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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HNMDAKOP_00001	0.0	-	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	EcoEI R protein C-terminal
HNMDAKOP_00003	1.67e-165	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HNMDAKOP_00006	3.45e-70	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HNMDAKOP_00007	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HNMDAKOP_00008	7.47e-76	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HNMDAKOP_00009	4.7e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNMDAKOP_00010	2.25e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HNMDAKOP_00011	5.61e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HNMDAKOP_00012	3.92e-188	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HNMDAKOP_00013	3.74e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HNMDAKOP_00014	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HNMDAKOP_00015	1.41e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HNMDAKOP_00016	3e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNMDAKOP_00017	1.45e-197	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HNMDAKOP_00018	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNMDAKOP_00019	2.09e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HNMDAKOP_00020	1.22e-218	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HNMDAKOP_00021	1.9e-115	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HNMDAKOP_00022	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HNMDAKOP_00023	2.79e-227	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HNMDAKOP_00024	4.22e-121	-	-	-	K	-	-	-	LysR substrate binding domain
HNMDAKOP_00025	8.27e-130	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HNMDAKOP_00027	3.54e-94	-	-	-	-	-	-	-	-
HNMDAKOP_00028	8.21e-226	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HNMDAKOP_00029	1.58e-104	-	-	-	K	-	-	-	Transcriptional regulator
HNMDAKOP_00030	5.95e-106	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HNMDAKOP_00031	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HNMDAKOP_00032	3.83e-89	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HNMDAKOP_00033	1.42e-61	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HNMDAKOP_00034	1.7e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HNMDAKOP_00035	1.49e-93	-	-	-	K	-	-	-	LytTr DNA-binding domain
HNMDAKOP_00036	1.24e-147	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HNMDAKOP_00037	3.29e-140	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HNMDAKOP_00038	1.26e-95	-	-	-	S	-	-	-	reductase
HNMDAKOP_00039	9.91e-137	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HNMDAKOP_00040	3.45e-150	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HNMDAKOP_00041	6.87e-162	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HNMDAKOP_00042	5.16e-306	-	-	-	T	-	-	-	GHKL domain
HNMDAKOP_00043	1.23e-113	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HNMDAKOP_00044	2.76e-188	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HNMDAKOP_00045	6.14e-116	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HNMDAKOP_00046	3.23e-315	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HNMDAKOP_00047	1.1e-234	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HNMDAKOP_00048	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HNMDAKOP_00049	2.11e-315	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HNMDAKOP_00050	8.41e-108	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HNMDAKOP_00051	7.42e-244	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HNMDAKOP_00052	1.38e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HNMDAKOP_00053	2.39e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HNMDAKOP_00054	4.3e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HNMDAKOP_00055	7.1e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HNMDAKOP_00056	2.05e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HNMDAKOP_00057	2.01e-285	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HNMDAKOP_00058	2.79e-293	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HNMDAKOP_00059	1.4e-104	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HNMDAKOP_00060	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HNMDAKOP_00061	5.08e-72	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HNMDAKOP_00062	1.26e-52	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HNMDAKOP_00063	8.83e-18	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HNMDAKOP_00064	1.32e-198	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HNMDAKOP_00065	5.88e-175	-	-	-	H	-	-	-	Nodulation protein S (NodS)
HNMDAKOP_00066	4.34e-22	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HNMDAKOP_00067	5.26e-107	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HNMDAKOP_00068	3.64e-07	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HNMDAKOP_00070	1.43e-172	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HNMDAKOP_00071	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HNMDAKOP_00072	7.16e-224	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HNMDAKOP_00074	7.76e-50	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HNMDAKOP_00075	2.11e-193	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HNMDAKOP_00076	4.62e-192	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HNMDAKOP_00077	8.04e-221	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HNMDAKOP_00078	9.69e-275	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HNMDAKOP_00079	1.42e-219	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HNMDAKOP_00080	2.6e-21	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HNMDAKOP_00081	5.52e-122	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMDAKOP_00082	1.89e-36	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HNMDAKOP_00083	2.67e-41	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HNMDAKOP_00084	7.05e-113	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HNMDAKOP_00085	2.89e-97	-	-	-	S	-	-	-	Cupin domain
HNMDAKOP_00086	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HNMDAKOP_00087	2.18e-91	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HNMDAKOP_00088	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HNMDAKOP_00089	9.11e-197	-	-	-	C	-	-	-	Aldo keto reductase
HNMDAKOP_00090	1.7e-74	lysR	-	-	K	-	-	-	Transcriptional regulator
HNMDAKOP_00091	1.25e-297	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HNMDAKOP_00093	5.19e-18	-	-	-	GM	-	-	-	NmrA-like family
HNMDAKOP_00094	6.94e-94	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HNMDAKOP_00095	2.05e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
HNMDAKOP_00096	3.59e-261	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HNMDAKOP_00097	0.0	-	-	-	LV	-	-	-	Eco57I restriction-modification methylase
HNMDAKOP_00098	6.41e-80	-	-	-	LO	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HNMDAKOP_00099	1.11e-07	-	-	-	S	-	-	-	Protein of unknown function (DUF3644)
HNMDAKOP_00100	1.63e-29	-	-	-	S	-	-	-	Protein of unknown function (DUF3644)
HNMDAKOP_00101	0.0	-	-	-	S	-	-	-	PglZ domain
HNMDAKOP_00102	3.26e-07	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HNMDAKOP_00103	3e-78	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HNMDAKOP_00104	1.52e-33	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HNMDAKOP_00105	1.12e-172	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HNMDAKOP_00106	1.61e-290	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HNMDAKOP_00107	7.72e-197	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HNMDAKOP_00108	6.98e-100	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HNMDAKOP_00109	6.47e-149	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HNMDAKOP_00110	3.82e-148	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HNMDAKOP_00111	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNMDAKOP_00112	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNMDAKOP_00113	6.35e-31	-	-	-	K	-	-	-	Transcriptional regulator
HNMDAKOP_00114	2.13e-54	-	-	-	K	-	-	-	Transcriptional regulator
HNMDAKOP_00115	4.97e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HNMDAKOP_00116	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HNMDAKOP_00117	9.62e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNMDAKOP_00118	1.05e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HNMDAKOP_00119	7.75e-258	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HNMDAKOP_00120	1.11e-207	lysR	-	-	K	-	-	-	Transcriptional regulator
HNMDAKOP_00121	1.12e-195	-	-	-	-	-	-	-	-
HNMDAKOP_00122	1.85e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
HNMDAKOP_00123	1.32e-84	-	-	-	-	-	-	-	-
HNMDAKOP_00124	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HNMDAKOP_00125	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HNMDAKOP_00126	2.35e-245	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HNMDAKOP_00127	1.13e-217	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HNMDAKOP_00128	7.17e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HNMDAKOP_00129	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HNMDAKOP_00130	8.84e-74	-	-	-	-	-	-	-	-
HNMDAKOP_00131	3.29e-111	degV1	-	-	S	-	-	-	DegV family
HNMDAKOP_00132	1.6e-271	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HNMDAKOP_00133	7.55e-306	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HNMDAKOP_00134	7.05e-270	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HNMDAKOP_00135	5.36e-92	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HNMDAKOP_00136	4.98e-131	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HNMDAKOP_00137	5.29e-148	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HNMDAKOP_00138	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HNMDAKOP_00139	1.3e-146	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HNMDAKOP_00140	4.67e-147	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HNMDAKOP_00141	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HNMDAKOP_00142	1.48e-114	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HNMDAKOP_00143	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HNMDAKOP_00144	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HNMDAKOP_00145	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HNMDAKOP_00146	1.07e-211	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HNMDAKOP_00147	1.53e-219	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HNMDAKOP_00148	2.4e-257	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HNMDAKOP_00149	5.27e-237	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HNMDAKOP_00150	3.24e-249	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HNMDAKOP_00151	8.25e-181	-	-	-	G	-	-	-	Transmembrane secretion effector
HNMDAKOP_00152	2.73e-59	-	-	-	G	-	-	-	Transmembrane secretion effector
HNMDAKOP_00153	2.32e-190	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HNMDAKOP_00154	2.84e-207	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HNMDAKOP_00155	2.78e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HNMDAKOP_00156	3.01e-191	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HNMDAKOP_00157	5.62e-106	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HNMDAKOP_00158	1.08e-102	-	-	-	S	-	-	-	ASCH
HNMDAKOP_00159	7.99e-180	-	-	-	F	-	-	-	Phosphorylase superfamily
HNMDAKOP_00160	1.09e-72	-	-	-	F	-	-	-	Phosphorylase superfamily
HNMDAKOP_00161	1.19e-23	-	-	-	F	-	-	-	Phosphorylase superfamily
HNMDAKOP_00162	5.92e-107	-	-	-	F	-	-	-	NUDIX domain
HNMDAKOP_00163	4.78e-183	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HNMDAKOP_00164	2.45e-97	-	-	-	S	-	-	-	AAA domain
HNMDAKOP_00165	1.11e-161	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
HNMDAKOP_00166	1.67e-23	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HNMDAKOP_00167	2.86e-108	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
HNMDAKOP_00168	1.19e-113	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HNMDAKOP_00169	1.21e-45	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HNMDAKOP_00170	5.31e-57	-	-	-	-	-	-	-	-
HNMDAKOP_00171	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HNMDAKOP_00172	8.78e-226	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
HNMDAKOP_00173	1.11e-184	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HNMDAKOP_00174	1.21e-47	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HNMDAKOP_00175	6.66e-244	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HNMDAKOP_00176	4.82e-37	-	-	-	S	-	-	-	SnoaL-like domain
HNMDAKOP_00177	1.2e-93	-	-	-	C	-	-	-	nitroreductase
HNMDAKOP_00178	3.65e-14	-	-	-	C	-	-	-	nitroreductase
HNMDAKOP_00179	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HNMDAKOP_00180	1.77e-29	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HNMDAKOP_00181	1.47e-49	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HNMDAKOP_00183	2.95e-77	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HNMDAKOP_00184	1.12e-110	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HNMDAKOP_00185	3.41e-194	-	-	-	M	-	-	-	Glycosyl transferases group 1
HNMDAKOP_00186	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HNMDAKOP_00187	9.4e-138	pncA	-	-	Q	-	-	-	Isochorismatase family
HNMDAKOP_00188	9.37e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNMDAKOP_00189	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HNMDAKOP_00190	8.13e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HNMDAKOP_00191	3.57e-298	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HNMDAKOP_00192	7.44e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HNMDAKOP_00193	2.14e-119	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNMDAKOP_00194	2.16e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HNMDAKOP_00195	2.39e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HNMDAKOP_00196	3.57e-150	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HNMDAKOP_00197	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HNMDAKOP_00198	1.23e-188	yxeH	-	-	S	-	-	-	hydrolase
HNMDAKOP_00199	2e-223	-	-	-	S	-	-	-	DUF218 domain
HNMDAKOP_00200	1.62e-09	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HNMDAKOP_00201	1.39e-47	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HNMDAKOP_00202	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HNMDAKOP_00203	1.47e-219	-	-	-	-	-	-	-	-
HNMDAKOP_00204	1.22e-165	-	-	-	-	-	-	-	-
HNMDAKOP_00205	6.78e-130	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HNMDAKOP_00206	5.06e-31	-	-	-	-	-	-	-	-
HNMDAKOP_00207	1.39e-173	-	-	-	-	-	-	-	-
HNMDAKOP_00208	1.23e-184	-	-	-	-	-	-	-	-
HNMDAKOP_00209	1.17e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HNMDAKOP_00210	2.45e-77	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HNMDAKOP_00211	5.16e-311	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HNMDAKOP_00212	2.61e-192	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HNMDAKOP_00213	7.05e-158	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HNMDAKOP_00214	4.24e-187	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HNMDAKOP_00215	4.45e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_00216	8.29e-151	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HNMDAKOP_00217	9.72e-147	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HNMDAKOP_00218	4.99e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HNMDAKOP_00219	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HNMDAKOP_00220	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HNMDAKOP_00221	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HNMDAKOP_00222	4.44e-172	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HNMDAKOP_00223	3.48e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNMDAKOP_00224	1.39e-113	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HNMDAKOP_00225	1.17e-220	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HNMDAKOP_00226	5.18e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HNMDAKOP_00227	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HNMDAKOP_00228	5.7e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HNMDAKOP_00229	8.49e-66	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HNMDAKOP_00230	1.01e-194	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HNMDAKOP_00231	1.06e-155	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HNMDAKOP_00232	3.17e-202	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNMDAKOP_00233	8.63e-131	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HNMDAKOP_00234	1.95e-172	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HNMDAKOP_00235	4.46e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HNMDAKOP_00236	1.24e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HNMDAKOP_00237	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HNMDAKOP_00238	8.64e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HNMDAKOP_00239	4.59e-93	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HNMDAKOP_00240	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNMDAKOP_00241	3.71e-83	-	-	-	-	-	-	-	-
HNMDAKOP_00242	2.76e-219	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HNMDAKOP_00243	2.84e-109	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HNMDAKOP_00244	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HNMDAKOP_00245	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HNMDAKOP_00246	1.1e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HNMDAKOP_00247	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HNMDAKOP_00248	8.52e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HNMDAKOP_00249	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HNMDAKOP_00250	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HNMDAKOP_00251	1.36e-114	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HNMDAKOP_00252	4.86e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HNMDAKOP_00253	2.6e-197	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HNMDAKOP_00254	7.05e-89	-	-	-	L	-	-	-	nuclease
HNMDAKOP_00255	3.6e-183	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HNMDAKOP_00256	2.33e-63	-	-	-	K	-	-	-	Helix-turn-helix domain
HNMDAKOP_00257	2.72e-236	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HNMDAKOP_00258	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HNMDAKOP_00260	3.52e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNMDAKOP_00261	8.86e-133	-	-	-	I	-	-	-	PAP2 superfamily
HNMDAKOP_00262	8.25e-218	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
HNMDAKOP_00263	1.72e-75	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HNMDAKOP_00264	4.4e-18	-	-	-	-	-	-	-	-
HNMDAKOP_00267	4.49e-273	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HNMDAKOP_00268	8.64e-84	-	-	-	-	-	-	-	-
HNMDAKOP_00269	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
HNMDAKOP_00270	3.66e-185	-	-	-	S	-	-	-	phage tail
HNMDAKOP_00271	0.0	-	-	-	D	-	-	-	SLT domain
HNMDAKOP_00274	1.37e-129	-	-	-	S	-	-	-	Phage tail tube protein
HNMDAKOP_00276	4.24e-59	-	-	-	S	-	-	-	exonuclease activity
HNMDAKOP_00278	4.73e-85	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HNMDAKOP_00279	8.59e-221	-	-	-	-	-	-	-	-
HNMDAKOP_00280	3.31e-116	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HNMDAKOP_00282	4.41e-218	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
HNMDAKOP_00283	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HNMDAKOP_00284	1.31e-303	yqaT	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
HNMDAKOP_00285	9.49e-98	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HNMDAKOP_00286	3.7e-155	-	-	-	-	-	-	-	-
HNMDAKOP_00287	6.16e-121	-	-	-	S	-	-	-	Super-infection exclusion protein B
HNMDAKOP_00291	6.31e-88	-	-	-	S	-	-	-	Endodeoxyribonuclease RusA
HNMDAKOP_00295	2.93e-75	-	-	-	S	-	-	-	IstB-like ATP binding protein
HNMDAKOP_00296	4.83e-45	-	-	-	K	-	-	-	Conserved phage C-terminus (Phg_2220_C)
HNMDAKOP_00297	1.76e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
HNMDAKOP_00298	3.8e-43	-	-	-	S	-	-	-	Siphovirus Gp157
HNMDAKOP_00299	3.97e-32	-	-	-	-	-	-	-	-
HNMDAKOP_00300	1.04e-27	-	-	-	-	-	-	-	-
HNMDAKOP_00301	1.09e-42	-	-	-	-	-	-	-	-
HNMDAKOP_00303	4.22e-41	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HNMDAKOP_00306	2.6e-38	-	-	-	-	-	-	-	-
HNMDAKOP_00307	8.66e-127	-	-	-	K	-	-	-	ORF6N domain
HNMDAKOP_00308	2.24e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HNMDAKOP_00309	1.08e-29	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HNMDAKOP_00310	3.74e-59	-	-	-	E	-	-	-	Zn peptidase
HNMDAKOP_00311	4.13e-83	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HNMDAKOP_00312	5.48e-27	-	-	-	-	-	-	-	-
HNMDAKOP_00313	1.04e-140	-	-	-	-	-	-	-	-
HNMDAKOP_00314	5.09e-283	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HNMDAKOP_00315	1.81e-274	-	-	-	S	-	-	-	Sterol carrier protein domain
HNMDAKOP_00316	4.35e-56	-	-	-	I	-	-	-	Acyltransferase
HNMDAKOP_00317	2.99e-118	-	-	-	I	-	-	-	Acyltransferase
HNMDAKOP_00318	1.02e-146	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HNMDAKOP_00319	4.27e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HNMDAKOP_00320	1.07e-176	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HNMDAKOP_00321	2.4e-195	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HNMDAKOP_00322	1.07e-23	-	-	-	-	-	-	-	-
HNMDAKOP_00323	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HNMDAKOP_00324	2.77e-307	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HNMDAKOP_00325	4.17e-100	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HNMDAKOP_00326	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HNMDAKOP_00327	5.87e-196	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HNMDAKOP_00328	5.18e-263	XK27_02480	-	-	EGP	-	-	-	Major facilitator Superfamily
HNMDAKOP_00329	1.5e-20	-	-	-	S	-	-	-	CsbD-like
HNMDAKOP_00330	1.83e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
HNMDAKOP_00331	6.22e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HNMDAKOP_00332	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HNMDAKOP_00333	7.89e-177	-	-	-	S	-	-	-	Alpha beta hydrolase
HNMDAKOP_00334	4.32e-37	-	-	-	-	-	-	-	-
HNMDAKOP_00335	4.17e-222	ydbI	-	-	K	-	-	-	AI-2E family transporter
HNMDAKOP_00336	4.68e-315	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HNMDAKOP_00337	7e-266	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HNMDAKOP_00338	7.9e-130	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HNMDAKOP_00339	1.59e-245	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNMDAKOP_00340	0.0	-	-	-	S	-	-	-	domain, Protein
HNMDAKOP_00341	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HNMDAKOP_00342	2.18e-217	-	-	-	K	-	-	-	LysR substrate binding domain
HNMDAKOP_00343	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HNMDAKOP_00344	1.17e-304	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HNMDAKOP_00345	9.54e-170	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HNMDAKOP_00346	1.62e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HNMDAKOP_00347	8.07e-233	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HNMDAKOP_00348	1.01e-308	-	-	-	P	-	-	-	Major Facilitator Superfamily
HNMDAKOP_00349	1.41e-112	-	-	-	P	-	-	-	Major Facilitator Superfamily
HNMDAKOP_00350	1.7e-53	-	-	-	P	-	-	-	Major Facilitator Superfamily
HNMDAKOP_00351	1.78e-106	-	-	-	P	-	-	-	Major Facilitator Superfamily
HNMDAKOP_00352	1.66e-210	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HNMDAKOP_00353	2.24e-239	-	-	-	M	-	-	-	Glycosyl transferase family 8
HNMDAKOP_00354	8.41e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
HNMDAKOP_00355	2.52e-199	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HNMDAKOP_00356	3.43e-189	-	-	-	I	-	-	-	Acyl-transferase
HNMDAKOP_00358	9.55e-76	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HNMDAKOP_00359	2.31e-44	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HNMDAKOP_00360	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HNMDAKOP_00361	1.49e-315	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HNMDAKOP_00362	5.77e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNMDAKOP_00363	6.44e-240	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HNMDAKOP_00364	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNMDAKOP_00365	0.0	potE	-	-	E	-	-	-	Amino Acid
HNMDAKOP_00366	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HNMDAKOP_00367	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HNMDAKOP_00368	7.7e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HNMDAKOP_00369	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HNMDAKOP_00370	3.33e-250	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HNMDAKOP_00371	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HNMDAKOP_00372	4.58e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HNMDAKOP_00373	3.61e-245	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HNMDAKOP_00374	7.87e-29	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HNMDAKOP_00375	4.4e-39	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HNMDAKOP_00376	5.47e-142	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HNMDAKOP_00377	4.92e-77	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HNMDAKOP_00378	6.95e-76	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HNMDAKOP_00379	2.24e-118	-	-	-	K	-	-	-	acetyltransferase
HNMDAKOP_00381	9.92e-207	yvgN	-	-	C	-	-	-	Aldo keto reductase
HNMDAKOP_00382	1.14e-310	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HNMDAKOP_00383	1.05e-71	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
HNMDAKOP_00384	7.28e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HNMDAKOP_00385	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HNMDAKOP_00386	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
HNMDAKOP_00387	0.0	-	-	-	S	-	-	-	TerB-C domain
HNMDAKOP_00388	7.01e-131	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HNMDAKOP_00389	1.01e-87	-	-	-	-	-	-	-	-
HNMDAKOP_00390	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HNMDAKOP_00391	7.16e-312	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HNMDAKOP_00392	2.07e-265	-	-	-	S	-	-	-	Protein of unknown function DUF262
HNMDAKOP_00393	1.9e-62	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HNMDAKOP_00394	8.68e-215	-	-	-	L	ko:K06400	-	ko00000	Recombinase
HNMDAKOP_00395	1.38e-30	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
HNMDAKOP_00396	6.23e-52	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
HNMDAKOP_00397	4.25e-145	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HNMDAKOP_00398	2.91e-147	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HNMDAKOP_00399	8.01e-125	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HNMDAKOP_00400	4.54e-45	-	-	-	C	-	-	-	Heavy-metal-associated domain
HNMDAKOP_00401	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HNMDAKOP_00402	2.98e-108	-	-	-	-	-	-	-	-
HNMDAKOP_00403	8.32e-79	-	-	-	-	-	-	-	-
HNMDAKOP_00415	1.83e-279	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
HNMDAKOP_00416	1.8e-247	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HNMDAKOP_00417	4.47e-232	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HNMDAKOP_00418	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HNMDAKOP_00419	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HNMDAKOP_00420	8.64e-153	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HNMDAKOP_00421	1.38e-138	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HNMDAKOP_00422	3.54e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNMDAKOP_00423	1.49e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HNMDAKOP_00424	1.45e-187	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HNMDAKOP_00425	1.16e-187	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HNMDAKOP_00426	1.02e-48	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
HNMDAKOP_00427	1.05e-212	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HNMDAKOP_00428	6.22e-73	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HNMDAKOP_00429	3.35e-147	-	-	-	K	-	-	-	SIS domain
HNMDAKOP_00430	5.98e-212	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HNMDAKOP_00431	5.55e-47	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HNMDAKOP_00432	1.67e-57	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HNMDAKOP_00433	6.11e-98	-	-	-	K	-	-	-	histone acetyltransferase HPA2 and related acetyltransferases
HNMDAKOP_00435	2.76e-73	-	-	-	L	-	-	-	Transposase
HNMDAKOP_00436	7.47e-105	-	-	-	L	-	-	-	Transposase
HNMDAKOP_00439	3.45e-16	-	-	-	S	-	-	-	ORF located using Blastx
HNMDAKOP_00443	1.22e-275	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HNMDAKOP_00444	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HNMDAKOP_00445	2.12e-144	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HNMDAKOP_00446	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HNMDAKOP_00447	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HNMDAKOP_00448	3.04e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HNMDAKOP_00449	1.33e-165	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HNMDAKOP_00450	1.38e-174	-	-	-	-	-	-	-	-
HNMDAKOP_00451	1.31e-184	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HNMDAKOP_00452	1.04e-215	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HNMDAKOP_00453	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HNMDAKOP_00454	3.79e-221	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HNMDAKOP_00455	2.04e-58	-	-	-	-	-	-	-	-
HNMDAKOP_00456	6.92e-15	-	-	-	K	-	-	-	Sigma-54 interaction domain
HNMDAKOP_00457	8.68e-35	-	-	-	K	-	-	-	Sigma-54 interaction domain
HNMDAKOP_00458	3.51e-59	-	-	-	K	-	-	-	Sigma-54 interaction domain
HNMDAKOP_00460	9.76e-120	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HNMDAKOP_00461	1.63e-156	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
HNMDAKOP_00462	3.16e-120	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HNMDAKOP_00463	5.49e-102	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HNMDAKOP_00464	1.42e-131	-	-	-	P	-	-	-	Voltage gated chloride channel
HNMDAKOP_00465	2.14e-117	-	-	-	P	-	-	-	Voltage gated chloride channel
HNMDAKOP_00466	1.36e-243	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HNMDAKOP_00467	8.57e-128	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HNMDAKOP_00468	2.8e-206	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HNMDAKOP_00469	2.33e-80	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
HNMDAKOP_00470	4.01e-184	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HNMDAKOP_00471	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HNMDAKOP_00472	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HNMDAKOP_00473	3.53e-100	-	-	-	K	-	-	-	acetyltransferase
HNMDAKOP_00474	1.32e-179	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HNMDAKOP_00475	1.9e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1440)
HNMDAKOP_00476	2.7e-150	-	-	-	S	-	-	-	hydrolase
HNMDAKOP_00477	7.19e-196	-	-	-	K	-	-	-	Transcriptional regulator
HNMDAKOP_00480	7.95e-307	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HNMDAKOP_00481	5.55e-168	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
HNMDAKOP_00482	3.14e-94	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HNMDAKOP_00483	1.17e-136	-	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HNMDAKOP_00484	4.82e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
HNMDAKOP_00485	7.81e-108	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HNMDAKOP_00486	4.27e-66	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HNMDAKOP_00487	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HNMDAKOP_00488	2.08e-51	-	-	-	-	-	-	-	-
HNMDAKOP_00489	3.74e-157	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	CAT RNA binding domain
HNMDAKOP_00490	3.41e-73	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HNMDAKOP_00491	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
HNMDAKOP_00492	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HNMDAKOP_00493	0.000356	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HNMDAKOP_00494	1.01e-162	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HNMDAKOP_00495	1.64e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
HNMDAKOP_00496	1.95e-137	-	-	-	E	-	-	-	Phospholipase B
HNMDAKOP_00497	1.86e-69	-	-	-	E	-	-	-	Phospholipase B
HNMDAKOP_00498	1.62e-54	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HNMDAKOP_00499	3.96e-216	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HNMDAKOP_00500	1.55e-305	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
HNMDAKOP_00501	2.92e-09	-	-	-	E	-	-	-	amino acid
HNMDAKOP_00502	8.98e-262	-	-	-	E	-	-	-	amino acid
HNMDAKOP_00503	1.13e-272	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HNMDAKOP_00504	2.73e-46	-	-	-	-	-	-	-	-
HNMDAKOP_00505	8.81e-89	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HNMDAKOP_00506	3.03e-86	-	-	-	-	-	-	-	-
HNMDAKOP_00507	2.08e-264	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HNMDAKOP_00509	2.29e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_00510	2.01e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HNMDAKOP_00511	2.45e-43	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
HNMDAKOP_00512	5.81e-57	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
HNMDAKOP_00513	7.88e-153	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
HNMDAKOP_00514	2.52e-85	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HNMDAKOP_00515	2.85e-195	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HNMDAKOP_00516	6.24e-33	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HNMDAKOP_00517	2.27e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HNMDAKOP_00518	3.45e-156	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HNMDAKOP_00519	1.33e-191	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HNMDAKOP_00520	1.43e-86	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HNMDAKOP_00521	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HNMDAKOP_00522	6.31e-226	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HNMDAKOP_00523	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HNMDAKOP_00524	8.55e-55	-	-	-	E	-	-	-	Peptidase family C69
HNMDAKOP_00525	1.56e-47	-	-	-	E	-	-	-	Peptidase family C69
HNMDAKOP_00526	1.55e-45	-	-	-	E	-	-	-	Peptidase family C69
HNMDAKOP_00527	6.59e-276	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HNMDAKOP_00528	5.81e-37	-	-	-	S	-	-	-	Alpha beta hydrolase
HNMDAKOP_00529	2.37e-96	-	-	-	S	-	-	-	Alpha beta hydrolase
HNMDAKOP_00530	1.47e-87	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HNMDAKOP_00531	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_00532	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HNMDAKOP_00533	2.21e-188	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HNMDAKOP_00534	8.05e-171	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_00535	3.69e-192	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HNMDAKOP_00536	1.01e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HNMDAKOP_00537	6.53e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HNMDAKOP_00538	3.97e-84	-	-	-	-	-	-	-	-
HNMDAKOP_00539	2.73e-32	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HNMDAKOP_00540	1.92e-146	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HNMDAKOP_00541	4.58e-10	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HNMDAKOP_00542	4.11e-114	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HNMDAKOP_00543	3.74e-70	-	-	-	K	-	-	-	Virulence activator alpha C-term
HNMDAKOP_00544	3.2e-107	-	-	-	S	-	-	-	Putative adhesin
HNMDAKOP_00547	2.24e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HNMDAKOP_00549	2.04e-48	-	-	-	S	-	-	-	CAAX protease self-immunity
HNMDAKOP_00550	3.13e-139	-	-	-	S	-	-	-	CAAX protease self-immunity
HNMDAKOP_00551	2.72e-69	-	-	-	S	-	-	-	Enterocin A Immunity
HNMDAKOP_00553	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HNMDAKOP_00554	7.77e-198	-	-	-	S	-	-	-	Phospholipase, patatin family
HNMDAKOP_00555	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HNMDAKOP_00556	6.55e-166	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_00557	3.77e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HNMDAKOP_00558	1.07e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HNMDAKOP_00559	2.42e-216	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HNMDAKOP_00560	4.83e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HNMDAKOP_00561	2.22e-189	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNMDAKOP_00562	9.79e-181	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNMDAKOP_00563	1.67e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HNMDAKOP_00564	1.48e-77	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNMDAKOP_00565	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HNMDAKOP_00566	1.98e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HNMDAKOP_00567	7.82e-211	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HNMDAKOP_00568	1.1e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HNMDAKOP_00569	3.8e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HNMDAKOP_00570	1.39e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HNMDAKOP_00571	8.41e-67	-	-	-	S	-	-	-	Enterocin A Immunity
HNMDAKOP_00572	5.83e-178	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HNMDAKOP_00573	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HNMDAKOP_00574	8.04e-150	-	-	-	C	-	-	-	nitroreductase
HNMDAKOP_00575	1.09e-15	-	-	-	-	-	-	-	-
HNMDAKOP_00576	1.26e-136	-	-	-	-	-	-	-	-
HNMDAKOP_00577	5.47e-299	yhdP	-	-	S	-	-	-	Transporter associated domain
HNMDAKOP_00578	2.11e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HNMDAKOP_00579	1.97e-294	-	-	-	E	ko:K03294	-	ko00000	amino acid
HNMDAKOP_00580	7.47e-173	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HNMDAKOP_00581	2.76e-271	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HNMDAKOP_00582	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMDAKOP_00585	7.09e-273	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HNMDAKOP_00586	3.07e-114	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HNMDAKOP_00587	1.94e-100	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HNMDAKOP_00588	9.94e-206	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HNMDAKOP_00589	1.92e-208	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HNMDAKOP_00590	4.95e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HNMDAKOP_00591	6.12e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_00592	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HNMDAKOP_00593	3.07e-89	-	-	-	O	-	-	-	OsmC-like protein
HNMDAKOP_00594	3.92e-103	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HNMDAKOP_00595	6.78e-60	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HNMDAKOP_00596	4.05e-147	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HNMDAKOP_00597	1.01e-149	dltr	-	-	K	-	-	-	response regulator
HNMDAKOP_00598	4.12e-287	sptS	-	-	T	-	-	-	Histidine kinase
HNMDAKOP_00599	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HNMDAKOP_00600	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HNMDAKOP_00601	1.75e-181	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HNMDAKOP_00603	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HNMDAKOP_00604	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HNMDAKOP_00605	5.68e-91	-	-	-	-	-	-	-	-
HNMDAKOP_00606	2.58e-135	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HNMDAKOP_00607	7.76e-188	-	-	-	M	-	-	-	Glycosyl transferase family 2
HNMDAKOP_00608	1.79e-119	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HNMDAKOP_00609	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HNMDAKOP_00610	3.24e-102	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HNMDAKOP_00611	9.39e-79	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HNMDAKOP_00612	1.09e-203	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HNMDAKOP_00613	1.22e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HNMDAKOP_00614	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HNMDAKOP_00615	9.68e-221	-	-	-	I	-	-	-	Carboxylesterase family
HNMDAKOP_00616	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HNMDAKOP_00617	4.87e-155	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HNMDAKOP_00618	8.76e-104	-	-	-	-	-	-	-	-
HNMDAKOP_00619	1.08e-183	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HNMDAKOP_00620	6.76e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HNMDAKOP_00621	8.45e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HNMDAKOP_00622	6.8e-17	-	-	-	-	-	-	-	-
HNMDAKOP_00623	1.09e-268	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HNMDAKOP_00624	4.65e-193	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNMDAKOP_00625	1.28e-77	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HNMDAKOP_00626	1.67e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HNMDAKOP_00627	9.89e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HNMDAKOP_00628	1.5e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HNMDAKOP_00629	1.73e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HNMDAKOP_00630	7.32e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HNMDAKOP_00631	1e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HNMDAKOP_00632	3.39e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HNMDAKOP_00633	4.56e-316	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNMDAKOP_00634	9.19e-45	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNMDAKOP_00635	8.46e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HNMDAKOP_00636	3.43e-195	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HNMDAKOP_00637	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HNMDAKOP_00638	7.04e-63	-	-	-	-	-	-	-	-
HNMDAKOP_00639	8.48e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HNMDAKOP_00640	2.72e-42	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HNMDAKOP_00641	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNMDAKOP_00642	1.32e-221	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HNMDAKOP_00643	1.07e-301	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HNMDAKOP_00644	1.29e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HNMDAKOP_00645	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HNMDAKOP_00646	5.08e-206	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HNMDAKOP_00647	4.51e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HNMDAKOP_00648	3.55e-155	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HNMDAKOP_00649	6.36e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HNMDAKOP_00650	4.8e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HNMDAKOP_00651	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HNMDAKOP_00652	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HNMDAKOP_00653	3.39e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HNMDAKOP_00654	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNMDAKOP_00655	2.01e-243	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HNMDAKOP_00656	7.66e-225	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HNMDAKOP_00657	2.49e-229	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HNMDAKOP_00658	2.5e-205	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HNMDAKOP_00659	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HNMDAKOP_00660	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HNMDAKOP_00661	7.14e-157	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HNMDAKOP_00662	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HNMDAKOP_00663	9.82e-238	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HNMDAKOP_00664	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HNMDAKOP_00665	3.48e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HNMDAKOP_00666	5.7e-291	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HNMDAKOP_00667	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HNMDAKOP_00668	2.07e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HNMDAKOP_00669	3.7e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HNMDAKOP_00670	2.61e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HNMDAKOP_00671	7.78e-150	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HNMDAKOP_00672	1.76e-94	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
HNMDAKOP_00673	3.57e-150	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HNMDAKOP_00674	3.19e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HNMDAKOP_00675	6.95e-45	ynzC	-	-	S	-	-	-	UPF0291 protein
HNMDAKOP_00676	4.85e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HNMDAKOP_00677	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HNMDAKOP_00678	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HNMDAKOP_00679	1.05e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HNMDAKOP_00680	5.54e-150	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HNMDAKOP_00681	6.03e-247	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HNMDAKOP_00682	7.4e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HNMDAKOP_00683	8.74e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HNMDAKOP_00684	1.01e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HNMDAKOP_00685	2.02e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HNMDAKOP_00686	3.42e-175	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HNMDAKOP_00687	6.8e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HNMDAKOP_00688	8.61e-291	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HNMDAKOP_00689	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HNMDAKOP_00690	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNMDAKOP_00691	6.59e-106	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HNMDAKOP_00692	5.25e-279	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HNMDAKOP_00693	1.79e-61	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HNMDAKOP_00694	3.8e-63	-	-	-	J	-	-	-	ribosomal protein
HNMDAKOP_00695	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HNMDAKOP_00696	4.75e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HNMDAKOP_00697	4.23e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HNMDAKOP_00698	4.41e-219	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HNMDAKOP_00701	4.24e-305	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HNMDAKOP_00702	1.09e-224	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HNMDAKOP_00714	2.33e-109	asp23	-	-	S	-	-	-	protein conserved in bacteria
HNMDAKOP_00715	1.92e-104	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HNMDAKOP_00716	1.28e-54	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HNMDAKOP_00717	0.0	-	-	-	E	-	-	-	amino acid
HNMDAKOP_00718	1.48e-172	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_00719	3.51e-182	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HNMDAKOP_00720	7.07e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HNMDAKOP_00721	1.17e-289	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HNMDAKOP_00722	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HNMDAKOP_00723	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HNMDAKOP_00724	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HNMDAKOP_00725	4.52e-198	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
HNMDAKOP_00726	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HNMDAKOP_00727	2.6e-181	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HNMDAKOP_00728	7.6e-105	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HNMDAKOP_00729	2.07e-42	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HNMDAKOP_00730	4.37e-45	-	-	-	-	-	-	-	-
HNMDAKOP_00731	4.59e-31	-	-	-	-	-	-	-	-
HNMDAKOP_00732	4.7e-98	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HNMDAKOP_00733	2.1e-46	-	-	-	-	-	-	-	-
HNMDAKOP_00734	1.32e-254	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HNMDAKOP_00735	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HNMDAKOP_00736	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HNMDAKOP_00737	1.78e-123	-	-	-	-	-	-	-	-
HNMDAKOP_00738	1.06e-86	-	-	-	F	-	-	-	adenylate kinase activity
HNMDAKOP_00739	9.4e-93	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNMDAKOP_00740	1.22e-134	-	-	-	P	-	-	-	Belongs to the major facilitator superfamily
HNMDAKOP_00741	5.45e-132	XK27_07210	-	-	S	-	-	-	B3 4 domain
HNMDAKOP_00742	1.35e-109	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HNMDAKOP_00743	5.18e-152	-	-	-	S	-	-	-	Membrane
HNMDAKOP_00744	1.47e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HNMDAKOP_00745	2.57e-133	-	-	-	K	-	-	-	transcriptional regulator
HNMDAKOP_00747	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HNMDAKOP_00748	1.04e-67	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HNMDAKOP_00749	1.12e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HNMDAKOP_00750	9.24e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HNMDAKOP_00751	5.98e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNMDAKOP_00752	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HNMDAKOP_00753	4.17e-90	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HNMDAKOP_00754	3.93e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HNMDAKOP_00755	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HNMDAKOP_00756	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HNMDAKOP_00757	1.14e-196	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HNMDAKOP_00758	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HNMDAKOP_00759	3.34e-286	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HNMDAKOP_00760	5.55e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HNMDAKOP_00761	1.05e-146	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HNMDAKOP_00762	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HNMDAKOP_00763	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HNMDAKOP_00764	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HNMDAKOP_00765	4.41e-220	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HNMDAKOP_00766	1.26e-219	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNMDAKOP_00767	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HNMDAKOP_00768	2.23e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HNMDAKOP_00769	1.22e-48	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HNMDAKOP_00770	1.69e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HNMDAKOP_00771	1.54e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNMDAKOP_00772	2.92e-185	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HNMDAKOP_00773	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNMDAKOP_00774	1.08e-227	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HNMDAKOP_00775	1.2e-126	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HNMDAKOP_00776	9.68e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
HNMDAKOP_00777	2.46e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HNMDAKOP_00778	4.22e-149	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
HNMDAKOP_00780	7.7e-149	-	-	-	-	-	-	-	-
HNMDAKOP_00781	1.83e-198	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HNMDAKOP_00782	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HNMDAKOP_00783	2.31e-67	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMDAKOP_00784	2.44e-34	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMDAKOP_00785	4.85e-30	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMDAKOP_00786	3.19e-95	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMDAKOP_00787	8.12e-69	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HNMDAKOP_00788	6e-48	-	-	-	-	-	-	-	-
HNMDAKOP_00789	1.76e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HNMDAKOP_00790	1.82e-171	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HNMDAKOP_00791	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HNMDAKOP_00792	2.79e-43	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HNMDAKOP_00793	1.9e-164	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HNMDAKOP_00794	1.27e-306	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMDAKOP_00795	5.53e-106	-	-	-	-	-	-	-	-
HNMDAKOP_00796	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HNMDAKOP_00797	5.25e-97	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HNMDAKOP_00798	1.1e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HNMDAKOP_00799	1.14e-60	-	-	-	-	-	-	-	-
HNMDAKOP_00800	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HNMDAKOP_00801	5.22e-54	-	-	-	K	-	-	-	sequence-specific DNA binding
HNMDAKOP_00802	3.07e-39	-	-	-	S	-	-	-	Motility quorum-sensing regulator, toxin of MqsA
HNMDAKOP_00803	4.68e-153	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HNMDAKOP_00804	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HNMDAKOP_00806	2.32e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HNMDAKOP_00807	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HNMDAKOP_00808	1.71e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HNMDAKOP_00809	4.69e-261	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HNMDAKOP_00810	1.54e-214	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
HNMDAKOP_00811	4.46e-195	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HNMDAKOP_00812	2.42e-149	-	-	-	-	-	-	-	-
HNMDAKOP_00813	2.82e-123	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HNMDAKOP_00814	4.35e-13	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HNMDAKOP_00815	2.6e-16	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HNMDAKOP_00816	1.05e-225	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HNMDAKOP_00817	9.65e-95	-	-	-	S	-	-	-	GtrA-like protein
HNMDAKOP_00818	6.23e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNMDAKOP_00819	0.0	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HNMDAKOP_00820	2.61e-110	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HNMDAKOP_00822	2.22e-13	-	-	-	-	-	-	-	-
HNMDAKOP_00823	3.29e-06	-	-	-	D	-	-	-	nuclear chromosome segregation
HNMDAKOP_00825	1.4e-64	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HNMDAKOP_00827	2.23e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HNMDAKOP_00828	5.45e-94	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HNMDAKOP_00829	1.86e-181	-	-	-	-	-	-	-	-
HNMDAKOP_00830	8.57e-175	-	-	-	-	-	-	-	-
HNMDAKOP_00831	2.19e-223	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HNMDAKOP_00832	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HNMDAKOP_00833	3.79e-183	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HNMDAKOP_00834	9.06e-264	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HNMDAKOP_00835	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HNMDAKOP_00836	6.57e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HNMDAKOP_00837	3.17e-33	-	-	-	-	-	-	-	-
HNMDAKOP_00838	3.79e-164	-	-	-	-	-	-	-	-
HNMDAKOP_00839	1.7e-92	-	-	-	-	-	-	-	-
HNMDAKOP_00840	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HNMDAKOP_00841	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HNMDAKOP_00842	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HNMDAKOP_00843	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HNMDAKOP_00844	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HNMDAKOP_00845	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HNMDAKOP_00846	1.92e-211	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HNMDAKOP_00847	3.13e-173	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HNMDAKOP_00848	4.6e-288	-	-	-	D	-	-	-	transport
HNMDAKOP_00849	6.65e-235	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
HNMDAKOP_00850	2.27e-287	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
HNMDAKOP_00851	5.78e-288	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HNMDAKOP_00852	3.6e-133	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HNMDAKOP_00853	6.16e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HNMDAKOP_00854	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HNMDAKOP_00855	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HNMDAKOP_00856	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HNMDAKOP_00857	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HNMDAKOP_00858	9.7e-109	-	-	-	-	-	-	-	-
HNMDAKOP_00859	8.69e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HNMDAKOP_00860	2.02e-168	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HNMDAKOP_00861	1.74e-179	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HNMDAKOP_00862	4.37e-213	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HNMDAKOP_00864	6.03e-114	usp5	-	-	T	-	-	-	universal stress protein
HNMDAKOP_00865	8.74e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HNMDAKOP_00866	3.95e-166	-	-	-	K	-	-	-	UTRA domain
HNMDAKOP_00867	5.05e-128	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HNMDAKOP_00868	1.56e-113	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HNMDAKOP_00869	2.47e-257	-	-	-	S	-	-	-	zinc-ribbon domain
HNMDAKOP_00870	3.64e-86	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HNMDAKOP_00871	1.02e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HNMDAKOP_00872	1.63e-190	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HNMDAKOP_00873	1.13e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HNMDAKOP_00874	5.12e-289	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HNMDAKOP_00875	2.56e-270	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
HNMDAKOP_00876	1.95e-160	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HNMDAKOP_00877	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HNMDAKOP_00878	2.82e-195	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HNMDAKOP_00879	6.08e-154	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HNMDAKOP_00880	5.77e-216	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HNMDAKOP_00881	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HNMDAKOP_00882	1.62e-132	-	-	-	-	-	-	-	-
HNMDAKOP_00883	1.85e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HNMDAKOP_00884	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HNMDAKOP_00885	1.14e-161	-	-	-	-	-	-	-	-
HNMDAKOP_00886	2.45e-115	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HNMDAKOP_00887	1.41e-303	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HNMDAKOP_00888	1.23e-229	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNMDAKOP_00889	1.13e-81	-	-	-	-	-	-	-	-
HNMDAKOP_00890	1.63e-159	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HNMDAKOP_00891	4.36e-201	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HNMDAKOP_00892	9.58e-219	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HNMDAKOP_00894	8.4e-178	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNMDAKOP_00895	1.95e-220	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HNMDAKOP_00896	1.73e-157	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HNMDAKOP_00897	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNMDAKOP_00898	1.28e-103	-	-	-	-	-	-	-	-
HNMDAKOP_00899	1.5e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HNMDAKOP_00900	8.3e-111	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HNMDAKOP_00901	8.06e-164	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HNMDAKOP_00902	1.88e-80	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HNMDAKOP_00903	1.03e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HNMDAKOP_00904	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HNMDAKOP_00905	3.97e-176	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_00906	1.62e-26	-	-	-	-	-	-	-	-
HNMDAKOP_00907	2.24e-207	-	-	-	L	-	-	-	HNH nucleases
HNMDAKOP_00908	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HNMDAKOP_00909	8.65e-255	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HNMDAKOP_00910	5.13e-303	-	-	-	M	-	-	-	Glycosyl transferase
HNMDAKOP_00912	1.38e-139	-	-	-	-	-	-	-	-
HNMDAKOP_00913	1.14e-23	-	-	-	-	-	-	-	-
HNMDAKOP_00914	6.69e-84	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HNMDAKOP_00915	8.61e-236	ysdE	-	-	P	-	-	-	Citrate transporter
HNMDAKOP_00916	8.93e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HNMDAKOP_00917	2.38e-191	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HNMDAKOP_00918	3.05e-208	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HNMDAKOP_00919	9.27e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HNMDAKOP_00920	8.34e-311	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_00921	2.11e-140	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HNMDAKOP_00922	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HNMDAKOP_00923	2.43e-239	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HNMDAKOP_00924	4.15e-189	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HNMDAKOP_00925	7.09e-185	yycI	-	-	S	-	-	-	YycH protein
HNMDAKOP_00926	8.65e-310	yycH	-	-	S	-	-	-	YycH protein
HNMDAKOP_00927	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HNMDAKOP_00928	2.49e-166	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HNMDAKOP_00929	1.26e-245	flp	-	-	V	-	-	-	Beta-lactamase
HNMDAKOP_00930	1.74e-179	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
HNMDAKOP_00931	1.62e-11	-	-	-	K	ko:K03830	-	ko00000,ko01000	COG COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNMDAKOP_00933	4.01e-200	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HNMDAKOP_00934	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HNMDAKOP_00935	1.29e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HNMDAKOP_00936	4.09e-272	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HNMDAKOP_00937	0.0	yhaN	-	-	L	-	-	-	AAA domain
HNMDAKOP_00938	5.07e-236	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HNMDAKOP_00939	1.76e-202	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HNMDAKOP_00940	2.95e-48	-	-	-	S	-	-	-	YtxH-like protein
HNMDAKOP_00941	2.56e-85	-	-	-	-	-	-	-	-
HNMDAKOP_00942	9.69e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HNMDAKOP_00943	5.64e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_00944	1.58e-283	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HNMDAKOP_00945	1.03e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HNMDAKOP_00946	1.56e-77	-	-	-	-	-	-	-	-
HNMDAKOP_00947	1.52e-68	ytpP	-	-	CO	-	-	-	Thioredoxin
HNMDAKOP_00948	6.93e-154	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNMDAKOP_00950	7.62e-165	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HNMDAKOP_00951	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
HNMDAKOP_00952	9.37e-228	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HNMDAKOP_00953	2.51e-120	-	-	-	S	-	-	-	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
HNMDAKOP_00954	4.11e-248	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMDAKOP_00955	1.7e-149	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HNMDAKOP_00956	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HNMDAKOP_00957	8.54e-80	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HNMDAKOP_00958	1.33e-53	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HNMDAKOP_00959	1.42e-38	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HNMDAKOP_00960	5.72e-22	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HNMDAKOP_00961	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNMDAKOP_00962	4.18e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HNMDAKOP_00963	1.99e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HNMDAKOP_00964	3.43e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HNMDAKOP_00965	1.23e-311	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HNMDAKOP_00966	5.93e-206	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HNMDAKOP_00967	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HNMDAKOP_00968	7.68e-71	-	-	-	K	-	-	-	LytTr DNA-binding domain
HNMDAKOP_00969	3.19e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HNMDAKOP_00970	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HNMDAKOP_00971	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HNMDAKOP_00972	3.54e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HNMDAKOP_00973	1.08e-130	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HNMDAKOP_00974	6.88e-16	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HNMDAKOP_00975	1.57e-113	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HNMDAKOP_00976	3.91e-269	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HNMDAKOP_00977	1.78e-148	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HNMDAKOP_00978	3.62e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HNMDAKOP_00979	4.36e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HNMDAKOP_00980	2.68e-275	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HNMDAKOP_00981	2.03e-118	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HNMDAKOP_00982	1.89e-169	csrR	-	-	K	-	-	-	response regulator
HNMDAKOP_00983	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HNMDAKOP_00984	1.76e-212	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNMDAKOP_00985	9.98e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HNMDAKOP_00986	1.01e-174	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNMDAKOP_00987	4.83e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HNMDAKOP_00988	5.23e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HNMDAKOP_00989	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNMDAKOP_00990	1.51e-259	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNMDAKOP_00991	5.34e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HNMDAKOP_00992	0.0	-	-	-	S	-	-	-	membrane
HNMDAKOP_00993	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HNMDAKOP_00994	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HNMDAKOP_00995	4.25e-122	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HNMDAKOP_00996	1.66e-147	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HNMDAKOP_00997	3.31e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HNMDAKOP_00998	2.44e-75	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HNMDAKOP_00999	6.85e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HNMDAKOP_01000	5.99e-214	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HNMDAKOP_01001	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HNMDAKOP_01002	6.38e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HNMDAKOP_01003	1.29e-190	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HNMDAKOP_01005	1.56e-229	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HNMDAKOP_01006	1.27e-270	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HNMDAKOP_01007	2.04e-274	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HNMDAKOP_01008	8.05e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HNMDAKOP_01009	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNMDAKOP_01010	3.01e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HNMDAKOP_01011	1.6e-145	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HNMDAKOP_01012	3.1e-112	-	-	-	-	-	-	-	-
HNMDAKOP_01013	4.87e-101	-	-	-	-	-	-	-	-
HNMDAKOP_01014	2.14e-198	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HNMDAKOP_01015	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HNMDAKOP_01016	2.17e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HNMDAKOP_01017	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HNMDAKOP_01018	1.02e-34	-	-	-	-	-	-	-	-
HNMDAKOP_01019	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HNMDAKOP_01020	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HNMDAKOP_01021	1.31e-84	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HNMDAKOP_01022	1.57e-151	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HNMDAKOP_01023	6.65e-204	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HNMDAKOP_01024	4.75e-134	yjbH	-	-	Q	-	-	-	Thioredoxin
HNMDAKOP_01025	5.69e-140	-	-	-	S	-	-	-	CYTH
HNMDAKOP_01026	1.4e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HNMDAKOP_01027	1.34e-192	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNMDAKOP_01028	2.98e-215	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HNMDAKOP_01029	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HNMDAKOP_01030	1.89e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HNMDAKOP_01031	1.18e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HNMDAKOP_01032	1.51e-82	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HNMDAKOP_01033	6.98e-266	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HNMDAKOP_01034	8e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HNMDAKOP_01035	6.55e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HNMDAKOP_01036	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HNMDAKOP_01037	2.65e-287	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HNMDAKOP_01038	9.63e-289	ymfH	-	-	S	-	-	-	Peptidase M16
HNMDAKOP_01039	5.82e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HNMDAKOP_01040	5.69e-176	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HNMDAKOP_01041	3.1e-125	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNMDAKOP_01042	1.95e-247	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HNMDAKOP_01043	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HNMDAKOP_01044	9.48e-262	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HNMDAKOP_01045	7.74e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HNMDAKOP_01046	1.91e-280	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HNMDAKOP_01047	6.9e-158	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HNMDAKOP_01048	1.62e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HNMDAKOP_01049	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HNMDAKOP_01050	1.19e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HNMDAKOP_01051	2.63e-40	-	-	-	-	-	-	-	-
HNMDAKOP_01052	4.58e-220	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HNMDAKOP_01053	1.2e-199	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HNMDAKOP_01054	5.49e-238	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HNMDAKOP_01055	6.05e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HNMDAKOP_01056	2.44e-241	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HNMDAKOP_01057	3.86e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HNMDAKOP_01058	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HNMDAKOP_01059	7.52e-239	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HNMDAKOP_01060	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HNMDAKOP_01061	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HNMDAKOP_01062	1.19e-280	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HNMDAKOP_01063	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HNMDAKOP_01064	1.31e-244	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HNMDAKOP_01065	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HNMDAKOP_01066	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HNMDAKOP_01067	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HNMDAKOP_01068	2.04e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HNMDAKOP_01069	4.53e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HNMDAKOP_01070	6.27e-247	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HNMDAKOP_01071	2.02e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HNMDAKOP_01072	3.74e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HNMDAKOP_01073	0.0	ycaM	-	-	E	-	-	-	amino acid
HNMDAKOP_01075	1.07e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HNMDAKOP_01076	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HNMDAKOP_01077	2.01e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HNMDAKOP_01078	5.9e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HNMDAKOP_01079	1.68e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNMDAKOP_01080	7.52e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HNMDAKOP_01081	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HNMDAKOP_01082	1.71e-100	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HNMDAKOP_01083	8.94e-135	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HNMDAKOP_01084	7.71e-111	-	-	-	-	-	-	-	-
HNMDAKOP_01085	5.96e-122	-	-	-	-	-	-	-	-
HNMDAKOP_01086	1.19e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HNMDAKOP_01087	1.02e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HNMDAKOP_01088	6.09e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HNMDAKOP_01089	1.75e-110	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HNMDAKOP_01090	9.09e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HNMDAKOP_01091	5.31e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HNMDAKOP_01092	2.82e-259	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HNMDAKOP_01093	2.51e-172	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HNMDAKOP_01094	2.65e-176	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HNMDAKOP_01095	1.64e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HNMDAKOP_01096	1.5e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNMDAKOP_01097	6.03e-222	ybbR	-	-	S	-	-	-	YbbR-like protein
HNMDAKOP_01098	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HNMDAKOP_01099	1.39e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HNMDAKOP_01100	6.06e-85	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNMDAKOP_01101	2.48e-80	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNMDAKOP_01102	2.73e-253	-	-	-	S	-	-	-	Putative adhesin
HNMDAKOP_01103	1.15e-146	-	-	-	-	-	-	-	-
HNMDAKOP_01104	3.84e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HNMDAKOP_01105	3.31e-206	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HNMDAKOP_01106	7.12e-275	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNMDAKOP_01107	1.07e-124	-	-	-	S	-	-	-	VanZ like family
HNMDAKOP_01108	6.1e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HNMDAKOP_01109	8.65e-228	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HNMDAKOP_01110	2.45e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HNMDAKOP_01111	9.23e-55	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
HNMDAKOP_01112	4.63e-76	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HNMDAKOP_01114	1.06e-109	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HNMDAKOP_01115	9.07e-234	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HNMDAKOP_01116	1.12e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNMDAKOP_01118	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HNMDAKOP_01119	1.34e-124	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HNMDAKOP_01120	5.23e-130	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HNMDAKOP_01121	5.61e-59	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HNMDAKOP_01122	3.77e-37	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HNMDAKOP_01123	2.96e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HNMDAKOP_01124	7.69e-87	-	-	-	S	-	-	-	SdpI/YhfL protein family
HNMDAKOP_01125	8.64e-163	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HNMDAKOP_01126	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HNMDAKOP_01127	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HNMDAKOP_01128	2.94e-134	vanZ	-	-	V	-	-	-	VanZ like family
HNMDAKOP_01129	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HNMDAKOP_01130	1.31e-54	-	-	-	EGP	-	-	-	Major Facilitator
HNMDAKOP_01131	2.78e-117	-	-	-	EGP	-	-	-	Major Facilitator
HNMDAKOP_01132	4.56e-89	-	-	-	-	-	-	-	-
HNMDAKOP_01135	5.12e-243	ampC	-	-	V	-	-	-	Beta-lactamase
HNMDAKOP_01136	2.29e-59	-	-	-	I	-	-	-	Membrane-associated phospholipid phosphatase
HNMDAKOP_01137	5.77e-81	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
HNMDAKOP_01138	1.01e-227	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HNMDAKOP_01139	8.39e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HNMDAKOP_01140	2.73e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HNMDAKOP_01141	9.44e-188	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HNMDAKOP_01142	1.14e-123	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HNMDAKOP_01143	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HNMDAKOP_01144	1.15e-73	-	-	-	-	-	-	-	-
HNMDAKOP_01145	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HNMDAKOP_01146	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HNMDAKOP_01147	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
HNMDAKOP_01148	4.23e-222	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HNMDAKOP_01149	7e-267	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HNMDAKOP_01150	8.01e-66	-	-	-	-	-	-	-	-
HNMDAKOP_01151	2.92e-37	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HNMDAKOP_01152	8.14e-176	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HNMDAKOP_01153	3.98e-276	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNMDAKOP_01154	8.48e-151	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HNMDAKOP_01155	2.39e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HNMDAKOP_01156	1.05e-89	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HNMDAKOP_01157	8.93e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HNMDAKOP_01158	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNMDAKOP_01159	1.09e-117	cvpA	-	-	S	-	-	-	Colicin V production protein
HNMDAKOP_01160	3.49e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HNMDAKOP_01161	4.81e-94	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HNMDAKOP_01162	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HNMDAKOP_01163	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HNMDAKOP_01164	2.18e-292	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HNMDAKOP_01165	3.56e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HNMDAKOP_01166	2.84e-264	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNMDAKOP_01167	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HNMDAKOP_01168	1.47e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HNMDAKOP_01169	5.68e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HNMDAKOP_01170	2.44e-129	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HNMDAKOP_01171	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HNMDAKOP_01172	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HNMDAKOP_01173	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
HNMDAKOP_01175	1.95e-74	-	-	-	-	-	-	-	-
HNMDAKOP_01176	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HNMDAKOP_01177	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HNMDAKOP_01178	3.8e-140	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HNMDAKOP_01179	2.07e-15	ansR	-	-	K	-	-	-	Transcriptional regulator
HNMDAKOP_01180	2.72e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
HNMDAKOP_01183	7.46e-07	-	-	-	-	-	-	-	-
HNMDAKOP_01184	2.89e-34	-	-	-	-	-	-	-	-
HNMDAKOP_01186	4.04e-06	-	3.1.3.16	-	-	ko:K01090	-	ko00000,ko01000	-
HNMDAKOP_01190	9.61e-168	-	-	-	S	-	-	-	membrane
HNMDAKOP_01191	5.72e-104	-	-	-	K	-	-	-	LytTr DNA-binding domain
HNMDAKOP_01192	1.88e-131	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HNMDAKOP_01193	6.68e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HNMDAKOP_01194	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HNMDAKOP_01195	3.53e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HNMDAKOP_01196	2.1e-19	-	-	-	-	-	-	-	-
HNMDAKOP_01197	2.5e-34	-	-	-	-	-	-	-	-
HNMDAKOP_01198	1.24e-194	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HNMDAKOP_01199	3.14e-179	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HNMDAKOP_01200	1.22e-89	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HNMDAKOP_01201	1.5e-136	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HNMDAKOP_01202	4.63e-58	-	-	-	-	-	-	-	-
HNMDAKOP_01203	1.46e-55	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HNMDAKOP_01204	3e-309	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HNMDAKOP_01205	9.69e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HNMDAKOP_01206	2e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HNMDAKOP_01207	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HNMDAKOP_01208	5.73e-149	-	-	-	-	-	-	-	-
HNMDAKOP_01209	4.28e-196	-	-	-	-	-	-	-	-
HNMDAKOP_01210	2.43e-54	-	-	-	D	-	-	-	nuclear chromosome segregation
HNMDAKOP_01211	8.43e-216	-	-	-	D	-	-	-	nuclear chromosome segregation
HNMDAKOP_01212	1.67e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HNMDAKOP_01213	1.83e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HNMDAKOP_01214	5.86e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HNMDAKOP_01215	5.17e-103	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HNMDAKOP_01216	3.04e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HNMDAKOP_01217	1.45e-197	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HNMDAKOP_01218	3.33e-78	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HNMDAKOP_01219	7.4e-193	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HNMDAKOP_01220	1.24e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HNMDAKOP_01221	1.45e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HNMDAKOP_01222	1.76e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HNMDAKOP_01223	7.27e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HNMDAKOP_01224	3.83e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HNMDAKOP_01225	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNMDAKOP_01226	1.18e-109	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HNMDAKOP_01227	3.05e-60	-	-	-	S	-	-	-	Protein conserved in bacteria
HNMDAKOP_01228	5.71e-187	-	-	-	-	-	-	-	-
HNMDAKOP_01229	1.65e-31	-	-	-	-	-	-	-	-
HNMDAKOP_01230	6.45e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HNMDAKOP_01231	3.25e-44	-	-	-	-	-	-	-	-
HNMDAKOP_01232	8.99e-181	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
HNMDAKOP_01233	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HNMDAKOP_01234	1.78e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HNMDAKOP_01235	4.3e-183	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HNMDAKOP_01236	2.23e-150	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HNMDAKOP_01237	3.38e-140	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HNMDAKOP_01238	2.48e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HNMDAKOP_01239	1.89e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HNMDAKOP_01240	5.22e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HNMDAKOP_01241	8.06e-17	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HNMDAKOP_01242	1.48e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HNMDAKOP_01243	1.16e-240	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HNMDAKOP_01244	6.81e-291	-	-	-	G	-	-	-	Major Facilitator Superfamily
HNMDAKOP_01245	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HNMDAKOP_01246	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HNMDAKOP_01247	3.42e-45	-	-	-	-	-	-	-	-
HNMDAKOP_01248	4.19e-113	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
HNMDAKOP_01249	1.39e-180	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNMDAKOP_01250	5.57e-104	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HNMDAKOP_01251	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HNMDAKOP_01252	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HNMDAKOP_01253	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HNMDAKOP_01254	3.82e-133	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HNMDAKOP_01255	6.03e-42	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HNMDAKOP_01256	1.65e-20	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HNMDAKOP_01257	1.51e-152	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HNMDAKOP_01258	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HNMDAKOP_01259	2.51e-36	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HNMDAKOP_01260	3.94e-75	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
HNMDAKOP_01261	1.02e-139	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HNMDAKOP_01262	3.77e-47	-	-	-	L	-	-	-	transposase activity
HNMDAKOP_01263	1.99e-33	-	-	-	L	-	-	-	Transposase
HNMDAKOP_01264	3.51e-91	-	-	-	L	-	-	-	Transposase
HNMDAKOP_01265	8.3e-68	-	-	-	L	-	-	-	Transposase
HNMDAKOP_01266	4.01e-235	-	-	-	S	-	-	-	AAA domain
HNMDAKOP_01267	3.24e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HNMDAKOP_01268	8.33e-17	-	-	-	-	-	-	-	-
HNMDAKOP_01269	2.02e-52	-	-	-	-	-	-	-	-
HNMDAKOP_01270	2.29e-196	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HNMDAKOP_01271	2.14e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HNMDAKOP_01272	4.5e-166	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HNMDAKOP_01273	7.33e-141	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HNMDAKOP_01274	7.33e-190	-	-	-	GM	-	-	-	NmrA-like family
HNMDAKOP_01275	1.13e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HNMDAKOP_01276	1.08e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HNMDAKOP_01277	2.5e-189	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HNMDAKOP_01278	4.78e-179	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNMDAKOP_01279	1.25e-264	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HNMDAKOP_01280	4.68e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNMDAKOP_01281	5.03e-194	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNMDAKOP_01282	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HNMDAKOP_01283	7.63e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNMDAKOP_01284	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HNMDAKOP_01285	1.92e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HNMDAKOP_01286	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HNMDAKOP_01287	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HNMDAKOP_01288	4.87e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HNMDAKOP_01289	1.2e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HNMDAKOP_01290	5.78e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HNMDAKOP_01291	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HNMDAKOP_01292	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HNMDAKOP_01293	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HNMDAKOP_01294	1.24e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HNMDAKOP_01295	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HNMDAKOP_01296	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNMDAKOP_01297	6.1e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HNMDAKOP_01298	1.18e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HNMDAKOP_01299	6.02e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HNMDAKOP_01300	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HNMDAKOP_01301	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HNMDAKOP_01302	3e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HNMDAKOP_01303	8.71e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HNMDAKOP_01304	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HNMDAKOP_01305	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HNMDAKOP_01306	1.99e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HNMDAKOP_01307	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HNMDAKOP_01308	1.57e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HNMDAKOP_01309	1.77e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HNMDAKOP_01310	5.22e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HNMDAKOP_01311	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HNMDAKOP_01312	8.05e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HNMDAKOP_01313	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HNMDAKOP_01314	1.48e-127	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HNMDAKOP_01315	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNMDAKOP_01316	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNMDAKOP_01317	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HNMDAKOP_01320	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HNMDAKOP_01321	1.86e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNMDAKOP_01322	7.84e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HNMDAKOP_01323	0.0	-	-	-	S	-	-	-	membrane
HNMDAKOP_01324	0.0	-	-	-	S	-	-	-	membrane
HNMDAKOP_01325	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HNMDAKOP_01326	9.03e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HNMDAKOP_01327	3.15e-78	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
HNMDAKOP_01328	1.52e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HNMDAKOP_01329	2.98e-45	yabO	-	-	J	-	-	-	S4 domain protein
HNMDAKOP_01330	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HNMDAKOP_01331	1.55e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HNMDAKOP_01332	1.14e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HNMDAKOP_01333	2.59e-159	-	-	-	S	-	-	-	(CBS) domain
HNMDAKOP_01334	1.73e-271	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNMDAKOP_01335	1.14e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HNMDAKOP_01336	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HNMDAKOP_01337	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HNMDAKOP_01338	1.76e-91	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HNMDAKOP_01339	9.06e-233	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HNMDAKOP_01340	2.49e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HNMDAKOP_01341	2.75e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HNMDAKOP_01342	3.38e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HNMDAKOP_01343	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HNMDAKOP_01344	1.89e-295	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HNMDAKOP_01345	1.63e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HNMDAKOP_01346	9.91e-303	-	-	-	E	-	-	-	amino acid
HNMDAKOP_01347	5.52e-241	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HNMDAKOP_01348	2.22e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HNMDAKOP_01349	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HNMDAKOP_01350	8.1e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HNMDAKOP_01351	2.69e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HNMDAKOP_01352	3.28e-181	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HNMDAKOP_01353	5.27e-235	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HNMDAKOP_01354	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HNMDAKOP_01355	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HNMDAKOP_01356	2.09e-116	ymdB	-	-	S	-	-	-	Macro domain protein
HNMDAKOP_01357	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HNMDAKOP_01358	4.84e-160	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HNMDAKOP_01359	3.53e-276	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HNMDAKOP_01360	1.06e-198	-	-	-	-	-	-	-	-
HNMDAKOP_01361	5.24e-92	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
HNMDAKOP_01362	2.84e-197	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HNMDAKOP_01363	2.31e-195	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HNMDAKOP_01364	1.75e-17	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HNMDAKOP_01365	1.76e-139	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HNMDAKOP_01366	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HNMDAKOP_01367	9.42e-203	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNMDAKOP_01368	8.03e-160	-	-	-	-	-	-	-	-
HNMDAKOP_01369	1.32e-66	-	-	-	-	-	-	-	-
HNMDAKOP_01370	1.38e-176	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HNMDAKOP_01371	3.83e-177	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HNMDAKOP_01372	3.44e-146	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HNMDAKOP_01373	1.86e-141	-	-	-	G	-	-	-	phosphoglycerate mutase
HNMDAKOP_01374	9.8e-113	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HNMDAKOP_01375	9.3e-231	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HNMDAKOP_01376	2.68e-152	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_01377	1.4e-167	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HNMDAKOP_01378	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HNMDAKOP_01379	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HNMDAKOP_01380	3.9e-50	-	-	-	-	-	-	-	-
HNMDAKOP_01381	1.34e-138	-	-	-	K	-	-	-	WHG domain
HNMDAKOP_01382	2.49e-122	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HNMDAKOP_01383	1.81e-127	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HNMDAKOP_01384	2.58e-255	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HNMDAKOP_01385	2.4e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HNMDAKOP_01386	1.28e-225	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HNMDAKOP_01387	3.16e-125	cvpA	-	-	S	-	-	-	Colicin V production protein
HNMDAKOP_01388	1.68e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HNMDAKOP_01389	2.47e-195	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HNMDAKOP_01390	1.43e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HNMDAKOP_01391	9.01e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HNMDAKOP_01392	7.4e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HNMDAKOP_01393	7.69e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HNMDAKOP_01394	2.58e-189	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HNMDAKOP_01395	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_01396	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HNMDAKOP_01397	2.39e-156	vanR	-	-	K	-	-	-	response regulator
HNMDAKOP_01398	4.01e-261	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HNMDAKOP_01399	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HNMDAKOP_01400	4.33e-183	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HNMDAKOP_01401	1.25e-69	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_01402	1.16e-64	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_01403	5.77e-98	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HNMDAKOP_01404	9.22e-142	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HNMDAKOP_01405	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HNMDAKOP_01406	3.26e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HNMDAKOP_01407	7.29e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HNMDAKOP_01408	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HNMDAKOP_01409	1.42e-276	-	-	-	M	-	-	-	domain protein
HNMDAKOP_01410	1.67e-177	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HNMDAKOP_01411	1.07e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HNMDAKOP_01412	2.94e-206	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HNMDAKOP_01413	2.22e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HNMDAKOP_01414	6.98e-171	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HNMDAKOP_01415	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HNMDAKOP_01416	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HNMDAKOP_01417	1.03e-262	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HNMDAKOP_01418	4.11e-52	-	-	-	-	-	-	-	-
HNMDAKOP_01419	3.7e-79	-	-	-	-	-	-	-	-
HNMDAKOP_01420	0.0	-	-	-	S	-	-	-	ABC transporter
HNMDAKOP_01421	2.11e-175	-	-	-	S	-	-	-	Putative threonine/serine exporter
HNMDAKOP_01422	2.13e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HNMDAKOP_01423	3.02e-53	-	-	-	-	-	-	-	-
HNMDAKOP_01424	8.86e-78	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HNMDAKOP_01425	6.79e-105	-	-	-	-	-	-	-	-
HNMDAKOP_01426	1.49e-222	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNMDAKOP_01427	1.75e-39	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HNMDAKOP_01428	1.29e-141	-	-	-	-	-	-	-	-
HNMDAKOP_01429	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HNMDAKOP_01430	1.87e-58	-	-	-	-	-	-	-	-
HNMDAKOP_01431	4.8e-128	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HNMDAKOP_01432	2.45e-170	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HNMDAKOP_01433	4.97e-291	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HNMDAKOP_01434	3.69e-296	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HNMDAKOP_01435	0.0	-	-	-	E	-	-	-	Amino Acid
HNMDAKOP_01436	1.74e-168	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_01437	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HNMDAKOP_01438	1.39e-20	-	-	-	K	-	-	-	transcriptional regulator
HNMDAKOP_01439	2.96e-103	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
HNMDAKOP_01440	1.78e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HNMDAKOP_01441	2.66e-35	-	-	-	-	-	-	-	-
HNMDAKOP_01442	1.17e-68	-	-	-	-	-	-	-	-
HNMDAKOP_01443	7.97e-31	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HNMDAKOP_01444	2.73e-127	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HNMDAKOP_01445	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HNMDAKOP_01446	2.81e-165	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HNMDAKOP_01447	3.64e-182	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HNMDAKOP_01448	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HNMDAKOP_01450	1.9e-146	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HNMDAKOP_01451	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HNMDAKOP_01452	3.41e-157	-	-	-	S	-	-	-	Peptidase_C39 like family
HNMDAKOP_01453	1.05e-154	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HNMDAKOP_01454	9.55e-107	-	-	-	L	-	-	-	MgsA AAA+ ATPase C terminal
HNMDAKOP_01455	2.26e-302	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMDAKOP_01456	2.37e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HNMDAKOP_01457	7.58e-210	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HNMDAKOP_01458	3.23e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HNMDAKOP_01459	1.17e-196	-	-	-	EG	-	-	-	EamA-like transporter family
HNMDAKOP_01460	5.07e-300	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HNMDAKOP_01461	1.58e-209	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HNMDAKOP_01462	2.27e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HNMDAKOP_01463	1.56e-185	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HNMDAKOP_01464	4.97e-79	-	-	-	-	-	-	-	-
HNMDAKOP_01465	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HNMDAKOP_01466	3.39e-254	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HNMDAKOP_01467	9.86e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNMDAKOP_01468	3.3e-180	-	-	-	S	-	-	-	PAS domain
HNMDAKOP_01469	7.77e-66	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HNMDAKOP_01470	2e-22	-	-	-	GM	ko:K13732	ko05100,map05100	ko00000,ko00001	domain, Protein
HNMDAKOP_01471	3.29e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HNMDAKOP_01472	8.7e-123	-	-	-	S	-	-	-	PAS domain
HNMDAKOP_01473	7.57e-304	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HNMDAKOP_01474	3.2e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HNMDAKOP_01475	2.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HNMDAKOP_01476	1.06e-192	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HNMDAKOP_01477	7.76e-233	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
HNMDAKOP_01478	1.17e-99	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HNMDAKOP_01479	1.25e-199	dkgB	-	-	S	-	-	-	reductase
HNMDAKOP_01480	2.42e-201	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HNMDAKOP_01481	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HNMDAKOP_01482	6.57e-97	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HNMDAKOP_01483	4.75e-140	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HNMDAKOP_01484	2.06e-200	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HNMDAKOP_01485	2.39e-189	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HNMDAKOP_01486	4.66e-314	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
HNMDAKOP_01487	7.34e-307	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HNMDAKOP_01488	1.94e-74	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HNMDAKOP_01489	1.45e-97	yybA	-	-	K	-	-	-	Transcriptional regulator
HNMDAKOP_01490	1.5e-112	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HNMDAKOP_01491	5.8e-101	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HNMDAKOP_01492	1.86e-213	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HNMDAKOP_01493	8.97e-204	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HNMDAKOP_01494	1.08e-125	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HNMDAKOP_01495	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HNMDAKOP_01496	3.37e-180	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HNMDAKOP_01497	7.47e-164	-	-	-	S	-	-	-	SNARE associated Golgi protein
HNMDAKOP_01498	9.64e-226	-	-	-	-	-	-	-	-
HNMDAKOP_01499	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HNMDAKOP_01500	3.16e-196	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HNMDAKOP_01501	1.07e-197	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HNMDAKOP_01502	2.53e-139	-	-	-	S	-	-	-	SNARE associated Golgi protein
HNMDAKOP_01503	1.61e-130	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HNMDAKOP_01504	6.46e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HNMDAKOP_01505	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HNMDAKOP_01507	1.79e-294	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HNMDAKOP_01508	1.37e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HNMDAKOP_01509	1.28e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HNMDAKOP_01510	1.99e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HNMDAKOP_01511	1.78e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HNMDAKOP_01512	7.74e-124	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HNMDAKOP_01513	9.63e-95	-	-	-	M	-	-	-	Lysin motif
HNMDAKOP_01514	9.72e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HNMDAKOP_01515	6.48e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HNMDAKOP_01516	1.68e-170	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HNMDAKOP_01517	1.13e-81	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
HNMDAKOP_01518	1.86e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HNMDAKOP_01519	6.45e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HNMDAKOP_01520	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HNMDAKOP_01521	6.89e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HNMDAKOP_01522	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HNMDAKOP_01523	5.24e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HNMDAKOP_01524	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HNMDAKOP_01525	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HNMDAKOP_01526	8.03e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HNMDAKOP_01527	3.39e-183	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMDAKOP_01528	7.99e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HNMDAKOP_01529	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HNMDAKOP_01530	7.6e-306	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HNMDAKOP_01531	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HNMDAKOP_01532	1.95e-220	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HNMDAKOP_01533	2.5e-132	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HNMDAKOP_01534	2.14e-191	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HNMDAKOP_01535	7.17e-313	yagE	-	-	E	-	-	-	amino acid
HNMDAKOP_01536	2.03e-09	-	-	-	-	-	-	-	-
HNMDAKOP_01537	1.28e-153	-	-	-	S	-	-	-	Rib/alpha-like repeat
HNMDAKOP_01538	2.32e-86	-	-	-	S	-	-	-	Domain of unknown function DUF1828
HNMDAKOP_01539	1.94e-86	-	-	-	-	-	-	-	-
HNMDAKOP_01540	5.55e-64	-	-	-	-	-	-	-	-
HNMDAKOP_01541	1.17e-100	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HNMDAKOP_01542	7.34e-159	-	-	-	-	-	-	-	-
HNMDAKOP_01545	1.12e-181	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
HNMDAKOP_01546	1.45e-172	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HNMDAKOP_01548	5.72e-156	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HNMDAKOP_01549	3.65e-227	-	-	-	D	-	-	-	nuclear chromosome segregation
HNMDAKOP_01550	1.49e-170	-	-	-	-	-	-	-	-
HNMDAKOP_01551	8.39e-34	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HNMDAKOP_01552	3.82e-135	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HNMDAKOP_01554	1.08e-63	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HNMDAKOP_01555	2.04e-185	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HNMDAKOP_01556	8.51e-41	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
HNMDAKOP_01557	1.27e-199	-	-	-	S	-	-	-	Acyltransferase family
HNMDAKOP_01558	3.71e-291	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HNMDAKOP_01559	1.42e-113	-	-	-	-	-	-	-	-
HNMDAKOP_01560	1.06e-257	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HNMDAKOP_01561	1.37e-164	-	-	-	M	-	-	-	Glycosyl transferase family 2
HNMDAKOP_01562	4.29e-127	-	-	-	S	-	-	-	glycosyl transferase family 2
HNMDAKOP_01563	8.72e-162	-	-	-	M	-	-	-	Glycosyl transferase family 2
HNMDAKOP_01564	2.19e-163	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HNMDAKOP_01565	2.33e-103	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HNMDAKOP_01566	8.19e-107	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HNMDAKOP_01567	1.23e-149	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
HNMDAKOP_01568	3.26e-177	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HNMDAKOP_01569	2.69e-158	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HNMDAKOP_01570	1.34e-180	epsB	-	-	M	-	-	-	biosynthesis protein
HNMDAKOP_01571	1.66e-209	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HNMDAKOP_01572	9.04e-279	-	-	-	-	-	-	-	-
HNMDAKOP_01573	3e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HNMDAKOP_01574	1.65e-71	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HNMDAKOP_01575	5.74e-37	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HNMDAKOP_01577	1.88e-100	-	-	-	-	-	-	-	-
HNMDAKOP_01578	5.22e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNMDAKOP_01579	1.08e-133	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HNMDAKOP_01580	1.19e-294	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HNMDAKOP_01581	2.71e-273	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HNMDAKOP_01582	2.45e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HNMDAKOP_01583	2.51e-200	-	-	-	-	-	-	-	-
HNMDAKOP_01584	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNMDAKOP_01585	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HNMDAKOP_01586	1.8e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HNMDAKOP_01587	3.1e-223	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HNMDAKOP_01588	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HNMDAKOP_01589	8.68e-136	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HNMDAKOP_01590	1.15e-233	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HNMDAKOP_01591	1.59e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HNMDAKOP_01592	1.23e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HNMDAKOP_01593	3.29e-65	ylbG	-	-	S	-	-	-	UPF0298 protein
HNMDAKOP_01594	6.47e-267	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HNMDAKOP_01595	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HNMDAKOP_01596	9.73e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HNMDAKOP_01597	3.08e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HNMDAKOP_01598	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNMDAKOP_01599	2.99e-205	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HNMDAKOP_01600	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HNMDAKOP_01601	1.15e-147	-	-	-	S	-	-	-	repeat protein
HNMDAKOP_01602	9.12e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HNMDAKOP_01603	2.12e-276	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HNMDAKOP_01604	3.64e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HNMDAKOP_01605	2.28e-271	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HNMDAKOP_01606	2.79e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HNMDAKOP_01607	1.01e-48	-	-	-	-	-	-	-	-
HNMDAKOP_01608	1.22e-131	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HNMDAKOP_01609	1.37e-45	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HNMDAKOP_01610	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HNMDAKOP_01611	1.08e-146	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HNMDAKOP_01612	1.33e-185	ylmH	-	-	S	-	-	-	S4 domain protein
HNMDAKOP_01613	3.9e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HNMDAKOP_01614	2.18e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HNMDAKOP_01615	4.1e-307	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HNMDAKOP_01616	2.12e-308	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HNMDAKOP_01617	1.06e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HNMDAKOP_01618	9.56e-266	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HNMDAKOP_01619	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HNMDAKOP_01620	9e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNMDAKOP_01621	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HNMDAKOP_01622	4.61e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HNMDAKOP_01623	3.34e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HNMDAKOP_01624	7.69e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HNMDAKOP_01625	4.44e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HNMDAKOP_01626	2.36e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HNMDAKOP_01627	3.99e-123	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
HNMDAKOP_01628	6.79e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HNMDAKOP_01629	8.91e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HNMDAKOP_01630	2.07e-140	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HNMDAKOP_01631	2.59e-159	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HNMDAKOP_01632	1.97e-293	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HNMDAKOP_01633	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HNMDAKOP_01634	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HNMDAKOP_01635	3.75e-151	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HNMDAKOP_01636	6.29e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNMDAKOP_01637	2.9e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HNMDAKOP_01638	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HNMDAKOP_01640	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HNMDAKOP_01641	1.7e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HNMDAKOP_01642	2.82e-298	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HNMDAKOP_01643	9.34e-08	-	-	-	-	-	-	-	-
HNMDAKOP_01644	1.43e-105	uspA	-	-	T	-	-	-	universal stress protein
HNMDAKOP_01645	1.07e-283	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HNMDAKOP_01646	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HNMDAKOP_01647	5.54e-69	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HNMDAKOP_01648	3.34e-18	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
HNMDAKOP_01649	3.53e-229	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HNMDAKOP_01650	2.52e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HNMDAKOP_01651	3.48e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HNMDAKOP_01652	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HNMDAKOP_01653	4.95e-219	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HNMDAKOP_01654	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HNMDAKOP_01655	2.19e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNMDAKOP_01656	5.6e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HNMDAKOP_01657	1.75e-35	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNMDAKOP_01658	7.4e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HNMDAKOP_01659	7.5e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HNMDAKOP_01660	1.76e-234	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HNMDAKOP_01661	1.31e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HNMDAKOP_01662	4.43e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HNMDAKOP_01663	1.36e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HNMDAKOP_01664	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HNMDAKOP_01665	1.46e-257	-	-	-	L	-	-	-	Transposase DDE domain
HNMDAKOP_01667	2.75e-69	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Cellulose biosynthesis protein BcsQ
HNMDAKOP_01668	7.18e-55	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HNMDAKOP_01669	5.2e-15	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HNMDAKOP_01670	0.0	-	-	-	-	-	-	-	-
HNMDAKOP_01671	3.66e-275	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HNMDAKOP_01672	1.73e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HNMDAKOP_01673	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HNMDAKOP_01674	8.13e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HNMDAKOP_01675	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HNMDAKOP_01676	2.35e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HNMDAKOP_01677	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HNMDAKOP_01678	5.89e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HNMDAKOP_01679	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HNMDAKOP_01680	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNMDAKOP_01681	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNMDAKOP_01682	7.55e-265	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HNMDAKOP_01683	5.95e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HNMDAKOP_01684	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HNMDAKOP_01685	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HNMDAKOP_01686	2.55e-79	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HNMDAKOP_01687	4.86e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNMDAKOP_01688	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HNMDAKOP_01689	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HNMDAKOP_01690	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HNMDAKOP_01691	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HNMDAKOP_01692	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HNMDAKOP_01693	8.71e-233	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNMDAKOP_01694	3.25e-158	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNMDAKOP_01695	1.63e-205	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HNMDAKOP_01696	7.41e-270	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HNMDAKOP_01697	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HNMDAKOP_01698	1.49e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HNMDAKOP_01699	3.77e-86	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HNMDAKOP_01700	1.88e-312	ynbB	-	-	P	-	-	-	aluminum resistance
HNMDAKOP_01701	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HNMDAKOP_01702	0.0	-	-	-	E	-	-	-	Amino acid permease
HNMDAKOP_01703	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HNMDAKOP_01704	3.13e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HNMDAKOP_01705	1.2e-83	-	-	-	S	-	-	-	Cupredoxin-like domain
HNMDAKOP_01706	2.2e-95	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
HNMDAKOP_01707	4.56e-117	-	-	-	-	-	-	-	-
HNMDAKOP_01708	3.71e-105	-	-	-	-	-	-	-	-
HNMDAKOP_01709	1.92e-88	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HNMDAKOP_01710	7.84e-95	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HNMDAKOP_01711	1.38e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HNMDAKOP_01712	8.82e-58	-	-	-	I	-	-	-	bis(5'-adenosyl)-triphosphatase activity
HNMDAKOP_01713	7.82e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HNMDAKOP_01714	3.36e-164	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HNMDAKOP_01715	1.55e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HNMDAKOP_01716	1.17e-291	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HNMDAKOP_01717	1.34e-160	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HNMDAKOP_01718	6.65e-152	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HNMDAKOP_01719	6.36e-171	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HNMDAKOP_01720	1.35e-201	-	-	-	S	-	-	-	Aldo/keto reductase family
HNMDAKOP_01721	1.39e-82	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HNMDAKOP_01722	2.33e-164	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HNMDAKOP_01723	1.88e-45	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HNMDAKOP_01724	3.81e-50	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMDAKOP_01725	2.28e-188	-	-	-	V	-	-	-	Beta-lactamase
HNMDAKOP_01726	1.26e-247	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HNMDAKOP_01727	4.05e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HNMDAKOP_01728	3.2e-222	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HNMDAKOP_01729	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HNMDAKOP_01730	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HNMDAKOP_01731	1.05e-231	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HNMDAKOP_01732	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HNMDAKOP_01733	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_01734	4.63e-254	-	-	-	S	-	-	-	DUF218 domain
HNMDAKOP_01735	1.89e-142	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HNMDAKOP_01736	2.17e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HNMDAKOP_01737	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HNMDAKOP_01741	2.55e-105	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
HNMDAKOP_01742	4.76e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
HNMDAKOP_01743	9.67e-200	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HNMDAKOP_01744	8.1e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HNMDAKOP_01745	3.78e-40	-	-	-	-	-	-	-	-
HNMDAKOP_01747	4.02e-37	-	-	-	-	-	-	-	-
HNMDAKOP_01748	1.02e-203	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HNMDAKOP_01749	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HNMDAKOP_01751	6.57e-256	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HNMDAKOP_01752	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HNMDAKOP_01753	7.55e-98	ykuL	-	-	S	-	-	-	(CBS) domain
HNMDAKOP_01754	4.16e-24	-	-	-	-	-	-	-	-
HNMDAKOP_01755	5.79e-269	-	-	-	S	-	-	-	Membrane
HNMDAKOP_01756	1.24e-51	-	-	-	-	-	-	-	-
HNMDAKOP_01757	3.25e-05	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HNMDAKOP_01758	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMDAKOP_01759	5.48e-302	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HNMDAKOP_01760	5.16e-50	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMDAKOP_01761	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HNMDAKOP_01762	4.1e-179	pbpX2	-	-	V	-	-	-	Beta-lactamase
HNMDAKOP_01763	2.67e-273	-	-	-	E	-	-	-	Major Facilitator Superfamily
HNMDAKOP_01764	7.08e-52	-	-	-	-	-	-	-	-
HNMDAKOP_01765	1.8e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMDAKOP_01766	2.19e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HNMDAKOP_01767	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
HNMDAKOP_01768	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HNMDAKOP_01770	4.68e-67	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
HNMDAKOP_01771	4.83e-240	-	-	-	-	-	-	-	-
HNMDAKOP_01772	2.57e-158	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HNMDAKOP_01773	1.44e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HNMDAKOP_01774	2.47e-167	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HNMDAKOP_01775	2.5e-257	-	-	-	M	-	-	-	Glycosyl transferases group 1
HNMDAKOP_01776	0.0	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HNMDAKOP_01777	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNMDAKOP_01778	2.06e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HNMDAKOP_01779	0.0	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
HNMDAKOP_01780	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HNMDAKOP_01781	5.29e-285	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HNMDAKOP_01782	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HNMDAKOP_01783	3.29e-170	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HNMDAKOP_01784	5.09e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HNMDAKOP_01786	5.87e-132	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HNMDAKOP_01787	1.35e-143	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HNMDAKOP_01788	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HNMDAKOP_01789	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HNMDAKOP_01790	3.2e-264	camS	-	-	S	-	-	-	sex pheromone
HNMDAKOP_01791	2.23e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNMDAKOP_01792	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HNMDAKOP_01793	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNMDAKOP_01794	5.13e-213	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HNMDAKOP_01796	5.66e-190	-	-	-	S	-	-	-	hydrolase
HNMDAKOP_01797	1.15e-173	-	-	-	M	-	-	-	family 8
HNMDAKOP_01798	1.14e-149	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HNMDAKOP_01799	1.21e-182	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HNMDAKOP_01800	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_01801	2.56e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HNMDAKOP_01802	2.79e-194	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HNMDAKOP_01803	1.01e-307	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HNMDAKOP_01804	1.05e-162	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HNMDAKOP_01805	2.37e-151	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HNMDAKOP_01806	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNMDAKOP_01807	4.57e-166	-	-	-	F	-	-	-	NUDIX domain
HNMDAKOP_01808	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNMDAKOP_01809	8.12e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
HNMDAKOP_01810	3.8e-222	-	-	-	L	ko:K06400	-	ko00000	Recombinase