ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GEMNEGCL_00001 1.44e-62 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GEMNEGCL_00002 3.71e-163 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GEMNEGCL_00003 1.17e-87 - - - GM - - - NAD(P)H-binding
GEMNEGCL_00004 1.59e-44 - - - S - - - Domain of unknown function (DUF4440)
GEMNEGCL_00005 3.49e-113 - - - K - - - LysR substrate binding domain
GEMNEGCL_00007 2.25e-57 - - - K - - - Tetracycline repressor, C-terminal all-alpha domain
GEMNEGCL_00008 5.94e-100 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
GEMNEGCL_00010 1.09e-46 - - - - - - - -
GEMNEGCL_00011 1.24e-75 - - - S - - - Peptidase propeptide and YPEB domain
GEMNEGCL_00012 1.48e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GEMNEGCL_00013 7.92e-218 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GEMNEGCL_00014 1.88e-125 - - - E - - - GDSL-like Lipase/Acylhydrolase
GEMNEGCL_00015 1.36e-96 yjcF - - S - - - Acetyltransferase (GNAT) domain
GEMNEGCL_00016 7.09e-184 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_00017 6.89e-136 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
GEMNEGCL_00018 3e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GEMNEGCL_00019 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GEMNEGCL_00020 9.95e-157 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
GEMNEGCL_00021 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
GEMNEGCL_00022 1.87e-308 - - - S - - - response to antibiotic
GEMNEGCL_00023 2.7e-162 - - - - - - - -
GEMNEGCL_00024 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GEMNEGCL_00025 7.34e-86 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
GEMNEGCL_00026 1.42e-57 - - - - - - - -
GEMNEGCL_00027 4.65e-14 - - - - - - - -
GEMNEGCL_00028 1.29e-27 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
GEMNEGCL_00029 3.22e-185 - - - K - - - rpiR family
GEMNEGCL_00030 5.06e-237 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GEMNEGCL_00031 2.47e-223 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Beta-lactamase
GEMNEGCL_00032 1.54e-194 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GEMNEGCL_00033 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GEMNEGCL_00034 5.03e-313 mdr - - EGP - - - Major Facilitator
GEMNEGCL_00035 1.72e-285 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GEMNEGCL_00038 1.13e-136 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GEMNEGCL_00039 2.36e-29 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
GEMNEGCL_00040 1.08e-217 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GEMNEGCL_00041 9.29e-51 - - - S - - - Protein of unknown function (DUF3021)
GEMNEGCL_00042 8.95e-70 - - - K - - - LytTr DNA-binding domain
GEMNEGCL_00045 1.75e-164 - - - M - - - Rib/alpha-like repeat
GEMNEGCL_00046 2.31e-277 yqjV - - EGP - - - Major Facilitator Superfamily
GEMNEGCL_00047 2.19e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GEMNEGCL_00048 3.41e-132 yitW - - S - - - Iron-sulfur cluster assembly protein
GEMNEGCL_00049 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GEMNEGCL_00050 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
GEMNEGCL_00051 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
GEMNEGCL_00052 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GEMNEGCL_00053 0.0 - - - S - - - Calcineurin-like phosphoesterase
GEMNEGCL_00054 5.18e-109 - - - - - - - -
GEMNEGCL_00055 5.61e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
GEMNEGCL_00056 1.81e-31 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00057 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GEMNEGCL_00058 3.56e-281 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GEMNEGCL_00059 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
GEMNEGCL_00060 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
GEMNEGCL_00061 1.48e-210 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GEMNEGCL_00062 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
GEMNEGCL_00063 4.35e-185 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
GEMNEGCL_00064 4.71e-239 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GEMNEGCL_00065 4.05e-209 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
GEMNEGCL_00066 5.55e-137 - - - K - - - Transcriptional regulator, AbiEi antitoxin
GEMNEGCL_00067 4.05e-242 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
GEMNEGCL_00068 7.61e-42 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
GEMNEGCL_00069 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
GEMNEGCL_00070 2.65e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GEMNEGCL_00071 3.37e-192 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GEMNEGCL_00072 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GEMNEGCL_00073 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GEMNEGCL_00074 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
GEMNEGCL_00075 2.42e-40 - - - - - - - -
GEMNEGCL_00076 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GEMNEGCL_00077 0.0 eriC - - P ko:K03281 - ko00000 chloride
GEMNEGCL_00078 1.21e-42 - - - E - - - Zn peptidase
GEMNEGCL_00079 8.29e-76 - - - K - - - Helix-turn-helix XRE-family like proteins
GEMNEGCL_00080 4.75e-58 - - - - - - - -
GEMNEGCL_00081 4.54e-135 - - - S - - - Bacteriocin helveticin-J
GEMNEGCL_00082 1.14e-154 - - - S - - - SLAP domain
GEMNEGCL_00083 6.57e-175 - - - S - - - SLAP domain
GEMNEGCL_00084 3.91e-269 - - - - - - - -
GEMNEGCL_00085 6.46e-27 - - - - - - - -
GEMNEGCL_00086 1.83e-316 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
GEMNEGCL_00087 3.14e-137 - - - - - - - -
GEMNEGCL_00088 6.63e-147 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
GEMNEGCL_00089 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GEMNEGCL_00090 3.27e-58 - - - S - - - Cupredoxin-like domain
GEMNEGCL_00091 5.94e-75 - - - S - - - Cupredoxin-like domain
GEMNEGCL_00092 3.15e-48 - - - - - - - -
GEMNEGCL_00096 2.27e-179 - - - - - - - -
GEMNEGCL_00097 0.0 - - - V - - - ABC transporter transmembrane region
GEMNEGCL_00098 7.23e-50 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GEMNEGCL_00099 4.76e-168 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
GEMNEGCL_00100 3.16e-144 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_00101 0.0 - - - S - - - SH3-like domain
GEMNEGCL_00102 1.16e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GEMNEGCL_00103 8.59e-221 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GEMNEGCL_00104 2.78e-251 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GEMNEGCL_00105 2.44e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GEMNEGCL_00106 1.55e-117 - - - S - - - Short repeat of unknown function (DUF308)
GEMNEGCL_00107 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GEMNEGCL_00108 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GEMNEGCL_00109 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GEMNEGCL_00110 3.42e-232 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GEMNEGCL_00111 3.31e-239 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GEMNEGCL_00112 4.04e-203 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GEMNEGCL_00113 3.54e-230 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GEMNEGCL_00114 8.33e-27 - - - - - - - -
GEMNEGCL_00115 4.17e-236 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GEMNEGCL_00116 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GEMNEGCL_00117 1.55e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GEMNEGCL_00118 9.44e-169 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
GEMNEGCL_00119 2.68e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
GEMNEGCL_00120 5.04e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
GEMNEGCL_00121 1.94e-268 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
GEMNEGCL_00122 3.03e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GEMNEGCL_00123 1.17e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GEMNEGCL_00124 3.92e-123 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GEMNEGCL_00125 2.13e-152 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
GEMNEGCL_00126 1.39e-171 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
GEMNEGCL_00127 5.49e-301 ymfH - - S - - - Peptidase M16
GEMNEGCL_00128 1.47e-284 ymfF - - S - - - Peptidase M16 inactive domain protein
GEMNEGCL_00129 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GEMNEGCL_00130 3.12e-91 - - - S - - - Protein of unknown function (DUF1149)
GEMNEGCL_00131 2.12e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GEMNEGCL_00132 2.19e-270 XK27_05220 - - S - - - AI-2E family transporter
GEMNEGCL_00133 1.99e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
GEMNEGCL_00134 1.01e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GEMNEGCL_00135 4.52e-237 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GEMNEGCL_00136 4.86e-150 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
GEMNEGCL_00137 2.15e-137 - - - S - - - Protein of unknown function (DUF1461)
GEMNEGCL_00138 1.1e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GEMNEGCL_00139 6.48e-136 yutD - - S - - - Protein of unknown function (DUF1027)
GEMNEGCL_00140 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GEMNEGCL_00141 9.89e-74 - - - - - - - -
GEMNEGCL_00142 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GEMNEGCL_00143 1.23e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GEMNEGCL_00144 1.6e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GEMNEGCL_00145 4.64e-63 - - - S - - - Domain of unknown function (DUF4811)
GEMNEGCL_00146 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
GEMNEGCL_00147 8.94e-100 - - - K - - - MerR HTH family regulatory protein
GEMNEGCL_00148 1.43e-178 - - - S - - - Cysteine-rich secretory protein family
GEMNEGCL_00149 0.0 ycaM - - E - - - amino acid
GEMNEGCL_00150 0.0 - - - - - - - -
GEMNEGCL_00152 9.53e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
GEMNEGCL_00153 2.86e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GEMNEGCL_00154 2.86e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GEMNEGCL_00155 5.46e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GEMNEGCL_00156 1.18e-253 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GEMNEGCL_00157 3.07e-124 - - - - - - - -
GEMNEGCL_00158 2.81e-200 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
GEMNEGCL_00159 1.64e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GEMNEGCL_00160 1.1e-232 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
GEMNEGCL_00161 4.82e-113 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
GEMNEGCL_00162 1.51e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GEMNEGCL_00163 2.84e-208 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
GEMNEGCL_00164 1.25e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GEMNEGCL_00165 8.77e-173 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEMNEGCL_00166 3.69e-170 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEMNEGCL_00167 2.33e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEMNEGCL_00168 2.13e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GEMNEGCL_00169 2.76e-221 ybbR - - S - - - YbbR-like protein
GEMNEGCL_00170 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEMNEGCL_00171 8.04e-190 - - - S - - - hydrolase
GEMNEGCL_00172 3.23e-98 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
GEMNEGCL_00173 2.85e-153 - - - - - - - -
GEMNEGCL_00174 3.07e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEMNEGCL_00175 1.25e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GEMNEGCL_00176 2.78e-14 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
GEMNEGCL_00177 1.19e-155 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
GEMNEGCL_00178 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GEMNEGCL_00179 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GEMNEGCL_00180 5.92e-235 ybcH - - D ko:K06889 - ko00000 Alpha beta
GEMNEGCL_00181 0.0 - - - E - - - Amino acid permease
GEMNEGCL_00183 4.8e-38 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GEMNEGCL_00184 7.83e-140 ylbE - - GM - - - NAD(P)H-binding
GEMNEGCL_00185 3.31e-120 - - - S - - - VanZ like family
GEMNEGCL_00186 5.65e-171 yebC - - K - - - Transcriptional regulatory protein
GEMNEGCL_00187 5.04e-231 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
GEMNEGCL_00188 1.72e-222 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GEMNEGCL_00189 7.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
GEMNEGCL_00190 9.96e-92 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
GEMNEGCL_00191 1.96e-54 - - - - - - - -
GEMNEGCL_00192 1.31e-98 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
GEMNEGCL_00193 3.69e-30 - - - - - - - -
GEMNEGCL_00194 4.37e-241 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
GEMNEGCL_00195 1.07e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GEMNEGCL_00197 2.26e-188 int3 - - L - - - Belongs to the 'phage' integrase family
GEMNEGCL_00199 1.11e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
GEMNEGCL_00200 3.11e-30 - - - K - - - Helix-turn-helix XRE-family like proteins
GEMNEGCL_00201 3.68e-33 - - - K - - - Helix-turn-helix domain
GEMNEGCL_00202 2.72e-35 - - - S - - - Domain of unknown function (DUF771)
GEMNEGCL_00211 5.69e-06 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GEMNEGCL_00217 2.94e-166 - - - M - - - LPXTG-motif cell wall anchor domain protein
GEMNEGCL_00218 4.55e-221 - - - M - - - LPXTG-motif cell wall anchor domain protein
GEMNEGCL_00219 5e-53 - - - M - - - LPXTG-motif cell wall anchor domain protein
GEMNEGCL_00220 3.88e-52 - - - M - - - LPXTG-motif cell wall anchor domain protein
GEMNEGCL_00221 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GEMNEGCL_00222 2.48e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GEMNEGCL_00223 3.2e-143 - - - S - - - SNARE associated Golgi protein
GEMNEGCL_00224 3.56e-102 - - - - - - - -
GEMNEGCL_00225 0.0 - - - L - - - Plasmid pRiA4b ORF-3-like protein
GEMNEGCL_00226 2.32e-313 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GEMNEGCL_00227 8.75e-197 - - - - - - - -
GEMNEGCL_00228 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
GEMNEGCL_00229 8.28e-176 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GEMNEGCL_00230 4.71e-239 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
GEMNEGCL_00231 3.42e-30 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
GEMNEGCL_00232 1.23e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GEMNEGCL_00233 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GEMNEGCL_00234 6.69e-239 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GEMNEGCL_00237 1.84e-263 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
GEMNEGCL_00238 5.12e-242 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
GEMNEGCL_00239 6.45e-291 - - - E - - - amino acid
GEMNEGCL_00240 6.65e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
GEMNEGCL_00241 4.31e-204 - - - L ko:K07497 - ko00000 hmm pf00665
GEMNEGCL_00242 2.43e-108 - - - L - - - Helix-turn-helix domain
GEMNEGCL_00243 2.15e-194 - - - L - - - Phage integrase, N-terminal SAM-like domain
GEMNEGCL_00244 7.7e-126 - - - L - - - Helix-turn-helix domain
GEMNEGCL_00245 3.21e-175 - - - L ko:K07497 - ko00000 hmm pf00665
GEMNEGCL_00247 3.38e-91 - - - M - - - Glycosyltransferase like family 2
GEMNEGCL_00248 2.76e-188 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GEMNEGCL_00249 2.39e-85 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GEMNEGCL_00250 3.05e-53 - 2.7.1.200 - GT ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GEMNEGCL_00251 3.94e-254 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
GEMNEGCL_00252 1.38e-46 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GEMNEGCL_00253 8.46e-98 - - - S - - - Uncharacterised protein family UPF0047
GEMNEGCL_00254 1.55e-82 - - - M - - - SIS domain
GEMNEGCL_00255 3.53e-63 hxlB 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
GEMNEGCL_00256 5.28e-215 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
GEMNEGCL_00257 2.16e-163 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GEMNEGCL_00258 5.7e-282 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GEMNEGCL_00259 1.05e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_00260 1.61e-101 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
GEMNEGCL_00261 1.2e-41 - - - - - - - -
GEMNEGCL_00262 1.09e-196 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GEMNEGCL_00263 1.64e-95 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
GEMNEGCL_00264 0.0 - - - - - - - -
GEMNEGCL_00265 9.67e-33 - - - S - - - Domain of unknown function DUF1829
GEMNEGCL_00267 4.53e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
GEMNEGCL_00268 0.0 yhaN - - L - - - AAA domain
GEMNEGCL_00269 6.56e-293 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
GEMNEGCL_00270 8.43e-73 yheA - - S - - - Belongs to the UPF0342 family
GEMNEGCL_00271 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GEMNEGCL_00272 2.09e-208 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GEMNEGCL_00273 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GEMNEGCL_00274 1.49e-13 - - - G - - - Phosphoglycerate mutase family
GEMNEGCL_00275 1.91e-102 - - - G - - - Phosphoglycerate mutase family
GEMNEGCL_00276 9.44e-183 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GEMNEGCL_00277 0.0 XK27_08315 - - M - - - Sulfatase
GEMNEGCL_00278 8.24e-85 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GEMNEGCL_00279 9.78e-257 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GEMNEGCL_00280 5.18e-128 - - - G - - - Aldose 1-epimerase
GEMNEGCL_00281 4.51e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GEMNEGCL_00282 1.72e-149 - - - - - - - -
GEMNEGCL_00283 1.98e-168 - - - - - - - -
GEMNEGCL_00284 1.68e-207 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
GEMNEGCL_00285 2.47e-138 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GEMNEGCL_00286 7.07e-141 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
GEMNEGCL_00287 1.64e-222 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
GEMNEGCL_00288 7.32e-232 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
GEMNEGCL_00289 2.09e-286 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GEMNEGCL_00291 4.65e-278 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GEMNEGCL_00293 1.97e-315 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GEMNEGCL_00294 5.96e-283 yfmL - - L - - - DEAD DEAH box helicase
GEMNEGCL_00295 6.12e-167 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GEMNEGCL_00296 7.42e-156 - - - L - - - PFAM transposase IS116 IS110 IS902
GEMNEGCL_00297 1.39e-205 - - - L - - - DDE superfamily endonuclease
GEMNEGCL_00298 1.97e-198 - - - L - - - DDE superfamily endonuclease
GEMNEGCL_00299 9.82e-80 - - - F - - - NUDIX domain
GEMNEGCL_00300 1.83e-103 - - - S - - - AAA domain
GEMNEGCL_00301 1.5e-150 - - - S - - - F420-0:Gamma-glutamyl ligase
GEMNEGCL_00302 1.59e-85 yxaM - - EGP - - - Major facilitator Superfamily
GEMNEGCL_00303 3.24e-112 yxaM - - EGP - - - Major facilitator Superfamily
GEMNEGCL_00304 2.16e-73 - - - M - - - Rib/alpha-like repeat
GEMNEGCL_00305 9.48e-31 - - - - - - - -
GEMNEGCL_00306 4.01e-84 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
GEMNEGCL_00307 5.51e-46 - - - S - - - Transposase C of IS166 homeodomain
GEMNEGCL_00308 1.28e-311 - - - L ko:K07484 - ko00000 Transposase IS66 family
GEMNEGCL_00310 4.51e-69 - - - - - - - -
GEMNEGCL_00311 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GEMNEGCL_00312 2.13e-66 - - - - - - - -
GEMNEGCL_00313 2.32e-234 - - - S - - - AAA domain
GEMNEGCL_00314 9.82e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GEMNEGCL_00315 2.42e-33 - - - - - - - -
GEMNEGCL_00316 8.43e-206 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
GEMNEGCL_00317 3.16e-160 - - - G - - - Belongs to the phosphoglycerate mutase family
GEMNEGCL_00318 2.02e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
GEMNEGCL_00319 1.1e-152 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GEMNEGCL_00320 4.57e-135 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
GEMNEGCL_00321 7.12e-65 - - - S - - - Protein of unknown function (DUF3021)
GEMNEGCL_00322 4.4e-86 - - - K - - - LytTr DNA-binding domain
GEMNEGCL_00324 1.77e-298 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GEMNEGCL_00325 1.45e-36 - - - S - - - Peptidase propeptide and YPEB domain
GEMNEGCL_00326 1.73e-79 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
GEMNEGCL_00327 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GEMNEGCL_00328 9.18e-202 - - - C - - - Domain of unknown function (DUF4931)
GEMNEGCL_00329 1.58e-154 - - - - - - - -
GEMNEGCL_00330 1.45e-183 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
GEMNEGCL_00331 1.39e-180 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
GEMNEGCL_00333 1.93e-143 - - - G - - - phosphoglycerate mutase
GEMNEGCL_00334 2.41e-118 - - - K - - - Bacterial regulatory proteins, tetR family
GEMNEGCL_00335 1.05e-233 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GEMNEGCL_00336 2.12e-132 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_00337 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GEMNEGCL_00338 3.84e-179 - - - L - - - An automated process has identified a potential problem with this gene model
GEMNEGCL_00339 3.77e-122 - - - S - - - SNARE associated Golgi protein
GEMNEGCL_00340 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GEMNEGCL_00341 7.96e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GEMNEGCL_00342 1.91e-195 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GEMNEGCL_00343 1.7e-147 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
GEMNEGCL_00344 1.71e-143 - - - S - - - CYTH
GEMNEGCL_00345 5.74e-148 yjbH - - Q - - - Thioredoxin
GEMNEGCL_00346 3.83e-17 coiA - - S ko:K06198 - ko00000 Competence protein
GEMNEGCL_00347 7.37e-158 coiA - - S ko:K06198 - ko00000 Competence protein
GEMNEGCL_00348 1.5e-178 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GEMNEGCL_00349 6.28e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GEMNEGCL_00350 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GEMNEGCL_00351 1.29e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
GEMNEGCL_00352 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
GEMNEGCL_00353 8.42e-60 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
GEMNEGCL_00354 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GEMNEGCL_00355 1.51e-182 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
GEMNEGCL_00356 3.85e-98 - - - - - - - -
GEMNEGCL_00357 1.43e-110 - - - - - - - -
GEMNEGCL_00358 1.38e-185 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
GEMNEGCL_00359 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GEMNEGCL_00360 1.17e-151 ybcH - - D ko:K06889 - ko00000 Alpha beta
GEMNEGCL_00361 1.52e-34 ybcH - - D ko:K06889 - ko00000 Alpha beta
GEMNEGCL_00362 2.6e-59 - - - - - - - -
GEMNEGCL_00363 7.15e-277 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
GEMNEGCL_00364 3.65e-273 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
GEMNEGCL_00365 8.62e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GEMNEGCL_00366 1.6e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GEMNEGCL_00367 1.4e-208 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GEMNEGCL_00368 2.45e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
GEMNEGCL_00369 5.14e-105 ykuP - - C ko:K03839 - ko00000 Flavodoxin
GEMNEGCL_00370 3.7e-113 gtcA1 - - S - - - Teichoic acid glycosylation protein
GEMNEGCL_00371 3.37e-15 - - - S - - - SLAP domain
GEMNEGCL_00372 3.69e-20 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
GEMNEGCL_00374 8.51e-10 - - - M - - - oxidoreductase activity
GEMNEGCL_00379 2.46e-162 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
GEMNEGCL_00383 9.21e-194 - - - S - - - COG0433 Predicted ATPase
GEMNEGCL_00384 8.52e-25 lysM - - M - - - LysM domain
GEMNEGCL_00393 6.11e-33 - - - L - - - four-way junction helicase activity
GEMNEGCL_00394 3.87e-23 - - - L - - - Psort location Cytoplasmic, score
GEMNEGCL_00395 1.11e-143 - - - S - - - Fic/DOC family
GEMNEGCL_00396 1.42e-54 - - - E - - - Pfam:DUF955
GEMNEGCL_00397 1.19e-31 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
GEMNEGCL_00398 1.33e-22 - - - S - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
GEMNEGCL_00399 3.24e-290 - - - L - - - COG3547 Transposase and inactivated derivatives
GEMNEGCL_00401 1.31e-231 - - - S ko:K07133 - ko00000 cog cog1373
GEMNEGCL_00404 1.91e-233 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GEMNEGCL_00405 2.85e-27 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00406 2.85e-27 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00407 3.74e-125 - - - - - - - -
GEMNEGCL_00408 1.94e-96 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
GEMNEGCL_00409 1.82e-05 - - - - - - - -
GEMNEGCL_00410 1.38e-225 - - - M - - - Rib/alpha-like repeat
GEMNEGCL_00411 4.21e-148 - - - M - - - Rib/alpha-like repeat
GEMNEGCL_00412 1.89e-129 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GEMNEGCL_00414 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GEMNEGCL_00415 1.1e-54 - - - K - - - Helix-turn-helix
GEMNEGCL_00416 9.63e-136 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GEMNEGCL_00417 8.34e-294 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
GEMNEGCL_00418 2.07e-196 msmR - - K - - - AraC-like ligand binding domain
GEMNEGCL_00419 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GEMNEGCL_00420 1.69e-61 - - - F - - - AAA domain
GEMNEGCL_00421 4.61e-104 - - - K - - - acetyltransferase
GEMNEGCL_00422 6.58e-311 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GEMNEGCL_00423 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GEMNEGCL_00424 1.72e-90 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GEMNEGCL_00425 1.44e-88 - - - S - - - Domain of unknown function (DUF1934)
GEMNEGCL_00426 4.73e-32 - - - S - - - Domain of unknown function (DUF4417)
GEMNEGCL_00427 2.72e-05 - - - M ko:K11021 - ko00000,ko02042 COG3209 Rhs family protein
GEMNEGCL_00429 8.25e-16 - - - S - - - Protein conserved in bacteria
GEMNEGCL_00430 4.26e-27 - - - E - - - Pfam:DUF955
GEMNEGCL_00431 6.84e-70 - - - - - - - -
GEMNEGCL_00432 7.22e-76 - - - - - - - -
GEMNEGCL_00433 4.02e-11 - - - - - - - -
GEMNEGCL_00434 1.29e-295 - - - E ko:K03294 - ko00000 amino acid
GEMNEGCL_00435 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GEMNEGCL_00436 5.83e-67 - - - L - - - PFAM transposase, IS4 family protein
GEMNEGCL_00437 7.06e-114 - - - L - - - PFAM transposase, IS4 family protein
GEMNEGCL_00438 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GEMNEGCL_00439 8.59e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GEMNEGCL_00440 0.0 yhdP - - S - - - Transporter associated domain
GEMNEGCL_00441 2.14e-154 - - - C - - - nitroreductase
GEMNEGCL_00442 1.76e-52 - - - - - - - -
GEMNEGCL_00443 1.96e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GEMNEGCL_00444 1.52e-103 - - - - - - - -
GEMNEGCL_00445 6.89e-190 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GEMNEGCL_00446 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
GEMNEGCL_00447 7.44e-189 - - - S - - - hydrolase
GEMNEGCL_00448 1.85e-205 - - - S - - - Phospholipase, patatin family
GEMNEGCL_00449 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GEMNEGCL_00450 6.3e-174 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
GEMNEGCL_00451 2.9e-79 - - - S - - - Enterocin A Immunity
GEMNEGCL_00452 7.49e-197 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GEMNEGCL_00453 6.63e-174 gntR - - K - - - UbiC transcription regulator-associated domain protein
GEMNEGCL_00454 1.01e-222 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
GEMNEGCL_00455 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
GEMNEGCL_00456 6.36e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GEMNEGCL_00457 7.3e-216 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEMNEGCL_00458 1.04e-208 - - - C - - - Domain of unknown function (DUF4931)
GEMNEGCL_00459 3.81e-22 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GEMNEGCL_00460 7.24e-270 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GEMNEGCL_00461 4.77e-294 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GEMNEGCL_00462 2.18e-112 - - - GKT - - - domain protein
GEMNEGCL_00463 0.0 - 3.2.1.170, 3.2.1.24 GH38 G ko:K01191,ko:K15524 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Glycosyl hydrolases family 38 N-terminal domain
GEMNEGCL_00464 4.34e-198 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 system, fructose-specific IIC component
GEMNEGCL_00465 5.84e-50 - - - G - - - Psort location Cytoplasmic, score 9.98
GEMNEGCL_00466 2.4e-54 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GEMNEGCL_00467 2.77e-25 - - - - - - - -
GEMNEGCL_00468 1.21e-40 - - - - - - - -
GEMNEGCL_00469 1.05e-54 - - - S - - - Protein of unknown function (DUF2922)
GEMNEGCL_00470 7.39e-165 - - - S - - - SLAP domain
GEMNEGCL_00472 2.85e-54 - - - - - - - -
GEMNEGCL_00473 3.6e-101 - - - K - - - DNA-templated transcription, initiation
GEMNEGCL_00475 4.56e-191 - - - S - - - PD-(D/E)XK nuclease family transposase
GEMNEGCL_00476 6.87e-27 - - - S - - - PD-(D/E)XK nuclease family transposase
GEMNEGCL_00477 1.2e-89 - - - S - - - SLAP domain
GEMNEGCL_00481 3.34e-63 sagD - - S - - - YcaO cyclodehydratase, ATP-ad Mg2+-binding
GEMNEGCL_00482 2.18e-79 sagD - - S - - - YcaO cyclodehydratase, ATP-ad Mg2+-binding
GEMNEGCL_00484 9.29e-86 sagB - - C - - - Nitroreductase family
GEMNEGCL_00486 8.25e-65 - - - V ko:K01990,ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
GEMNEGCL_00487 9.75e-80 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GEMNEGCL_00489 3.5e-280 - - - L - - - Belongs to the 'phage' integrase family
GEMNEGCL_00490 4.04e-36 - - - - - - - -
GEMNEGCL_00491 1.33e-72 - - - - - - - -
GEMNEGCL_00492 1.74e-185 - - - S - - - Replication initiation factor
GEMNEGCL_00493 2.67e-180 - - - D - - - Ftsk spoiiie family protein
GEMNEGCL_00494 6.59e-115 - - - - - - - -
GEMNEGCL_00495 4.95e-98 - - - - - - - -
GEMNEGCL_00496 6.48e-167 - - - K - - - Helix-turn-helix XRE-family like proteins
GEMNEGCL_00498 3.92e-153 - - - S ko:K07507 - ko00000,ko02000 MgtC family
GEMNEGCL_00499 1.37e-287 - - - I - - - Protein of unknown function (DUF2974)
GEMNEGCL_00500 1.5e-90 - - - - - - - -
GEMNEGCL_00501 4.36e-142 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
GEMNEGCL_00502 3.35e-269 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GEMNEGCL_00503 1.34e-34 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00504 3.76e-18 - - - K - - - Acetyltransferase (GNAT) domain
GEMNEGCL_00505 7.51e-16 - - - L - - - Transposase
GEMNEGCL_00506 1.01e-22 - - - L - - - Transposase
GEMNEGCL_00507 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GEMNEGCL_00508 5.85e-86 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
GEMNEGCL_00509 1.52e-157 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GEMNEGCL_00510 1.78e-163 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
GEMNEGCL_00511 2.85e-115 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
GEMNEGCL_00512 4.82e-42 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GEMNEGCL_00513 6.58e-293 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
GEMNEGCL_00514 4.93e-80 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GEMNEGCL_00515 6.33e-221 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
GEMNEGCL_00516 1.29e-190 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GEMNEGCL_00517 1.91e-168 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GEMNEGCL_00518 6.34e-180 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GEMNEGCL_00519 1.78e-212 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
GEMNEGCL_00521 3.92e-110 usp5 - - T - - - universal stress protein
GEMNEGCL_00522 3.56e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GEMNEGCL_00523 7.6e-113 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GEMNEGCL_00524 1.14e-115 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
GEMNEGCL_00526 1.47e-13 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GEMNEGCL_00527 1.11e-09 - - - T ko:K07172 - ko00000,ko02048 SpoVT / AbrB like domain
GEMNEGCL_00529 5.55e-22 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
GEMNEGCL_00530 4.83e-125 - - - D ko:K03496 - ko00000,ko03036,ko04812 VirC1 protein
GEMNEGCL_00532 3.54e-53 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
GEMNEGCL_00533 6.8e-48 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
GEMNEGCL_00534 4.82e-102 - - - V - - - Type I restriction modification DNA specificity domain
GEMNEGCL_00535 2.37e-214 - - - V - - - N-6 DNA Methylase
GEMNEGCL_00536 2.61e-195 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GEMNEGCL_00537 1.3e-31 - - - - - - - -
GEMNEGCL_00538 1.34e-175 - - - K - - - Helix-turn-helix XRE-family like proteins
GEMNEGCL_00540 1.49e-151 - - - V - - - Abi-like protein
GEMNEGCL_00542 5.38e-125 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
GEMNEGCL_00543 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_00544 3.51e-187 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
GEMNEGCL_00545 1.46e-31 - - - - - - - -
GEMNEGCL_00546 7.19e-93 ytwI - - S - - - Protein of unknown function (DUF441)
GEMNEGCL_00547 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
GEMNEGCL_00548 3.46e-212 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
GEMNEGCL_00549 1.6e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
GEMNEGCL_00550 5.17e-249 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GEMNEGCL_00551 4.89e-196 - - - I - - - Alpha/beta hydrolase family
GEMNEGCL_00552 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GEMNEGCL_00553 5.26e-171 - - - H - - - Aldolase/RraA
GEMNEGCL_00554 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GEMNEGCL_00555 1.66e-217 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GEMNEGCL_00556 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GEMNEGCL_00557 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GEMNEGCL_00558 2.34e-122 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEMNEGCL_00559 5.74e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GEMNEGCL_00560 4.37e-205 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GEMNEGCL_00561 1.33e-225 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
GEMNEGCL_00562 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
GEMNEGCL_00563 5.55e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GEMNEGCL_00564 3.53e-228 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GEMNEGCL_00565 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
GEMNEGCL_00566 8.44e-306 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GEMNEGCL_00567 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
GEMNEGCL_00568 6.04e-49 - - - - - - - -
GEMNEGCL_00570 1.46e-161 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GEMNEGCL_00571 7.94e-114 - - - K - - - GNAT family
GEMNEGCL_00572 3.7e-258 XK27_00915 - - C - - - Luciferase-like monooxygenase
GEMNEGCL_00573 3.8e-213 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
GEMNEGCL_00574 7.1e-136 ybbB - - S - - - Protein of unknown function (DUF1211)
GEMNEGCL_00575 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GEMNEGCL_00576 3.46e-32 - - - S - - - Alpha beta hydrolase
GEMNEGCL_00577 1.47e-303 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GEMNEGCL_00578 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
GEMNEGCL_00579 2.51e-52 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
GEMNEGCL_00580 7.63e-43 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
GEMNEGCL_00581 3.04e-45 - - - L - - - Transposase and inactivated derivatives, IS30 family
GEMNEGCL_00582 2.16e-193 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
GEMNEGCL_00583 6.64e-185 - - - F - - - Phosphorylase superfamily
GEMNEGCL_00584 1.05e-176 - - - F - - - Phosphorylase superfamily
GEMNEGCL_00585 4.89e-101 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
GEMNEGCL_00586 8.74e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GEMNEGCL_00587 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
GEMNEGCL_00588 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GEMNEGCL_00589 8.98e-214 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GEMNEGCL_00590 2.44e-64 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GEMNEGCL_00591 1.42e-247 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GEMNEGCL_00592 4.59e-124 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
GEMNEGCL_00593 1.83e-171 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
GEMNEGCL_00594 8.72e-111 - - - S - - - ECF transporter, substrate-specific component
GEMNEGCL_00595 3e-167 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
GEMNEGCL_00596 8.75e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GEMNEGCL_00597 1.4e-80 yabA - - L - - - Involved in initiation control of chromosome replication
GEMNEGCL_00598 3.99e-197 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GEMNEGCL_00599 7.55e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
GEMNEGCL_00600 1.29e-143 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GEMNEGCL_00601 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
GEMNEGCL_00602 3.08e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GEMNEGCL_00603 1.55e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GEMNEGCL_00604 1.15e-47 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
GEMNEGCL_00605 1.12e-136 - - - M - - - family 8
GEMNEGCL_00606 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GEMNEGCL_00607 1.44e-108 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GEMNEGCL_00609 9.69e-25 - - - - - - - -
GEMNEGCL_00610 1.42e-102 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
GEMNEGCL_00611 1.68e-274 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
GEMNEGCL_00612 1.94e-91 - - - S - - - Iron-sulphur cluster biosynthesis
GEMNEGCL_00613 1.25e-244 ysdE - - P - - - Citrate transporter
GEMNEGCL_00614 6.78e-124 lemA - - S ko:K03744 - ko00000 LemA family
GEMNEGCL_00615 1.64e-207 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GEMNEGCL_00616 1.05e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
GEMNEGCL_00617 1.88e-63 - - - L - - - PFAM transposase, IS4 family protein
GEMNEGCL_00618 6.89e-43 - - - L - - - Transposase DDE domain
GEMNEGCL_00619 0.0 - - - L - - - Transposase
GEMNEGCL_00620 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GEMNEGCL_00621 1.82e-97 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
GEMNEGCL_00622 1e-247 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GEMNEGCL_00623 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GEMNEGCL_00624 6.08e-153 phoB - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
GEMNEGCL_00625 3.12e-135 - - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GEMNEGCL_00626 1.68e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GEMNEGCL_00627 4.1e-193 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GEMNEGCL_00628 3.26e-200 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GEMNEGCL_00629 6.7e-187 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GEMNEGCL_00630 5.68e-34 - - - L - - - Phage integrase, N-terminal SAM-like domain
GEMNEGCL_00631 7.06e-102 yveB - - I - - - PAP2 superfamily
GEMNEGCL_00633 1.38e-131 - - - - - - - -
GEMNEGCL_00634 1.69e-49 - - - L - - - PFAM transposase, IS4 family protein
GEMNEGCL_00635 2.2e-97 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_00636 6.1e-186 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_00637 2.26e-31 - - - S - - - Transglycosylase associated protein
GEMNEGCL_00638 6.33e-17 - - - S - - - CsbD-like
GEMNEGCL_00639 4.76e-213 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
GEMNEGCL_00640 6.11e-171 - - - V - - - ABC transporter transmembrane region
GEMNEGCL_00641 2.36e-217 degV1 - - S - - - DegV family
GEMNEGCL_00642 5.56e-217 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
GEMNEGCL_00643 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GEMNEGCL_00644 3.87e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GEMNEGCL_00645 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GEMNEGCL_00646 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GEMNEGCL_00647 4.83e-104 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GEMNEGCL_00648 2.74e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GEMNEGCL_00649 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GEMNEGCL_00650 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GEMNEGCL_00651 5.14e-268 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GEMNEGCL_00652 1.13e-48 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
GEMNEGCL_00653 7.25e-309 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
GEMNEGCL_00654 4.87e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
GEMNEGCL_00655 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GEMNEGCL_00656 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GEMNEGCL_00657 1.76e-165 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GEMNEGCL_00658 1.38e-226 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GEMNEGCL_00659 4e-204 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
GEMNEGCL_00660 1.74e-293 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GEMNEGCL_00661 3.16e-52 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GEMNEGCL_00662 4.91e-111 - - - S - - - PD-(D/E)XK nuclease family transposase
GEMNEGCL_00663 5.79e-217 - - - K - - - LysR substrate binding domain
GEMNEGCL_00664 4.86e-157 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
GEMNEGCL_00665 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GEMNEGCL_00666 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GEMNEGCL_00667 1.47e-66 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
GEMNEGCL_00669 2.71e-297 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GEMNEGCL_00670 1.23e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GEMNEGCL_00671 5.86e-131 - - - M - - - ErfK YbiS YcfS YnhG
GEMNEGCL_00672 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GEMNEGCL_00673 7.33e-218 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
GEMNEGCL_00674 1.29e-115 - - - EGP - - - Major Facilitator
GEMNEGCL_00675 3.73e-300 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GEMNEGCL_00676 7.14e-91 - - - EGP - - - Major Facilitator
GEMNEGCL_00677 2.58e-45 - - - - - - - -
GEMNEGCL_00678 3.62e-272 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
GEMNEGCL_00679 1.18e-95 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
GEMNEGCL_00681 5.89e-316 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
GEMNEGCL_00682 1.22e-195 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEMNEGCL_00683 4.48e-174 potA11 3.6.3.30 - P ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GEMNEGCL_00684 7.05e-146 potC3 - - E ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GEMNEGCL_00685 5.29e-164 - - - S - - - Alpha/beta hydrolase family
GEMNEGCL_00686 2.62e-199 epsV - - S - - - glycosyl transferase family 2
GEMNEGCL_00687 9.18e-187 - - - S - - - Protein of unknown function (DUF1002)
GEMNEGCL_00688 5.07e-190 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GEMNEGCL_00689 1.24e-232 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GEMNEGCL_00690 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEMNEGCL_00691 1.32e-57 - - - - - - - -
GEMNEGCL_00692 6.07e-223 ydhF - - S - - - Aldo keto reductase
GEMNEGCL_00693 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
GEMNEGCL_00694 4.37e-266 pepA - - E - - - M42 glutamyl aminopeptidase
GEMNEGCL_00695 1.14e-55 - - - - - - - -
GEMNEGCL_00696 2.2e-171 - - - - - - - -
GEMNEGCL_00697 1.38e-275 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
GEMNEGCL_00698 0.0 qacA - - EGP - - - Major Facilitator
GEMNEGCL_00699 1.51e-117 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GEMNEGCL_00700 1.66e-303 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
GEMNEGCL_00701 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
GEMNEGCL_00702 1.05e-45 - - - - - - - -
GEMNEGCL_00703 1.2e-199 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
GEMNEGCL_00704 6.13e-110 - - - K - - - Acetyltransferase (GNAT) domain
GEMNEGCL_00705 4.64e-296 - - - L - - - Transposase DDE domain
GEMNEGCL_00706 1.84e-151 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GEMNEGCL_00707 4.67e-54 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GEMNEGCL_00708 9.07e-51 - - - S - - - CRISPR-associated protein (Cas_Csn2)
GEMNEGCL_00709 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
GEMNEGCL_00710 1.66e-44 - - - K - - - Transcriptional regulator
GEMNEGCL_00711 4.54e-213 - - - EGP - - - Major Facilitator
GEMNEGCL_00712 1.34e-34 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00713 1.92e-212 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GEMNEGCL_00715 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GEMNEGCL_00716 7.01e-32 - - - K - - - Transcriptional regulator
GEMNEGCL_00718 8.66e-234 - - - M - - - Glycosyl transferase
GEMNEGCL_00719 2.59e-225 - - - G - - - Glycosyl hydrolases family 8
GEMNEGCL_00720 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
GEMNEGCL_00721 8.8e-207 - - - L - - - HNH nucleases
GEMNEGCL_00722 3.43e-192 yhaH - - S - - - Protein of unknown function (DUF805)
GEMNEGCL_00723 2.89e-173 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_00724 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEMNEGCL_00725 1.41e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GEMNEGCL_00726 7.63e-85 yeaO - - S - - - Protein of unknown function, DUF488
GEMNEGCL_00727 1.14e-164 terC - - P - - - Integral membrane protein TerC family
GEMNEGCL_00728 1.25e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
GEMNEGCL_00729 2.85e-27 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00730 1.13e-201 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
GEMNEGCL_00731 2.91e-83 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
GEMNEGCL_00732 8.64e-85 yybA - - K - - - Transcriptional regulator
GEMNEGCL_00733 8e-108 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GEMNEGCL_00734 5.59e-109 - - - S - - - Peptidase propeptide and YPEB domain
GEMNEGCL_00735 5.81e-98 ykoJ - - S - - - Peptidase propeptide and YPEB domain
GEMNEGCL_00736 2.37e-242 - - - T - - - GHKL domain
GEMNEGCL_00737 1.75e-168 - - - T - - - Transcriptional regulatory protein, C terminal
GEMNEGCL_00738 1.28e-228 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GEMNEGCL_00739 0.0 - - - V - - - ABC transporter transmembrane region
GEMNEGCL_00740 0.0 - - - S - - - Fibronectin type III domain
GEMNEGCL_00741 7.03e-307 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GEMNEGCL_00743 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GEMNEGCL_00744 1.77e-157 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GEMNEGCL_00745 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GEMNEGCL_00746 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GEMNEGCL_00747 0.0 - - - L - - - Transposase DDE domain
GEMNEGCL_00748 2.64e-266 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GEMNEGCL_00749 1.34e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEMNEGCL_00750 7.82e-240 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEMNEGCL_00751 4.79e-250 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GEMNEGCL_00752 6.54e-222 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GEMNEGCL_00753 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GEMNEGCL_00754 3.4e-93 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GEMNEGCL_00755 8.08e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GEMNEGCL_00756 1.17e-143 - - - - - - - -
GEMNEGCL_00758 7.04e-145 - - - E - - - Belongs to the SOS response-associated peptidase family
GEMNEGCL_00760 1.31e-71 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GEMNEGCL_00761 1e-210 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GEMNEGCL_00762 2.99e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GEMNEGCL_00764 1.27e-42 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
GEMNEGCL_00765 2.49e-145 - - - L - - - PFAM transposase, IS4 family protein
GEMNEGCL_00767 4.3e-175 - - - S - - - Alpha/beta hydrolase family
GEMNEGCL_00768 1.34e-34 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00771 2.85e-27 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00772 6.59e-160 - - - S - - - Protein of unknown function (DUF1275)
GEMNEGCL_00774 2.75e-43 - - - G ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
GEMNEGCL_00775 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
GEMNEGCL_00776 5.5e-64 - - - V - - - N-6 DNA Methylase
GEMNEGCL_00778 2.19e-87 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
GEMNEGCL_00779 2.78e-45 - - - - - - - -
GEMNEGCL_00781 4.97e-29 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GEMNEGCL_00783 2.62e-155 - - - L - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
GEMNEGCL_00785 5.73e-153 - - - - - - - -
GEMNEGCL_00786 5.04e-154 - - - G - - - Antibiotic biosynthesis monooxygenase
GEMNEGCL_00787 1.13e-126 - - - - - - - -
GEMNEGCL_00788 6.93e-140 - - - K - - - LysR substrate binding domain
GEMNEGCL_00789 4.04e-29 - - - - - - - -
GEMNEGCL_00790 1.07e-287 - - - S - - - Sterol carrier protein domain
GEMNEGCL_00791 1.76e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GEMNEGCL_00792 2.01e-135 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
GEMNEGCL_00793 5.39e-84 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GEMNEGCL_00794 2.06e-298 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
GEMNEGCL_00795 6.12e-177 lysR5 - - K - - - LysR substrate binding domain
GEMNEGCL_00796 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
GEMNEGCL_00797 4.97e-64 - - - S - - - Metal binding domain of Ada
GEMNEGCL_00798 4.78e-261 - - - S - - - Domain of unknown function (DUF389)
GEMNEGCL_00799 1.08e-223 - 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Domain of unknown function (DUF4111)
GEMNEGCL_00800 0.000386 - - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Psort location Cytoplasmic, score 9.98
GEMNEGCL_00803 4.82e-144 - - - K - - - Helix-turn-helix XRE-family like proteins
GEMNEGCL_00804 2.85e-27 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00805 5.01e-55 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GEMNEGCL_00807 4.39e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GEMNEGCL_00808 4.95e-164 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
GEMNEGCL_00809 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
GEMNEGCL_00810 2.97e-163 - - - S - - - PAS domain
GEMNEGCL_00812 4.83e-114 - - - S - - - PFAM Archaeal ATPase
GEMNEGCL_00813 2.92e-115 - - - S - - - PFAM Archaeal ATPase
GEMNEGCL_00814 7.02e-36 - - - - - - - -
GEMNEGCL_00815 2.34e-105 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
GEMNEGCL_00816 2.34e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GEMNEGCL_00817 5.37e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GEMNEGCL_00818 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GEMNEGCL_00819 1.18e-66 yrzB - - S - - - Belongs to the UPF0473 family
GEMNEGCL_00820 9.37e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GEMNEGCL_00821 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
GEMNEGCL_00822 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GEMNEGCL_00823 1.32e-305 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GEMNEGCL_00824 3.16e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
GEMNEGCL_00825 4.29e-275 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GEMNEGCL_00826 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GEMNEGCL_00827 7.58e-69 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GEMNEGCL_00828 1.39e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GEMNEGCL_00829 3.89e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GEMNEGCL_00830 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GEMNEGCL_00831 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GEMNEGCL_00832 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GEMNEGCL_00833 1.06e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GEMNEGCL_00834 2.79e-102 - - - - - - - -
GEMNEGCL_00835 2.14e-231 - - - M - - - CHAP domain
GEMNEGCL_00836 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GEMNEGCL_00837 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
GEMNEGCL_00838 2.14e-234 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GEMNEGCL_00839 3.47e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00840 3.85e-180 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
GEMNEGCL_00841 7.8e-10 - - - S - - - Protein of unknown function (DUF3290)
GEMNEGCL_00842 3.43e-187 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
GEMNEGCL_00843 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GEMNEGCL_00845 2.85e-27 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00846 1.24e-169 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
GEMNEGCL_00848 1.68e-52 - - - S - - - Transglycosylase associated protein
GEMNEGCL_00849 7.05e-100 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
GEMNEGCL_00850 1.23e-119 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GEMNEGCL_00851 3.41e-85 - - - I - - - Acyl-transferase
GEMNEGCL_00852 1.24e-78 arbx - - M - - - Glycosyl transferase family 8
GEMNEGCL_00853 2.97e-110 - - - - - - - -
GEMNEGCL_00854 3.94e-157 - - - V - - - HNH endonuclease
GEMNEGCL_00856 1.15e-64 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GEMNEGCL_00857 6.8e-50 - - - S - - - Cytochrome B5
GEMNEGCL_00858 1.12e-214 arbZ - - I - - - Phosphate acyltransferases
GEMNEGCL_00859 3.04e-232 - - - M - - - Glycosyl transferase family 8
GEMNEGCL_00860 2.04e-183 - - - M - - - Glycosyl transferase family 8
GEMNEGCL_00861 2e-16 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GEMNEGCL_00862 4.44e-16 - - - S - - - peptidoglycan catabolic process
GEMNEGCL_00863 4.42e-30 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GEMNEGCL_00864 1.6e-33 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GEMNEGCL_00865 7.4e-44 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GEMNEGCL_00866 1.21e-119 - - - F - - - Nucleoside 2-deoxyribosyltransferase
GEMNEGCL_00867 1.01e-87 - - - S ko:K07133 - ko00000 cog cog1373
GEMNEGCL_00868 1.17e-11 ytoP 3.4.11.7 - G ko:K01261 - ko00000,ko01000,ko01002 aminopeptidase
GEMNEGCL_00869 1.98e-49 - - - - - - - -
GEMNEGCL_00870 6.33e-52 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GEMNEGCL_00871 6.12e-48 rbtT - - P ko:K13021 - ko00000,ko02000 Major Facilitator Superfamily
GEMNEGCL_00872 8.63e-61 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GEMNEGCL_00873 1.93e-100 - - - S - - - helix_turn_helix, Deoxyribose operon repressor
GEMNEGCL_00874 6.72e-177 - - - EP - - - Plasmid replication protein
GEMNEGCL_00875 4.63e-32 - - - - - - - -
GEMNEGCL_00876 1.04e-24 - - - V - - - N-6 DNA Methylase
GEMNEGCL_00877 2.96e-22 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GEMNEGCL_00905 1.72e-286 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
GEMNEGCL_00906 9.03e-257 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GEMNEGCL_00907 2.91e-217 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GEMNEGCL_00910 3.3e-42 - - - - - - - -
GEMNEGCL_00911 3.98e-97 - - - M - - - LysM domain
GEMNEGCL_00912 1.81e-31 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_00913 1.45e-116 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_00914 4.03e-75 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GEMNEGCL_00915 1.91e-97 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GEMNEGCL_00916 6.82e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GEMNEGCL_00917 4.24e-178 - - - S - - - haloacid dehalogenase-like hydrolase
GEMNEGCL_00918 6.64e-94 - - - - - - - -
GEMNEGCL_00919 1.06e-159 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
GEMNEGCL_00920 9.85e-154 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
GEMNEGCL_00921 1.15e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GEMNEGCL_00922 4.04e-99 - - - S - - - Aldo/keto reductase family
GEMNEGCL_00923 9.99e-89 - - - S - - - Aldo/keto reductase family
GEMNEGCL_00924 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GEMNEGCL_00925 8.8e-262 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GEMNEGCL_00926 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
GEMNEGCL_00927 4.57e-232 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
GEMNEGCL_00928 9.76e-256 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
GEMNEGCL_00929 5.9e-130 - - - S - - - ECF transporter, substrate-specific component
GEMNEGCL_00930 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GEMNEGCL_00931 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_00932 5.26e-244 - - - S - - - DUF218 domain
GEMNEGCL_00933 1.2e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GEMNEGCL_00934 2.86e-139 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
GEMNEGCL_00935 3.62e-202 - - - EGP - - - Major facilitator Superfamily
GEMNEGCL_00936 1.05e-67 - - - - - - - -
GEMNEGCL_00937 1.91e-200 mutR - - K - - - Helix-turn-helix XRE-family like proteins
GEMNEGCL_00938 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
GEMNEGCL_00939 1.68e-55 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
GEMNEGCL_00940 2.49e-63 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
GEMNEGCL_00941 5.71e-263 napA - - P - - - Sodium/hydrogen exchanger family
GEMNEGCL_00942 0.0 cadA - - P - - - P-type ATPase
GEMNEGCL_00943 3.41e-107 ykuL - - S - - - (CBS) domain
GEMNEGCL_00944 5.11e-265 - - - S - - - Membrane
GEMNEGCL_00945 1.42e-58 - - - - - - - -
GEMNEGCL_00946 1.3e-26 - - - S - - - D-Ala-teichoic acid biosynthesis protein
GEMNEGCL_00947 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GEMNEGCL_00948 2.95e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
GEMNEGCL_00949 4.98e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GEMNEGCL_00950 6.8e-316 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GEMNEGCL_00951 1.97e-227 pbpX2 - - V - - - Beta-lactamase
GEMNEGCL_00952 2.5e-172 - - - S - - - Protein of unknown function (DUF975)
GEMNEGCL_00953 1.34e-183 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GEMNEGCL_00954 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GEMNEGCL_00955 1.96e-49 - - - - - - - -
GEMNEGCL_00956 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GEMNEGCL_00957 1.68e-161 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_00958 1.26e-303 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GEMNEGCL_00959 7.86e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GEMNEGCL_00960 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
GEMNEGCL_00961 5.08e-149 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GEMNEGCL_00962 2.58e-310 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GEMNEGCL_00963 5.27e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
GEMNEGCL_00964 1.28e-174 - - - S - - - PFAM Archaeal ATPase
GEMNEGCL_00965 1.11e-59 - - - S - - - PFAM Archaeal ATPase
GEMNEGCL_00966 7.29e-26 - - - V - - - HNH endonuclease
GEMNEGCL_00967 1.62e-250 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
GEMNEGCL_00968 2.27e-191 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
GEMNEGCL_00969 1.8e-66 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
GEMNEGCL_00970 2.39e-26 - - - - - - - -
GEMNEGCL_00971 1.79e-245 - - - S - - - Bacteriocin helveticin-J
GEMNEGCL_00972 1.86e-197 - - - M - - - Peptidase family M1 domain
GEMNEGCL_00973 9.84e-108 - - - L - - - Resolvase, N-terminal
GEMNEGCL_00974 4.5e-107 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GEMNEGCL_00975 4.2e-93 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GEMNEGCL_00976 7.29e-220 - - - S - - - SLAP domain
GEMNEGCL_00977 3.31e-299 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
GEMNEGCL_00978 3.8e-315 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GEMNEGCL_00979 2.05e-248 - - - - - - - -
GEMNEGCL_00980 4.18e-155 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GEMNEGCL_00981 1.35e-71 ytpP - - CO - - - Thioredoxin
GEMNEGCL_00982 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
GEMNEGCL_00983 2.2e-79 lysM - - M - - - LysM domain
GEMNEGCL_00984 7.62e-223 - - - - - - - -
GEMNEGCL_00985 7.61e-288 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GEMNEGCL_00986 5.95e-114 ymdB - - S - - - Macro domain protein
GEMNEGCL_00992 1.45e-74 - - - K - - - Helix-turn-helix XRE-family like proteins
GEMNEGCL_00993 1.39e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEMNEGCL_00994 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GEMNEGCL_00995 5.5e-282 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GEMNEGCL_00996 7e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GEMNEGCL_00997 1.89e-149 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
GEMNEGCL_00998 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
GEMNEGCL_00999 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
GEMNEGCL_01000 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
GEMNEGCL_01001 2.91e-99 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GEMNEGCL_01002 3.15e-259 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GEMNEGCL_01003 5.23e-229 yvdE - - K - - - helix_turn _helix lactose operon repressor
GEMNEGCL_01004 3.56e-186 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GEMNEGCL_01005 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GEMNEGCL_01006 2.85e-27 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_01007 6.09e-121 - - - - - - - -
GEMNEGCL_01009 7.04e-159 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
GEMNEGCL_01010 2.07e-203 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
GEMNEGCL_01011 1.55e-201 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEMNEGCL_01012 1.49e-178 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GEMNEGCL_01013 2.22e-60 hupB2 - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GEMNEGCL_01014 2.74e-69 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
GEMNEGCL_01015 9.43e-52 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
GEMNEGCL_01016 7.04e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
GEMNEGCL_01017 0.0 - - - S - - - membrane
GEMNEGCL_01018 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GEMNEGCL_01019 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GEMNEGCL_01020 7.92e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GEMNEGCL_01021 9.32e-154 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
GEMNEGCL_01022 1e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
GEMNEGCL_01023 4.95e-89 yqhL - - P - - - Rhodanese-like protein
GEMNEGCL_01024 1.82e-214 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GEMNEGCL_01025 5.88e-286 ynbB - - P - - - aluminum resistance
GEMNEGCL_01026 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GEMNEGCL_01027 1.37e-218 - - - - - - - -
GEMNEGCL_01028 3.46e-204 - - - - - - - -
GEMNEGCL_01029 2.79e-19 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
GEMNEGCL_01030 7.81e-42 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
GEMNEGCL_01032 6.78e-47 - - - - - - - -
GEMNEGCL_01033 2.48e-197 - - - S - - - interspecies interaction between organisms
GEMNEGCL_01034 1.28e-09 - - - S - - - PFAM HicB family
GEMNEGCL_01035 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GEMNEGCL_01036 1.57e-84 - - - K - - - Helix-turn-helix domain, rpiR family
GEMNEGCL_01037 5.61e-156 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
GEMNEGCL_01038 1.03e-112 nanK - - GK - - - ROK family
GEMNEGCL_01039 3.74e-70 - - - G - - - Xylose isomerase domain protein TIM barrel
GEMNEGCL_01040 6.95e-165 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GEMNEGCL_01041 6.48e-279 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GEMNEGCL_01042 2.82e-84 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
GEMNEGCL_01043 1.48e-28 axe1 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 acetyl xylan esterase
GEMNEGCL_01044 1.19e-141 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GEMNEGCL_01045 1.1e-155 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GEMNEGCL_01046 3.07e-136 - - - S - - - Alpha/beta hydrolase family
GEMNEGCL_01047 6.81e-140 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GEMNEGCL_01048 5.34e-143 crt 4.2.1.17 - I ko:K01715 ko00650,ko01200,map00650,map01200 ko00000,ko00001,ko01000 Enoyl-CoA hydratase/isomerase
GEMNEGCL_01049 1.02e-192 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
GEMNEGCL_01050 8.45e-102 pct 2.8.3.1 - I ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 ko00000,ko00001,ko01000 Coenzyme A transferase
GEMNEGCL_01051 5.53e-203 pct 2.8.3.1 - I ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 ko00000,ko00001,ko01000 Coenzyme A transferase
GEMNEGCL_01052 5.38e-184 - - - K - - - LysR substrate binding domain
GEMNEGCL_01053 1.47e-70 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GEMNEGCL_01054 1.41e-97 - - - S - - - ECF transporter, substrate-specific component
GEMNEGCL_01056 1.69e-94 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GEMNEGCL_01057 5.56e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GEMNEGCL_01058 5.7e-291 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GEMNEGCL_01059 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GEMNEGCL_01060 1.71e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GEMNEGCL_01061 6.91e-175 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GEMNEGCL_01062 1.64e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GEMNEGCL_01063 1.66e-268 - - - S - - - SLAP domain
GEMNEGCL_01064 6.64e-154 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
GEMNEGCL_01065 6.01e-147 - - - E - - - GDSL-like Lipase/Acylhydrolase family
GEMNEGCL_01066 3.45e-144 - - - L - - - Resolvase, N-terminal
GEMNEGCL_01067 2.58e-259 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GEMNEGCL_01069 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GEMNEGCL_01070 4.16e-51 ynzC - - S - - - UPF0291 protein
GEMNEGCL_01071 1.3e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
GEMNEGCL_01072 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEMNEGCL_01073 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEMNEGCL_01074 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GEMNEGCL_01075 4.94e-292 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
GEMNEGCL_01076 1.65e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
GEMNEGCL_01077 2.03e-251 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
GEMNEGCL_01078 2.21e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GEMNEGCL_01079 1.76e-235 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GEMNEGCL_01080 5.86e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GEMNEGCL_01081 1.22e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GEMNEGCL_01082 6.38e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GEMNEGCL_01083 3.93e-181 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GEMNEGCL_01084 6.38e-254 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GEMNEGCL_01085 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GEMNEGCL_01086 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GEMNEGCL_01087 3.4e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GEMNEGCL_01088 1.19e-259 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GEMNEGCL_01089 3.75e-63 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
GEMNEGCL_01090 1.61e-64 ylxQ - - J - - - ribosomal protein
GEMNEGCL_01091 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GEMNEGCL_01092 1.67e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GEMNEGCL_01093 1.64e-198 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GEMNEGCL_01094 5.35e-223 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GEMNEGCL_01095 2.56e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GEMNEGCL_01096 3.74e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GEMNEGCL_01097 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GEMNEGCL_01098 5.88e-278 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GEMNEGCL_01099 2.57e-108 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GEMNEGCL_01100 8.08e-160 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GEMNEGCL_01101 1.25e-17 - - - - - - - -
GEMNEGCL_01102 2.77e-220 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
GEMNEGCL_01103 1.04e-41 - - - - - - - -
GEMNEGCL_01105 3.65e-90 - - - S - - - Iron-sulphur cluster biosynthesis
GEMNEGCL_01106 1.08e-145 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
GEMNEGCL_01107 4.51e-77 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
GEMNEGCL_01109 6.58e-175 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GEMNEGCL_01110 1.58e-284 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
GEMNEGCL_01111 7.82e-80 - - - - - - - -
GEMNEGCL_01112 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
GEMNEGCL_01113 4.13e-310 - - - P - - - P-loop Domain of unknown function (DUF2791)
GEMNEGCL_01114 0.0 - - - S - - - TerB-C domain
GEMNEGCL_01115 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
GEMNEGCL_01116 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
GEMNEGCL_01117 6.94e-202 - - - K - - - Helix-turn-helix XRE-family like proteins
GEMNEGCL_01118 9.05e-78 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
GEMNEGCL_01119 3.36e-42 - - - - - - - -
GEMNEGCL_01120 2.53e-100 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
GEMNEGCL_01121 5.26e-36 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
GEMNEGCL_01122 2.7e-277 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
GEMNEGCL_01123 5.75e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GEMNEGCL_01124 2.34e-147 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GEMNEGCL_01125 3.13e-249 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GEMNEGCL_01126 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
GEMNEGCL_01127 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GEMNEGCL_01128 1.56e-112 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GEMNEGCL_01129 2.7e-133 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GEMNEGCL_01130 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GEMNEGCL_01131 1.13e-308 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GEMNEGCL_01132 7.06e-111 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GEMNEGCL_01133 2.07e-203 - - - K - - - Transcriptional regulator
GEMNEGCL_01134 1.31e-81 - - - S - - - Domain of unknown function (DUF956)
GEMNEGCL_01135 3.51e-222 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
GEMNEGCL_01136 9.65e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
GEMNEGCL_01137 4.5e-235 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
GEMNEGCL_01139 2.78e-32 - - - S - - - Domain of unknown function (DUF771)
GEMNEGCL_01142 8.12e-08 - - - K - - - Tetratricopeptide repeat
GEMNEGCL_01144 2.2e-68 - - - S - - - Protein of unknown function (DUF1351)
GEMNEGCL_01145 3.7e-55 - - - S - - - ERF superfamily
GEMNEGCL_01147 3.8e-13 ansR - - K - - - Transcriptional regulator
GEMNEGCL_01149 2.02e-20 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
GEMNEGCL_01158 5.03e-88 - - - S - - - ORF6C domain
GEMNEGCL_01160 4.03e-47 - - - S - - - VRR_NUC
GEMNEGCL_01167 3.48e-27 - - - S - - - N-methyltransferase activity
GEMNEGCL_01170 1.16e-231 - - - S - - - Terminase-like family
GEMNEGCL_01171 8.21e-111 - - - S ko:K09961 - ko00000 Protein of unknown function (DUF1073)
GEMNEGCL_01172 7.62e-69 - - - S - - - Phage Mu protein F like protein
GEMNEGCL_01173 9.61e-28 - - - S - - - Lysin motif
GEMNEGCL_01174 4.2e-72 - - - S ko:K09960 - ko00000 Uncharacterized protein conserved in bacteria (DUF2213)
GEMNEGCL_01175 6.37e-25 - - - - - - - -
GEMNEGCL_01177 5.49e-36 - - - S - - - Protein of unknown function (DUF4054)
GEMNEGCL_01178 5.56e-22 - - - - - - - -
GEMNEGCL_01181 2.86e-168 - - - S - - - Protein of unknown function (DUF3383)
GEMNEGCL_01184 1.69e-236 - - - L - - - Phage tail tape measure protein TP901
GEMNEGCL_01185 3.85e-54 - - - M - - - LysM domain
GEMNEGCL_01186 9.82e-61 - - - - - - - -
GEMNEGCL_01187 2.3e-128 - - - - - - - -
GEMNEGCL_01188 4.1e-49 - - - - - - - -
GEMNEGCL_01189 1.55e-40 - - - - - - - -
GEMNEGCL_01190 8.27e-140 - - - S - - - Baseplate J-like protein
GEMNEGCL_01192 3.95e-17 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
GEMNEGCL_01195 4.17e-54 - - - - - - - -
GEMNEGCL_01196 2.12e-27 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
GEMNEGCL_01199 1.81e-26 - - - - - - - -
GEMNEGCL_01200 1.24e-38 - - - - - - - -
GEMNEGCL_01201 6.18e-220 - - - M - - - Glycosyl hydrolases family 25
GEMNEGCL_01202 5.3e-32 - - - - - - - -
GEMNEGCL_01203 7.96e-46 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GEMNEGCL_01204 2.63e-194 int3 - - L - - - Belongs to the 'phage' integrase family
GEMNEGCL_01207 3.05e-19 - - - K - - - Helix-turn-helix domain
GEMNEGCL_01208 1.15e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GEMNEGCL_01209 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GEMNEGCL_01210 7e-131 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
GEMNEGCL_01214 2.16e-220 - - - M - - - Glycosyl hydrolases family 25
GEMNEGCL_01215 2.65e-40 - - - - - - - -
GEMNEGCL_01216 1.81e-24 - - - - - - - -
GEMNEGCL_01219 6.09e-29 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
GEMNEGCL_01220 1.6e-89 - - - - - - - -
GEMNEGCL_01227 3.02e-87 - - - - - - - -
GEMNEGCL_01228 8.74e-33 - - - - - - - -
GEMNEGCL_01231 5.96e-158 - - - S - - - Baseplate J-like protein
GEMNEGCL_01232 2.75e-42 - - - - - - - -
GEMNEGCL_01233 1.68e-58 - - - - - - - -
GEMNEGCL_01234 9.61e-130 - - - - - - - -
GEMNEGCL_01235 6.91e-61 - - - - - - - -
GEMNEGCL_01236 7.54e-70 - - - M - - - LysM domain
GEMNEGCL_01237 0.0 - - - L - - - Phage tail tape measure protein TP901
GEMNEGCL_01240 3.14e-72 - - - - - - - -
GEMNEGCL_01241 6.1e-191 - - - S - - - Protein of unknown function (DUF3383)
GEMNEGCL_01242 1.6e-68 - - - - - - - -
GEMNEGCL_01243 4.42e-60 - - - - - - - -
GEMNEGCL_01244 2.18e-96 - - - - - - - -
GEMNEGCL_01246 1.11e-182 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2184)
GEMNEGCL_01247 3.08e-76 - - - - - - - -
GEMNEGCL_01248 3.82e-132 - - - S ko:K09960 - ko00000 Uncharacterized protein conserved in bacteria (DUF2213)
GEMNEGCL_01249 3.12e-35 - - - S - - - Lysin motif
GEMNEGCL_01250 3.94e-125 - - - S - - - Phage Mu protein F like protein
GEMNEGCL_01251 7.5e-177 - - - S ko:K09961 - ko00000 Protein of unknown function (DUF1073)
GEMNEGCL_01252 2.4e-291 - - - S - - - Terminase-like family
GEMNEGCL_01253 7.11e-50 - - - L ko:K07474 - ko00000 Terminase small subunit
GEMNEGCL_01255 1.04e-39 - - - S - - - Psort location Cytoplasmic, score 8.87
GEMNEGCL_01264 1.51e-10 - - - - - - - -
GEMNEGCL_01265 2.98e-52 - - - L - - - Endodeoxyribonuclease RusA
GEMNEGCL_01273 5.53e-81 - - - Q - - - DNA (cytosine-5-)-methyltransferase activity
GEMNEGCL_01279 1.89e-22 - - - L - - - Psort location Cytoplasmic, score
GEMNEGCL_01280 3.55e-51 - - - S - - - Protein of unknown function (DUF1071)
GEMNEGCL_01284 1.08e-05 - - - K - - - Helix-turn-helix domain
GEMNEGCL_01288 9.34e-109 - - - S - - - DNA binding
GEMNEGCL_01291 8.77e-22 - - - K - - - Cro/C1-type HTH DNA-binding domain
GEMNEGCL_01294 2.37e-13 - - - S - - - Membrane
GEMNEGCL_01295 2.57e-225 - - - L - - - Belongs to the 'phage' integrase family
GEMNEGCL_01296 1.57e-275 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GEMNEGCL_01297 4.13e-38 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GEMNEGCL_01299 2.23e-189 - - - S - - - Putative ABC-transporter type IV
GEMNEGCL_01301 4.11e-124 potE - - E - - - thought to be involved in transport amino acids across the membrane
GEMNEGCL_01303 2.67e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GEMNEGCL_01304 6.66e-27 - - - S - - - CAAX protease self-immunity
GEMNEGCL_01306 1.25e-94 - - - K - - - Helix-turn-helix domain
GEMNEGCL_01307 2.72e-15 - - - - - - - -
GEMNEGCL_01308 4.56e-78 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
GEMNEGCL_01309 1.32e-74 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GEMNEGCL_01310 1.33e-165 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
GEMNEGCL_01311 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GEMNEGCL_01312 2.49e-117 alkD - - L - - - DNA alkylation repair enzyme
GEMNEGCL_01313 7.39e-225 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
GEMNEGCL_01314 3.85e-109 - - - - - - - -
GEMNEGCL_01315 3.04e-53 - - - C - - - FMN_bind
GEMNEGCL_01316 0.0 - - - I - - - Protein of unknown function (DUF2974)
GEMNEGCL_01317 4.2e-249 pbpX1 - - V - - - Beta-lactamase
GEMNEGCL_01318 1.05e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GEMNEGCL_01319 7.42e-276 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GEMNEGCL_01320 6.89e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GEMNEGCL_01321 3.66e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEMNEGCL_01322 8.08e-281 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GEMNEGCL_01323 8.62e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GEMNEGCL_01324 1.39e-312 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GEMNEGCL_01325 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GEMNEGCL_01326 6.25e-246 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GEMNEGCL_01327 1.27e-220 potE - - E - - - Amino Acid
GEMNEGCL_01328 2.58e-48 potE - - E - - - Amino Acid
GEMNEGCL_01329 1.59e-136 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GEMNEGCL_01330 3.04e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GEMNEGCL_01331 1.09e-292 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GEMNEGCL_01332 5.76e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GEMNEGCL_01333 5.43e-191 - - - - - - - -
GEMNEGCL_01334 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GEMNEGCL_01335 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GEMNEGCL_01336 6.28e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GEMNEGCL_01337 2.57e-226 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GEMNEGCL_01338 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GEMNEGCL_01339 2.7e-126 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
GEMNEGCL_01340 1.16e-243 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GEMNEGCL_01341 2.88e-106 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GEMNEGCL_01342 2.12e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
GEMNEGCL_01343 9.94e-71 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
GEMNEGCL_01344 9.6e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GEMNEGCL_01345 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GEMNEGCL_01346 9.73e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GEMNEGCL_01347 1.27e-311 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GEMNEGCL_01348 8.12e-60 yitW - - S - - - Iron-sulfur cluster assembly protein
GEMNEGCL_01349 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
GEMNEGCL_01350 6.98e-78 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
GEMNEGCL_01351 1.39e-224 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GEMNEGCL_01352 6.22e-232 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
GEMNEGCL_01353 4.43e-179 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
GEMNEGCL_01354 1.51e-154 - - - C - - - 2Fe-2S iron-sulfur cluster binding domain
GEMNEGCL_01355 1.24e-188 - 5.2.1.13 - Q ko:K09835 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
GEMNEGCL_01356 7.13e-67 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
GEMNEGCL_01357 5.71e-230 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
GEMNEGCL_01358 2.36e-213 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GEMNEGCL_01359 2.24e-71 ykoJ - - S - - - Peptidase propeptide and YPEB domain
GEMNEGCL_01360 1.5e-176 - - - L - - - An automated process has identified a potential problem with this gene model
GEMNEGCL_01362 3.68e-176 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GEMNEGCL_01363 3.05e-110 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GEMNEGCL_01364 3.61e-288 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GEMNEGCL_01365 1.91e-103 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GEMNEGCL_01366 2.43e-118 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GEMNEGCL_01367 1.16e-13 - - - L - - - Psort location Cytoplasmic, score
GEMNEGCL_01368 1.04e-211 - - - S - - - Protein of unknown function (DUF2974)
GEMNEGCL_01369 8.58e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEMNEGCL_01370 7.42e-123 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEMNEGCL_01371 1.5e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_01372 1.19e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_01373 6.42e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
GEMNEGCL_01374 6.3e-191 - - - G - - - MFS/sugar transport protein
GEMNEGCL_01375 1.34e-106 - - - G - - - MFS/sugar transport protein
GEMNEGCL_01376 7.3e-131 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GEMNEGCL_01377 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
GEMNEGCL_01378 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_01379 2.53e-106 - - - K - - - Transcriptional regulator, MarR family
GEMNEGCL_01380 2.05e-188 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEMNEGCL_01381 6.43e-167 - - - F - - - glutamine amidotransferase
GEMNEGCL_01382 3.41e-312 steT - - E ko:K03294 - ko00000 amino acid
GEMNEGCL_01383 7.64e-307 steT - - E ko:K03294 - ko00000 amino acid
GEMNEGCL_01384 1.13e-177 - - - - - - - -
GEMNEGCL_01385 8.85e-121 - - - M - - - LysM domain protein
GEMNEGCL_01386 6.42e-110 - - - C - - - Aldo keto reductase
GEMNEGCL_01387 9.4e-232 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GEMNEGCL_01388 1.4e-313 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GEMNEGCL_01389 4.67e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GEMNEGCL_01390 5.99e-180 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
GEMNEGCL_01391 8.35e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GEMNEGCL_01392 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GEMNEGCL_01393 1.5e-195 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GEMNEGCL_01394 1e-168 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GEMNEGCL_01395 2.15e-198 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GEMNEGCL_01396 2.4e-118 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
GEMNEGCL_01397 7.2e-49 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
GEMNEGCL_01398 3.67e-88 - - - P - - - NhaP-type Na H and K H
GEMNEGCL_01399 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
GEMNEGCL_01400 8.83e-187 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
GEMNEGCL_01401 1.8e-143 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
GEMNEGCL_01402 5.13e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GEMNEGCL_01403 1.15e-205 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GEMNEGCL_01404 9.58e-112 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
GEMNEGCL_01405 6.08e-161 yagE - - E - - - Amino acid permease
GEMNEGCL_01406 8.49e-85 - - - E - - - amino acid
GEMNEGCL_01407 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GEMNEGCL_01408 2.09e-129 treR - - K ko:K03486 - ko00000,ko03000 UTRA
GEMNEGCL_01409 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GEMNEGCL_01410 2.76e-86 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GEMNEGCL_01411 1.13e-241 - - - L ko:K07478 - ko00000 AAA C-terminal domain
GEMNEGCL_01412 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GEMNEGCL_01413 5.74e-108 - - - K - - - Acetyltransferase (GNAT) domain
GEMNEGCL_01414 1.87e-290 - - - S - - - Putative peptidoglycan binding domain
GEMNEGCL_01415 7.89e-124 - - - S - - - ECF-type riboflavin transporter, S component
GEMNEGCL_01416 3.1e-127 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
GEMNEGCL_01417 1.59e-259 pbpX1 - - V - - - Beta-lactamase
GEMNEGCL_01418 1.12e-149 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GEMNEGCL_01419 1.12e-104 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GEMNEGCL_01420 3.57e-170 - - - L - - - Phage integrase family
GEMNEGCL_01421 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GEMNEGCL_01422 3.22e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GEMNEGCL_01423 1.06e-185 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GEMNEGCL_01424 5.12e-174 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GEMNEGCL_01425 5.5e-202 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GEMNEGCL_01426 1.02e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GEMNEGCL_01427 2.23e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GEMNEGCL_01428 3.62e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GEMNEGCL_01429 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GEMNEGCL_01430 3.44e-72 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GEMNEGCL_01431 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GEMNEGCL_01432 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GEMNEGCL_01433 3.7e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GEMNEGCL_01434 1.25e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GEMNEGCL_01435 4.95e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GEMNEGCL_01436 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GEMNEGCL_01437 3.73e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GEMNEGCL_01438 2.8e-72 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GEMNEGCL_01439 7.18e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GEMNEGCL_01440 7.94e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GEMNEGCL_01441 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GEMNEGCL_01442 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GEMNEGCL_01443 3.03e-44 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GEMNEGCL_01444 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GEMNEGCL_01445 1.56e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GEMNEGCL_01446 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GEMNEGCL_01447 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GEMNEGCL_01448 8.7e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GEMNEGCL_01449 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GEMNEGCL_01450 1.14e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GEMNEGCL_01451 4.01e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GEMNEGCL_01452 1.14e-63 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GEMNEGCL_01453 4.68e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GEMNEGCL_01454 6.64e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GEMNEGCL_01455 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GEMNEGCL_01456 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GEMNEGCL_01457 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GEMNEGCL_01458 1.47e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GEMNEGCL_01459 7.71e-157 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
GEMNEGCL_01460 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GEMNEGCL_01461 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GEMNEGCL_01462 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GEMNEGCL_01463 1.92e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
GEMNEGCL_01467 2.84e-108 - - - K - - - FR47-like protein
GEMNEGCL_01468 6.6e-219 - - - L - - - Bifunctional protein
GEMNEGCL_01470 1.1e-128 - - - E ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GEMNEGCL_01471 6.18e-123 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
GEMNEGCL_01472 1.07e-93 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GEMNEGCL_01473 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GEMNEGCL_01474 8.69e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GEMNEGCL_01475 1.52e-193 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEMNEGCL_01476 5.81e-253 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GEMNEGCL_01477 6.85e-109 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
GEMNEGCL_01478 5.03e-256 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
GEMNEGCL_01479 1.77e-157 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GEMNEGCL_01480 9.22e-141 yqeK - - H - - - Hydrolase, HD family
GEMNEGCL_01481 5.09e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GEMNEGCL_01482 8.01e-276 ylbM - - S - - - Belongs to the UPF0348 family
GEMNEGCL_01483 2.19e-125 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
GEMNEGCL_01484 3.52e-163 csrR - - K - - - response regulator
GEMNEGCL_01485 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GEMNEGCL_01486 2.19e-18 - - - - - - - -
GEMNEGCL_01487 4.28e-125 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GEMNEGCL_01488 2.95e-283 - - - S - - - SLAP domain
GEMNEGCL_01489 3.23e-108 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
GEMNEGCL_01490 2.43e-216 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GEMNEGCL_01491 1.32e-57 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GEMNEGCL_01492 1.37e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GEMNEGCL_01493 3.71e-76 yodB - - K - - - Transcriptional regulator, HxlR family
GEMNEGCL_01495 5.18e-139 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
GEMNEGCL_01496 1.68e-149 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
GEMNEGCL_01497 4.57e-163 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_01498 3.72e-202 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_01499 2.9e-254 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GEMNEGCL_01500 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GEMNEGCL_01501 2.55e-94 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GEMNEGCL_01502 6.74e-214 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
GEMNEGCL_01503 2.91e-181 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GEMNEGCL_01504 1.8e-34 - - - - - - - -
GEMNEGCL_01505 0.0 sufI - - Q - - - Multicopper oxidase
GEMNEGCL_01506 1.76e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
GEMNEGCL_01507 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEMNEGCL_01508 8.29e-294 - - - Q - - - Imidazolonepropionase and related amidohydrolases
GEMNEGCL_01509 2.48e-313 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
GEMNEGCL_01510 1.3e-175 - - - S - - - Protein of unknown function (DUF3100)
GEMNEGCL_01511 2.04e-60 - - - S - - - An automated process has identified a potential problem with this gene model
GEMNEGCL_01512 6.91e-67 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GEMNEGCL_01513 1.29e-164 - - - S - - - SLAP domain
GEMNEGCL_01514 3.66e-43 - - - - - - - -
GEMNEGCL_01515 7.51e-145 - - - K - - - WHG domain
GEMNEGCL_01516 3.41e-125 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
GEMNEGCL_01517 2.58e-126 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
GEMNEGCL_01518 9.48e-194 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GEMNEGCL_01519 5.24e-230 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GEMNEGCL_01521 2.99e-75 cvpA - - S - - - Colicin V production protein
GEMNEGCL_01522 3.66e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
GEMNEGCL_01523 5.86e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GEMNEGCL_01524 4.99e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
GEMNEGCL_01525 4.28e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GEMNEGCL_01526 4.49e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
GEMNEGCL_01527 6.88e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GEMNEGCL_01528 3.93e-176 - - - S - - - Protein of unknown function (DUF1129)
GEMNEGCL_01529 1.22e-190 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_01530 1.68e-179 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_01531 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
GEMNEGCL_01532 8.32e-157 vanR - - K - - - response regulator
GEMNEGCL_01533 2.18e-269 - - - T - - - His Kinase A (phosphoacceptor) domain
GEMNEGCL_01534 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GEMNEGCL_01535 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GEMNEGCL_01536 6.94e-70 - - - S - - - Enterocin A Immunity
GEMNEGCL_01537 1.95e-45 - - - - - - - -
GEMNEGCL_01538 1.07e-35 - - - - - - - -
GEMNEGCL_01539 4.48e-34 - - - - - - - -
GEMNEGCL_01540 1.72e-127 - - - M - - - Protein of unknown function (DUF3737)
GEMNEGCL_01541 1.72e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
GEMNEGCL_01542 1.93e-242 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GEMNEGCL_01543 9.01e-90 - - - S - - - SdpI/YhfL protein family
GEMNEGCL_01544 4.96e-167 - - - K - - - Transcriptional regulatory protein, C terminal
GEMNEGCL_01545 0.0 yclK - - T - - - Histidine kinase
GEMNEGCL_01546 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GEMNEGCL_01547 5.3e-137 vanZ - - V - - - VanZ like family
GEMNEGCL_01548 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GEMNEGCL_01549 1.33e-273 - - - EGP - - - Major Facilitator
GEMNEGCL_01550 7.95e-250 ampC - - V - - - Beta-lactamase
GEMNEGCL_01553 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
GEMNEGCL_01554 7.02e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GEMNEGCL_01555 6.6e-237 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GEMNEGCL_01556 1.24e-198 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GEMNEGCL_01557 1.66e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GEMNEGCL_01558 5.28e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GEMNEGCL_01559 5.87e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GEMNEGCL_01560 4.83e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GEMNEGCL_01561 2.48e-83 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GEMNEGCL_01562 5.38e-119 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GEMNEGCL_01563 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GEMNEGCL_01564 1.48e-221 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GEMNEGCL_01565 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GEMNEGCL_01566 2.45e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GEMNEGCL_01567 2.54e-42 - - - S - - - Protein of unknown function (DUF1146)
GEMNEGCL_01568 4.81e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
GEMNEGCL_01569 1.59e-68 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
GEMNEGCL_01570 5.13e-46 - - - S - - - Protein of unknown function (DUF2969)
GEMNEGCL_01571 1.18e-275 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GEMNEGCL_01572 9.45e-104 uspA - - T - - - universal stress protein
GEMNEGCL_01573 1.35e-56 - - - - - - - -
GEMNEGCL_01574 1.47e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
GEMNEGCL_01575 8.08e-110 - - - S - - - Protein of unknown function (DUF1694)
GEMNEGCL_01576 3.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GEMNEGCL_01577 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GEMNEGCL_01578 1.13e-272 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GEMNEGCL_01579 2.86e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GEMNEGCL_01580 2.1e-232 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
GEMNEGCL_01581 6.01e-153 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GEMNEGCL_01582 3.97e-57 - - - S - - - PD-(D/E)XK nuclease family transposase
GEMNEGCL_01583 1.06e-86 - - - S - - - GtrA-like protein
GEMNEGCL_01584 1.73e-219 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
GEMNEGCL_01585 3.33e-123 - - - S - - - Protein of unknown function (DUF3990)
GEMNEGCL_01586 2.09e-59 - - - - - - - -
GEMNEGCL_01587 9.25e-13 - - - S - - - PD-(D/E)XK nuclease family transposase
GEMNEGCL_01588 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GEMNEGCL_01589 1.73e-165 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
GEMNEGCL_01590 2.91e-67 - - - - - - - -
GEMNEGCL_01591 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GEMNEGCL_01592 1.22e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GEMNEGCL_01593 1.06e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
GEMNEGCL_01594 6.18e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
GEMNEGCL_01595 8.26e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
GEMNEGCL_01596 8.27e-189 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GEMNEGCL_01597 5.43e-122 mreD - - - ko:K03571 - ko00000,ko03036 -
GEMNEGCL_01598 1.4e-09 - - - S - - - Protein of unknown function (DUF4044)
GEMNEGCL_01599 1.02e-72 - - - S - - - Protein of unknown function (DUF3397)
GEMNEGCL_01600 5.63e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GEMNEGCL_01601 1.49e-223 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GEMNEGCL_01602 6.55e-72 ftsL - - D - - - Cell division protein FtsL
GEMNEGCL_01603 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GEMNEGCL_01604 4.43e-224 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GEMNEGCL_01605 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GEMNEGCL_01606 1.65e-265 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GEMNEGCL_01607 3.14e-194 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GEMNEGCL_01608 1.91e-314 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GEMNEGCL_01609 2.52e-300 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GEMNEGCL_01610 1.43e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GEMNEGCL_01611 2.42e-60 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
GEMNEGCL_01612 1.9e-190 ylmH - - S - - - S4 domain protein
GEMNEGCL_01613 6.3e-138 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
GEMNEGCL_01614 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GEMNEGCL_01615 2.32e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
GEMNEGCL_01616 4.26e-133 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GEMNEGCL_01617 7.05e-55 - - - - - - - -
GEMNEGCL_01618 2.05e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GEMNEGCL_01619 1.62e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GEMNEGCL_01620 9.98e-75 XK27_04120 - - S - - - Putative amino acid metabolism
GEMNEGCL_01621 4.47e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GEMNEGCL_01622 4.7e-163 pgm - - G - - - Phosphoglycerate mutase family
GEMNEGCL_01623 2.31e-148 - - - S - - - repeat protein
GEMNEGCL_01624 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GEMNEGCL_01625 0.0 - - - L - - - Nuclease-related domain
GEMNEGCL_01626 3.07e-235 ytlR - - I - - - Diacylglycerol kinase catalytic domain
GEMNEGCL_01627 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GEMNEGCL_01628 5.22e-45 ykzG - - S - - - Belongs to the UPF0356 family
GEMNEGCL_01629 9.67e-104 - - - - - - - -
GEMNEGCL_01630 6.74e-309 cpdA - - S - - - Calcineurin-like phosphoesterase
GEMNEGCL_01631 5.87e-278 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GEMNEGCL_01632 1.85e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GEMNEGCL_01633 1.18e-139 ypsA - - S - - - Belongs to the UPF0398 family
GEMNEGCL_01634 8.47e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GEMNEGCL_01635 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
GEMNEGCL_01636 2.24e-147 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GEMNEGCL_01637 6.91e-149 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
GEMNEGCL_01638 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
GEMNEGCL_01639 9.62e-116 ypmB - - S - - - Protein conserved in bacteria
GEMNEGCL_01640 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GEMNEGCL_01641 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GEMNEGCL_01642 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GEMNEGCL_01643 2.12e-173 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
GEMNEGCL_01644 5.87e-228 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
GEMNEGCL_01645 6.67e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
GEMNEGCL_01646 4.87e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GEMNEGCL_01647 1.28e-150 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
GEMNEGCL_01648 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
GEMNEGCL_01649 4.4e-215 - - - - - - - -
GEMNEGCL_01650 4.01e-184 - - - - - - - -
GEMNEGCL_01651 1.27e-133 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GEMNEGCL_01652 3.49e-36 - - - - - - - -
GEMNEGCL_01653 3.85e-193 - - - - - - - -
GEMNEGCL_01654 9.63e-50 - - - - - - - -
GEMNEGCL_01655 5.91e-113 - - - - - - - -
GEMNEGCL_01656 1.65e-180 - - - - - - - -
GEMNEGCL_01657 5.4e-161 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GEMNEGCL_01658 1.25e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
GEMNEGCL_01659 2.86e-307 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GEMNEGCL_01660 8.12e-196 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GEMNEGCL_01661 2.8e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GEMNEGCL_01662 5.37e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
GEMNEGCL_01663 4.34e-166 - - - S - - - Peptidase family M23
GEMNEGCL_01664 2.85e-27 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_01665 3.39e-88 - - - S ko:K06915 - ko00000 cog cog0433
GEMNEGCL_01666 9.86e-146 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
GEMNEGCL_01667 8.81e-40 - - - M - - - Mycoplasma protein of unknown function, DUF285
GEMNEGCL_01669 1.61e-70 - - - - - - - -
GEMNEGCL_01670 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
GEMNEGCL_01671 9.07e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GEMNEGCL_01672 2.28e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GEMNEGCL_01673 4.13e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GEMNEGCL_01674 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GEMNEGCL_01675 0.0 FbpA - - K - - - Fibronectin-binding protein
GEMNEGCL_01676 2.06e-88 - - - - - - - -
GEMNEGCL_01677 2.23e-202 - - - S - - - EDD domain protein, DegV family
GEMNEGCL_01678 5.59e-98 - - - - - - - -
GEMNEGCL_01679 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GEMNEGCL_01680 1.31e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GEMNEGCL_01681 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
GEMNEGCL_01682 3.04e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GEMNEGCL_01683 2.16e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GEMNEGCL_01684 2.24e-198 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GEMNEGCL_01685 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GEMNEGCL_01686 1.05e-40 - - - - - - - -
GEMNEGCL_01687 1.72e-23 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_01688 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GEMNEGCL_01689 5.36e-289 - - - L - - - COG3547 Transposase and inactivated derivatives
GEMNEGCL_01690 4.76e-140 - - - - - - - -
GEMNEGCL_01691 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
GEMNEGCL_01692 1.53e-127 yobS - - K - - - Bacterial regulatory proteins, tetR family
GEMNEGCL_01693 1.33e-205 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
GEMNEGCL_01694 1.4e-207 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GEMNEGCL_01695 6.07e-310 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GEMNEGCL_01696 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
GEMNEGCL_01697 5.62e-187 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GEMNEGCL_01698 4.69e-202 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
GEMNEGCL_01699 8.72e-258 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
GEMNEGCL_01700 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GEMNEGCL_01701 7.24e-204 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GEMNEGCL_01702 1.83e-230 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
GEMNEGCL_01703 3.45e-201 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GEMNEGCL_01704 2.23e-150 yviA - - S - - - Protein of unknown function (DUF421)
GEMNEGCL_01705 2.94e-74 - - - S - - - Protein of unknown function (DUF3290)
GEMNEGCL_01706 3.6e-106 - - - C - - - Flavodoxin
GEMNEGCL_01707 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
GEMNEGCL_01708 2.25e-241 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
GEMNEGCL_01709 5.94e-148 - - - I - - - Acid phosphatase homologues
GEMNEGCL_01710 2.91e-103 - - - S - - - Phage portal protein
GEMNEGCL_01711 2.67e-95 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
GEMNEGCL_01712 7.4e-57 - - - S - - - Phage capsid family
GEMNEGCL_01713 1.2e-23 - - - S - - - Phage gp6-like head-tail connector protein
GEMNEGCL_01715 1.42e-23 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
GEMNEGCL_01720 9.77e-175 - - - L - - - Phage tail tape measure protein TP901
GEMNEGCL_01721 3.54e-36 - - - S - - - phage tail
GEMNEGCL_01722 2.37e-194 - - - S - - - Phage minor structural protein
GEMNEGCL_01729 7.99e-87 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GEMNEGCL_01730 3.01e-137 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GEMNEGCL_01731 1.71e-150 - - - S - - - Peptidase family M23
GEMNEGCL_01732 1.34e-34 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_01733 2.01e-32 - - - G - - - Peptidase_C39 like family
GEMNEGCL_01734 2.16e-207 - - - M - - - NlpC/P60 family
GEMNEGCL_01735 6.67e-115 - - - G - - - Peptidase_C39 like family
GEMNEGCL_01736 1.09e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GEMNEGCL_01737 2.05e-115 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GEMNEGCL_01738 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_01741 4.06e-132 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
GEMNEGCL_01742 8.32e-171 - - - - - - - -
GEMNEGCL_01743 3.18e-126 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GEMNEGCL_01744 7.4e-188 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
GEMNEGCL_01745 2.96e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GEMNEGCL_01746 3.09e-71 - - - - - - - -
GEMNEGCL_01747 5.62e-95 yslB - - S - - - Protein of unknown function (DUF2507)
GEMNEGCL_01748 2.91e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GEMNEGCL_01749 8.12e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GEMNEGCL_01750 1.06e-38 - - - - - - - -
GEMNEGCL_01752 1.02e-19 - - - S - - - Phage portal protein
GEMNEGCL_01754 8.56e-221 - - - S - - - Phage Terminase
GEMNEGCL_01755 1.84e-38 - - - S - - - Phage Terminase
GEMNEGCL_01758 9.87e-71 - - - L - - - Phage terminase, small subunit
GEMNEGCL_01759 3.73e-80 - - - L - - - HNH nucleases
GEMNEGCL_01760 2.55e-09 - - - - - - - -
GEMNEGCL_01766 1.21e-106 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
GEMNEGCL_01772 9.66e-13 - - - - - - - -
GEMNEGCL_01775 5.65e-23 - - - L - - - Psort location Cytoplasmic, score
GEMNEGCL_01783 2.86e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
GEMNEGCL_01784 5.53e-95 - - - K - - - Peptidase S24-like
GEMNEGCL_01785 1.25e-24 - - - S - - - Hypothetical protein (DUF2513)
GEMNEGCL_01788 8.96e-231 - - - V - - - Abi-like protein
GEMNEGCL_01789 4.87e-154 - - - L - - - Belongs to the 'phage' integrase family
GEMNEGCL_01790 2.48e-12 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GEMNEGCL_01792 2.83e-205 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GEMNEGCL_01793 1.34e-151 - - - - - - - -
GEMNEGCL_01794 3.06e-202 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GEMNEGCL_01795 2.95e-283 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GEMNEGCL_01796 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
GEMNEGCL_01797 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GEMNEGCL_01798 6.83e-133 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
GEMNEGCL_01799 0.0 - - - L - - - PLD-like domain
GEMNEGCL_01800 5.97e-55 - - - S - - - SnoaL-like domain
GEMNEGCL_01801 6.13e-70 - - - K - - - sequence-specific DNA binding
GEMNEGCL_01802 8.71e-31 - - - G - - - Ribose/Galactose Isomerase
GEMNEGCL_01803 5.51e-35 - - - - - - - -
GEMNEGCL_01804 8.1e-87 - - - S - - - Domain of unknown function DUF1828
GEMNEGCL_01805 7.91e-14 - - - - - - - -
GEMNEGCL_01806 2.93e-67 - - - - - - - -
GEMNEGCL_01807 1.05e-226 citR - - K - - - Putative sugar-binding domain
GEMNEGCL_01808 0.0 - - - S - - - Putative threonine/serine exporter
GEMNEGCL_01810 1.13e-45 - - - - - - - -
GEMNEGCL_01811 7.7e-21 - - - - - - - -
GEMNEGCL_01812 1.85e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GEMNEGCL_01813 1.38e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
GEMNEGCL_01814 6.77e-49 - - - - - - - -
GEMNEGCL_01815 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GEMNEGCL_01816 1.8e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GEMNEGCL_01817 2.03e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GEMNEGCL_01818 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GEMNEGCL_01819 9.14e-283 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GEMNEGCL_01821 3.82e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GEMNEGCL_01822 1.19e-43 - - - S - - - reductase
GEMNEGCL_01823 2.98e-50 - - - S - - - reductase
GEMNEGCL_01824 6.32e-41 - - - S - - - reductase
GEMNEGCL_01825 2.13e-189 yxeH - - S - - - hydrolase
GEMNEGCL_01826 1.14e-230 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEMNEGCL_01827 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
GEMNEGCL_01828 1.58e-140 yngC - - S - - - SNARE associated Golgi protein
GEMNEGCL_01829 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GEMNEGCL_01830 1.88e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GEMNEGCL_01831 0.0 oatA - - I - - - Acyltransferase
GEMNEGCL_01832 6.82e-223 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GEMNEGCL_01833 6.84e-183 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GEMNEGCL_01834 3.57e-47 - - - S - - - Lipopolysaccharide assembly protein A domain
GEMNEGCL_01835 5.14e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GEMNEGCL_01836 2.22e-166 - - - L - - - Belongs to the 'phage' integrase family
GEMNEGCL_01839 1.29e-32 - - - S - - - Hypothetical protein (DUF2513)
GEMNEGCL_01841 1.8e-20 - - - K - - - Helix-turn-helix XRE-family like proteins
GEMNEGCL_01844 1.7e-23 - - - - - - - -
GEMNEGCL_01845 6.73e-97 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
GEMNEGCL_01852 2.83e-90 - - - S - - - AAA domain
GEMNEGCL_01854 9.75e-189 - - - L - - - Helicase C-terminal domain protein
GEMNEGCL_01857 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
GEMNEGCL_01869 2.71e-49 - - - S - - - VRR_NUC
GEMNEGCL_01872 3.2e-61 - - - S - - - HNH endonuclease
GEMNEGCL_01873 1.71e-72 - - - S - - - Phage terminase, small subunit
GEMNEGCL_01875 1.06e-264 - - - S - - - Phage Terminase
GEMNEGCL_01877 5.08e-161 - - - S - - - Phage portal protein
GEMNEGCL_01878 7.51e-51 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
GEMNEGCL_01879 4.16e-150 - - - S - - - peptidase activity
GEMNEGCL_01887 2e-202 - - - D - - - domain protein
GEMNEGCL_01889 1.49e-162 - - - S - - - Phage minor structural protein
GEMNEGCL_01898 5.77e-39 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
GEMNEGCL_01899 5.45e-106 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
GEMNEGCL_01901 9.67e-15 - - - - - - - -
GEMNEGCL_01902 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GEMNEGCL_01903 1.25e-38 - - - S - - - Protein of unknown function (DUF2929)
GEMNEGCL_01904 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GEMNEGCL_01905 5.46e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GEMNEGCL_01906 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GEMNEGCL_01907 1.21e-213 yitL - - S ko:K00243 - ko00000 S1 domain
GEMNEGCL_01908 6.74e-213 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
GEMNEGCL_01909 3.25e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GEMNEGCL_01910 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GEMNEGCL_01911 7.57e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GEMNEGCL_01912 4.65e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GEMNEGCL_01913 8.49e-146 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GEMNEGCL_01914 1.13e-41 - - - M - - - Lysin motif
GEMNEGCL_01915 5.6e-148 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GEMNEGCL_01916 1.4e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GEMNEGCL_01917 1.34e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GEMNEGCL_01918 8.21e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GEMNEGCL_01919 7.11e-293 XK27_05225 - - S - - - Tetratricopeptide repeat protein
GEMNEGCL_01920 2e-299 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEMNEGCL_01921 8.88e-178 - - - P - - - Voltage gated chloride channel
GEMNEGCL_01922 3.44e-238 - - - C - - - FMN-dependent dehydrogenase
GEMNEGCL_01923 8.68e-69 - - - - - - - -
GEMNEGCL_01924 1.17e-56 - - - - - - - -
GEMNEGCL_01925 1.33e-295 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GEMNEGCL_01926 0.0 - - - E - - - amino acid
GEMNEGCL_01927 1.64e-200 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
GEMNEGCL_01928 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
GEMNEGCL_01929 1.07e-52 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GEMNEGCL_01930 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GEMNEGCL_01931 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GEMNEGCL_01932 9.39e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GEMNEGCL_01933 1.55e-274 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GEMNEGCL_01934 1.23e-166 - - - S - - - (CBS) domain
GEMNEGCL_01935 2.93e-234 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GEMNEGCL_01936 1.89e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GEMNEGCL_01937 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GEMNEGCL_01938 7.32e-46 yabO - - J - - - S4 domain protein
GEMNEGCL_01939 7.52e-78 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GEMNEGCL_01940 1.61e-81 - - - J ko:K07571 - ko00000 S1 RNA binding domain
GEMNEGCL_01941 3.35e-308 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GEMNEGCL_01942 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GEMNEGCL_01943 3.91e-214 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GEMNEGCL_01944 2.77e-248 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GEMNEGCL_01945 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GEMNEGCL_01946 1.06e-247 - - - S - - - Uncharacterised protein family (UPF0236)
GEMNEGCL_01947 8.64e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GEMNEGCL_01948 3.17e-224 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
GEMNEGCL_01949 1.19e-188 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
GEMNEGCL_01950 7.44e-192 yycI - - S - - - YycH protein
GEMNEGCL_01951 0.0 yycH - - S - - - YycH protein
GEMNEGCL_01952 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GEMNEGCL_01953 3.98e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GEMNEGCL_01955 4.42e-87 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEMNEGCL_01956 2.95e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEMNEGCL_01957 1.31e-16 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
GEMNEGCL_01958 3.03e-145 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GEMNEGCL_01959 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
GEMNEGCL_01960 9.58e-122 - - - C - - - Pyridoxamine 5'-phosphate oxidase
GEMNEGCL_01961 0.0 - - - E - - - Amino acid permease
GEMNEGCL_01962 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
GEMNEGCL_01963 1.43e-310 ynbB - - P - - - aluminum resistance
GEMNEGCL_01964 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
GEMNEGCL_01965 1.51e-198 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
GEMNEGCL_01966 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
GEMNEGCL_01967 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
GEMNEGCL_01968 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
GEMNEGCL_01969 1.89e-23 - - - - - - - -
GEMNEGCL_01970 7.34e-178 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GEMNEGCL_01971 2.08e-164 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GEMNEGCL_01972 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GEMNEGCL_01973 7.86e-138 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
GEMNEGCL_01974 5.02e-180 blpT - - - - - - -
GEMNEGCL_01978 7.87e-30 - - - - - - - -
GEMNEGCL_01979 4.74e-107 - - - - - - - -
GEMNEGCL_01980 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
GEMNEGCL_01981 2.52e-32 - - - - - - - -
GEMNEGCL_01982 3.41e-88 - - - - - - - -
GEMNEGCL_01983 3.09e-212 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_01984 6.39e-279 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GEMNEGCL_01985 3.14e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
GEMNEGCL_01986 2.18e-215 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GEMNEGCL_01987 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
GEMNEGCL_01988 4.47e-56 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
GEMNEGCL_01989 2.96e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GEMNEGCL_01990 1.63e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GEMNEGCL_01991 1.59e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
GEMNEGCL_01992 5.22e-226 - - - S - - - PFAM Archaeal ATPase
GEMNEGCL_01993 2.85e-27 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_01994 6.16e-14 - - - - - - - -
GEMNEGCL_01995 5.45e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GEMNEGCL_01996 2.77e-135 - - - K ko:K06977 - ko00000 acetyltransferase
GEMNEGCL_01998 7.26e-287 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GEMNEGCL_01999 1.52e-105 - - - L - - - MgsA AAA+ ATPase C terminal
GEMNEGCL_02000 1.88e-132 - - - K - - - Helix-turn-helix domain, rpiR family
GEMNEGCL_02001 1.47e-243 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GEMNEGCL_02002 3.05e-184 epsB - - M - - - biosynthesis protein
GEMNEGCL_02003 5.61e-160 ywqD - - D - - - Capsular exopolysaccharide family
GEMNEGCL_02004 6.64e-186 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
GEMNEGCL_02005 1.26e-41 epsE2 - - M - - - Bacterial sugar transferase
GEMNEGCL_02006 7.59e-97 epsE2 - - M - - - Bacterial sugar transferase
GEMNEGCL_02007 1.68e-199 - - - M - - - Glycosyltransferase
GEMNEGCL_02008 1.53e-102 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
GEMNEGCL_02009 4.88e-98 - - - S - - - Glycosyltransferase family 28 C-terminal domain
GEMNEGCL_02010 2.38e-130 - - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GEMNEGCL_02011 2.56e-66 - - - M - - - Domain of unknown function (DUF1919)
GEMNEGCL_02012 5.18e-109 - - - M - - - Glycosyltransferase like family 2
GEMNEGCL_02013 2.94e-94 - - - S - - - Bacterial transferase hexapeptide (six repeats)
GEMNEGCL_02015 5.03e-76 - - - K - - - Helix-turn-helix domain
GEMNEGCL_02016 1.17e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GEMNEGCL_02017 1.05e-221 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
GEMNEGCL_02018 1.11e-234 - - - K - - - Transcriptional regulator
GEMNEGCL_02019 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GEMNEGCL_02020 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GEMNEGCL_02021 9.39e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GEMNEGCL_02022 0.0 snf - - KL - - - domain protein
GEMNEGCL_02023 2.9e-48 - - - - - - - -
GEMNEGCL_02024 1.24e-08 - - - - - - - -
GEMNEGCL_02025 4.83e-136 pncA - - Q - - - Isochorismatase family
GEMNEGCL_02026 1.51e-159 - - - - - - - -
GEMNEGCL_02029 4.13e-83 - - - - - - - -
GEMNEGCL_02030 3.56e-47 - - - - - - - -
GEMNEGCL_02031 4.07e-245 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GEMNEGCL_02032 1.5e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
GEMNEGCL_02033 4.57e-135 - - - S ko:K06872 - ko00000 TPM domain
GEMNEGCL_02034 1.71e-173 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GEMNEGCL_02035 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GEMNEGCL_02036 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GEMNEGCL_02037 2.72e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
GEMNEGCL_02038 5.17e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GEMNEGCL_02039 8.93e-194 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GEMNEGCL_02040 9.99e-53 veg - - S - - - Biofilm formation stimulator VEG
GEMNEGCL_02041 2.05e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GEMNEGCL_02042 1.81e-307 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GEMNEGCL_02044 6.45e-93 - - - K - - - LytTr DNA-binding domain
GEMNEGCL_02045 1.05e-119 - - - S - - - membrane
GEMNEGCL_02046 2.61e-23 - - - - - - - -
GEMNEGCL_02047 7.9e-255 - - - S - - - Putative peptidoglycan binding domain
GEMNEGCL_02051 7.95e-61 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GEMNEGCL_02052 3.82e-149 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GEMNEGCL_02053 5.14e-264 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_02054 1.82e-135 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_02055 4.4e-226 ydbI - - K - - - AI-2E family transporter
GEMNEGCL_02056 3.93e-134 - - - E - - - GDSL-like Lipase/Acylhydrolase
GEMNEGCL_02057 2.55e-26 - - - - - - - -
GEMNEGCL_02058 1.59e-315 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GEMNEGCL_02059 8.64e-176 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_02060 4.76e-168 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GEMNEGCL_02061 3.35e-223 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GEMNEGCL_02062 7.75e-170 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GEMNEGCL_02063 7.2e-202 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GEMNEGCL_02064 1.65e-205 yvgN - - C - - - Aldo keto reductase
GEMNEGCL_02065 0.0 fusA1 - - J - - - elongation factor G
GEMNEGCL_02066 3.16e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
GEMNEGCL_02067 1.07e-179 - - - EGP - - - Major Facilitator Superfamily
GEMNEGCL_02068 9.62e-247 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEMNEGCL_02069 1.44e-07 - - - S - - - YSIRK type signal peptide
GEMNEGCL_02071 1.2e-202 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GEMNEGCL_02072 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
GEMNEGCL_02073 0.0 - - - L - - - Helicase C-terminal domain protein
GEMNEGCL_02074 1.03e-258 pbpX - - V - - - Beta-lactamase
GEMNEGCL_02075 1.05e-289 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
GEMNEGCL_02076 4.19e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
GEMNEGCL_02077 3.61e-60 - - - - - - - -
GEMNEGCL_02078 4.53e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GEMNEGCL_02080 3.75e-48 - - - S - - - PFAM Archaeal ATPase
GEMNEGCL_02081 6.55e-97 - - - - - - - -
GEMNEGCL_02082 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
GEMNEGCL_02083 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GEMNEGCL_02084 6.15e-36 - - - - - - - -
GEMNEGCL_02085 5.31e-149 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
GEMNEGCL_02086 1.04e-187 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
GEMNEGCL_02087 1.61e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GEMNEGCL_02088 3.72e-111 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GEMNEGCL_02090 5.61e-118 - - - L - - - An automated process has identified a potential problem with this gene model
GEMNEGCL_02091 2.89e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GEMNEGCL_02092 3.83e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GEMNEGCL_02093 5.24e-187 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GEMNEGCL_02094 3.01e-197 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GEMNEGCL_02095 2.29e-210 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GEMNEGCL_02096 5.48e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GEMNEGCL_02097 1.05e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GEMNEGCL_02098 3.82e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GEMNEGCL_02099 1.23e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GEMNEGCL_02100 3.73e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GEMNEGCL_02101 1.1e-309 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GEMNEGCL_02102 1.52e-87 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GEMNEGCL_02103 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GEMNEGCL_02104 1.19e-45 - - - - - - - -
GEMNEGCL_02105 1.09e-122 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
GEMNEGCL_02106 1.56e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GEMNEGCL_02107 4.95e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GEMNEGCL_02108 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GEMNEGCL_02109 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GEMNEGCL_02110 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GEMNEGCL_02111 5.22e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
GEMNEGCL_02112 2.39e-136 - - - L - - - COG3547 Transposase and inactivated derivatives
GEMNEGCL_02113 5.34e-77 tnpR1 - - L - - - Resolvase, N terminal domain
GEMNEGCL_02114 1.01e-33 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GEMNEGCL_02115 7.44e-129 - - - L - - - An automated process has identified a potential problem with this gene model
GEMNEGCL_02116 7.01e-160 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GEMNEGCL_02117 2.26e-153 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
GEMNEGCL_02118 9.69e-177 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GEMNEGCL_02119 1.6e-220 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEMNEGCL_02120 2.2e-227 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GEMNEGCL_02121 5.15e-247 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GEMNEGCL_02122 4.4e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEMNEGCL_02123 3.69e-233 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GEMNEGCL_02124 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GEMNEGCL_02125 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
GEMNEGCL_02126 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
GEMNEGCL_02127 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GEMNEGCL_02128 3.12e-41 - - - - - - - -
GEMNEGCL_02129 3.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GEMNEGCL_02130 2.61e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GEMNEGCL_02131 1.03e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GEMNEGCL_02132 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GEMNEGCL_02133 1.98e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GEMNEGCL_02134 7.82e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GEMNEGCL_02135 5.15e-219 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GEMNEGCL_02136 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GEMNEGCL_02137 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GEMNEGCL_02138 5.97e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GEMNEGCL_02139 2.19e-100 - - - S - - - ASCH
GEMNEGCL_02140 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GEMNEGCL_02141 1.83e-190 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
GEMNEGCL_02142 4.47e-196 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GEMNEGCL_02143 4.4e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GEMNEGCL_02144 1.08e-238 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GEMNEGCL_02145 8.47e-182 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GEMNEGCL_02146 3.38e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GEMNEGCL_02147 7.98e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
GEMNEGCL_02148 2.11e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GEMNEGCL_02149 2.14e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GEMNEGCL_02150 3.94e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GEMNEGCL_02151 6.82e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GEMNEGCL_02152 5.24e-194 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GEMNEGCL_02153 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GEMNEGCL_02154 0.0 - - - L - - - Transposase
GEMNEGCL_02157 2.07e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
GEMNEGCL_02158 0.0 - - - S - - - Predicted membrane protein (DUF2207)
GEMNEGCL_02159 2.99e-202 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
GEMNEGCL_02160 5.27e-266 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GEMNEGCL_02162 3.02e-228 lipA - - I - - - Carboxylesterase family
GEMNEGCL_02163 1.82e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
GEMNEGCL_02164 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GEMNEGCL_02165 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GEMNEGCL_02166 6.92e-145 supH - - S - - - haloacid dehalogenase-like hydrolase
GEMNEGCL_02167 4.33e-69 - - - - - - - -
GEMNEGCL_02168 8.51e-50 - - - - - - - -
GEMNEGCL_02169 2.1e-82 - - - S - - - Alpha beta hydrolase
GEMNEGCL_02170 2.19e-49 - - - S - - - Alpha beta hydrolase
GEMNEGCL_02171 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GEMNEGCL_02172 2.88e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GEMNEGCL_02173 8.74e-62 - - - - - - - -
GEMNEGCL_02174 2.37e-190 - - - U ko:K05340 - ko00000,ko02000 sugar transport
GEMNEGCL_02175 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GEMNEGCL_02176 5.52e-113 - - - - - - - -
GEMNEGCL_02177 0.0 - - - S - - - SLAP domain
GEMNEGCL_02178 3.49e-222 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GEMNEGCL_02179 1.13e-218 - - - GK - - - ROK family
GEMNEGCL_02180 4.19e-57 - - - - - - - -
GEMNEGCL_02181 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GEMNEGCL_02182 1.33e-130 - - - M - - - LysM domain protein
GEMNEGCL_02183 5.68e-211 - - - D - - - nuclear chromosome segregation
GEMNEGCL_02184 8.92e-136 - - - G - - - Phosphoglycerate mutase family
GEMNEGCL_02185 9.01e-115 - - - G - - - Histidine phosphatase superfamily (branch 1)
GEMNEGCL_02186 1.9e-153 - - - G - - - Antibiotic biosynthesis monooxygenase
GEMNEGCL_02187 2.67e-148 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GEMNEGCL_02189 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GEMNEGCL_02191 1.93e-266 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GEMNEGCL_02192 1.03e-237 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
GEMNEGCL_02193 3.01e-154 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GEMNEGCL_02194 1.17e-185 - - - K - - - SIS domain
GEMNEGCL_02195 9.6e-309 slpX - - S - - - SLAP domain
GEMNEGCL_02196 5.24e-31 - - - S - - - transposase or invertase
GEMNEGCL_02197 1.48e-14 - - - - - - - -
GEMNEGCL_02198 7.62e-306 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
GEMNEGCL_02201 0.0 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GEMNEGCL_02202 1.53e-232 - - - - - - - -
GEMNEGCL_02203 1.87e-159 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
GEMNEGCL_02204 3.68e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
GEMNEGCL_02205 3.81e-275 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GEMNEGCL_02206 1.39e-160 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
GEMNEGCL_02207 3.75e-79 - - - - - - - -
GEMNEGCL_02208 6.04e-26 - - - - - - - -
GEMNEGCL_02209 4.4e-132 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GEMNEGCL_02210 2.52e-76 - - - - - - - -
GEMNEGCL_02211 0.0 - - - S - - - ABC transporter
GEMNEGCL_02212 7.35e-174 - - - S - - - Putative threonine/serine exporter
GEMNEGCL_02213 7.36e-109 - - - S - - - Threonine/Serine exporter, ThrE
GEMNEGCL_02214 1.58e-143 - - - S - - - Peptidase_C39 like family
GEMNEGCL_02215 1.16e-101 - - - - - - - -
GEMNEGCL_02216 1.96e-226 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GEMNEGCL_02217 4.75e-101 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
GEMNEGCL_02218 6.96e-286 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GEMNEGCL_02219 8.77e-144 - - - - - - - -
GEMNEGCL_02220 0.0 - - - S - - - O-antigen ligase like membrane protein
GEMNEGCL_02221 4.52e-56 - - - - - - - -
GEMNEGCL_02222 2.11e-115 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
GEMNEGCL_02223 4.39e-116 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
GEMNEGCL_02224 1.28e-174 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
GEMNEGCL_02225 1.73e-167 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
GEMNEGCL_02226 3.01e-54 - - - - - - - -
GEMNEGCL_02227 1.26e-223 - - - S - - - Cysteine-rich secretory protein family
GEMNEGCL_02228 1.3e-282 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GEMNEGCL_02232 9e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GEMNEGCL_02233 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GEMNEGCL_02234 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GEMNEGCL_02235 9.03e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GEMNEGCL_02236 4.11e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GEMNEGCL_02237 1.37e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GEMNEGCL_02238 3.58e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GEMNEGCL_02239 3.51e-224 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
GEMNEGCL_02240 1.08e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
GEMNEGCL_02241 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GEMNEGCL_02242 6.94e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GEMNEGCL_02243 1.34e-22 - - - S - - - CRISPR-associated protein (Cas_Csn2)
GEMNEGCL_02244 1.34e-34 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_02245 3.49e-50 - - - - - - - -
GEMNEGCL_02246 1.76e-233 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GEMNEGCL_02247 8.37e-161 - - - K - - - Bacterial regulatory proteins, tetR family
GEMNEGCL_02248 1.11e-177 - - - - - - - -
GEMNEGCL_02249 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GEMNEGCL_02250 1.01e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_02251 7.36e-291 - - - S - - - Cysteine-rich secretory protein family
GEMNEGCL_02252 2.43e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GEMNEGCL_02253 2.45e-164 - - - - - - - -
GEMNEGCL_02254 1.69e-258 yibE - - S - - - overlaps another CDS with the same product name
GEMNEGCL_02255 2.23e-166 yibF - - S - - - overlaps another CDS with the same product name
GEMNEGCL_02256 8.08e-201 - - - I - - - alpha/beta hydrolase fold
GEMNEGCL_02257 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GEMNEGCL_02258 3.75e-278 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GEMNEGCL_02259 1.42e-18 - - - - ko:K07473 - ko00000,ko02048 -
GEMNEGCL_02260 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GEMNEGCL_02261 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GEMNEGCL_02262 1.87e-58 - - - - - - - -
GEMNEGCL_02263 1.63e-159 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
GEMNEGCL_02264 1.56e-198 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GEMNEGCL_02265 1.6e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
GEMNEGCL_02266 3.32e-207 - - - L - - - Transposase
GEMNEGCL_02267 2.83e-115 - - - L - - - Transposase
GEMNEGCL_02268 5.17e-169 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GEMNEGCL_02269 4.78e-308 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
GEMNEGCL_02270 6.69e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GEMNEGCL_02271 0.0 potE - - E - - - Amino Acid
GEMNEGCL_02272 9.84e-63 - - - S - - - Fic/DOC family
GEMNEGCL_02274 0.0 - - - - - - - -
GEMNEGCL_02275 5.87e-110 - - - - - - - -
GEMNEGCL_02276 1.92e-113 yhaH - - S - - - Protein of unknown function (DUF805)
GEMNEGCL_02277 2.65e-89 - - - O - - - OsmC-like protein
GEMNEGCL_02278 5.3e-264 - - - EGP - - - Major Facilitator Superfamily
GEMNEGCL_02279 3e-290 sptS - - T - - - Histidine kinase
GEMNEGCL_02280 2.14e-85 dltr - - K - - - response regulator
GEMNEGCL_02281 4.52e-35 dltr - - K - - - response regulator
GEMNEGCL_02282 6.17e-140 - - - T - - - Region found in RelA / SpoT proteins
GEMNEGCL_02283 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
GEMNEGCL_02284 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
GEMNEGCL_02285 1.72e-268 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GEMNEGCL_02286 1.02e-195 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GEMNEGCL_02287 8.41e-202 msmF - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GEMNEGCL_02288 3.19e-302 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GEMNEGCL_02289 3.13e-206 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
GEMNEGCL_02290 2.14e-48 - - - - - - - -
GEMNEGCL_02291 8.29e-254 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
GEMNEGCL_02293 1.65e-303 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GEMNEGCL_02294 1.43e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
GEMNEGCL_02295 5.93e-302 XK27_01810 - - S - - - Calcineurin-like phosphoesterase
GEMNEGCL_02297 0.0 - - - S - - - SLAP domain
GEMNEGCL_02298 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
GEMNEGCL_02299 1.35e-208 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
GEMNEGCL_02300 5.22e-54 - - - S - - - RloB-like protein
GEMNEGCL_02301 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GEMNEGCL_02302 5.88e-118 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GEMNEGCL_02303 4.81e-77 - - - S - - - SIR2-like domain
GEMNEGCL_02305 1.28e-168 - - - L - - - PFAM transposase IS116 IS110 IS902
GEMNEGCL_02306 4.81e-228 - - - L - - - Transposase and inactivated derivatives, IS30 family
GEMNEGCL_02307 4.53e-209 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GEMNEGCL_02308 2.17e-174 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_02309 5.12e-178 - - - L - - - Transposase and inactivated derivatives, IS30 family
GEMNEGCL_02310 2.85e-27 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_02311 1.75e-10 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
GEMNEGCL_02312 2.27e-71 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
GEMNEGCL_02313 7.26e-35 - - - S - - - Protein conserved in bacteria
GEMNEGCL_02314 1.09e-74 - - - - - - - -
GEMNEGCL_02315 8.23e-112 - - - - - - - -
GEMNEGCL_02316 0.0 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
GEMNEGCL_02317 2.39e-182 - - - S - - - DUF218 domain
GEMNEGCL_02318 1.06e-141 - - - - - - - -
GEMNEGCL_02319 7.81e-107 - - - - - - - -
GEMNEGCL_02320 1.28e-106 yicL - - EG - - - EamA-like transporter family
GEMNEGCL_02321 6.7e-211 - - - EG - - - EamA-like transporter family
GEMNEGCL_02322 5.7e-209 - - - EG - - - EamA-like transporter family
GEMNEGCL_02323 2.52e-52 - - - - - - - -
GEMNEGCL_02324 1.15e-180 - - - L - - - An automated process has identified a potential problem with this gene model
GEMNEGCL_02326 4.26e-108 - - - M - - - NlpC/P60 family
GEMNEGCL_02327 1.51e-168 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
GEMNEGCL_02328 6.69e-84 - - - L - - - RelB antitoxin
GEMNEGCL_02329 4.91e-253 - - - V - - - ABC transporter transmembrane region
GEMNEGCL_02330 5.19e-248 - - - G - - - Transmembrane secretion effector
GEMNEGCL_02331 1.03e-262 - - - G - - - Glycosyl hydrolases family 8
GEMNEGCL_02332 3.25e-315 - - - M - - - Glycosyl transferase
GEMNEGCL_02334 9.39e-195 - - - - - - - -
GEMNEGCL_02335 2.13e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GEMNEGCL_02336 2.94e-261 - - - M - - - Glycosyl transferases group 1
GEMNEGCL_02337 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GEMNEGCL_02338 1.91e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GEMNEGCL_02339 2.7e-258 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GEMNEGCL_02340 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GEMNEGCL_02341 9.16e-287 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GEMNEGCL_02342 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GEMNEGCL_02343 5.48e-173 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
GEMNEGCL_02344 2.24e-110 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GEMNEGCL_02346 3.29e-127 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
GEMNEGCL_02347 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GEMNEGCL_02348 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GEMNEGCL_02349 6.25e-268 camS - - S - - - sex pheromone
GEMNEGCL_02350 5.42e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GEMNEGCL_02351 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GEMNEGCL_02352 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GEMNEGCL_02353 3.93e-219 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
GEMNEGCL_02355 1.47e-82 - - - K - - - transcriptional regulator
GEMNEGCL_02356 4.83e-144 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GEMNEGCL_02357 1.64e-65 - - - - - - - -
GEMNEGCL_02358 7.58e-291 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GEMNEGCL_02359 6.85e-255 flp - - V - - - Beta-lactamase
GEMNEGCL_02360 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GEMNEGCL_02361 1.42e-122 - - - K - - - Acetyltransferase (GNAT) domain
GEMNEGCL_02366 0.0 qacA - - EGP - - - Major Facilitator
GEMNEGCL_02367 1.46e-117 - - - K - - - Bacterial regulatory proteins, tetR family
GEMNEGCL_02368 2.93e-223 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GEMNEGCL_02369 2.5e-203 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GEMNEGCL_02370 1.58e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GEMNEGCL_02371 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GEMNEGCL_02372 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GEMNEGCL_02373 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GEMNEGCL_02374 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GEMNEGCL_02375 3.47e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GEMNEGCL_02376 2.04e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GEMNEGCL_02377 9.05e-231 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GEMNEGCL_02378 1.68e-121 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GEMNEGCL_02379 1.52e-212 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GEMNEGCL_02380 6.35e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GEMNEGCL_02381 5.5e-154 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GEMNEGCL_02382 4.37e-132 - - - GM - - - NmrA-like family
GEMNEGCL_02383 1.43e-19 - - - K - - - FCD
GEMNEGCL_02384 1.45e-34 - - - K - - - FCD
GEMNEGCL_02385 6.55e-76 eriC - - P ko:K03281 - ko00000 chloride
GEMNEGCL_02386 6.08e-148 eriC - - P ko:K03281 - ko00000 chloride
GEMNEGCL_02387 1.4e-127 - - - L - - - PFAM Integrase catalytic
GEMNEGCL_02388 3.52e-71 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_02389 4.52e-196 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_02390 9e-132 - - - L - - - Integrase
GEMNEGCL_02391 2.72e-89 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
GEMNEGCL_02392 5.32e-42 - - - - ko:K18829 - ko00000,ko02048 -
GEMNEGCL_02393 1.24e-258 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
GEMNEGCL_02394 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GEMNEGCL_02395 1.28e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GEMNEGCL_02396 8.73e-187 - - - S - - - haloacid dehalogenase-like hydrolase
GEMNEGCL_02397 9.01e-287 - - - S ko:K07133 - ko00000 cog cog1373
GEMNEGCL_02398 3.87e-80 yneE - - K - - - Transcriptional regulator
GEMNEGCL_02399 2.18e-122 yneE - - K - - - Transcriptional regulator
GEMNEGCL_02400 3.58e-61 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
GEMNEGCL_02401 5.05e-11 - - - - - - - -
GEMNEGCL_02402 3.69e-54 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
GEMNEGCL_02403 2.29e-162 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GEMNEGCL_02404 8.06e-110 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GEMNEGCL_02405 3.31e-154 - - - K - - - helix_turn_helix, mercury resistance
GEMNEGCL_02406 3.3e-72 - - - - - - - -
GEMNEGCL_02407 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
GEMNEGCL_02408 5.41e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEMNEGCL_02409 2.1e-31 - - - - - - - -
GEMNEGCL_02410 1.69e-06 - - - - - - - -
GEMNEGCL_02411 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GEMNEGCL_02412 3.25e-231 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GEMNEGCL_02413 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GEMNEGCL_02414 8.03e-160 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GEMNEGCL_02415 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_02416 1.21e-19 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_02417 5.76e-144 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_02418 2.26e-148 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GEMNEGCL_02420 1.29e-41 - - - O - - - OsmC-like protein
GEMNEGCL_02421 1.18e-78 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GEMNEGCL_02423 3.98e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GEMNEGCL_02424 2.29e-274 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
GEMNEGCL_02425 9.66e-12 - - - - - - - -
GEMNEGCL_02426 1.95e-33 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GEMNEGCL_02429 1.72e-97 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GEMNEGCL_02430 1.64e-101 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GEMNEGCL_02431 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GEMNEGCL_02432 6.21e-60 - - - V ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
GEMNEGCL_02436 1.71e-172 - - - S ko:K07052 - ko00000 CAAX amino terminal protease
GEMNEGCL_02437 8.61e-54 - - - S - - - Enterocin A Immunity
GEMNEGCL_02438 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
GEMNEGCL_02439 5.68e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GEMNEGCL_02440 5.61e-72 - - - S - - - pyridoxamine 5-phosphate
GEMNEGCL_02441 1.85e-164 yobV3 - - K - - - WYL domain
GEMNEGCL_02442 2.6e-110 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
GEMNEGCL_02443 1.45e-102 dpsB - - P - - - Belongs to the Dps family
GEMNEGCL_02444 4.22e-41 - - - C - - - Heavy-metal-associated domain
GEMNEGCL_02445 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
GEMNEGCL_02446 6.34e-40 - - - S - - - Pyridoxamine 5'-phosphate oxidase
GEMNEGCL_02447 1.03e-34 - - - S - - - Pyridoxamine 5'-phosphate oxidase
GEMNEGCL_02448 1.77e-220 - - - S - - - Conserved hypothetical protein 698
GEMNEGCL_02450 5e-227 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GEMNEGCL_02451 1.31e-128 - - - I - - - PAP2 superfamily
GEMNEGCL_02452 1.14e-192 - - - S - - - Uncharacterised protein, DegV family COG1307
GEMNEGCL_02453 3.52e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GEMNEGCL_02454 2.32e-127 - - - S - - - Domain of unknown function (DUF4767)
GEMNEGCL_02455 3.47e-49 yfhC - - C - - - nitroreductase
GEMNEGCL_02456 8.12e-48 yfhC - - C - - - nitroreductase
GEMNEGCL_02457 1.22e-174 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
GEMNEGCL_02458 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GEMNEGCL_02459 1.8e-284 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GEMNEGCL_02460 9.5e-153 - - - K ko:K03492 - ko00000,ko03000 UTRA
GEMNEGCL_02461 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GEMNEGCL_02462 4.04e-94 - - - S - - - Domain of unknown function (DUF3284)
GEMNEGCL_02463 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GEMNEGCL_02464 2.92e-79 - - - - - - - -
GEMNEGCL_02465 2.16e-240 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GEMNEGCL_02466 7.5e-194 - - - L - - - An automated process has identified a potential problem with this gene model

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)