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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MELMHNEA_00001	4.76e-140	-	-	-	-	-	-	-	-
MELMHNEA_00002	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
MELMHNEA_00003	2.26e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MELMHNEA_00004	1.33e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MELMHNEA_00005	1.4e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MELMHNEA_00006	3.51e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MELMHNEA_00007	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
MELMHNEA_00008	5.62e-187	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MELMHNEA_00009	1.64e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
MELMHNEA_00010	8.72e-258	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MELMHNEA_00011	1.39e-23	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MELMHNEA_00012	2.55e-300	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MELMHNEA_00013	7.24e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MELMHNEA_00014	1.83e-230	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
MELMHNEA_00015	5.96e-202	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MELMHNEA_00016	2.23e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MELMHNEA_00017	2.94e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MELMHNEA_00018	6.09e-121	-	-	-	-	-	-	-	-
MELMHNEA_00020	7.04e-159	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
MELMHNEA_00021	2.07e-203	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MELMHNEA_00022	1.55e-201	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MELMHNEA_00023	1.49e-178	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
MELMHNEA_00024	2.22e-60	hupB2	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MELMHNEA_00025	2.74e-69	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MELMHNEA_00026	9.43e-52	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MELMHNEA_00027	7.04e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
MELMHNEA_00028	0.0	-	-	-	S	-	-	-	membrane
MELMHNEA_00029	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MELMHNEA_00030	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MELMHNEA_00031	7.92e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MELMHNEA_00032	3.25e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MELMHNEA_00033	1e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MELMHNEA_00034	4.95e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MELMHNEA_00035	3.84e-216	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MELMHNEA_00036	2.05e-286	ynbB	-	-	P	-	-	-	aluminum resistance
MELMHNEA_00037	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MELMHNEA_00038	2.37e-219	-	-	-	-	-	-	-	-
MELMHNEA_00039	2.09e-205	-	-	-	-	-	-	-	-
MELMHNEA_00043	6.78e-47	-	-	-	-	-	-	-	-
MELMHNEA_00044	1.44e-161	-	-	-	S	-	-	-	interspecies interaction between organisms
MELMHNEA_00045	1.28e-09	-	-	-	S	-	-	-	PFAM HicB family
MELMHNEA_00046	2.86e-13	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
MELMHNEA_00047	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MELMHNEA_00048	1.57e-84	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MELMHNEA_00049	2.65e-154	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MELMHNEA_00050	1.03e-112	nanK	-	-	GK	-	-	-	ROK family
MELMHNEA_00051	3.74e-70	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MELMHNEA_00052	6.95e-165	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MELMHNEA_00053	6.48e-279	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MELMHNEA_00054	2.82e-84	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MELMHNEA_00055	1.48e-28	axe1	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	acetyl xylan esterase
MELMHNEA_00056	1.19e-141	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MELMHNEA_00057	1.1e-155	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MELMHNEA_00058	3.07e-136	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MELMHNEA_00059	7.93e-139	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MELMHNEA_00060	2.85e-97	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MELMHNEA_00061	2.21e-63	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MELMHNEA_00062	0.0	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
MELMHNEA_00063	1.48e-139	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
MELMHNEA_00064	4.36e-145	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MELMHNEA_00067	1.24e-159	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MELMHNEA_00068	5.12e-158	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MELMHNEA_00070	1.34e-169	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MELMHNEA_00072	1.95e-75	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
MELMHNEA_00077	1.05e-12	-	-	-	L	-	-	-	DNA primase activity
MELMHNEA_00080	1.74e-99	-	-	-	-	-	-	-	-
MELMHNEA_00081	9.03e-280	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
MELMHNEA_00082	2.42e-108	-	-	-	-	-	-	-	-
MELMHNEA_00088	4.9e-55	-	-	-	L	-	-	-	Probable transposase
MELMHNEA_00089	1.18e-126	-	-	-	L	-	-	-	Probable transposase
MELMHNEA_00090	2.04e-292	-	-	-	E	ko:K03294	-	ko00000	amino acid
MELMHNEA_00091	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MELMHNEA_00092	1.24e-75	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MELMHNEA_00093	1.48e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MELMHNEA_00094	7.92e-218	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MELMHNEA_00095	3.11e-124	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MELMHNEA_00096	1.36e-96	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MELMHNEA_00097	7.09e-184	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_00098	6.89e-136	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MELMHNEA_00099	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MELMHNEA_00100	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MELMHNEA_00101	1.02e-148	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MELMHNEA_00102	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
MELMHNEA_00103	1.87e-308	-	-	-	S	-	-	-	response to antibiotic
MELMHNEA_00104	2.7e-162	-	-	-	-	-	-	-	-
MELMHNEA_00105	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MELMHNEA_00106	7.34e-86	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MELMHNEA_00107	1.42e-57	-	-	-	-	-	-	-	-
MELMHNEA_00108	4.65e-14	-	-	-	-	-	-	-	-
MELMHNEA_00109	5.32e-42	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
MELMHNEA_00110	1.64e-90	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
MELMHNEA_00111	9e-132	-	-	-	L	-	-	-	Integrase
MELMHNEA_00112	4.52e-196	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MELMHNEA_00113	3.52e-71	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MELMHNEA_00114	7.07e-126	-	-	-	L	-	-	-	PFAM Integrase catalytic
MELMHNEA_00115	2.84e-146	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MELMHNEA_00116	6.55e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MELMHNEA_00117	1.45e-34	-	-	-	K	-	-	-	FCD
MELMHNEA_00118	1.43e-19	-	-	-	K	-	-	-	FCD
MELMHNEA_00119	4.37e-132	-	-	-	GM	-	-	-	NmrA-like family
MELMHNEA_00120	5.5e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MELMHNEA_00121	6.35e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MELMHNEA_00122	1.52e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MELMHNEA_00123	1.01e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MELMHNEA_00124	9.05e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MELMHNEA_00125	2.04e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MELMHNEA_00126	3.47e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MELMHNEA_00127	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MELMHNEA_00128	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MELMHNEA_00129	2.37e-190	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MELMHNEA_00130	1.45e-60	-	-	-	-	-	-	-	-
MELMHNEA_00131	2.88e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MELMHNEA_00132	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MELMHNEA_00133	2.19e-49	-	-	-	S	-	-	-	Alpha beta hydrolase
MELMHNEA_00134	2.1e-82	-	-	-	S	-	-	-	Alpha beta hydrolase
MELMHNEA_00135	8.51e-50	-	-	-	-	-	-	-	-
MELMHNEA_00136	6.51e-51	-	-	-	-	-	-	-	-
MELMHNEA_00137	6.92e-145	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MELMHNEA_00138	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MELMHNEA_00139	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MELMHNEA_00140	1.82e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MELMHNEA_00141	3.02e-228	lipA	-	-	I	-	-	-	Carboxylesterase family
MELMHNEA_00143	5.27e-266	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MELMHNEA_00144	2.99e-202	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
MELMHNEA_00145	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MELMHNEA_00146	2.07e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MELMHNEA_00149	3.7e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
MELMHNEA_00150	5.14e-105	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MELMHNEA_00151	2.45e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MELMHNEA_00152	1.4e-208	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MELMHNEA_00153	1.6e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MELMHNEA_00154	8.62e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MELMHNEA_00155	3.65e-273	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MELMHNEA_00156	7.15e-277	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MELMHNEA_00157	2.6e-59	-	-	-	-	-	-	-	-
MELMHNEA_00158	1.52e-34	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MELMHNEA_00159	1.17e-151	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MELMHNEA_00160	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MELMHNEA_00161	3.39e-186	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MELMHNEA_00162	1.43e-110	-	-	-	-	-	-	-	-
MELMHNEA_00163	3.85e-98	-	-	-	-	-	-	-	-
MELMHNEA_00164	1.51e-182	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MELMHNEA_00165	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MELMHNEA_00166	8.42e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
MELMHNEA_00167	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MELMHNEA_00168	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MELMHNEA_00169	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MELMHNEA_00170	6.28e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MELMHNEA_00171	1.5e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MELMHNEA_00172	7.37e-158	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MELMHNEA_00173	3.83e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MELMHNEA_00174	5.74e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
MELMHNEA_00175	1.71e-143	-	-	-	S	-	-	-	CYTH
MELMHNEA_00176	1.7e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MELMHNEA_00177	1.91e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MELMHNEA_00178	7.96e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MELMHNEA_00179	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MELMHNEA_00180	3.77e-122	-	-	-	S	-	-	-	SNARE associated Golgi protein
MELMHNEA_00181	6.73e-51	-	-	-	-	-	-	-	-
MELMHNEA_00182	7.51e-145	-	-	-	K	-	-	-	WHG domain
MELMHNEA_00183	3.41e-125	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MELMHNEA_00184	2.12e-125	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MELMHNEA_00185	9.48e-194	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MELMHNEA_00186	6.11e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MELMHNEA_00188	2.99e-75	cvpA	-	-	S	-	-	-	Colicin V production protein
MELMHNEA_00189	3.66e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MELMHNEA_00190	5.86e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MELMHNEA_00191	4.99e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MELMHNEA_00192	4.28e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MELMHNEA_00193	4.49e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MELMHNEA_00194	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MELMHNEA_00195	3.93e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MELMHNEA_00196	1.22e-190	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00197	1.68e-179	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00198	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MELMHNEA_00199	8.32e-157	vanR	-	-	K	-	-	-	response regulator
MELMHNEA_00200	9.28e-271	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MELMHNEA_00201	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MELMHNEA_00202	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MELMHNEA_00203	6.94e-70	-	-	-	S	-	-	-	Enterocin A Immunity
MELMHNEA_00204	1.95e-45	-	-	-	-	-	-	-	-
MELMHNEA_00205	1.07e-35	-	-	-	-	-	-	-	-
MELMHNEA_00206	4.48e-34	-	-	-	-	-	-	-	-
MELMHNEA_00207	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MELMHNEA_00208	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
MELMHNEA_00209	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MELMHNEA_00210	1.89e-23	-	-	-	-	-	-	-	-
MELMHNEA_00211	7.34e-178	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MELMHNEA_00212	2.08e-164	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MELMHNEA_00213	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MELMHNEA_00214	7.86e-138	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
MELMHNEA_00215	5.02e-180	blpT	-	-	-	-	-	-	-
MELMHNEA_00219	7.87e-30	-	-	-	-	-	-	-	-
MELMHNEA_00220	4.74e-107	-	-	-	-	-	-	-	-
MELMHNEA_00221	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MELMHNEA_00222	2.52e-32	-	-	-	-	-	-	-	-
MELMHNEA_00223	3.41e-88	-	-	-	-	-	-	-	-
MELMHNEA_00224	3.09e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00225	6.39e-279	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MELMHNEA_00226	3.14e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MELMHNEA_00227	2.18e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MELMHNEA_00228	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
MELMHNEA_00229	4.47e-56	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MELMHNEA_00230	2.96e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MELMHNEA_00231	1.63e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MELMHNEA_00232	1.59e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MELMHNEA_00233	3.43e-192	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MELMHNEA_00234	2.89e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00235	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MELMHNEA_00236	1.41e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MELMHNEA_00237	7.63e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MELMHNEA_00238	1.14e-164	terC	-	-	P	-	-	-	Integral membrane protein TerC family
MELMHNEA_00239	1.25e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
MELMHNEA_00240	3.45e-144	-	-	-	L	-	-	-	Resolvase, N-terminal
MELMHNEA_00241	3.14e-260	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MELMHNEA_00242	1.58e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MELMHNEA_00243	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MELMHNEA_00244	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MELMHNEA_00245	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MELMHNEA_00246	2.65e-224	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MELMHNEA_00247	7.42e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MELMHNEA_00248	1.72e-286	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
MELMHNEA_00255	1.29e-164	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_00256	4.34e-64	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MELMHNEA_00257	2.04e-60	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
MELMHNEA_00258	2.15e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
MELMHNEA_00259	2.89e-312	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
MELMHNEA_00260	3.02e-187	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MELMHNEA_00261	4.63e-92	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MELMHNEA_00262	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MELMHNEA_00263	1.76e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MELMHNEA_00264	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
MELMHNEA_00265	1.8e-34	-	-	-	-	-	-	-	-
MELMHNEA_00266	3.55e-182	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MELMHNEA_00267	6.74e-214	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
MELMHNEA_00268	2.55e-94	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MELMHNEA_00269	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MELMHNEA_00270	2.9e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MELMHNEA_00271	3.72e-202	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_00272	4.57e-163	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00273	1.68e-149	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MELMHNEA_00274	5.18e-139	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MELMHNEA_00276	3.71e-76	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MELMHNEA_00277	1.37e-173	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MELMHNEA_00278	1.32e-57	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MELMHNEA_00279	2.43e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MELMHNEA_00280	3.23e-108	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MELMHNEA_00281	2.95e-283	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_00282	4.28e-125	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MELMHNEA_00283	2.19e-18	-	-	-	-	-	-	-	-
MELMHNEA_00284	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MELMHNEA_00285	3.52e-163	csrR	-	-	K	-	-	-	response regulator
MELMHNEA_00286	2.14e-234	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MELMHNEA_00287	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MELMHNEA_00288	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MELMHNEA_00289	2.14e-231	-	-	-	M	-	-	-	CHAP domain
MELMHNEA_00290	7.99e-102	-	-	-	-	-	-	-	-
MELMHNEA_00291	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MELMHNEA_00292	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MELMHNEA_00293	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MELMHNEA_00294	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MELMHNEA_00295	3.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MELMHNEA_00296	1.39e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MELMHNEA_00297	7.58e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MELMHNEA_00298	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MELMHNEA_00299	4.29e-275	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MELMHNEA_00300	3.16e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MELMHNEA_00301	1.32e-305	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MELMHNEA_00302	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MELMHNEA_00303	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MELMHNEA_00304	9.37e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MELMHNEA_00305	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MELMHNEA_00306	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MELMHNEA_00307	5.37e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MELMHNEA_00308	2.34e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MELMHNEA_00309	9.73e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MELMHNEA_00310	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MELMHNEA_00311	9.6e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MELMHNEA_00312	9.94e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MELMHNEA_00313	2.12e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MELMHNEA_00314	2.88e-106	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MELMHNEA_00315	1.16e-243	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MELMHNEA_00316	2.7e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MELMHNEA_00317	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MELMHNEA_00318	2.57e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MELMHNEA_00319	6.28e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MELMHNEA_00320	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MELMHNEA_00321	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MELMHNEA_00322	5.43e-191	-	-	-	-	-	-	-	-
MELMHNEA_00323	5.76e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MELMHNEA_00324	1.09e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MELMHNEA_00325	3.04e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MELMHNEA_00326	1.59e-136	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MELMHNEA_00327	2.58e-48	potE	-	-	E	-	-	-	Amino Acid
MELMHNEA_00328	1.27e-220	potE	-	-	E	-	-	-	Amino Acid
MELMHNEA_00329	6.25e-246	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MELMHNEA_00330	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MELMHNEA_00331	1.39e-312	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MELMHNEA_00332	8.62e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MELMHNEA_00333	8.08e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MELMHNEA_00334	3.66e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MELMHNEA_00335	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MELMHNEA_00336	7.42e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MELMHNEA_00337	1.05e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MELMHNEA_00338	4.2e-249	pbpX1	-	-	V	-	-	-	Beta-lactamase
MELMHNEA_00339	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MELMHNEA_00340	3.04e-53	-	-	-	C	-	-	-	FMN_bind
MELMHNEA_00341	3.85e-109	-	-	-	-	-	-	-	-
MELMHNEA_00342	7.39e-225	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
MELMHNEA_00343	2.49e-117	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
MELMHNEA_00344	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MELMHNEA_00345	1.33e-165	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
MELMHNEA_00346	1.32e-74	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MELMHNEA_00347	4.56e-78	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
MELMHNEA_00348	2.72e-15	-	-	-	-	-	-	-	-
MELMHNEA_00349	6.41e-138	-	-	-	L	-	-	-	Probable transposase
MELMHNEA_00350	1.85e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MELMHNEA_00351	1.38e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MELMHNEA_00352	6.77e-49	-	-	-	-	-	-	-	-
MELMHNEA_00353	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MELMHNEA_00354	1.8e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MELMHNEA_00355	2.03e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MELMHNEA_00356	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MELMHNEA_00357	9.14e-283	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MELMHNEA_00359	3.82e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MELMHNEA_00360	1.19e-43	-	-	-	S	-	-	-	reductase
MELMHNEA_00361	2.98e-50	-	-	-	S	-	-	-	reductase
MELMHNEA_00362	6.32e-41	-	-	-	S	-	-	-	reductase
MELMHNEA_00363	2.13e-189	yxeH	-	-	S	-	-	-	hydrolase
MELMHNEA_00364	1.14e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MELMHNEA_00365	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MELMHNEA_00366	1.58e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MELMHNEA_00367	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MELMHNEA_00368	1.88e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MELMHNEA_00369	0.0	oatA	-	-	I	-	-	-	Acyltransferase
MELMHNEA_00370	6.82e-223	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MELMHNEA_00371	6.84e-183	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MELMHNEA_00372	3.57e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MELMHNEA_00373	5.14e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MELMHNEA_00374	6.34e-166	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MELMHNEA_00377	1.29e-32	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
MELMHNEA_00379	1.8e-20	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_00382	1.7e-23	-	-	-	-	-	-	-	-
MELMHNEA_00383	2.87e-93	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
MELMHNEA_00390	8.93e-33	-	-	-	S	-	-	-	HNH endonuclease
MELMHNEA_00391	9.54e-88	-	-	-	S	-	-	-	AAA domain
MELMHNEA_00393	8.94e-192	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MELMHNEA_00396	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
MELMHNEA_00408	2.71e-49	-	-	-	S	-	-	-	VRR_NUC
MELMHNEA_00412	1.71e-72	-	-	-	S	-	-	-	Phage terminase, small subunit
MELMHNEA_00414	2.37e-263	-	-	-	S	-	-	-	Phage Terminase
MELMHNEA_00416	4.25e-167	-	-	-	S	-	-	-	Phage portal protein
MELMHNEA_00417	1.59e-110	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MELMHNEA_00418	8.25e-69	-	-	-	S	-	-	-	Phage capsid family
MELMHNEA_00426	1.13e-132	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MELMHNEA_00428	7.82e-158	-	-	-	S	-	-	-	Phage minor structural protein
MELMHNEA_00437	5.77e-39	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MELMHNEA_00438	5.45e-106	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
MELMHNEA_00440	4.79e-15	-	-	-	-	-	-	-	-
MELMHNEA_00441	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MELMHNEA_00442	1.03e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MELMHNEA_00443	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MELMHNEA_00444	5.46e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MELMHNEA_00445	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MELMHNEA_00446	1.21e-213	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MELMHNEA_00447	6.74e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MELMHNEA_00448	7.97e-82	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MELMHNEA_00449	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MELMHNEA_00450	7.57e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MELMHNEA_00451	4.65e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MELMHNEA_00452	2.32e-47	-	-	-	-	-	-	-	-
MELMHNEA_00453	1.76e-233	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MELMHNEA_00454	8.37e-161	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MELMHNEA_00455	1.11e-177	-	-	-	-	-	-	-	-
MELMHNEA_00456	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MELMHNEA_00457	1.01e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00458	7.36e-291	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MELMHNEA_00459	2.43e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MELMHNEA_00460	2.45e-164	-	-	-	-	-	-	-	-
MELMHNEA_00461	1.69e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MELMHNEA_00462	2.23e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MELMHNEA_00463	1.2e-202	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MELMHNEA_00464	3.57e-170	-	-	-	L	-	-	-	Phage integrase family
MELMHNEA_00465	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MELMHNEA_00466	3.22e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MELMHNEA_00467	1.06e-185	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MELMHNEA_00468	5.12e-174	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MELMHNEA_00469	5.5e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MELMHNEA_00470	2.41e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MELMHNEA_00471	2.23e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MELMHNEA_00472	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MELMHNEA_00473	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MELMHNEA_00474	3.44e-72	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MELMHNEA_00475	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MELMHNEA_00476	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MELMHNEA_00477	3.7e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MELMHNEA_00478	1.25e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MELMHNEA_00479	4.95e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MELMHNEA_00480	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MELMHNEA_00481	3.73e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MELMHNEA_00482	2.8e-72	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MELMHNEA_00483	7.18e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MELMHNEA_00484	7.94e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MELMHNEA_00485	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MELMHNEA_00486	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MELMHNEA_00487	3.03e-44	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MELMHNEA_00488	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MELMHNEA_00489	1.56e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MELMHNEA_00490	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MELMHNEA_00491	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MELMHNEA_00492	8.7e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MELMHNEA_00493	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MELMHNEA_00494	1.14e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MELMHNEA_00495	4.01e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MELMHNEA_00496	1.14e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MELMHNEA_00497	4.68e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MELMHNEA_00498	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MELMHNEA_00499	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MELMHNEA_00500	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MELMHNEA_00501	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MELMHNEA_00502	1.47e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MELMHNEA_00503	7.71e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
MELMHNEA_00504	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MELMHNEA_00505	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MELMHNEA_00506	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MELMHNEA_00507	1.92e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MELMHNEA_00509	4.91e-243	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MELMHNEA_00510	2.91e-103	-	-	-	S	-	-	-	Phage portal protein
MELMHNEA_00511	2.67e-95	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MELMHNEA_00512	7.4e-57	-	-	-	S	-	-	-	Phage capsid family
MELMHNEA_00513	1.2e-23	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MELMHNEA_00515	1.42e-23	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MELMHNEA_00520	9.77e-175	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MELMHNEA_00521	3.54e-36	-	-	-	S	-	-	-	phage tail
MELMHNEA_00523	1.41e-126	-	-	-	S	-	-	-	Phage minor structural protein
MELMHNEA_00530	7.99e-87	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MELMHNEA_00531	3.01e-137	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MELMHNEA_00532	1.71e-150	-	-	-	S	-	-	-	Peptidase family M23
MELMHNEA_00533	1.25e-17	-	-	-	-	-	-	-	-
MELMHNEA_00534	1.61e-219	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MELMHNEA_00535	1.04e-41	-	-	-	-	-	-	-	-
MELMHNEA_00537	3.65e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MELMHNEA_00538	6.24e-145	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MELMHNEA_00539	4.51e-77	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MELMHNEA_00541	5.34e-55	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MELMHNEA_00542	2.97e-111	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MELMHNEA_00543	1.49e-290	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MELMHNEA_00544	7.82e-80	-	-	-	-	-	-	-	-
MELMHNEA_00545	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MELMHNEA_00546	4.13e-310	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
MELMHNEA_00547	0.0	-	-	-	S	-	-	-	TerB-C domain
MELMHNEA_00548	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MELMHNEA_00549	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MELMHNEA_00550	6.94e-202	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_00551	9.05e-78	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
MELMHNEA_00552	3.36e-42	-	-	-	-	-	-	-	-
MELMHNEA_00553	2.53e-100	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MELMHNEA_00554	5.26e-36	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MELMHNEA_00555	2.7e-277	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
MELMHNEA_00556	5.75e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MELMHNEA_00557	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MELMHNEA_00558	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
MELMHNEA_00559	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MELMHNEA_00560	4.85e-228	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MELMHNEA_00561	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MELMHNEA_00562	1.61e-308	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MELMHNEA_00563	7.06e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MELMHNEA_00564	2.07e-203	-	-	-	K	-	-	-	Transcriptional regulator
MELMHNEA_00565	1.31e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
MELMHNEA_00566	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MELMHNEA_00567	9.65e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MELMHNEA_00568	2.72e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MELMHNEA_00569	6.41e-194	-	-	-	-	-	-	-	-
MELMHNEA_00570	7.64e-307	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MELMHNEA_00571	3.41e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MELMHNEA_00572	6.43e-167	-	-	-	F	-	-	-	glutamine amidotransferase
MELMHNEA_00573	2.05e-188	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MELMHNEA_00574	2.53e-106	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MELMHNEA_00575	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00576	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
MELMHNEA_00577	7.3e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MELMHNEA_00578	1.34e-106	-	-	-	G	-	-	-	MFS/sugar transport protein
MELMHNEA_00579	6.3e-191	-	-	-	G	-	-	-	MFS/sugar transport protein
MELMHNEA_00580	6.42e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
MELMHNEA_00581	1.19e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00582	1.5e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_00583	7.42e-123	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MELMHNEA_00584	8.58e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MELMHNEA_00585	1.04e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
MELMHNEA_00586	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MELMHNEA_00587	2.77e-248	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MELMHNEA_00588	3.91e-214	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MELMHNEA_00589	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MELMHNEA_00590	3.35e-308	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MELMHNEA_00591	1.61e-81	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
MELMHNEA_00592	7.52e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MELMHNEA_00593	7.32e-46	yabO	-	-	J	-	-	-	S4 domain protein
MELMHNEA_00594	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MELMHNEA_00595	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MELMHNEA_00596	2.93e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MELMHNEA_00597	1.23e-166	-	-	-	S	-	-	-	(CBS) domain
MELMHNEA_00598	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MELMHNEA_00599	9.39e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MELMHNEA_00600	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MELMHNEA_00601	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MELMHNEA_00602	1.07e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MELMHNEA_00603	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
MELMHNEA_00604	1.64e-200	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MELMHNEA_00605	0.0	-	-	-	E	-	-	-	amino acid
MELMHNEA_00606	1.33e-295	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MELMHNEA_00607	1.17e-56	-	-	-	-	-	-	-	-
MELMHNEA_00608	8.68e-69	-	-	-	-	-	-	-	-
MELMHNEA_00609	3.44e-238	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
MELMHNEA_00610	8.88e-178	-	-	-	P	-	-	-	Voltage gated chloride channel
MELMHNEA_00611	6.6e-219	-	-	-	L	-	-	-	Bifunctional protein
MELMHNEA_00612	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
MELMHNEA_00613	1.03e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MELMHNEA_00614	9.78e-257	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MELMHNEA_00615	5.18e-128	-	-	-	G	-	-	-	Aldose 1-epimerase
MELMHNEA_00616	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MELMHNEA_00617	1.72e-149	-	-	-	-	-	-	-	-
MELMHNEA_00618	1.98e-168	-	-	-	-	-	-	-	-
MELMHNEA_00619	3.95e-206	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MELMHNEA_00620	2.47e-138	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MELMHNEA_00621	7.07e-141	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MELMHNEA_00622	1.64e-222	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MELMHNEA_00623	7.32e-232	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
MELMHNEA_00624	2.09e-286	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MELMHNEA_00628	1.24e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MELMHNEA_00629	1.27e-311	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MELMHNEA_00630	8.12e-60	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MELMHNEA_00631	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MELMHNEA_00632	6.98e-78	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MELMHNEA_00633	1.39e-224	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MELMHNEA_00634	6.22e-232	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MELMHNEA_00635	4.43e-179	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MELMHNEA_00636	1.51e-154	-	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
MELMHNEA_00637	1.24e-188	-	5.2.1.13	-	Q	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
MELMHNEA_00638	7.13e-67	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
MELMHNEA_00639	5.71e-230	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MELMHNEA_00640	2.36e-213	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MELMHNEA_00641	2.24e-71	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MELMHNEA_00642	1.06e-58	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MELMHNEA_00643	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MELMHNEA_00644	7.02e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MELMHNEA_00645	6.6e-237	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MELMHNEA_00646	1.24e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MELMHNEA_00647	1.66e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MELMHNEA_00648	5.28e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MELMHNEA_00649	5.87e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MELMHNEA_00650	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MELMHNEA_00651	2.48e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MELMHNEA_00652	5.38e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MELMHNEA_00653	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MELMHNEA_00654	1.48e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MELMHNEA_00655	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MELMHNEA_00656	2.45e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MELMHNEA_00657	2.54e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MELMHNEA_00658	4.81e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MELMHNEA_00659	1.59e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MELMHNEA_00660	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MELMHNEA_00661	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MELMHNEA_00662	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
MELMHNEA_00663	1.35e-56	-	-	-	-	-	-	-	-
MELMHNEA_00664	1.47e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MELMHNEA_00665	8.08e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MELMHNEA_00666	3.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MELMHNEA_00667	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MELMHNEA_00668	8.32e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MELMHNEA_00669	2.45e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MELMHNEA_00670	4.6e-158	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MELMHNEA_00671	5.87e-110	-	-	-	-	-	-	-	-
MELMHNEA_00672	0.0	-	-	-	-	-	-	-	-
MELMHNEA_00674	9.84e-63	-	-	-	S	-	-	-	Fic/DOC family
MELMHNEA_00675	0.0	potE	-	-	E	-	-	-	Amino Acid
MELMHNEA_00676	6.69e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MELMHNEA_00677	4.78e-308	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MELMHNEA_00678	5.17e-169	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MELMHNEA_00679	2.83e-115	-	-	-	L	-	-	-	Transposase
MELMHNEA_00680	3.32e-207	-	-	-	L	-	-	-	Transposase
MELMHNEA_00681	1.6e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MELMHNEA_00682	1.56e-198	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MELMHNEA_00683	1.63e-159	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MELMHNEA_00684	1.87e-58	-	-	-	-	-	-	-	-
MELMHNEA_00685	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MELMHNEA_00687	8.53e-84	-	-	-	K	-	-	-	LytTr DNA-binding domain
MELMHNEA_00688	6.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MELMHNEA_00689	4.57e-135	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MELMHNEA_00690	1.1e-152	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MELMHNEA_00691	2.02e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MELMHNEA_00692	3.16e-160	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MELMHNEA_00693	8.43e-206	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MELMHNEA_00694	2.42e-33	-	-	-	-	-	-	-	-
MELMHNEA_00695	9.82e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MELMHNEA_00696	2.32e-234	-	-	-	S	-	-	-	AAA domain
MELMHNEA_00697	1.84e-49	-	-	-	-	-	-	-	-
MELMHNEA_00698	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MELMHNEA_00699	4.51e-69	-	-	-	-	-	-	-	-
MELMHNEA_00700	6.45e-291	-	-	-	E	-	-	-	amino acid
MELMHNEA_00701	6.65e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MELMHNEA_00703	1.95e-221	-	-	-	V	-	-	-	HNH endonuclease
MELMHNEA_00704	6.36e-173	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MELMHNEA_00705	5.27e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MELMHNEA_00706	2.58e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MELMHNEA_00707	5.08e-149	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MELMHNEA_00708	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
MELMHNEA_00709	7.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MELMHNEA_00710	3.09e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MELMHNEA_00711	1.68e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00712	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MELMHNEA_00713	1.96e-49	-	-	-	-	-	-	-	-
MELMHNEA_00714	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MELMHNEA_00715	1.34e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MELMHNEA_00716	2.5e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MELMHNEA_00717	5.64e-227	pbpX2	-	-	V	-	-	-	Beta-lactamase
MELMHNEA_00718	6.8e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MELMHNEA_00719	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MELMHNEA_00720	2.95e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MELMHNEA_00721	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MELMHNEA_00722	1.3e-26	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MELMHNEA_00723	1.42e-58	-	-	-	-	-	-	-	-
MELMHNEA_00724	5.11e-265	-	-	-	S	-	-	-	Membrane
MELMHNEA_00725	3.41e-107	ykuL	-	-	S	-	-	-	(CBS) domain
MELMHNEA_00726	0.0	cadA	-	-	P	-	-	-	P-type ATPase
MELMHNEA_00727	5.71e-263	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
MELMHNEA_00728	2.49e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MELMHNEA_00729	1.68e-55	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
MELMHNEA_00730	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MELMHNEA_00731	1.91e-200	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_00732	1.05e-67	-	-	-	-	-	-	-	-
MELMHNEA_00733	3.62e-202	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MELMHNEA_00734	2.86e-139	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MELMHNEA_00735	1.2e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MELMHNEA_00736	5.26e-244	-	-	-	S	-	-	-	DUF218 domain
MELMHNEA_00737	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00738	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MELMHNEA_00739	5.9e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MELMHNEA_00740	9.76e-256	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MELMHNEA_00741	4.57e-232	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MELMHNEA_00742	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MELMHNEA_00743	8.8e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MELMHNEA_00744	3.63e-221	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MELMHNEA_00745	9.99e-89	-	-	-	S	-	-	-	Aldo/keto reductase family
MELMHNEA_00746	4.04e-99	-	-	-	S	-	-	-	Aldo/keto reductase family
MELMHNEA_00747	1.15e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MELMHNEA_00748	9.85e-154	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MELMHNEA_00749	1.06e-159	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MELMHNEA_00750	2.6e-93	-	-	-	-	-	-	-	-
MELMHNEA_00751	4.24e-178	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MELMHNEA_00752	6.82e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MELMHNEA_00753	1.91e-97	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MELMHNEA_00754	4.03e-75	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MELMHNEA_00755	2.53e-117	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00756	1.02e-19	-	-	-	S	-	-	-	Phage portal protein
MELMHNEA_00758	4.69e-271	-	-	-	S	-	-	-	Phage Terminase
MELMHNEA_00761	6.95e-71	-	-	-	L	-	-	-	Phage terminase, small subunit
MELMHNEA_00762	3.73e-80	-	-	-	L	-	-	-	HNH nucleases
MELMHNEA_00763	2.55e-09	-	-	-	-	-	-	-	-
MELMHNEA_00769	1.21e-106	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
MELMHNEA_00775	9.66e-13	-	-	-	-	-	-	-	-
MELMHNEA_00778	5.65e-23	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MELMHNEA_00786	2.86e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_00787	5.53e-95	-	-	-	K	-	-	-	Peptidase S24-like
MELMHNEA_00788	1.25e-24	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
MELMHNEA_00791	8.96e-231	-	-	-	V	-	-	-	Abi-like protein
MELMHNEA_00792	4.87e-154	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MELMHNEA_00793	2.48e-12	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MELMHNEA_00795	2.83e-205	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MELMHNEA_00796	1.34e-151	-	-	-	-	-	-	-	-
MELMHNEA_00797	3.06e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MELMHNEA_00798	2.95e-283	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MELMHNEA_00799	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MELMHNEA_00800	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MELMHNEA_00801	6.83e-133	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
MELMHNEA_00802	0.0	-	-	-	L	-	-	-	PLD-like domain
MELMHNEA_00803	5.97e-55	-	-	-	S	-	-	-	SnoaL-like domain
MELMHNEA_00804	6.13e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
MELMHNEA_00805	8.71e-31	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
MELMHNEA_00806	5.51e-35	-	-	-	-	-	-	-	-
MELMHNEA_00807	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MELMHNEA_00808	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MELMHNEA_00809	1.77e-157	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MELMHNEA_00810	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MELMHNEA_00812	7.03e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MELMHNEA_00813	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
MELMHNEA_00814	1.15e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MELMHNEA_00815	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MELMHNEA_00816	7e-131	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MELMHNEA_00817	9.71e-47	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MELMHNEA_00818	5.3e-32	-	-	-	-	-	-	-	-
MELMHNEA_00819	8.77e-220	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MELMHNEA_00820	2.16e-39	-	-	-	-	-	-	-	-
MELMHNEA_00821	6.31e-27	-	-	-	-	-	-	-	-
MELMHNEA_00824	2.12e-27	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
MELMHNEA_00825	1.01e-54	-	-	-	-	-	-	-	-
MELMHNEA_00829	2.34e-41	-	-	-	-	-	-	-	-
MELMHNEA_00831	3.21e-155	-	-	-	S	-	-	-	Baseplate J-like protein
MELMHNEA_00832	4.78e-43	-	-	-	-	-	-	-	-
MELMHNEA_00833	4.6e-63	-	-	-	-	-	-	-	-
MELMHNEA_00834	1.36e-129	-	-	-	-	-	-	-	-
MELMHNEA_00835	6.91e-61	-	-	-	-	-	-	-	-
MELMHNEA_00836	2.17e-64	-	-	-	M	-	-	-	LysM domain
MELMHNEA_00837	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MELMHNEA_00840	1.33e-73	-	-	-	-	-	-	-	-
MELMHNEA_00841	1.12e-193	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
MELMHNEA_00842	5.61e-69	-	-	-	-	-	-	-	-
MELMHNEA_00843	6e-58	-	-	-	-	-	-	-	-
MELMHNEA_00844	7.63e-97	-	-	-	-	-	-	-	-
MELMHNEA_00846	3.18e-182	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2184)
MELMHNEA_00847	3.08e-76	-	-	-	-	-	-	-	-
MELMHNEA_00848	2.77e-137	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
MELMHNEA_00849	1.14e-16	-	-	-	S	-	-	-	Lysin motif
MELMHNEA_00850	1.38e-125	-	-	-	S	-	-	-	Phage Mu protein F like protein
MELMHNEA_00851	5.29e-177	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
MELMHNEA_00852	5.64e-290	-	-	-	S	-	-	-	Terminase-like family
MELMHNEA_00853	3.6e-47	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
MELMHNEA_00854	7.69e-16	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
MELMHNEA_00855	8.27e-46	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
MELMHNEA_00862	1.08e-10	-	-	-	-	-	-	-	-
MELMHNEA_00863	5.99e-52	-	-	-	L	-	-	-	Endodeoxyribonuclease RusA
MELMHNEA_00869	6.52e-64	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
MELMHNEA_00870	1.4e-39	-	-	-	S	-	-	-	Conserved phage C-terminus (Phg_2220_C)
MELMHNEA_00871	6.82e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
MELMHNEA_00875	3.76e-07	-	-	-	K	-	-	-	Helix-turn-helix domain
MELMHNEA_00881	2.06e-123	-	-	-	S	-	-	-	AntA/AntB antirepressor
MELMHNEA_00882	2.18e-07	-	-	-	-	-	-	-	-
MELMHNEA_00887	8.82e-97	-	-	-	S	-	-	-	Phage antirepressor protein KilAC domain
MELMHNEA_00889	1.74e-17	-	-	-	-	-	-	-	-
MELMHNEA_00890	1.87e-21	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MELMHNEA_00892	2.28e-19	-	-	-	-	-	-	-	-
MELMHNEA_00897	1.09e-226	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MELMHNEA_00898	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MELMHNEA_00899	5.88e-278	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MELMHNEA_00900	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MELMHNEA_00901	3.74e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MELMHNEA_00902	1.11e-76	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MELMHNEA_00903	5.35e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MELMHNEA_00904	1.64e-198	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MELMHNEA_00905	1.67e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MELMHNEA_00906	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MELMHNEA_00907	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
MELMHNEA_00908	3.75e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MELMHNEA_00909	1.19e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MELMHNEA_00910	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MELMHNEA_00911	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MELMHNEA_00912	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MELMHNEA_00913	6.38e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MELMHNEA_00914	3.93e-181	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MELMHNEA_00915	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MELMHNEA_00916	1.22e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MELMHNEA_00917	5.86e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MELMHNEA_00918	1.76e-235	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MELMHNEA_00919	2.21e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MELMHNEA_00920	2.03e-251	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MELMHNEA_00921	2.74e-150	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MELMHNEA_00922	4.94e-292	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MELMHNEA_00923	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MELMHNEA_00924	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MELMHNEA_00925	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MELMHNEA_00926	1.3e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MELMHNEA_00927	4.16e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
MELMHNEA_00928	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MELMHNEA_00930	1.01e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MELMHNEA_00931	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MELMHNEA_00932	2.19e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
MELMHNEA_00933	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MELMHNEA_00934	3.12e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
MELMHNEA_00935	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MELMHNEA_00936	1.47e-284	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MELMHNEA_00937	5.49e-301	ymfH	-	-	S	-	-	-	Peptidase M16
MELMHNEA_00938	1.39e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MELMHNEA_00939	2.13e-152	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
MELMHNEA_00940	3.92e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MELMHNEA_00941	1.17e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MELMHNEA_00942	3.03e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MELMHNEA_00943	1.94e-268	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
MELMHNEA_00944	5.04e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MELMHNEA_00945	2.68e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MELMHNEA_00946	9.44e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MELMHNEA_00947	1.55e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MELMHNEA_00948	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MELMHNEA_00949	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MELMHNEA_00950	8.33e-27	-	-	-	-	-	-	-	-
MELMHNEA_00951	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MELMHNEA_00952	4.04e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MELMHNEA_00953	3.31e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MELMHNEA_00954	3.42e-232	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MELMHNEA_00955	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MELMHNEA_00956	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MELMHNEA_00957	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MELMHNEA_00958	1.55e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MELMHNEA_00959	2.44e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MELMHNEA_00960	2.78e-251	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MELMHNEA_00961	8.59e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MELMHNEA_00962	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MELMHNEA_00965	4.06e-132	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MELMHNEA_00966	8.32e-171	-	-	-	-	-	-	-	-
MELMHNEA_00967	3.18e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MELMHNEA_00968	7.4e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MELMHNEA_00969	2.96e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MELMHNEA_00970	3.09e-71	-	-	-	-	-	-	-	-
MELMHNEA_00971	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MELMHNEA_00972	2.12e-132	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_00973	4.28e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MELMHNEA_00974	1.98e-117	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MELMHNEA_00975	2.75e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
MELMHNEA_00976	3.29e-109	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MELMHNEA_00977	2.65e-89	-	-	-	O	-	-	-	OsmC-like protein
MELMHNEA_00978	5.3e-264	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MELMHNEA_00979	3e-290	sptS	-	-	T	-	-	-	Histidine kinase
MELMHNEA_00980	2.14e-85	dltr	-	-	K	-	-	-	response regulator
MELMHNEA_00981	4.52e-35	dltr	-	-	K	-	-	-	response regulator
MELMHNEA_00982	6.17e-140	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
MELMHNEA_00983	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
MELMHNEA_00984	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MELMHNEA_00985	1.72e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MELMHNEA_00986	1.02e-195	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MELMHNEA_00987	8.41e-202	msmF	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MELMHNEA_00988	3.19e-302	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MELMHNEA_00989	3.13e-206	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MELMHNEA_00990	2.14e-48	-	-	-	-	-	-	-	-
MELMHNEA_00991	8.29e-254	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MELMHNEA_00992	3.97e-125	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MELMHNEA_00993	1.28e-168	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
MELMHNEA_00994	5.34e-143	crt	4.2.1.17	-	I	ko:K01715	ko00650,ko01200,map00650,map01200	ko00000,ko00001,ko01000	Enoyl-CoA hydratase/isomerase
MELMHNEA_00995	1.02e-192	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
MELMHNEA_00996	8.45e-102	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
MELMHNEA_00997	5.53e-203	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
MELMHNEA_00998	5.38e-184	-	-	-	K	-	-	-	LysR substrate binding domain
MELMHNEA_00999	1.47e-70	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MELMHNEA_01000	1.41e-97	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MELMHNEA_01002	1.69e-94	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MELMHNEA_01003	1.29e-41	-	-	-	O	-	-	-	OsmC-like protein
MELMHNEA_01005	1.33e-44	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_01006	4.78e-261	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
MELMHNEA_01007	2.14e-103	-	-	-	-	-	-	-	-
MELMHNEA_01008	2.25e-91	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MELMHNEA_01014	5.72e-60	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MELMHNEA_01016	4.24e-22	-	-	-	M	-	-	-	LysM domain
MELMHNEA_01018	0.000221	wag31	-	-	D	-	-	-	PFAM DivIVA
MELMHNEA_01021	4.34e-166	-	-	-	S	-	-	-	Peptidase family M23
MELMHNEA_01022	5.37e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MELMHNEA_01023	2.8e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MELMHNEA_01024	8.12e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MELMHNEA_01025	2.86e-307	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MELMHNEA_01026	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
MELMHNEA_01027	5.4e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MELMHNEA_01028	1.65e-180	-	-	-	-	-	-	-	-
MELMHNEA_01029	2.54e-176	-	-	-	-	-	-	-	-
MELMHNEA_01030	3.85e-193	-	-	-	-	-	-	-	-
MELMHNEA_01031	3.49e-36	-	-	-	-	-	-	-	-
MELMHNEA_01032	1.27e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MELMHNEA_01033	4.01e-184	-	-	-	-	-	-	-	-
MELMHNEA_01034	4.4e-215	-	-	-	-	-	-	-	-
MELMHNEA_01035	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MELMHNEA_01036	1.28e-150	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MELMHNEA_01037	4.87e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MELMHNEA_01038	6.67e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MELMHNEA_01039	5.87e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MELMHNEA_01040	2.12e-173	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
MELMHNEA_01041	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MELMHNEA_01042	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MELMHNEA_01043	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MELMHNEA_01044	9.62e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MELMHNEA_01045	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MELMHNEA_01046	6.91e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MELMHNEA_01047	5.5e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MELMHNEA_01048	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MELMHNEA_01049	8.47e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MELMHNEA_01050	1.18e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MELMHNEA_01051	1.85e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MELMHNEA_01052	5.87e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MELMHNEA_01053	6.74e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MELMHNEA_01054	9.67e-104	-	-	-	-	-	-	-	-
MELMHNEA_01055	6.56e-86	sagB	-	-	C	-	-	-	Nitroreductase family
MELMHNEA_01057	1.28e-162	sagD	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
MELMHNEA_01059	5.61e-38	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MELMHNEA_01062	8.36e-62	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MELMHNEA_01067	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MELMHNEA_01069	5.3e-78	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	VirC1 protein
MELMHNEA_01070	7e-40	-	-	-	M	-	-	-	CHAP domain
MELMHNEA_01075	4.83e-27	-	-	-	-	-	-	-	-
MELMHNEA_01079	8.39e-36	-	-	-	M	-	-	-	LysM domain protein
MELMHNEA_01087	6.02e-85	-	-	-	-	-	-	-	-
MELMHNEA_01088	1.13e-48	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MELMHNEA_01089	5.14e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MELMHNEA_01090	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MELMHNEA_01091	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MELMHNEA_01092	2.74e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MELMHNEA_01093	1.14e-102	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MELMHNEA_01094	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MELMHNEA_01095	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MELMHNEA_01096	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MELMHNEA_01097	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MELMHNEA_01098	5.56e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
MELMHNEA_01099	2.36e-217	degV1	-	-	S	-	-	-	DegV family
MELMHNEA_01100	6.11e-171	-	-	-	V	-	-	-	ABC transporter transmembrane region
MELMHNEA_01101	4.76e-213	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MELMHNEA_01102	6.33e-17	-	-	-	S	-	-	-	CsbD-like
MELMHNEA_01103	2.26e-31	-	-	-	S	-	-	-	Transglycosylase associated protein
MELMHNEA_01104	1.37e-287	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MELMHNEA_01105	3.92e-153	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MELMHNEA_01107	6.48e-167	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_01108	4.95e-98	-	-	-	-	-	-	-	-
MELMHNEA_01109	6.59e-115	-	-	-	-	-	-	-	-
MELMHNEA_01110	2.67e-180	-	-	-	D	-	-	-	Ftsk spoiiie family protein
MELMHNEA_01111	1.74e-185	-	-	-	S	-	-	-	Replication initiation factor
MELMHNEA_01112	1.33e-72	-	-	-	-	-	-	-	-
MELMHNEA_01113	4.04e-36	-	-	-	-	-	-	-	-
MELMHNEA_01114	3.5e-280	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MELMHNEA_01116	9.75e-80	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MELMHNEA_01117	8.25e-65	-	-	-	V	ko:K01990,ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MELMHNEA_01119	9.13e-157	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
MELMHNEA_01121	7.01e-32	-	-	-	K	-	-	-	Transcriptional regulator
MELMHNEA_01122	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MELMHNEA_01123	3.74e-180	-	-	-	L	-	-	-	Transposase DDE domain
MELMHNEA_01126	3.31e-68	yidA	-	-	S	-	-	-	hydrolase
MELMHNEA_01127	2.3e-99	-	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MELMHNEA_01128	2.49e-68	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
MELMHNEA_01129	1.58e-67	pts36A	2.7.1.200, 2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02773	ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
MELMHNEA_01130	1.47e-08	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MELMHNEA_01131	2.07e-247	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	iic component
MELMHNEA_01133	5.12e-140	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
MELMHNEA_01139	5.06e-256	-	-	-	L	-	-	-	Transposase DDE domain
MELMHNEA_01140	5.38e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
MELMHNEA_01141	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_01142	3.51e-187	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
MELMHNEA_01143	1.46e-31	-	-	-	-	-	-	-	-
MELMHNEA_01144	7.19e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
MELMHNEA_01145	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
MELMHNEA_01146	2e-211	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
MELMHNEA_01147	1.6e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
MELMHNEA_01148	5.17e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MELMHNEA_01149	4.89e-196	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MELMHNEA_01150	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MELMHNEA_01151	5.26e-171	-	-	-	H	-	-	-	Aldolase/RraA
MELMHNEA_01152	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MELMHNEA_01153	1.66e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MELMHNEA_01154	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MELMHNEA_01155	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MELMHNEA_01156	2.34e-122	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MELMHNEA_01157	5.74e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MELMHNEA_01158	4.37e-205	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MELMHNEA_01159	1.33e-225	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MELMHNEA_01160	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MELMHNEA_01161	5.55e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MELMHNEA_01162	3.53e-228	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MELMHNEA_01163	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MELMHNEA_01164	8.44e-306	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MELMHNEA_01165	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
MELMHNEA_01166	6.04e-49	-	-	-	-	-	-	-	-
MELMHNEA_01168	1.46e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MELMHNEA_01169	7.94e-114	-	-	-	K	-	-	-	GNAT family
MELMHNEA_01170	3.7e-258	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
MELMHNEA_01171	1.49e-151	-	-	-	V	-	-	-	Abi-like protein
MELMHNEA_01173	1.34e-175	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_01174	1.3e-31	-	-	-	-	-	-	-	-
MELMHNEA_01175	2.61e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MELMHNEA_01176	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MELMHNEA_01177	3.56e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MELMHNEA_01178	5.23e-229	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MELMHNEA_01179	3.15e-259	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MELMHNEA_01180	2.81e-74	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MELMHNEA_01181	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
MELMHNEA_01182	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MELMHNEA_01183	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MELMHNEA_01184	9.37e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MELMHNEA_01185	7e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MELMHNEA_01186	5.5e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MELMHNEA_01187	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MELMHNEA_01188	1.39e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MELMHNEA_01189	1.45e-74	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_01195	5.95e-114	ymdB	-	-	S	-	-	-	Macro domain protein
MELMHNEA_01196	1.87e-288	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MELMHNEA_01197	7.62e-223	-	-	-	-	-	-	-	-
MELMHNEA_01198	2.2e-79	lysM	-	-	M	-	-	-	LysM domain
MELMHNEA_01199	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MELMHNEA_01200	1.52e-103	yveB	-	-	I	-	-	-	PAP2 superfamily
MELMHNEA_01201	5.68e-34	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MELMHNEA_01202	7.81e-186	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MELMHNEA_01203	2.4e-202	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MELMHNEA_01204	7.4e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MELMHNEA_01205	4.13e-178	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MELMHNEA_01206	3.12e-135	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MELMHNEA_01207	2.12e-153	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MELMHNEA_01208	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MELMHNEA_01209	6.04e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MELMHNEA_01210	8.69e-96	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MELMHNEA_01211	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MELMHNEA_01212	0.0	-	-	-	L	-	-	-	Transposase
MELMHNEA_01213	9.37e-77	-	-	-	-	-	-	-	-
MELMHNEA_01221	1.5e-84	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
MELMHNEA_01222	3.85e-27	-	-	-	L	-	-	-	Probable transposase
MELMHNEA_01228	3.45e-47	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MELMHNEA_01233	1.06e-316	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MELMHNEA_01234	1.86e-146	-	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MELMHNEA_01238	3.98e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MELMHNEA_01239	2.29e-274	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MELMHNEA_01240	9.66e-12	-	-	-	-	-	-	-	-
MELMHNEA_01241	2.02e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MELMHNEA_01245	1.93e-32	-	-	-	G	-	-	-	Peptidase_C39 like family
MELMHNEA_01246	2.16e-207	-	-	-	M	-	-	-	NlpC/P60 family
MELMHNEA_01247	6.67e-115	-	-	-	G	-	-	-	Peptidase_C39 like family
MELMHNEA_01248	1.09e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MELMHNEA_01249	2.05e-115	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MELMHNEA_01250	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_01251	1.05e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MELMHNEA_01252	1.92e-206	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MELMHNEA_01253	6.78e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MELMHNEA_01254	1.25e-244	ysdE	-	-	P	-	-	-	Citrate transporter
MELMHNEA_01255	1.59e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MELMHNEA_01256	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MELMHNEA_01257	9.69e-25	-	-	-	-	-	-	-	-
MELMHNEA_01258	5.31e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MELMHNEA_01259	1.04e-187	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
MELMHNEA_01260	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MELMHNEA_01261	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MELMHNEA_01263	2.13e-167	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MELMHNEA_01264	5.96e-283	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MELMHNEA_01265	1.97e-315	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MELMHNEA_01267	4.65e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MELMHNEA_01268	7.25e-309	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MELMHNEA_01269	2.82e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MELMHNEA_01270	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MELMHNEA_01271	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MELMHNEA_01272	1.76e-165	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MELMHNEA_01273	1.38e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MELMHNEA_01274	4e-204	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MELMHNEA_01275	1.74e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MELMHNEA_01276	3.16e-52	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MELMHNEA_01277	4.91e-111	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MELMHNEA_01278	5.79e-217	-	-	-	K	-	-	-	LysR substrate binding domain
MELMHNEA_01279	4.86e-157	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MELMHNEA_01280	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MELMHNEA_01281	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MELMHNEA_01282	1.47e-66	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MELMHNEA_01284	2.71e-297	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MELMHNEA_01285	1.23e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MELMHNEA_01286	5.86e-131	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MELMHNEA_01287	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MELMHNEA_01288	7.33e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MELMHNEA_01289	1.09e-46	-	-	-	-	-	-	-	-
MELMHNEA_01290	1.44e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MELMHNEA_01291	2.45e-90	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MELMHNEA_01292	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MELMHNEA_01293	6.58e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MELMHNEA_01294	4.61e-104	-	-	-	K	-	-	-	acetyltransferase
MELMHNEA_01295	1.69e-61	-	-	-	F	-	-	-	AAA domain
MELMHNEA_01296	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MELMHNEA_01297	2.07e-196	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
MELMHNEA_01298	8.34e-294	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MELMHNEA_01299	9.63e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MELMHNEA_01300	1.1e-54	-	-	-	K	-	-	-	Helix-turn-helix
MELMHNEA_01301	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MELMHNEA_01303	1.89e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MELMHNEA_01304	4.21e-148	-	-	-	M	-	-	-	Rib/alpha-like repeat
MELMHNEA_01305	1.38e-225	-	-	-	M	-	-	-	Rib/alpha-like repeat
MELMHNEA_01306	1.82e-05	-	-	-	-	-	-	-	-
MELMHNEA_01307	3.56e-47	-	-	-	-	-	-	-	-
MELMHNEA_01308	4.13e-83	-	-	-	-	-	-	-	-
MELMHNEA_01311	1.51e-159	-	-	-	-	-	-	-	-
MELMHNEA_01312	4.83e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
MELMHNEA_01313	1.24e-08	-	-	-	-	-	-	-	-
MELMHNEA_01314	1.73e-48	-	-	-	-	-	-	-	-
MELMHNEA_01315	0.0	snf	-	-	KL	-	-	-	domain protein
MELMHNEA_01316	9.39e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MELMHNEA_01317	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MELMHNEA_01318	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MELMHNEA_01319	1.11e-234	-	-	-	K	-	-	-	Transcriptional regulator
MELMHNEA_01320	1.05e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MELMHNEA_01321	1.17e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MELMHNEA_01322	5.03e-76	-	-	-	K	-	-	-	Helix-turn-helix domain
MELMHNEA_01323	6.59e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MELMHNEA_01324	1.88e-157	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MELMHNEA_01325	3.24e-290	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
MELMHNEA_01326	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MELMHNEA_01327	5.41e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_01328	2.1e-31	-	-	-	-	-	-	-	-
MELMHNEA_01329	1.69e-06	-	-	-	-	-	-	-	-
MELMHNEA_01330	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MELMHNEA_01331	3.78e-230	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MELMHNEA_01332	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MELMHNEA_01333	8.03e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MELMHNEA_01334	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_01335	1.21e-19	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_01336	5.76e-144	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_01337	2.26e-148	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_01338	9.69e-177	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MELMHNEA_01339	1.6e-220	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MELMHNEA_01340	2.2e-227	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MELMHNEA_01341	5.15e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MELMHNEA_01342	4.4e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MELMHNEA_01343	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MELMHNEA_01344	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MELMHNEA_01345	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MELMHNEA_01346	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MELMHNEA_01347	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MELMHNEA_01348	3.12e-41	-	-	-	-	-	-	-	-
MELMHNEA_01349	3.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MELMHNEA_01350	2.61e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MELMHNEA_01351	1.03e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MELMHNEA_01352	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MELMHNEA_01353	1.98e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MELMHNEA_01354	7.82e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MELMHNEA_01355	5.15e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MELMHNEA_01356	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MELMHNEA_01357	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MELMHNEA_01358	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MELMHNEA_01359	2.19e-100	-	-	-	S	-	-	-	ASCH
MELMHNEA_01360	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MELMHNEA_01361	1.83e-190	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MELMHNEA_01362	4.47e-196	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MELMHNEA_01363	4.4e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MELMHNEA_01364	1.26e-237	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MELMHNEA_01365	8.47e-182	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MELMHNEA_01366	3.38e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MELMHNEA_01367	1.32e-91	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MELMHNEA_01368	2.11e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MELMHNEA_01369	2.14e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MELMHNEA_01370	3.94e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MELMHNEA_01371	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MELMHNEA_01372	5.24e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MELMHNEA_01373	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MELMHNEA_01374	1.75e-164	-	-	-	M	-	-	-	Rib/alpha-like repeat
MELMHNEA_01375	4.6e-74	-	-	-	M	-	-	-	Rib/alpha-like repeat
MELMHNEA_01376	9.48e-31	-	-	-	-	-	-	-	-
MELMHNEA_01377	4.01e-84	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
MELMHNEA_01378	5.51e-46	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
MELMHNEA_01379	1.28e-311	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
MELMHNEA_01381	1.35e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
MELMHNEA_01382	4.18e-155	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MELMHNEA_01383	2.05e-248	-	-	-	-	-	-	-	-
MELMHNEA_01384	3.8e-315	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MELMHNEA_01385	3.31e-299	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MELMHNEA_01386	7.29e-220	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_01387	4.2e-93	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MELMHNEA_01388	4.5e-107	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MELMHNEA_01389	9.84e-108	-	-	-	L	-	-	-	Resolvase, N-terminal
MELMHNEA_01390	1.86e-197	-	-	-	M	-	-	-	Peptidase family M1 domain
MELMHNEA_01391	1.79e-245	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MELMHNEA_01392	2.39e-26	-	-	-	-	-	-	-	-
MELMHNEA_01393	1.8e-66	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MELMHNEA_01394	2.27e-191	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MELMHNEA_01395	1.62e-250	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MELMHNEA_01396	3.03e-110	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MELMHNEA_01397	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MELMHNEA_01398	1.12e-136	-	-	-	M	-	-	-	family 8
MELMHNEA_01399	1.15e-47	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
MELMHNEA_01400	1.55e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MELMHNEA_01401	3.08e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MELMHNEA_01402	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MELMHNEA_01403	1.29e-143	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MELMHNEA_01404	7.55e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MELMHNEA_01405	3.99e-197	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MELMHNEA_01406	1.4e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MELMHNEA_01407	8.75e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MELMHNEA_01408	3e-167	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MELMHNEA_01409	8.72e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MELMHNEA_01410	1.83e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MELMHNEA_01411	4.59e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MELMHNEA_01412	1.42e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MELMHNEA_01413	2.44e-64	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MELMHNEA_01414	8.98e-214	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MELMHNEA_01415	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MELMHNEA_01416	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MELMHNEA_01417	8.74e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MELMHNEA_01418	2.16e-163	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MELMHNEA_01419	5.7e-282	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MELMHNEA_01420	1.05e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_01421	1.61e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MELMHNEA_01422	1.2e-41	-	-	-	-	-	-	-	-
MELMHNEA_01423	1.09e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MELMHNEA_01424	5.74e-96	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
MELMHNEA_01425	0.0	-	-	-	-	-	-	-	-
MELMHNEA_01426	9.67e-33	-	-	-	S	-	-	-	Domain of unknown function DUF1829
MELMHNEA_01428	4.53e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MELMHNEA_01429	0.0	yhaN	-	-	L	-	-	-	AAA domain
MELMHNEA_01430	6.56e-293	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MELMHNEA_01431	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MELMHNEA_01432	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MELMHNEA_01433	2.09e-208	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MELMHNEA_01434	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MELMHNEA_01435	1.49e-13	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MELMHNEA_01436	1.91e-102	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MELMHNEA_01437	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MELMHNEA_01438	4.95e-164	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MELMHNEA_01439	3.11e-250	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MELMHNEA_01440	1.28e-226	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MELMHNEA_01441	5.19e-248	-	-	-	G	-	-	-	Transmembrane secretion effector
MELMHNEA_01442	5.63e-171	-	-	-	V	-	-	-	ABC transporter transmembrane region
MELMHNEA_01444	1.01e-45	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_01445	1.88e-44	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
MELMHNEA_01448	2.23e-189	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MELMHNEA_01450	4.11e-124	potE	-	-	E	-	-	-	thought to be involved in transport amino acids across the membrane
MELMHNEA_01452	2.67e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MELMHNEA_01453	6.66e-27	-	-	-	S	-	-	-	CAAX protease self-immunity
MELMHNEA_01455	2.84e-108	-	-	-	K	-	-	-	FR47-like protein
MELMHNEA_01456	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MELMHNEA_01457	1.43e-310	ynbB	-	-	P	-	-	-	aluminum resistance
MELMHNEA_01458	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MELMHNEA_01459	0.0	-	-	-	E	-	-	-	Amino acid permease
MELMHNEA_01460	9.58e-122	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
MELMHNEA_01461	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MELMHNEA_01462	3.03e-145	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MELMHNEA_01463	1.31e-16	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MELMHNEA_01464	2.95e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MELMHNEA_01465	7.64e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MELMHNEA_01466	2.15e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MELMHNEA_01467	4.52e-237	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MELMHNEA_01468	4.86e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MELMHNEA_01469	2.15e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MELMHNEA_01470	1.1e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MELMHNEA_01471	6.48e-136	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MELMHNEA_01472	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MELMHNEA_01473	9.89e-74	-	-	-	-	-	-	-	-
MELMHNEA_01474	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MELMHNEA_01475	1.23e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MELMHNEA_01476	1.6e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MELMHNEA_01479	8.95e-70	-	-	-	K	-	-	-	LytTr DNA-binding domain
MELMHNEA_01480	9.29e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MELMHNEA_01481	1.08e-217	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MELMHNEA_01482	2.25e-30	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
MELMHNEA_01483	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MELMHNEA_01489	1.23e-117	-	-	-	U	-	-	-	TraM recognition site of TraD and TraG
MELMHNEA_01491	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
MELMHNEA_01492	2.51e-52	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MELMHNEA_01493	7.63e-43	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MELMHNEA_01494	1.48e-210	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MELMHNEA_01495	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MELMHNEA_01496	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MELMHNEA_01497	3.56e-281	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MELMHNEA_01498	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MELMHNEA_01499	3.51e-218	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MELMHNEA_01500	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
MELMHNEA_01501	7.25e-276	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MELMHNEA_01502	3.47e-19	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
MELMHNEA_01504	4.83e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MELMHNEA_01505	6.51e-114	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MELMHNEA_01506	1.02e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MELMHNEA_01507	3.92e-110	usp5	-	-	T	-	-	-	universal stress protein
MELMHNEA_01509	1.78e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
MELMHNEA_01510	6.34e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MELMHNEA_01511	4.7e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MELMHNEA_01512	1.06e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MELMHNEA_01513	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
MELMHNEA_01514	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MELMHNEA_01515	4.37e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
MELMHNEA_01516	1.14e-55	-	-	-	-	-	-	-	-
MELMHNEA_01517	2.2e-171	-	-	-	-	-	-	-	-
MELMHNEA_01518	6.86e-276	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
MELMHNEA_01519	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MELMHNEA_01520	1.51e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MELMHNEA_01521	1.66e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MELMHNEA_01522	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
MELMHNEA_01523	1.05e-45	-	-	-	-	-	-	-	-
MELMHNEA_01524	1.2e-199	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MELMHNEA_01525	6.13e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MELMHNEA_01526	4.39e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
MELMHNEA_01528	5.01e-55	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MELMHNEA_01529	2.3e-96	-	-	-	M	-	-	-	LysM domain
MELMHNEA_01530	3.3e-42	-	-	-	-	-	-	-	-
MELMHNEA_01534	4.47e-273	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MELMHNEA_01535	1.51e-235	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MELMHNEA_01536	8.81e-299	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MELMHNEA_01538	9e-33	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MELMHNEA_01539	2.64e-266	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MELMHNEA_01540	1.34e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MELMHNEA_01541	7.82e-240	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MELMHNEA_01542	7.1e-252	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MELMHNEA_01543	6.54e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MELMHNEA_01544	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MELMHNEA_01545	3.4e-93	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MELMHNEA_01546	8.08e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MELMHNEA_01547	1.17e-143	-	-	-	-	-	-	-	-
MELMHNEA_01549	7.04e-145	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
MELMHNEA_01550	4.07e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MELMHNEA_01551	1.5e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
MELMHNEA_01552	4.57e-135	-	-	-	S	ko:K06872	-	ko00000	TPM domain
MELMHNEA_01553	1.71e-173	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MELMHNEA_01554	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MELMHNEA_01555	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MELMHNEA_01556	2.72e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MELMHNEA_01557	5.17e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MELMHNEA_01558	8.93e-194	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MELMHNEA_01559	9.99e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MELMHNEA_01560	2.05e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MELMHNEA_01561	1.81e-307	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MELMHNEA_01567	5.1e-07	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
MELMHNEA_01568	2.9e-50	-	-	-	M	-	-	-	Psort location Cellwall, score
MELMHNEA_01569	1.5e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MELMHNEA_01570	1.32e-85	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MELMHNEA_01584	2.27e-179	-	-	-	-	-	-	-	-
MELMHNEA_01588	3.15e-48	-	-	-	-	-	-	-	-
MELMHNEA_01589	9.86e-74	-	-	-	S	-	-	-	Cupredoxin-like domain
MELMHNEA_01590	3.27e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
MELMHNEA_01591	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MELMHNEA_01592	6.63e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
MELMHNEA_01593	3.14e-137	-	-	-	-	-	-	-	-
MELMHNEA_01594	1.83e-316	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MELMHNEA_01595	6.46e-27	-	-	-	-	-	-	-	-
MELMHNEA_01596	3.91e-269	-	-	-	-	-	-	-	-
MELMHNEA_01597	6.57e-175	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_01598	1.14e-154	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_01599	4.54e-135	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MELMHNEA_01600	4.75e-58	-	-	-	-	-	-	-	-
MELMHNEA_01601	8.29e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_01602	1.21e-42	-	-	-	E	-	-	-	Zn peptidase
MELMHNEA_01603	1.45e-36	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MELMHNEA_01604	1.73e-79	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MELMHNEA_01605	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MELMHNEA_01606	5.22e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MELMHNEA_01607	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MELMHNEA_01608	3.07e-235	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MELMHNEA_01609	0.0	-	-	-	L	-	-	-	Nuclease-related domain
MELMHNEA_01610	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MELMHNEA_01611	2.31e-148	-	-	-	S	-	-	-	repeat protein
MELMHNEA_01612	4.7e-163	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
MELMHNEA_01613	4.47e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MELMHNEA_01614	9.98e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MELMHNEA_01615	1.62e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MELMHNEA_01616	2.05e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MELMHNEA_01617	1.22e-55	-	-	-	-	-	-	-	-
MELMHNEA_01618	4.26e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MELMHNEA_01619	2.32e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MELMHNEA_01620	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MELMHNEA_01621	6.3e-138	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MELMHNEA_01622	1.9e-190	ylmH	-	-	S	-	-	-	S4 domain protein
MELMHNEA_01623	2.42e-60	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MELMHNEA_01624	1.43e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MELMHNEA_01625	2.52e-300	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MELMHNEA_01626	1.54e-309	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MELMHNEA_01627	3.14e-194	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MELMHNEA_01628	1.65e-265	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MELMHNEA_01629	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MELMHNEA_01630	4.43e-224	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MELMHNEA_01631	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MELMHNEA_01632	6.55e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MELMHNEA_01633	1.49e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MELMHNEA_01634	5.63e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MELMHNEA_01635	1.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
MELMHNEA_01636	1.4e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MELMHNEA_01637	5.43e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
MELMHNEA_01638	4.78e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MELMHNEA_01639	8.26e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MELMHNEA_01640	6.18e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MELMHNEA_01641	1.06e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MELMHNEA_01642	1.22e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MELMHNEA_01643	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MELMHNEA_01644	3.7e-45	-	-	-	-	-	-	-	-
MELMHNEA_01645	1.73e-165	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MELMHNEA_01646	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MELMHNEA_01647	9.25e-13	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MELMHNEA_01648	2.09e-59	-	-	-	-	-	-	-	-
MELMHNEA_01649	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
MELMHNEA_01650	1.73e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MELMHNEA_01651	1.06e-86	-	-	-	S	-	-	-	GtrA-like protein
MELMHNEA_01652	9.08e-56	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MELMHNEA_01653	6.01e-153	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MELMHNEA_01654	4.26e-197	-	-	-	-	-	-	-	-
MELMHNEA_01655	9.51e-61	-	-	-	-	-	-	-	-
MELMHNEA_01656	1.23e-52	-	-	-	K	-	-	-	Helix-turn-helix domain
MELMHNEA_01657	1.93e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF3232)
MELMHNEA_01658	2.06e-77	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MELMHNEA_01659	1.18e-80	-	-	-	-	-	-	-	-
MELMHNEA_01660	0.0	-	-	-	-	-	-	-	-
MELMHNEA_01661	9.84e-123	-	-	-	-	-	-	-	-
MELMHNEA_01662	8.09e-196	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_01663	5.74e-142	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_01664	3.83e-177	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_01665	9.42e-103	-	-	-	-	-	-	-	-
MELMHNEA_01666	5.22e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MELMHNEA_01667	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MELMHNEA_01668	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MELMHNEA_01669	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MELMHNEA_01670	4.95e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MELMHNEA_01671	1.56e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MELMHNEA_01672	3.81e-123	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MELMHNEA_01673	1.19e-45	-	-	-	-	-	-	-	-
MELMHNEA_01674	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MELMHNEA_01675	1.52e-87	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MELMHNEA_01676	1.34e-310	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MELMHNEA_01677	3.73e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MELMHNEA_01678	1.23e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MELMHNEA_01679	3.82e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MELMHNEA_01680	1.05e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MELMHNEA_01681	5.48e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MELMHNEA_01682	2.29e-210	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MELMHNEA_01683	3.01e-197	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MELMHNEA_01684	5.24e-187	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MELMHNEA_01685	3.83e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MELMHNEA_01686	2.89e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MELMHNEA_01687	8.49e-85	-	-	-	E	-	-	-	amino acid
MELMHNEA_01688	6.08e-161	yagE	-	-	E	-	-	-	Amino acid permease
MELMHNEA_01689	1.86e-111	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
MELMHNEA_01690	3.86e-204	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MELMHNEA_01691	5.13e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MELMHNEA_01692	1.8e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MELMHNEA_01693	8.63e-191	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MELMHNEA_01694	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MELMHNEA_01695	3.67e-88	-	-	-	P	-	-	-	NhaP-type Na H and K H
MELMHNEA_01696	7.2e-49	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MELMHNEA_01697	2.4e-118	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MELMHNEA_01698	2.15e-198	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MELMHNEA_01699	1e-168	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MELMHNEA_01700	1.5e-195	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MELMHNEA_01701	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MELMHNEA_01702	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MELMHNEA_01703	5.99e-180	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MELMHNEA_01704	4.67e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MELMHNEA_01705	1.4e-313	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MELMHNEA_01706	9.4e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MELMHNEA_01707	6.42e-110	-	-	-	C	-	-	-	Aldo keto reductase
MELMHNEA_01708	8.85e-121	-	-	-	M	-	-	-	LysM domain protein
MELMHNEA_01709	8.59e-112	-	-	-	GKT	-	-	-	domain protein
MELMHNEA_01710	0.0	-	3.2.1.170, 3.2.1.24	GH38	G	ko:K01191,ko:K15524	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolases family 38 N-terminal domain
MELMHNEA_01711	4.34e-198	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	system, fructose-specific IIC component
MELMHNEA_01712	5.84e-50	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 9.98
MELMHNEA_01713	2.4e-54	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MELMHNEA_01714	1.13e-201	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MELMHNEA_01715	2.91e-83	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MELMHNEA_01716	8.64e-85	yybA	-	-	K	-	-	-	Transcriptional regulator
MELMHNEA_01717	8e-108	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MELMHNEA_01718	5.59e-109	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MELMHNEA_01719	5.81e-98	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MELMHNEA_01720	2.37e-242	-	-	-	T	-	-	-	GHKL domain
MELMHNEA_01721	1.75e-168	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MELMHNEA_01722	1.28e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MELMHNEA_01723	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MELMHNEA_01724	2.15e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
MELMHNEA_01725	1.75e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MELMHNEA_01726	1.83e-91	-	-	-	V	-	-	-	ABC transporter transmembrane region
MELMHNEA_01727	6.69e-84	-	-	-	L	-	-	-	RelB antitoxin
MELMHNEA_01728	1.51e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
MELMHNEA_01729	8.6e-108	-	-	-	M	-	-	-	NlpC/P60 family
MELMHNEA_01732	1.02e-200	-	-	-	-	-	-	-	-
MELMHNEA_01733	1.03e-07	-	-	-	-	-	-	-	-
MELMHNEA_01734	5.51e-47	-	-	-	-	-	-	-	-
MELMHNEA_01735	4.48e-206	-	-	-	EG	-	-	-	EamA-like transporter family
MELMHNEA_01736	3.18e-209	-	-	-	EG	-	-	-	EamA-like transporter family
MELMHNEA_01737	3.75e-178	yicL	-	-	EG	-	-	-	EamA-like transporter family
MELMHNEA_01738	1.32e-137	-	-	-	-	-	-	-	-
MELMHNEA_01739	9.07e-143	-	-	-	-	-	-	-	-
MELMHNEA_01740	1.84e-238	-	-	-	S	-	-	-	DUF218 domain
MELMHNEA_01741	0.0	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
MELMHNEA_01742	8.23e-112	-	-	-	-	-	-	-	-
MELMHNEA_01743	1.09e-74	-	-	-	-	-	-	-	-
MELMHNEA_01744	7.26e-35	-	-	-	S	-	-	-	Protein conserved in bacteria
MELMHNEA_01745	2.27e-71	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
MELMHNEA_01746	7.1e-136	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MELMHNEA_01747	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MELMHNEA_01748	3.46e-32	-	-	-	S	-	-	-	Alpha beta hydrolase
MELMHNEA_01749	1.47e-303	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MELMHNEA_01750	2.29e-88	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MELMHNEA_01751	2.56e-66	-	-	-	M	-	-	-	Domain of unknown function (DUF1919)
MELMHNEA_01752	2.38e-130	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MELMHNEA_01753	2.82e-97	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
MELMHNEA_01754	8.19e-64	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
MELMHNEA_01755	1.18e-199	-	-	-	M	-	-	-	Glycosyltransferase
MELMHNEA_01756	6.65e-155	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
MELMHNEA_01757	6.64e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MELMHNEA_01758	2.78e-160	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MELMHNEA_01759	3.05e-184	epsB	-	-	M	-	-	-	biosynthesis protein
MELMHNEA_01760	1.47e-243	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MELMHNEA_01761	3.39e-88	-	-	-	S	ko:K06915	-	ko00000	cog cog0433
MELMHNEA_01762	9.86e-146	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MELMHNEA_01763	8.81e-40	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
MELMHNEA_01765	1.61e-70	-	-	-	-	-	-	-	-
MELMHNEA_01766	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MELMHNEA_01767	6.39e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MELMHNEA_01768	2.28e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MELMHNEA_01769	4.13e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MELMHNEA_01770	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MELMHNEA_01771	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MELMHNEA_01772	2.06e-88	-	-	-	-	-	-	-	-
MELMHNEA_01773	1.15e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
MELMHNEA_01774	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MELMHNEA_01775	1.24e-258	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MELMHNEA_01776	3.03e-90	-	-	-	-	-	-	-	-
MELMHNEA_01777	4.36e-142	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
MELMHNEA_01778	4.08e-270	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MELMHNEA_01779	7.55e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
MELMHNEA_01780	1.18e-95	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
MELMHNEA_01782	5.89e-316	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
MELMHNEA_01783	1.22e-195	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MELMHNEA_01784	4.48e-174	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MELMHNEA_01785	7.05e-146	potC3	-	-	E	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MELMHNEA_01789	4.4e-108	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MELMHNEA_01790	4.11e-28	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MELMHNEA_01791	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MELMHNEA_01792	2.09e-129	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
MELMHNEA_01793	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MELMHNEA_01794	2.76e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MELMHNEA_01795	1.13e-241	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
MELMHNEA_01796	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MELMHNEA_01797	5.74e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MELMHNEA_01798	1.87e-290	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MELMHNEA_01799	7.89e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MELMHNEA_01800	3.1e-127	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MELMHNEA_01801	1.59e-259	pbpX1	-	-	V	-	-	-	Beta-lactamase
MELMHNEA_01802	1.12e-149	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MELMHNEA_01803	1.12e-104	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MELMHNEA_01804	2.26e-153	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MELMHNEA_01805	6.66e-149	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MELMHNEA_01806	6.74e-239	-	-	-	M	-	-	-	Glycosyl transferase
MELMHNEA_01807	7.21e-45	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MELMHNEA_01808	5.46e-167	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MELMHNEA_01809	2.61e-153	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MELMHNEA_01810	5.09e-206	-	-	-	L	-	-	-	HNH nucleases
MELMHNEA_01811	8.49e-146	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MELMHNEA_01812	1.13e-41	-	-	-	M	-	-	-	Lysin motif
MELMHNEA_01813	5.6e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MELMHNEA_01814	1.4e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MELMHNEA_01815	1.34e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MELMHNEA_01816	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MELMHNEA_01817	7.11e-293	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MELMHNEA_01818	2e-299	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MELMHNEA_01819	3.68e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
MELMHNEA_01820	1.54e-158	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MELMHNEA_01821	1.53e-232	-	-	-	-	-	-	-	-
MELMHNEA_01822	0.0	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MELMHNEA_01825	7.62e-306	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
MELMHNEA_01826	1.48e-14	-	-	-	-	-	-	-	-
MELMHNEA_01827	5.24e-31	-	-	-	S	-	-	-	transposase or invertase
MELMHNEA_01828	9.6e-309	slpX	-	-	S	-	-	-	SLAP domain
MELMHNEA_01829	1.43e-186	-	-	-	K	-	-	-	SIS domain
MELMHNEA_01830	3.01e-154	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MELMHNEA_01831	1.03e-237	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MELMHNEA_01832	1.93e-266	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MELMHNEA_01834	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MELMHNEA_01836	2.67e-148	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MELMHNEA_01837	7.75e-153	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MELMHNEA_01838	9.01e-115	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
MELMHNEA_01839	8.92e-136	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MELMHNEA_01840	2.82e-211	-	-	-	D	-	-	-	nuclear chromosome segregation
MELMHNEA_01841	1.33e-130	-	-	-	M	-	-	-	LysM domain protein
MELMHNEA_01842	1.64e-120	-	-	-	-	-	-	-	-
MELMHNEA_01843	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
MELMHNEA_01844	8.28e-176	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MELMHNEA_01845	4.71e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MELMHNEA_01846	1.88e-132	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MELMHNEA_01847	1.52e-105	-	-	-	L	-	-	-	MgsA AAA+ ATPase C terminal
MELMHNEA_01848	7.26e-287	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MELMHNEA_01850	2.77e-135	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MELMHNEA_01851	5.45e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MELMHNEA_01852	6.16e-14	-	-	-	-	-	-	-	-
MELMHNEA_01853	0.000386	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Psort location Cytoplasmic, score 9.98
MELMHNEA_01854	2.94e-94	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
MELMHNEA_01856	1.57e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_01857	9.48e-45	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MELMHNEA_01860	2.41e-39	-	-	-	-	-	-	-	-
MELMHNEA_01861	5.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MELMHNEA_01862	5.61e-72	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
MELMHNEA_01863	1.85e-164	yobV3	-	-	K	-	-	-	WYL domain
MELMHNEA_01864	2.6e-110	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
MELMHNEA_01865	1.45e-102	dpsB	-	-	P	-	-	-	Belongs to the Dps family
MELMHNEA_01866	4.22e-41	-	-	-	C	-	-	-	Heavy-metal-associated domain
MELMHNEA_01867	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
MELMHNEA_01868	6.34e-40	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
MELMHNEA_01869	1.03e-34	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
MELMHNEA_01870	1.77e-220	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MELMHNEA_01872	7.11e-227	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MELMHNEA_01873	1.31e-128	-	-	-	I	-	-	-	PAP2 superfamily
MELMHNEA_01874	1.14e-192	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MELMHNEA_01875	3.52e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MELMHNEA_01876	2.32e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MELMHNEA_01877	3.47e-49	yfhC	-	-	C	-	-	-	nitroreductase
MELMHNEA_01878	8.12e-48	yfhC	-	-	C	-	-	-	nitroreductase
MELMHNEA_01879	1.22e-174	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MELMHNEA_01880	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MELMHNEA_01881	1.8e-284	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MELMHNEA_01882	9.5e-153	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MELMHNEA_01883	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MELMHNEA_01884	4.04e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
MELMHNEA_01885	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MELMHNEA_01886	2.92e-79	-	-	-	-	-	-	-	-
MELMHNEA_01887	2.77e-25	-	-	-	-	-	-	-	-
MELMHNEA_01888	1.21e-40	-	-	-	-	-	-	-	-
MELMHNEA_01889	1.05e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MELMHNEA_01890	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MELMHNEA_01891	5.56e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MELMHNEA_01892	2.32e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MELMHNEA_01893	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MELMHNEA_01894	1.71e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MELMHNEA_01895	1.98e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MELMHNEA_01896	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MELMHNEA_01897	1.66e-268	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_01898	6.64e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MELMHNEA_01899	6.01e-147	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MELMHNEA_01900	9.14e-317	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MELMHNEA_01901	8.11e-245	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MELMHNEA_01902	0.0	-	-	-	S	-	-	-	SH3-like domain
MELMHNEA_01903	3.16e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_01904	4.76e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MELMHNEA_01905	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MELMHNEA_01906	1.07e-57	-	-	-	-	-	-	-	-
MELMHNEA_01907	1.13e-218	-	-	-	GK	-	-	-	ROK family
MELMHNEA_01908	3.49e-222	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MELMHNEA_01909	0.0	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_01910	5.52e-113	-	-	-	-	-	-	-	-
MELMHNEA_01911	7.9e-255	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MELMHNEA_01912	2.61e-23	-	-	-	-	-	-	-	-
MELMHNEA_01913	1.05e-119	-	-	-	S	-	-	-	membrane
MELMHNEA_01914	6.45e-93	-	-	-	K	-	-	-	LytTr DNA-binding domain
MELMHNEA_01917	5.94e-100	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
MELMHNEA_01918	2.25e-57	-	-	-	K	-	-	-	Tetracycline repressor, C-terminal all-alpha domain
MELMHNEA_01920	3.49e-113	-	-	-	K	-	-	-	LysR substrate binding domain
MELMHNEA_01921	1.59e-44	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
MELMHNEA_01922	1.17e-87	-	-	-	GM	-	-	-	NAD(P)H-binding
MELMHNEA_01923	1.64e-169	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MELMHNEA_01924	1.44e-62	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MELMHNEA_01925	3.21e-175	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MELMHNEA_01926	7.7e-126	-	-	-	L	-	-	-	Helix-turn-helix domain
MELMHNEA_01927	1.38e-131	-	-	-	-	-	-	-	-
MELMHNEA_01930	2.45e-212	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MELMHNEA_01933	1.72e-285	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MELMHNEA_01934	5.03e-313	mdr	-	-	EGP	-	-	-	Major Facilitator
MELMHNEA_01935	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MELMHNEA_01936	1.54e-194	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MELMHNEA_01937	7.56e-225	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Beta-lactamase
MELMHNEA_01938	5.06e-237	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
MELMHNEA_01939	3.22e-185	-	-	-	K	-	-	-	rpiR family
MELMHNEA_01940	1.29e-27	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MELMHNEA_01941	1.92e-212	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MELMHNEA_01942	1.44e-164	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MELMHNEA_01943	4.67e-54	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MELMHNEA_01944	9.07e-51	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MELMHNEA_01945	5.41e-56	-	-	-	-	-	-	-	-
MELMHNEA_01947	4.36e-99	-	-	-	L	-	-	-	Integrase
MELMHNEA_01952	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MELMHNEA_01953	4.35e-185	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MELMHNEA_01954	4.71e-239	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MELMHNEA_01955	4.05e-209	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MELMHNEA_01956	5.55e-137	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
MELMHNEA_01957	1.65e-241	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
MELMHNEA_01958	4.9e-99	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MELMHNEA_01959	1.64e-101	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MELMHNEA_01960	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MELMHNEA_01961	3.3e-72	-	-	-	-	-	-	-	-
MELMHNEA_01962	3.31e-154	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MELMHNEA_01963	8.06e-110	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MELMHNEA_01964	2.29e-162	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MELMHNEA_01965	3.69e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
MELMHNEA_01966	5.05e-11	-	-	-	-	-	-	-	-
MELMHNEA_01967	3.58e-61	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
MELMHNEA_01968	2.18e-122	yneE	-	-	K	-	-	-	Transcriptional regulator
MELMHNEA_01969	3.87e-80	yneE	-	-	K	-	-	-	Transcriptional regulator
MELMHNEA_01970	9.01e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MELMHNEA_01971	8.73e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MELMHNEA_01972	1.28e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MELMHNEA_01973	2.29e-112	-	-	-	-	-	-	-	-
MELMHNEA_01974	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MELMHNEA_01975	1.24e-232	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MELMHNEA_01976	5.07e-190	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MELMHNEA_01977	9.18e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MELMHNEA_01978	2.62e-199	epsV	-	-	S	-	-	-	glycosyl transferase family 2
MELMHNEA_01979	5.29e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MELMHNEA_01981	1.15e-44	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
MELMHNEA_01982	9.17e-41	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MELMHNEA_01983	1.57e-26	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MELMHNEA_01987	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MELMHNEA_01988	1.46e-117	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MELMHNEA_01989	2.93e-223	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MELMHNEA_01990	2.5e-203	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MELMHNEA_01991	4.63e-32	-	-	-	-	-	-	-	-
MELMHNEA_01992	6.72e-177	-	-	-	EP	-	-	-	Plasmid replication protein
MELMHNEA_01993	8.28e-102	-	-	-	S	-	-	-	helix_turn_helix, Deoxyribose operon repressor
MELMHNEA_01994	4.97e-64	-	-	-	S	-	-	-	Metal binding domain of Ada
MELMHNEA_01995	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MELMHNEA_01996	6.12e-177	lysR5	-	-	K	-	-	-	LysR substrate binding domain
MELMHNEA_01997	2.06e-298	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MELMHNEA_01998	5.39e-84	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MELMHNEA_01999	2.01e-135	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MELMHNEA_02000	1.76e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MELMHNEA_02001	1.07e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
MELMHNEA_02002	4.04e-29	-	-	-	-	-	-	-	-
MELMHNEA_02003	6.93e-140	-	-	-	K	-	-	-	LysR substrate binding domain
MELMHNEA_02004	1.13e-126	-	-	-	-	-	-	-	-
MELMHNEA_02005	5.04e-154	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MELMHNEA_02006	5.73e-153	-	-	-	-	-	-	-	-
MELMHNEA_02007	1.12e-213	-	-	-	EGP	-	-	-	Major Facilitator
MELMHNEA_02008	1.66e-44	-	-	-	K	-	-	-	Transcriptional regulator
MELMHNEA_02009	2.97e-110	-	-	-	-	-	-	-	-
MELMHNEA_02013	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MELMHNEA_02014	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MELMHNEA_02015	2.42e-40	-	-	-	-	-	-	-	-
MELMHNEA_02016	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MELMHNEA_02017	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MELMHNEA_02018	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MELMHNEA_02019	3.37e-192	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MELMHNEA_02020	2.65e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MELMHNEA_02021	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MELMHNEA_02022	3.43e-187	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
MELMHNEA_02024	0.0	XK27_00500	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a
MELMHNEA_02026	4.18e-208	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MELMHNEA_02027	1.79e-74	-	-	-	L	-	-	-	Resolvase, N-terminal
MELMHNEA_02029	2.59e-80	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MELMHNEA_02030	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MELMHNEA_02031	5.59e-98	-	-	-	-	-	-	-	-
MELMHNEA_02032	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MELMHNEA_02033	1.31e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MELMHNEA_02034	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
MELMHNEA_02035	3.04e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MELMHNEA_02036	2.16e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MELMHNEA_02037	2.24e-198	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MELMHNEA_02038	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MELMHNEA_02039	1.05e-40	-	-	-	-	-	-	-	-
MELMHNEA_02041	1.65e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MELMHNEA_02042	1.43e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MELMHNEA_02043	5.93e-302	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MELMHNEA_02045	0.0	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_02046	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
MELMHNEA_02047	1.35e-208	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MELMHNEA_02048	5.22e-54	-	-	-	S	-	-	-	RloB-like protein
MELMHNEA_02049	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MELMHNEA_02050	2.94e-118	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MELMHNEA_02051	4.81e-77	-	-	-	S	-	-	-	SIR2-like domain
MELMHNEA_02053	6.8e-50	-	-	-	S	-	-	-	Cytochrome B5
MELMHNEA_02054	1.12e-214	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
MELMHNEA_02055	3.04e-232	-	-	-	M	-	-	-	Glycosyl transferase family 8
MELMHNEA_02056	2.04e-183	-	-	-	M	-	-	-	Glycosyl transferase family 8
MELMHNEA_02057	1.95e-131	-	-	-	I	-	-	-	Acid phosphatase homologues
MELMHNEA_02058	2.25e-241	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MELMHNEA_02059	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MELMHNEA_02060	3.6e-106	-	-	-	C	-	-	-	Flavodoxin
MELMHNEA_02061	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MELMHNEA_02062	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MELMHNEA_02063	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MELMHNEA_02064	2.14e-154	-	-	-	C	-	-	-	nitroreductase
MELMHNEA_02065	1.76e-52	-	-	-	-	-	-	-	-
MELMHNEA_02066	1.96e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MELMHNEA_02067	1.52e-103	-	-	-	-	-	-	-	-
MELMHNEA_02068	6.89e-190	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MELMHNEA_02069	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
MELMHNEA_02070	7.44e-189	-	-	-	S	-	-	-	hydrolase
MELMHNEA_02071	1.85e-205	-	-	-	S	-	-	-	Phospholipase, patatin family
MELMHNEA_02072	2.22e-130	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MELMHNEA_02073	4.44e-174	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MELMHNEA_02074	2.9e-79	-	-	-	S	-	-	-	Enterocin A Immunity
MELMHNEA_02075	7.49e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MELMHNEA_02076	6.63e-174	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MELMHNEA_02077	1.01e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MELMHNEA_02078	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MELMHNEA_02079	6.36e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MELMHNEA_02080	7.3e-216	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MELMHNEA_02081	1.04e-208	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MELMHNEA_02082	3.66e-289	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MELMHNEA_02083	4.77e-294	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MELMHNEA_02084	6.18e-123	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MELMHNEA_02085	1.07e-93	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MELMHNEA_02086	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MELMHNEA_02087	8.69e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MELMHNEA_02088	1.52e-193	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MELMHNEA_02089	5.81e-253	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MELMHNEA_02090	6.85e-109	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MELMHNEA_02091	5.03e-256	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MELMHNEA_02092	1.77e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MELMHNEA_02093	9.22e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MELMHNEA_02094	5.09e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MELMHNEA_02095	8.01e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MELMHNEA_02096	2.19e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MELMHNEA_02097	4.53e-11	-	-	-	-	-	-	-	-
MELMHNEA_02098	1.02e-75	-	-	-	-	-	-	-	-
MELMHNEA_02099	6.84e-70	-	-	-	-	-	-	-	-
MELMHNEA_02101	2.97e-163	-	-	-	S	-	-	-	PAS domain
MELMHNEA_02102	3.2e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
MELMHNEA_02103	2.48e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MELMHNEA_02104	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MELMHNEA_02105	3.88e-52	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MELMHNEA_02106	5e-53	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MELMHNEA_02107	4.55e-221	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MELMHNEA_02108	2.16e-166	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MELMHNEA_02109	7.23e-50	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MELMHNEA_02110	2.05e-182	-	-	-	V	-	-	-	ABC transporter transmembrane region
MELMHNEA_02113	7.95e-250	ampC	-	-	V	-	-	-	Beta-lactamase
MELMHNEA_02114	1.33e-273	-	-	-	EGP	-	-	-	Major Facilitator
MELMHNEA_02115	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MELMHNEA_02116	5.3e-137	vanZ	-	-	V	-	-	-	VanZ like family
MELMHNEA_02117	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MELMHNEA_02118	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MELMHNEA_02119	4.96e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MELMHNEA_02120	9.01e-90	-	-	-	S	-	-	-	SdpI/YhfL protein family
MELMHNEA_02121	1.93e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MELMHNEA_02122	1.72e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MELMHNEA_02123	1.72e-127	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MELMHNEA_02124	1.47e-13	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MELMHNEA_02125	1.11e-09	-	-	-	T	ko:K07172	-	ko00000,ko02048	SpoVT / AbrB like domain
MELMHNEA_02126	5.62e-95	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MELMHNEA_02127	2.91e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MELMHNEA_02128	8.12e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MELMHNEA_02129	8.22e-38	-	-	-	-	-	-	-	-
MELMHNEA_02132	3.98e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MELMHNEA_02133	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MELMHNEA_02134	0.0	yycH	-	-	S	-	-	-	YycH protein
MELMHNEA_02135	7.44e-192	yycI	-	-	S	-	-	-	YycH protein
MELMHNEA_02136	1.19e-188	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MELMHNEA_02137	3.17e-224	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MELMHNEA_02138	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MELMHNEA_02139	6.2e-193	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
MELMHNEA_02140	6.64e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
MELMHNEA_02141	1.05e-176	-	-	-	F	-	-	-	Phosphorylase superfamily
MELMHNEA_02142	4.83e-114	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MELMHNEA_02143	2.92e-115	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MELMHNEA_02144	7.02e-36	-	-	-	-	-	-	-	-
MELMHNEA_02145	2.34e-105	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
MELMHNEA_02146	3.74e-125	-	-	-	-	-	-	-	-
MELMHNEA_02147	1.94e-96	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
MELMHNEA_02148	3.07e-124	-	-	-	-	-	-	-	-
MELMHNEA_02149	2.81e-200	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MELMHNEA_02150	3.86e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MELMHNEA_02151	1.1e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MELMHNEA_02152	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MELMHNEA_02153	1.51e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MELMHNEA_02154	2.84e-208	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MELMHNEA_02155	1.25e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MELMHNEA_02156	8.77e-173	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MELMHNEA_02157	3.69e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MELMHNEA_02158	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MELMHNEA_02159	2.13e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MELMHNEA_02160	2.76e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
MELMHNEA_02161	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MELMHNEA_02162	8.04e-190	-	-	-	S	-	-	-	hydrolase
MELMHNEA_02163	3.23e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
MELMHNEA_02164	6.7e-152	-	-	-	-	-	-	-	-
MELMHNEA_02165	3.07e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MELMHNEA_02166	1.25e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MELMHNEA_02167	8.39e-195	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MELMHNEA_02168	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MELMHNEA_02169	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MELMHNEA_02170	5.92e-235	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MELMHNEA_02171	0.0	-	-	-	E	-	-	-	Amino acid permease
MELMHNEA_02173	4.8e-38	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MELMHNEA_02174	7.83e-140	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
MELMHNEA_02175	3.31e-120	-	-	-	S	-	-	-	VanZ like family
MELMHNEA_02176	5.65e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MELMHNEA_02177	1.58e-199	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MELMHNEA_02178	1.72e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MELMHNEA_02179	7.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MELMHNEA_02180	8.52e-93	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
MELMHNEA_02181	1.96e-54	-	-	-	-	-	-	-	-
MELMHNEA_02182	1.31e-98	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MELMHNEA_02183	3.69e-30	-	-	-	-	-	-	-	-
MELMHNEA_02184	4.37e-241	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MELMHNEA_02185	1.07e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MELMHNEA_02187	3.73e-194	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MELMHNEA_02189	6.66e-31	-	-	-	K	-	-	-	Helix-turn-helix domain
MELMHNEA_02190	6.74e-30	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
MELMHNEA_02191	2.14e-40	-	-	-	K	-	-	-	Helix-turn-helix domain
MELMHNEA_02193	2.13e-14	-	-	-	S	-	-	-	Arc-like DNA binding domain
MELMHNEA_02195	3.94e-18	-	-	-	-	-	-	-	-
MELMHNEA_02196	3.16e-34	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
MELMHNEA_02203	2.59e-10	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MELMHNEA_02209	2.63e-25	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MELMHNEA_02211	6.47e-10	-	-	-	M	-	-	-	oxidoreductase activity
MELMHNEA_02212	3.24e-13	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_02217	1.14e-163	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
MELMHNEA_02221	3.25e-194	-	-	-	S	-	-	-	COG0433 Predicted ATPase
MELMHNEA_02222	2.23e-24	lysM	-	-	M	-	-	-	LysM domain
MELMHNEA_02231	2.64e-34	-	-	-	L	-	-	-	four-way junction helicase activity
MELMHNEA_02232	4.2e-22	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MELMHNEA_02233	3.71e-142	-	-	-	S	-	-	-	Fic/DOC family
MELMHNEA_02234	7.21e-54	-	-	-	E	-	-	-	Pfam:DUF955
MELMHNEA_02235	7.21e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
MELMHNEA_02236	1.33e-22	-	-	-	S	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MELMHNEA_02237	3.24e-112	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
MELMHNEA_02238	3.06e-85	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
MELMHNEA_02239	1.5e-150	-	-	-	S	-	-	-	F420-0:Gamma-glutamyl ligase
MELMHNEA_02240	1.83e-103	-	-	-	S	-	-	-	AAA domain
MELMHNEA_02241	9.82e-80	-	-	-	F	-	-	-	NUDIX domain
MELMHNEA_02242	5.26e-85	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MELMHNEA_02243	1.21e-119	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MELMHNEA_02244	1.15e-64	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MELMHNEA_02245	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MELMHNEA_02246	5.46e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MELMHNEA_02247	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MELMHNEA_02248	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MELMHNEA_02249	9.53e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
MELMHNEA_02251	0.0	-	-	-	-	-	-	-	-
MELMHNEA_02252	0.0	ycaM	-	-	E	-	-	-	amino acid
MELMHNEA_02253	1.43e-178	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MELMHNEA_02254	7.65e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MELMHNEA_02255	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MELMHNEA_02256	4.64e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MELMHNEA_02257	2.32e-313	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MELMHNEA_02258	0.0	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
MELMHNEA_02259	9.18e-202	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MELMHNEA_02260	5.5e-155	-	-	-	-	-	-	-	-
MELMHNEA_02261	5.05e-184	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MELMHNEA_02262	9.79e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
MELMHNEA_02265	6.1e-186	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_02266	2.55e-65	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_02267	8.1e-87	-	-	-	S	-	-	-	Domain of unknown function DUF1828
MELMHNEA_02268	7.91e-14	-	-	-	-	-	-	-	-
MELMHNEA_02269	2.93e-67	-	-	-	-	-	-	-	-
MELMHNEA_02270	1.05e-226	citR	-	-	K	-	-	-	Putative sugar-binding domain
MELMHNEA_02271	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
MELMHNEA_02273	1.13e-45	-	-	-	-	-	-	-	-
MELMHNEA_02274	7.7e-21	-	-	-	-	-	-	-	-
MELMHNEA_02275	5.12e-242	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MELMHNEA_02276	1.84e-263	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
MELMHNEA_02279	6.69e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MELMHNEA_02280	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MELMHNEA_02281	1.23e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MELMHNEA_02282	3.42e-30	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
MELMHNEA_02283	4.19e-192	-	-	-	I	-	-	-	Acyl-transferase
MELMHNEA_02284	1.2e-199	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
MELMHNEA_02285	4.53e-209	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MELMHNEA_02286	3.09e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MELMHNEA_02287	8.08e-160	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MELMHNEA_02288	2.57e-108	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MELMHNEA_02289	9.91e-150	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MELMHNEA_02290	3.53e-63	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MELMHNEA_02291	1.55e-82	-	-	-	M	-	-	-	SIS domain
MELMHNEA_02292	8.46e-98	-	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MELMHNEA_02293	1.38e-46	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MELMHNEA_02294	3.94e-254	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MELMHNEA_02295	3.05e-53	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MELMHNEA_02296	2.39e-85	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MELMHNEA_02297	2.76e-188	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MELMHNEA_02298	1.45e-43	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MELMHNEA_02299	4.19e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MELMHNEA_02300	1.05e-289	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MELMHNEA_02301	6.72e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
MELMHNEA_02302	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MELMHNEA_02303	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MELMHNEA_02304	1.2e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MELMHNEA_02306	1.44e-07	-	-	-	S	-	-	-	YSIRK type signal peptide
MELMHNEA_02307	9.62e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MELMHNEA_02308	1.07e-179	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MELMHNEA_02309	3.16e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MELMHNEA_02310	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MELMHNEA_02311	1.65e-205	yvgN	-	-	C	-	-	-	Aldo keto reductase
MELMHNEA_02312	7.2e-202	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MELMHNEA_02313	7.75e-170	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MELMHNEA_02314	3.35e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MELMHNEA_02315	4.76e-168	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MELMHNEA_02316	8.64e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MELMHNEA_02317	1.59e-315	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MELMHNEA_02318	2.55e-26	-	-	-	-	-	-	-	-
MELMHNEA_02319	3.93e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MELMHNEA_02320	4.4e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
MELMHNEA_02321	1.82e-135	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_02322	5.14e-264	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MELMHNEA_02323	3.82e-149	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MELMHNEA_02324	1.65e-44	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MELMHNEA_02325	8.6e-128	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
MELMHNEA_02326	2.1e-144	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MELMHNEA_02327	1.14e-05	-	-	-	M	-	-	-	Rib/alpha-like repeat
MELMHNEA_02328	7.44e-129	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MELMHNEA_02329	1.01e-33	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MELMHNEA_02330	5.34e-77	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
MELMHNEA_02331	1.1e-60	-	-	-	-	-	-	-	-
MELMHNEA_02332	6.21e-60	-	-	-	V	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
MELMHNEA_02336	1.71e-172	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
MELMHNEA_02337	8.61e-54	-	-	-	S	-	-	-	Enterocin A Immunity
MELMHNEA_02338	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MELMHNEA_02339	3.81e-275	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MELMHNEA_02340	1.39e-160	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MELMHNEA_02341	3.75e-79	-	-	-	-	-	-	-	-
MELMHNEA_02342	6.04e-26	-	-	-	-	-	-	-	-
MELMHNEA_02343	1.9e-126	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MELMHNEA_02344	2.52e-76	-	-	-	-	-	-	-	-
MELMHNEA_02345	0.0	-	-	-	S	-	-	-	ABC transporter
MELMHNEA_02346	7.35e-174	-	-	-	S	-	-	-	Putative threonine/serine exporter
MELMHNEA_02347	7.36e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MELMHNEA_02348	1.58e-143	-	-	-	S	-	-	-	Peptidase_C39 like family
MELMHNEA_02349	1.16e-101	-	-	-	-	-	-	-	-
MELMHNEA_02350	1.96e-226	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MELMHNEA_02351	4.75e-101	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MELMHNEA_02352	6.96e-286	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MELMHNEA_02353	8.77e-144	-	-	-	-	-	-	-	-
MELMHNEA_02354	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
MELMHNEA_02355	4.52e-56	-	-	-	-	-	-	-	-
MELMHNEA_02356	2.11e-115	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
MELMHNEA_02357	4.39e-116	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MELMHNEA_02358	1.28e-174	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MELMHNEA_02359	1.73e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MELMHNEA_02360	3.01e-54	-	-	-	-	-	-	-	-
MELMHNEA_02361	1.26e-223	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MELMHNEA_02362	1.3e-282	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MELMHNEA_02366	2.75e-86	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MELMHNEA_02367	2.58e-45	-	-	-	-	-	-	-	-
MELMHNEA_02368	7.14e-91	-	-	-	EGP	-	-	-	Major Facilitator
MELMHNEA_02369	3.73e-300	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MELMHNEA_02370	1.29e-115	-	-	-	EGP	-	-	-	Major Facilitator
MELMHNEA_02371	5.53e-154	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_02373	2.85e-54	-	-	-	-	-	-	-	-
MELMHNEA_02374	3.6e-101	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MELMHNEA_02376	4.56e-191	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MELMHNEA_02377	1.2e-89	-	-	-	S	-	-	-	SLAP domain
MELMHNEA_02378	7.04e-91	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MELMHNEA_02379	4.3e-175	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MELMHNEA_02380	3.85e-180	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MELMHNEA_02381	1.31e-231	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MELMHNEA_02382	5.61e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MELMHNEA_02383	5.18e-109	-	-	-	-	-	-	-	-
MELMHNEA_02384	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MELMHNEA_02385	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MELMHNEA_02386	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MELMHNEA_02387	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MELMHNEA_02388	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MELMHNEA_02389	1.69e-132	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MELMHNEA_02390	1.8e-291	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MELMHNEA_02391	1.62e-277	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
MELMHNEA_02392	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MELMHNEA_02393	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MELMHNEA_02394	3.8e-92	-	-	-	-	-	-	-	-
MELMHNEA_02395	3.75e-48	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MELMHNEA_02397	4.53e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MELMHNEA_02398	3.61e-60	-	-	-	-	-	-	-	-
MELMHNEA_02399	5.23e-31	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
MELMHNEA_02400	2.72e-05	-	-	-	M	ko:K11021	-	ko00000,ko02042	COG3209 Rhs family protein
MELMHNEA_02402	8.25e-16	-	-	-	S	-	-	-	Protein conserved in bacteria
MELMHNEA_02403	4.26e-27	-	-	-	E	-	-	-	Pfam:DUF955
MELMHNEA_02405	2.21e-155	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MELMHNEA_02407	5.43e-28	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MELMHNEA_02409	2.78e-45	-	-	-	-	-	-	-	-
MELMHNEA_02410	6.28e-87	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
MELMHNEA_02412	5.44e-299	-	-	-	V	-	-	-	N-6 DNA Methylase
MELMHNEA_02413	1.4e-104	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MELMHNEA_02414	6.8e-48	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MELMHNEA_02415	3.03e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MELMHNEA_02417	1.69e-125	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	VirC1 protein
MELMHNEA_02418	5.55e-22	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
MELMHNEA_02420	1.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MELMHNEA_02421	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MELMHNEA_02422	8e-254	flp	-	-	V	-	-	-	Beta-lactamase
MELMHNEA_02423	7.58e-291	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MELMHNEA_02424	1.64e-65	-	-	-	-	-	-	-	-
MELMHNEA_02425	4.83e-144	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MELMHNEA_02426	3.63e-83	-	-	-	K	-	-	-	transcriptional regulator
MELMHNEA_02428	3.93e-219	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MELMHNEA_02429	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MELMHNEA_02430	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MELMHNEA_02431	5.42e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MELMHNEA_02432	2.54e-267	camS	-	-	S	-	-	-	sex pheromone
MELMHNEA_02433	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MELMHNEA_02434	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MELMHNEA_02435	3.29e-127	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MELMHNEA_02437	2.24e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MELMHNEA_02438	5.48e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MELMHNEA_02439	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MELMHNEA_02440	9.16e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MELMHNEA_02441	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MELMHNEA_02442	1.91e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MELMHNEA_02443	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MELMHNEA_02444	2.94e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
MELMHNEA_02445	2.13e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MELMHNEA_02446	1.48e-84	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MELMHNEA_02447	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
MELMHNEA_02448	2.75e-43	-	-	-	G	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MELMHNEA_02449	1.34e-22	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MELMHNEA_02450	6.94e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MELMHNEA_02451	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MELMHNEA_02452	1.08e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MELMHNEA_02453	3.51e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MELMHNEA_02454	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MELMHNEA_02455	1.37e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MELMHNEA_02456	4.11e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MELMHNEA_02457	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MELMHNEA_02458	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MELMHNEA_02459	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MELMHNEA_02460	9e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MELMHNEA_02461	7.4e-159	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MELMHNEA_02462	3.76e-18	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MELMHNEA_02463	7.51e-16	-	-	-	L	-	-	-	Transposase
MELMHNEA_02464	1.01e-22	-	-	-	L	-	-	-	Transposase
MELMHNEA_02465	1.17e-196	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MELMHNEA_02467	5.85e-86	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
MELMHNEA_02468	1.52e-157	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MELMHNEA_02469	1.78e-163	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
MELMHNEA_02470	2.85e-115	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
MELMHNEA_02471	1.18e-42	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MELMHNEA_02472	6.58e-293	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MELMHNEA_02473	4.93e-80	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MELMHNEA_02474	6.33e-221	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
MELMHNEA_02476	3.68e-176	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MELMHNEA_02477	3.05e-110	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MELMHNEA_02478	3.61e-288	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MELMHNEA_02479	1.91e-103	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MELMHNEA_02480	1.32e-114	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MELMHNEA_02481	1.16e-13	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MELMHNEA_02482	2.45e-95	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MELMHNEA_02483	8.66e-85	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MELMHNEA_02484	1.03e-262	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MELMHNEA_02485	3.25e-315	-	-	-	M	-	-	-	Glycosyl transferase
MELMHNEA_02487	9.39e-195	-	-	-	-	-	-	-	-