGHOLO_01169	2.32e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NBKGHOLO_01171	1.33e-111	queT	-	-	S	-	-	-	QueT transporter
NBKGHOLO_01172	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
NBKGHOLO_01173	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NBKGHOLO_01174	1.69e-167	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NBKGHOLO_01175	1.9e-154	-	-	-	S	-	-	-	(CBS) domain
NBKGHOLO_01176	3.35e-148	-	-	-	S	-	-	-	Flavodoxin-like fold
NBKGHOLO_01177	0.0	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
NBKGHOLO_01178	2.6e-124	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NBKGHOLO_01179	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NBKGHOLO_01180	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NBKGHOLO_01181	1.05e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NBKGHOLO_01182	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NBKGHOLO_01183	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NBKGHOLO_01184	2.33e-52	yabO	-	-	J	-	-	-	S4 domain protein
NBKGHOLO_01185	1.87e-84	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
NBKGHOLO_01186	8.3e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
NBKGHOLO_01187	9.66e-308	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NBKGHOLO_01188	2.04e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NBKGHOLO_01189	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NBKGHOLO_01190	4.9e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NBKGHOLO_01191	1.12e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NBKGHOLO_01192	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NBKGHOLO_01199	7.17e-104	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NBKGHOLO_01200	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NBKGHOLO_01201	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBKGHOLO_01202	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBKGHOLO_01203	2.84e-109	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
NBKGHOLO_01204	3.06e-44	-	-	-	M	-	-	-	domain protein
NBKGHOLO_01205	0.0	-	-	-	M	-	-	-	domain protein
NBKGHOLO_01206	3.18e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NBKGHOLO_01207	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NBKGHOLO_01208	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NBKGHOLO_01209	4.99e-252	-	-	-	K	-	-	-	WYL domain
NBKGHOLO_01210	5.85e-139	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
NBKGHOLO_01211	1.26e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
NBKGHOLO_01212	1.09e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NBKGHOLO_01213	1.4e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NBKGHOLO_01214	3.43e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NBKGHOLO_01215	5.07e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NBKGHOLO_01216	2.07e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NBKGHOLO_01217	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NBKGHOLO_01218	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NBKGHOLO_01219	2.92e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NBKGHOLO_01220	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NBKGHOLO_01221	4.53e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NBKGHOLO_01222	9.86e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NBKGHOLO_01223	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NBKGHOLO_01224	1.67e-66	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NBKGHOLO_01225	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NBKGHOLO_01226	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NBKGHOLO_01227	3.7e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NBKGHOLO_01228	5.63e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NBKGHOLO_01229	8.15e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NBKGHOLO_01230	1.83e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NBKGHOLO_01231	1.42e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NBKGHOLO_01232	1.63e-297	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NBKGHOLO_01233	3.86e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NBKGHOLO_01234	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NBKGHOLO_01235	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NBKGHOLO_01236	2.66e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NBKGHOLO_01237	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NBKGHOLO_01238	1.8e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBKGHOLO_01239	2.94e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NBKGHOLO_01240	3.39e-148	-	-	-	-	-	-	-	-
NBKGHOLO_01241	2.32e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBKGHOLO_01242	7.13e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBKGHOLO_01243	5.43e-185	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBKGHOLO_01244	3.99e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NBKGHOLO_01245	3.52e-175	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
NBKGHOLO_01246	1.28e-45	-	-	-	-	-	-	-	-
NBKGHOLO_01247	7.1e-162	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NBKGHOLO_01248	7.16e-236	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NBKGHOLO_01249	2.05e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NBKGHOLO_01250	4.23e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NBKGHOLO_01251	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NBKGHOLO_01252	4.36e-265	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NBKGHOLO_01253	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NBKGHOLO_01254	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NBKGHOLO_01256	3.92e-28	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NBKGHOLO_01258	1.06e-156	-	-	-	S	-	-	-	B3/4 domain
NBKGHOLO_01259	6.12e-190	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NBKGHOLO_01260	5.81e-155	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NBKGHOLO_01261	5.68e-298	-	-	-	I	-	-	-	Acyltransferase family
NBKGHOLO_01262	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
NBKGHOLO_01263	2.26e-218	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
NBKGHOLO_01264	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase concanavalin-like domain
NBKGHOLO_01265	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NBKGHOLO_01266	5.96e-87	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NBKGHOLO_01267	1.91e-69	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NBKGHOLO_01269	2.99e-27	-	-	-	-	-	-	-	-
NBKGHOLO_01270	5.73e-209	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NBKGHOLO_01271	7.54e-113	-	-	-	-	-	-	-	-
NBKGHOLO_01272	1.4e-152	-	-	-	GM	-	-	-	NmrA-like family
NBKGHOLO_01273	2.35e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NBKGHOLO_01274	8.32e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NBKGHOLO_01275	1.61e-168	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NBKGHOLO_01276	9.44e-186	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NBKGHOLO_01277	1.55e-224	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NBKGHOLO_01278	1.68e-67	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NBKGHOLO_01279	2.4e-144	-	-	-	P	-	-	-	Cation efflux family
NBKGHOLO_01280	2.5e-34	-	-	-	-	-	-	-	-
NBKGHOLO_01281	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
NBKGHOLO_01282	1.61e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NBKGHOLO_01283	4.42e-84	-	-	-	-	-	-	-	-
NBKGHOLO_01284	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NBKGHOLO_01285	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NBKGHOLO_01286	7.48e-25	-	-	-	-	-	-	-	-
NBKGHOLO_01287	2.58e-171	-	-	-	-	-	-	-	-
NBKGHOLO_01288	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NBKGHOLO_01289	5.39e-32	-	-	-	S	-	-	-	Short C-terminal domain
NBKGHOLO_01290	1.61e-274	yqiG	-	-	C	-	-	-	Oxidoreductase
NBKGHOLO_01291	1.81e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NBKGHOLO_01292	3.98e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
NBKGHOLO_01293	1.59e-71	-	-	-	S	-	-	-	Enterocin A Immunity
NBKGHOLO_01294	1.05e-70	-	-	-	-	-	-	-	-
NBKGHOLO_01295	0.0	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
NBKGHOLO_01296	2.35e-91	-	-	-	K	-	-	-	Transcriptional regulator
NBKGHOLO_01297	8.4e-170	-	-	-	S	-	-	-	CAAX protease self-immunity
NBKGHOLO_01301	1.59e-30	-	-	-	-	-	-	-	-
NBKGHOLO_01302	1.3e-59	-	-	-	S	-	-	-	Enterocin A Immunity
NBKGHOLO_01303	1.58e-170	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NBKGHOLO_01304	6.83e-179	comD	2.7.13.3	-	T	ko:K07706,ko:K12294	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NBKGHOLO_01305	5.87e-84	comD	2.7.13.3	-	T	ko:K07706,ko:K12294	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NBKGHOLO_01307	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NBKGHOLO_01308	3.87e-301	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
NBKGHOLO_01309	5.9e-78	-	-	-	-	-	-	-	-
NBKGHOLO_01310	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
NBKGHOLO_01311	7.94e-156	tas	-	-	C	-	-	-	Aldo/keto reductase family
NBKGHOLO_01312	1.23e-58	-	-	-	S	-	-	-	Enterocin A Immunity
NBKGHOLO_01313	1.93e-170	-	-	-	-	-	-	-	-
NBKGHOLO_01314	5.59e-176	-	-	-	-	-	-	-	-
NBKGHOLO_01315	5.62e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
NBKGHOLO_01316	9.02e-125	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBKGHOLO_01317	4.88e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
NBKGHOLO_01318	4.38e-285	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NBKGHOLO_01319	4.45e-133	-	-	-	-	-	-	-	-
NBKGHOLO_01320	0.0	-	-	-	M	-	-	-	domain protein
NBKGHOLO_01321	0.0	-	-	-	M	-	-	-	domain protein
NBKGHOLO_01322	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
NBKGHOLO_01323	1.16e-179	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NBKGHOLO_01325	6.62e-69	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_01326	3.66e-36	-	-	-	V	-	-	-	MacB-like periplasmic core domain
NBKGHOLO_01327	3.96e-120	-	-	-	-	-	-	-	-
NBKGHOLO_01329	7.99e-189	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NBKGHOLO_01330	5.56e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NBKGHOLO_01331	4.93e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NBKGHOLO_01332	4.69e-46	-	-	-	-	-	-	-	-
NBKGHOLO_01333	2.13e-44	-	-	-	-	-	-	-	-
NBKGHOLO_01335	9.32e-118	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
NBKGHOLO_01336	3.92e-218	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
NBKGHOLO_01337	4.06e-146	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
NBKGHOLO_01338	3.49e-242	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
NBKGHOLO_01339	9.56e-189	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NBKGHOLO_01340	9.49e-26	-	-	-	S	-	-	-	CsbD-like
NBKGHOLO_01341	2.43e-264	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NBKGHOLO_01342	5.45e-61	-	-	-	-	-	-	-	-
NBKGHOLO_01343	1.1e-256	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
NBKGHOLO_01344	9.8e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NBKGHOLO_01345	2.36e-119	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
NBKGHOLO_01346	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
NBKGHOLO_01347	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NBKGHOLO_01348	2.55e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NBKGHOLO_01349	7.65e-272	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NBKGHOLO_01350	1.42e-249	-	-	-	-	-	-	-	-
NBKGHOLO_01351	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NBKGHOLO_01352	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NBKGHOLO_01353	2.37e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NBKGHOLO_01354	4.49e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
NBKGHOLO_01355	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NBKGHOLO_01356	1.06e-258	yacL	-	-	S	-	-	-	domain protein
NBKGHOLO_01357	1.12e-138	-	-	-	K	-	-	-	sequence-specific DNA binding
NBKGHOLO_01358	9.79e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_01359	6.42e-88	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NBKGHOLO_01360	6.07e-292	inlJ	-	-	M	-	-	-	MucBP domain
NBKGHOLO_01361	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NBKGHOLO_01362	3.54e-82	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
NBKGHOLO_01363	3.09e-223	-	-	-	S	-	-	-	Membrane
NBKGHOLO_01364	1.36e-179	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
NBKGHOLO_01365	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NBKGHOLO_01367	5.16e-127	-	-	-	-	-	-	-	-
NBKGHOLO_01368	4.31e-312	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
NBKGHOLO_01369	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NBKGHOLO_01370	2.3e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NBKGHOLO_01371	2.6e-185	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBKGHOLO_01372	1.45e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
NBKGHOLO_01373	3.64e-249	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
NBKGHOLO_01374	2.58e-155	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
NBKGHOLO_01375	4.05e-247	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NBKGHOLO_01376	2.02e-273	-	-	-	-	-	-	-	-
NBKGHOLO_01377	3.67e-196	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NBKGHOLO_01378	1.29e-202	-	-	-	-	-	-	-	-
NBKGHOLO_01379	5.81e-125	-	-	-	-	-	-	-	-
NBKGHOLO_01380	3.41e-187	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NBKGHOLO_01381	9.18e-105	-	-	-	-	-	-	-	-
NBKGHOLO_01382	9.42e-232	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NBKGHOLO_01383	7.23e-128	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
NBKGHOLO_01384	2.87e-106	-	-	-	S	-	-	-	NusG domain II
NBKGHOLO_01385	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NBKGHOLO_01386	7.5e-190	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
NBKGHOLO_01387	1.15e-280	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
NBKGHOLO_01388	3.78e-248	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NBKGHOLO_01390	7.19e-209	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
NBKGHOLO_01391	2.18e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NBKGHOLO_01392	3.75e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NBKGHOLO_01393	2.53e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NBKGHOLO_01394	8e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NBKGHOLO_01395	1.64e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NBKGHOLO_01396	6.51e-103	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
NBKGHOLO_01397	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
NBKGHOLO_01398	2.89e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
NBKGHOLO_01399	5.8e-113	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
NBKGHOLO_01400	5.42e-117	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
NBKGHOLO_01401	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NBKGHOLO_01402	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
NBKGHOLO_01403	1.97e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NBKGHOLO_01404	1.12e-124	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NBKGHOLO_01405	4.45e-122	yqaB	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_01406	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NBKGHOLO_01407	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NBKGHOLO_01408	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NBKGHOLO_01410	1.03e-281	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
NBKGHOLO_01411	2.4e-117	-	-	-	-	-	-	-	-
NBKGHOLO_01412	5.9e-193	-	-	-	K	-	-	-	acetyltransferase
NBKGHOLO_01413	1.04e-287	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NBKGHOLO_01414	6.19e-109	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NBKGHOLO_01415	4.57e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NBKGHOLO_01416	1.62e-199	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NBKGHOLO_01417	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NBKGHOLO_01418	1.22e-220	ccpB	-	-	K	-	-	-	lacI family
NBKGHOLO_01419	7.81e-88	-	-	-	-	-	-	-	-
NBKGHOLO_01420	2.27e-89	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
NBKGHOLO_01421	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NBKGHOLO_01422	3.34e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
NBKGHOLO_01423	5.69e-65	-	-	-	-	-	-	-	-
NBKGHOLO_01424	5.13e-113	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NBKGHOLO_01425	9.72e-289	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NBKGHOLO_01426	2.82e-71	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NBKGHOLO_01427	2.29e-50	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NBKGHOLO_01428	2.17e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NBKGHOLO_01429	1.35e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NBKGHOLO_01430	2.6e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NBKGHOLO_01431	2.31e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
NBKGHOLO_01432	2.38e-225	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NBKGHOLO_01433	2.27e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NBKGHOLO_01434	1.56e-194	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NBKGHOLO_01435	4.51e-184	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NBKGHOLO_01436	8.71e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
NBKGHOLO_01437	4.02e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
NBKGHOLO_01438	7.32e-153	-	-	-	-	-	-	-	-
NBKGHOLO_01439	3.82e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
NBKGHOLO_01440	1.06e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
NBKGHOLO_01441	4.36e-240	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NBKGHOLO_01442	6.92e-66	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NBKGHOLO_01443	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NBKGHOLO_01444	7.76e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NBKGHOLO_01445	7.06e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NBKGHOLO_01446	1.39e-202	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_01447	1.3e-240	-	-	-	-	-	-	-	-
NBKGHOLO_01448	8.28e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NBKGHOLO_01449	3.53e-142	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NBKGHOLO_01450	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NBKGHOLO_01451	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NBKGHOLO_01452	7.56e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
NBKGHOLO_01453	0.0	ydaO	-	-	E	-	-	-	amino acid
NBKGHOLO_01454	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NBKGHOLO_01455	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NBKGHOLO_01456	1.49e-125	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
NBKGHOLO_01457	1.86e-108	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NBKGHOLO_01458	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NBKGHOLO_01459	5.61e-253	-	-	-	I	-	-	-	Acyltransferase
NBKGHOLO_01460	2.69e-185	-	-	-	S	-	-	-	Alpha beta hydrolase
NBKGHOLO_01461	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
NBKGHOLO_01462	7.41e-175	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
NBKGHOLO_01463	2.53e-147	-	-	-	F	-	-	-	glutamine amidotransferase
NBKGHOLO_01464	1.07e-141	-	-	-	T	-	-	-	Sh3 type 3 domain protein
NBKGHOLO_01465	1.81e-132	-	-	-	Q	-	-	-	methyltransferase
NBKGHOLO_01467	2.46e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NBKGHOLO_01468	2.11e-82	-	-	-	-	-	-	-	-
NBKGHOLO_01469	1.39e-279	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
NBKGHOLO_01470	3.16e-187	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NBKGHOLO_01471	1.94e-100	usp5	-	-	T	-	-	-	universal stress protein
NBKGHOLO_01472	8.34e-86	-	-	-	K	-	-	-	Helix-turn-helix domain
NBKGHOLO_01473	3.45e-144	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NBKGHOLO_01474	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
NBKGHOLO_01475	1.57e-34	-	-	-	-	-	-	-	-
NBKGHOLO_01476	3e-113	-	-	-	-	-	-	-	-
NBKGHOLO_01477	1.18e-50	-	-	-	-	-	-	-	-
NBKGHOLO_01478	4.63e-230	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NBKGHOLO_01479	3.2e-301	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
NBKGHOLO_01480	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NBKGHOLO_01481	2.91e-232	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NBKGHOLO_01482	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NBKGHOLO_01483	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NBKGHOLO_01484	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NBKGHOLO_01485	1.74e-50	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NBKGHOLO_01486	5.78e-215	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NBKGHOLO_01487	8.37e-66	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NBKGHOLO_01488	4.96e-148	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
NBKGHOLO_01489	2.29e-48	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_01490	2.74e-231	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
NBKGHOLO_01491	6.36e-98	-	-	-	S	-	-	-	NusG domain II
NBKGHOLO_01492	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
NBKGHOLO_01493	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
NBKGHOLO_01494	1.99e-204	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NBKGHOLO_01495	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NBKGHOLO_01496	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NBKGHOLO_01497	1.76e-188	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
NBKGHOLO_01498	1.98e-148	-	-	-	I	-	-	-	ABC-2 family transporter protein
NBKGHOLO_01499	3.59e-206	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_01500	3.94e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NBKGHOLO_01501	3.56e-281	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NBKGHOLO_01502	1.04e-213	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_01503	3.88e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NBKGHOLO_01504	3.64e-223	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NBKGHOLO_01505	1.24e-205	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NBKGHOLO_01506	3.57e-262	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NBKGHOLO_01507	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NBKGHOLO_01508	1.8e-219	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NBKGHOLO_01509	1.02e-223	-	-	-	V	ko:K01421	-	ko00000	domain protein
NBKGHOLO_01510	9.9e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NBKGHOLO_01511	4.41e-155	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
NBKGHOLO_01512	1.2e-33	-	-	-	E	-	-	-	lactoylglutathione lyase activity
NBKGHOLO_01513	5.43e-276	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NBKGHOLO_01514	4.26e-226	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBKGHOLO_01515	2.34e-211	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NBKGHOLO_01516	2.72e-88	-	-	-	-	-	-	-	-
NBKGHOLO_01517	8.16e-285	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
NBKGHOLO_01518	3.71e-316	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NBKGHOLO_01519	4.79e-292	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NBKGHOLO_01520	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
NBKGHOLO_01521	3.25e-195	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NBKGHOLO_01522	9.92e-317	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
NBKGHOLO_01523	7.15e-94	usp1	-	-	T	-	-	-	Universal stress protein family
NBKGHOLO_01524	3.15e-173	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
NBKGHOLO_01525	1.46e-281	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
NBKGHOLO_01526	1.23e-190	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
NBKGHOLO_01527	2.36e-217	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
NBKGHOLO_01528	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NBKGHOLO_01529	4.9e-86	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
NBKGHOLO_01530	2.05e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NBKGHOLO_01531	1.77e-239	ydbI	-	-	K	-	-	-	AI-2E family transporter
NBKGHOLO_01532	1.68e-252	pbpX	-	-	V	-	-	-	Beta-lactamase
NBKGHOLO_01533	2.47e-195	-	-	-	S	-	-	-	zinc-ribbon domain
NBKGHOLO_01534	3.3e-39	-	-	-	-	-	-	-	-
NBKGHOLO_01535	1.15e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NBKGHOLO_01536	1.42e-49	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NBKGHOLO_01537	1.89e-220	-	-	-	U	-	-	-	Major Facilitator Superfamily
NBKGHOLO_01538	2.32e-109	-	-	-	F	-	-	-	NUDIX domain
NBKGHOLO_01539	1.86e-134	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NBKGHOLO_01540	3.81e-232	-	-	-	-	-	-	-	-
NBKGHOLO_01541	6.01e-210	-	-	-	S	-	-	-	Putative esterase
NBKGHOLO_01542	2.39e-13	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
NBKGHOLO_01543	3.31e-89	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
NBKGHOLO_01544	9.17e-37	-	-	-	-	-	-	-	-
NBKGHOLO_01545	4.07e-92	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
NBKGHOLO_01546	1.12e-213	nox	-	-	C	-	-	-	NADH oxidase
NBKGHOLO_01547	1.91e-67	-	-	-	T	-	-	-	diguanylate cyclase
NBKGHOLO_01548	4.08e-101	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NBKGHOLO_01549	1.61e-79	-	-	-	-	-	-	-	-
NBKGHOLO_01550	2.4e-98	-	-	-	S	-	-	-	Protein conserved in bacteria
NBKGHOLO_01551	7.82e-229	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
NBKGHOLO_01552	1.16e-104	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
NBKGHOLO_01553	3.21e-110	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
NBKGHOLO_01554	5.55e-101	-	-	-	T	-	-	-	diguanylate cyclase activity
NBKGHOLO_01555	6.46e-285	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
NBKGHOLO_01556	2.01e-243	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
NBKGHOLO_01557	7.93e-94	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
NBKGHOLO_01558	6.99e-99	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NBKGHOLO_01559	2.76e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NBKGHOLO_01560	5.61e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NBKGHOLO_01561	3.91e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
NBKGHOLO_01562	7.24e-211	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NBKGHOLO_01563	2.03e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NBKGHOLO_01564	4.91e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NBKGHOLO_01565	1.25e-87	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NBKGHOLO_01566	4.77e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NBKGHOLO_01567	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NBKGHOLO_01568	6.41e-196	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NBKGHOLO_01569	2.69e-181	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
NBKGHOLO_01570	1.54e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NBKGHOLO_01571	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NBKGHOLO_01572	6.28e-225	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NBKGHOLO_01573	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NBKGHOLO_01574	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NBKGHOLO_01575	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
NBKGHOLO_01576	5.8e-270	-	-	-	-	-	-	-	-
NBKGHOLO_01578	8.99e-37	-	-	-	S	-	-	-	MazG-like family
NBKGHOLO_01579	6.51e-213	-	-	-	S	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NBKGHOLO_01581	7.48e-46	-	-	-	-	-	-	-	-
NBKGHOLO_01582	9.72e-15	-	-	-	-	-	-	-	-
NBKGHOLO_01584	3.55e-155	-	-	-	-	-	-	-	-
NBKGHOLO_01586	0.0	-	-	-	G	-	-	-	Phosphodiester glycosidase
NBKGHOLO_01587	6.56e-184	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
NBKGHOLO_01588	7.99e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NBKGHOLO_01589	5.52e-139	-	-	-	-	-	-	-	-
NBKGHOLO_01590	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
NBKGHOLO_01591	9.69e-170	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
NBKGHOLO_01592	7.96e-169	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NBKGHOLO_01593	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NBKGHOLO_01595	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBKGHOLO_01596	1.85e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
NBKGHOLO_01597	1.26e-268	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
NBKGHOLO_01598	6.5e-71	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NBKGHOLO_01599	6.28e-130	-	-	-	-	-	-	-	-
NBKGHOLO_01600	9.83e-190	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
NBKGHOLO_01601	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
NBKGHOLO_01602	6.64e-171	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
NBKGHOLO_01603	1.67e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NBKGHOLO_01604	3.84e-264	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NBKGHOLO_01605	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NBKGHOLO_01606	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NBKGHOLO_01607	9.67e-200	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBKGHOLO_01608	2.95e-218	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBKGHOLO_01609	2.33e-240	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NBKGHOLO_01610	2.56e-223	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NBKGHOLO_01611	2.82e-147	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
NBKGHOLO_01612	3.39e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NBKGHOLO_01613	5.39e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
NBKGHOLO_01614	2.11e-159	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NBKGHOLO_01615	5.97e-106	ccl	-	-	S	-	-	-	QueT transporter
NBKGHOLO_01616	6.84e-167	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NBKGHOLO_01617	1.04e-163	epsB	-	-	M	-	-	-	biosynthesis protein
NBKGHOLO_01618	1.15e-142	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NBKGHOLO_01619	1.43e-250	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NBKGHOLO_01620	2.02e-93	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NBKGHOLO_01623	4.94e-83	-	2.7.8.12	-	S	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
NBKGHOLO_01624	2.88e-138	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
NBKGHOLO_01625	1.71e-32	-	-	-	M	-	-	-	group 2 family protein
NBKGHOLO_01626	5.88e-121	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	Polysaccharide biosynthesis protein
NBKGHOLO_01627	2.91e-22	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
NBKGHOLO_01628	1.39e-31	-	-	-	-	-	-	-	-
NBKGHOLO_01629	4.76e-100	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
NBKGHOLO_01630	5e-197	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NBKGHOLO_01631	2.22e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NBKGHOLO_01632	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
NBKGHOLO_01633	3.92e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
NBKGHOLO_01634	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
NBKGHOLO_01635	4.15e-183	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NBKGHOLO_01636	5.23e-173	-	-	-	M	-	-	-	Sortase family
NBKGHOLO_01637	1.19e-259	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NBKGHOLO_01638	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NBKGHOLO_01639	1.51e-254	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NBKGHOLO_01640	7.59e-268	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NBKGHOLO_01641	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
NBKGHOLO_01643	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NBKGHOLO_01644	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NBKGHOLO_01645	2.2e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NBKGHOLO_01646	3.38e-72	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NBKGHOLO_01647	6.36e-208	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NBKGHOLO_01648	2.28e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NBKGHOLO_01649	4.25e-203	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
NBKGHOLO_01650	7.86e-87	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_01651	8.86e-145	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
NBKGHOLO_01652	1.1e-13	-	-	-	-	-	-	-	-
NBKGHOLO_01653	1.93e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NBKGHOLO_01655	1.53e-218	-	-	-	-	-	-	-	-
NBKGHOLO_01656	8.66e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_01658	5.86e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NBKGHOLO_01659	1.18e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBKGHOLO_01660	2.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBKGHOLO_01661	4.63e-225	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
NBKGHOLO_01662	1.1e-145	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
NBKGHOLO_01663	9.36e-172	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
NBKGHOLO_01664	0.0	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
NBKGHOLO_01665	1.84e-109	-	-	-	-	-	-	-	-
NBKGHOLO_01666	7.75e-255	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NBKGHOLO_01667	8.66e-202	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
NBKGHOLO_01668	4.78e-144	-	-	-	M	-	-	-	Acyltransferase family
NBKGHOLO_01669	5.74e-224	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
NBKGHOLO_01670	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NBKGHOLO_01671	1.78e-276	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NBKGHOLO_01672	1.08e-150	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NBKGHOLO_01673	4.32e-251	-	-	-	M	-	-	-	Glycosyl transferases group 1
NBKGHOLO_01674	2.2e-314	-	-	-	S	-	-	-	polysaccharide biosynthetic process
NBKGHOLO_01675	7.17e-127	ywqC	-	-	M	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	capsule polysaccharide biosynthetic process
NBKGHOLO_01676	5.62e-108	-	-	-	D	-	-	-	Capsular exopolysaccharide family
NBKGHOLO_01677	6.9e-221	-	-	-	S	-	-	-	EpsG family
NBKGHOLO_01678	0.0	-	-	-	M	-	-	-	Sulfatase
NBKGHOLO_01679	4.41e-139	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
NBKGHOLO_01680	3.59e-301	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NBKGHOLO_01681	6.22e-210	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NBKGHOLO_01682	0.0	-	-	-	E	-	-	-	Amino Acid
NBKGHOLO_01683	3.26e-175	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_01684	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NBKGHOLO_01685	2.06e-219	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NBKGHOLO_01686	4.02e-165	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
NBKGHOLO_01687	1.51e-236	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NBKGHOLO_01688	1.86e-304	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NBKGHOLO_01689	1.29e-105	yjhE	-	-	S	-	-	-	Phage tail protein
NBKGHOLO_01690	3.27e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NBKGHOLO_01691	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NBKGHOLO_01692	1.82e-37	-	-	-	-	-	-	-	-
NBKGHOLO_01693	1.09e-23	-	-	-	-	-	-	-	-
NBKGHOLO_01694	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NBKGHOLO_01695	6.86e-108	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
NBKGHOLO_01696	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NBKGHOLO_01697	2.59e-55	-	-	-	-	-	-	-	-
NBKGHOLO_01698	4.51e-68	-	-	-	-	-	-	-	-
NBKGHOLO_01699	3.82e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NBKGHOLO_01700	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NBKGHOLO_01701	4.45e-93	-	-	-	S	-	-	-	KAP family P-loop domain
NBKGHOLO_01702	1.36e-13	-	-	-	L	-	-	-	Transposase domain (DUF772)
NBKGHOLO_01703	2.62e-67	-	-	-	-	-	-	-	-
NBKGHOLO_01704	3.07e-16	-	-	-	M	-	-	-	LysM domain
NBKGHOLO_01708	6.28e-33	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NBKGHOLO_01710	7.15e-44	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
NBKGHOLO_01711	2.82e-65	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
NBKGHOLO_01713	0.0	-	-	-	M	-	-	-	LysM domain
NBKGHOLO_01716	2.21e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
NBKGHOLO_01717	9.64e-152	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
NBKGHOLO_01718	2.61e-169	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
NBKGHOLO_01719	3.24e-89	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NBKGHOLO_01720	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
NBKGHOLO_01721	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NBKGHOLO_01722	2.72e-51	-	-	-	-	-	-	-	-
NBKGHOLO_01724	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NBKGHOLO_01725	5.52e-215	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NBKGHOLO_01726	1.42e-218	-	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NBKGHOLO_01727	4.29e-64	-	-	-	-	-	-	-	-
NBKGHOLO_01728	5.84e-252	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NBKGHOLO_01729	2.33e-206	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NBKGHOLO_01730	2.05e-112	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NBKGHOLO_01731	8.89e-192	-	-	-	-	-	-	-	-
NBKGHOLO_01733	1.28e-165	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NBKGHOLO_01734	5.73e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
NBKGHOLO_01735	5.51e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
NBKGHOLO_01736	1.12e-223	-	-	-	K	-	-	-	Helix-turn-helix domain
NBKGHOLO_01737	4.24e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NBKGHOLO_01738	8.17e-20	-	-	-	-	-	-	-	-
NBKGHOLO_01739	0.0	ypiB	-	-	EGP	-	-	-	Major Facilitator
NBKGHOLO_01740	4.19e-27	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NBKGHOLO_01742	6.93e-147	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
NBKGHOLO_01743	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
NBKGHOLO_01744	4.88e-208	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_01745	3.38e-172	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NBKGHOLO_01746	4.82e-83	ORF00048	-	-	-	-	-	-	-
NBKGHOLO_01747	2.89e-74	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
NBKGHOLO_01748	3.16e-136	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
NBKGHOLO_01749	1.3e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_01750	1.39e-130	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NBKGHOLO_01751	4.38e-56	-	-	-	-	-	-	-	-
NBKGHOLO_01752	1.43e-307	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
NBKGHOLO_01753	2.33e-68	-	-	-	-	-	-	-	-
NBKGHOLO_01754	7.15e-58	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
NBKGHOLO_01755	1.6e-250	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
NBKGHOLO_01756	4.63e-07	-	-	-	-	-	-	-	-
NBKGHOLO_01757	5.2e-229	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NBKGHOLO_01758	4.85e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
NBKGHOLO_01759	2.5e-199	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
NBKGHOLO_01760	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
NBKGHOLO_01761	5.65e-130	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NBKGHOLO_01762	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
NBKGHOLO_01763	6.87e-162	citR	-	-	K	-	-	-	FCD
NBKGHOLO_01764	6.12e-197	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NBKGHOLO_01766	4.44e-62	-	-	-	-	-	-	-	-
NBKGHOLO_01767	1.37e-90	-	-	-	-	-	-	-	-
NBKGHOLO_01768	6.71e-84	-	-	-	-	-	-	-	-
NBKGHOLO_01769	8.47e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NBKGHOLO_01770	2.53e-201	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NBKGHOLO_01771	1.49e-308	-	-	-	S	-	-	-	Fic/DOC family
NBKGHOLO_01772	2.89e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NBKGHOLO_01773	8.57e-134	-	-	-	-	-	-	-	-
NBKGHOLO_01774	3.88e-240	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
NBKGHOLO_01775	2.48e-13	-	-	-	-	-	-	-	-
NBKGHOLO_01776	1.14e-123	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NBKGHOLO_01777	1.96e-126	-	-	-	-	-	-	-	-
NBKGHOLO_01778	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NBKGHOLO_01779	1.97e-168	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NBKGHOLO_01781	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NBKGHOLO_01782	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NBKGHOLO_01783	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NBKGHOLO_01784	1.25e-283	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NBKGHOLO_01785	1.28e-65	-	-	-	-	-	-	-	-
NBKGHOLO_01786	1.01e-34	-	-	-	-	-	-	-	-
NBKGHOLO_01787	3.12e-115	-	-	-	S	-	-	-	MucBP domain
NBKGHOLO_01788	3.06e-151	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NBKGHOLO_01791	3.21e-115	-	-	-	E	-	-	-	AAA domain
NBKGHOLO_01792	8.96e-173	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NBKGHOLO_01793	2.5e-106	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
NBKGHOLO_01794	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NBKGHOLO_01795	3.18e-34	-	-	-	S	-	-	-	Virus attachment protein p12 family
NBKGHOLO_01796	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
NBKGHOLO_01797	3.89e-75	-	-	-	-	-	-	-	-
NBKGHOLO_01798	1.17e-295	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NBKGHOLO_01799	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
NBKGHOLO_01800	1.39e-96	-	-	-	S	-	-	-	function, without similarity to other proteins
NBKGHOLO_01801	2.43e-87	-	-	-	-	-	-	-	-
NBKGHOLO_01802	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_01803	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NBKGHOLO_01804	1.92e-200	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NBKGHOLO_01806	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NBKGHOLO_01807	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
NBKGHOLO_01808	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
NBKGHOLO_01809	7.93e-178	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NBKGHOLO_01810	2.49e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NBKGHOLO_01811	8.01e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NBKGHOLO_01812	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NBKGHOLO_01813	1.3e-284	-	-	-	V	-	-	-	Beta-lactamase
NBKGHOLO_01814	4.16e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NBKGHOLO_01815	1.01e-275	-	-	-	V	-	-	-	Beta-lactamase
NBKGHOLO_01816	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NBKGHOLO_01817	2.37e-95	-	-	-	-	-	-	-	-
NBKGHOLO_01818	1.8e-223	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_01819	1.77e-175	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NBKGHOLO_01820	7.57e-164	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_01821	7.51e-105	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NBKGHOLO_01822	1.57e-102	-	-	-	K	-	-	-	FR47-like protein
NBKGHOLO_01824	6.88e-129	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NBKGHOLO_01825	2.27e-269	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NBKGHOLO_01826	1.92e-200	-	-	-	G	-	-	-	Aldose 1-epimerase
NBKGHOLO_01827	1.49e-132	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
NBKGHOLO_01828	1.16e-205	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NBKGHOLO_01829	8.14e-63	-	-	-	-	-	-	-	-
NBKGHOLO_01830	1.47e-267	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NBKGHOLO_01831	1.47e-271	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NBKGHOLO_01832	3.04e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
NBKGHOLO_01834	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NBKGHOLO_01835	4.8e-104	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
NBKGHOLO_01836	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBKGHOLO_01837	2.24e-84	-	-	-	-	-	-	-	-
NBKGHOLO_01838	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NBKGHOLO_01839	1.67e-179	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NBKGHOLO_01840	6.05e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NBKGHOLO_01841	2.84e-125	-	-	-	-	-	-	-	-
NBKGHOLO_01842	1.96e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_01843	4.36e-264	yueF	-	-	S	-	-	-	AI-2E family transporter
NBKGHOLO_01844	1.13e-308	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
NBKGHOLO_01845	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NBKGHOLO_01846	2.87e-62	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
NBKGHOLO_01847	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NBKGHOLO_01848	9.5e-39	-	-	-	-	-	-	-	-
NBKGHOLO_01849	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NBKGHOLO_01850	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NBKGHOLO_01851	9.46e-15	-	-	-	-	-	-	-	-
NBKGHOLO_01852	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NBKGHOLO_01853	7.8e-135	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
NBKGHOLO_01854	3.48e-103	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NBKGHOLO_01855	2.47e-273	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NBKGHOLO_01856	1.9e-171	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NBKGHOLO_01857	5.52e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBKGHOLO_01858	2.06e-166	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBKGHOLO_01859	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBKGHOLO_01860	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NBKGHOLO_01861	5.3e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NBKGHOLO_01862	2.36e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NBKGHOLO_01863	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NBKGHOLO_01864	2.74e-285	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NBKGHOLO_01865	1.17e-101	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
NBKGHOLO_01866	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
NBKGHOLO_01867	3.12e-139	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NBKGHOLO_01868	1.37e-263	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
NBKGHOLO_01869	2.96e-156	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NBKGHOLO_01870	5.63e-178	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_01871	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
NBKGHOLO_01872	4.06e-118	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NBKGHOLO_01873	4.86e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NBKGHOLO_01874	1.8e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NBKGHOLO_01875	9.38e-158	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NBKGHOLO_01876	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
NBKGHOLO_01877	1.33e-225	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
NBKGHOLO_01878	2.26e-29	-	-	-	-	-	-	-	-
NBKGHOLO_01879	1.97e-88	-	-	-	-	-	-	-	-
NBKGHOLO_01881	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NBKGHOLO_01882	3.31e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NBKGHOLO_01883	5.47e-196	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NBKGHOLO_01884	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NBKGHOLO_01885	3.88e-73	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
NBKGHOLO_01886	1.25e-233	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
NBKGHOLO_01887	2.5e-203	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NBKGHOLO_01888	2.3e-76	-	-	-	S	-	-	-	YtxH-like protein
NBKGHOLO_01889	1.14e-96	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
NBKGHOLO_01890	6.63e-126	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_01891	3.79e-29	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_01892	1.47e-284	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_01893	3.05e-187	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
NBKGHOLO_01894	1.11e-154	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NBKGHOLO_01896	4.38e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
NBKGHOLO_01897	9.43e-146	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NBKGHOLO_01899	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NBKGHOLO_01900	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NBKGHOLO_01901	0.0	XK27_00195	-	-	K	-	-	-	Mga helix-turn-helix domain
NBKGHOLO_01902	0.0	-	-	-	N	-	-	-	domain, Protein
NBKGHOLO_01903	2.56e-177	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NBKGHOLO_01905	6.75e-245	-	-	-	S	-	-	-	Cell surface protein
NBKGHOLO_01907	4.05e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
NBKGHOLO_01908	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NBKGHOLO_01909	5.95e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NBKGHOLO_01910	6.65e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NBKGHOLO_01911	3.55e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NBKGHOLO_01912	1.58e-315	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
NBKGHOLO_01913	1.86e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NBKGHOLO_01914	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NBKGHOLO_01915	3.72e-77	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
NBKGHOLO_01916	1.68e-85	-	-	-	-	-	-	-	-
NBKGHOLO_01917	5.88e-163	-	-	-	S	-	-	-	SseB protein N-terminal domain
NBKGHOLO_01918	9.81e-175	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
NBKGHOLO_01919	7.48e-268	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
NBKGHOLO_01920	1.6e-93	-	-	-	K	-	-	-	Transcriptional regulator
NBKGHOLO_01921	2.6e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NBKGHOLO_01922	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NBKGHOLO_01923	1.44e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NBKGHOLO_01924	4.79e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NBKGHOLO_01925	1.68e-228	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
NBKGHOLO_01926	8.79e-156	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
NBKGHOLO_01927	3.89e-243	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NBKGHOLO_01928	7.32e-216	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NBKGHOLO_01929	6.15e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
NBKGHOLO_01930	4.62e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NBKGHOLO_01931	3.25e-64	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NBKGHOLO_01932	1.19e-150	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NBKGHOLO_01933	3.75e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NBKGHOLO_01934	1.68e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NBKGHOLO_01935	9.8e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
NBKGHOLO_01936	6.96e-263	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NBKGHOLO_01937	3.4e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NBKGHOLO_01938	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NBKGHOLO_01939	1.01e-157	csrR	-	-	K	-	-	-	response regulator
NBKGHOLO_01940	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NBKGHOLO_01941	5.42e-229	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NBKGHOLO_01942	1.45e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NBKGHOLO_01943	8.64e-176	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBKGHOLO_01944	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NBKGHOLO_01945	1.44e-88	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NBKGHOLO_01946	2.5e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NBKGHOLO_01947	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NBKGHOLO_01948	3.35e-268	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NBKGHOLO_01949	3.43e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NBKGHOLO_01950	6.1e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NBKGHOLO_01951	3.99e-167	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
NBKGHOLO_01952	2.79e-234	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NBKGHOLO_01953	3.39e-148	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
NBKGHOLO_01954	1.91e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NBKGHOLO_01955	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
NBKGHOLO_01956	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NBKGHOLO_01957	1.05e-155	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
NBKGHOLO_01958	1.37e-54	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NBKGHOLO_01959	2.91e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NBKGHOLO_01960	6.47e-95	yqhL	-	-	P	-	-	-	Rhodanese-like protein
NBKGHOLO_01961	2.75e-34	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NBKGHOLO_01962	4.85e-231	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NBKGHOLO_01963	3.34e-305	ynbB	-	-	P	-	-	-	aluminum resistance
NBKGHOLO_01964	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
NBKGHOLO_01965	5.4e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
NBKGHOLO_01966	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NBKGHOLO_01967	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NBKGHOLO_01968	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
NBKGHOLO_01970	9.01e-296	-	-	-	S	-	-	-	Membrane
NBKGHOLO_01971	1.77e-20	-	-	-	-	-	-	-	-
NBKGHOLO_01972	6.33e-42	-	-	-	-	-	-	-	-
NBKGHOLO_01973	1.18e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NBKGHOLO_01974	4.18e-73	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
NBKGHOLO_01975	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NBKGHOLO_01976	1.76e-258	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NBKGHOLO_01977	4.27e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NBKGHOLO_01978	8.72e-100	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NBKGHOLO_01979	1.29e-87	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NBKGHOLO_01980	9.8e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NBKGHOLO_01981	1.1e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NBKGHOLO_01982	2.87e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NBKGHOLO_01983	3.6e-183	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NBKGHOLO_01984	4.68e-196	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NBKGHOLO_01985	3.59e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NBKGHOLO_01986	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NBKGHOLO_01987	3.29e-67	-	-	-	-	-	-	-	-
NBKGHOLO_01988	7.71e-157	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
NBKGHOLO_01989	5.09e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NBKGHOLO_01990	4.4e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NBKGHOLO_01991	6.86e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NBKGHOLO_01992	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NBKGHOLO_01993	1.68e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NBKGHOLO_01994	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NBKGHOLO_01995	3.02e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NBKGHOLO_01996	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NBKGHOLO_01997	1.36e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NBKGHOLO_01998	2.81e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NBKGHOLO_01999	1.4e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NBKGHOLO_02000	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NBKGHOLO_02001	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NBKGHOLO_02002	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NBKGHOLO_02003	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NBKGHOLO_02004	1.72e-242	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NBKGHOLO_02005	9.22e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NBKGHOLO_02006	1.85e-241	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NBKGHOLO_02007	1.33e-227	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NBKGHOLO_02008	2.35e-218	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBKGHOLO_02009	8.85e-194	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NBKGHOLO_02010	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NBKGHOLO_02011	2.68e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NBKGHOLO_02012	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NBKGHOLO_02013	7.76e-234	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NBKGHOLO_02014	1.12e-69	-	-	-	-	-	-	-	-
NBKGHOLO_02015	1.47e-33	-	-	-	-	-	-	-	-
NBKGHOLO_02016	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NBKGHOLO_02017	1.02e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NBKGHOLO_02018	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NBKGHOLO_02019	2.2e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NBKGHOLO_02020	1.52e-120	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NBKGHOLO_02021	7.48e-190	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NBKGHOLO_02022	1.16e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NBKGHOLO_02023	1.08e-35	-	-	-	-	-	-	-	-
NBKGHOLO_02024	3.45e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
NBKGHOLO_02025	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
NBKGHOLO_02026	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_02027	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_02028	2.2e-177	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
NBKGHOLO_02029	2.43e-302	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NBKGHOLO_02030	5.71e-158	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NBKGHOLO_02031	1.01e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
NBKGHOLO_02032	1.06e-62	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
NBKGHOLO_02033	2.79e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NBKGHOLO_02034	3.28e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NBKGHOLO_02035	9.72e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NBKGHOLO_02036	4.96e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NBKGHOLO_02037	3.69e-180	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NBKGHOLO_02038	2.79e-181	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NBKGHOLO_02039	2.89e-291	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NBKGHOLO_02040	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NBKGHOLO_02041	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NBKGHOLO_02042	3.81e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NBKGHOLO_02043	1.75e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NBKGHOLO_02044	2.02e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NBKGHOLO_02045	7.54e-59	ylxQ	-	-	J	-	-	-	ribosomal protein
NBKGHOLO_02046	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NBKGHOLO_02047	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NBKGHOLO_02048	4.46e-181	yceF	-	-	P	ko:K05794	-	ko00000	membrane
NBKGHOLO_02049	2.52e-208	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NBKGHOLO_02050	1.28e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NBKGHOLO_02051	4.89e-285	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NBKGHOLO_02052	2.27e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NBKGHOLO_02053	4.87e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NBKGHOLO_02054	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NBKGHOLO_02055	6.01e-268	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NBKGHOLO_02056	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NBKGHOLO_02057	4.01e-44	-	-	-	-	-	-	-	-
NBKGHOLO_02058	1.33e-105	-	-	-	S	-	-	-	ASCH
NBKGHOLO_02059	2.01e-81	-	-	-	-	-	-	-	-
NBKGHOLO_02060	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NBKGHOLO_02061	4.87e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NBKGHOLO_02062	5.14e-116	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NBKGHOLO_02063	8.85e-72	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
NBKGHOLO_02064	1.23e-185	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
NBKGHOLO_02065	2.52e-237	-	-	-	-	-	-	-	-
NBKGHOLO_02066	1.17e-285	-	-	-	-	-	-	-	-
NBKGHOLO_02067	0.0	-	-	-	-	-	-	-	-
NBKGHOLO_02069	0.0	-	2.4.1.9, 3.4.24.40	GH68	M	ko:K01406,ko:K20811	ko00500,ko01503,map00500,map01503	ko00000,ko00001,ko01000,ko01002	domain protein
NBKGHOLO_02071	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NBKGHOLO_02072	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NBKGHOLO_02073	4.34e-237	mocA	-	-	S	-	-	-	Oxidoreductase
NBKGHOLO_02074	2.64e-116	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NBKGHOLO_02075	6.26e-143	-	-	-	S	-	-	-	Flavodoxin-like fold
NBKGHOLO_02077	2.8e-79	-	-	-	-	-	-	-	-
NBKGHOLO_02078	3.45e-37	-	-	-	-	-	-	-	-
NBKGHOLO_02079	3.69e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NBKGHOLO_02080	1.1e-50	-	-	-	-	-	-	-	-
NBKGHOLO_02081	2.63e-142	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NBKGHOLO_02082	1.22e-113	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
NBKGHOLO_02083	1.27e-219	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NBKGHOLO_02084	1.37e-162	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NBKGHOLO_02085	1.7e-70	-	-	-	-	-	-	-	-
NBKGHOLO_02086	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBKGHOLO_02087	7.58e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NBKGHOLO_02088	1.78e-148	-	-	-	J	-	-	-	HAD-hyrolase-like
NBKGHOLO_02089	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
NBKGHOLO_02090	2.55e-105	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
NBKGHOLO_02091	9.81e-201	-	-	-	V	-	-	-	ABC transporter
NBKGHOLO_02092	0.0	-	-	-	-	-	-	-	-
NBKGHOLO_02094	1.79e-302	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NBKGHOLO_02095	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NBKGHOLO_02096	4.4e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NBKGHOLO_02097	1.04e-214	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NBKGHOLO_02098	1.41e-211	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NBKGHOLO_02099	4.18e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NBKGHOLO_02100	5.66e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NBKGHOLO_02101	1.47e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NBKGHOLO_02102	4.64e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NBKGHOLO_02103	1.03e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NBKGHOLO_02104	4.25e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NBKGHOLO_02105	3.4e-83	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NBKGHOLO_02106	2.36e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NBKGHOLO_02107	6.29e-191	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NBKGHOLO_02108	3.11e-71	-	-	-	-	-	-	-	-
NBKGHOLO_02109	5.66e-14	-	-	-	-	-	-	-	-
NBKGHOLO_02111	1.96e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NBKGHOLO_02112	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NBKGHOLO_02113	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NBKGHOLO_02114	1.21e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NBKGHOLO_02115	1.49e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NBKGHOLO_02116	4.3e-186	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NBKGHOLO_02117	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NBKGHOLO_02118	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	(ABC) transporter
NBKGHOLO_02119	1.05e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NBKGHOLO_02120	9.47e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NBKGHOLO_02121	5.06e-181	-	-	-	-	-	-	-	-
NBKGHOLO_02122	8.92e-222	-	-	-	-	-	-	-	-
NBKGHOLO_02123	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NBKGHOLO_02125	1.78e-241	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NBKGHOLO_02126	1.28e-229	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NBKGHOLO_02127	1.2e-211	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NBKGHOLO_02128	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NBKGHOLO_02129	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NBKGHOLO_02130	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NBKGHOLO_02131	8.92e-111	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NBKGHOLO_02132	4e-280	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NBKGHOLO_02133	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NBKGHOLO_02134	2.83e-144	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
NBKGHOLO_02135	8.05e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NBKGHOLO_02136	7.79e-112	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NBKGHOLO_02137	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NBKGHOLO_02138	6.99e-155	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NBKGHOLO_02139	1.87e-137	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NBKGHOLO_02140	5.37e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NBKGHOLO_02142	1.44e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NBKGHOLO_02143	1.73e-220	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NBKGHOLO_02144	7.29e-46	-	-	-	-	-	-	-	-
NBKGHOLO_02145	4.08e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NBKGHOLO_02146	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NBKGHOLO_02147	2.53e-210	lysR	-	-	K	-	-	-	Transcriptional regulator
NBKGHOLO_02149	2.95e-240	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBKGHOLO_02150	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBKGHOLO_02151	1.76e-51	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NBKGHOLO_02152	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NBKGHOLO_02153	4.86e-05	-	-	-	-	-	-	-	-
NBKGHOLO_02154	5.46e-72	-	-	-	-	-	-	-	-
NBKGHOLO_02155	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBKGHOLO_02156	1.72e-142	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NBKGHOLO_02157	5.59e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
NBKGHOLO_02158	5.76e-84	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
NBKGHOLO_02159	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NBKGHOLO_02160	1.99e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NBKGHOLO_02161	1.74e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NBKGHOLO_02162	3.67e-126	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NBKGHOLO_02163	2.33e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NBKGHOLO_02164	5.88e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NBKGHOLO_02165	2.76e-306	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NBKGHOLO_02166	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NBKGHOLO_02167	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NBKGHOLO_02168	9.32e-194	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NBKGHOLO_02169	1.55e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NBKGHOLO_02170	3.69e-143	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NBKGHOLO_02171	3.31e-246	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NBKGHOLO_02172	1.43e-67	-	-	-	S	-	-	-	MazG-like family
NBKGHOLO_02173	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NBKGHOLO_02175	3.08e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
NBKGHOLO_02176	3.8e-130	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
NBKGHOLO_02177	1.99e-260	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
NBKGHOLO_02178	1.1e-277	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NBKGHOLO_02179	1.34e-139	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NBKGHOLO_02180	3.62e-287	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NBKGHOLO_02181	8.43e-12	-	-	-	-	-	-	-	-
NBKGHOLO_02182	8.19e-134	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
NBKGHOLO_02183	1.15e-144	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NBKGHOLO_02184	1.38e-170	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NBKGHOLO_02185	4.26e-171	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NBKGHOLO_02186	4.81e-76	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NBKGHOLO_02187	5.01e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
NBKGHOLO_02188	4.53e-263	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NBKGHOLO_02189	3.82e-187	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
NBKGHOLO_02190	1.76e-145	-	-	-	C	-	-	-	Nitroreductase family
NBKGHOLO_02191	1.22e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_02192	7.37e-90	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_02193	2.13e-277	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
NBKGHOLO_02194	1.24e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NBKGHOLO_02195	5.58e-221	-	-	-	T	-	-	-	Histidine kinase-like ATPases
NBKGHOLO_02196	5.18e-174	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_02197	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
NBKGHOLO_02198	1.93e-265	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NBKGHOLO_02199	3.94e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NBKGHOLO_02200	1.15e-235	-	-	-	K	-	-	-	LysR substrate binding domain
NBKGHOLO_02201	3.64e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NBKGHOLO_02202	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NBKGHOLO_02203	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NBKGHOLO_02204	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NBKGHOLO_02205	5.92e-142	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NBKGHOLO_02206	4.61e-220	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NBKGHOLO_02207	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NBKGHOLO_02208	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NBKGHOLO_02209	3.34e-214	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
NBKGHOLO_02210	3.4e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NBKGHOLO_02211	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NBKGHOLO_02212	4.65e-189	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NBKGHOLO_02213	1.61e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NBKGHOLO_02214	7.5e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NBKGHOLO_02215	3.82e-166	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
NBKGHOLO_02216	8.49e-12	-	-	-	-	-	-	-	-
NBKGHOLO_02217	4.97e-62	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NBKGHOLO_02219	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NBKGHOLO_02220	2.52e-55	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NBKGHOLO_02221	1.41e-125	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NBKGHOLO_02222	5.89e-145	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
NBKGHOLO_02223	3.87e-202	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NBKGHOLO_02224	2.79e-190	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
NBKGHOLO_02225	9.09e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NBKGHOLO_02226	1.48e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NBKGHOLO_02227	1.03e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NBKGHOLO_02228	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_02229	2.08e-110	-	-	-	-	-	-	-	-
NBKGHOLO_02230	1.12e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NBKGHOLO_02231	2.95e-207	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NBKGHOLO_02232	3.7e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NBKGHOLO_02233	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NBKGHOLO_02234	3.67e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NBKGHOLO_02235	6.19e-300	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NBKGHOLO_02236	1.09e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NBKGHOLO_02237	6.23e-87	-	-	-	M	-	-	-	Lysin motif
NBKGHOLO_02238	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NBKGHOLO_02239	1.83e-231	-	-	-	S	-	-	-	Helix-turn-helix domain
NBKGHOLO_02240	4.03e-61	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
NBKGHOLO_02241	4.54e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NBKGHOLO_02242	3.03e-178	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NBKGHOLO_02243	6.34e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NBKGHOLO_02244	8.93e-163	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NBKGHOLO_02245	2.81e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NBKGHOLO_02246	2.09e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
NBKGHOLO_02247	7.26e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NBKGHOLO_02248	7.15e-94	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
NBKGHOLO_02249	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NBKGHOLO_02250	9e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NBKGHOLO_02251	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NBKGHOLO_02252	2.92e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NBKGHOLO_02253	2.15e-187	-	-	-	-	-	-	-	-
NBKGHOLO_02254	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
NBKGHOLO_02255	3.37e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NBKGHOLO_02256	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NBKGHOLO_02257	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NBKGHOLO_02258	5.47e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
NBKGHOLO_02259	1.28e-181	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
NBKGHOLO_02260	2.92e-232	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NBKGHOLO_02261	0.0	oatA	-	-	I	-	-	-	Acyltransferase
NBKGHOLO_02262	1.29e-297	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NBKGHOLO_02263	5.84e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
NBKGHOLO_02264	4.92e-212	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NBKGHOLO_02265	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
NBKGHOLO_02266	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NBKGHOLO_02267	1.33e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_02268	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NBKGHOLO_02269	2.34e-28	-	-	-	-	-	-	-	-
NBKGHOLO_02270	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
NBKGHOLO_02271	5.12e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NBKGHOLO_02272	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NBKGHOLO_02273	8.34e-271	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NBKGHOLO_02274	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
NBKGHOLO_02275	2.93e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NBKGHOLO_02276	1.12e-83	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NBKGHOLO_02277	1.24e-172	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
NBKGHOLO_02278	1.14e-108	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
NBKGHOLO_02279	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NBKGHOLO_02280	1.98e-205	-	-	-	S	-	-	-	Tetratricopeptide repeat
NBKGHOLO_02281	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NBKGHOLO_02282	6.79e-152	-	-	-	-	-	-	-	-
NBKGHOLO_02283	2.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NBKGHOLO_02284	1.01e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NBKGHOLO_02285	7.05e-248	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NBKGHOLO_02286	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NBKGHOLO_02287	1.96e-147	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
NBKGHOLO_02288	2.04e-247	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NBKGHOLO_02289	2.96e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NBKGHOLO_02290	2.89e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NBKGHOLO_02291	2.84e-75	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
NBKGHOLO_02292	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NBKGHOLO_02293	3.76e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NBKGHOLO_02294	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NBKGHOLO_02295	1.06e-186	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NBKGHOLO_02296	8.74e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NBKGHOLO_02297	7.16e-201	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
NBKGHOLO_02298	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NBKGHOLO_02299	6.23e-314	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NBKGHOLO_02300	1.34e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
NBKGHOLO_02301	1.65e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NBKGHOLO_02302	8.12e-174	-	-	-	S	-	-	-	E1-E2 ATPase
NBKGHOLO_02303	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NBKGHOLO_02304	1.83e-35	-	-	-	-	-	-	-	-
NBKGHOLO_02305	2.95e-96	-	-	-	-	-	-	-	-
NBKGHOLO_02307	4.07e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NBKGHOLO_02308	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NBKGHOLO_02309	2.93e-235	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NBKGHOLO_02310	2.35e-311	-	-	-	S	-	-	-	Sterol carrier protein domain
NBKGHOLO_02311	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NBKGHOLO_02312	8.3e-150	-	-	-	S	-	-	-	repeat protein
NBKGHOLO_02313	9.46e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
NBKGHOLO_02314	6.89e-289	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NBKGHOLO_02315	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
NBKGHOLO_02316	3.61e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NBKGHOLO_02317	9.79e-279	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NBKGHOLO_02318	3.94e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NBKGHOLO_02319	1.36e-46	-	-	-	-	-	-	-	-
NBKGHOLO_02320	1.56e-127	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NBKGHOLO_02321	9.37e-150	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NBKGHOLO_02322	2.44e-267	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
NBKGHOLO_02323	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
NBKGHOLO_02324	6.09e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NBKGHOLO_02325	2.98e-49	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NBKGHOLO_02326	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NBKGHOLO_02327	2.93e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
NBKGHOLO_02328	1.91e-185	ylmH	-	-	S	-	-	-	S4 domain protein
NBKGHOLO_02329	6.86e-60	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
NBKGHOLO_02330	5.1e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NBKGHOLO_02331	2.19e-290	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NBKGHOLO_02332	6.05e-307	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NBKGHOLO_02333	4.67e-196	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NBKGHOLO_02334	3.84e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NBKGHOLO_02335	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NBKGHOLO_02336	3.67e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NBKGHOLO_02337	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NBKGHOLO_02338	8.26e-80	ftsL	-	-	D	-	-	-	cell division protein FtsL
NBKGHOLO_02339	4.57e-217	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NBKGHOLO_02340	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NBKGHOLO_02341	4.32e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NBKGHOLO_02342	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBKGHOLO_02344	1.63e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NBKGHOLO_02345	1.29e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
NBKGHOLO_02346	2.77e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NBKGHOLO_02347	6.07e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
NBKGHOLO_02348	1.28e-146	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NBKGHOLO_02349	2.13e-113	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NBKGHOLO_02350	5.62e-193	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NBKGHOLO_02351	6.84e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NBKGHOLO_02352	2.01e-151	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NBKGHOLO_02353	1.63e-147	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NBKGHOLO_02354	5.13e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NBKGHOLO_02355	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NBKGHOLO_02356	3.97e-149	-	-	-	K	ko:K01926	-	ko00000,ko03000	CoA binding domain
NBKGHOLO_02357	1.73e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NBKGHOLO_02358	3.81e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NBKGHOLO_02359	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NBKGHOLO_02360	6.83e-109	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NBKGHOLO_02361	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NBKGHOLO_02363	0.0	-	-	-	KL	-	-	-	Helicase conserved C-terminal domain
NBKGHOLO_02364	5.76e-139	-	-	-	S	-	-	-	Domain of unknown function (DUF1998)
NBKGHOLO_02365	2.14e-164	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
NBKGHOLO_02366	1.13e-289	-	-	-	E	-	-	-	Amino acid permease
NBKGHOLO_02367	2.4e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NBKGHOLO_02368	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
NBKGHOLO_02369	3.68e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_02370	4.64e-188	-	-	-	-	-	-	-	-
NBKGHOLO_02371	0.0	-	-	-	-	-	-	-	-
NBKGHOLO_02372	1.83e-202	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_02373	6.21e-165	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NBKGHOLO_02374	1.62e-256	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NBKGHOLO_02375	2.93e-133	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
NBKGHOLO_02376	1.04e-135	-	-	-	-	-	-	-	-
NBKGHOLO_02377	8.05e-197	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
NBKGHOLO_02378	4.66e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_02379	1.72e-208	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_02380	1.14e-107	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NBKGHOLO_02381	5.9e-15	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NBKGHOLO_02382	4.39e-06	-	-	-	-	-	-	-	-
NBKGHOLO_02383	2.24e-72	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NBKGHOLO_02384	1.63e-103	yphH	-	-	S	-	-	-	Cupin domain
NBKGHOLO_02385	1.2e-207	-	-	-	K	-	-	-	Transcriptional regulator
NBKGHOLO_02386	8.81e-166	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NBKGHOLO_02387	3.75e-214	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NBKGHOLO_02388	1.38e-153	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NBKGHOLO_02389	1.15e-204	-	-	-	T	-	-	-	GHKL domain
NBKGHOLO_02390	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NBKGHOLO_02391	9.53e-202	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
NBKGHOLO_02392	3.98e-171	-	-	-	F	-	-	-	deoxynucleoside kinase
NBKGHOLO_02393	1.02e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NBKGHOLO_02394	5.95e-212	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
NBKGHOLO_02395	1.4e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NBKGHOLO_02396	2.9e-158	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NBKGHOLO_02397	1.01e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NBKGHOLO_02398	2.93e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
NBKGHOLO_02399	4.72e-141	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
NBKGHOLO_02400	1.63e-95	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NBKGHOLO_02401	0.0	-	6.3.2.2	-	M	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain protein
NBKGHOLO_02402	1.84e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NBKGHOLO_02403	1.41e-53	-	-	-	-	-	-	-	-
NBKGHOLO_02404	6.47e-110	uspA	-	-	T	-	-	-	universal stress protein
NBKGHOLO_02405	2.16e-206	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBKGHOLO_02406	3.54e-230	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
NBKGHOLO_02407	8.1e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NBKGHOLO_02408	2.14e-36	-	-	-	-	-	-	-	-
NBKGHOLO_02410	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NBKGHOLO_02411	1.42e-102	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NBKGHOLO_02412	1.39e-281	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NBKGHOLO_02413	1.21e-243	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NBKGHOLO_02414	2.4e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NBKGHOLO_02415	5.58e-151	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBKGHOLO_02416	9.88e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NBKGHOLO_02417	8.69e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NBKGHOLO_02418	1.56e-189	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NBKGHOLO_02419	2.56e-272	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NBKGHOLO_02420	1.41e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
NBKGHOLO_02421	1.35e-283	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NBKGHOLO_02422	2.92e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NBKGHOLO_02423	1.62e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NBKGHOLO_02424	5.48e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
NBKGHOLO_02425	6.1e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NBKGHOLO_02426	2.5e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NBKGHOLO_02427	5.78e-19	-	-	-	-	-	-	-	-
NBKGHOLO_02428	6.51e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NBKGHOLO_02429	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NBKGHOLO_02431	1.78e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NBKGHOLO_02432	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NBKGHOLO_02433	4.59e-115	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NBKGHOLO_02434	8.51e-72	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NBKGHOLO_02435	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NBKGHOLO_02436	4.11e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NBKGHOLO_02437	8.75e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NBKGHOLO_02438	1.29e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NBKGHOLO_02439	7.03e-246	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NBKGHOLO_02440	1.63e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NBKGHOLO_02441	1.47e-250	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NBKGHOLO_02442	1.36e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NBKGHOLO_02443	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
NBKGHOLO_02444	2.09e-244	ampC	-	-	V	-	-	-	Beta-lactamase
NBKGHOLO_02445	6.47e-209	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
NBKGHOLO_02446	2.49e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NBKGHOLO_02447	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NBKGHOLO_02448	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_02449	5.26e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NBKGHOLO_02450	1.19e-166	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
NBKGHOLO_02452	1.24e-31	-	-	-	-	-	-	-	-
NBKGHOLO_02456	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NBKGHOLO_02457	8e-247	yttB	-	-	EGP	-	-	-	Major Facilitator
NBKGHOLO_02458	1.56e-25	-	-	-	-	-	-	-	-
NBKGHOLO_02466	4e-110	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
NBKGHOLO_02467	3.12e-220	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
NBKGHOLO_02468	6.51e-293	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
NBKGHOLO_02469	7.92e-102	-	-	-	S	-	-	-	Pfam Transposase IS66
NBKGHOLO_02470	7.26e-183	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NBKGHOLO_02471	7.12e-62	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NBKGHOLO_02473	6.55e-277	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NBKGHOLO_02474	7.21e-87	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NBKGHOLO_02476	6.78e-82	-	-	-	-	-	-	-	-
NBKGHOLO_02477	2.92e-06	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
NBKGHOLO_02478	3.36e-256	-	-	-	S	-	-	-	peptidoglycan catabolic process
NBKGHOLO_02479	1.91e-73	-	-	-	S	-	-	-	Phage tail protein
NBKGHOLO_02480	1e-66	-	-	-	D	-	-	-	Phage tail tape measure protein, TP901 family
NBKGHOLO_02483	4.38e-110	-	-	-	S	-	-	-	Phage major tail protein 2
NBKGHOLO_02485	4.89e-22	-	-	-	S	-	-	-	exonuclease activity
NBKGHOLO_02487	7.23e-38	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NBKGHOLO_02488	4.34e-184	-	-	-	-	-	-	-	-
NBKGHOLO_02489	3.2e-137	-	-	-	-	-	-	-	-
NBKGHOLO_02490	6.61e-42	-	-	-	S	-	-	-	aminoacyl-tRNA ligase activity
NBKGHOLO_02491	4.89e-79	-	-	-	S	-	-	-	Phage Mu protein F like protein
NBKGHOLO_02492	6.18e-223	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
NBKGHOLO_02493	1.49e-221	-	-	-	S	-	-	-	Phage terminase large subunit
NBKGHOLO_02494	1.3e-98	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
NBKGHOLO_02495	4.65e-67	-	-	-	-	-	-	-	-
NBKGHOLO_02496	9.03e-68	-	-	-	L	-	-	-	NUMOD4 motif
NBKGHOLO_02497	5.68e-280	-	-	-	S	-	-	-	GcrA cell cycle regulator
NBKGHOLO_02498	7.09e-29	-	-	-	-	-	-	-	-
NBKGHOLO_02499	1.48e-99	-	-	-	-	-	-	-	-
NBKGHOLO_02501	1.13e-34	-	-	-	S	-	-	-	YopX protein
NBKGHOLO_02503	2.22e-34	-	-	-	-	-	-	-	-
NBKGHOLO_02505	8.5e-70	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
NBKGHOLO_02506	3.96e-45	-	-	-	-	-	-	-	-
NBKGHOLO_02509	6.19e-161	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
NBKGHOLO_02510	1.37e-152	-	-	-	L	-	-	-	Replication initiation and membrane attachment
NBKGHOLO_02511	5.82e-169	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
NBKGHOLO_02512	1.1e-197	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
NBKGHOLO_02515	1.03e-22	-	-	-	-	-	-	-	-
NBKGHOLO_02517	4.46e-127	-	-	-	-	-	-	-	-
NBKGHOLO_02519	2.98e-19	-	-	-	S	ko:K09946	-	ko00000	Domain of unknown function (DUF1508)
NBKGHOLO_02521	2.1e-45	-	-	-	K	-	-	-	Helix-turn-helix domain
NBKGHOLO_02522	1.42e-71	-	-	-	K	-	-	-	Helix-turn-helix domain
NBKGHOLO_02523	1.91e-98	-	-	-	E	-	-	-	Zn peptidase
NBKGHOLO_02524	9.78e-51	-	-	-	-	-	-	-	-
NBKGHOLO_02525	1.28e-50	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NBKGHOLO_02526	1.04e-288	-	-	-	L	-	-	-	Pfam:Integrase_AP2
NBKGHOLO_02527	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NBKGHOLO_02528	5.43e-195	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NBKGHOLO_02529	3.74e-142	vanZ	-	-	V	-	-	-	VanZ like family
NBKGHOLO_02530	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NBKGHOLO_02531	1.37e-165	-	-	-	-	-	-	-	-
NBKGHOLO_02532	1.8e-134	-	-	-	-	-	-	-	-
NBKGHOLO_02534	1.74e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NBKGHOLO_02535	2.43e-263	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NBKGHOLO_02536	1.87e-304	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NBKGHOLO_02537	7.6e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NBKGHOLO_02538	1.84e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NBKGHOLO_02539	2.8e-105	yvbK	-	-	K	-	-	-	GNAT family
NBKGHOLO_02540	1.73e-35	-	-	-	T	-	-	-	PFAM SpoVT AbrB
NBKGHOLO_02541	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NBKGHOLO_02542	2.84e-215	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
NBKGHOLO_02543	5.01e-142	-	-	-	-	-	-	-	-
NBKGHOLO_02544	4.96e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NBKGHOLO_02545	3.76e-107	-	-	-	S	-	-	-	Fic/DOC family
NBKGHOLO_02546	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NBKGHOLO_02547	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
NBKGHOLO_02548	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NBKGHOLO_02549	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NBKGHOLO_02550	1.09e-270	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NBKGHOLO_02551	1.06e-39	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NBKGHOLO_02552	2.08e-58	-	-	-	M	-	-	-	Glycosyl transferase family 8
NBKGHOLO_02553	1.89e-150	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
NBKGHOLO_02554	1.53e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NBKGHOLO_02555	6.33e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NBKGHOLO_02556	2.12e-40	-	-	-	-	-	-	-	-
NBKGHOLO_02558	9.28e-248	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NBKGHOLO_02559	9.54e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NBKGHOLO_02560	3.71e-105	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NBKGHOLO_02561	1.82e-229	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NBKGHOLO_02562	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
NBKGHOLO_02563	6.23e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBKGHOLO_02565	3.32e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NBKGHOLO_02566	1.35e-304	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
NBKGHOLO_02567	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NBKGHOLO_02568	5.65e-07	-	-	-	-	-	-	-	-
NBKGHOLO_02570	1.1e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
NBKGHOLO_02571	2.05e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NBKGHOLO_02572	1.46e-300	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NBKGHOLO_02573	1.14e-228	mocA	-	-	S	-	-	-	Oxidoreductase
NBKGHOLO_02574	3.98e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
NBKGHOLO_02575	3.83e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NBKGHOLO_02576	1.28e-171	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NBKGHOLO_02577	1.99e-12	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBKGHOLO_02578	1.05e-40	-	-	-	-	-	-	-	-
NBKGHOLO_02579	1.95e-166	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
NBKGHOLO_02580	7.88e-211	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
NBKGHOLO_02581	7.53e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBKGHOLO_02582	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NBKGHOLO_02583	2.97e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
NBKGHOLO_02584	8.93e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NBKGHOLO_02585	8.36e-277	yttB	-	-	EGP	-	-	-	Major Facilitator
NBKGHOLO_02586	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBKGHOLO_02587	2.02e-247	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NBKGHOLO_02588	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NBKGHOLO_02589	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NBKGHOLO_02590	1.26e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NBKGHOLO_02591	2.36e-260	camS	-	-	S	-	-	-	sex pheromone
NBKGHOLO_02592	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NBKGHOLO_02593	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NBKGHOLO_02594	1.3e-51	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
NBKGHOLO_02595	2.4e-163	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
NBKGHOLO_02596	2.46e-255	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
NBKGHOLO_02598	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
NBKGHOLO_02599	1.41e-77	-	-	-	-	-	-	-	-
NBKGHOLO_02600	2.24e-106	-	-	-	-	-	-	-	-
NBKGHOLO_02601	1.49e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
NBKGHOLO_02602	2.21e-42	-	-	-	-	-	-	-	-
NBKGHOLO_02603	1.9e-121	-	-	-	S	-	-	-	acetyltransferase
NBKGHOLO_02604	0.0	yclK	-	-	T	-	-	-	Histidine kinase
NBKGHOLO_02605	3.15e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NBKGHOLO_02606	1.55e-91	-	-	-	S	-	-	-	SdpI/YhfL protein family
NBKGHOLO_02608	1.26e-52	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NBKGHOLO_02609	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
NBKGHOLO_02610	2.3e-23	-	-	-	-	-	-	-	-
NBKGHOLO_02611	1.37e-17	-	-	-	S	-	-	-	Phage head-tail joining protein
NBKGHOLO_02612	4.43e-61	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NBKGHOLO_02613	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
NBKGHOLO_02614	1.39e-277	-	-	-	S	-	-	-	Phage portal protein
NBKGHOLO_02615	1.04e-29	-	-	-	-	-	-	-	-
NBKGHOLO_02616	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
NBKGHOLO_02617	9.4e-105	terS	-	-	L	-	-	-	Phage terminase, small subunit
NBKGHOLO_02620	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
NBKGHOLO_02621	2.31e-69	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
NBKGHOLO_02622	4.64e-118	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
NBKGHOLO_02624	1.38e-20	-	-	-	-	-	-	-	-
NBKGHOLO_02625	3.27e-79	-	-	-	-	-	-	-	-
NBKGHOLO_02626	7.55e-58	-	-	-	-	-	-	-	-
NBKGHOLO_02627	2.32e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
NBKGHOLO_02628	2.48e-274	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NBKGHOLO_02629	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NBKGHOLO_02630	2.93e-207	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
NBKGHOLO_02631	6.11e-229	arbY	-	-	M	-	-	-	family 8
NBKGHOLO_02632	1.36e-210	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
NBKGHOLO_02633	1.34e-184	arbV	-	-	I	-	-	-	Phosphate acyltransferases
NBKGHOLO_02634	1.03e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NBKGHOLO_02635	1.58e-96	-	-	-	-	-	-	-	-
NBKGHOLO_02636	3.7e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NBKGHOLO_02637	7.52e-65	-	-	-	-	-	-	-	-
NBKGHOLO_02638	2.14e-105	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
NBKGHOLO_02639	3.45e-63	-	-	-	-	-	-	-	-
NBKGHOLO_02641	2e-64	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
NBKGHOLO_02642	1.91e-211	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
NBKGHOLO_02643	5.7e-183	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NBKGHOLO_02644	1.75e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NBKGHOLO_02645	1.8e-119	-	-	-	S	-	-	-	VanZ like family
NBKGHOLO_02646	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
NBKGHOLO_02647	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NBKGHOLO_02648	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NBKGHOLO_02649	2.39e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
NBKGHOLO_02650	2.69e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NBKGHOLO_02651	1.12e-162	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NBKGHOLO_02652	1.19e-104	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_02653	1.97e-75	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_02654	7.67e-152	-	-	-	K	-	-	-	Transcriptional regulator
NBKGHOLO_02655	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
NBKGHOLO_02657	2.37e-79	-	-	-	-	-	-	-	-
NBKGHOLO_02658	3.85e-116	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NBKGHOLO_02659	4.03e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBKGHOLO_02660	7.08e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBKGHOLO_02661	2.13e-191	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBKGHOLO_02662	9.49e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NBKGHOLO_02663	4.84e-125	-	-	-	K	-	-	-	Cupin domain
NBKGHOLO_02664	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NBKGHOLO_02665	2.74e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NBKGHOLO_02666	3.32e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NBKGHOLO_02667	1.62e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NBKGHOLO_02668	2.05e-278	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NBKGHOLO_02669	2.96e-210	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBKGHOLO_02670	1.2e-106	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NBKGHOLO_02671	6.35e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NBKGHOLO_02672	4.68e-168	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NBKGHOLO_02673	4.87e-204	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NBKGHOLO_02674	5.33e-119	-	-	-	-	-	-	-	-
NBKGHOLO_02675	7.94e-134	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
NBKGHOLO_02676	2.11e-249	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NBKGHOLO_02677	1.21e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
NBKGHOLO_02678	1.1e-188	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NBKGHOLO_02679	5.23e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NBKGHOLO_02680	6.97e-304	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
NBKGHOLO_02682	7.78e-66	-	-	-	-	-	-	-	-
NBKGHOLO_02683	3.38e-149	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NBKGHOLO_02684	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NBKGHOLO_02685	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NBKGHOLO_02686	9.03e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NBKGHOLO_02687	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NBKGHOLO_02688	3.69e-177	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
NBKGHOLO_02689	2.92e-42	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NBKGHOLO_02690	1.48e-78	-	-	-	-	-	-	-	-
NBKGHOLO_02691	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NBKGHOLO_02692	5.53e-84	-	-	-	-	-	-	-	-
NBKGHOLO_02693	5.04e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NBKGHOLO_02694	8.05e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NBKGHOLO_02695	1.52e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NBKGHOLO_02696	2.99e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NBKGHOLO_02697	2.73e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
NBKGHOLO_02699	1.71e-131	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NBKGHOLO_02700	6.45e-105	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
NBKGHOLO_02701	3.36e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NBKGHOLO_02702	8.22e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NBKGHOLO_02703	1.47e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NBKGHOLO_02704	2.98e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NBKGHOLO_02705	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NBKGHOLO_02706	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NBKGHOLO_02707	2.32e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
NBKGHOLO_02708	2.3e-178	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NBKGHOLO_02709	4.45e-105	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NBKGHOLO_02710	1.21e-117	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NBKGHOLO_02711	3.28e-143	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NBKGHOLO_02712	2.18e-109	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NBKGHOLO_02713	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NBKGHOLO_02714	8.36e-230	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NBKGHOLO_02715	1.8e-249	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NBKGHOLO_02716	2e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NBKGHOLO_02717	5.82e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NBKGHOLO_02718	2.28e-61	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NBKGHOLO_02719	7.01e-49	-	-	-	-	-	-	-	-
NBKGHOLO_02720	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
NBKGHOLO_02721	1.33e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NBKGHOLO_02722	1.75e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NBKGHOLO_02723	1.83e-191	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NBKGHOLO_02724	3.55e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NBKGHOLO_02725	1.56e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NBKGHOLO_02726	5.25e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NBKGHOLO_02727	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NBKGHOLO_02728	9.79e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NBKGHOLO_02729	4.6e-250	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NBKGHOLO_02730	4.17e-204	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NBKGHOLO_02731	2.59e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
NBKGHOLO_02732	6.43e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NBKGHOLO_02733	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NBKGHOLO_02734	7.96e-127	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NBKGHOLO_02735	1.8e-117	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NBKGHOLO_02736	3.04e-297	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NBKGHOLO_02737	1.57e-151	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NBKGHOLO_02738	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NBKGHOLO_02739	2.37e-29	-	-	-	-	-	-	-	-
NBKGHOLO_02740	1.28e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBKGHOLO_02741	6.68e-240	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NBKGHOLO_02742	3.23e-288	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NBKGHOLO_02743	7.88e-135	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NBKGHOLO_02744	1.8e-167	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
NBKGHOLO_02745	1.43e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NBKGHOLO_02746	3.94e-309	ymfH	-	-	S	-	-	-	Peptidase M16
NBKGHOLO_02747	8.63e-292	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NBKGHOLO_02748	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NBKGHOLO_02749	1.26e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
NBKGHOLO_02750	6.48e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NBKGHOLO_02751	9.45e-198	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
NBKGHOLO_02752	9.63e-220	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NBKGHOLO_02753	9.97e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NBKGHOLO_02754	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NBKGHOLO_02755	7.55e-82	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NBKGHOLO_02756	3.13e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NBKGHOLO_02757	1.61e-185	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NBKGHOLO_02758	1.51e-144	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
NBKGHOLO_02759	3.99e-258	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NBKGHOLO_02760	5.18e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NBKGHOLO_02761	2.24e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NBKGHOLO_02762	4.15e-160	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NBKGHOLO_02763	8.17e-135	-	-	-	S	-	-	-	CYTH
NBKGHOLO_02764	8.12e-151	yjbH	-	-	Q	-	-	-	Thioredoxin
NBKGHOLO_02765	1.17e-270	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NBKGHOLO_02766	3.14e-310	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NBKGHOLO_02767	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NBKGHOLO_02768	5.43e-281	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NBKGHOLO_02769	1.49e-287	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NBKGHOLO_02770	3.41e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
NBKGHOLO_02772	9.29e-123	-	-	-	F	-	-	-	NUDIX domain
NBKGHOLO_02773	7.2e-81	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NBKGHOLO_02774	8.6e-65	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NBKGHOLO_02775	8.09e-48	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NBKGHOLO_02776	6.61e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NBKGHOLO_02777	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NBKGHOLO_02778	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NBKGHOLO_02779	2.47e-154	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
NBKGHOLO_02780	1.25e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NBKGHOLO_02781	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NBKGHOLO_02782	3.41e-107	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NBKGHOLO_02783	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
NBKGHOLO_02784	1.66e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NBKGHOLO_02785	1e-138	-	-	-	-	-	-	-	-
NBKGHOLO_02787	1.21e-11	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
NBKGHOLO_02789	6.86e-287	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NBKGHOLO_02790	6.64e-80	hol	-	-	S	-	-	-	Bacteriophage holin
NBKGHOLO_02791	4.74e-70	-	-	-	-	-	-	-	-
NBKGHOLO_02793	6.88e-71	-	-	-	-	-	-	-	-
NBKGHOLO_02794	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
NBKGHOLO_02795	4.37e-295	-	-	-	S	-	-	-	Phage tail protein
NBKGHOLO_02796	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
NBKGHOLO_02797	2.72e-27	-	-	-	-	-	-	-	-
NBKGHOLO_02798	2.06e-94	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
NBKGHOLO_02799	9.29e-39	-	-	-	-	-	-	-	-
NBKGHOLO_02800	9.41e-87	-	-	-	S	-	-	-	exonuclease activity
NBKGHOLO_02801	9.69e-53	-	-	-	S	-	-	-	Phage head-tail joining protein
NBKGHOLO_02802	4.38e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NBKGHOLO_02803	4.67e-37	-	-	-	S	-	-	-	peptidase activity
NBKGHOLO_02804	4.01e-262	-	-	-	S	-	-	-	peptidase activity
NBKGHOLO_02805	3.83e-139	-	-	-	S	-	-	-	peptidase activity
NBKGHOLO_02806	1.26e-287	-	-	-	S	-	-	-	Phage portal protein
NBKGHOLO_02808	0.0	-	-	-	S	-	-	-	Phage Terminase
NBKGHOLO_02809	2.83e-99	-	-	-	S	-	-	-	Phage terminase, small subunit
NBKGHOLO_02810	1.23e-90	-	-	-	L	-	-	-	HNH nucleases
NBKGHOLO_02812	1.04e-66	-	-	-	-	-	-	-	-
NBKGHOLO_02813	4.04e-58	-	-	-	C	-	-	-	Domain of unknown function (DUF4145)
NBKGHOLO_02814	9.74e-98	-	-	-	-	-	-	-	-
NBKGHOLO_02817	8.35e-27	-	-	-	S	-	-	-	YopX protein
NBKGHOLO_02818	1.78e-48	-	-	-	-	-	-	-	-
NBKGHOLO_02820	5.53e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
NBKGHOLO_02822	2.2e-160	-	-	-	S	-	-	-	DNA methylation
NBKGHOLO_02823	9.79e-132	-	-	-	S	-	-	-	C-5 cytosine-specific DNA methylase
NBKGHOLO_02824	2.27e-86	-	-	-	S	-	-	-	magnesium ion binding
NBKGHOLO_02825	4.44e-51	-	-	-	-	-	-	-	-
NBKGHOLO_02828	9.41e-296	-	-	-	S	-	-	-	DNA helicase activity
NBKGHOLO_02829	2.03e-147	-	-	-	S	-	-	-	calcium ion binding
NBKGHOLO_02830	5.12e-73	-	-	-	S	-	-	-	Single-strand binding protein family
NBKGHOLO_02831	5.42e-155	-	-	-	S	-	-	-	Pfam:HNHc_6
NBKGHOLO_02832	3.66e-53	-	-	-	S	-	-	-	ERF superfamily
NBKGHOLO_02833	8.85e-102	-	-	-	S	-	-	-	Siphovirus Gp157
NBKGHOLO_02839	1.84e-163	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
NBKGHOLO_02841	4.86e-77	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBKGHOLO_02842	4.13e-23	-	-	-	E	-	-	-	Zn peptidase
NBKGHOLO_02843	4.04e-13	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
NBKGHOLO_02844	1.91e-24	-	-	-	S	-	-	-	Short C-terminal domain
NBKGHOLO_02849	5.57e-270	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NBKGHOLO_02852	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
NBKGHOLO_02853	0.0	-	-	-	L	-	-	-	Transposase DDE domain
NBKGHOLO_02854	1.45e-46	-	-	-	-	-	-	-	-
NBKGHOLO_02855	8.79e-106	-	-	-	L	-	-	-	COG4584 Transposase and inactivated derivatives
NBKGHOLO_02859	1.75e-31	-	-	-	K	-	-	-	TetR Family
NBKGHOLO_02860	6.4e-98	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NBKGHOLO_02861	7.92e-84	-	-	-	K	-	-	-	Transcriptional regulator