ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MFFKFOBF_00001 3.04e-150 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MFFKFOBF_00002 2.18e-240 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MFFKFOBF_00003 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MFFKFOBF_00004 1.03e-150 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00005 1.98e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MFFKFOBF_00006 7.79e-168 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MFFKFOBF_00007 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MFFKFOBF_00008 1.88e-116 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFFKFOBF_00009 2.34e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MFFKFOBF_00010 4.16e-158 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MFFKFOBF_00011 1.03e-84 - - - - - - - -
MFFKFOBF_00012 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00014 5.94e-162 pnb - - C - - - nitroreductase
MFFKFOBF_00015 2.77e-08 - - - - - - - -
MFFKFOBF_00016 3.47e-282 - - - I - - - Protein of unknown function (DUF2974)
MFFKFOBF_00017 3.33e-140 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MFFKFOBF_00018 1.83e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MFFKFOBF_00019 6.42e-299 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MFFKFOBF_00020 7.85e-285 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MFFKFOBF_00021 1.28e-188 - - - - - - - -
MFFKFOBF_00022 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFFKFOBF_00023 1.01e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MFFKFOBF_00024 7.29e-45 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MFFKFOBF_00025 1.83e-231 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MFFKFOBF_00026 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MFFKFOBF_00027 2.41e-116 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MFFKFOBF_00028 1.53e-243 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MFFKFOBF_00029 1.04e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MFFKFOBF_00030 5.62e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MFFKFOBF_00031 1.31e-70 ylbG - - S - - - UPF0298 protein
MFFKFOBF_00032 2.27e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MFFKFOBF_00033 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MFFKFOBF_00034 8.33e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MFFKFOBF_00035 3.04e-48 ykzG - - S - - - Belongs to the UPF0356 family
MFFKFOBF_00036 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFFKFOBF_00037 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MFFKFOBF_00038 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MFFKFOBF_00039 8.69e-149 - - - S - - - repeat protein
MFFKFOBF_00040 7.5e-160 pgm - - G - - - Phosphoglycerate mutase family
MFFKFOBF_00041 3.28e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MFFKFOBF_00042 2.45e-75 XK27_04120 - - S - - - Putative amino acid metabolism
MFFKFOBF_00043 3.66e-274 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MFFKFOBF_00044 1.56e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MFFKFOBF_00045 3.72e-36 - - - - - - - -
MFFKFOBF_00046 3.66e-132 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MFFKFOBF_00047 3.24e-44 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MFFKFOBF_00048 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MFFKFOBF_00049 1.14e-186 ylmH - - S - - - S4 domain protein
MFFKFOBF_00050 7.21e-62 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
MFFKFOBF_00051 1.86e-98 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MFFKFOBF_00052 4.25e-306 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MFFKFOBF_00053 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MFFKFOBF_00054 3.01e-190 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MFFKFOBF_00055 2.35e-266 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MFFKFOBF_00056 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MFFKFOBF_00057 1.09e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MFFKFOBF_00058 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MFFKFOBF_00059 1.14e-71 ftsL - - D - - - Cell division protein FtsL
MFFKFOBF_00060 2.66e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MFFKFOBF_00061 4.45e-99 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MFFKFOBF_00062 1.44e-72 - - - S - - - Protein of unknown function (DUF3397)
MFFKFOBF_00064 1.97e-124 mreD - - - ko:K03571 - ko00000,ko03036 -
MFFKFOBF_00065 5.34e-176 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MFFKFOBF_00066 9.63e-225 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MFFKFOBF_00067 3.2e-149 radC - - L ko:K03630 - ko00000 DNA repair protein
MFFKFOBF_00068 2.82e-163 - - - S - - - Haloacid dehalogenase-like hydrolase
MFFKFOBF_00069 2.14e-297 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MFFKFOBF_00070 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MFFKFOBF_00071 2.38e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MFFKFOBF_00072 1.09e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MFFKFOBF_00073 4.64e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MFFKFOBF_00074 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MFFKFOBF_00075 3.59e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MFFKFOBF_00076 8.08e-105 - - - S - - - Protein of unknown function (DUF1694)
MFFKFOBF_00077 5.39e-309 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MFFKFOBF_00078 5.05e-57 - - - - - - - -
MFFKFOBF_00079 2.07e-102 uspA - - T - - - universal stress protein
MFFKFOBF_00080 1.39e-278 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MFFKFOBF_00081 6.23e-47 - - - S - - - Protein of unknown function (DUF2969)
MFFKFOBF_00082 2.1e-62 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MFFKFOBF_00083 5.61e-226 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MFFKFOBF_00084 7.57e-44 - - - S - - - Protein of unknown function (DUF1146)
MFFKFOBF_00085 7.32e-95 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MFFKFOBF_00086 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MFFKFOBF_00087 1.66e-218 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MFFKFOBF_00088 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MFFKFOBF_00089 2.9e-122 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFFKFOBF_00090 6.38e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MFFKFOBF_00091 7.13e-39 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFFKFOBF_00092 5.39e-163 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MFFKFOBF_00093 3.18e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MFFKFOBF_00094 9.18e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MFFKFOBF_00095 3.44e-200 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MFFKFOBF_00096 2.77e-249 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MFFKFOBF_00097 1.08e-145 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MFFKFOBF_00098 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
MFFKFOBF_00099 3.69e-45 - - - - - - - -
MFFKFOBF_00100 2.97e-244 ampC - - V - - - Beta-lactamase
MFFKFOBF_00103 2.7e-25 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00104 1.94e-146 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00105 2.19e-111 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00106 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MFFKFOBF_00107 5.95e-147 vanZ - - V - - - VanZ like family
MFFKFOBF_00108 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MFFKFOBF_00109 0.0 yclK - - T - - - Histidine kinase
MFFKFOBF_00110 7.74e-173 - - - K - - - Transcriptional regulatory protein, C terminal
MFFKFOBF_00113 4.9e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MFFKFOBF_00114 2.51e-235 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MFFKFOBF_00117 1.73e-97 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
MFFKFOBF_00118 2.24e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MFFKFOBF_00119 1.43e-209 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MFFKFOBF_00120 8.06e-232 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MFFKFOBF_00121 4.12e-169 yebC - - K - - - Transcriptional regulatory protein
MFFKFOBF_00122 9.45e-121 - - - S - - - VanZ like family
MFFKFOBF_00123 3.33e-209 psaA - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MFFKFOBF_00124 9.34e-203 - - - S - - - Phospholipase, patatin family
MFFKFOBF_00125 4.18e-133 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFFKFOBF_00126 0.0 - - - E - - - Amino acid permease
MFFKFOBF_00127 7.64e-88 - - - GM - - - epimerase
MFFKFOBF_00128 2.62e-109 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFFKFOBF_00129 2e-85 - - - - - - - -
MFFKFOBF_00131 0.0 - - - T - - - Diguanylate cyclase, GGDEF domain
MFFKFOBF_00132 8.21e-142 - - - T - - - Putative diguanylate phosphodiesterase
MFFKFOBF_00133 1.05e-155 - - - T - - - diguanylate cyclase activity
MFFKFOBF_00134 5.67e-82 - - - - - - - -
MFFKFOBF_00135 6.39e-30 - - - - - - - -
MFFKFOBF_00136 2.04e-79 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFFKFOBF_00137 1.1e-85 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFFKFOBF_00138 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MFFKFOBF_00139 7.85e-84 - - - S - - - Cupredoxin-like domain
MFFKFOBF_00140 1.54e-101 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MFFKFOBF_00141 8.15e-79 - - - V - - - Beta-lactamase
MFFKFOBF_00142 1.77e-79 - - - V - - - Beta-lactamase
MFFKFOBF_00143 1.5e-189 - - - S - - - hydrolase
MFFKFOBF_00144 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MFFKFOBF_00145 2.15e-212 ybbR - - S - - - YbbR-like protein
MFFKFOBF_00146 1.1e-191 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MFFKFOBF_00147 9.47e-261 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFKFOBF_00148 2.96e-174 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00149 6.56e-184 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00150 6.4e-260 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MFFKFOBF_00151 1.25e-206 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MFFKFOBF_00152 9.43e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MFFKFOBF_00153 1.13e-112 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MFFKFOBF_00154 3.29e-234 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MFFKFOBF_00155 1.77e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MFFKFOBF_00156 6.4e-203 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MFFKFOBF_00157 1.54e-135 - - - - - - - -
MFFKFOBF_00158 5.95e-65 - - - K ko:K06977 - ko00000 acetyltransferase
MFFKFOBF_00159 2.01e-34 - - - K ko:K06977 - ko00000 acetyltransferase
MFFKFOBF_00160 3.16e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MFFKFOBF_00161 2.86e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MFFKFOBF_00162 1.42e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MFFKFOBF_00163 4.59e-270 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MFFKFOBF_00165 6.3e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00166 6.84e-192 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MFFKFOBF_00167 1.89e-13 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MFFKFOBF_00168 3.33e-68 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MFFKFOBF_00169 6.38e-14 ABC-SBP - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
MFFKFOBF_00170 5.47e-47 - - - - - - - -
MFFKFOBF_00171 9.86e-296 - - - - - - - -
MFFKFOBF_00172 1.21e-130 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MFFKFOBF_00173 1.54e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MFFKFOBF_00174 1.47e-242 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MFFKFOBF_00175 1.16e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MFFKFOBF_00176 3.52e-106 dmpA 3.4.11.19 - EQ ko:K01266 - ko00000,ko01000,ko01002 Peptidase family S58
MFFKFOBF_00177 2.61e-188 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
MFFKFOBF_00178 5.4e-118 - - - S - - - Short repeat of unknown function (DUF308)
MFFKFOBF_00179 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MFFKFOBF_00180 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MFFKFOBF_00181 2.48e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MFFKFOBF_00182 1.3e-240 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MFFKFOBF_00183 9.5e-201 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MFFKFOBF_00184 2.12e-222 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MFFKFOBF_00185 2.72e-57 - - - - - - - -
MFFKFOBF_00186 2.24e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MFFKFOBF_00187 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MFFKFOBF_00188 2.28e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MFFKFOBF_00189 3.68e-154 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MFFKFOBF_00190 1.68e-312 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MFFKFOBF_00191 1.1e-152 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MFFKFOBF_00192 1.09e-272 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MFFKFOBF_00193 1.65e-284 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MFFKFOBF_00194 1.13e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MFFKFOBF_00195 1.87e-126 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFFKFOBF_00196 2.83e-159 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MFFKFOBF_00197 1.33e-169 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MFFKFOBF_00198 3.44e-301 ymfH - - S - - - Peptidase M16
MFFKFOBF_00199 3.65e-291 ymfF - - S - - - Peptidase M16 inactive domain protein
MFFKFOBF_00200 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MFFKFOBF_00201 1.81e-90 - - - S - - - Protein of unknown function (DUF1149)
MFFKFOBF_00202 2.21e-133 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MFFKFOBF_00203 5.85e-255 XK27_05220 - - S - - - AI-2E family transporter
MFFKFOBF_00204 1.11e-84 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MFFKFOBF_00205 2.89e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MFFKFOBF_00206 3.66e-188 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MFFKFOBF_00207 7.7e-31 - - - - - - - -
MFFKFOBF_00208 1.93e-218 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MFFKFOBF_00209 7.48e-192 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFFKFOBF_00210 3.84e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MFFKFOBF_00211 4.73e-140 - - - S - - - CYTH
MFFKFOBF_00212 2.59e-144 yjbH - - Q - - - Thioredoxin
MFFKFOBF_00213 5.54e-209 coiA - - S ko:K06198 - ko00000 Competence protein
MFFKFOBF_00214 1.5e-174 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MFFKFOBF_00215 3.22e-90 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MFFKFOBF_00216 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MFFKFOBF_00217 6.14e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MFFKFOBF_00219 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MFFKFOBF_00220 4.54e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MFFKFOBF_00221 5.23e-88 sufI - - Q - - - Multicopper oxidase
MFFKFOBF_00222 1.33e-197 sufI - - Q - - - Multicopper oxidase
MFFKFOBF_00223 5.93e-39 sufI - - Q - - - Multicopper oxidase
MFFKFOBF_00224 1e-35 - - - - - - - -
MFFKFOBF_00225 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MFFKFOBF_00226 1.07e-202 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
MFFKFOBF_00227 8.66e-96 - - - - - - - -
MFFKFOBF_00228 1.75e-110 - - - - - - - -
MFFKFOBF_00229 1.89e-188 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MFFKFOBF_00230 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFFKFOBF_00231 4.5e-233 ybcH - - D ko:K06889 - ko00000 Alpha beta
MFFKFOBF_00233 2.27e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MFFKFOBF_00234 1.47e-213 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MFFKFOBF_00235 6.74e-209 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MFFKFOBF_00236 8.2e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MFFKFOBF_00237 1.26e-35 gtcA1 - - S - - - Teichoic acid glycosylation protein
MFFKFOBF_00238 1.23e-273 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MFFKFOBF_00239 7.82e-34 - - - - - - - -
MFFKFOBF_00240 4.5e-292 - - - E - - - Amino acid permease
MFFKFOBF_00242 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MFFKFOBF_00243 2.15e-299 ynbB - - P - - - aluminum resistance
MFFKFOBF_00244 5.67e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MFFKFOBF_00245 4.78e-232 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MFFKFOBF_00247 2.6e-314 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFFKFOBF_00248 1.77e-281 yfmL - - L - - - DEAD DEAH box helicase
MFFKFOBF_00249 1.5e-159 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MFFKFOBF_00250 4.62e-292 - - - E ko:K03294 - ko00000 amino acid
MFFKFOBF_00251 5.18e-134 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MFFKFOBF_00252 0.0 yhdP - - S - - - Transporter associated domain
MFFKFOBF_00253 4.16e-31 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MFFKFOBF_00256 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MFFKFOBF_00257 3.82e-168 gntR - - K - - - UbiC transcription regulator-associated domain protein
MFFKFOBF_00258 2.57e-222 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MFFKFOBF_00259 6.1e-160 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MFFKFOBF_00260 1.29e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MFFKFOBF_00261 7.49e-208 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFFKFOBF_00262 1.6e-114 - - - - - - - -
MFFKFOBF_00263 1.46e-50 - - - - - - - -
MFFKFOBF_00264 2.56e-106 - - - - - - - -
MFFKFOBF_00266 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
MFFKFOBF_00267 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MFFKFOBF_00268 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MFFKFOBF_00269 1.16e-191 - - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MFFKFOBF_00270 4.57e-142 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00271 3.27e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00272 4.65e-193 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MFFKFOBF_00273 3.81e-171 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00274 1.69e-151 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
MFFKFOBF_00275 5.48e-143 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
MFFKFOBF_00277 2.02e-131 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MFFKFOBF_00278 2.34e-266 pepA - - E - - - M42 glutamyl aminopeptidase
MFFKFOBF_00279 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MFFKFOBF_00280 6.08e-180 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MFFKFOBF_00281 4.56e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MFFKFOBF_00282 2.39e-276 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
MFFKFOBF_00283 8.24e-20 - - - - - - - -
MFFKFOBF_00286 3.46e-100 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
MFFKFOBF_00287 2.04e-147 - - - L - - - DDE superfamily endonuclease
MFFKFOBF_00288 3.86e-113 - - - L - - - DDE superfamily endonuclease
MFFKFOBF_00289 2.47e-58 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MFFKFOBF_00291 6.29e-71 - - - S - - - Alpha beta hydrolase
MFFKFOBF_00292 2.16e-202 - - - L - - - Phage integrase, N-terminal SAM-like domain
MFFKFOBF_00293 1.37e-133 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MFFKFOBF_00294 3.04e-32 - - - - - - - -
MFFKFOBF_00295 2.75e-309 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MFFKFOBF_00296 5.49e-194 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MFFKFOBF_00297 5.61e-156 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MFFKFOBF_00298 7.34e-104 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MFFKFOBF_00299 5.54e-179 - - - S - - - Peptidase family M23
MFFKFOBF_00300 1.36e-123 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MFFKFOBF_00301 4.98e-93 - - - L - - - Psort location Cytoplasmic, score
MFFKFOBF_00302 3.67e-71 - - - - - - - -
MFFKFOBF_00303 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MFFKFOBF_00304 1.25e-118 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MFFKFOBF_00305 5.59e-30 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MFFKFOBF_00306 4.57e-312 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MFFKFOBF_00307 8.18e-78 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MFFKFOBF_00308 6.44e-100 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MFFKFOBF_00309 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MFFKFOBF_00310 5e-57 celA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
MFFKFOBF_00311 1.22e-26 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFFKFOBF_00312 1.06e-257 - - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFFKFOBF_00313 1.1e-135 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MFFKFOBF_00314 1.56e-103 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MFFKFOBF_00315 2.12e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MFFKFOBF_00316 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MFFKFOBF_00317 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MFFKFOBF_00318 2.21e-228 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MFFKFOBF_00319 1.23e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MFFKFOBF_00320 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MFFKFOBF_00321 4.68e-99 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MFFKFOBF_00322 2.52e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MFFKFOBF_00323 8.25e-219 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MFFKFOBF_00324 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MFFKFOBF_00325 5.91e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MFFKFOBF_00327 2.43e-207 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFFKFOBF_00329 1.06e-10 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 SecY translocase
MFFKFOBF_00330 1.04e-288 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MFFKFOBF_00331 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MFFKFOBF_00334 3.12e-221 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MFFKFOBF_00335 6.12e-312 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MFFKFOBF_00336 7.14e-117 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MFFKFOBF_00337 2.35e-210 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
MFFKFOBF_00338 9.47e-317 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MFFKFOBF_00339 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFFKFOBF_00340 1.02e-196 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MFFKFOBF_00341 6.57e-177 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFFKFOBF_00342 1.03e-208 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MFFKFOBF_00343 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
MFFKFOBF_00344 3.72e-200 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
MFFKFOBF_00345 5.65e-151 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MFFKFOBF_00346 1.02e-280 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MFFKFOBF_00347 5.15e-216 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFFKFOBF_00349 2.5e-70 yliE - - T - - - EAL domain
MFFKFOBF_00352 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
MFFKFOBF_00353 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00354 7.28e-212 - - - K - - - LysR substrate binding domain
MFFKFOBF_00355 6.72e-204 - - - - - - - -
MFFKFOBF_00356 1.52e-129 - - - I - - - PAP2 superfamily
MFFKFOBF_00357 1.06e-193 - - - S - - - Uncharacterised protein, DegV family COG1307
MFFKFOBF_00358 9.3e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MFFKFOBF_00359 9.52e-72 - - - S - - - Protein of unknown function (DUF2752)
MFFKFOBF_00360 1.07e-232 - - - S - - - Bacterial protein of unknown function (DUF898)
MFFKFOBF_00361 5.93e-135 - - - S - - - Protein of unknown function (DUF4230)
MFFKFOBF_00362 4.91e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00363 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00364 2.08e-203 lysR5 - - K - - - LysR substrate binding domain
MFFKFOBF_00365 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MFFKFOBF_00366 1.42e-144 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MFFKFOBF_00367 8.77e-245 - - - S - - - AI-2E family transporter
MFFKFOBF_00368 1.39e-257 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MFFKFOBF_00369 1.23e-196 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MFFKFOBF_00370 9.1e-65 - - - K - - - DNA-binding transcription factor activity
MFFKFOBF_00371 8.09e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MFFKFOBF_00372 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MFFKFOBF_00373 2.03e-155 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MFFKFOBF_00374 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MFFKFOBF_00375 5.57e-237 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MFFKFOBF_00376 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MFFKFOBF_00377 1.72e-108 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MFFKFOBF_00378 2.14e-237 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MFFKFOBF_00379 1.9e-227 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MFFKFOBF_00380 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MFFKFOBF_00381 2.49e-114 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MFFKFOBF_00382 9.31e-44 - - - S - - - Uncharacterised protein family (UPF0236)
MFFKFOBF_00383 5.16e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MFFKFOBF_00384 2.93e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MFFKFOBF_00385 2.12e-70 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
MFFKFOBF_00386 1.31e-213 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MFFKFOBF_00387 2.57e-78 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MFFKFOBF_00388 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MFFKFOBF_00389 1.45e-56 ylxQ - - J - - - ribosomal protein
MFFKFOBF_00390 1.03e-57 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MFFKFOBF_00391 5.54e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MFFKFOBF_00392 5.02e-110 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MFFKFOBF_00393 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFFKFOBF_00394 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MFFKFOBF_00395 5.84e-292 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MFFKFOBF_00396 1.97e-187 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MFFKFOBF_00397 3.99e-176 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MFFKFOBF_00398 2.26e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MFFKFOBF_00399 5.02e-169 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MFFKFOBF_00400 3.29e-236 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MFFKFOBF_00401 1.49e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MFFKFOBF_00402 1.41e-243 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MFFKFOBF_00403 2.26e-149 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MFFKFOBF_00404 1.69e-231 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MFFKFOBF_00405 0.0 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MFFKFOBF_00406 9.26e-270 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MFFKFOBF_00407 1.05e-93 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MFFKFOBF_00408 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFKFOBF_00409 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFKFOBF_00410 1.55e-42 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MFFKFOBF_00411 8.7e-44 ynzC - - S - - - UPF0291 protein
MFFKFOBF_00412 2.53e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MFFKFOBF_00413 4.13e-193 - - - U ko:K05340 - ko00000,ko02000 ribose uptake protein RbsU
MFFKFOBF_00414 1.44e-198 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MFFKFOBF_00415 1.98e-123 - - - - - - - -
MFFKFOBF_00416 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
MFFKFOBF_00417 4.82e-315 - - - P - - - P-loop Domain of unknown function (DUF2791)
MFFKFOBF_00418 0.0 - - - S - - - TerB-C domain
MFFKFOBF_00419 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MFFKFOBF_00420 4.71e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MFFKFOBF_00421 8.85e-101 snf - - KL - - - domain protein
MFFKFOBF_00422 8.5e-155 snf - - KL - - - domain protein
MFFKFOBF_00423 2.91e-112 snf - - KL - - - domain protein
MFFKFOBF_00426 9.8e-178 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MFFKFOBF_00427 7.02e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MFFKFOBF_00428 3.93e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MFFKFOBF_00429 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MFFKFOBF_00430 2.27e-71 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MFFKFOBF_00431 6.22e-93 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MFFKFOBF_00432 6.88e-112 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MFFKFOBF_00433 5.31e-22 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MFFKFOBF_00434 1.71e-219 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MFFKFOBF_00435 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MFFKFOBF_00436 7.15e-164 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MFFKFOBF_00437 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MFFKFOBF_00438 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MFFKFOBF_00439 4.18e-208 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFFKFOBF_00440 2.21e-227 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00441 3.53e-228 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFKFOBF_00442 3.75e-242 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFKFOBF_00443 1.31e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFFKFOBF_00444 9.78e-232 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MFFKFOBF_00445 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MFFKFOBF_00446 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MFFKFOBF_00447 1.67e-74 yloU - - S - - - Asp23 family, cell envelope-related function
MFFKFOBF_00448 3.26e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MFFKFOBF_00449 0.0 - - - V - - - ABC transporter transmembrane region
MFFKFOBF_00453 1.76e-162 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MFFKFOBF_00454 2.01e-212 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MFFKFOBF_00455 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MFFKFOBF_00456 2.69e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MFFKFOBF_00457 2.69e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MFFKFOBF_00458 3e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MFFKFOBF_00459 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFFKFOBF_00460 1.28e-45 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MFFKFOBF_00461 2.84e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MFFKFOBF_00462 8.37e-66 - - - - - - - -
MFFKFOBF_00463 6.8e-46 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
MFFKFOBF_00464 8.36e-18 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00465 3.4e-61 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
MFFKFOBF_00466 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MFFKFOBF_00467 5.49e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MFFKFOBF_00468 1.16e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MFFKFOBF_00469 2.38e-43 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFFKFOBF_00470 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFFKFOBF_00471 4.56e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MFFKFOBF_00472 7.17e-79 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MFFKFOBF_00473 6.3e-95 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MFFKFOBF_00474 3.92e-131 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFFKFOBF_00475 3.27e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MFFKFOBF_00476 3.79e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MFFKFOBF_00477 5.61e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MFFKFOBF_00478 6.33e-87 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MFFKFOBF_00479 1.1e-119 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MFFKFOBF_00480 3.41e-73 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFKFOBF_00481 3.23e-308 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MFFKFOBF_00482 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MFFKFOBF_00483 1.17e-141 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MFFKFOBF_00484 2.39e-253 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MFFKFOBF_00485 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MFFKFOBF_00486 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFFKFOBF_00487 1.98e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFFKFOBF_00488 8.7e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFFKFOBF_00489 5.04e-173 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MFFKFOBF_00490 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MFFKFOBF_00491 5.55e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MFFKFOBF_00492 1.42e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MFFKFOBF_00493 1.66e-55 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
MFFKFOBF_00494 1.61e-187 - - - EGP - - - Major Facilitator Superfamily
MFFKFOBF_00495 1.11e-105 - - - - - - - -
MFFKFOBF_00496 2.64e-139 - - - - - - - -
MFFKFOBF_00497 0.0 - - - S - - - SH3-like domain
MFFKFOBF_00498 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MFFKFOBF_00500 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MFFKFOBF_00501 2.32e-314 - - - EGP - - - Major Facilitator
MFFKFOBF_00502 2.71e-73 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
MFFKFOBF_00503 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MFFKFOBF_00504 8.99e-104 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MFFKFOBF_00505 5.29e-120 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MFFKFOBF_00506 1.33e-16 - - - Q - - - phosphatase activity
MFFKFOBF_00507 2.51e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
MFFKFOBF_00508 1.41e-98 - - - K - - - DNA-binding transcription factor activity
MFFKFOBF_00509 1.76e-84 - - - S - - - Aminoacyl-tRNA editing domain
MFFKFOBF_00510 1.67e-222 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MFFKFOBF_00511 1.87e-195 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MFFKFOBF_00512 3.46e-216 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MFFKFOBF_00513 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MFFKFOBF_00514 7.71e-165 - - - F - - - Phosphorylase superfamily
MFFKFOBF_00516 9.97e-163 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFKFOBF_00517 1.13e-169 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00518 4.74e-177 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MFFKFOBF_00521 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFFKFOBF_00522 8.57e-188 - - - K - - - Transcriptional regulator
MFFKFOBF_00523 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MFFKFOBF_00524 0.0 - - - KLT - - - Protein kinase domain
MFFKFOBF_00525 7.29e-84 - - - S - - - HicB family
MFFKFOBF_00526 5.02e-52 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
MFFKFOBF_00527 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MFFKFOBF_00528 2.95e-263 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFFKFOBF_00529 2.76e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MFFKFOBF_00530 7.66e-291 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MFFKFOBF_00531 6.71e-85 - - - - - - - -
MFFKFOBF_00532 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MFFKFOBF_00533 1.71e-241 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFFKFOBF_00534 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MFFKFOBF_00535 2.29e-85 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFFKFOBF_00536 6.11e-96 - - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MFFKFOBF_00537 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Papain family cysteine protease
MFFKFOBF_00538 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MFFKFOBF_00539 1.33e-227 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFKFOBF_00540 2.78e-251 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFKFOBF_00541 3.19e-239 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFFKFOBF_00542 1.09e-200 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFFKFOBF_00543 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFKFOBF_00544 1.07e-121 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00545 8.04e-158 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00546 5.19e-42 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
MFFKFOBF_00547 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00548 5.77e-218 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00549 1.98e-76 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00550 9.42e-30 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00551 3.71e-154 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MFFKFOBF_00552 5.16e-311 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MFFKFOBF_00553 1.74e-131 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MFFKFOBF_00554 2.29e-297 amd - - E - - - Peptidase family M20/M25/M40
MFFKFOBF_00555 5.23e-62 steT - - E ko:K03294 - ko00000 amino acid
MFFKFOBF_00556 4.09e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MFFKFOBF_00557 3.02e-67 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MFFKFOBF_00558 2.59e-115 - - - L - - - DDE superfamily endonuclease
MFFKFOBF_00560 7.6e-307 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFFKFOBF_00562 2.53e-205 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MFFKFOBF_00563 8.35e-175 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00564 1.39e-121 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00565 1.32e-144 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
MFFKFOBF_00566 9.53e-21 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
MFFKFOBF_00567 2.7e-126 - 3.6.1.67 - F ko:K19965 ko00790,map00790 ko00000,ko00001,ko00002,ko01000 NUDIX domain
MFFKFOBF_00568 7.12e-256 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
MFFKFOBF_00569 4.67e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MFFKFOBF_00570 1.24e-259 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
MFFKFOBF_00571 2.82e-73 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MFFKFOBF_00572 1.61e-68 - - - S - - - Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
MFFKFOBF_00573 0.0 XK27_08315 - - M - - - Sulfatase
MFFKFOBF_00574 6.93e-140 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MFFKFOBF_00575 9.16e-272 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MFFKFOBF_00576 2.71e-167 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MFFKFOBF_00577 3.94e-170 - - - - - - - -
MFFKFOBF_00578 2.47e-75 - - - S - - - Oxidoreductase
MFFKFOBF_00579 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MFFKFOBF_00580 2.94e-41 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
MFFKFOBF_00581 5.83e-237 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
MFFKFOBF_00582 2.71e-262 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFFKFOBF_00583 6.35e-46 - - - S - - - Protein of unknown function (DUF2922)
MFFKFOBF_00584 1.23e-39 - - - - - - - -
MFFKFOBF_00585 2.18e-177 - - - - - - - -
MFFKFOBF_00586 2.42e-96 - - - - - - - -
MFFKFOBF_00587 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MFFKFOBF_00588 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MFFKFOBF_00589 8.87e-82 - - - O - - - Glutaredoxin-related protein
MFFKFOBF_00590 1.37e-290 yqjV - - EGP - - - Major Facilitator Superfamily
MFFKFOBF_00591 5.06e-62 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MFFKFOBF_00592 9.31e-44 yitW - - S - - - Iron-sulfur cluster assembly protein
MFFKFOBF_00593 7.21e-182 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MFFKFOBF_00594 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MFFKFOBF_00595 4.44e-314 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MFFKFOBF_00596 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MFFKFOBF_00597 0.0 - - - S - - - Calcineurin-like phosphoesterase
MFFKFOBF_00598 3e-108 - - - - - - - -
MFFKFOBF_00599 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00600 4.49e-191 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFFKFOBF_00601 1.59e-173 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFFKFOBF_00602 2.39e-179 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MFFKFOBF_00603 4.69e-210 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MFFKFOBF_00604 3.15e-108 usp5 - - T - - - universal stress protein
MFFKFOBF_00605 8.73e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MFFKFOBF_00606 1.09e-109 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MFFKFOBF_00607 2.59e-116 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
MFFKFOBF_00608 2.51e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MFFKFOBF_00609 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
MFFKFOBF_00610 2.17e-185 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00611 5.02e-128 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFFKFOBF_00612 1.46e-109 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
MFFKFOBF_00613 4.6e-218 - - - I - - - alpha/beta hydrolase fold
MFFKFOBF_00614 1.98e-166 yibF - - S - - - overlaps another CDS with the same product name
MFFKFOBF_00615 2.61e-242 yibE - - S - - - overlaps another CDS with the same product name
MFFKFOBF_00618 1.41e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MFFKFOBF_00619 2.33e-233 - - - S - - - Cysteine-rich secretory protein family
MFFKFOBF_00620 2.41e-150 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MFFKFOBF_00621 1.67e-185 - - - - - - - -
MFFKFOBF_00622 1.5e-158 - - - K - - - Bacterial regulatory proteins, tetR family
MFFKFOBF_00623 1.03e-237 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFFKFOBF_00624 1.92e-162 - - - S - - - Alpha/beta hydrolase family
MFFKFOBF_00625 2.85e-205 epsV - - S - - - glycosyl transferase family 2
MFFKFOBF_00626 8.04e-209 - - - S - - - Protein of unknown function (DUF1002)
MFFKFOBF_00627 2.48e-176 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFFKFOBF_00628 1.9e-230 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MFFKFOBF_00629 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFFKFOBF_00630 5e-106 - - - - - - - -
MFFKFOBF_00631 1.24e-169 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MFFKFOBF_00632 3.9e-88 yeaO - - S - - - Protein of unknown function, DUF488
MFFKFOBF_00633 5.98e-156 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MFFKFOBF_00634 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00635 2.81e-181 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00637 3.46e-154 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MFFKFOBF_00638 4.61e-221 - - - L - - - HNH nucleases
MFFKFOBF_00639 2.02e-23 - - - - - - - -
MFFKFOBF_00640 8.42e-261 ysdE - - P - - - Citrate transporter
MFFKFOBF_00641 1.67e-123 lemA - - S ko:K03744 - ko00000 LemA family
MFFKFOBF_00642 2.7e-202 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MFFKFOBF_00643 5.66e-194 mutR - - K - - - Helix-turn-helix XRE-family like proteins
MFFKFOBF_00644 4.84e-284 - - - S ko:K09136 - ko00000,ko03009 ATP diphosphatase activity
MFFKFOBF_00646 6.57e-176 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MFFKFOBF_00647 2.22e-155 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MFFKFOBF_00648 1.27e-219 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MFFKFOBF_00649 1.75e-194 - - - K - - - helix_turn_helix, arabinose operon control protein
MFFKFOBF_00650 2.37e-179 qacA - - EGP - - - Major Facilitator
MFFKFOBF_00651 4.51e-139 qacA - - EGP - - - Major Facilitator
MFFKFOBF_00652 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00653 7.38e-148 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MFFKFOBF_00654 1.15e-101 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
MFFKFOBF_00655 5.35e-81 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MFFKFOBF_00660 3.52e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MFFKFOBF_00661 3.7e-239 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MFFKFOBF_00662 3.71e-192 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MFFKFOBF_00663 2.67e-181 yycI - - S - - - YycH protein
MFFKFOBF_00664 2.36e-313 yycH - - S - - - YycH protein
MFFKFOBF_00665 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFKFOBF_00666 1.09e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MFFKFOBF_00668 3.19e-194 - - - I - - - Acyl-transferase
MFFKFOBF_00669 5.09e-199 arbx - - M - - - Glycosyl transferase family 8
MFFKFOBF_00670 2.72e-121 - - - M - - - Glycosyl transferase family 8
MFFKFOBF_00671 1.86e-212 arbZ - - I - - - Phosphate acyltransferases
MFFKFOBF_00672 7.52e-24 - - - - - - - -
MFFKFOBF_00673 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MFFKFOBF_00674 6.06e-222 - - - K - - - Transcriptional regulator, LysR family
MFFKFOBF_00675 5.62e-189 - - - EGP - - - Major Facilitator Superfamily
MFFKFOBF_00676 3.15e-126 - - - S - - - Membrane
MFFKFOBF_00677 2.24e-281 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
MFFKFOBF_00678 4.37e-212 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MFFKFOBF_00679 6.27e-219 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MFFKFOBF_00681 1.48e-271 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MFFKFOBF_00682 2.57e-16 cpsY - - K - - - Transcriptional regulator, LysR family
MFFKFOBF_00683 2.05e-177 cpsY - - K - - - Transcriptional regulator, LysR family
MFFKFOBF_00684 1.06e-166 - - - - - - - -
MFFKFOBF_00685 3.12e-314 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MFFKFOBF_00686 1.24e-16 - 1.3.8.1, 1.3.8.7 - I ko:K00248,ko:K00249,ko:K18244 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 ko00000,ko00001,ko00002,ko01000 Acyl-CoA dehydrogenase, C-terminal domain
MFFKFOBF_00687 1.27e-74 - - - - - - - -
MFFKFOBF_00689 4.44e-110 - - - L - - - Putative transposase DNA-binding domain
MFFKFOBF_00690 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MFFKFOBF_00691 2.74e-214 - - - S ko:K07088 - ko00000 Membrane transport protein
MFFKFOBF_00692 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MFFKFOBF_00693 3.83e-84 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MFFKFOBF_00694 6.29e-10 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MFFKFOBF_00695 9.32e-70 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional antiterminator
MFFKFOBF_00696 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MFFKFOBF_00697 3.25e-112 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
MFFKFOBF_00698 3.19e-62 - - - S ko:K08987 - ko00000 membrane
MFFKFOBF_00699 1.17e-34 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MFFKFOBF_00701 5.53e-50 - - - T - - - Gaf domain
MFFKFOBF_00702 1.09e-110 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NUDIX domain
MFFKFOBF_00703 4.88e-159 alkD - - L - - - DNA alkylation repair enzyme
MFFKFOBF_00704 2.19e-305 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MFFKFOBF_00705 1.82e-145 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MFFKFOBF_00706 1.64e-61 - - - D - - - Di-iron-containing protein involved in the repair of iron-sulfur clusters
MFFKFOBF_00707 6.01e-45 copZ - - P - - - Heavy-metal-associated domain
MFFKFOBF_00708 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MFFKFOBF_00709 5.44e-90 - - - C - - - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MFFKFOBF_00710 3.77e-81 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MFFKFOBF_00711 3.59e-154 - 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
MFFKFOBF_00712 1.31e-159 - - - L ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
MFFKFOBF_00713 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFFKFOBF_00714 2.18e-158 ybbB - - S - - - Protein of unknown function (DUF1211)
MFFKFOBF_00715 5.36e-218 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MFFKFOBF_00716 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFFKFOBF_00717 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MFFKFOBF_00718 3.99e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFFKFOBF_00719 1.98e-259 camS - - S - - - sex pheromone
MFFKFOBF_00720 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MFFKFOBF_00721 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MFFKFOBF_00722 6.12e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MFFKFOBF_00723 7.97e-131 - - - S - - - ECF transporter, substrate-specific component
MFFKFOBF_00725 2.99e-119 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MFFKFOBF_00726 2.97e-143 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MFFKFOBF_00729 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MFFKFOBF_00730 3.16e-194 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MFFKFOBF_00731 1.77e-174 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MFFKFOBF_00732 1.02e-258 - - - M - - - Glycosyl transferases group 1
MFFKFOBF_00733 3.4e-173 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MFFKFOBF_00734 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MFFKFOBF_00735 4.01e-283 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFFKFOBF_00736 8.01e-162 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
MFFKFOBF_00737 3.27e-254 - - - - - - - -
MFFKFOBF_00738 6.54e-273 - - - - - - - -
MFFKFOBF_00739 2.91e-28 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MFFKFOBF_00740 6.84e-90 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00743 3.07e-225 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MFFKFOBF_00744 4.22e-286 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MFFKFOBF_00747 1.8e-119 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MFFKFOBF_00748 1.72e-98 - - - EGP - - - Major Facilitator
MFFKFOBF_00749 3.54e-28 - - - EGP - - - Major Facilitator
MFFKFOBF_00750 1.73e-19 - - - EGP - - - Major Facilitator
MFFKFOBF_00751 2.43e-152 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MFFKFOBF_00752 6.56e-16 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00753 3.88e-237 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00754 5.07e-61 - - - - - - - -
MFFKFOBF_00755 9.68e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MFFKFOBF_00756 1.54e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MFFKFOBF_00757 8.77e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MFFKFOBF_00758 1.28e-183 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFFKFOBF_00759 2.44e-208 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFFKFOBF_00760 5.7e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFFKFOBF_00761 1.91e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MFFKFOBF_00762 7.63e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFFKFOBF_00763 6.6e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MFFKFOBF_00764 5.08e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MFFKFOBF_00765 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MFFKFOBF_00766 6.92e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MFFKFOBF_00767 5.33e-303 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MFFKFOBF_00768 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MFFKFOBF_00769 1.1e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MFFKFOBF_00770 4.52e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MFFKFOBF_00771 1.55e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MFFKFOBF_00772 2.92e-120 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MFFKFOBF_00773 9.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MFFKFOBF_00774 1.75e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MFFKFOBF_00775 5.64e-45 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MFFKFOBF_00776 1.73e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MFFKFOBF_00777 1.34e-56 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MFFKFOBF_00778 9.34e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MFFKFOBF_00779 8.89e-101 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MFFKFOBF_00780 2.31e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MFFKFOBF_00781 3.7e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MFFKFOBF_00782 1.79e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MFFKFOBF_00783 2.82e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MFFKFOBF_00784 1.72e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MFFKFOBF_00785 6.65e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MFFKFOBF_00786 3.42e-142 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MFFKFOBF_00787 1.55e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MFFKFOBF_00788 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MFFKFOBF_00789 6.89e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MFFKFOBF_00790 2.96e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MFFKFOBF_00791 3.01e-11 - - - Q - - - phosphatase activity
MFFKFOBF_00792 1.83e-09 - - - S - - - hydrolase
MFFKFOBF_00794 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFFKFOBF_00795 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFFKFOBF_00798 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MFFKFOBF_00799 9.11e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MFFKFOBF_00803 3.88e-140 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
MFFKFOBF_00804 5.04e-278 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MFFKFOBF_00805 4.18e-31 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
MFFKFOBF_00807 2.58e-31 - - - T ko:K03320 - ko00000,ko02000 GGDEF domain
MFFKFOBF_00808 5.51e-117 - - - T ko:K03320 - ko00000,ko02000 GGDEF domain
MFFKFOBF_00810 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MFFKFOBF_00811 1.09e-251 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFFKFOBF_00812 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MFFKFOBF_00813 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_00814 8.18e-210 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MFFKFOBF_00815 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFFKFOBF_00816 1.93e-316 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MFFKFOBF_00817 4.32e-80 - - - J ko:K07571 - ko00000 S1 RNA binding domain
MFFKFOBF_00818 1.99e-78 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MFFKFOBF_00819 1.48e-45 yabO - - J - - - S4 domain protein
MFFKFOBF_00820 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MFFKFOBF_00821 5.2e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MFFKFOBF_00822 9.02e-163 - - - S - - - (CBS) domain
MFFKFOBF_00823 3.26e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MFFKFOBF_00824 3.58e-93 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MFFKFOBF_00825 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MFFKFOBF_00826 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MFFKFOBF_00827 3.27e-55 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MFFKFOBF_00828 1.26e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFFKFOBF_00829 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MFFKFOBF_00830 3.45e-91 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MFFKFOBF_00831 1.73e-84 - - - S - - - Domain of unknown function (DUF1934)
MFFKFOBF_00832 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MFFKFOBF_00833 1.27e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFFKFOBF_00834 3.49e-61 - - - - - - - -
MFFKFOBF_00835 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MFFKFOBF_00836 4.31e-192 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MFFKFOBF_00837 4.13e-51 veg - - S - - - Biofilm formation stimulator VEG
MFFKFOBF_00838 1.57e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MFFKFOBF_00839 3.34e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MFFKFOBF_00840 3.17e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MFFKFOBF_00841 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MFFKFOBF_00842 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
MFFKFOBF_00843 7.13e-134 - - - S ko:K06872 - ko00000 TPM domain
MFFKFOBF_00844 2.79e-117 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
MFFKFOBF_00845 9.25e-247 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MFFKFOBF_00847 5.04e-155 - - - - - - - -
MFFKFOBF_00848 1.64e-137 - - - KLT - - - Protein kinase domain
MFFKFOBF_00849 3.82e-166 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MFFKFOBF_00850 2.74e-174 - - - V - - - ABC-2 type transporter
MFFKFOBF_00851 4.55e-148 - - - E - - - peptidase
MFFKFOBF_00853 4.4e-54 - - - S - - - Enterocin A Immunity
MFFKFOBF_00854 0.0 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MFFKFOBF_00855 2.32e-187 - - - F - - - NUDIX domain
MFFKFOBF_00856 1.9e-56 - - - L - - - Membrane
MFFKFOBF_00857 1.07e-144 - - - - - - - -
MFFKFOBF_00858 4.64e-139 pncA - - Q - - - Isochorismatase family
MFFKFOBF_00859 3e-83 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MFFKFOBF_00860 8.33e-33 - - - T - - - diguanylate cyclase
MFFKFOBF_00861 1.94e-80 - - - T - - - diguanylate cyclase
MFFKFOBF_00862 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
MFFKFOBF_00863 7.46e-50 - - - - - - - -
MFFKFOBF_00864 2.24e-167 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MFFKFOBF_00865 1.19e-306 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MFFKFOBF_00866 2.68e-90 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MFFKFOBF_00867 6.12e-72 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MFFKFOBF_00868 8.61e-229 - - - KLT - - - serine threonine protein kinase
MFFKFOBF_00869 1.52e-82 - - - KLT - - - serine threonine protein kinase
MFFKFOBF_00870 8.75e-155 - - - KLT - - - serine threonine protein kinase
MFFKFOBF_00871 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MFFKFOBF_00872 1.36e-187 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MFFKFOBF_00873 7.6e-118 ymdB - - S - - - Macro domain protein
MFFKFOBF_00874 8.57e-197 - - - - - - - -
MFFKFOBF_00877 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MFFKFOBF_00878 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MFFKFOBF_00880 0.0 - - - M ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
MFFKFOBF_00881 4.77e-220 citI - - K - - - Putative sugar-binding domain
MFFKFOBF_00882 1.49e-45 lysM - - M - - - LysM domain
MFFKFOBF_00883 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MFFKFOBF_00884 1.04e-38 drgA - - C - - - coenzyme F420-1:gamma-L-glutamate ligase activity
MFFKFOBF_00885 1.18e-19 ydgI - - C - - - Nitroreductase family
MFFKFOBF_00886 1.04e-289 - - - S - - - Putative peptidoglycan binding domain
MFFKFOBF_00887 6.95e-152 - - - - - - - -
MFFKFOBF_00888 4.86e-178 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MFFKFOBF_00889 5.02e-22 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MFFKFOBF_00890 3.45e-204 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MFFKFOBF_00891 4.04e-109 - - - K - - - transcriptional regulator (TetR family)
MFFKFOBF_00892 5.88e-235 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MFFKFOBF_00893 1.68e-154 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00894 2.04e-168 - - - - - - - -
MFFKFOBF_00896 3.24e-138 - - - - - - - -
MFFKFOBF_00897 3.98e-151 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MFFKFOBF_00899 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MFFKFOBF_00900 4.76e-127 - - - K - - - WHG domain
MFFKFOBF_00901 1.76e-127 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MFFKFOBF_00902 6.08e-125 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MFFKFOBF_00903 5.87e-182 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MFFKFOBF_00904 6.68e-238 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MFFKFOBF_00905 1.5e-112 cvpA - - S - - - Colicin V production protein
MFFKFOBF_00906 3.68e-170 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MFFKFOBF_00907 2.19e-184 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MFFKFOBF_00908 2.37e-176 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MFFKFOBF_00909 4.14e-200 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MFFKFOBF_00910 1.1e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MFFKFOBF_00911 6.88e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MFFKFOBF_00912 7.67e-176 - - - S - - - Protein of unknown function (DUF1129)
MFFKFOBF_00913 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00914 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MFFKFOBF_00915 1.01e-157 vanR - - K - - - response regulator
MFFKFOBF_00916 4.19e-283 - - - T - - - His Kinase A (phosphoacceptor) domain
MFFKFOBF_00917 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MFFKFOBF_00918 3.86e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MFFKFOBF_00919 8.52e-39 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MFFKFOBF_00920 1.07e-93 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MFFKFOBF_00921 8.15e-211 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MFFKFOBF_00922 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MFFKFOBF_00923 1.01e-185 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MFFKFOBF_00924 6.92e-155 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MFFKFOBF_00925 2.09e-173 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MFFKFOBF_00926 3.47e-114 - - - KT - - - response to antibiotic
MFFKFOBF_00927 4.07e-123 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MFFKFOBF_00928 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MFFKFOBF_00929 6.18e-262 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MFFKFOBF_00931 0.0 - - - S - - - ABC transporter, ATP-binding protein
MFFKFOBF_00932 7.94e-174 - - - S - - - Putative threonine/serine exporter
MFFKFOBF_00933 8.56e-109 - - - S - - - Threonine/Serine exporter, ThrE
MFFKFOBF_00934 1.96e-102 - - - - - - - -
MFFKFOBF_00935 6.66e-144 - - - - - - - -
MFFKFOBF_00936 0.0 - - - S - - - O-antigen ligase like membrane protein
MFFKFOBF_00937 2.89e-64 - - - - - - - -
MFFKFOBF_00938 6.35e-126 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
MFFKFOBF_00939 6.05e-108 lytE - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family
MFFKFOBF_00940 1.62e-255 idhA 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFFKFOBF_00941 5.87e-104 lytE - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MFFKFOBF_00942 7.39e-160 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MFFKFOBF_00943 8.34e-91 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MFFKFOBF_00944 3.3e-39 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MFFKFOBF_00945 1.54e-118 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MFFKFOBF_00946 5.62e-159 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MFFKFOBF_00947 3.69e-296 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MFFKFOBF_00948 1.33e-231 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MFFKFOBF_00949 3.73e-145 epsB - - M - - - biosynthesis protein
MFFKFOBF_00950 9.29e-153 ywqD - - D - - - Capsular exopolysaccharide family
MFFKFOBF_00951 6.64e-187 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MFFKFOBF_00952 3.43e-156 epsE2 - - M - - - Bacterial sugar transferase
MFFKFOBF_00953 4.69e-113 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
MFFKFOBF_00954 2.73e-107 - - - S - - - Glycosyltransferase family 28 C-terminal domain
MFFKFOBF_00955 1.01e-239 - - - S - - - Polysaccharide pyruvyl transferase
MFFKFOBF_00956 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MFFKFOBF_00957 9.34e-79 - 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 reductase
MFFKFOBF_00958 8.28e-237 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MFFKFOBF_00959 1.03e-202 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MFFKFOBF_00960 4.61e-167 - - - M - - - Glycosyltransferase like family 2
MFFKFOBF_00962 6.51e-92 - - - M - - - Glycosyltransferase like family 2
MFFKFOBF_00963 2.95e-222 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MFFKFOBF_00964 7.73e-07 - - - - - - - -
MFFKFOBF_00966 1.73e-234 - - - S ko:K06915 - ko00000 AAA-like domain
MFFKFOBF_00967 5.66e-82 - - - - - - - -
MFFKFOBF_00968 4.86e-35 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MFFKFOBF_00969 1.25e-49 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MFFKFOBF_00970 3.11e-266 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFFKFOBF_00971 4.18e-105 - - - L - - - MgsA AAA+ ATPase C terminal
MFFKFOBF_00972 8.63e-122 - - - K - - - Helix-turn-helix domain, rpiR family
MFFKFOBF_00973 7.99e-71 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
MFFKFOBF_00974 5.55e-155 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MFFKFOBF_00975 1.38e-14 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MFFKFOBF_00976 2.5e-09 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MFFKFOBF_00977 7.54e-48 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
MFFKFOBF_00978 4.84e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MFFKFOBF_00979 1.56e-123 - - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_00980 3.56e-110 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MFFKFOBF_00981 3.37e-64 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MFFKFOBF_00983 5.62e-37 - - - - - - - -
MFFKFOBF_00984 3.51e-44 - - - L - - - Transposase
MFFKFOBF_00985 4.17e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MFFKFOBF_00986 1.34e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MFFKFOBF_00987 1.64e-136 - - - S - - - Protein of unknown function (DUF1461)
MFFKFOBF_00988 5.46e-185 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MFFKFOBF_00989 5.27e-112 yutD - - S - - - Protein of unknown function (DUF1027)
MFFKFOBF_00990 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MFFKFOBF_00991 2.89e-77 - - - - - - - -
MFFKFOBF_00992 6.12e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MFFKFOBF_00993 2.77e-273 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MFFKFOBF_00995 5.67e-34 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MFFKFOBF_00996 9.8e-59 - - - - - - - -
MFFKFOBF_00997 1.1e-27 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MFFKFOBF_00998 8.05e-196 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MFFKFOBF_00999 1.03e-146 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MFFKFOBF_01000 1.01e-87 yslB - - S - - - Protein of unknown function (DUF2507)
MFFKFOBF_01001 3.78e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MFFKFOBF_01002 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MFFKFOBF_01003 1.92e-67 yrzB - - S - - - Belongs to the UPF0473 family
MFFKFOBF_01004 6.34e-94 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MFFKFOBF_01005 3.09e-56 yrzL - - S - - - Belongs to the UPF0297 family
MFFKFOBF_01006 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MFFKFOBF_01007 1.74e-294 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MFFKFOBF_01008 1.89e-228 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MFFKFOBF_01009 4.03e-263 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFFKFOBF_01010 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MFFKFOBF_01011 1.21e-70 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MFFKFOBF_01012 1.02e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MFFKFOBF_01013 4.05e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MFFKFOBF_01014 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MFFKFOBF_01015 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MFFKFOBF_01016 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MFFKFOBF_01017 3.69e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MFFKFOBF_01018 2.3e-158 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MFFKFOBF_01019 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MFFKFOBF_01020 1.66e-247 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MFFKFOBF_01021 3.7e-123 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MFFKFOBF_01022 5.82e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MFFKFOBF_01023 5.44e-116 - - - S - - - ECF transporter, substrate-specific component
MFFKFOBF_01024 2.15e-183 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MFFKFOBF_01025 2.62e-203 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MFFKFOBF_01026 2.21e-72 yabA - - L - - - Involved in initiation control of chromosome replication
MFFKFOBF_01027 5.96e-206 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MFFKFOBF_01028 6.39e-71 yaaQ - - S - - - Cyclic-di-AMP receptor
MFFKFOBF_01029 2.32e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MFFKFOBF_01030 2.21e-46 - - - S - - - Protein of unknown function (DUF2508)
MFFKFOBF_01031 3.6e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MFFKFOBF_01032 1.9e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MFFKFOBF_01033 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFFKFOBF_01034 7.85e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MFFKFOBF_01035 4.22e-143 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MFFKFOBF_01036 2.31e-117 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MFFKFOBF_01037 1.31e-199 - - - - - - - -
MFFKFOBF_01038 3.19e-59 - - - - - - - -
MFFKFOBF_01039 3.43e-19 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
MFFKFOBF_01041 7.54e-264 pbpX1 - - V - - - Beta-lactamase
MFFKFOBF_01042 6.81e-273 pbpX - - V - - - Beta-lactamase
MFFKFOBF_01043 1.49e-54 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MFFKFOBF_01044 3.95e-16 - 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose/Galactose Isomerase
MFFKFOBF_01045 1.84e-27 - 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose/Galactose Isomerase
MFFKFOBF_01046 1.22e-15 rpiB2 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose/Galactose Isomerase
MFFKFOBF_01048 1.81e-109 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MFFKFOBF_01049 9.06e-187 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_01050 3.21e-110 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_01051 1.42e-71 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MFFKFOBF_01052 1.35e-108 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MFFKFOBF_01053 9.62e-317 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MFFKFOBF_01054 5.15e-91 - - - - - - - -
MFFKFOBF_01055 1.62e-294 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MFFKFOBF_01056 2.09e-244 - - - S - - - Glycosyl transferase family 2
MFFKFOBF_01057 4.45e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MFFKFOBF_01058 3.27e-91 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MFFKFOBF_01059 5.63e-131 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MFFKFOBF_01060 3.07e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MFFKFOBF_01061 7.32e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MFFKFOBF_01062 9.75e-72 dxs 2.2.1.7 - HI ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 1-deoxy-D-xylulose-5-phosphate synthase
MFFKFOBF_01063 7.14e-128 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MFFKFOBF_01064 2.17e-115 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MFFKFOBF_01065 2.02e-153 - - - S - - - Alpha/beta hydrolase family
MFFKFOBF_01066 3.19e-45 - - - - - - - -
MFFKFOBF_01067 5.81e-131 - - - K ko:K03091 - ko00000,ko03021 sigma factor activity
MFFKFOBF_01068 5.44e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFFKFOBF_01069 6.26e-101 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MFFKFOBF_01070 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MFFKFOBF_01071 7.09e-136 - - - F - - - NUDIX domain
MFFKFOBF_01072 5.29e-205 - - - K - - - LysR substrate binding domain
MFFKFOBF_01073 2.3e-231 - - - S - - - Conserved hypothetical protein 698
MFFKFOBF_01074 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MFFKFOBF_01076 1.88e-155 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MFFKFOBF_01077 1.26e-79 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MFFKFOBF_01078 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_01079 3.57e-120 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MFFKFOBF_01080 7.14e-298 - - - F - - - Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MFFKFOBF_01081 6.69e-228 - 6.3.4.18, 6.3.5.5 - F ko:K01589,ko:K01955,ko:K16181 ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 5-(carboxyamino)imidazole ribonucleotide synthase activity
MFFKFOBF_01082 1.32e-31 - 6.3.4.18, 6.3.5.5 - F ko:K01589,ko:K01955,ko:K16181 ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 5-(carboxyamino)imidazole ribonucleotide synthase activity
MFFKFOBF_01083 9.52e-205 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MFFKFOBF_01084 6.14e-259 - - - - - - - -
MFFKFOBF_01085 5.81e-243 - - - EGP - - - Transmembrane secretion effector
MFFKFOBF_01086 4.78e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MFFKFOBF_01087 5.52e-92 - - - T - - - diguanylate cyclase
MFFKFOBF_01088 1.12e-19 - - - T - - - diguanylate cyclase
MFFKFOBF_01089 3.58e-142 - - - T - - - EAL domain
MFFKFOBF_01090 7.24e-15 - - - T - - - diguanylate cyclase
MFFKFOBF_01091 4.21e-111 - - - S - - - ECF-type riboflavin transporter, S component
MFFKFOBF_01092 0.0 - 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
MFFKFOBF_01093 4.99e-186 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MFFKFOBF_01094 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_01095 1.32e-130 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MFFKFOBF_01096 2.84e-205 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
MFFKFOBF_01097 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MFFKFOBF_01098 0.0 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-type transport system involved in multi-copper enzyme maturation permease component
MFFKFOBF_01099 1.27e-217 potA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MFFKFOBF_01100 2.53e-80 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MFFKFOBF_01106 9.01e-06 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MFFKFOBF_01107 1.2e-190 - 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
MFFKFOBF_01108 9.05e-62 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MFFKFOBF_01109 3.27e-184 - - - G - - - polysaccharide deacetylase
MFFKFOBF_01113 1.58e-63 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
MFFKFOBF_01115 4e-156 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MFFKFOBF_01116 1.05e-162 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MFFKFOBF_01117 2.12e-177 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MFFKFOBF_01118 1.85e-205 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MFFKFOBF_01119 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MFFKFOBF_01120 6.26e-101 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MFFKFOBF_01121 3.46e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MFFKFOBF_01122 1.79e-286 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MFFKFOBF_01123 1.53e-158 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MFFKFOBF_01124 5.44e-230 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MFFKFOBF_01125 1.31e-44 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFFKFOBF_01126 2.37e-222 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFFKFOBF_01127 1.05e-235 ydbI - - K - - - AI-2E family transporter
MFFKFOBF_01128 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MFFKFOBF_01129 3.59e-30 - - - - - - - -
MFFKFOBF_01130 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MFFKFOBF_01131 5e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MFFKFOBF_01132 2.42e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MFFKFOBF_01133 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MFFKFOBF_01134 2.28e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MFFKFOBF_01135 1.16e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MFFKFOBF_01136 3.64e-307 - - - S - - - Putative threonine/serine exporter
MFFKFOBF_01137 6.16e-282 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MFFKFOBF_01138 3.43e-277 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MFFKFOBF_01139 2.36e-248 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MFFKFOBF_01140 1.94e-63 - - - S - - - CRISPR-associated protein (Cas_Csn2)
MFFKFOBF_01141 3.84e-51 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MFFKFOBF_01142 5.57e-165 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MFFKFOBF_01143 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MFFKFOBF_01144 4.82e-293 sptS - - T - - - Histidine kinase
MFFKFOBF_01145 1.33e-150 dltr - - K - - - response regulator
MFFKFOBF_01146 1.25e-146 - - - T - - - Region found in RelA / SpoT proteins
MFFKFOBF_01147 4.1e-12 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein
MFFKFOBF_01149 6.26e-26 - - - - - - - -
MFFKFOBF_01151 1.33e-244 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MFFKFOBF_01152 1.54e-92 - - - - - - - -
MFFKFOBF_01153 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFFKFOBF_01154 2.61e-35 - - - - - - - -
MFFKFOBF_01155 4.59e-141 - - - K ko:K13928 - ko00000,ko03000 DNA-binding transcription factor activity
MFFKFOBF_01156 3.17e-12 - - - K - - - Transcriptional regulator, LysR family
MFFKFOBF_01157 8.59e-221 - - - K - - - LysR substrate binding domain
MFFKFOBF_01158 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MFFKFOBF_01159 1.96e-291 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MFFKFOBF_01160 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MFFKFOBF_01161 1.5e-311 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MFFKFOBF_01162 1.24e-279 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MFFKFOBF_01163 1.22e-139 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MFFKFOBF_01164 5.23e-06 mltD - - M ko:K08307 - ko00000,ko01000,ko01011 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MFFKFOBF_01165 1.58e-148 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MFFKFOBF_01166 4.13e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MFFKFOBF_01167 8.79e-136 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MFFKFOBF_01168 2.77e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MFFKFOBF_01169 5.25e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFFKFOBF_01170 8.85e-212 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MFFKFOBF_01171 4.38e-209 yitL - - S ko:K00243 - ko00000 S1 domain
MFFKFOBF_01172 6.91e-49 - - - I - - - Acyltransferase family
MFFKFOBF_01174 6.73e-50 ssuB - - P ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 anion transmembrane transporter activity
MFFKFOBF_01175 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MFFKFOBF_01176 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MFFKFOBF_01177 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MFFKFOBF_01178 2.87e-39 - - - S - - - Protein of unknown function (DUF2929)
MFFKFOBF_01179 3.38e-116 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MFFKFOBF_01180 6.64e-73 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MFFKFOBF_01181 3.93e-128 ywlG - - S - - - Belongs to the UPF0340 family
MFFKFOBF_01183 1.06e-82 - - - - - - - -
MFFKFOBF_01184 0.0 - - - L - - - SNF2 family N-terminal domain
MFFKFOBF_01185 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MFFKFOBF_01186 3.88e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MFFKFOBF_01187 7.34e-178 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFKFOBF_01188 4.62e-224 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MFFKFOBF_01189 0.0 oatA - - I - - - Acyltransferase
MFFKFOBF_01190 6.47e-298 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MFFKFOBF_01191 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MFFKFOBF_01192 6.15e-235 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
MFFKFOBF_01193 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MFFKFOBF_01194 3.95e-224 gyaR 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFFKFOBF_01195 3.71e-261 - - - S ko:K07045 - ko00000 Amidohydrolase
MFFKFOBF_01196 4.71e-283 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MFFKFOBF_01197 6.58e-101 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MFFKFOBF_01198 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MFFKFOBF_01199 3.61e-214 yvbU - - K - - - LysR substrate binding domain
MFFKFOBF_01200 1.15e-299 - - - EK - - - Aminotransferase, class I
MFFKFOBF_01201 1.67e-91 - - - E - - - Methionine synthase
MFFKFOBF_01202 1.51e-32 - - - K - - - LysR substrate binding domain
MFFKFOBF_01203 4.52e-57 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction enzyme, S subunit K01154
MFFKFOBF_01204 4.95e-217 - - - L - - - Belongs to the 'phage' integrase family
MFFKFOBF_01205 1.32e-89 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MFFKFOBF_01206 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MFFKFOBF_01207 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MFFKFOBF_01208 2.54e-102 - - - GM - - - NmrA-like family
MFFKFOBF_01209 2.2e-26 - - - S - - - Domain of unknown function (DUF4343)
MFFKFOBF_01210 5.94e-205 - - - T - - - Diguanylate cyclase, GGDEF domain
MFFKFOBF_01211 7.37e-99 - - - S ko:K07126 - ko00000 Sel1-like repeats.
MFFKFOBF_01212 6.23e-267 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MFFKFOBF_01213 3.46e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MFFKFOBF_01214 1.34e-243 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
MFFKFOBF_01215 1.58e-258 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MFFKFOBF_01216 3.97e-32 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MFFKFOBF_01217 3.04e-80 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MFFKFOBF_01218 2.71e-114 yfhC - - C - - - Nitroreductase family
MFFKFOBF_01219 2.41e-45 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MFFKFOBF_01220 4.71e-148 pgm1 - - G - - - phosphoglycerate mutase
MFFKFOBF_01221 2.04e-234 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MFFKFOBF_01222 1.67e-242 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFFKFOBF_01223 7.87e-213 - - - EG - - - EamA-like transporter family
MFFKFOBF_01224 6.87e-236 - - - - - - - -
MFFKFOBF_01225 9.82e-202 - - - S - - - EDD domain protein, DegV family
MFFKFOBF_01226 0.0 FbpA - - K - - - Fibronectin-binding protein
MFFKFOBF_01227 1.39e-313 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MFFKFOBF_01228 4.02e-58 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MFFKFOBF_01229 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MFFKFOBF_01230 1.88e-251 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MFFKFOBF_01231 7.92e-218 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MFFKFOBF_01232 1.3e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MFFKFOBF_01233 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MFFKFOBF_01234 3.03e-76 - - - - - - - -
MFFKFOBF_01235 1.02e-234 XK27_01810 - - S - - - Calcineurin-like phosphoesterase
MFFKFOBF_01236 1.01e-278 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MFFKFOBF_01237 5.35e-85 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MFFKFOBF_01238 8.99e-138 ypsA - - S - - - Belongs to the UPF0398 family
MFFKFOBF_01239 6.44e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MFFKFOBF_01240 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MFFKFOBF_01241 0.0 yuxL 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
MFFKFOBF_01242 6.48e-243 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFFKFOBF_01243 3.82e-77 - - - I - - - acetylesterase activity
MFFKFOBF_01244 4.46e-92 - - - I - - - Psort location Cytoplasmic, score
MFFKFOBF_01245 4.33e-192 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MFFKFOBF_01246 4.71e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MFFKFOBF_01247 1.24e-147 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MFFKFOBF_01248 1.58e-279 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MFFKFOBF_01249 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFFKFOBF_01250 1.38e-85 - - - - - - - -
MFFKFOBF_01251 1.12e-178 - - - - - - - -
MFFKFOBF_01252 1.16e-118 - - - - - - - -
MFFKFOBF_01253 2.31e-140 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MFFKFOBF_01254 5.48e-135 - - - - - - - -
MFFKFOBF_01255 1.05e-147 - - - - - - - -
MFFKFOBF_01256 3.79e-119 - - - - - - - -
MFFKFOBF_01257 5.82e-45 XK27_08850 - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
MFFKFOBF_01258 0.0 eriC - - P ko:K03281 - ko00000 chloride
MFFKFOBF_01259 3.14e-293 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MFFKFOBF_01260 8.7e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_01261 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFKFOBF_01262 8.05e-166 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MFFKFOBF_01263 6.66e-159 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MFFKFOBF_01264 1.68e-43 - - - - - - - -
MFFKFOBF_01265 2.95e-78 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MFFKFOBF_01267 1.1e-44 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MFFKFOBF_01268 1.84e-70 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
MFFKFOBF_01269 4.81e-73 - - - L - - - transposase activity
MFFKFOBF_01270 6.54e-157 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MFFKFOBF_01271 1.78e-202 - - - S - - - Aldo/keto reductase family
MFFKFOBF_01273 1.51e-26 - - - EGP - - - Major Facilitator
MFFKFOBF_01274 2.98e-220 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MFFKFOBF_01275 3.73e-263 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MFFKFOBF_01276 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MFFKFOBF_01277 1.82e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
MFFKFOBF_01278 6.53e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
MFFKFOBF_01279 4.45e-96 - - - S - - - Domain of unknown function (DUF4352)
MFFKFOBF_01280 1.4e-239 pkn2 - - KLT - - - Protein tyrosine kinase
MFFKFOBF_01281 4.89e-88 - - - S - - - Psort location Cytoplasmic, score
MFFKFOBF_01283 2.76e-248 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
MFFKFOBF_01284 4.18e-238 - - - S - - - DUF218 domain
MFFKFOBF_01285 3.3e-158 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFFKFOBF_01286 4.84e-258 napA - - P - - - Sodium/hydrogen exchanger family
MFFKFOBF_01287 0.0 cadA - - P - - - P-type ATPase
MFFKFOBF_01288 4.46e-54 ykuL - - S - - - (CBS) domain
MFFKFOBF_01289 2.9e-39 ykuL - - S - - - (CBS) domain
MFFKFOBF_01290 3.7e-82 - - - L - - - An automated process has identified a potential problem with this gene model
MFFKFOBF_01291 2.26e-287 - - - S - - - Membrane
MFFKFOBF_01292 3.16e-64 - - - - - - - -
MFFKFOBF_01293 0.000158 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MFFKFOBF_01294 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFKFOBF_01295 1.36e-308 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MFFKFOBF_01296 1.12e-49 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFKFOBF_01297 5.44e-315 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MFFKFOBF_01298 1.01e-86 - - - S - - - Iron-sulphur cluster biosynthesis
MFFKFOBF_01299 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_01300 5.09e-148 - - - K - - - Bacterial regulatory proteins, tetR family
MFFKFOBF_01302 6.94e-71 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_01303 6.17e-41 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_01304 2.5e-122 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_01305 1.48e-38 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFFKFOBF_01306 2.26e-49 - - - - - - - -
MFFKFOBF_01307 6.48e-76 - - - T - - - Putative diguanylate phosphodiesterase
MFFKFOBF_01310 8.71e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MFFKFOBF_01311 5.27e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MFFKFOBF_01312 1.19e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MFFKFOBF_01313 3.69e-181 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFFKFOBF_01314 1.98e-147 - - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MFFKFOBF_01315 2.5e-161 phoB - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MFFKFOBF_01316 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFKFOBF_01317 9.63e-52 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MFFKFOBF_01318 2.86e-05 - - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 pfam abc
MFFKFOBF_01319 8.06e-59 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MFFKFOBF_01321 1.84e-155 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MFFKFOBF_01322 1.17e-245 - - - S - - - Glycosyl hydrolases family 18
MFFKFOBF_01323 1.13e-131 M1-740 - - I - - - NUDIX domain
MFFKFOBF_01324 2.92e-172 - - - S - - - C4-dicarboxylate anaerobic carrier
MFFKFOBF_01325 2.21e-179 - - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MFFKFOBF_01326 1.23e-189 - - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MFFKFOBF_01327 8.58e-174 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MFFKFOBF_01328 1.43e-135 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
MFFKFOBF_01329 1.43e-63 - - - T - - - Putative diguanylate phosphodiesterase
MFFKFOBF_01330 7.1e-258 - - - T - - - Putative diguanylate phosphodiesterase
MFFKFOBF_01331 3.11e-196 - - - T - - - diguanylate cyclase
MFFKFOBF_01332 4.38e-34 - - - T - - - diguanylate cyclase
MFFKFOBF_01333 2.98e-135 - - - - - - - -
MFFKFOBF_01334 2.61e-193 - - - G - - - Sucrose-6F-phosphate phosphohydrolase
MFFKFOBF_01335 1.6e-12 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFFKFOBF_01336 7.52e-47 - - - V ko:K06147 - ko00000,ko02000 (ABC) transporter
MFFKFOBF_01337 6.33e-50 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_01338 1.05e-68 - - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
MFFKFOBF_01339 1.2e-215 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MFFKFOBF_01340 3.97e-38 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MFFKFOBF_01341 7.44e-143 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MFFKFOBF_01342 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFFKFOBF_01343 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFFKFOBF_01344 2.02e-219 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MFFKFOBF_01345 9.25e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MFFKFOBF_01346 5.48e-260 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MFFKFOBF_01347 8.27e-223 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MFFKFOBF_01348 2.02e-215 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
MFFKFOBF_01349 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MFFKFOBF_01350 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MFFKFOBF_01351 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MFFKFOBF_01352 4.66e-93 ypmB - - S - - - Protein conserved in bacteria
MFFKFOBF_01353 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MFFKFOBF_01354 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MFFKFOBF_01355 2.21e-196 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFFKFOBF_01356 1.48e-82 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MFFKFOBF_01357 6.59e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MFFKFOBF_01358 1.7e-313 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MFFKFOBF_01359 9.76e-257 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MFFKFOBF_01360 2.22e-50 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MFFKFOBF_01361 2.02e-268 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MFFKFOBF_01362 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFFKFOBF_01363 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFFKFOBF_01364 1.21e-63 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MFFKFOBF_01365 1.79e-126 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MFFKFOBF_01366 1.61e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MFFKFOBF_01367 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MFFKFOBF_01368 6.68e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MFFKFOBF_01369 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MFFKFOBF_01370 1.71e-287 - - - S - - - Protein of unknown function (DUF2974)
MFFKFOBF_01371 0.0 - - - V - - - ATPases associated with a variety of cellular activities
MFFKFOBF_01372 4.46e-90 - - - - - - - -
MFFKFOBF_01374 4.6e-157 - - - S ko:K07507 - ko00000,ko02000 MgtC family
MFFKFOBF_01376 2.4e-95 - - - K - - - Helix-turn-helix XRE-family like proteins
MFFKFOBF_01377 1.86e-185 - - - V - - - ABC transporter transmembrane region
MFFKFOBF_01378 6.57e-179 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MFFKFOBF_01379 1.66e-202 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MFFKFOBF_01380 1.23e-17 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MFFKFOBF_01382 1.21e-33 - - - - - - - -
MFFKFOBF_01383 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K06147,ko:K11085,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MFFKFOBF_01384 0.0 - - - KLT - - - Protein kinase domain
MFFKFOBF_01385 6.96e-30 - - - - - - - -
MFFKFOBF_01387 2.7e-145 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_01388 5.36e-171 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MFFKFOBF_01390 0.0 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MFFKFOBF_01391 2.85e-15 - - - K - - - Acetyltransferase (GNAT) domain
MFFKFOBF_01392 8.13e-38 - - - K - - - Acetyltransferase (GNAT) domain
MFFKFOBF_01393 3.56e-196 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MFFKFOBF_01394 1.31e-116 - - - S - - - ECF-type riboflavin transporter, S component
MFFKFOBF_01395 0.0 - - - L - - - Helicase C-terminal domain protein
MFFKFOBF_01396 7.61e-133 - - - T - - - integral membrane protein
MFFKFOBF_01397 1.33e-110 - - - S - - - YcxB-like protein
MFFKFOBF_01398 1.89e-95 ywnA - - K - - - Transcriptional regulator
MFFKFOBF_01399 6.01e-45 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 epimerase
MFFKFOBF_01400 2.33e-75 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
MFFKFOBF_01401 3.62e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MFFKFOBF_01403 3.68e-190 - - - T - - - Putative diguanylate phosphodiesterase
MFFKFOBF_01404 3.18e-88 - - - T - - - domain protein
MFFKFOBF_01405 4.02e-237 - - - M - - - Glycosyl transferase family 8
MFFKFOBF_01406 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MFFKFOBF_01407 4.45e-128 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MFFKFOBF_01408 7.39e-65 - - - - - - - -
MFFKFOBF_01409 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MFFKFOBF_01411 2.76e-82 - - - V - - - AAA domain (dynein-related subfamily)
MFFKFOBF_01412 6.16e-165 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 PFAM C-5 cytosine-specific DNA methylase
MFFKFOBF_01413 1.62e-143 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 PFAM C-5 cytosine-specific DNA methylase
MFFKFOBF_01414 1.02e-14 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MFFKFOBF_01415 6.11e-152 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MFFKFOBF_01417 3.75e-84 - - - - - - - -
MFFKFOBF_01418 8.07e-54 - - - - - - - -
MFFKFOBF_01419 1.51e-153 - - - - - - - -
MFFKFOBF_01420 1.64e-241 - - - S - - - GTP binding
MFFKFOBF_01421 9.2e-48 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MFFKFOBF_01422 1.56e-61 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MFFKFOBF_01423 1.77e-71 - - - O - - - Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
MFFKFOBF_01424 2.71e-233 - - - S - - - AAA domain
MFFKFOBF_01425 8.76e-104 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MFFKFOBF_01426 2.61e-161 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MFFKFOBF_01427 8.57e-41 - - - - - - - -
MFFKFOBF_01428 2.88e-39 - - - - - - - -
MFFKFOBF_01429 5.92e-165 - - - G - - - Belongs to the phosphoglycerate mutase family
MFFKFOBF_01430 1.49e-157 - - - S ko:K07090 - ko00000 membrane transporter protein
MFFKFOBF_01431 7.93e-140 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MFFKFOBF_01432 7.52e-121 - - - K - - - Acetyltransferase (GNAT) family
MFFKFOBF_01433 3.74e-206 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MFFKFOBF_01434 6.75e-28 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MFFKFOBF_01435 4.07e-50 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase
MFFKFOBF_01436 9.02e-177 - - - K - - - Helix-turn-helix domain, rpiR family
MFFKFOBF_01437 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MFFKFOBF_01438 1.25e-61 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MFFKFOBF_01439 7.97e-209 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MFFKFOBF_01440 3.01e-11 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
MFFKFOBF_01441 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
MFFKFOBF_01442 7.78e-164 - - - D - - - nuclear chromosome segregation
MFFKFOBF_01443 1.91e-08 - - - D - - - nuclear chromosome segregation
MFFKFOBF_01444 3.82e-118 - - - M - - - LysM domain protein
MFFKFOBF_01447 8.07e-155 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MFFKFOBF_01448 0.0 bmr3_1 - - EGP ko:K18935 - ko00000,ko02000 Sugar (and other) transporter
MFFKFOBF_01449 2.82e-279 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MFFKFOBF_01453 1.15e-126 - 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MFFKFOBF_01454 1.03e-135 yiiE - - S - - - Protein of unknown function (DUF1211)
MFFKFOBF_01455 3.18e-34 - - - - - - - -
MFFKFOBF_01456 6.96e-187 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MFFKFOBF_01457 2.93e-69 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MFFKFOBF_01458 1.31e-101 - 2.7.1.211 - G ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MFFKFOBF_01459 2.69e-255 - 2.7.1.11, 2.7.1.90 - F ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MFFKFOBF_01460 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MFFKFOBF_01461 1.66e-160 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MFFKFOBF_01462 8.4e-31 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MFFKFOBF_01464 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MFFKFOBF_01465 0.0 - - - E - - - Amino acid permease
MFFKFOBF_01466 3.24e-141 - - - L - - - Transposase and inactivated derivatives, IS30 family
MFFKFOBF_01467 1.37e-259 - - - G - - - Major Facilitator Superfamily
MFFKFOBF_01468 3.21e-48 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
MFFKFOBF_01469 1.09e-263 - - - G - - - Major Facilitator Superfamily
MFFKFOBF_01470 6.37e-258 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
MFFKFOBF_01472 1.08e-247 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
MFFKFOBF_01473 2.42e-282 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
MFFKFOBF_01476 3.39e-63 - - - - - - - -
MFFKFOBF_01477 0.0 - - - L - - - Helicase conserved C-terminal domain
MFFKFOBF_01478 4.74e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MFFKFOBF_01479 4.15e-10 - - - K - - - Helix-turn-helix domain
MFFKFOBF_01481 1.16e-207 - 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
MFFKFOBF_01482 4.66e-312 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MFFKFOBF_01483 9.44e-08 - - - - - - - -
MFFKFOBF_01484 1.64e-83 - - - S - - - Domain of unknown function (DUF956)
MFFKFOBF_01485 2.27e-217 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MFFKFOBF_01486 8.56e-180 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MFFKFOBF_01487 9.5e-239 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MFFKFOBF_01489 1.27e-187 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
MFFKFOBF_01490 6.27e-126 XK27_07735 - - S - - - YjbR
MFFKFOBF_01491 1.56e-180 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
MFFKFOBF_01492 6.43e-51 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MFFKFOBF_01493 5.41e-69 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MFFKFOBF_01494 3.51e-166 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
MFFKFOBF_01495 0.0 - - - L - - - Type III restriction enzyme, res subunit
MFFKFOBF_01496 6.95e-12 - - - D - - - Filamentation induced by cAMP protein fic
MFFKFOBF_01498 1.3e-200 - - - V - - - LD-carboxypeptidase
MFFKFOBF_01499 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MFFKFOBF_01500 4.07e-221 - - - - - - - -
MFFKFOBF_01501 3.04e-177 - - - - - - - -
MFFKFOBF_01502 4.3e-36 - - - - - - - -
MFFKFOBF_01503 4.05e-147 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MFFKFOBF_01504 5.87e-177 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
MFFKFOBF_01505 2.71e-44 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MFFKFOBF_01506 4.54e-45 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MFFKFOBF_01507 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MFFKFOBF_01508 0.0 - - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MFFKFOBF_01509 1.73e-218 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_01510 1.98e-100 ywnA - - K - - - Transcriptional regulator
MFFKFOBF_01511 9.4e-121 - - - GM - - - NmrA-like family
MFFKFOBF_01512 2.16e-210 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Peptidase family M48
MFFKFOBF_01513 1.12e-290 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MFFKFOBF_01514 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MFFKFOBF_01515 3.89e-101 - - - K - - - GNAT family
MFFKFOBF_01516 3.23e-96 - - - - - - - -
MFFKFOBF_01517 1.77e-137 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
MFFKFOBF_01518 5.84e-253 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MFFKFOBF_01519 2.71e-73 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
MFFKFOBF_01520 5.37e-59 - - - EGP - - - Major facilitator Superfamily
MFFKFOBF_01521 3.61e-89 - - - EGP - - - Major Facilitator
MFFKFOBF_01522 1.08e-47 - - - EGP - - - Major Facilitator
MFFKFOBF_01523 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFFKFOBF_01524 2.53e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MFFKFOBF_01525 1.03e-131 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MFFKFOBF_01526 1.57e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MFFKFOBF_01527 5.47e-314 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
MFFKFOBF_01528 4.07e-217 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MFFKFOBF_01529 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFFKFOBF_01530 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
MFFKFOBF_01531 3.99e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MFFKFOBF_01532 1.37e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MFFKFOBF_01533 2.91e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MFFKFOBF_01534 1.16e-270 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MFFKFOBF_01535 1.58e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MFFKFOBF_01536 1.59e-141 yqeK - - H - - - Hydrolase, HD family
MFFKFOBF_01537 1.46e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MFFKFOBF_01538 1.68e-273 ylbM - - S - - - Belongs to the UPF0348 family
MFFKFOBF_01539 2.09e-130 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MFFKFOBF_01540 1.96e-164 csrR - - K - - - response regulator
MFFKFOBF_01541 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFKFOBF_01542 4.75e-202 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFFKFOBF_01543 2.2e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MFFKFOBF_01544 7.67e-175 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFFKFOBF_01545 9.83e-81 yodB - - K - - - Transcriptional regulator, HxlR family
MFFKFOBF_01546 4.12e-254 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MFFKFOBF_01547 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFFKFOBF_01548 2.55e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFFKFOBF_01549 1.26e-61 - - - L - - - Psort location Cytoplasmic, score
MFFKFOBF_01550 5.24e-130 - - - L - - - Transposase DDE domain
MFFKFOBF_01551 1.04e-41 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MFFKFOBF_01552 2.81e-120 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MFFKFOBF_01553 6.46e-94 csm5 - - L ko:K19140 - ko00000,ko02048 RAMP superfamily
MFFKFOBF_01554 6.35e-114 - - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
MFFKFOBF_01555 4.49e-103 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
MFFKFOBF_01556 3.69e-28 - - - L ko:K19138 - ko00000,ko02048 Pfam:DUF310
MFFKFOBF_01557 1.05e-236 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
MFFKFOBF_01559 4.39e-72 - - - S - - - Pfam:DUF2276
MFFKFOBF_01560 0.0 - - - - - - - -
MFFKFOBF_01561 0.0 - - - - - - - -
MFFKFOBF_01562 2.86e-78 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFFKFOBF_01563 1.22e-96 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFFKFOBF_01564 2.41e-101 - - - K - - - Transcriptional regulator, MarR family
MFFKFOBF_01565 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_01566 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
MFFKFOBF_01567 3.26e-68 XK27_05625 - - P - - - Rhodanese Homology Domain
MFFKFOBF_01568 1.87e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
MFFKFOBF_01569 1.22e-211 - - - L - - - Resolvase, N-terminal
MFFKFOBF_01570 2.09e-61 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFFKFOBF_01572 2.43e-55 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MFFKFOBF_01573 6.36e-171 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
MFFKFOBF_01574 2.06e-42 - - - K - - - LytTr DNA-binding domain protein
MFFKFOBF_01575 1.88e-78 - - - - - - - -
MFFKFOBF_01576 6.37e-76 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MFFKFOBF_01577 2.84e-44 - - - M - - - ErfK YbiS YcfS YnhG
MFFKFOBF_01578 9.99e-216 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MFFKFOBF_01579 7.86e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MFFKFOBF_01580 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MFFKFOBF_01581 1.29e-72 yheA - - S - - - Belongs to the UPF0342 family
MFFKFOBF_01582 5.14e-288 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MFFKFOBF_01583 0.0 yhaN - - L - - - AAA domain
MFFKFOBF_01584 1.28e-229 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MFFKFOBF_01585 2.12e-85 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 - F ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03000 shikimate kinase activity
MFFKFOBF_01586 1.01e-63 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MFFKFOBF_01587 8.28e-199 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MFFKFOBF_01588 2.62e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MFFKFOBF_01589 2.5e-173 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MFFKFOBF_01590 2.87e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MFFKFOBF_01591 1.4e-71 - - - - - - - -
MFFKFOBF_01592 1.67e-104 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MFFKFOBF_01593 3.02e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_01594 7.06e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MFFKFOBF_01595 4.69e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MFFKFOBF_01596 9.52e-72 ytpP - - CO - - - Thioredoxin
MFFKFOBF_01597 6.93e-154 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFFKFOBF_01598 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MFFKFOBF_01599 1.18e-141 - - - K - - - Helix-turn-helix domain
MFFKFOBF_01600 3.78e-85 - - - L - - - MobA MobL family protein
MFFKFOBF_01603 5.07e-282 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
MFFKFOBF_01604 1.06e-256 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MFFKFOBF_01605 7.66e-228 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MFFKFOBF_01606 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MFFKFOBF_01607 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MFFKFOBF_01608 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MFFKFOBF_01609 5.92e-102 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MFFKFOBF_01612 1.5e-276 - - - S - - - FtsX-like permease family
MFFKFOBF_01613 1.96e-154 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFKFOBF_01615 6.88e-26 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
MFFKFOBF_01616 4.26e-108 - - - - - - - -
MFFKFOBF_01617 5.72e-29 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MFFKFOBF_01618 1.25e-47 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MFFKFOBF_01619 5.06e-115 yjcF - - S - - - Acetyltransferase (GNAT) domain
MFFKFOBF_01620 1.14e-183 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MFFKFOBF_01621 2.93e-280 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MFFKFOBF_01622 1.08e-286 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MFFKFOBF_01623 2.66e-97 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MFFKFOBF_01624 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MFFKFOBF_01625 6.19e-97 cydD1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
MFFKFOBF_01628 2.87e-43 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 beta-glucosidase activity
MFFKFOBF_01629 7.01e-246 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MFFKFOBF_01630 3.6e-38 scrK 2.7.1.2, 2.7.1.4 - GK ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MFFKFOBF_01631 1.6e-56 yliE - - T - - - EAL domain
MFFKFOBF_01633 5.03e-180 - - - - - - - -
MFFKFOBF_01635 1.81e-109 - - - K - - - DNA-templated transcription, initiation
MFFKFOBF_01636 2.5e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MFFKFOBF_01637 2.41e-211 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
MFFKFOBF_01638 0.0 - - - S - - - Bacterial membrane protein, YfhO
MFFKFOBF_01639 6.42e-229 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 Glycosyltransferase like family 2
MFFKFOBF_01640 1.64e-120 - - - K - - - Domain of unknown function (DUF1836)
MFFKFOBF_01641 5.66e-187 yitS - - S - - - EDD domain protein, DegV family
MFFKFOBF_01642 9e-105 yliE - - T - - - EAL domain
MFFKFOBF_01643 9.22e-135 - - - E - - - GDSL-like Lipase/Acylhydrolase
MFFKFOBF_01644 1.92e-161 pgm7 - - G - - - Phosphoglycerate mutase family
MFFKFOBF_01645 1.79e-16 - - - - - - - -
MFFKFOBF_01646 6.26e-139 - - - - - - - -
MFFKFOBF_01647 1.6e-115 - - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin transmembrane transporter activity
MFFKFOBF_01648 2.64e-103 - - - S - - - VanZ like family
MFFKFOBF_01649 4.46e-94 gtcA - - S - - - Teichoic acid glycosylation protein
MFFKFOBF_01650 1.01e-165 - - - S - - - VanZ like family
MFFKFOBF_01651 2.93e-38 - - - L - - - DNA synthesis involved in DNA repair
MFFKFOBF_01652 3.23e-85 - - - L - - - DNA synthesis involved in DNA repair
MFFKFOBF_01653 1.18e-42 - - - L - - - DNA synthesis involved in DNA repair
MFFKFOBF_01655 4.12e-310 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphodiester phosphodiesterase activity
MFFKFOBF_01657 5.55e-54 - - - - - - - -
MFFKFOBF_01658 1.11e-171 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MFFKFOBF_01659 1.11e-160 gpm2 - - G - - - Phosphoglycerate mutase family
MFFKFOBF_01660 2.58e-147 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MFFKFOBF_01661 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MFFKFOBF_01662 8.3e-40 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MFFKFOBF_01663 1.43e-91 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MFFKFOBF_01665 8.21e-97 - - - K - - - LytTr DNA-binding domain
MFFKFOBF_01666 4.26e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
MFFKFOBF_01667 8.26e-220 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MFFKFOBF_01668 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFFKFOBF_01669 1.34e-100 - - - S - - - Helix-turn-helix domain
MFFKFOBF_01670 1.24e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MFFKFOBF_01671 3.13e-252 - - - - - - - -
MFFKFOBF_01672 2.11e-99 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
MFFKFOBF_01673 3.17e-111 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
MFFKFOBF_01674 3.99e-231 licD - - M ko:K07271 - ko00000,ko01000 LicD family
MFFKFOBF_01675 0.0 epsIIL - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MFFKFOBF_01677 7.51e-190 - - - M - - - Domain of unknown function (DUF4422)
MFFKFOBF_01678 3.63e-271 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MFFKFOBF_01679 2.66e-219 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MFFKFOBF_01680 1.15e-63 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MFFKFOBF_01681 6.87e-99 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MFFKFOBF_01682 1.19e-280 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MFFKFOBF_01683 8.77e-192 cps3J - - M - - - Domain of unknown function (DUF4422)
MFFKFOBF_01684 3.11e-152 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MFFKFOBF_01685 1.03e-118 - - - S - - - Core-2/I-Branching enzyme
MFFKFOBF_01687 2.62e-246 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MFFKFOBF_01689 1.79e-95 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MFFKFOBF_01690 3.12e-50 - - - - - - - -
MFFKFOBF_01691 8.87e-36 - - - - - - - -
MFFKFOBF_01692 2.34e-69 - - - K - - - sequence-specific DNA binding
MFFKFOBF_01693 3.04e-234 - 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Rossmann-like domain
MFFKFOBF_01694 2.91e-61 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MFFKFOBF_01695 6.07e-114 - - - S - - - SLAP domain
MFFKFOBF_01696 8e-136 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MFFKFOBF_01698 1.51e-47 - - - S - - - Psort location CytoplasmicMembrane, score
MFFKFOBF_01699 1.92e-108 cylB - - U ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MFFKFOBF_01700 2.57e-138 - - - L - - - Integrase
MFFKFOBF_01701 1.15e-95 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MFFKFOBF_01702 1.01e-95 - - - K - - - 3.5.2 Transcription regulation
MFFKFOBF_01703 6.06e-276 - - - V - - - drug transmembrane transporter activity
MFFKFOBF_01705 1.14e-48 - - - T - - - diguanylate cyclase activity
MFFKFOBF_01706 1.29e-257 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MFFKFOBF_01707 0.0 carB - - F - - - Psort location Cytoplasmic, score 8.87
MFFKFOBF_01708 1.03e-41 - - - V ko:K06147 - ko00000,ko02000 (ABC) transporter
MFFKFOBF_01709 2.09e-121 ybaJ - - Q - - - Hypothetical methyltransferase
MFFKFOBF_01710 7.57e-10 - - - Q - - - Methyltransferase domain
MFFKFOBF_01711 2.4e-284 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MFFKFOBF_01712 5.89e-148 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
MFFKFOBF_01714 4.81e-48 - - - L - - - DDE superfamily endonuclease
MFFKFOBF_01715 0.0 - - - V - - - ABC transporter transmembrane region
MFFKFOBF_01716 2.39e-12 - - - S - - - PAS domain
MFFKFOBF_01717 6.54e-105 - - - GK - - - ROK family
MFFKFOBF_01719 2.07e-199 dkgB - - S - - - reductase
MFFKFOBF_01720 1.23e-173 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MFFKFOBF_01721 1.19e-56 - - - E ko:K08659 - ko00000,ko01000,ko01002 dipeptidase activity
MFFKFOBF_01722 2.09e-136 - - - - - - - -
MFFKFOBF_01723 3.4e-106 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MFFKFOBF_01724 8.62e-222 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MFFKFOBF_01725 8.44e-209 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MFFKFOBF_01726 6.87e-203 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MFFKFOBF_01727 4.44e-36 - - - - - - - -
MFFKFOBF_01728 9.52e-128 yobS - - K - - - Bacterial regulatory proteins, tetR family
MFFKFOBF_01729 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MFFKFOBF_01730 2.73e-228 - - - - - - - -
MFFKFOBF_01731 0.0 - - - S - - - membrane
MFFKFOBF_01732 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MFFKFOBF_01733 2.18e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MFFKFOBF_01734 4.78e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MFFKFOBF_01735 6.54e-147 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
MFFKFOBF_01736 2.98e-45 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MFFKFOBF_01737 8.9e-92 yqhL - - P - - - Rhodanese-like protein
MFFKFOBF_01738 1.87e-218 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MFFKFOBF_01739 7.49e-216 ynbB - - P - - - aluminum resistance
MFFKFOBF_01740 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MFFKFOBF_01741 8.7e-278 - - - EGP - - - Major Facilitator Superfamily
MFFKFOBF_01742 1.47e-83 - - - S - - - Domain of unknown function DUF1828
MFFKFOBF_01743 2.65e-228 - - - - - - - -
MFFKFOBF_01744 4.88e-88 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MFFKFOBF_01745 9.16e-69 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MFFKFOBF_01746 4.34e-199 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MFFKFOBF_01747 4.14e-142 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MFFKFOBF_01748 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MFFKFOBF_01749 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MFFKFOBF_01750 4.45e-100 - - - L - - - Transposase and inactivated derivatives, IS30 family
MFFKFOBF_01751 1.41e-33 - - - L - - - DDE superfamily endonuclease
MFFKFOBF_01752 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MFFKFOBF_01753 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MFFKFOBF_01754 6.41e-148 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MFFKFOBF_01755 3.71e-285 - - - L - - - Transposase
MFFKFOBF_01756 9.48e-165 - - - F - - - glutamine amidotransferase
MFFKFOBF_01757 1.32e-122 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
MFFKFOBF_01758 1.15e-201 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MFFKFOBF_01759 5.27e-193 - - - I - - - alpha/beta hydrolase fold
MFFKFOBF_01760 2.44e-136 - - - S - - - SNARE associated Golgi protein
MFFKFOBF_01761 1.95e-119 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MFFKFOBF_01762 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MFFKFOBF_01763 1.13e-127 - - - K ko:K03088 - ko00000,ko03021 Sigma-70 region 2
MFFKFOBF_01764 2.05e-196 - - - S - - - Protein of unknown function (DUF3298)
MFFKFOBF_01765 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
MFFKFOBF_01766 2.09e-208 yvgN - - C - - - Aldo keto reductase
MFFKFOBF_01767 2.11e-221 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MFFKFOBF_01768 8.99e-104 - - - - - - - -
MFFKFOBF_01769 3.75e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MFFKFOBF_01770 1.19e-17 - - - S - - - glycolate biosynthetic process
MFFKFOBF_01771 6.88e-24 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
MFFKFOBF_01772 7.2e-176 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MFFKFOBF_01773 1.11e-25 - - - L - - - transposase and inactivated derivatives, IS30 family
MFFKFOBF_01774 1.48e-307 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFFKFOBF_01775 9.6e-213 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MFFKFOBF_01776 1.1e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MFFKFOBF_01777 3.99e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MFFKFOBF_01778 1.82e-202 yicL - - EG - - - EamA-like transporter family
MFFKFOBF_01779 1.06e-63 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MFFKFOBF_01780 7.26e-39 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
MFFKFOBF_01782 8.22e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MFFKFOBF_01783 1.88e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MFFKFOBF_01784 6.31e-260 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MFFKFOBF_01785 1.16e-239 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MFFKFOBF_01786 1.37e-75 - - - - - - - -
MFFKFOBF_01787 4.29e-148 - - - L - - - DDE superfamily endonuclease
MFFKFOBF_01788 8.22e-138 - - - L - - - DDE superfamily endonuclease
MFFKFOBF_01789 2.16e-52 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MFFKFOBF_01790 4.02e-116 - 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
MFFKFOBF_01792 7.15e-295 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MFFKFOBF_01793 1.34e-201 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MFFKFOBF_01794 0.0 - - - M - - - ErfK YbiS YcfS YnhG
MFFKFOBF_01796 2.16e-07 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MFFKFOBF_01798 1.21e-258 - - - S - - - amidohydrolase
MFFKFOBF_01799 5.61e-10 XK27_07210 - - S - - - B3 4 domain
MFFKFOBF_01800 4.34e-63 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MFFKFOBF_01801 3.52e-228 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MFFKFOBF_01819 2.13e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MFFKFOBF_01820 3.01e-196 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MFFKFOBF_01821 2.48e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MFFKFOBF_01822 1.12e-39 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MFFKFOBF_01823 3.43e-27 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MFFKFOBF_01824 7.31e-41 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MFFKFOBF_01825 7.25e-240 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFFKFOBF_01826 2.11e-99 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
MFFKFOBF_01833 3.57e-72 - 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 MafB19-like deaminase
MFFKFOBF_01834 6.76e-16 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MFFKFOBF_01835 2.86e-253 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MFFKFOBF_01836 1.85e-48 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MFFKFOBF_01837 2.58e-33 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MFFKFOBF_01838 4.14e-166 - - - K - - - LysR family
MFFKFOBF_01839 5.52e-207 - - - J - - - Methyltransferase
MFFKFOBF_01840 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Aluminium induced protein
MFFKFOBF_01849 3.72e-203 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MFFKFOBF_01850 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MFFKFOBF_01852 1.39e-310 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MFFKFOBF_01853 6.73e-72 luxA_2 - - C - - - Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
MFFKFOBF_01854 1.19e-48 - - - T - - - CHASE
MFFKFOBF_01855 4.59e-127 - - - S - - - Cob(I)alamin adenosyltransferase
MFFKFOBF_01856 5.84e-123 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
MFFKFOBF_01858 5.43e-97 - - - - - - - -
MFFKFOBF_01859 9.98e-170 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MFFKFOBF_01860 3.85e-316 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MFFKFOBF_01861 1.2e-169 - - - L - - - COG3547 Transposase and inactivated derivatives

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)