Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HBBFKNIG_00001	1.44e-53	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HBBFKNIG_00002	6.03e-110	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HBBFKNIG_00003	3.17e-128	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HBBFKNIG_00004	1.2e-09	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HBBFKNIG_00005	1.17e-112	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HBBFKNIG_00006	7.57e-119	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HBBFKNIG_00007	7.59e-94	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HBBFKNIG_00008	9.68e-150	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HBBFKNIG_00009	1.91e-146	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HBBFKNIG_00010	2.25e-112	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HBBFKNIG_00011	1.7e-75	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HBBFKNIG_00012	2.67e-54	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HBBFKNIG_00013	1.58e-28	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HBBFKNIG_00014	4.08e-22	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HBBFKNIG_00015	1.6e-34	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HBBFKNIG_00016	1.79e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HBBFKNIG_00017	2.36e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HBBFKNIG_00018	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HBBFKNIG_00019	1.58e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBBFKNIG_00020	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HBBFKNIG_00021	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HBBFKNIG_00022	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HBBFKNIG_00023	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HBBFKNIG_00024	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HBBFKNIG_00025	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HBBFKNIG_00026	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HBBFKNIG_00027	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HBBFKNIG_00028	3.23e-115	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HBBFKNIG_00029	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HBBFKNIG_00030	3.67e-194	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HBBFKNIG_00031	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HBBFKNIG_00032	1.65e-73	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HBBFKNIG_00033	2.05e-113	ywmA	-	-	-	-	-	-	-
HBBFKNIG_00034	1.07e-43	ywzB	-	-	S	-	-	-	membrane
HBBFKNIG_00035	1.97e-173	ywmB	-	-	S	-	-	-	TATA-box binding
HBBFKNIG_00036	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBBFKNIG_00037	2.8e-233	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HBBFKNIG_00038	1.89e-157	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HBBFKNIG_00039	1.02e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HBBFKNIG_00041	5.24e-186	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBBFKNIG_00042	1.08e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBBFKNIG_00043	1.16e-126	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HBBFKNIG_00044	6.49e-109	ywmF	-	-	S	-	-	-	Peptidase M50
HBBFKNIG_00045	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
HBBFKNIG_00046	1.89e-25	-	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HBBFKNIG_00047	1.66e-67	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HBBFKNIG_00048	1.85e-82	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HBBFKNIG_00049	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HBBFKNIG_00050	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00051	1.76e-146	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HBBFKNIG_00052	1.24e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HBBFKNIG_00053	4.85e-184	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HBBFKNIG_00054	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBBFKNIG_00055	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HBBFKNIG_00056	9.51e-234	-	-	-	M	-	-	-	NeuB family
HBBFKNIG_00057	1.79e-21	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HBBFKNIG_00058	1.74e-113	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HBBFKNIG_00059	2.51e-159	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HBBFKNIG_00060	6.63e-95	ywnJ	-	-	S	-	-	-	VanZ like family
HBBFKNIG_00061	4.95e-134	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HBBFKNIG_00062	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HBBFKNIG_00063	1.6e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HBBFKNIG_00065	3.55e-101	-	-	-	-	-	-	-	-
HBBFKNIG_00066	1.48e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
HBBFKNIG_00067	8.92e-306	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HBBFKNIG_00068	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HBBFKNIG_00069	2.5e-296	ywoF	-	-	P	-	-	-	Right handed beta helix region
HBBFKNIG_00070	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_00071	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
HBBFKNIG_00072	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HBBFKNIG_00073	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HBBFKNIG_00074	1.02e-171	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HBBFKNIG_00075	1.37e-180	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HBBFKNIG_00076	7.42e-255	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HBBFKNIG_00077	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HBBFKNIG_00078	9.32e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HBBFKNIG_00079	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
HBBFKNIG_00080	4.13e-222	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HBBFKNIG_00081	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HBBFKNIG_00082	1.76e-108	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HBBFKNIG_00083	2.95e-87	ywpF	-	-	S	-	-	-	YwpF-like protein
HBBFKNIG_00084	5.26e-88	ywpG	-	-	-	-	-	-	-
HBBFKNIG_00085	1.21e-75	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HBBFKNIG_00086	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HBBFKNIG_00087	3.06e-201	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HBBFKNIG_00088	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HBBFKNIG_00089	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HBBFKNIG_00090	7.28e-25	-	-	-	-	-	-	-	-
HBBFKNIG_00091	2.17e-162	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HBBFKNIG_00092	2.02e-157	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HBBFKNIG_00093	1.75e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HBBFKNIG_00094	2.69e-312	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HBBFKNIG_00095	4.51e-191	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HBBFKNIG_00097	2.17e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HBBFKNIG_00098	3.64e-264	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
HBBFKNIG_00099	1.77e-26	-	-	-	-	-	-	-	-
HBBFKNIG_00100	1.3e-23	-	-	-	-	-	-	-	-
HBBFKNIG_00101	3.51e-98	ywqJ	-	-	S	-	-	-	Pre-toxin TG
HBBFKNIG_00103	3.19e-152	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HBBFKNIG_00104	8.62e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HBBFKNIG_00105	3.73e-131	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HBBFKNIG_00106	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HBBFKNIG_00107	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HBBFKNIG_00108	1.09e-68	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
HBBFKNIG_00109	5.08e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBBFKNIG_00110	7.25e-18	-	-	-	-	-	-	-	-
HBBFKNIG_00111	1.47e-265	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HBBFKNIG_00112	1.59e-175	cotB	-	-	-	ko:K06325	-	ko00000	-
HBBFKNIG_00113	3.04e-162	ywrJ	-	-	-	-	-	-	-
HBBFKNIG_00114	1.32e-278	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBBFKNIG_00115	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
HBBFKNIG_00116	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HBBFKNIG_00117	3.71e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HBBFKNIG_00118	3.43e-123	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HBBFKNIG_00119	2.17e-62	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
HBBFKNIG_00120	3.97e-119	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HBBFKNIG_00121	1.28e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HBBFKNIG_00122	2.75e-202	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HBBFKNIG_00123	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HBBFKNIG_00124	1.09e-82	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HBBFKNIG_00125	6.18e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBBFKNIG_00126	7.36e-225	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HBBFKNIG_00127	2.08e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HBBFKNIG_00128	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HBBFKNIG_00129	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HBBFKNIG_00130	2.29e-29	ywtC	-	-	-	-	-	-	-
HBBFKNIG_00131	1.53e-301	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HBBFKNIG_00132	8.45e-204	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HBBFKNIG_00133	3.19e-181	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00134	9.1e-315	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBBFKNIG_00135	2.52e-263	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HBBFKNIG_00136	4.24e-248	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HBBFKNIG_00137	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HBBFKNIG_00138	4.53e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HBBFKNIG_00139	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBBFKNIG_00140	1.42e-235	tarL	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HBBFKNIG_00141	6.69e-110	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	M	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HBBFKNIG_00142	5.68e-186	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HBBFKNIG_00143	2.07e-134	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HBBFKNIG_00144	3.84e-117	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HBBFKNIG_00145	9.68e-111	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HBBFKNIG_00146	3.25e-74	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HBBFKNIG_00147	1.79e-166	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HBBFKNIG_00148	5.87e-134	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HBBFKNIG_00149	1.59e-101	-	-	-	-	-	-	-	-
HBBFKNIG_00150	6.73e-165	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HBBFKNIG_00151	7.7e-182	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HBBFKNIG_00152	1.67e-168	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HBBFKNIG_00153	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HBBFKNIG_00154	2.74e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HBBFKNIG_00156	6.85e-118	-	-	-	M	-	-	-	Glycosyl transferases group 1
HBBFKNIG_00157	4.13e-103	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HBBFKNIG_00158	8.63e-274	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HBBFKNIG_00159	1.16e-211	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HBBFKNIG_00160	9.07e-16	-	-	-	-	-	-	-	-
HBBFKNIG_00161	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
HBBFKNIG_00162	1.84e-264	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HBBFKNIG_00163	9e-109	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HBBFKNIG_00164	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HBBFKNIG_00165	3.44e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBBFKNIG_00166	1.15e-278	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HBBFKNIG_00167	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HBBFKNIG_00168	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HBBFKNIG_00169	8.23e-147	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HBBFKNIG_00170	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HBBFKNIG_00171	3.96e-295	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HBBFKNIG_00172	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HBBFKNIG_00173	8.05e-225	yvhJ	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00174	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HBBFKNIG_00175	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HBBFKNIG_00176	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBBFKNIG_00177	1.77e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_00178	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HBBFKNIG_00179	1.04e-60	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HBBFKNIG_00180	8.82e-160	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HBBFKNIG_00181	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
HBBFKNIG_00182	5.05e-52	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HBBFKNIG_00183	7.06e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
HBBFKNIG_00184	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HBBFKNIG_00185	1.55e-196	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HBBFKNIG_00186	1.7e-92	yviE	-	-	-	-	-	-	-
HBBFKNIG_00187	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HBBFKNIG_00188	2.58e-41	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HBBFKNIG_00189	1.43e-124	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBBFKNIG_00190	1.1e-76	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
HBBFKNIG_00191	1.67e-316	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HBBFKNIG_00192	1.48e-90	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HBBFKNIG_00193	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HBBFKNIG_00194	9.14e-88	-	-	-	-	-	-	-	-
HBBFKNIG_00195	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HBBFKNIG_00196	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HBBFKNIG_00197	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HBBFKNIG_00198	1.86e-184	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBBFKNIG_00199	1.87e-74	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HBBFKNIG_00200	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HBBFKNIG_00201	5.45e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HBBFKNIG_00202	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HBBFKNIG_00203	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
HBBFKNIG_00204	1.29e-279	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBBFKNIG_00205	7.12e-294	yvkA	-	-	P	-	-	-	-transporter
HBBFKNIG_00206	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00207	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HBBFKNIG_00208	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_00209	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HBBFKNIG_00210	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HBBFKNIG_00211	6.4e-149	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBBFKNIG_00212	2.25e-45	yvkN	-	-	-	-	-	-	-
HBBFKNIG_00213	8.09e-65	yvlA	-	-	-	-	-	-	-
HBBFKNIG_00214	9.59e-220	yvlB	-	-	S	-	-	-	Putative adhesin
HBBFKNIG_00215	6.11e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HBBFKNIG_00216	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HBBFKNIG_00217	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HBBFKNIG_00218	3.53e-170	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HBBFKNIG_00219	3.66e-167	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HBBFKNIG_00220	8.41e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HBBFKNIG_00221	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HBBFKNIG_00222	1.29e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HBBFKNIG_00223	5.65e-206	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
HBBFKNIG_00224	3.56e-152	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HBBFKNIG_00225	1.07e-120	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HBBFKNIG_00226	8.06e-156	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
HBBFKNIG_00227	6.12e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HBBFKNIG_00228	4.18e-282	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HBBFKNIG_00229	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HBBFKNIG_00230	8.61e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HBBFKNIG_00231	2.87e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HBBFKNIG_00232	6.37e-144	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HBBFKNIG_00233	1.32e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HBBFKNIG_00234	5.63e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HBBFKNIG_00235	6.62e-140	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HBBFKNIG_00236	4.97e-115	-	-	-	-	-	-	-	-
HBBFKNIG_00237	7.45e-258	-	-	-	-	-	-	-	-
HBBFKNIG_00239	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HBBFKNIG_00240	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HBBFKNIG_00241	7.05e-188	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HBBFKNIG_00242	1.18e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HBBFKNIG_00243	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HBBFKNIG_00244	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HBBFKNIG_00245	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HBBFKNIG_00246	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HBBFKNIG_00247	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HBBFKNIG_00248	9.36e-182	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HBBFKNIG_00249	1.37e-45	-	-	-	-	-	-	-	-
HBBFKNIG_00250	3.16e-170	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_00251	1.13e-250	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HBBFKNIG_00252	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_00253	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HBBFKNIG_00254	2.59e-231	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBBFKNIG_00255	3.73e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HBBFKNIG_00256	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HBBFKNIG_00257	6.45e-70	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HBBFKNIG_00258	2.19e-136	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HBBFKNIG_00259	1.32e-222	yvdE	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00260	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
HBBFKNIG_00261	2.83e-300	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HBBFKNIG_00262	1.01e-309	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HBBFKNIG_00263	6.56e-188	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HBBFKNIG_00264	2.5e-200	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HBBFKNIG_00265	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
HBBFKNIG_00266	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HBBFKNIG_00267	2.08e-144	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HBBFKNIG_00268	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HBBFKNIG_00272	4.88e-47	-	-	-	-	-	-	-	-
HBBFKNIG_00273	1.51e-113	sdpB	-	-	S	-	-	-	Vitamin K-dependent gamma-carboxylase
HBBFKNIG_00274	4.27e-95	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HBBFKNIG_00275	1.3e-120	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
HBBFKNIG_00276	4.21e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HBBFKNIG_00277	7.37e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HBBFKNIG_00278	2.75e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00279	0.0	ybeC	-	-	E	-	-	-	amino acid
HBBFKNIG_00280	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HBBFKNIG_00281	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HBBFKNIG_00282	1.22e-90	-	-	-	-	-	-	-	-
HBBFKNIG_00283	9.57e-89	pbpE	-	-	V	-	-	-	Beta-lactamase
HBBFKNIG_00284	7.05e-218	pbpE	-	-	V	-	-	-	Beta-lactamase
HBBFKNIG_00285	1.1e-156	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HBBFKNIG_00286	4.48e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HBBFKNIG_00287	8.97e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HBBFKNIG_00289	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HBBFKNIG_00290	4.17e-97	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HBBFKNIG_00291	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HBBFKNIG_00292	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HBBFKNIG_00293	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HBBFKNIG_00294	5.25e-280	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HBBFKNIG_00295	1.46e-200	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HBBFKNIG_00296	2.4e-276	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HBBFKNIG_00297	2.08e-263	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HBBFKNIG_00298	1.17e-246	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HBBFKNIG_00299	1.1e-258	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HBBFKNIG_00300	1.53e-242	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HBBFKNIG_00301	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBBFKNIG_00302	9.14e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HBBFKNIG_00303	7.65e-79	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HBBFKNIG_00304	8.34e-276	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HBBFKNIG_00305	1.99e-236	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HBBFKNIG_00306	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
HBBFKNIG_00307	4.75e-304	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HBBFKNIG_00308	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HBBFKNIG_00309	6.85e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HBBFKNIG_00310	8.12e-236	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_00311	6.57e-292	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HBBFKNIG_00312	2.15e-300	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HBBFKNIG_00313	7.72e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HBBFKNIG_00314	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HBBFKNIG_00315	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HBBFKNIG_00316	3.8e-259	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
HBBFKNIG_00317	8.47e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
HBBFKNIG_00318	3.16e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HBBFKNIG_00319	1.68e-169	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HBBFKNIG_00320	3.25e-253	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_00321	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBBFKNIG_00322	1.76e-172	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HBBFKNIG_00323	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HBBFKNIG_00324	5.65e-170	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HBBFKNIG_00325	1.22e-248	-	-	-	S	-	-	-	Glycosyl hydrolase
HBBFKNIG_00326	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HBBFKNIG_00327	2.27e-197	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HBBFKNIG_00328	8.12e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00329	8.53e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBBFKNIG_00330	4.32e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HBBFKNIG_00331	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBBFKNIG_00332	2.42e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HBBFKNIG_00333	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HBBFKNIG_00334	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HBBFKNIG_00335	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HBBFKNIG_00336	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HBBFKNIG_00337	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HBBFKNIG_00338	8.59e-209	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HBBFKNIG_00339	1.58e-274	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	UDP binding domain
HBBFKNIG_00340	3.75e-234	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HBBFKNIG_00341	4.28e-188	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
HBBFKNIG_00342	4.91e-198	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HBBFKNIG_00343	7.3e-144	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
HBBFKNIG_00344	8.28e-157	-	-	-	C	-	-	-	WbqC-like protein family
HBBFKNIG_00345	3.24e-148	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HBBFKNIG_00346	1.25e-192	-	-	-	-	-	-	-	-
HBBFKNIG_00347	5.68e-221	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HBBFKNIG_00348	8.03e-105	yvbK	-	-	K	-	-	-	acetyltransferase
HBBFKNIG_00349	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HBBFKNIG_00350	2.55e-153	yvbI	-	-	M	-	-	-	Membrane
HBBFKNIG_00351	8.48e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
HBBFKNIG_00352	2.28e-134	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HBBFKNIG_00353	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HBBFKNIG_00354	1.31e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HBBFKNIG_00355	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HBBFKNIG_00356	1.49e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HBBFKNIG_00357	1.6e-135	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HBBFKNIG_00358	6.63e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HBBFKNIG_00359	1.73e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HBBFKNIG_00360	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HBBFKNIG_00361	5.58e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HBBFKNIG_00362	7.45e-128	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HBBFKNIG_00363	3.7e-44	-	-	-	O	ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HBBFKNIG_00365	6.21e-29	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
HBBFKNIG_00367	1.83e-70	yvaP	-	-	K	-	-	-	transcriptional
HBBFKNIG_00368	1.1e-88	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HBBFKNIG_00369	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HBBFKNIG_00370	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
HBBFKNIG_00371	8.15e-194	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
HBBFKNIG_00372	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HBBFKNIG_00373	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HBBFKNIG_00374	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HBBFKNIG_00375	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HBBFKNIG_00377	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBBFKNIG_00378	1.17e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HBBFKNIG_00379	3.52e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HBBFKNIG_00380	2.02e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HBBFKNIG_00381	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HBBFKNIG_00382	3.59e-154	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBBFKNIG_00383	5.38e-250	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HBBFKNIG_00384	5.67e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HBBFKNIG_00385	3.66e-41	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
HBBFKNIG_00386	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HBBFKNIG_00387	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HBBFKNIG_00388	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
HBBFKNIG_00389	1.15e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HBBFKNIG_00390	2.34e-139	yvgT	-	-	S	-	-	-	membrane
HBBFKNIG_00392	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HBBFKNIG_00393	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HBBFKNIG_00394	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HBBFKNIG_00395	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HBBFKNIG_00396	7.97e-113	yvgO	-	-	-	-	-	-	-
HBBFKNIG_00397	6.19e-201	yvgN	-	-	S	-	-	-	reductase
HBBFKNIG_00398	1.74e-153	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HBBFKNIG_00399	2.11e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HBBFKNIG_00400	2.09e-213	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HBBFKNIG_00401	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HBBFKNIG_00402	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HBBFKNIG_00403	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HBBFKNIG_00404	1.34e-313	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HBBFKNIG_00405	6.32e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBBFKNIG_00406	7e-236	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_00407	1.12e-224	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_00408	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HBBFKNIG_00409	9.86e-229	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
HBBFKNIG_00410	4.64e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_00411	5.57e-271	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HBBFKNIG_00412	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HBBFKNIG_00413	1.08e-290	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HBBFKNIG_00414	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
HBBFKNIG_00415	2.35e-126	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HBBFKNIG_00416	7.2e-32	-	-	-	-	-	-	-	-
HBBFKNIG_00417	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_00418	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HBBFKNIG_00419	3.64e-217	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HBBFKNIG_00420	2.12e-181	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBBFKNIG_00421	1.41e-216	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HBBFKNIG_00422	2.7e-236	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_00423	1.22e-307	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HBBFKNIG_00424	5.32e-129	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HBBFKNIG_00425	1.13e-288	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_00426	1.51e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HBBFKNIG_00427	2.44e-143	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HBBFKNIG_00428	1.72e-173	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HBBFKNIG_00429	1.09e-163	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HBBFKNIG_00430	4.06e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_00431	5.43e-140	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBBFKNIG_00432	1.97e-239	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HBBFKNIG_00433	7.95e-251	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HBBFKNIG_00434	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HBBFKNIG_00435	2.6e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HBBFKNIG_00436	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HBBFKNIG_00437	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00438	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_00439	1.83e-163	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_00440	5.32e-303	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBBFKNIG_00441	2.15e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
HBBFKNIG_00442	4.49e-196	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBBFKNIG_00443	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HBBFKNIG_00444	2.86e-87	-	-	-	S	-	-	-	YusW-like protein
HBBFKNIG_00445	1.06e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HBBFKNIG_00446	3.66e-64	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HBBFKNIG_00447	2.7e-200	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
HBBFKNIG_00448	9.56e-136	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBBFKNIG_00449	1.19e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
HBBFKNIG_00450	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HBBFKNIG_00451	2.21e-96	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HBBFKNIG_00452	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
HBBFKNIG_00453	2.23e-54	-	-	-	-	-	-	-	-
HBBFKNIG_00454	2e-210	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HBBFKNIG_00455	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
HBBFKNIG_00456	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HBBFKNIG_00457	7.74e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HBBFKNIG_00458	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HBBFKNIG_00459	4.13e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HBBFKNIG_00460	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HBBFKNIG_00461	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HBBFKNIG_00462	7.62e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HBBFKNIG_00463	2e-73	yusE	-	-	CO	-	-	-	Thioredoxin
HBBFKNIG_00464	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HBBFKNIG_00465	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBBFKNIG_00466	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HBBFKNIG_00467	4.82e-188	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HBBFKNIG_00468	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBBFKNIG_00469	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HBBFKNIG_00470	1.06e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HBBFKNIG_00471	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBBFKNIG_00472	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HBBFKNIG_00473	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HBBFKNIG_00474	5.06e-86	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBBFKNIG_00475	3.35e-56	-	-	-	-	-	-	-	-
HBBFKNIG_00477	6.19e-263	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HBBFKNIG_00478	1.36e-84	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HBBFKNIG_00479	5.27e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HBBFKNIG_00480	8.81e-302	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HBBFKNIG_00481	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBBFKNIG_00482	2.65e-214	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HBBFKNIG_00483	2.25e-207	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HBBFKNIG_00484	8.71e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HBBFKNIG_00485	2.83e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBBFKNIG_00486	3.63e-215	bsn	-	-	L	-	-	-	Ribonuclease
HBBFKNIG_00487	6.56e-292	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HBBFKNIG_00488	1.58e-301	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HBBFKNIG_00490	1.33e-229	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HBBFKNIG_00491	9.85e-140	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HBBFKNIG_00492	3.22e-183	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HBBFKNIG_00493	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HBBFKNIG_00494	5.71e-121	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HBBFKNIG_00495	1.26e-73	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HBBFKNIG_00496	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HBBFKNIG_00497	3.18e-283	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HBBFKNIG_00498	1.28e-294	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
HBBFKNIG_00499	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HBBFKNIG_00500	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HBBFKNIG_00501	6.96e-76	yunG	-	-	-	-	-	-	-
HBBFKNIG_00502	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HBBFKNIG_00503	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HBBFKNIG_00504	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HBBFKNIG_00505	3.28e-63	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
HBBFKNIG_00506	3.49e-169	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HBBFKNIG_00507	4.42e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HBBFKNIG_00508	5.56e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBBFKNIG_00509	7.77e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HBBFKNIG_00510	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_00511	2.29e-97	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HBBFKNIG_00512	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HBBFKNIG_00513	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HBBFKNIG_00514	1.27e-252	yutH	-	-	S	-	-	-	Spore coat protein
HBBFKNIG_00515	2.37e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HBBFKNIG_00516	2.4e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HBBFKNIG_00517	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HBBFKNIG_00518	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HBBFKNIG_00519	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HBBFKNIG_00520	4.48e-73	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_00521	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HBBFKNIG_00522	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HBBFKNIG_00523	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBBFKNIG_00524	6.46e-207	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HBBFKNIG_00525	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HBBFKNIG_00526	9.39e-114	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBBFKNIG_00527	4.04e-149	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
HBBFKNIG_00528	2.61e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HBBFKNIG_00530	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HBBFKNIG_00531	9.81e-300	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HBBFKNIG_00532	5.41e-44	yuiB	-	-	S	-	-	-	Putative membrane protein
HBBFKNIG_00533	2.69e-150	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_00534	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HBBFKNIG_00535	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HBBFKNIG_00536	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HBBFKNIG_00537	1.13e-122	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HBBFKNIG_00538	1.13e-155	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HBBFKNIG_00539	4.96e-210	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HBBFKNIG_00540	9.66e-177	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBBFKNIG_00541	7.03e-289	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HBBFKNIG_00542	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HBBFKNIG_00543	1.01e-224	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HBBFKNIG_00544	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBBFKNIG_00545	4.08e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HBBFKNIG_00546	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HBBFKNIG_00547	4.02e-262	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HBBFKNIG_00548	4.91e-291	yukF	-	-	QT	-	-	-	Transcriptional regulator
HBBFKNIG_00549	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HBBFKNIG_00550	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HBBFKNIG_00551	3.65e-270	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HBBFKNIG_00552	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HBBFKNIG_00553	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HBBFKNIG_00554	4.37e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HBBFKNIG_00555	2.48e-170	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBBFKNIG_00556	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HBBFKNIG_00557	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HBBFKNIG_00558	8.02e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
HBBFKNIG_00559	2.73e-244	yueF	-	-	S	-	-	-	transporter activity
HBBFKNIG_00560	1.19e-41	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HBBFKNIG_00561	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
HBBFKNIG_00562	1.04e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HBBFKNIG_00563	3.27e-134	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HBBFKNIG_00564	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HBBFKNIG_00565	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HBBFKNIG_00566	9.77e-08	yuzC	-	-	-	-	-	-	-
HBBFKNIG_00567	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
HBBFKNIG_00568	2.19e-163	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
HBBFKNIG_00570	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_00571	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBBFKNIG_00572	1.58e-82	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HBBFKNIG_00573	8.49e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HBBFKNIG_00574	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HBBFKNIG_00575	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HBBFKNIG_00576	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HBBFKNIG_00577	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HBBFKNIG_00578	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HBBFKNIG_00579	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HBBFKNIG_00580	1.73e-22	-	-	-	-	-	-	-	-
HBBFKNIG_00581	3.25e-308	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
HBBFKNIG_00582	4.9e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HBBFKNIG_00583	4.31e-235	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HBBFKNIG_00584	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_00585	1.28e-253	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HBBFKNIG_00586	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HBBFKNIG_00587	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HBBFKNIG_00588	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HBBFKNIG_00589	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_00590	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HBBFKNIG_00591	1.26e-241	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HBBFKNIG_00593	6.98e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HBBFKNIG_00594	8.69e-92	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HBBFKNIG_00595	1.76e-295	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_00596	4.04e-287	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HBBFKNIG_00597	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HBBFKNIG_00598	1.71e-201	yugF	-	-	I	-	-	-	Hydrolase
HBBFKNIG_00599	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00600	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HBBFKNIG_00601	1.43e-82	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HBBFKNIG_00602	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HBBFKNIG_00603	4.72e-286	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HBBFKNIG_00604	4.57e-290	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HBBFKNIG_00605	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HBBFKNIG_00607	1.72e-94	yugN	-	-	S	-	-	-	YugN-like family
HBBFKNIG_00608	2.92e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HBBFKNIG_00609	1.01e-68	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HBBFKNIG_00610	1.58e-50	-	-	-	-	-	-	-	-
HBBFKNIG_00611	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HBBFKNIG_00612	6.92e-298	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HBBFKNIG_00613	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HBBFKNIG_00614	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HBBFKNIG_00615	2.9e-47	-	-	-	-	-	-	-	-
HBBFKNIG_00616	2.51e-180	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HBBFKNIG_00617	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBBFKNIG_00618	6.7e-290	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBBFKNIG_00619	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBBFKNIG_00620	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBBFKNIG_00621	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
HBBFKNIG_00622	8.22e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HBBFKNIG_00623	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HBBFKNIG_00624	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HBBFKNIG_00625	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HBBFKNIG_00626	4.15e-232	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HBBFKNIG_00627	4.06e-251	yubA	-	-	S	-	-	-	transporter activity
HBBFKNIG_00628	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HBBFKNIG_00630	3.25e-112	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
HBBFKNIG_00631	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HBBFKNIG_00632	4.49e-197	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBBFKNIG_00633	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
HBBFKNIG_00634	8.78e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
HBBFKNIG_00635	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HBBFKNIG_00636	5.83e-118	yuaB	-	-	-	-	-	-	-
HBBFKNIG_00637	1.38e-120	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HBBFKNIG_00638	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HBBFKNIG_00639	2.88e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HBBFKNIG_00640	1.66e-136	yuaD	-	-	-	-	-	-	-
HBBFKNIG_00641	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
HBBFKNIG_00642	5.63e-108	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HBBFKNIG_00643	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HBBFKNIG_00644	4.9e-63	-	-	-	M	-	-	-	FR47-like protein
HBBFKNIG_00645	1e-33	-	-	-	M	-	-	-	FR47-like protein
HBBFKNIG_00646	3.58e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HBBFKNIG_00648	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBBFKNIG_00670	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HBBFKNIG_00671	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HBBFKNIG_00672	1.58e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
HBBFKNIG_00673	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HBBFKNIG_00674	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HBBFKNIG_00675	1.97e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HBBFKNIG_00676	1.5e-259	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
HBBFKNIG_00677	5.85e-275	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
HBBFKNIG_00678	2.71e-260	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
HBBFKNIG_00680	2.91e-297	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
HBBFKNIG_00681	6.1e-228	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
HBBFKNIG_00682	2.77e-308	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HBBFKNIG_00683	1.91e-193	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HBBFKNIG_00684	8.68e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HBBFKNIG_00685	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HBBFKNIG_00686	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HBBFKNIG_00687	9.85e-197	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HBBFKNIG_00688	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HBBFKNIG_00689	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HBBFKNIG_00690	9.63e-271	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HBBFKNIG_00691	1.08e-216	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HBBFKNIG_00692	8.01e-175	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HBBFKNIG_00693	9.07e-297	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HBBFKNIG_00694	2.53e-189	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HBBFKNIG_00695	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HBBFKNIG_00696	1.64e-238	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HBBFKNIG_00697	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HBBFKNIG_00698	2.05e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HBBFKNIG_00699	1.27e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HBBFKNIG_00700	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HBBFKNIG_00701	1.6e-93	ytkA	-	-	S	-	-	-	YtkA-like
HBBFKNIG_00703	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HBBFKNIG_00704	1.52e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HBBFKNIG_00705	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HBBFKNIG_00706	5.39e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HBBFKNIG_00707	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HBBFKNIG_00708	2.66e-240	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HBBFKNIG_00709	6.67e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HBBFKNIG_00710	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HBBFKNIG_00711	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HBBFKNIG_00712	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HBBFKNIG_00713	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HBBFKNIG_00714	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HBBFKNIG_00715	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBBFKNIG_00716	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HBBFKNIG_00717	4.61e-274	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HBBFKNIG_00718	2.75e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HBBFKNIG_00719	9.56e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HBBFKNIG_00720	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HBBFKNIG_00722	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HBBFKNIG_00723	1.03e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_00724	4.18e-216	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HBBFKNIG_00725	7.89e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HBBFKNIG_00726	1.02e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_00727	9.81e-297	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HBBFKNIG_00728	2.23e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_00729	3.06e-237	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HBBFKNIG_00730	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_00731	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HBBFKNIG_00732	1.08e-75	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HBBFKNIG_00733	1.41e-267	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HBBFKNIG_00734	1.49e-180	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HBBFKNIG_00735	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HBBFKNIG_00736	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HBBFKNIG_00737	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
HBBFKNIG_00738	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HBBFKNIG_00739	5.16e-184	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HBBFKNIG_00740	1.66e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBBFKNIG_00741	8.26e-309	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HBBFKNIG_00742	6.21e-242	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_00743	9.68e-221	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
HBBFKNIG_00744	7.82e-180	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HBBFKNIG_00745	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HBBFKNIG_00746	2.58e-275	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HBBFKNIG_00747	1.55e-158	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HBBFKNIG_00748	1.78e-241	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HBBFKNIG_00749	1.1e-279	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HBBFKNIG_00750	2.21e-178	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
HBBFKNIG_00751	1.02e-191	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HBBFKNIG_00752	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HBBFKNIG_00753	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00754	1.87e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HBBFKNIG_00755	3.52e-280	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HBBFKNIG_00756	2.76e-93	yteS	-	-	G	-	-	-	transport
HBBFKNIG_00757	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HBBFKNIG_00758	9.36e-151	yteU	-	-	S	-	-	-	Integral membrane protein
HBBFKNIG_00759	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HBBFKNIG_00760	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HBBFKNIG_00761	8.15e-293	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HBBFKNIG_00762	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBBFKNIG_00763	1.68e-166	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HBBFKNIG_00764	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HBBFKNIG_00765	3.14e-165	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HBBFKNIG_00766	7.09e-255	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HBBFKNIG_00767	1.73e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HBBFKNIG_00768	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HBBFKNIG_00769	1.22e-220	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HBBFKNIG_00770	3.53e-129	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HBBFKNIG_00771	1.41e-211	ytlQ	-	-	-	-	-	-	-
HBBFKNIG_00772	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HBBFKNIG_00773	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HBBFKNIG_00774	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
HBBFKNIG_00775	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
HBBFKNIG_00776	3.07e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HBBFKNIG_00777	1.06e-190	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HBBFKNIG_00778	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HBBFKNIG_00779	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
HBBFKNIG_00780	1.51e-260	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HBBFKNIG_00781	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HBBFKNIG_00782	4.51e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HBBFKNIG_00783	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HBBFKNIG_00784	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HBBFKNIG_00785	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HBBFKNIG_00786	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HBBFKNIG_00787	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HBBFKNIG_00788	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HBBFKNIG_00789	1.57e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HBBFKNIG_00790	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HBBFKNIG_00791	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HBBFKNIG_00792	6.84e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HBBFKNIG_00793	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HBBFKNIG_00794	3.09e-291	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HBBFKNIG_00795	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HBBFKNIG_00796	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HBBFKNIG_00797	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HBBFKNIG_00798	2.16e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBBFKNIG_00800	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HBBFKNIG_00801	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HBBFKNIG_00802	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HBBFKNIG_00803	6.92e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00804	1.77e-196	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HBBFKNIG_00805	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HBBFKNIG_00806	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HBBFKNIG_00807	3.9e-266	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HBBFKNIG_00808	5.14e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBBFKNIG_00809	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HBBFKNIG_00810	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HBBFKNIG_00811	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HBBFKNIG_00812	2.4e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBBFKNIG_00813	1.38e-229	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HBBFKNIG_00814	1.37e-110	yteJ	-	-	S	-	-	-	RDD family
HBBFKNIG_00815	8.34e-149	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HBBFKNIG_00816	4.34e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HBBFKNIG_00817	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HBBFKNIG_00818	1.79e-222	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HBBFKNIG_00819	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBBFKNIG_00820	2.72e-113	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HBBFKNIG_00821	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HBBFKNIG_00822	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HBBFKNIG_00824	8.04e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBBFKNIG_00825	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HBBFKNIG_00826	1.13e-219	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
HBBFKNIG_00827	3.42e-129	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HBBFKNIG_00828	2.61e-194	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HBBFKNIG_00829	2.98e-185	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HBBFKNIG_00830	6.75e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBBFKNIG_00831	3.75e-152	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBBFKNIG_00832	2.21e-181	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HBBFKNIG_00833	5.91e-235	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBBFKNIG_00834	6.34e-56	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
HBBFKNIG_00835	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBBFKNIG_00836	2.45e-157	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
HBBFKNIG_00837	3.56e-298	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HBBFKNIG_00838	2.14e-204	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HBBFKNIG_00839	4.61e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HBBFKNIG_00840	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
HBBFKNIG_00841	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HBBFKNIG_00842	1.15e-39	-	-	-	-	-	-	-	-
HBBFKNIG_00843	5.12e-112	ytrI	-	-	-	-	-	-	-
HBBFKNIG_00844	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HBBFKNIG_00845	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HBBFKNIG_00846	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HBBFKNIG_00847	2.17e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HBBFKNIG_00848	5.68e-233	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HBBFKNIG_00849	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HBBFKNIG_00850	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HBBFKNIG_00851	1.91e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HBBFKNIG_00852	1.58e-244	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HBBFKNIG_00853	9.38e-95	ytwI	-	-	S	-	-	-	membrane
HBBFKNIG_00854	1.36e-266	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HBBFKNIG_00855	9.27e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HBBFKNIG_00856	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HBBFKNIG_00857	3.27e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_00858	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HBBFKNIG_00859	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBBFKNIG_00860	3.88e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HBBFKNIG_00861	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HBBFKNIG_00862	4.67e-125	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBBFKNIG_00863	1.85e-204	ytbE	-	-	S	-	-	-	reductase
HBBFKNIG_00864	4.46e-259	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HBBFKNIG_00865	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_00866	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HBBFKNIG_00867	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HBBFKNIG_00868	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HBBFKNIG_00869	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HBBFKNIG_00870	1.22e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HBBFKNIG_00871	1.22e-137	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HBBFKNIG_00872	1.41e-204	ytxC	-	-	S	-	-	-	YtxC-like family
HBBFKNIG_00873	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HBBFKNIG_00874	1.2e-190	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HBBFKNIG_00875	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_00876	3.39e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HBBFKNIG_00877	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HBBFKNIG_00878	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HBBFKNIG_00880	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HBBFKNIG_00881	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HBBFKNIG_00882	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HBBFKNIG_00883	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
HBBFKNIG_00884	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HBBFKNIG_00885	1.77e-261	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HBBFKNIG_00886	4.16e-234	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HBBFKNIG_00887	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HBBFKNIG_00888	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HBBFKNIG_00889	6.93e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HBBFKNIG_00890	2.88e-185	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HBBFKNIG_00891	2.93e-279	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HBBFKNIG_00892	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HBBFKNIG_00893	3.22e-217	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HBBFKNIG_00894	4.28e-190	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HBBFKNIG_00895	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HBBFKNIG_00896	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HBBFKNIG_00897	5.93e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
HBBFKNIG_00898	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HBBFKNIG_00899	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HBBFKNIG_00900	7.2e-260	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HBBFKNIG_00901	7.27e-42	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HBBFKNIG_00902	2.57e-170	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBBFKNIG_00903	5.18e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HBBFKNIG_00904	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HBBFKNIG_00905	2.76e-218	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBBFKNIG_00906	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HBBFKNIG_00907	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HBBFKNIG_00908	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HBBFKNIG_00909	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HBBFKNIG_00910	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HBBFKNIG_00911	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HBBFKNIG_00912	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_00913	2.2e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HBBFKNIG_00914	1.49e-178	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HBBFKNIG_00915	1.23e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HBBFKNIG_00917	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HBBFKNIG_00918	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HBBFKNIG_00919	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HBBFKNIG_00920	1.13e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HBBFKNIG_00921	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HBBFKNIG_00922	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HBBFKNIG_00923	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HBBFKNIG_00924	9.48e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HBBFKNIG_00925	1.08e-101	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HBBFKNIG_00926	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_00927	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBBFKNIG_00928	4.49e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HBBFKNIG_00929	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HBBFKNIG_00930	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HBBFKNIG_00931	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HBBFKNIG_00932	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HBBFKNIG_00934	3.93e-182	ysnF	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_00935	5.72e-99	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HBBFKNIG_00937	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HBBFKNIG_00938	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HBBFKNIG_00939	3.91e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HBBFKNIG_00940	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HBBFKNIG_00941	4.3e-255	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HBBFKNIG_00942	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HBBFKNIG_00943	1.08e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HBBFKNIG_00944	1.11e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HBBFKNIG_00945	1.47e-285	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HBBFKNIG_00946	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HBBFKNIG_00947	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HBBFKNIG_00948	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HBBFKNIG_00949	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HBBFKNIG_00950	4.77e-116	ysxD	-	-	-	-	-	-	-
HBBFKNIG_00951	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HBBFKNIG_00952	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HBBFKNIG_00953	3.11e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HBBFKNIG_00954	5.02e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HBBFKNIG_00955	3.7e-233	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HBBFKNIG_00956	3.53e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HBBFKNIG_00957	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HBBFKNIG_00958	2.39e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBBFKNIG_00959	1.53e-35	-	-	-	-	-	-	-	-
HBBFKNIG_00960	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HBBFKNIG_00961	1.23e-312	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HBBFKNIG_00962	2.53e-161	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HBBFKNIG_00963	1.66e-208	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HBBFKNIG_00964	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HBBFKNIG_00965	3.4e-162	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HBBFKNIG_00966	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HBBFKNIG_00967	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HBBFKNIG_00968	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HBBFKNIG_00969	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HBBFKNIG_00970	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HBBFKNIG_00971	1.83e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HBBFKNIG_00972	1.25e-206	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HBBFKNIG_00973	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HBBFKNIG_00974	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HBBFKNIG_00975	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HBBFKNIG_00976	1.73e-136	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HBBFKNIG_00977	5.59e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HBBFKNIG_00978	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HBBFKNIG_00979	1.43e-208	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HBBFKNIG_00980	1.44e-122	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HBBFKNIG_00981	9.61e-290	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HBBFKNIG_00982	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HBBFKNIG_00983	9.4e-198	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HBBFKNIG_00984	1.32e-271	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HBBFKNIG_00985	5.02e-214	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HBBFKNIG_00986	7.28e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HBBFKNIG_00987	8.27e-163	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HBBFKNIG_00988	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HBBFKNIG_00989	4.41e-68	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
HBBFKNIG_00991	6.39e-150	yrzF	-	-	T	-	-	-	serine threonine protein kinase
HBBFKNIG_00992	2.65e-246	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HBBFKNIG_00993	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
HBBFKNIG_00994	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HBBFKNIG_00995	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HBBFKNIG_00996	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HBBFKNIG_00997	4.84e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HBBFKNIG_00998	2.46e-247	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HBBFKNIG_00999	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HBBFKNIG_01000	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HBBFKNIG_01001	5.95e-96	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HBBFKNIG_01002	5.83e-143	yrbG	-	-	S	-	-	-	membrane
HBBFKNIG_01003	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBBFKNIG_01004	5.53e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HBBFKNIG_01005	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBBFKNIG_01006	3.77e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HBBFKNIG_01007	8.79e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HBBFKNIG_01008	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HBBFKNIG_01009	1.46e-117	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HBBFKNIG_01010	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBBFKNIG_01011	3.91e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HBBFKNIG_01012	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HBBFKNIG_01014	1e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HBBFKNIG_01015	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HBBFKNIG_01016	3.8e-175	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HBBFKNIG_01017	9.91e-303	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HBBFKNIG_01018	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_01019	7.63e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HBBFKNIG_01020	4.83e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HBBFKNIG_01021	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HBBFKNIG_01022	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HBBFKNIG_01023	1.14e-104	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_01024	8.4e-42	yrzR	-	-	-	-	-	-	-
HBBFKNIG_01025	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HBBFKNIG_01026	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBBFKNIG_01027	6.53e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBBFKNIG_01028	2.12e-186	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HBBFKNIG_01029	8.99e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HBBFKNIG_01030	7.23e-241	yrrI	-	-	S	-	-	-	AI-2E family transporter
HBBFKNIG_01031	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HBBFKNIG_01032	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HBBFKNIG_01033	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HBBFKNIG_01034	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HBBFKNIG_01035	8.76e-241	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBBFKNIG_01036	1.98e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HBBFKNIG_01037	2.46e-219	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HBBFKNIG_01038	2.67e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HBBFKNIG_01039	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HBBFKNIG_01040	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HBBFKNIG_01041	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HBBFKNIG_01042	2.87e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HBBFKNIG_01043	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HBBFKNIG_01044	2.42e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HBBFKNIG_01045	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBBFKNIG_01046	2.36e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HBBFKNIG_01047	8.19e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HBBFKNIG_01048	1.99e-48	yrhC	-	-	S	-	-	-	YrhC-like protein
HBBFKNIG_01049	1.73e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HBBFKNIG_01050	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HBBFKNIG_01051	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HBBFKNIG_01052	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HBBFKNIG_01054	1.33e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HBBFKNIG_01055	2.49e-123	yrhH	-	-	Q	-	-	-	methyltransferase
HBBFKNIG_01056	4.57e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HBBFKNIG_01057	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HBBFKNIG_01058	2.58e-58	yrhK	-	-	S	-	-	-	YrhK-like protein
HBBFKNIG_01059	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HBBFKNIG_01060	2.47e-191	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HBBFKNIG_01061	9.97e-114	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBBFKNIG_01062	2.31e-191	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
HBBFKNIG_01063	7.67e-135	yrhP	-	-	E	-	-	-	LysE type translocator
HBBFKNIG_01064	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HBBFKNIG_01065	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
HBBFKNIG_01066	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HBBFKNIG_01067	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
HBBFKNIG_01068	1.01e-166	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HBBFKNIG_01069	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HBBFKNIG_01070	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HBBFKNIG_01071	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HBBFKNIG_01072	5.39e-250	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HBBFKNIG_01073	1.11e-33	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
HBBFKNIG_01074	9.08e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HBBFKNIG_01075	2e-63	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HBBFKNIG_01076	3.54e-35	yraE	-	-	-	ko:K06440	-	ko00000	-
HBBFKNIG_01077	6.88e-279	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HBBFKNIG_01078	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
HBBFKNIG_01079	1.2e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
HBBFKNIG_01080	5.45e-86	-	-	-	E	-	-	-	Glyoxalase-like domain
HBBFKNIG_01081	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
HBBFKNIG_01082	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
HBBFKNIG_01083	1.32e-189	-	-	-	S	-	-	-	Alpha beta hydrolase
HBBFKNIG_01084	1.45e-55	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBBFKNIG_01085	1.92e-200	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HBBFKNIG_01086	5.72e-238	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
HBBFKNIG_01087	3.04e-122	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBBFKNIG_01088	1.08e-168	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HBBFKNIG_01089	1.33e-161	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HBBFKNIG_01090	4.15e-189	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HBBFKNIG_01091	9.97e-245	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HBBFKNIG_01092	1.42e-210	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HBBFKNIG_01093	1.66e-117	yrdA	-	-	S	-	-	-	DinB family
HBBFKNIG_01095	1.48e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
HBBFKNIG_01096	7.38e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
HBBFKNIG_01097	2.33e-282	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HBBFKNIG_01098	1.16e-25	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HBBFKNIG_01099	9.74e-103	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
HBBFKNIG_01100	9.34e-176	azlC	-	-	E	-	-	-	AzlC protein
HBBFKNIG_01101	3.26e-65	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
HBBFKNIG_01102	2.03e-291	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HBBFKNIG_01103	2.15e-206	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
HBBFKNIG_01104	1.44e-86	yodA	-	-	S	-	-	-	tautomerase
HBBFKNIG_01105	8.16e-211	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HBBFKNIG_01106	1.32e-248	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
HBBFKNIG_01107	2.83e-203	-	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_01108	5.73e-215	yrdR	-	-	EG	-	-	-	EamA-like transporter family
HBBFKNIG_01109	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
HBBFKNIG_01110	1.39e-295	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HBBFKNIG_01111	6.19e-108	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HBBFKNIG_01112	2.08e-266	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_01113	1.69e-192	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HBBFKNIG_01114	9.6e-160	-	-	-	EGP	-	-	-	Necrosis inducing protein (NPP1)
HBBFKNIG_01117	1.47e-33	-	-	-	-	-	-	-	-
HBBFKNIG_01118	1.64e-63	-	-	-	-	-	-	-	-
HBBFKNIG_01119	1.98e-206	-	-	-	S	-	-	-	Bacterial EndoU nuclease
HBBFKNIG_01120	4.74e-248	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
HBBFKNIG_01122	3.8e-78	-	-	-	P	-	-	-	Rhodanese Homology Domain
HBBFKNIG_01123	3.27e-81	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBBFKNIG_01124	8.63e-102	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HBBFKNIG_01125	2.33e-125	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
HBBFKNIG_01126	5.4e-18	cisA2	-	-	L	ko:K06400	-	ko00000	recombinase activity
HBBFKNIG_01127	3.3e-116	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HBBFKNIG_01129	1.1e-125	yqaC	-	-	F	-	-	-	adenylate kinase activity
HBBFKNIG_01130	2.25e-118	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HBBFKNIG_01131	4.54e-205	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HBBFKNIG_01132	1.02e-18	xepA	-	-	-	-	-	-	-
HBBFKNIG_01133	2.3e-86	-	-	-	S	-	-	-	Bacteriophage holin family
HBBFKNIG_01134	3.66e-08	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HBBFKNIG_01135	2.59e-50	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HBBFKNIG_01137	1.69e-40	-	-	-	-	-	-	-	-
HBBFKNIG_01138	1.62e-35	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HBBFKNIG_01139	8.97e-171	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HBBFKNIG_01140	3.36e-78	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HBBFKNIG_01141	1.01e-129	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HBBFKNIG_01142	1.02e-280	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HBBFKNIG_01143	1.39e-161	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
HBBFKNIG_01144	9.54e-302	yrkQ	-	-	T	-	-	-	Histidine kinase
HBBFKNIG_01145	2.15e-90	psiE	-	-	S	ko:K13256	-	ko00000	Protein PsiE homolog
HBBFKNIG_01147	7.53e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBBFKNIG_01148	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HBBFKNIG_01149	1.43e-165	-	-	-	-	-	-	-	-
HBBFKNIG_01150	7.31e-215	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
HBBFKNIG_01151	1.27e-132	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HBBFKNIG_01152	9.35e-174	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HBBFKNIG_01153	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HBBFKNIG_01155	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HBBFKNIG_01156	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HBBFKNIG_01157	2.83e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HBBFKNIG_01158	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HBBFKNIG_01159	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HBBFKNIG_01160	1.61e-131	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HBBFKNIG_01161	1.14e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HBBFKNIG_01162	1.39e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
HBBFKNIG_01163	2.69e-189	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBBFKNIG_01164	9.06e-136	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HBBFKNIG_01165	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HBBFKNIG_01166	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HBBFKNIG_01167	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
HBBFKNIG_01168	6.73e-243	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HBBFKNIG_01169	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HBBFKNIG_01170	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HBBFKNIG_01171	3.18e-282	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HBBFKNIG_01172	7.06e-70	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HBBFKNIG_01173	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HBBFKNIG_01174	1.96e-274	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HBBFKNIG_01175	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HBBFKNIG_01176	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HBBFKNIG_01177	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HBBFKNIG_01178	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HBBFKNIG_01179	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HBBFKNIG_01180	1.68e-179	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HBBFKNIG_01181	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HBBFKNIG_01182	1.91e-199	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HBBFKNIG_01183	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HBBFKNIG_01184	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HBBFKNIG_01185	9.29e-291	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HBBFKNIG_01186	1.61e-187	yqfA	-	-	S	-	-	-	UPF0365 protein
HBBFKNIG_01187	1.49e-77	yqfB	-	-	-	-	-	-	-
HBBFKNIG_01188	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HBBFKNIG_01189	6e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HBBFKNIG_01190	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HBBFKNIG_01192	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HBBFKNIG_01193	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HBBFKNIG_01194	4.75e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HBBFKNIG_01195	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HBBFKNIG_01196	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBBFKNIG_01197	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
HBBFKNIG_01198	1.24e-185	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HBBFKNIG_01199	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HBBFKNIG_01200	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HBBFKNIG_01201	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
HBBFKNIG_01202	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HBBFKNIG_01203	3.49e-113	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HBBFKNIG_01204	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HBBFKNIG_01205	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HBBFKNIG_01206	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HBBFKNIG_01207	5.67e-149	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HBBFKNIG_01208	1.79e-267	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBBFKNIG_01209	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HBBFKNIG_01210	3.6e-40	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HBBFKNIG_01211	1.09e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HBBFKNIG_01212	1.21e-213	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HBBFKNIG_01213	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HBBFKNIG_01214	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBBFKNIG_01215	2.47e-106	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HBBFKNIG_01216	1.95e-140	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HBBFKNIG_01217	2.04e-81	yqfX	-	-	S	-	-	-	membrane
HBBFKNIG_01218	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HBBFKNIG_01219	1.64e-62	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HBBFKNIG_01220	2.74e-168	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HBBFKNIG_01221	1.66e-100	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HBBFKNIG_01222	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HBBFKNIG_01223	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HBBFKNIG_01224	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HBBFKNIG_01225	1.06e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HBBFKNIG_01226	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HBBFKNIG_01227	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HBBFKNIG_01228	9.78e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HBBFKNIG_01229	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HBBFKNIG_01230	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
HBBFKNIG_01231	3.42e-68	yqzD	-	-	-	-	-	-	-
HBBFKNIG_01233	2.53e-251	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
HBBFKNIG_01234	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HBBFKNIG_01235	2.29e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBBFKNIG_01236	3.38e-14	yqgO	-	-	-	-	-	-	-
HBBFKNIG_01237	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
HBBFKNIG_01238	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
HBBFKNIG_01239	2.81e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HBBFKNIG_01240	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HBBFKNIG_01241	4.64e-278	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HBBFKNIG_01242	1.81e-254	yqgU	-	-	-	-	-	-	-
HBBFKNIG_01243	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
HBBFKNIG_01244	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HBBFKNIG_01245	1.07e-155	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HBBFKNIG_01246	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HBBFKNIG_01247	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HBBFKNIG_01249	2.79e-189	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HBBFKNIG_01250	5.77e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HBBFKNIG_01251	7.17e-232	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HBBFKNIG_01252	1.83e-256	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HBBFKNIG_01253	3.4e-216	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HBBFKNIG_01254	4.39e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HBBFKNIG_01255	7.66e-91	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
HBBFKNIG_01256	2.43e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HBBFKNIG_01257	7.11e-47	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HBBFKNIG_01258	3.78e-57	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HBBFKNIG_01259	4.9e-37	yqzE	-	-	S	-	-	-	YqzE-like protein
HBBFKNIG_01260	2.51e-68	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HBBFKNIG_01261	2.98e-151	yqxM	-	-	-	ko:K19433	-	ko00000	-
HBBFKNIG_01262	1e-95	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HBBFKNIG_01263	1.28e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HBBFKNIG_01264	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HBBFKNIG_01265	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HBBFKNIG_01266	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HBBFKNIG_01267	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HBBFKNIG_01268	5.49e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HBBFKNIG_01269	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HBBFKNIG_01270	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HBBFKNIG_01271	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HBBFKNIG_01272	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HBBFKNIG_01273	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HBBFKNIG_01274	2.44e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HBBFKNIG_01275	5.18e-81	yqhP	-	-	-	-	-	-	-
HBBFKNIG_01276	5.16e-221	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HBBFKNIG_01277	4.64e-120	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HBBFKNIG_01278	4.75e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HBBFKNIG_01279	8.58e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HBBFKNIG_01280	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HBBFKNIG_01281	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HBBFKNIG_01282	1.22e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HBBFKNIG_01283	5.69e-111	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HBBFKNIG_01284	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HBBFKNIG_01285	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HBBFKNIG_01286	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HBBFKNIG_01287	3.66e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HBBFKNIG_01288	1.73e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HBBFKNIG_01289	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HBBFKNIG_01290	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HBBFKNIG_01291	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HBBFKNIG_01292	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_01293	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HBBFKNIG_01294	1.51e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HBBFKNIG_01295	3.55e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HBBFKNIG_01296	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HBBFKNIG_01297	1.2e-208	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HBBFKNIG_01298	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HBBFKNIG_01299	5.06e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HBBFKNIG_01300	8.85e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HBBFKNIG_01301	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HBBFKNIG_01302	1.26e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HBBFKNIG_01303	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HBBFKNIG_01305	4.67e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HBBFKNIG_01306	7.85e-36	-	-	-	-	-	-	-	-
HBBFKNIG_01307	1.14e-138	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HBBFKNIG_01308	3.39e-168	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HBBFKNIG_01309	3.68e-277	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HBBFKNIG_01310	2.81e-198	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HBBFKNIG_01311	1.65e-266	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HBBFKNIG_01312	7.54e-264	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HBBFKNIG_01313	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HBBFKNIG_01314	1.46e-207	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HBBFKNIG_01315	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HBBFKNIG_01316	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HBBFKNIG_01317	1.74e-198	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HBBFKNIG_01318	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HBBFKNIG_01319	5.62e-254	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HBBFKNIG_01320	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HBBFKNIG_01321	1.92e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HBBFKNIG_01322	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HBBFKNIG_01323	3.09e-287	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HBBFKNIG_01324	8.69e-193	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
HBBFKNIG_01325	1.03e-265	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_01326	4.94e-213	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HBBFKNIG_01327	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HBBFKNIG_01328	3.37e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HBBFKNIG_01329	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HBBFKNIG_01330	1.28e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HBBFKNIG_01331	1.73e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HBBFKNIG_01332	2.41e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_01334	1.34e-94	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HBBFKNIG_01335	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HBBFKNIG_01336	3.04e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HBBFKNIG_01337	1.15e-177	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
HBBFKNIG_01338	2.54e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HBBFKNIG_01339	3.06e-32	yqzJ	-	-	-	-	-	-	-
HBBFKNIG_01340	1.45e-296	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBBFKNIG_01341	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HBBFKNIG_01342	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HBBFKNIG_01343	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HBBFKNIG_01344	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HBBFKNIG_01345	3.17e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HBBFKNIG_01346	7.02e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HBBFKNIG_01347	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HBBFKNIG_01348	1.96e-189	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBBFKNIG_01349	2.58e-226	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HBBFKNIG_01350	6.89e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBBFKNIG_01351	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HBBFKNIG_01352	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HBBFKNIG_01353	3.15e-94	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBBFKNIG_01355	9.28e-286	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
HBBFKNIG_01357	3.31e-303	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBBFKNIG_01358	3.23e-66	yqiX	-	-	S	-	-	-	YolD-like protein
HBBFKNIG_01359	9.06e-112	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HBBFKNIG_01360	2.25e-78	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HBBFKNIG_01361	2.66e-247	yqkA	-	-	K	-	-	-	GrpB protein
HBBFKNIG_01362	5.08e-72	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HBBFKNIG_01363	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HBBFKNIG_01364	3.79e-219	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HBBFKNIG_01365	6.61e-26	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HBBFKNIG_01366	3.61e-215	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HBBFKNIG_01367	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HBBFKNIG_01368	4.76e-119	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HBBFKNIG_01369	3.99e-278	yqxK	-	-	L	-	-	-	DNA helicase
HBBFKNIG_01370	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_01371	5.09e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HBBFKNIG_01372	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HBBFKNIG_01373	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HBBFKNIG_01374	1.32e-307	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HBBFKNIG_01375	7.27e-42	yqkK	-	-	-	-	-	-	-
HBBFKNIG_01376	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HBBFKNIG_01377	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HBBFKNIG_01378	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HBBFKNIG_01379	3.91e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HBBFKNIG_01380	6.8e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HBBFKNIG_01381	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HBBFKNIG_01382	3.37e-271	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HBBFKNIG_01383	3e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HBBFKNIG_01384	1.37e-99	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HBBFKNIG_01385	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBBFKNIG_01386	6.68e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HBBFKNIG_01387	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
HBBFKNIG_01388	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HBBFKNIG_01389	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HBBFKNIG_01390	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HBBFKNIG_01391	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HBBFKNIG_01392	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HBBFKNIG_01393	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HBBFKNIG_01394	3.64e-191	ypuA	-	-	S	-	-	-	Secreted protein
HBBFKNIG_01395	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBBFKNIG_01397	2.49e-43	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
HBBFKNIG_01398	3.39e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HBBFKNIG_01399	5.98e-72	ypuD	-	-	-	-	-	-	-
HBBFKNIG_01400	1.02e-260	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBBFKNIG_01401	7.16e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HBBFKNIG_01402	2.1e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBBFKNIG_01403	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HBBFKNIG_01404	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBBFKNIG_01405	2.41e-118	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HBBFKNIG_01406	2.6e-161	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HBBFKNIG_01407	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HBBFKNIG_01408	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HBBFKNIG_01409	2.37e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HBBFKNIG_01410	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HBBFKNIG_01411	4.99e-113	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HBBFKNIG_01412	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HBBFKNIG_01413	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HBBFKNIG_01414	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HBBFKNIG_01415	2.7e-278	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HBBFKNIG_01416	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_01417	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_01418	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBBFKNIG_01419	6.23e-247	rsiX	-	-	-	-	-	-	-
HBBFKNIG_01420	6.53e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HBBFKNIG_01421	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBBFKNIG_01422	6.2e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HBBFKNIG_01423	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HBBFKNIG_01424	1.82e-254	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HBBFKNIG_01425	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HBBFKNIG_01426	1.02e-127	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HBBFKNIG_01427	6.42e-136	ypbE	-	-	M	-	-	-	Lysin motif
HBBFKNIG_01428	1.66e-105	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HBBFKNIG_01429	8.38e-186	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HBBFKNIG_01430	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HBBFKNIG_01431	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HBBFKNIG_01432	2.62e-224	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HBBFKNIG_01433	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HBBFKNIG_01434	1.4e-207	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HBBFKNIG_01435	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HBBFKNIG_01436	2.46e-139	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HBBFKNIG_01437	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HBBFKNIG_01438	1.94e-144	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HBBFKNIG_01439	1.57e-261	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HBBFKNIG_01440	1.98e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HBBFKNIG_01441	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
HBBFKNIG_01442	7.5e-132	yphA	-	-	-	-	-	-	-
HBBFKNIG_01443	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
HBBFKNIG_01444	8.69e-40	ypzH	-	-	-	-	-	-	-
HBBFKNIG_01445	5.72e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HBBFKNIG_01446	6.32e-231	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HBBFKNIG_01447	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HBBFKNIG_01448	7.16e-175	yphF	-	-	-	-	-	-	-
HBBFKNIG_01449	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HBBFKNIG_01450	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HBBFKNIG_01451	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HBBFKNIG_01452	4.23e-45	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HBBFKNIG_01453	1.02e-176	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HBBFKNIG_01454	1.34e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HBBFKNIG_01455	2.37e-248	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HBBFKNIG_01456	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HBBFKNIG_01457	3.03e-182	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HBBFKNIG_01458	5.88e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HBBFKNIG_01459	1.57e-260	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HBBFKNIG_01460	1.98e-83	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HBBFKNIG_01461	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBBFKNIG_01462	2.03e-228	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBBFKNIG_01463	7.24e-146	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HBBFKNIG_01464	1.57e-150	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HBBFKNIG_01465	8.95e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HBBFKNIG_01466	1.28e-184	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HBBFKNIG_01467	1.83e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HBBFKNIG_01468	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HBBFKNIG_01469	3.7e-297	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HBBFKNIG_01470	1.39e-294	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HBBFKNIG_01471	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HBBFKNIG_01472	3.21e-99	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HBBFKNIG_01473	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HBBFKNIG_01474	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HBBFKNIG_01475	3.31e-190	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HBBFKNIG_01476	3.84e-124	ypjA	-	-	S	-	-	-	membrane
HBBFKNIG_01477	5.62e-182	ypjB	-	-	S	-	-	-	sporulation protein
HBBFKNIG_01478	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBBFKNIG_01479	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HBBFKNIG_01480	8.04e-188	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HBBFKNIG_01481	2.52e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HBBFKNIG_01482	1.89e-166	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HBBFKNIG_01483	2.34e-265	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HBBFKNIG_01484	3.7e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HBBFKNIG_01485	4e-233	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HBBFKNIG_01486	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HBBFKNIG_01487	1.29e-198	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HBBFKNIG_01488	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HBBFKNIG_01489	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HBBFKNIG_01490	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HBBFKNIG_01491	5.36e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_01492	1.78e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HBBFKNIG_01493	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HBBFKNIG_01494	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HBBFKNIG_01495	1.02e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBBFKNIG_01496	1.67e-120	ypoC	-	-	-	-	-	-	-
HBBFKNIG_01497	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HBBFKNIG_01498	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HBBFKNIG_01499	2.52e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HBBFKNIG_01502	2e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
HBBFKNIG_01503	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
HBBFKNIG_01504	1.45e-66	yppG	-	-	S	-	-	-	YppG-like protein
HBBFKNIG_01505	1.24e-94	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HBBFKNIG_01506	5.3e-110	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HBBFKNIG_01507	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HBBFKNIG_01508	1.56e-295	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HBBFKNIG_01509	5.9e-129	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HBBFKNIG_01510	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HBBFKNIG_01511	4.71e-285	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HBBFKNIG_01513	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HBBFKNIG_01514	5.4e-175	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBBFKNIG_01515	9.9e-202	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HBBFKNIG_01516	7.8e-238	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
HBBFKNIG_01517	1.15e-236	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HBBFKNIG_01518	1.47e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HBBFKNIG_01519	2.07e-217	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HBBFKNIG_01520	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HBBFKNIG_01521	5.51e-127	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HBBFKNIG_01522	5.8e-290	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HBBFKNIG_01523	6.2e-264	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HBBFKNIG_01524	3.33e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HBBFKNIG_01526	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HBBFKNIG_01527	3.35e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HBBFKNIG_01528	1.08e-11	-	-	-	-	-	-	-	-
HBBFKNIG_01529	1.08e-211	ypcP	-	-	L	-	-	-	5'3' exonuclease
HBBFKNIG_01530	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
HBBFKNIG_01531	1.54e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HBBFKNIG_01532	2.68e-135	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HBBFKNIG_01533	5.46e-161	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HBBFKNIG_01534	4.64e-40	ypeQ	-	-	S	-	-	-	Zinc-finger
HBBFKNIG_01535	2.13e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HBBFKNIG_01536	1.17e-22	degR	-	-	-	-	-	-	-
HBBFKNIG_01537	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HBBFKNIG_01538	3.67e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HBBFKNIG_01539	1.28e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBBFKNIG_01540	7.69e-115	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HBBFKNIG_01541	1.75e-133	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HBBFKNIG_01542	6.98e-205	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HBBFKNIG_01543	5.12e-252	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
HBBFKNIG_01544	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HBBFKNIG_01545	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HBBFKNIG_01546	9.39e-182	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HBBFKNIG_01547	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
HBBFKNIG_01548	1.48e-119	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HBBFKNIG_01549	1.65e-199	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HBBFKNIG_01550	1.93e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBBFKNIG_01551	6.68e-143	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HBBFKNIG_01552	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HBBFKNIG_01553	1.75e-230	yplP	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_01554	2.46e-308	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBBFKNIG_01555	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HBBFKNIG_01556	3.23e-139	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HBBFKNIG_01557	5.21e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HBBFKNIG_01558	1.13e-127	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_01559	2.13e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
HBBFKNIG_01560	3.33e-288	mepA	-	-	V	-	-	-	MATE efflux family protein
HBBFKNIG_01561	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
HBBFKNIG_01562	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBBFKNIG_01563	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HBBFKNIG_01564	1.66e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HBBFKNIG_01565	2.31e-279	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HBBFKNIG_01566	2.69e-227	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HBBFKNIG_01567	1.26e-82	cgeA	-	-	-	ko:K06319	-	ko00000	-
HBBFKNIG_01568	1.06e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
HBBFKNIG_01569	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HBBFKNIG_01570	2.4e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HBBFKNIG_01572	9.46e-315	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBBFKNIG_01573	6.6e-159	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBBFKNIG_01574	7.76e-152	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HBBFKNIG_01575	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HBBFKNIG_01576	2.93e-194	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HBBFKNIG_01577	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HBBFKNIG_01578	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HBBFKNIG_01579	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HBBFKNIG_01580	1.29e-159	yodN	-	-	-	-	-	-	-
HBBFKNIG_01582	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
HBBFKNIG_01583	2.71e-136	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HBBFKNIG_01584	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
HBBFKNIG_01585	2.08e-12	-	-	-	-	-	-	-	-
HBBFKNIG_01586	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HBBFKNIG_01587	2.69e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HBBFKNIG_01588	4.86e-41	yodI	-	-	-	-	-	-	-
HBBFKNIG_01589	5.24e-167	yodH	-	-	Q	-	-	-	Methyltransferase
HBBFKNIG_01590	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HBBFKNIG_01591	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBBFKNIG_01592	4.77e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HBBFKNIG_01593	5.38e-220	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HBBFKNIG_01594	7.28e-144	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HBBFKNIG_01595	1.11e-139	yodC	-	-	C	-	-	-	nitroreductase
HBBFKNIG_01596	3.74e-73	yodB	-	-	K	-	-	-	transcriptional
HBBFKNIG_01597	3.27e-83	iolK	-	-	S	-	-	-	tautomerase
HBBFKNIG_01598	2.27e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HBBFKNIG_01599	9.2e-13	-	-	-	-	-	-	-	-
HBBFKNIG_01600	8.34e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HBBFKNIG_01601	8.13e-208	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HBBFKNIG_01602	3.08e-57	-	-	-	-	-	-	-	-
HBBFKNIG_01603	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HBBFKNIG_01604	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HBBFKNIG_01605	1.01e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HBBFKNIG_01606	1.69e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HBBFKNIG_01608	2.14e-141	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HBBFKNIG_01609	3.25e-293	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HBBFKNIG_01610	1.3e-267	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HBBFKNIG_01611	6.01e-141	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBBFKNIG_01612	1.33e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HBBFKNIG_01613	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HBBFKNIG_01614	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HBBFKNIG_01615	2.59e-264	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HBBFKNIG_01616	2.72e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HBBFKNIG_01617	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HBBFKNIG_01618	3.91e-211	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HBBFKNIG_01619	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HBBFKNIG_01620	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HBBFKNIG_01621	1.91e-42	yozC	-	-	-	-	-	-	-
HBBFKNIG_01622	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
HBBFKNIG_01623	1.83e-49	yocN	-	-	-	-	-	-	-
HBBFKNIG_01624	2.94e-55	yozN	-	-	-	-	-	-	-
HBBFKNIG_01625	6.6e-115	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HBBFKNIG_01626	5.79e-43	-	-	-	-	-	-	-	-
HBBFKNIG_01627	3.53e-69	yocL	-	-	-	-	-	-	-
HBBFKNIG_01628	2.87e-107	yocK	-	-	T	-	-	-	general stress protein
HBBFKNIG_01629	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBBFKNIG_01631	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HBBFKNIG_01632	9.63e-174	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HBBFKNIG_01634	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBBFKNIG_01635	7.91e-249	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_01636	1.14e-257	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HBBFKNIG_01637	3.72e-238	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HBBFKNIG_01638	6.27e-121	yocC	-	-	-	-	-	-	-
HBBFKNIG_01639	2.05e-182	-	-	-	-	-	-	-	-
HBBFKNIG_01640	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HBBFKNIG_01641	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HBBFKNIG_01642	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HBBFKNIG_01643	4.27e-120	yobW	-	-	-	-	-	-	-
HBBFKNIG_01644	3.76e-218	yobV	-	-	K	-	-	-	WYL domain
HBBFKNIG_01645	2.89e-110	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HBBFKNIG_01646	1.44e-164	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HBBFKNIG_01647	1.16e-105	yobS	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_01648	1.63e-21	-	-	-	J	-	-	-	FR47-like protein
HBBFKNIG_01649	1.38e-170	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HBBFKNIG_01650	5.21e-71	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HBBFKNIG_01651	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
HBBFKNIG_01652	9.75e-133	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HBBFKNIG_01653	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HBBFKNIG_01654	2.24e-110	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HBBFKNIG_01655	5.34e-62	-	-	-	-	-	-	-	-
HBBFKNIG_01656	1.15e-52	-	-	-	-	-	-	-	-
HBBFKNIG_01658	7.53e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HBBFKNIG_01659	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HBBFKNIG_01662	4.22e-214	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HBBFKNIG_01663	1.7e-147	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
HBBFKNIG_01664	1.61e-101	yoaW	-	-	-	-	-	-	-
HBBFKNIG_01665	1.76e-199	yoaV	-	-	EG	-	-	-	EamA-like transporter family
HBBFKNIG_01666	1.91e-202	yoaU	-	-	K	-	-	-	LysR substrate binding domain
HBBFKNIG_01667	5.46e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
HBBFKNIG_01668	7.19e-41	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_01669	1.53e-96	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HBBFKNIG_01670	1.73e-216	yoaR	-	-	V	-	-	-	vancomycin resistance protein
HBBFKNIG_01671	2.86e-108	-	-	-	-	-	-	-	-
HBBFKNIG_01674	6.26e-293	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HBBFKNIG_01676	1.22e-70	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HBBFKNIG_01677	1.23e-251	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
HBBFKNIG_01678	2.09e-144	yoaK	-	-	S	-	-	-	Membrane
HBBFKNIG_01679	7.48e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
HBBFKNIG_01680	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HBBFKNIG_01681	5.91e-313	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HBBFKNIG_01682	1.43e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
HBBFKNIG_01683	6.99e-18	-	-	-	-	-	-	-	-
HBBFKNIG_01684	4.37e-46	yoaF	-	-	-	-	-	-	-
HBBFKNIG_01685	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBBFKNIG_01686	3.36e-234	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBBFKNIG_01687	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HBBFKNIG_01688	2.61e-299	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HBBFKNIG_01689	2.31e-122	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HBBFKNIG_01690	1e-171	yoxB	-	-	-	-	-	-	-
HBBFKNIG_01691	2.7e-51	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HBBFKNIG_01692	2.28e-159	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBBFKNIG_01693	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HBBFKNIG_01694	2.72e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBBFKNIG_01695	6.68e-262	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HBBFKNIG_01696	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_01697	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HBBFKNIG_01698	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HBBFKNIG_01699	2.42e-236	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HBBFKNIG_01700	2.81e-197	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_01701	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HBBFKNIG_01702	1.11e-45	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HBBFKNIG_01703	1.14e-124	-	-	-	L	-	-	-	Integrase
HBBFKNIG_01705	4.13e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HBBFKNIG_01706	2.3e-311	yoeA	-	-	V	-	-	-	MATE efflux family protein
HBBFKNIG_01707	1.45e-235	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HBBFKNIG_01708	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HBBFKNIG_01709	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBBFKNIG_01710	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBBFKNIG_01711	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBBFKNIG_01712	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBBFKNIG_01713	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
HBBFKNIG_01714	1.68e-81	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HBBFKNIG_01715	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HBBFKNIG_01716	1.06e-36	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
HBBFKNIG_01717	7.28e-266	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HBBFKNIG_01718	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HBBFKNIG_01719	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HBBFKNIG_01720	8.37e-42	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HBBFKNIG_01721	3.34e-212	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HBBFKNIG_01722	9.58e-172	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HBBFKNIG_01723	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HBBFKNIG_01724	3.01e-295	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
HBBFKNIG_01725	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
HBBFKNIG_01726	4.35e-207	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HBBFKNIG_01727	2.09e-104	yngA	-	-	S	-	-	-	membrane
HBBFKNIG_01728	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HBBFKNIG_01729	1.18e-315	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
HBBFKNIG_01730	7.91e-269	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
HBBFKNIG_01732	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
HBBFKNIG_01733	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HBBFKNIG_01734	1.06e-75	ynfC	-	-	-	-	-	-	-
HBBFKNIG_01735	1.82e-18	-	-	-	-	-	-	-	-
HBBFKNIG_01736	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HBBFKNIG_01737	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HBBFKNIG_01738	1.21e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HBBFKNIG_01739	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HBBFKNIG_01740	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HBBFKNIG_01741	6.65e-71	yneQ	-	-	-	-	-	-	-
HBBFKNIG_01742	5.7e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HBBFKNIG_01743	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HBBFKNIG_01745	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
HBBFKNIG_01746	8.82e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HBBFKNIG_01747	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HBBFKNIG_01748	3.27e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HBBFKNIG_01749	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HBBFKNIG_01750	2.35e-84	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HBBFKNIG_01751	2.3e-96	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HBBFKNIG_01752	3.57e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HBBFKNIG_01753	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HBBFKNIG_01754	1.18e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HBBFKNIG_01755	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HBBFKNIG_01756	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HBBFKNIG_01757	3.09e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HBBFKNIG_01758	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBBFKNIG_01759	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HBBFKNIG_01760	3.8e-143	yneB	-	-	L	-	-	-	resolvase
HBBFKNIG_01761	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HBBFKNIG_01762	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBBFKNIG_01763	1.49e-102	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HBBFKNIG_01764	3.79e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HBBFKNIG_01765	1.61e-175	yndL	-	-	S	-	-	-	Replication protein
HBBFKNIG_01767	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HBBFKNIG_01768	1.65e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HBBFKNIG_01769	1.99e-193	yndG	-	-	S	-	-	-	DoxX-like family
HBBFKNIG_01770	2.78e-273	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HBBFKNIG_01771	1.87e-248	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
HBBFKNIG_01772	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HBBFKNIG_01775	3.01e-102	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HBBFKNIG_01776	1.04e-94	-	-	-	-	-	-	-	-
HBBFKNIG_01777	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
HBBFKNIG_01780	1.33e-161	-	-	-	S	-	-	-	Domain of unknown function, YrpD
HBBFKNIG_01782	1.7e-250	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
HBBFKNIG_01783	5.55e-210	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HBBFKNIG_01785	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HBBFKNIG_01786	9.11e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
HBBFKNIG_01787	4.16e-279	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBBFKNIG_01788	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBBFKNIG_01789	1.24e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HBBFKNIG_01790	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HBBFKNIG_01791	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HBBFKNIG_01792	2.48e-275	xylR	-	-	GK	-	-	-	ROK family
HBBFKNIG_01793	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HBBFKNIG_01794	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HBBFKNIG_01796	3.88e-05	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HBBFKNIG_01797	2.14e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HBBFKNIG_01798	6.57e-29	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HBBFKNIG_01799	8.48e-12	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HBBFKNIG_01800	1.61e-93	-	-	-	S	-	-	-	CAAX protease self-immunity
HBBFKNIG_01801	3.38e-125	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HBBFKNIG_01802	3.58e-120	ynaC	-	-	-	-	-	-	-
HBBFKNIG_01803	1.56e-120	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
HBBFKNIG_01804	1.62e-48	-	-	-	-	-	-	-	-
HBBFKNIG_01805	1.11e-158	-	-	-	-	-	-	-	-
HBBFKNIG_01807	6.13e-14	-	-	-	-	-	-	-	-
HBBFKNIG_01809	2.78e-260	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
HBBFKNIG_01810	3.89e-67	-	-	-	M	-	-	-	nuclease activity
HBBFKNIG_01811	5.86e-54	-	-	-	-	-	-	-	-
HBBFKNIG_01812	3.69e-32	-	-	-	-	-	-	-	-
HBBFKNIG_01813	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HBBFKNIG_01814	4.05e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HBBFKNIG_01815	4.78e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HBBFKNIG_01816	1.82e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBBFKNIG_01817	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HBBFKNIG_01818	9.5e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HBBFKNIG_01819	1.84e-140	-	-	-	-	-	-	-	-
HBBFKNIG_01820	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBBFKNIG_01821	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBBFKNIG_01822	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HBBFKNIG_01823	1.2e-30	ymzA	-	-	-	-	-	-	-
HBBFKNIG_01824	5.65e-30	-	-	-	-	-	-	-	-
HBBFKNIG_01825	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HBBFKNIG_01826	3.95e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HBBFKNIG_01827	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
HBBFKNIG_01829	2.02e-66	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HBBFKNIG_01830	6.39e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
HBBFKNIG_01831	1.71e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HBBFKNIG_01832	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
HBBFKNIG_01834	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HBBFKNIG_01835	2.67e-207	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HBBFKNIG_01836	5.65e-81	ymzB	-	-	-	-	-	-	-
HBBFKNIG_01837	3.96e-294	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HBBFKNIG_01838	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
HBBFKNIG_01839	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HBBFKNIG_01840	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HBBFKNIG_01841	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBBFKNIG_01842	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HBBFKNIG_01843	6.35e-176	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HBBFKNIG_01844	1.61e-180	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
HBBFKNIG_01845	1.13e-312	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HBBFKNIG_01846	8.8e-303	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HBBFKNIG_01847	5.46e-51	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
HBBFKNIG_01848	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HBBFKNIG_01849	2.5e-231	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
HBBFKNIG_01851	1.2e-204	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HBBFKNIG_01852	1.57e-164	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
HBBFKNIG_01853	8.43e-141	pksA	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_01854	1.13e-126	ymcC	-	-	S	-	-	-	Membrane
HBBFKNIG_01855	1.76e-87	-	-	-	S	-	-	-	Regulatory protein YrvL
HBBFKNIG_01856	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HBBFKNIG_01857	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HBBFKNIG_01858	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HBBFKNIG_01859	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HBBFKNIG_01860	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HBBFKNIG_01861	2.68e-274	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HBBFKNIG_01862	2.9e-253	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HBBFKNIG_01863	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HBBFKNIG_01864	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HBBFKNIG_01865	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HBBFKNIG_01866	5.45e-278	pbpX	-	-	V	-	-	-	Beta-lactamase
HBBFKNIG_01867	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HBBFKNIG_01868	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HBBFKNIG_01869	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBBFKNIG_01870	3.05e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HBBFKNIG_01871	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HBBFKNIG_01872	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HBBFKNIG_01873	3.01e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HBBFKNIG_01874	5.59e-308	ymfH	-	-	S	-	-	-	zinc protease
HBBFKNIG_01875	3.86e-298	albE	-	-	S	-	-	-	Peptidase M16
HBBFKNIG_01876	2.95e-265	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_01877	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_01878	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HBBFKNIG_01879	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
HBBFKNIG_01880	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HBBFKNIG_01881	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBBFKNIG_01882	6.39e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBBFKNIG_01883	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HBBFKNIG_01884	1.12e-245	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBBFKNIG_01885	1.16e-140	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HBBFKNIG_01886	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HBBFKNIG_01887	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HBBFKNIG_01888	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HBBFKNIG_01889	3.71e-235	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HBBFKNIG_01890	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HBBFKNIG_01891	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HBBFKNIG_01892	4.48e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HBBFKNIG_01893	6.04e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HBBFKNIG_01894	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HBBFKNIG_01895	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HBBFKNIG_01896	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HBBFKNIG_01897	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HBBFKNIG_01898	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HBBFKNIG_01899	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HBBFKNIG_01900	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HBBFKNIG_01901	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBBFKNIG_01902	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HBBFKNIG_01903	5.62e-293	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HBBFKNIG_01904	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HBBFKNIG_01905	5.77e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HBBFKNIG_01906	1.1e-186	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HBBFKNIG_01907	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HBBFKNIG_01908	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HBBFKNIG_01909	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HBBFKNIG_01910	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HBBFKNIG_01911	4.66e-99	ylxL	-	-	-	-	-	-	-
HBBFKNIG_01912	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBBFKNIG_01913	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HBBFKNIG_01914	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HBBFKNIG_01915	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HBBFKNIG_01916	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HBBFKNIG_01917	1.49e-251	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HBBFKNIG_01918	1.55e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HBBFKNIG_01919	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HBBFKNIG_01920	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HBBFKNIG_01921	5.53e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HBBFKNIG_01922	1.21e-169	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HBBFKNIG_01923	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HBBFKNIG_01924	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HBBFKNIG_01925	4.35e-134	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HBBFKNIG_01926	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HBBFKNIG_01927	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HBBFKNIG_01928	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HBBFKNIG_01929	2.28e-77	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HBBFKNIG_01930	1.73e-176	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HBBFKNIG_01931	4.67e-95	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HBBFKNIG_01932	3.66e-311	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HBBFKNIG_01933	7.92e-81	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HBBFKNIG_01934	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HBBFKNIG_01935	1.59e-303	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HBBFKNIG_01936	7.8e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HBBFKNIG_01937	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HBBFKNIG_01938	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HBBFKNIG_01939	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HBBFKNIG_01940	2.16e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HBBFKNIG_01941	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HBBFKNIG_01942	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HBBFKNIG_01943	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HBBFKNIG_01944	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HBBFKNIG_01945	3.23e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HBBFKNIG_01946	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HBBFKNIG_01947	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HBBFKNIG_01948	6.32e-171	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HBBFKNIG_01949	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HBBFKNIG_01950	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HBBFKNIG_01951	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HBBFKNIG_01952	0.0	ylqG	-	-	-	-	-	-	-
HBBFKNIG_01953	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBBFKNIG_01954	1.63e-199	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HBBFKNIG_01955	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HBBFKNIG_01956	9.8e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HBBFKNIG_01957	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HBBFKNIG_01958	1.39e-79	ylqD	-	-	S	-	-	-	YlqD protein
HBBFKNIG_01959	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HBBFKNIG_01960	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HBBFKNIG_01961	3.95e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBBFKNIG_01962	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HBBFKNIG_01963	1.67e-114	-	-	-	-	-	-	-	-
HBBFKNIG_01964	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HBBFKNIG_01965	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HBBFKNIG_01966	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HBBFKNIG_01967	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBBFKNIG_01968	5.81e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HBBFKNIG_01969	3.09e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HBBFKNIG_01970	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HBBFKNIG_01971	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HBBFKNIG_01972	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBBFKNIG_01973	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HBBFKNIG_01974	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HBBFKNIG_01975	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HBBFKNIG_01976	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_01977	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HBBFKNIG_01978	4.7e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HBBFKNIG_01979	1.34e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HBBFKNIG_01980	1.12e-214	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HBBFKNIG_01981	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HBBFKNIG_01982	5.87e-179	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HBBFKNIG_01983	2.16e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HBBFKNIG_01984	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HBBFKNIG_01985	4.98e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HBBFKNIG_01986	4.8e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HBBFKNIG_01987	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBBFKNIG_01988	4.91e-284	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBBFKNIG_01989	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HBBFKNIG_01990	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HBBFKNIG_01991	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HBBFKNIG_01992	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
HBBFKNIG_01993	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HBBFKNIG_01994	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HBBFKNIG_01995	3.78e-107	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HBBFKNIG_01996	9.78e-186	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HBBFKNIG_01997	7.18e-186	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HBBFKNIG_01998	1.59e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HBBFKNIG_01999	2.62e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HBBFKNIG_02000	8.54e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HBBFKNIG_02001	3.44e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HBBFKNIG_02003	3.65e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HBBFKNIG_02004	6.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HBBFKNIG_02005	5.18e-222	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HBBFKNIG_02006	7.44e-183	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HBBFKNIG_02007	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HBBFKNIG_02008	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HBBFKNIG_02009	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HBBFKNIG_02010	1.79e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HBBFKNIG_02011	4.31e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HBBFKNIG_02012	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HBBFKNIG_02013	2.04e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HBBFKNIG_02014	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HBBFKNIG_02015	7.55e-82	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HBBFKNIG_02016	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HBBFKNIG_02017	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HBBFKNIG_02018	1.49e-178	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HBBFKNIG_02019	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HBBFKNIG_02020	4.47e-87	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HBBFKNIG_02021	9.03e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HBBFKNIG_02022	9.17e-204	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HBBFKNIG_02023	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
HBBFKNIG_02024	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HBBFKNIG_02025	6.37e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HBBFKNIG_02026	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBBFKNIG_02027	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBBFKNIG_02028	4.96e-219	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HBBFKNIG_02030	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HBBFKNIG_02031	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBBFKNIG_02032	2.82e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HBBFKNIG_02033	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
HBBFKNIG_02034	1.06e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_02035	2.23e-142	ylxW	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_02036	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HBBFKNIG_02037	3.74e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HBBFKNIG_02038	7.74e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HBBFKNIG_02039	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HBBFKNIG_02040	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HBBFKNIG_02041	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBBFKNIG_02042	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBBFKNIG_02043	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HBBFKNIG_02044	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HBBFKNIG_02045	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
HBBFKNIG_02046	4.76e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HBBFKNIG_02047	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HBBFKNIG_02048	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HBBFKNIG_02049	1.08e-212	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBBFKNIG_02050	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
HBBFKNIG_02051	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HBBFKNIG_02052	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HBBFKNIG_02053	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HBBFKNIG_02055	7.68e-153	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HBBFKNIG_02056	1.55e-18	yqgA	-	-	-	-	-	-	-
HBBFKNIG_02057	2.51e-237	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HBBFKNIG_02058	2.11e-175	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HBBFKNIG_02059	4.51e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HBBFKNIG_02060	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HBBFKNIG_02061	6.07e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HBBFKNIG_02062	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
HBBFKNIG_02063	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HBBFKNIG_02064	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HBBFKNIG_02065	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
HBBFKNIG_02066	4.39e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HBBFKNIG_02067	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HBBFKNIG_02068	6.56e-81	ylbA	-	-	S	-	-	-	YugN-like family
HBBFKNIG_02069	4.23e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HBBFKNIG_02070	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HBBFKNIG_02071	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HBBFKNIG_02072	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBBFKNIG_02073	3.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HBBFKNIG_02074	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HBBFKNIG_02075	1.21e-213	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HBBFKNIG_02076	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HBBFKNIG_02077	3.49e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HBBFKNIG_02078	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HBBFKNIG_02079	4.25e-220	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HBBFKNIG_02080	1.88e-111	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HBBFKNIG_02081	5.64e-315	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HBBFKNIG_02082	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HBBFKNIG_02083	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_02084	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
HBBFKNIG_02085	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HBBFKNIG_02086	1.06e-28	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HBBFKNIG_02087	5.7e-56	ylaE	-	-	-	-	-	-	-
HBBFKNIG_02089	1.76e-115	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBBFKNIG_02090	1.44e-56	ylaB	-	-	-	-	-	-	-
HBBFKNIG_02091	0.0	ylaA	-	-	-	-	-	-	-
HBBFKNIG_02092	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HBBFKNIG_02093	8.26e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HBBFKNIG_02094	2.36e-97	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HBBFKNIG_02095	3.18e-193	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HBBFKNIG_02096	4.48e-35	ykzI	-	-	-	-	-	-	-
HBBFKNIG_02097	5.28e-152	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HBBFKNIG_02098	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HBBFKNIG_02099	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HBBFKNIG_02101	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HBBFKNIG_02102	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HBBFKNIG_02103	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HBBFKNIG_02104	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HBBFKNIG_02105	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HBBFKNIG_02106	2.59e-139	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HBBFKNIG_02107	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HBBFKNIG_02108	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HBBFKNIG_02109	7.94e-185	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HBBFKNIG_02110	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HBBFKNIG_02111	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBBFKNIG_02112	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HBBFKNIG_02113	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HBBFKNIG_02114	1.7e-198	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HBBFKNIG_02115	3.77e-306	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HBBFKNIG_02116	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HBBFKNIG_02117	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HBBFKNIG_02118	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HBBFKNIG_02119	2.42e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HBBFKNIG_02120	2.23e-126	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBBFKNIG_02121	3.63e-72	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBBFKNIG_02122	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HBBFKNIG_02123	5.43e-52	ykoA	-	-	-	-	-	-	-
HBBFKNIG_02124	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HBBFKNIG_02125	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HBBFKNIG_02126	1.66e-214	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HBBFKNIG_02127	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_02128	1.84e-263	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HBBFKNIG_02129	6.1e-160	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_02130	3.17e-231	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBBFKNIG_02131	1.31e-150	yknW	-	-	S	-	-	-	Yip1 domain
HBBFKNIG_02132	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HBBFKNIG_02133	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HBBFKNIG_02134	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HBBFKNIG_02135	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HBBFKNIG_02136	3.44e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HBBFKNIG_02137	7.12e-312	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HBBFKNIG_02138	1.26e-243	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HBBFKNIG_02139	4.38e-140	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HBBFKNIG_02140	2.71e-197	yknT	-	-	-	ko:K06437	-	ko00000	-
HBBFKNIG_02141	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
HBBFKNIG_02142	4.94e-103	ykuV	-	-	CO	-	-	-	thiol-disulfide
HBBFKNIG_02143	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
HBBFKNIG_02144	4.78e-180	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HBBFKNIG_02145	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HBBFKNIG_02146	5.17e-272	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HBBFKNIG_02147	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HBBFKNIG_02148	2.95e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HBBFKNIG_02149	2.47e-222	ykuO	-	-	-	-	-	-	-
HBBFKNIG_02150	2.22e-107	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
HBBFKNIG_02151	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_02152	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
HBBFKNIG_02153	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HBBFKNIG_02154	2.62e-121	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HBBFKNIG_02155	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_02157	2.39e-296	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HBBFKNIG_02158	2.6e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBBFKNIG_02159	1.42e-211	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HBBFKNIG_02160	2.38e-114	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_02161	2.55e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_02162	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
HBBFKNIG_02163	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HBBFKNIG_02164	1.05e-22	-	-	-	-	-	-	-	-
HBBFKNIG_02165	1.4e-281	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HBBFKNIG_02166	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_02167	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HBBFKNIG_02168	2.18e-171	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HBBFKNIG_02169	1.15e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HBBFKNIG_02170	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBBFKNIG_02171	8.47e-160	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBBFKNIG_02172	2.13e-257	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HBBFKNIG_02173	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_02174	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBBFKNIG_02175	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HBBFKNIG_02176	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_02177	2.79e-167	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HBBFKNIG_02179	3.82e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_02181	1.3e-262	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HBBFKNIG_02182	3.99e-09	-	-	-	-	-	-	-	-
HBBFKNIG_02183	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HBBFKNIG_02184	2.36e-116	stoA	-	-	CO	-	-	-	thiol-disulfide
HBBFKNIG_02185	2.16e-300	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBBFKNIG_02186	4.32e-140	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HBBFKNIG_02187	5.91e-38	-	-	-	-	-	-	-	-
HBBFKNIG_02188	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_02189	3.12e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HBBFKNIG_02190	6.81e-202	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HBBFKNIG_02191	8.85e-47	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
HBBFKNIG_02192	2.37e-292	-	-	-	M	-	-	-	Glycosyl transferases group 1
HBBFKNIG_02193	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HBBFKNIG_02194	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HBBFKNIG_02195	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HBBFKNIG_02196	4.52e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HBBFKNIG_02197	7.06e-229	ykvI	-	-	S	-	-	-	membrane
HBBFKNIG_02198	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HBBFKNIG_02199	1.65e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HBBFKNIG_02200	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HBBFKNIG_02201	7.35e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HBBFKNIG_02202	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HBBFKNIG_02203	2.67e-91	eag	-	-	-	-	-	-	-
HBBFKNIG_02205	5.11e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HBBFKNIG_02206	3.54e-122	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HBBFKNIG_02207	5.28e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HBBFKNIG_02208	7.2e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HBBFKNIG_02209	9.72e-295	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HBBFKNIG_02210	2.67e-293	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HBBFKNIG_02211	1.99e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HBBFKNIG_02212	1.49e-292	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HBBFKNIG_02213	1.09e-251	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HBBFKNIG_02215	3.77e-113	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBBFKNIG_02216	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_02217	1.93e-243	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HBBFKNIG_02218	8.33e-31	ykzE	-	-	-	-	-	-	-
HBBFKNIG_02220	2.58e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HBBFKNIG_02221	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HBBFKNIG_02222	7.37e-158	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HBBFKNIG_02223	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HBBFKNIG_02224	6.63e-191	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HBBFKNIG_02225	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBBFKNIG_02226	7.67e-226	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HBBFKNIG_02227	3.44e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
HBBFKNIG_02228	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
HBBFKNIG_02229	1.46e-203	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HBBFKNIG_02230	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HBBFKNIG_02231	4.51e-236	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HBBFKNIG_02232	0.0	ykoS	-	-	-	-	-	-	-
HBBFKNIG_02233	2.07e-196	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HBBFKNIG_02234	3.96e-126	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HBBFKNIG_02235	9.52e-272	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HBBFKNIG_02236	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HBBFKNIG_02237	3.04e-36	ykoL	-	-	-	-	-	-	-
HBBFKNIG_02238	1.63e-25	-	-	-	-	-	-	-	-
HBBFKNIG_02239	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
HBBFKNIG_02240	9.44e-298	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HBBFKNIG_02242	1.45e-08	-	-	-	-	-	-	-	-
HBBFKNIG_02243	2.24e-112	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HBBFKNIG_02244	1.12e-144	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HBBFKNIG_02245	3.65e-308	ykoH	-	-	T	-	-	-	Histidine kinase
HBBFKNIG_02246	1.23e-158	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_02247	2.44e-142	ykoF	-	-	S	-	-	-	YKOF-related Family
HBBFKNIG_02248	5.67e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HBBFKNIG_02249	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_02250	1.81e-173	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HBBFKNIG_02251	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HBBFKNIG_02252	1.49e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HBBFKNIG_02253	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HBBFKNIG_02254	1.86e-125	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HBBFKNIG_02255	5.46e-113	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
HBBFKNIG_02256	2.34e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HBBFKNIG_02257	1.42e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HBBFKNIG_02258	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HBBFKNIG_02259	2.18e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HBBFKNIG_02260	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HBBFKNIG_02261	1.94e-216	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HBBFKNIG_02262	1.94e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HBBFKNIG_02263	7.34e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HBBFKNIG_02264	2e-125	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HBBFKNIG_02265	3.57e-125	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
HBBFKNIG_02266	2.67e-165	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HBBFKNIG_02267	3.55e-14	-	-	-	-	-	-	-	-
HBBFKNIG_02268	2.84e-284	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBBFKNIG_02269	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HBBFKNIG_02270	1.4e-202	ykgA	-	-	E	-	-	-	Amidinotransferase
HBBFKNIG_02271	6.64e-260	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HBBFKNIG_02272	1.03e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBBFKNIG_02273	2e-207	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HBBFKNIG_02274	2.68e-254	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HBBFKNIG_02275	7.89e-224	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HBBFKNIG_02277	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HBBFKNIG_02278	1.83e-234	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBBFKNIG_02279	3.02e-224	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBBFKNIG_02280	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBBFKNIG_02281	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HBBFKNIG_02282	1.93e-177	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
HBBFKNIG_02283	2.81e-283	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBBFKNIG_02285	7.41e-228	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HBBFKNIG_02286	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HBBFKNIG_02287	2.31e-232	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HBBFKNIG_02288	3.13e-310	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HBBFKNIG_02289	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HBBFKNIG_02290	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HBBFKNIG_02291	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HBBFKNIG_02292	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HBBFKNIG_02294	9.16e-209	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HBBFKNIG_02295	1.64e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
HBBFKNIG_02296	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HBBFKNIG_02297	2.31e-193	xepA	-	-	-	-	-	-	-
HBBFKNIG_02298	6.35e-31	xkdX	-	-	-	-	-	-	-
HBBFKNIG_02299	4.81e-55	xkdW	-	-	S	-	-	-	XkdW protein
HBBFKNIG_02300	0.0	-	-	-	-	-	-	-	-
HBBFKNIG_02301	2.11e-54	-	-	-	-	-	-	-	-
HBBFKNIG_02302	3.23e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HBBFKNIG_02303	2.54e-243	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HBBFKNIG_02304	1.33e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HBBFKNIG_02305	3.56e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HBBFKNIG_02306	2.7e-231	xkdQ	-	-	G	-	-	-	NLP P60 protein
HBBFKNIG_02307	2.82e-155	xkdP	-	-	S	-	-	-	Lysin motif
HBBFKNIG_02308	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HBBFKNIG_02309	3.34e-101	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HBBFKNIG_02310	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
HBBFKNIG_02311	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HBBFKNIG_02312	6.78e-100	xkdJ	-	-	-	-	-	-	-
HBBFKNIG_02313	6.82e-114	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HBBFKNIG_02314	4.29e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
HBBFKNIG_02315	9.44e-82	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HBBFKNIG_02316	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
HBBFKNIG_02317	5.71e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HBBFKNIG_02318	0.0	yqbA	-	-	S	-	-	-	portal protein
HBBFKNIG_02319	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HBBFKNIG_02320	6.8e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HBBFKNIG_02321	1.91e-108	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HBBFKNIG_02325	5.04e-151	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HBBFKNIG_02326	1.57e-199	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
HBBFKNIG_02328	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HBBFKNIG_02329	6e-142	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HBBFKNIG_02330	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
HBBFKNIG_02331	1.41e-141	yjqB	-	-	S	-	-	-	Pfam:DUF867
HBBFKNIG_02332	1.07e-77	yjqA	-	-	S	-	-	-	Bacterial PH domain
HBBFKNIG_02333	7.58e-218	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HBBFKNIG_02334	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
HBBFKNIG_02336	1.73e-271	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HBBFKNIG_02337	7.1e-313	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
HBBFKNIG_02338	6.65e-104	yjoA	-	-	S	-	-	-	DinB family
HBBFKNIG_02339	4.56e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HBBFKNIG_02340	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HBBFKNIG_02341	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HBBFKNIG_02342	4.02e-237	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HBBFKNIG_02343	1.37e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
HBBFKNIG_02344	2.6e-194	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBBFKNIG_02345	9.24e-272	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HBBFKNIG_02346	1.35e-238	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HBBFKNIG_02347	1.03e-241	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
HBBFKNIG_02348	4.34e-314	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
HBBFKNIG_02349	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HBBFKNIG_02350	3.56e-279	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HBBFKNIG_02351	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HBBFKNIG_02352	7.33e-120	yjlB	-	-	S	-	-	-	Cupin domain
HBBFKNIG_02353	2.99e-223	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HBBFKNIG_02354	7.36e-171	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HBBFKNIG_02355	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HBBFKNIG_02356	2.38e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HBBFKNIG_02357	1.11e-41	-	-	-	-	-	-	-	-
HBBFKNIG_02358	4.84e-277	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HBBFKNIG_02359	4.35e-282	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HBBFKNIG_02361	2.25e-127	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HBBFKNIG_02363	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HBBFKNIG_02364	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HBBFKNIG_02365	4.08e-132	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HBBFKNIG_02366	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HBBFKNIG_02367	4.54e-210	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HBBFKNIG_02368	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
HBBFKNIG_02369	5.87e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
HBBFKNIG_02370	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HBBFKNIG_02372	3.07e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HBBFKNIG_02373	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HBBFKNIG_02374	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HBBFKNIG_02375	6.82e-104	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBBFKNIG_02377	4.21e-116	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HBBFKNIG_02378	9.24e-76	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HBBFKNIG_02379	8.45e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HBBFKNIG_02380	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_02381	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HBBFKNIG_02382	7.54e-62	yjcN	-	-	-	-	-	-	-
HBBFKNIG_02383	5.19e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HBBFKNIG_02384	7.6e-87	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HBBFKNIG_02388	6.54e-25	-	-	-	-	-	-	-	-
HBBFKNIG_02389	3.78e-17	-	-	-	-	-	-	-	-
HBBFKNIG_02390	8e-52	-	-	-	-	-	-	-	-
HBBFKNIG_02391	2.27e-24	-	-	-	-	-	-	-	-
HBBFKNIG_02393	1.22e-272	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
HBBFKNIG_02394	7.44e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HBBFKNIG_02395	8.72e-279	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HBBFKNIG_02396	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HBBFKNIG_02397	4.5e-176	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HBBFKNIG_02398	2.43e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HBBFKNIG_02399	4.49e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBBFKNIG_02400	6.31e-51	-	-	-	-	-	-	-	-
HBBFKNIG_02401	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HBBFKNIG_02402	5.39e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HBBFKNIG_02405	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HBBFKNIG_02406	2.28e-69	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
HBBFKNIG_02407	1.34e-33	cotW	-	-	-	ko:K06341	-	ko00000	-
HBBFKNIG_02408	3.37e-101	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HBBFKNIG_02409	3.12e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HBBFKNIG_02410	3.92e-107	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HBBFKNIG_02411	9.87e-102	yjbX	-	-	S	-	-	-	Spore coat protein
HBBFKNIG_02412	1.75e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HBBFKNIG_02413	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HBBFKNIG_02414	2.41e-235	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HBBFKNIG_02415	2.76e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HBBFKNIG_02416	2.18e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
HBBFKNIG_02417	7.36e-274	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HBBFKNIG_02418	2.6e-135	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HBBFKNIG_02419	1.83e-173	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBBFKNIG_02420	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HBBFKNIG_02421	6.65e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HBBFKNIG_02422	2.12e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HBBFKNIG_02423	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBBFKNIG_02424	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HBBFKNIG_02425	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HBBFKNIG_02426	4.23e-129	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_02427	2.89e-125	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HBBFKNIG_02428	4.97e-93	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HBBFKNIG_02429	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBBFKNIG_02430	2.68e-28	-	-	-	-	-	-	-	-
HBBFKNIG_02431	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HBBFKNIG_02432	7.8e-276	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HBBFKNIG_02433	5.66e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HBBFKNIG_02434	2.03e-143	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HBBFKNIG_02435	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HBBFKNIG_02436	2.35e-129	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBBFKNIG_02437	1.94e-259	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HBBFKNIG_02438	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBBFKNIG_02439	3.92e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBBFKNIG_02440	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBBFKNIG_02441	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBBFKNIG_02442	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HBBFKNIG_02443	7.18e-234	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HBBFKNIG_02444	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HBBFKNIG_02445	4.25e-197	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBBFKNIG_02446	1.58e-214	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBBFKNIG_02447	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HBBFKNIG_02448	6.93e-236	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBBFKNIG_02449	1.76e-233	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBBFKNIG_02450	9.1e-191	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HBBFKNIG_02451	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HBBFKNIG_02452	4.6e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HBBFKNIG_02453	9.68e-34	yjzB	-	-	-	-	-	-	-
HBBFKNIG_02454	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HBBFKNIG_02455	3.7e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HBBFKNIG_02456	1.49e-131	yjaV	-	-	-	-	-	-	-
HBBFKNIG_02457	1.63e-180	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HBBFKNIG_02458	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HBBFKNIG_02459	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
HBBFKNIG_02460	4.27e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HBBFKNIG_02461	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HBBFKNIG_02462	9.47e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HBBFKNIG_02463	1.62e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HBBFKNIG_02464	1.27e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HBBFKNIG_02465	3.52e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HBBFKNIG_02466	2.38e-251	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HBBFKNIG_02467	1.95e-113	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HBBFKNIG_02468	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HBBFKNIG_02469	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
HBBFKNIG_02470	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HBBFKNIG_02471	1.19e-183	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HBBFKNIG_02472	6.18e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HBBFKNIG_02473	5.49e-08	-	-	-	-	-	-	-	-
HBBFKNIG_02474	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HBBFKNIG_02475	2.78e-93	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HBBFKNIG_02476	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBBFKNIG_02477	1.07e-200	yitS	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_02478	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HBBFKNIG_02479	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
HBBFKNIG_02480	6.11e-120	-	-	-	-	-	-	-	-
HBBFKNIG_02481	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HBBFKNIG_02482	3.84e-126	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
HBBFKNIG_02483	1.42e-218	-	-	-	-	-	-	-	-
HBBFKNIG_02484	1.69e-121	-	-	-	-	-	-	-	-
HBBFKNIG_02485	2.75e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HBBFKNIG_02486	2.73e-55	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HBBFKNIG_02487	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HBBFKNIG_02488	1.46e-91	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HBBFKNIG_02489	1.57e-197	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HBBFKNIG_02490	4.1e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_02491	2.91e-281	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HBBFKNIG_02492	6.62e-140	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBBFKNIG_02493	1.75e-179	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
HBBFKNIG_02494	9.32e-154	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
HBBFKNIG_02495	2.07e-179	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HBBFKNIG_02496	3.78e-293	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HBBFKNIG_02497	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HBBFKNIG_02498	4.53e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HBBFKNIG_02499	1.76e-95	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HBBFKNIG_02500	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBBFKNIG_02501	1.05e-137	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HBBFKNIG_02502	4.05e-119	yisT	-	-	S	-	-	-	DinB family
HBBFKNIG_02503	1.12e-243	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HBBFKNIG_02504	6.13e-234	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HBBFKNIG_02505	2e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_02506	2.91e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
HBBFKNIG_02507	4.02e-151	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HBBFKNIG_02508	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HBBFKNIG_02509	9.03e-133	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HBBFKNIG_02510	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HBBFKNIG_02511	1.44e-74	yisL	-	-	S	-	-	-	UPF0344 protein
HBBFKNIG_02512	3.78e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HBBFKNIG_02513	1.09e-221	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HBBFKNIG_02514	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HBBFKNIG_02515	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HBBFKNIG_02516	3.87e-42	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HBBFKNIG_02517	3.34e-92	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HBBFKNIG_02518	1.49e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HBBFKNIG_02519	3.92e-86	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HBBFKNIG_02520	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HBBFKNIG_02521	4.51e-65	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HBBFKNIG_02522	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HBBFKNIG_02523	8.08e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HBBFKNIG_02524	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HBBFKNIG_02525	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HBBFKNIG_02526	2.19e-100	yhjR	-	-	S	-	-	-	Rubrerythrin
HBBFKNIG_02527	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
HBBFKNIG_02528	1.58e-266	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HBBFKNIG_02529	1.02e-258	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HBBFKNIG_02531	2.52e-238	yhjM	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_02532	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HBBFKNIG_02533	5.09e-203	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
HBBFKNIG_02534	1.14e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HBBFKNIG_02535	4.95e-270	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HBBFKNIG_02536	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBBFKNIG_02537	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HBBFKNIG_02538	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HBBFKNIG_02539	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HBBFKNIG_02540	5.65e-76	yhjD	-	-	-	-	-	-	-
HBBFKNIG_02541	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HBBFKNIG_02542	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBBFKNIG_02543	6.6e-53	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HBBFKNIG_02544	8.54e-215	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HBBFKNIG_02545	1.27e-140	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HBBFKNIG_02546	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
HBBFKNIG_02547	6.43e-203	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBBFKNIG_02548	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HBBFKNIG_02549	1.76e-258	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HBBFKNIG_02550	2.97e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HBBFKNIG_02551	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HBBFKNIG_02552	3.49e-249	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HBBFKNIG_02553	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HBBFKNIG_02554	6.25e-220	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HBBFKNIG_02555	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HBBFKNIG_02556	1.49e-61	-	-	-	K	-	-	-	acetyltransferase
HBBFKNIG_02557	2.81e-259	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HBBFKNIG_02558	1.47e-302	yhfN	-	-	O	-	-	-	Peptidase M48
HBBFKNIG_02559	1.13e-84	yhfM	-	-	-	-	-	-	-
HBBFKNIG_02560	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HBBFKNIG_02561	6.1e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
HBBFKNIG_02562	4.06e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HBBFKNIG_02563	6.93e-182	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HBBFKNIG_02564	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBBFKNIG_02565	5.12e-92	-	-	-	S	-	-	-	ASCH
HBBFKNIG_02566	4.44e-252	yhfE	-	-	G	-	-	-	peptidase M42
HBBFKNIG_02567	1.88e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
HBBFKNIG_02568	2.51e-236	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HBBFKNIG_02569	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HBBFKNIG_02570	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_02571	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HBBFKNIG_02572	3.41e-231	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HBBFKNIG_02573	5.25e-259	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HBBFKNIG_02574	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HBBFKNIG_02575	6.25e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HBBFKNIG_02576	4.07e-44	-	-	-	C	-	-	-	Rubrerythrin
HBBFKNIG_02577	5.44e-312	yhfA	-	-	C	-	-	-	membrane
HBBFKNIG_02578	1.48e-289	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HBBFKNIG_02579	1.37e-159	ecsC	-	-	S	-	-	-	EcsC protein family
HBBFKNIG_02580	1.48e-270	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HBBFKNIG_02581	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HBBFKNIG_02582	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HBBFKNIG_02583	3.57e-260	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HBBFKNIG_02584	3e-102	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HBBFKNIG_02585	9.66e-30	-	-	-	-	-	-	-	-
HBBFKNIG_02586	3.89e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
HBBFKNIG_02587	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HBBFKNIG_02588	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HBBFKNIG_02589	8.11e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HBBFKNIG_02590	7.65e-178	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HBBFKNIG_02591	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HBBFKNIG_02592	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HBBFKNIG_02593	0.0	yhaN	-	-	L	-	-	-	AAA domain
HBBFKNIG_02594	2.38e-294	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HBBFKNIG_02595	1.47e-271	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HBBFKNIG_02596	3.22e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_02597	2.29e-36	-	-	-	S	-	-	-	YhzD-like protein
HBBFKNIG_02598	5.65e-168	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HBBFKNIG_02600	1.87e-113	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HBBFKNIG_02601	8.4e-264	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HBBFKNIG_02602	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HBBFKNIG_02603	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HBBFKNIG_02604	1.24e-259	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
HBBFKNIG_02605	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HBBFKNIG_02606	5.65e-257	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HBBFKNIG_02607	9.67e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HBBFKNIG_02608	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HBBFKNIG_02610	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HBBFKNIG_02611	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HBBFKNIG_02612	2.15e-139	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HBBFKNIG_02613	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HBBFKNIG_02614	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HBBFKNIG_02616	3.69e-107	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
HBBFKNIG_02617	5.97e-302	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HBBFKNIG_02618	9.07e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HBBFKNIG_02619	3.03e-195	nodB1	-	-	G	-	-	-	deacetylase
HBBFKNIG_02620	1.14e-177	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HBBFKNIG_02621	9.73e-239	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HBBFKNIG_02622	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HBBFKNIG_02623	7.42e-172	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HBBFKNIG_02624	2.78e-85	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBBFKNIG_02625	1.18e-64	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBBFKNIG_02626	4.33e-315	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HBBFKNIG_02627	5.1e-284	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HBBFKNIG_02628	2.83e-96	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HBBFKNIG_02629	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HBBFKNIG_02630	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HBBFKNIG_02631	5.54e-243	yhdN	-	-	C	-	-	-	Aldo keto reductase
HBBFKNIG_02632	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBBFKNIG_02633	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HBBFKNIG_02634	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HBBFKNIG_02635	7.13e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBBFKNIG_02636	4.52e-195	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBBFKNIG_02637	1.71e-130	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBBFKNIG_02638	2.48e-309	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HBBFKNIG_02639	1.43e-315	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HBBFKNIG_02640	1.92e-206	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBBFKNIG_02641	1.3e-261	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HBBFKNIG_02642	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_02643	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HBBFKNIG_02644	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HBBFKNIG_02645	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HBBFKNIG_02646	2.38e-303	ygxB	-	-	M	-	-	-	Conserved TM helix
HBBFKNIG_02647	9.18e-252	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
HBBFKNIG_02648	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HBBFKNIG_02649	8.85e-271	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HBBFKNIG_02650	1.02e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HBBFKNIG_02651	1.36e-50	yhdB	-	-	S	-	-	-	YhdB-like protein
HBBFKNIG_02652	5.24e-113	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HBBFKNIG_02653	1.56e-143	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBBFKNIG_02654	6.28e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_02655	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HBBFKNIG_02656	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HBBFKNIG_02657	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBBFKNIG_02658	2.32e-195	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HBBFKNIG_02659	6.25e-134	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HBBFKNIG_02660	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBBFKNIG_02661	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HBBFKNIG_02662	8.37e-153	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HBBFKNIG_02663	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HBBFKNIG_02664	2.89e-87	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HBBFKNIG_02665	2.76e-217	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HBBFKNIG_02666	6.2e-135	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HBBFKNIG_02667	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HBBFKNIG_02668	1.68e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
HBBFKNIG_02669	3.12e-224	yhcP	-	-	-	-	-	-	-
HBBFKNIG_02670	7.71e-111	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HBBFKNIG_02671	1.69e-72	yhcM	-	-	-	-	-	-	-
HBBFKNIG_02672	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBBFKNIG_02673	2.88e-250	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HBBFKNIG_02674	4.31e-192	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HBBFKNIG_02675	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HBBFKNIG_02676	1.4e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HBBFKNIG_02677	7.55e-212	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_02678	5.38e-155	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_02679	4.78e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_02680	6.7e-68	-	-	-	-	-	-	-	-
HBBFKNIG_02681	1.08e-56	yhcC	-	-	-	-	-	-	-
HBBFKNIG_02682	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
HBBFKNIG_02683	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HBBFKNIG_02684	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HBBFKNIG_02685	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HBBFKNIG_02686	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HBBFKNIG_02687	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HBBFKNIG_02688	1.42e-103	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HBBFKNIG_02689	4.62e-96	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HBBFKNIG_02690	7.67e-140	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HBBFKNIG_02691	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HBBFKNIG_02692	6.53e-224	yhbB	-	-	S	-	-	-	Putative amidase domain
HBBFKNIG_02693	2.82e-282	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HBBFKNIG_02694	4.87e-141	yhzB	-	-	S	-	-	-	B3/4 domain
HBBFKNIG_02696	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_02697	6.58e-101	ygaO	-	-	-	-	-	-	-
HBBFKNIG_02698	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HBBFKNIG_02699	2.57e-273	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HBBFKNIG_02700	9.72e-189	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HBBFKNIG_02701	1.4e-216	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HBBFKNIG_02702	2.92e-185	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HBBFKNIG_02703	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HBBFKNIG_02705	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HBBFKNIG_02707	5.27e-168	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HBBFKNIG_02708	1.58e-36	-	-	-	-	-	-	-	-
HBBFKNIG_02709	9.06e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
HBBFKNIG_02726	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBBFKNIG_02727	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HBBFKNIG_02728	3.38e-73	ygzB	-	-	S	-	-	-	UPF0295 protein
HBBFKNIG_02729	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HBBFKNIG_02730	6.88e-112	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HBBFKNIG_02731	2.2e-310	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HBBFKNIG_02732	2.54e-236	ygaE	-	-	S	-	-	-	Membrane
HBBFKNIG_02733	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HBBFKNIG_02734	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HBBFKNIG_02735	1.88e-63	ygaB	-	-	S	-	-	-	YgaB-like protein
HBBFKNIG_02736	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HBBFKNIG_02737	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBBFKNIG_02738	1.73e-48	yfhS	-	-	-	-	-	-	-
HBBFKNIG_02739	2.16e-264	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HBBFKNIG_02740	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HBBFKNIG_02741	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HBBFKNIG_02742	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HBBFKNIG_02743	7.62e-216	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
HBBFKNIG_02744	5.4e-67	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HBBFKNIG_02745	1.91e-114	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HBBFKNIG_02746	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
HBBFKNIG_02747	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
HBBFKNIG_02748	8.17e-267	yfhI	-	-	EGP	-	-	-	-transporter
HBBFKNIG_02750	3.11e-67	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HBBFKNIG_02751	1.22e-178	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HBBFKNIG_02752	4.42e-219	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HBBFKNIG_02754	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
HBBFKNIG_02755	3.91e-136	yfhC	-	-	C	-	-	-	nitroreductase
HBBFKNIG_02756	1.41e-210	yfhB	-	-	S	-	-	-	PhzF family
HBBFKNIG_02757	5.18e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_02758	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_02759	3.83e-231	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HBBFKNIG_02760	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HBBFKNIG_02761	8.59e-103	yfiV	-	-	K	-	-	-	transcriptional
HBBFKNIG_02762	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HBBFKNIG_02763	7.75e-126	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HBBFKNIG_02764	5.72e-268	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
HBBFKNIG_02765	3.03e-134	yfiR	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_02766	1.77e-241	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HBBFKNIG_02767	2.11e-98	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HBBFKNIG_02768	6.35e-111	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HBBFKNIG_02769	6.94e-76	-	-	-	GM	-	-	-	NADH-flavin reductase
HBBFKNIG_02770	9.72e-84	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HBBFKNIG_02771	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HBBFKNIG_02772	3.14e-127	padR	-	-	K	-	-	-	transcriptional
HBBFKNIG_02773	1.47e-85	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HBBFKNIG_02774	1.28e-257	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HBBFKNIG_02775	3.43e-263	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HBBFKNIG_02776	2.42e-211	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_02777	3.37e-143	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HBBFKNIG_02778	1.97e-238	baeS	-	-	T	-	-	-	Histidine kinase
HBBFKNIG_02779	6.99e-207	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HBBFKNIG_02780	3.34e-83	yfiD3	-	-	S	-	-	-	DoxX
HBBFKNIG_02781	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HBBFKNIG_02782	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HBBFKNIG_02783	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_02784	3.03e-181	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HBBFKNIG_02785	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HBBFKNIG_02786	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
HBBFKNIG_02787	5.56e-270	yfjB	-	-	-	-	-	-	-
HBBFKNIG_02788	1.45e-184	yfjC	-	-	-	-	-	-	-
HBBFKNIG_02789	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
HBBFKNIG_02790	1.05e-74	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
HBBFKNIG_02791	2.26e-33	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HBBFKNIG_02792	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HBBFKNIG_02793	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HBBFKNIG_02794	1.28e-259	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HBBFKNIG_02795	4.56e-243	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HBBFKNIG_02796	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HBBFKNIG_02798	2.25e-109	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HBBFKNIG_02799	1.77e-236	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBBFKNIG_02800	8.71e-59	-	-	-	S	-	-	-	YfzA-like protein
HBBFKNIG_02801	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBBFKNIG_02802	1.94e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HBBFKNIG_02803	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HBBFKNIG_02804	1.88e-191	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HBBFKNIG_02805	1.71e-196	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HBBFKNIG_02806	3.26e-36	yfjT	-	-	-	-	-	-	-
HBBFKNIG_02807	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
HBBFKNIG_02808	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HBBFKNIG_02809	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
HBBFKNIG_02810	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HBBFKNIG_02811	2.22e-277	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_02812	1.64e-12	-	-	-	-	-	-	-	-
HBBFKNIG_02813	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HBBFKNIG_02814	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
HBBFKNIG_02815	4.15e-108	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBBFKNIG_02816	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HBBFKNIG_02817	5.72e-263	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_02818	3.7e-112	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HBBFKNIG_02819	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HBBFKNIG_02820	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
HBBFKNIG_02821	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HBBFKNIG_02822	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HBBFKNIG_02823	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_02824	0.0	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
HBBFKNIG_02825	1.08e-269	yfkR	-	-	S	ko:K06297,ko:K06308	-	ko00000	spore germination
HBBFKNIG_02827	4.42e-249	yfkT	-	-	E	ko:K06309	-	ko00000	Spore germination protein
HBBFKNIG_02828	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HBBFKNIG_02829	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HBBFKNIG_02830	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HBBFKNIG_02831	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HBBFKNIG_02832	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HBBFKNIG_02833	2.1e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HBBFKNIG_02834	6.9e-27	yflI	-	-	-	-	-	-	-
HBBFKNIG_02835	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HBBFKNIG_02836	3.42e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_02837	4.94e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HBBFKNIG_02838	3.94e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HBBFKNIG_02839	1.7e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HBBFKNIG_02840	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HBBFKNIG_02841	9e-227	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HBBFKNIG_02842	1.61e-153	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HBBFKNIG_02843	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HBBFKNIG_02844	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HBBFKNIG_02845	1.42e-306	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HBBFKNIG_02846	6.96e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HBBFKNIG_02847	1.5e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HBBFKNIG_02848	7.91e-219	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HBBFKNIG_02849	4.72e-220	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_02850	2.1e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_02851	5.69e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HBBFKNIG_02852	1.92e-238	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HBBFKNIG_02853	2.44e-94	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
HBBFKNIG_02854	7.25e-264	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HBBFKNIG_02855	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HBBFKNIG_02856	3.63e-95	-	-	-	-	-	-	-	-
HBBFKNIG_02857	6.88e-11	yhfO	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBBFKNIG_02858	2.95e-264	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HBBFKNIG_02859	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HBBFKNIG_02860	9.21e-99	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HBBFKNIG_02861	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HBBFKNIG_02862	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
HBBFKNIG_02863	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HBBFKNIG_02864	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HBBFKNIG_02865	1.56e-169	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HBBFKNIG_02866	5.94e-266	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_02867	3.88e-242	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HBBFKNIG_02868	5.74e-285	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HBBFKNIG_02869	1.62e-230	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HBBFKNIG_02870	1.37e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HBBFKNIG_02871	8.42e-188	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HBBFKNIG_02872	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HBBFKNIG_02873	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HBBFKNIG_02874	1.75e-254	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HBBFKNIG_02875	9.13e-50	yetM	-	-	CH	-	-	-	FAD binding domain
HBBFKNIG_02876	2.55e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HBBFKNIG_02877	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HBBFKNIG_02878	3.59e-184	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HBBFKNIG_02879	1.29e-44	-	-	-	-	-	-	-	-
HBBFKNIG_02880	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBBFKNIG_02881	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HBBFKNIG_02882	3.66e-157	yetF	-	-	S	-	-	-	membrane
HBBFKNIG_02883	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HBBFKNIG_02884	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBBFKNIG_02885	2.78e-225	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HBBFKNIG_02886	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HBBFKNIG_02887	0.0	yetA	-	-	-	-	-	-	-
HBBFKNIG_02888	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HBBFKNIG_02889	2.15e-158	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HBBFKNIG_02890	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HBBFKNIG_02891	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HBBFKNIG_02892	1.64e-144	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HBBFKNIG_02893	7.52e-165	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
HBBFKNIG_02894	1.9e-166	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HBBFKNIG_02895	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_02896	3.26e-253	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HBBFKNIG_02897	3.08e-211	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBBFKNIG_02898	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBBFKNIG_02899	1.68e-313	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HBBFKNIG_02900	3.27e-256	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HBBFKNIG_02901	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_02902	2.86e-129	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
HBBFKNIG_02904	4.15e-131	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HBBFKNIG_02905	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HBBFKNIG_02906	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HBBFKNIG_02907	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HBBFKNIG_02908	1.04e-189	yesF	-	-	GM	-	-	-	NAD(P)H-binding
HBBFKNIG_02909	8.24e-104	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
HBBFKNIG_02910	6.99e-130	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_02912	1.09e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HBBFKNIG_02914	2.26e-267	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
HBBFKNIG_02915	2.28e-14	-	-	-	S	-	-	-	Pfam:DUF1311
HBBFKNIG_02916	1.4e-126	-	-	-	L	-	-	-	endonuclease activity
HBBFKNIG_02918	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
HBBFKNIG_02919	2.11e-108	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HBBFKNIG_02920	8.07e-49	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HBBFKNIG_02922	2.92e-35	-	-	-	-	-	-	-	-
HBBFKNIG_02924	1.91e-67	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	Domain of unknown function (DUF3578)
HBBFKNIG_02925	6.88e-146	-	-	-	-	-	-	-	-
HBBFKNIG_02926	4.64e-159	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
HBBFKNIG_02927	3.89e-24	-	-	-	-	-	-	-	-
HBBFKNIG_02928	2.04e-39	-	-	-	K	-	-	-	Wd-40 repeat
HBBFKNIG_02929	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBBFKNIG_02930	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HBBFKNIG_02931	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBBFKNIG_02932	1.26e-191	yerO	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_02933	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBBFKNIG_02934	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HBBFKNIG_02935	2.11e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBBFKNIG_02936	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBBFKNIG_02937	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HBBFKNIG_02938	1.22e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HBBFKNIG_02939	1.45e-280	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HBBFKNIG_02940	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HBBFKNIG_02941	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HBBFKNIG_02942	6.11e-159	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HBBFKNIG_02944	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HBBFKNIG_02945	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_02946	1.12e-242	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HBBFKNIG_02947	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HBBFKNIG_02948	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HBBFKNIG_02949	1.6e-289	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
HBBFKNIG_02950	6.15e-95	-	-	-	K	-	-	-	helix_turn_helix ASNC type
HBBFKNIG_02951	9.43e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HBBFKNIG_02952	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HBBFKNIG_02953	2.55e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBBFKNIG_02954	4.02e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HBBFKNIG_02955	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HBBFKNIG_02956	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBBFKNIG_02957	1.91e-166	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBBFKNIG_02958	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBBFKNIG_02959	3.39e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HBBFKNIG_02960	2.81e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBBFKNIG_02961	1.74e-273	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBBFKNIG_02962	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HBBFKNIG_02963	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
HBBFKNIG_02964	1.08e-119	yebE	-	-	S	-	-	-	UPF0316 protein
HBBFKNIG_02966	4.8e-164	yebC	-	-	M	-	-	-	Membrane
HBBFKNIG_02967	2.68e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HBBFKNIG_02968	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
HBBFKNIG_02969	1.33e-112	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBBFKNIG_02970	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HBBFKNIG_02971	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HBBFKNIG_02972	4.55e-285	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HBBFKNIG_02973	6.29e-223	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HBBFKNIG_02974	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBBFKNIG_02975	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HBBFKNIG_02976	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HBBFKNIG_02977	2.78e-226	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
HBBFKNIG_02978	1.4e-197	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HBBFKNIG_02979	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HBBFKNIG_02981	8.06e-208	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HBBFKNIG_02982	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
HBBFKNIG_02983	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HBBFKNIG_02984	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBBFKNIG_02985	1.37e-248	-	-	-	S	-	-	-	Ion transport 2 domain protein
HBBFKNIG_02986	1.64e-199	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HBBFKNIG_02987	3.65e-173	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HBBFKNIG_02988	3.49e-226	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBBFKNIG_02989	1.79e-146	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HBBFKNIG_02990	3.59e-217	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HBBFKNIG_02991	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HBBFKNIG_02992	1.24e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HBBFKNIG_02993	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HBBFKNIG_02994	1.89e-193	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
HBBFKNIG_02995	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HBBFKNIG_02996	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HBBFKNIG_02997	1.43e-165	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HBBFKNIG_02998	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HBBFKNIG_02999	8.73e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HBBFKNIG_03000	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HBBFKNIG_03001	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HBBFKNIG_03002	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HBBFKNIG_03003	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HBBFKNIG_03004	4.48e-239	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HBBFKNIG_03005	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HBBFKNIG_03006	1.19e-161	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HBBFKNIG_03007	7.42e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HBBFKNIG_03008	3.83e-231	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HBBFKNIG_03011	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBBFKNIG_03014	4.89e-202	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HBBFKNIG_03015	2.17e-267	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HBBFKNIG_03016	3.44e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HBBFKNIG_03017	6.73e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HBBFKNIG_03018	1.44e-166	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HBBFKNIG_03019	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HBBFKNIG_03020	1.31e-304	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBBFKNIG_03021	1.97e-66	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_03022	1.88e-63	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_03023	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HBBFKNIG_03024	9.05e-127	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HBBFKNIG_03025	2.7e-231	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HBBFKNIG_03026	1.8e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HBBFKNIG_03028	3.75e-86	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HBBFKNIG_03029	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HBBFKNIG_03030	2.04e-161	-	-	-	-	-	-	-	-
HBBFKNIG_03031	4.57e-288	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HBBFKNIG_03032	1.93e-304	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HBBFKNIG_03033	5.87e-155	ydhC	-	-	K	-	-	-	FCD
HBBFKNIG_03034	1.45e-154	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HBBFKNIG_03035	4.02e-265	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HBBFKNIG_03036	1.9e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HBBFKNIG_03037	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
HBBFKNIG_03038	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HBBFKNIG_03039	1.99e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBBFKNIG_03040	8.11e-116	-	-	-	S	-	-	-	DinB family
HBBFKNIG_03041	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HBBFKNIG_03042	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HBBFKNIG_03043	1.48e-63	-	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03044	1.52e-176	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_03045	9.77e-62	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
HBBFKNIG_03046	1.39e-111	yycN	-	-	K	-	-	-	Acetyltransferase
HBBFKNIG_03047	8.18e-70	-	-	-	S	-	-	-	DoxX-like family
HBBFKNIG_03048	4.92e-127	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HBBFKNIG_03049	4.99e-44	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HBBFKNIG_03050	1.53e-47	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HBBFKNIG_03051	8.6e-88	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HBBFKNIG_03052	1.25e-109	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HBBFKNIG_03053	2.44e-141	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
HBBFKNIG_03055	7.9e-41	-	-	-	-	-	-	-	-
HBBFKNIG_03056	1.69e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HBBFKNIG_03057	2.27e-75	ydfQ	-	-	CO	-	-	-	Thioredoxin
HBBFKNIG_03058	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
HBBFKNIG_03059	1.29e-236	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HBBFKNIG_03060	1.91e-142	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
HBBFKNIG_03061	8.64e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBBFKNIG_03062	1.44e-187	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HBBFKNIG_03063	2.65e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HBBFKNIG_03064	1.27e-221	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HBBFKNIG_03065	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
HBBFKNIG_03066	1.33e-141	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBBFKNIG_03067	5.86e-249	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_03069	7.91e-104	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBBFKNIG_03070	3.54e-157	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HBBFKNIG_03071	1.35e-147	ydfE	-	-	S	-	-	-	Flavin reductase like domain
HBBFKNIG_03072	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBBFKNIG_03073	6.88e-191	-	-	-	EG	-	-	-	EamA-like transporter family
HBBFKNIG_03074	2.25e-156	-	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HBBFKNIG_03075	3.09e-278	-	-	-	T	-	-	-	GHKL domain
HBBFKNIG_03076	6.2e-200	-	-	-	-	-	-	-	-
HBBFKNIG_03077	5.91e-157	nodB1	-	-	G	-	-	-	deacetylase
HBBFKNIG_03078	1.08e-187	-	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03079	1.49e-182	-	-	-	J	-	-	-	GNAT acetyltransferase
HBBFKNIG_03080	5.02e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBBFKNIG_03081	1.05e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HBBFKNIG_03083	2.16e-135	ydeS	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03084	1.08e-254	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HBBFKNIG_03085	4.07e-144	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
HBBFKNIG_03086	5.03e-91	ydeP	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03087	1.48e-190	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBBFKNIG_03088	7.15e-73	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HBBFKNIG_03089	5.36e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HBBFKNIG_03090	3.68e-97	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HBBFKNIG_03091	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBBFKNIG_03092	7.4e-194	ydeK	-	-	EG	-	-	-	-transporter
HBBFKNIG_03093	7.04e-140	-	-	-	-	-	-	-	-
HBBFKNIG_03094	9.93e-136	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HBBFKNIG_03095	3.74e-69	ydeH	-	-	-	-	-	-	-
HBBFKNIG_03096	2.31e-268	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
HBBFKNIG_03097	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBBFKNIG_03098	2.64e-209	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HBBFKNIG_03099	5.97e-216	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HBBFKNIG_03100	1.12e-207	-	-	-	K	-	-	-	AraC-like ligand binding domain
HBBFKNIG_03101	8.42e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
HBBFKNIG_03102	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HBBFKNIG_03103	1.42e-246	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HBBFKNIG_03104	1.72e-52	-	-	-	-	-	-	-	-
HBBFKNIG_03105	1.8e-45	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HBBFKNIG_03106	9.03e-14	-	-	-	E	ko:K07032	-	ko00000	PFAM Glyoxalase bleomycin resistance protein dioxygenase
HBBFKNIG_03107	8.6e-61	ydeH	-	-	-	-	-	-	-
HBBFKNIG_03108	1.57e-258	abcA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HBBFKNIG_03109	5.14e-268	-	-	-	KLT	-	-	-	Protein kinase domain
HBBFKNIG_03116	1.72e-187	-	-	-	KLT	-	-	-	Protein kinase domain
HBBFKNIG_03127	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HBBFKNIG_03128	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HBBFKNIG_03129	1.48e-99	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBBFKNIG_03130	1.32e-106	ydcG	-	-	S	-	-	-	EVE domain
HBBFKNIG_03132	2.17e-140	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HBBFKNIG_03133	3.12e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBBFKNIG_03134	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HBBFKNIG_03135	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HBBFKNIG_03136	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HBBFKNIG_03137	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HBBFKNIG_03138	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HBBFKNIG_03139	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HBBFKNIG_03140	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HBBFKNIG_03141	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HBBFKNIG_03142	1.19e-280	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBBFKNIG_03143	9.41e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HBBFKNIG_03144	1.6e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HBBFKNIG_03145	2.08e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HBBFKNIG_03146	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HBBFKNIG_03147	7.1e-106	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HBBFKNIG_03148	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HBBFKNIG_03149	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HBBFKNIG_03150	3.58e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HBBFKNIG_03151	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
HBBFKNIG_03152	4.5e-201	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBBFKNIG_03153	2.1e-11	-	-	-	S	-	-	-	Fur-regulated basic protein A
HBBFKNIG_03154	8.64e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
HBBFKNIG_03155	3.54e-278	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HBBFKNIG_03156	9.32e-70	ydbL	-	-	-	-	-	-	-
HBBFKNIG_03157	1.22e-158	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HBBFKNIG_03158	1.08e-217	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_03159	3.25e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
HBBFKNIG_03160	8.93e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBBFKNIG_03161	2.79e-154	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HBBFKNIG_03162	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HBBFKNIG_03163	6.07e-252	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HBBFKNIG_03164	9.11e-197	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HBBFKNIG_03165	8.65e-81	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HBBFKNIG_03166	1.07e-75	ydbB	-	-	G	-	-	-	Cupin domain
HBBFKNIG_03167	3.3e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HBBFKNIG_03168	2.05e-188	ydbA	-	-	P	-	-	-	EcsC protein family
HBBFKNIG_03169	3.73e-99	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HBBFKNIG_03170	1.67e-42	ydaS	-	-	S	-	-	-	membrane
HBBFKNIG_03171	5.54e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HBBFKNIG_03172	2.14e-53	-	-	-	-	-	-	-	-
HBBFKNIG_03173	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HBBFKNIG_03174	6.23e-100	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HBBFKNIG_03175	0.0	ydaO	-	-	E	-	-	-	amino acid
HBBFKNIG_03176	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HBBFKNIG_03177	1.93e-304	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HBBFKNIG_03178	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HBBFKNIG_03179	1.49e-191	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HBBFKNIG_03180	9.49e-262	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HBBFKNIG_03181	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HBBFKNIG_03182	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HBBFKNIG_03183	3.12e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HBBFKNIG_03184	1.31e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HBBFKNIG_03185	4.32e-100	ydaG	-	-	S	-	-	-	general stress protein
HBBFKNIG_03186	4.44e-123	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HBBFKNIG_03187	5.56e-125	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HBBFKNIG_03188	6.21e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBBFKNIG_03189	1.43e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
HBBFKNIG_03190	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HBBFKNIG_03191	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HBBFKNIG_03192	4.09e-218	ycsN	-	-	S	-	-	-	Oxidoreductase
HBBFKNIG_03193	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HBBFKNIG_03194	7.67e-66	yczJ	-	-	S	-	-	-	biosynthesis
HBBFKNIG_03196	9.02e-148	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HBBFKNIG_03197	3.64e-169	kipR	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03198	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HBBFKNIG_03199	1.97e-170	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HBBFKNIG_03200	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HBBFKNIG_03201	2.78e-273	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HBBFKNIG_03202	2.12e-178	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HBBFKNIG_03203	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HBBFKNIG_03205	9.34e-88	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HBBFKNIG_03206	9.14e-139	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
HBBFKNIG_03207	3.44e-94	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HBBFKNIG_03209	2.05e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HBBFKNIG_03210	2.97e-266	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HBBFKNIG_03211	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HBBFKNIG_03212	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HBBFKNIG_03213	1.34e-74	-	-	-	-	-	-	-	-
HBBFKNIG_03214	8.26e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HBBFKNIG_03215	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HBBFKNIG_03216	1.9e-132	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_03217	2.69e-183	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBBFKNIG_03218	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HBBFKNIG_03219	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HBBFKNIG_03220	6.31e-309	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBBFKNIG_03221	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBBFKNIG_03222	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HBBFKNIG_03223	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
HBBFKNIG_03224	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HBBFKNIG_03225	1.68e-197	ycnC	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03226	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HBBFKNIG_03227	1.64e-212	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HBBFKNIG_03228	5.63e-176	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_03229	3.16e-209	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_03230	2.2e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_03231	1.8e-292	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HBBFKNIG_03232	7.93e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HBBFKNIG_03234	2.18e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HBBFKNIG_03235	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HBBFKNIG_03236	6.39e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_03237	6.2e-277	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HBBFKNIG_03238	4.82e-155	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HBBFKNIG_03239	1.36e-246	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HBBFKNIG_03240	3.9e-286	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HBBFKNIG_03241	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
HBBFKNIG_03243	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HBBFKNIG_03244	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HBBFKNIG_03245	1.58e-201	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
HBBFKNIG_03246	1.7e-106	yclD	-	-	-	-	-	-	-
HBBFKNIG_03247	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
HBBFKNIG_03248	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HBBFKNIG_03249	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HBBFKNIG_03250	5.32e-209	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HBBFKNIG_03251	3.03e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HBBFKNIG_03252	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HBBFKNIG_03253	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HBBFKNIG_03254	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HBBFKNIG_03255	4.57e-143	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HBBFKNIG_03256	9.36e-317	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
HBBFKNIG_03257	4.64e-205	ycxC	-	-	EG	-	-	-	EamA-like transporter family
HBBFKNIG_03258	8.93e-124	-	-	-	S	-	-	-	YcxB-like protein
HBBFKNIG_03259	1.04e-286	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HBBFKNIG_03260	1.29e-176	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HBBFKNIG_03261	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HBBFKNIG_03262	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBBFKNIG_03263	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBBFKNIG_03264	8.6e-86	hxlR	-	-	K	-	-	-	transcriptional
HBBFKNIG_03265	1.97e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HBBFKNIG_03266	3.64e-123	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HBBFKNIG_03267	1.76e-266	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBBFKNIG_03268	7.94e-100	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HBBFKNIG_03269	6.53e-89	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HBBFKNIG_03270	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HBBFKNIG_03271	1.01e-68	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HBBFKNIG_03272	1.91e-82	yckC	-	-	S	-	-	-	membrane
HBBFKNIG_03274	1.26e-185	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HBBFKNIG_03275	4.96e-148	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HBBFKNIG_03276	7.59e-288	yciC	-	-	S	-	-	-	GTPases (G3E family)
HBBFKNIG_03277	2.99e-140	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HBBFKNIG_03278	2.88e-220	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
HBBFKNIG_03279	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HBBFKNIG_03280	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
HBBFKNIG_03281	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBBFKNIG_03282	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBBFKNIG_03283	3.45e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HBBFKNIG_03284	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HBBFKNIG_03285	5.52e-241	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HBBFKNIG_03286	1.99e-201	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
HBBFKNIG_03287	6.16e-185	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
HBBFKNIG_03288	1.82e-193	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
HBBFKNIG_03289	3.22e-287	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HBBFKNIG_03290	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBBFKNIG_03291	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HBBFKNIG_03292	2.99e-217	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HBBFKNIG_03293	5.24e-185	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HBBFKNIG_03294	4.48e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HBBFKNIG_03295	7.67e-226	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
HBBFKNIG_03296	1.98e-181	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HBBFKNIG_03297	4.28e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HBBFKNIG_03299	2.09e-137	tmrB	-	-	S	-	-	-	AAA domain
HBBFKNIG_03300	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HBBFKNIG_03301	1.26e-143	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HBBFKNIG_03302	5.5e-315	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HBBFKNIG_03303	3.86e-188	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HBBFKNIG_03304	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HBBFKNIG_03305	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBBFKNIG_03306	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HBBFKNIG_03307	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HBBFKNIG_03308	1.62e-230	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HBBFKNIG_03309	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
HBBFKNIG_03310	2.72e-105	ycgB	-	-	-	-	-	-	-
HBBFKNIG_03311	0.0	ycgA	-	-	S	-	-	-	Membrane
HBBFKNIG_03312	1.48e-271	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HBBFKNIG_03313	5.76e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HBBFKNIG_03314	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HBBFKNIG_03315	1.66e-288	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HBBFKNIG_03316	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HBBFKNIG_03317	8.39e-261	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HBBFKNIG_03318	2.7e-278	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HBBFKNIG_03319	8.49e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
HBBFKNIG_03320	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HBBFKNIG_03321	4.1e-176	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HBBFKNIG_03322	2.36e-136	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HBBFKNIG_03323	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HBBFKNIG_03324	1.78e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HBBFKNIG_03325	8.1e-236	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBBFKNIG_03326	2.2e-171	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HBBFKNIG_03327	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HBBFKNIG_03328	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HBBFKNIG_03329	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HBBFKNIG_03330	9.73e-180	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HBBFKNIG_03331	1.65e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HBBFKNIG_03332	3.93e-119	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HBBFKNIG_03333	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBBFKNIG_03334	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBBFKNIG_03335	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HBBFKNIG_03336	2.77e-221	yccK	-	-	C	-	-	-	Aldo keto reductase
HBBFKNIG_03337	6.29e-254	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HBBFKNIG_03338	2.2e-170	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HBBFKNIG_03339	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HBBFKNIG_03340	8.4e-211	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HBBFKNIG_03341	1.01e-254	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HBBFKNIG_03342	2.31e-73	-	-	-	S	-	-	-	RDD family
HBBFKNIG_03343	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HBBFKNIG_03344	1.19e-257	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HBBFKNIG_03345	1.54e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HBBFKNIG_03346	2.87e-308	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HBBFKNIG_03347	2.81e-258	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HBBFKNIG_03348	1.99e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HBBFKNIG_03349	5.12e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HBBFKNIG_03350	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HBBFKNIG_03351	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HBBFKNIG_03352	1.75e-170	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
HBBFKNIG_03353	1.5e-101	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HBBFKNIG_03354	2.21e-76	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HBBFKNIG_03355	9.58e-147	-	-	-	S	-	-	-	ABC-2 family transporter protein
HBBFKNIG_03356	1.52e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_03357	3.75e-215	ycbM	-	-	T	-	-	-	Histidine kinase
HBBFKNIG_03358	2.61e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_03359	3.07e-214	eamA1	-	-	EG	-	-	-	spore germination
HBBFKNIG_03360	3.57e-32	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HBBFKNIG_03361	1.49e-223	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
HBBFKNIG_03362	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HBBFKNIG_03363	2.3e-161	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HBBFKNIG_03364	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HBBFKNIG_03365	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_03366	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HBBFKNIG_03367	1.95e-220	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
HBBFKNIG_03368	1.72e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HBBFKNIG_03369	1.84e-292	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_03370	2.52e-237	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HBBFKNIG_03371	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HBBFKNIG_03373	3.55e-231	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HBBFKNIG_03374	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HBBFKNIG_03375	4.3e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HBBFKNIG_03377	4.67e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HBBFKNIG_03378	8.3e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HBBFKNIG_03379	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_03380	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBBFKNIG_03381	2.35e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HBBFKNIG_03382	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
HBBFKNIG_03383	1.41e-53	ybfN	-	-	-	-	-	-	-
HBBFKNIG_03384	1.69e-187	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HBBFKNIG_03385	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HBBFKNIG_03386	5.67e-123	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBBFKNIG_03387	1.26e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HBBFKNIG_03389	4.14e-229	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HBBFKNIG_03390	2.18e-269	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HBBFKNIG_03391	3.2e-89	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
HBBFKNIG_03392	1.15e-186	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HBBFKNIG_03393	2.12e-187	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
HBBFKNIG_03394	1.19e-204	ybfH	-	-	EG	-	-	-	EamA-like transporter family
HBBFKNIG_03396	9.18e-285	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_03397	2.87e-216	ybfA	-	-	K	-	-	-	FR47-like protein
HBBFKNIG_03398	2.07e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HBBFKNIG_03399	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HBBFKNIG_03400	3.89e-208	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HBBFKNIG_03401	0.0	ybeC	-	-	E	-	-	-	amino acid
HBBFKNIG_03402	1.11e-54	ybyB	-	-	-	-	-	-	-
HBBFKNIG_03403	3.29e-315	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HBBFKNIG_03404	2.5e-191	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
HBBFKNIG_03405	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
HBBFKNIG_03406	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HBBFKNIG_03407	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HBBFKNIG_03408	2.57e-273	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
HBBFKNIG_03409	6.07e-192	ybdN	-	-	-	-	-	-	-
HBBFKNIG_03410	1.96e-178	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HBBFKNIG_03412	2.55e-215	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
HBBFKNIG_03413	6.9e-158	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
HBBFKNIG_03414	1.9e-231	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HBBFKNIG_03415	8.07e-59	-	-	-	-	-	-	-	-
HBBFKNIG_03416	7.35e-255	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HBBFKNIG_03417	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
HBBFKNIG_03418	1.03e-79	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HBBFKNIG_03419	1.6e-63	-	-	-	-	-	-	-	-
HBBFKNIG_03421	4.68e-121	ybcF	-	-	P	-	-	-	carbonic anhydrase
HBBFKNIG_03422	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
HBBFKNIG_03423	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HBBFKNIG_03424	9.21e-126	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin ABC transporter permease
HBBFKNIG_03425	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HBBFKNIG_03426	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBBFKNIG_03427	1.44e-290	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_03428	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HBBFKNIG_03429	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HBBFKNIG_03430	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBBFKNIG_03436	6.96e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HBBFKNIG_03437	8.99e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
HBBFKNIG_03438	3.18e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HBBFKNIG_03439	5.43e-194	ybbH	-	-	K	-	-	-	transcriptional
HBBFKNIG_03440	3.44e-300	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_03441	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HBBFKNIG_03442	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HBBFKNIG_03443	3.04e-298	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_03444	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HBBFKNIG_03445	1.47e-215	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HBBFKNIG_03446	2.88e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_03447	1.43e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBBFKNIG_03448	2.91e-177	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HBBFKNIG_03449	1.35e-202	ybaS	-	-	S	-	-	-	Na -dependent transporter
HBBFKNIG_03450	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HBBFKNIG_03451	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBBFKNIG_03452	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBBFKNIG_03459	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBBFKNIG_03460	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HBBFKNIG_03461	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HBBFKNIG_03462	6.03e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
HBBFKNIG_03463	8.64e-253	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HBBFKNIG_03464	1.29e-169	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HBBFKNIG_03465	1.26e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HBBFKNIG_03466	5.05e-185	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HBBFKNIG_03467	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HBBFKNIG_03468	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HBBFKNIG_03469	1.76e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HBBFKNIG_03470	4.58e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBBFKNIG_03471	2.69e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBBFKNIG_03472	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBBFKNIG_03473	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HBBFKNIG_03474	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBBFKNIG_03475	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HBBFKNIG_03476	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HBBFKNIG_03477	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HBBFKNIG_03478	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HBBFKNIG_03479	3.29e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HBBFKNIG_03480	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HBBFKNIG_03481	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HBBFKNIG_03482	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HBBFKNIG_03483	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HBBFKNIG_03484	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HBBFKNIG_03485	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HBBFKNIG_03486	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HBBFKNIG_03487	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HBBFKNIG_03488	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HBBFKNIG_03489	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HBBFKNIG_03490	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HBBFKNIG_03491	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HBBFKNIG_03492	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HBBFKNIG_03493	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HBBFKNIG_03494	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HBBFKNIG_03495	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HBBFKNIG_03496	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HBBFKNIG_03497	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HBBFKNIG_03498	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HBBFKNIG_03499	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HBBFKNIG_03500	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HBBFKNIG_03501	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HBBFKNIG_03502	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HBBFKNIG_03503	1.9e-232	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HBBFKNIG_03504	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HBBFKNIG_03505	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HBBFKNIG_03506	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HBBFKNIG_03507	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HBBFKNIG_03508	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HBBFKNIG_03509	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBBFKNIG_03510	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBBFKNIG_03511	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HBBFKNIG_03512	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HBBFKNIG_03513	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HBBFKNIG_03514	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HBBFKNIG_03515	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HBBFKNIG_03516	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HBBFKNIG_03517	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HBBFKNIG_03518	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HBBFKNIG_03519	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HBBFKNIG_03520	3.52e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBBFKNIG_03521	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HBBFKNIG_03522	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HBBFKNIG_03523	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HBBFKNIG_03524	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBBFKNIG_03525	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HBBFKNIG_03526	4.29e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HBBFKNIG_03527	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HBBFKNIG_03528	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HBBFKNIG_03529	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HBBFKNIG_03530	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HBBFKNIG_03531	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HBBFKNIG_03532	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HBBFKNIG_03533	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HBBFKNIG_03534	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBBFKNIG_03544	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBBFKNIG_03545	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HBBFKNIG_03546	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBBFKNIG_03547	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
HBBFKNIG_03548	5.33e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HBBFKNIG_03549	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HBBFKNIG_03550	1.11e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HBBFKNIG_03551	1.87e-215	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HBBFKNIG_03552	5.98e-137	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HBBFKNIG_03553	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBBFKNIG_03554	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HBBFKNIG_03555	9.49e-196	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HBBFKNIG_03556	3.88e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HBBFKNIG_03557	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HBBFKNIG_03558	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBBFKNIG_03559	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HBBFKNIG_03560	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HBBFKNIG_03561	5.93e-237	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HBBFKNIG_03562	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HBBFKNIG_03563	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HBBFKNIG_03566	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HBBFKNIG_03567	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HBBFKNIG_03568	2.03e-135	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HBBFKNIG_03569	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HBBFKNIG_03570	1.72e-49	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HBBFKNIG_03571	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HBBFKNIG_03572	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBBFKNIG_03573	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HBBFKNIG_03574	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBBFKNIG_03575	1.06e-52	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HBBFKNIG_03576	2.38e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HBBFKNIG_03577	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HBBFKNIG_03578	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBBFKNIG_03579	2.58e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HBBFKNIG_03580	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HBBFKNIG_03581	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HBBFKNIG_03582	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HBBFKNIG_03583	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HBBFKNIG_03584	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_03585	1.84e-197	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HBBFKNIG_03586	5.04e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HBBFKNIG_03587	1.43e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HBBFKNIG_03588	2.48e-279	yabE	-	-	T	-	-	-	protein conserved in bacteria
HBBFKNIG_03589	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HBBFKNIG_03590	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBBFKNIG_03591	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HBBFKNIG_03592	5.96e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HBBFKNIG_03593	1.2e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HBBFKNIG_03594	2.81e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HBBFKNIG_03595	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HBBFKNIG_03596	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HBBFKNIG_03597	1.34e-233	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HBBFKNIG_03598	2.55e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HBBFKNIG_03599	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_03600	2.82e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HBBFKNIG_03601	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HBBFKNIG_03602	4.15e-259	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HBBFKNIG_03603	1.05e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HBBFKNIG_03604	1.82e-41	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HBBFKNIG_03607	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBBFKNIG_03608	3.07e-48	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HBBFKNIG_03609	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HBBFKNIG_03610	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HBBFKNIG_03611	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HBBFKNIG_03612	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBBFKNIG_03613	3e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HBBFKNIG_03614	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HBBFKNIG_03615	4.53e-270	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HBBFKNIG_03616	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HBBFKNIG_03617	2.15e-158	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HBBFKNIG_03619	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HBBFKNIG_03620	1.93e-137	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HBBFKNIG_03621	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HBBFKNIG_03622	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HBBFKNIG_03623	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HBBFKNIG_03624	2.05e-230	yaaC	-	-	S	-	-	-	YaaC-like Protein
HBBFKNIG_03627	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBBFKNIG_03628	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBBFKNIG_03629	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBBFKNIG_03630	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HBBFKNIG_03631	1.3e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HBBFKNIG_03632	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HBBFKNIG_03633	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HBBFKNIG_03634	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HBBFKNIG_03635	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HBBFKNIG_03636	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HBBFKNIG_03637	7.47e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HBBFKNIG_03638	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HBBFKNIG_03639	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HBBFKNIG_03640	8.33e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HBBFKNIG_03641	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HBBFKNIG_03642	1.13e-98	-	-	-	S	-	-	-	Bacterial PH domain
HBBFKNIG_03643	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HBBFKNIG_03644	1.61e-190	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HBBFKNIG_03645	4.53e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HBBFKNIG_03646	2.17e-226	yyaD	-	-	S	-	-	-	Membrane
HBBFKNIG_03647	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_03648	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBBFKNIG_03649	2.3e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HBBFKNIG_03650	2.9e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HBBFKNIG_03651	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HBBFKNIG_03652	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HBBFKNIG_03653	1.15e-184	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HBBFKNIG_03654	7.68e-226	ccpB	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03655	1.4e-87	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBBFKNIG_03656	8.62e-126	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
HBBFKNIG_03657	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
HBBFKNIG_03658	1.59e-210	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HBBFKNIG_03659	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HBBFKNIG_03660	1.09e-139	-	-	-	L	-	-	-	Bpu10I restriction endonuclease
HBBFKNIG_03661	1.43e-137	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	DNA methylase
HBBFKNIG_03662	6.02e-37	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HBBFKNIG_03663	2.42e-282	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HBBFKNIG_03664	2.05e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HBBFKNIG_03665	4.93e-69	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
HBBFKNIG_03666	1.66e-100	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBBFKNIG_03667	9.28e-229	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Arsenic resistance protein
HBBFKNIG_03668	4.68e-99	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HBBFKNIG_03669	7.95e-36	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HBBFKNIG_03671	2.03e-135	yyaP	-	-	H	-	-	-	RibD C-terminal domain
HBBFKNIG_03672	1.44e-83	-	-	-	S	-	-	-	YjbR
HBBFKNIG_03673	6.41e-118	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HBBFKNIG_03674	4.99e-124	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HBBFKNIG_03675	3.44e-89	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HBBFKNIG_03676	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
HBBFKNIG_03677	4.18e-162	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HBBFKNIG_03678	6.44e-26	-	-	-	E	-	-	-	COG0346 Lactoylglutathione lyase and related lyases
HBBFKNIG_03679	1.67e-111	-	-	-	E	-	-	-	LysE type translocator
HBBFKNIG_03680	8.1e-186	-	-	-	K	-	-	-	LysR substrate binding domain
HBBFKNIG_03681	1.66e-95	yybC	-	-	-	-	-	-	-
HBBFKNIG_03682	1.26e-100	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HBBFKNIG_03683	1.86e-210	yybE	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03684	5.24e-278	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_03685	3.28e-161	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
HBBFKNIG_03686	2.05e-86	-	-	-	S	-	-	-	SnoaL-like domain
HBBFKNIG_03687	4.13e-183	-	-	-	-	-	-	-	-
HBBFKNIG_03688	1.78e-141	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
HBBFKNIG_03689	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBBFKNIG_03691	2.73e-91	-	-	-	-	-	-	-	-
HBBFKNIG_03692	5.7e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HBBFKNIG_03693	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03694	3.38e-109	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HBBFKNIG_03696	1.23e-203	yybS	-	-	S	-	-	-	membrane
HBBFKNIG_03697	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HBBFKNIG_03698	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HBBFKNIG_03699	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HBBFKNIG_03700	3.44e-282	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HBBFKNIG_03701	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
HBBFKNIG_03703	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HBBFKNIG_03704	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HBBFKNIG_03705	3.29e-99	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBBFKNIG_03706	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HBBFKNIG_03711	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_03712	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_03713	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_03714	1.2e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_03715	6.64e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HBBFKNIG_03716	2.82e-280	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBBFKNIG_03717	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HBBFKNIG_03718	7.11e-295	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HBBFKNIG_03719	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HBBFKNIG_03720	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HBBFKNIG_03722	3.03e-239	-	-	-	S	-	-	-	aspartate phosphatase
HBBFKNIG_03723	1.06e-110	yycN	-	-	K	-	-	-	Acetyltransferase
HBBFKNIG_03724	1.13e-167	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HBBFKNIG_03725	1.2e-263	yycP	-	-	-	-	-	-	-
HBBFKNIG_03726	6.44e-41	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HBBFKNIG_03728	8.26e-294	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HBBFKNIG_03729	2.15e-85	-	-	-	-	-	-	-	-
HBBFKNIG_03731	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HBBFKNIG_03732	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HBBFKNIG_03733	2.57e-169	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HBBFKNIG_03734	2.11e-184	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HBBFKNIG_03735	0.0	XK27_03440	3.1.21.5	-	V	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HBBFKNIG_03736	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HBBFKNIG_03737	8.4e-143	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBBFKNIG_03738	6.41e-151	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HBBFKNIG_03739	1.44e-24	-	-	-	-	-	-	-	-
HBBFKNIG_03740	1.13e-158	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_03741	1.67e-42	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBBFKNIG_03742	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HBBFKNIG_03743	1.11e-237	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HBBFKNIG_03744	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HBBFKNIG_03745	2.68e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HBBFKNIG_03746	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HBBFKNIG_03747	2.05e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HBBFKNIG_03748	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HBBFKNIG_03749	2.56e-163	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
HBBFKNIG_03750	1.92e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HBBFKNIG_03751	2.97e-244	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HBBFKNIG_03752	1.27e-152	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HBBFKNIG_03753	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HBBFKNIG_03754	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBBFKNIG_03755	8.67e-255	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBBFKNIG_03756	1.12e-129	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HBBFKNIG_03757	1.22e-249	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
HBBFKNIG_03758	9.22e-287	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HBBFKNIG_03759	4.7e-98	yxaI	-	-	S	-	-	-	membrane protein domain
HBBFKNIG_03760	1.18e-84	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HBBFKNIG_03761	5.06e-114	yxaL	-	-	S	-	-	-	PQQ-like domain
HBBFKNIG_03762	1.15e-41	yxaI	-	-	S	-	-	-	membrane protein domain
HBBFKNIG_03763	1.89e-310	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HBBFKNIG_03764	2.43e-264	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HBBFKNIG_03765	4.15e-193	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HBBFKNIG_03767	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HBBFKNIG_03768	4.16e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBBFKNIG_03769	2.13e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
HBBFKNIG_03771	3.52e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HBBFKNIG_03772	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HBBFKNIG_03773	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HBBFKNIG_03774	1.41e-199	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HBBFKNIG_03775	1.23e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HBBFKNIG_03776	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HBBFKNIG_03777	2.89e-221	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HBBFKNIG_03778	4.89e-297	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HBBFKNIG_03779	1.55e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HBBFKNIG_03780	5.35e-213	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HBBFKNIG_03781	3.26e-193	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HBBFKNIG_03782	2.83e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HBBFKNIG_03783	1.14e-159	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBBFKNIG_03784	2.7e-231	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBBFKNIG_03785	5.21e-179	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_03786	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HBBFKNIG_03787	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HBBFKNIG_03788	8.63e-226	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBBFKNIG_03789	6.79e-91	-	-	-	-	-	-	-	-
HBBFKNIG_03790	7.57e-28	yxeD	-	-	-	-	-	-	-
HBBFKNIG_03791	5.68e-39	yxeE	-	-	-	-	-	-	-
HBBFKNIG_03794	3.84e-192	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HBBFKNIG_03795	3.05e-234	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HBBFKNIG_03796	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBBFKNIG_03797	2.99e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBBFKNIG_03798	1.01e-184	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HBBFKNIG_03799	6.05e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HBBFKNIG_03800	4.8e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_03801	8.27e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HBBFKNIG_03802	3.55e-315	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HBBFKNIG_03803	4.09e-251	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
HBBFKNIG_03804	1.51e-196	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
HBBFKNIG_03805	1e-220	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HBBFKNIG_03806	3.38e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HBBFKNIG_03807	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBBFKNIG_03808	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HBBFKNIG_03809	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HBBFKNIG_03810	1.14e-229	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HBBFKNIG_03811	4.32e-297	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HBBFKNIG_03812	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HBBFKNIG_03813	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HBBFKNIG_03814	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HBBFKNIG_03815	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HBBFKNIG_03816	3.7e-77	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HBBFKNIG_03818	0.0	-	-	-	L	-	-	-	HKD family nuclease
HBBFKNIG_03819	5.38e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
HBBFKNIG_03820	1.33e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
HBBFKNIG_03821	8.38e-276	-	-	-	S	-	-	-	nuclease activity
HBBFKNIG_03822	2.48e-59	-	-	-	-	-	-	-	-
HBBFKNIG_03823	8.62e-32	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2247)
HBBFKNIG_03824	3.83e-55	-	-	-	-	-	-	-	-
HBBFKNIG_03825	6.87e-36	-	-	-	-	-	-	-	-
HBBFKNIG_03826	3.36e-74	-	-	-	-	-	-	-	-
HBBFKNIG_03827	7.98e-54	-	-	-	-	-	-	-	-
HBBFKNIG_03828	2.79e-27	-	-	-	-	-	-	-	-
HBBFKNIG_03829	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_03830	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HBBFKNIG_03831	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HBBFKNIG_03832	3.43e-209	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HBBFKNIG_03833	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HBBFKNIG_03836	1.95e-271	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HBBFKNIG_03837	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HBBFKNIG_03838	2.29e-293	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HBBFKNIG_03839	8.44e-140	-	-	-	-	-	-	-	-
HBBFKNIG_03840	3.27e-192	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HBBFKNIG_03841	3.06e-184	bglS	-	-	M	-	-	-	licheninase activity
HBBFKNIG_03842	1.16e-283	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HBBFKNIG_03843	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HBBFKNIG_03844	1.88e-62	yxiS	-	-	-	-	-	-	-
HBBFKNIG_03845	2.96e-133	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HBBFKNIG_03846	2.98e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBBFKNIG_03847	1.4e-200	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HBBFKNIG_03848	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HBBFKNIG_03849	1.89e-167	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBBFKNIG_03850	1.19e-150	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HBBFKNIG_03851	2.66e-172	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HBBFKNIG_03852	3.13e-275	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HBBFKNIG_03853	1.23e-276	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HBBFKNIG_03854	8.27e-111	yxjI	-	-	S	-	-	-	LURP-one-related
HBBFKNIG_03857	7.76e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HBBFKNIG_03858	1.56e-147	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
HBBFKNIG_03859	6.11e-239	-	-	-	T	-	-	-	Signal transduction histidine kinase
HBBFKNIG_03860	5.63e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
HBBFKNIG_03861	2.73e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HBBFKNIG_03862	1.16e-122	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HBBFKNIG_03863	7.06e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBBFKNIG_03864	1.83e-180	-	-	-	-	-	-	-	-
HBBFKNIG_03865	2.67e-187	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBBFKNIG_03866	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HBBFKNIG_03867	9.16e-209	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HBBFKNIG_03868	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBBFKNIG_03869	1.3e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HBBFKNIG_03871	0.0	-	-	-	O	-	-	-	Peptidase family M48
HBBFKNIG_03872	5.64e-310	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HBBFKNIG_03873	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HBBFKNIG_03874	1.77e-238	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HBBFKNIG_03875	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HBBFKNIG_03876	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HBBFKNIG_03877	1.15e-196	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBBFKNIG_03878	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HBBFKNIG_03879	2.14e-123	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBBFKNIG_03880	2.73e-53	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
HBBFKNIG_03881	5.89e-42	-	-	-	-	-	-	-	-
HBBFKNIG_03882	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HBBFKNIG_03883	1.11e-208	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBBFKNIG_03884	1.61e-178	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HBBFKNIG_03885	2.77e-271	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
HBBFKNIG_03886	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HBBFKNIG_03887	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HBBFKNIG_03888	8.94e-28	yxzF	-	-	-	-	-	-	-
HBBFKNIG_03889	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HBBFKNIG_03890	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HBBFKNIG_03891	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBBFKNIG_03892	8.33e-68	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_03893	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HBBFKNIG_03894	4.36e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HBBFKNIG_03895	2.39e-177	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBBFKNIG_03896	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HBBFKNIG_03897	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBBFKNIG_03898	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HBBFKNIG_03899	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBBFKNIG_03900	3.6e-22	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HBBFKNIG_03901	5.7e-210	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HBBFKNIG_03902	5.94e-148	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HBBFKNIG_03903	1.83e-313	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HBBFKNIG_03904	3.53e-294	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBBFKNIG_03905	5.08e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03906	1.04e-159	ywaF	-	-	S	-	-	-	Integral membrane protein
HBBFKNIG_03907	4.74e-210	gspA	-	-	M	-	-	-	General stress
HBBFKNIG_03908	9.07e-196	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HBBFKNIG_03909	4.15e-312	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_03910	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HBBFKNIG_03911	1.06e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBBFKNIG_03912	3.13e-71	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HBBFKNIG_03913	9.94e-59	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HBBFKNIG_03914	1.15e-86	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HBBFKNIG_03915	1.4e-280	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HBBFKNIG_03916	6.33e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HBBFKNIG_03917	1.44e-275	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
HBBFKNIG_03918	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HBBFKNIG_03919	1.28e-75	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HBBFKNIG_03920	6.36e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03921	5.39e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HBBFKNIG_03922	6.32e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HBBFKNIG_03923	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HBBFKNIG_03924	9.83e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
HBBFKNIG_03925	8.87e-308	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HBBFKNIG_03926	3.25e-144	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBBFKNIG_03927	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBBFKNIG_03928	2.13e-64	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
HBBFKNIG_03930	1.19e-158	ywcC	-	-	K	-	-	-	transcriptional regulator
HBBFKNIG_03931	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
HBBFKNIG_03932	1.08e-288	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HBBFKNIG_03933	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HBBFKNIG_03934	5.11e-49	ydaS	-	-	S	-	-	-	membrane
HBBFKNIG_03935	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HBBFKNIG_03936	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBBFKNIG_03937	9.9e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HBBFKNIG_03938	1.58e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HBBFKNIG_03939	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HBBFKNIG_03940	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HBBFKNIG_03941	3.15e-176	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HBBFKNIG_03942	3.3e-236	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBBFKNIG_03943	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HBBFKNIG_03945	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HBBFKNIG_03946	3.95e-51	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
HBBFKNIG_03947	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBBFKNIG_03948	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HBBFKNIG_03949	6.19e-39	ywdA	-	-	-	-	-	-	-
HBBFKNIG_03950	2.21e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HBBFKNIG_03951	1.1e-190	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HBBFKNIG_03952	2.71e-165	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HBBFKNIG_03953	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HBBFKNIG_03954	4.4e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HBBFKNIG_03955	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
HBBFKNIG_03956	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
HBBFKNIG_03957	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HBBFKNIG_03958	2.71e-185	spsA	-	-	M	-	-	-	Spore Coat
HBBFKNIG_03959	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HBBFKNIG_03960	1.85e-284	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HBBFKNIG_03961	5.75e-208	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HBBFKNIG_03962	1.95e-271	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HBBFKNIG_03963	7.39e-166	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HBBFKNIG_03964	1.06e-235	spsG	-	-	M	-	-	-	Spore Coat
HBBFKNIG_03965	7.45e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HBBFKNIG_03966	2.5e-231	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HBBFKNIG_03967	6.7e-204	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HBBFKNIG_03968	3.07e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HBBFKNIG_03969	3.7e-101	-	-	-	-	-	-	-	-
HBBFKNIG_03970	3.78e-308	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HBBFKNIG_03971	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HBBFKNIG_03972	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HBBFKNIG_03973	2.65e-316	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HBBFKNIG_03974	6.3e-274	ywfA	-	-	EGP	-	-	-	-transporter
HBBFKNIG_03975	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HBBFKNIG_03976	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HBBFKNIG_03977	9.01e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBBFKNIG_03978	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HBBFKNIG_03979	2.63e-266	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HBBFKNIG_03980	1.74e-294	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HBBFKNIG_03981	3.37e-176	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HBBFKNIG_03982	8.08e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HBBFKNIG_03983	3.37e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HBBFKNIG_03984	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HBBFKNIG_03985	2.51e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HBBFKNIG_03986	8.71e-202	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
HBBFKNIG_03987	5.39e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HBBFKNIG_03988	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HBBFKNIG_03989	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HBBFKNIG_03990	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
HBBFKNIG_03991	6.36e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03992	1.69e-297	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HBBFKNIG_03994	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HBBFKNIG_03995	1.45e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
HBBFKNIG_03996	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HBBFKNIG_03997	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
HBBFKNIG_03998	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
HBBFKNIG_03999	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HBBFKNIG_04000	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HBBFKNIG_04001	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HBBFKNIG_04003	4.26e-76	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HBBFKNIG_04006	1.52e-14	-	-	-	S	-	-	-	ABC-2 family transporter protein
HBBFKNIG_04009	2.88e-100	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HBBFKNIG_04010	6e-278	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
HBBFKNIG_04011	2.54e-303	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
HBBFKNIG_04013	1.28e-312	-	-	-	L	-	-	-	Peptidase, M16
HBBFKNIG_04014	3.44e-276	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
HBBFKNIG_04015	8.05e-296	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
HBBFKNIG_04016	6.11e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HBBFKNIG_04018	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
HBBFKNIG_04019	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
HBBFKNIG_04020	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HBBFKNIG_04021	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HBBFKNIG_04022	5.61e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HBBFKNIG_04023	2.3e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
HBBFKNIG_04024	5.27e-179	ywiC	-	-	S	-	-	-	YwiC-like protein
HBBFKNIG_04025	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
HBBFKNIG_04026	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBBFKNIG_04027	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HBBFKNIG_04028	5.59e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
HBBFKNIG_04029	3.42e-158	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
HBBFKNIG_04030	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBBFKNIG_04031	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HBBFKNIG_04032	4.52e-123	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HBBFKNIG_04033	1.32e-57	ywjC	-	-	-	-	-	-	-
HBBFKNIG_04034	8.09e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HBBFKNIG_04035	5.54e-286	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HBBFKNIG_04036	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HBBFKNIG_04037	1.21e-268	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
HBBFKNIG_04038	4.85e-81	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HBBFKNIG_04039	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HBBFKNIG_04040	1.29e-117	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HBBFKNIG_04041	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HBBFKNIG_04042	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HBBFKNIG_04043	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBBFKNIG_04044	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine