ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KHBLGEKB_00001 2.07e-141 - - - - - - - -
KHBLGEKB_00002 1.83e-244 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
KHBLGEKB_00003 4.33e-281 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
KHBLGEKB_00004 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
KHBLGEKB_00005 1.27e-118 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHBLGEKB_00006 4.1e-39 - - - J - - - Acetyltransferase (GNAT) domain
KHBLGEKB_00007 2.63e-121 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHBLGEKB_00008 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
KHBLGEKB_00009 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHBLGEKB_00010 1.45e-312 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
KHBLGEKB_00011 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHBLGEKB_00012 3.19e-205 - - - K - - - Helix-turn-helix domain, rpiR family
KHBLGEKB_00013 2.99e-289 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
KHBLGEKB_00014 2.12e-59 - - - S ko:K06990 - ko00000,ko04812 Memo-like protein
KHBLGEKB_00016 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHBLGEKB_00017 5.85e-228 yogA - - C - - - Zinc-binding dehydrogenase
KHBLGEKB_00018 5.14e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHBLGEKB_00019 5.14e-291 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHBLGEKB_00020 8.27e-96 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KHBLGEKB_00021 5.38e-61 - - - - - - - -
KHBLGEKB_00022 9.36e-66 - - - S - - - TIGRFAM TIGR03943 family protein
KHBLGEKB_00023 1.7e-84 - - - S - - - TIGRFAM TIGR03943 family protein
KHBLGEKB_00024 2.92e-257 - - - S ko:K07089 - ko00000 Predicted permease
KHBLGEKB_00025 6.34e-33 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
KHBLGEKB_00026 3.05e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
KHBLGEKB_00027 1.79e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KHBLGEKB_00028 4.85e-65 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHBLGEKB_00029 4.39e-62 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
KHBLGEKB_00030 1.82e-178 - - - S - - - cobalamin synthesis protein
KHBLGEKB_00031 5.31e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
KHBLGEKB_00033 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
KHBLGEKB_00034 0.0 - - - S - - - Putative esterase
KHBLGEKB_00035 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
KHBLGEKB_00036 5.35e-307 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KHBLGEKB_00037 1.21e-244 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KHBLGEKB_00038 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHBLGEKB_00039 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
KHBLGEKB_00040 9.82e-45 - - - - - - - -
KHBLGEKB_00041 1.64e-90 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHBLGEKB_00042 4.51e-44 - - - K - - - DNA-binding transcription factor activity
KHBLGEKB_00043 4.32e-132 nnrE - - L - - - Uracil DNA glycosylase superfamily
KHBLGEKB_00044 2.2e-140 - - - S - - - Protein of unknown function (DUF4230)
KHBLGEKB_00045 5.92e-142 - - - - - - - -
KHBLGEKB_00046 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
KHBLGEKB_00047 2.05e-177 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KHBLGEKB_00048 1.91e-298 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KHBLGEKB_00049 0.0 - - - M - - - Parallel beta-helix repeats
KHBLGEKB_00050 4.41e-291 - - - M - - - Glycosyl transferase 4-like domain
KHBLGEKB_00051 5.42e-255 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
KHBLGEKB_00053 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHBLGEKB_00054 9.4e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KHBLGEKB_00055 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHBLGEKB_00056 5.83e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHBLGEKB_00057 0.0 - - - S - - - Esterase-like activity of phytase
KHBLGEKB_00058 1.68e-251 - - - EGP - - - Transmembrane secretion effector
KHBLGEKB_00060 3.8e-135 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHBLGEKB_00061 2.04e-150 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHBLGEKB_00062 9.86e-304 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
KHBLGEKB_00063 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
KHBLGEKB_00064 0.0 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KHBLGEKB_00065 0.0 - - - S - - - Protein of unknown function DUF262
KHBLGEKB_00066 6.09e-152 - - - K - - - helix_turn_helix, Lux Regulon
KHBLGEKB_00067 0.0 - - - T - - - Histidine kinase
KHBLGEKB_00068 2.17e-151 - - - S - - - Domain of unknown function (DUF5067)
KHBLGEKB_00069 8.71e-176 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
KHBLGEKB_00070 1.83e-217 - - - EG - - - EamA-like transporter family
KHBLGEKB_00071 1.42e-156 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
KHBLGEKB_00072 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHBLGEKB_00073 2.09e-234 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHBLGEKB_00074 3.82e-176 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KHBLGEKB_00075 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
KHBLGEKB_00076 6.37e-160 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHBLGEKB_00077 1.14e-124 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KHBLGEKB_00078 2.53e-106 - - - K - - - Helix-turn-helix XRE-family like proteins
KHBLGEKB_00079 1.96e-53 - - - S - - - Protein of unknown function (DUF3046)
KHBLGEKB_00080 7.71e-276 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHBLGEKB_00081 1.39e-95 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
KHBLGEKB_00083 3.68e-152 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHBLGEKB_00084 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHBLGEKB_00086 1.86e-245 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KHBLGEKB_00087 3.08e-140 - - - - - - - -
KHBLGEKB_00088 3.55e-172 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
KHBLGEKB_00089 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
KHBLGEKB_00090 2.13e-255 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KHBLGEKB_00091 1.98e-157 - - - - - - - -
KHBLGEKB_00092 3.09e-252 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHBLGEKB_00093 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
KHBLGEKB_00094 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
KHBLGEKB_00095 2.83e-22 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
KHBLGEKB_00096 1.65e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KHBLGEKB_00097 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
KHBLGEKB_00098 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
KHBLGEKB_00099 3.3e-300 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
KHBLGEKB_00100 7.18e-236 - - - S - - - Protein of unknown function (DUF3071)
KHBLGEKB_00101 2.45e-63 - - - S - - - Domain of unknown function (DUF4193)
KHBLGEKB_00102 5.02e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KHBLGEKB_00103 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHBLGEKB_00104 2.33e-39 - - - - - - - -
KHBLGEKB_00106 9.23e-266 - - - E - - - Belongs to the peptidase S1B family
KHBLGEKB_00107 1.78e-89 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
KHBLGEKB_00108 9.55e-66 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KHBLGEKB_00109 3.42e-134 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHBLGEKB_00110 2.76e-212 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHBLGEKB_00111 1.73e-107 - - - P - - - ABC-type metal ion transport system permease component
KHBLGEKB_00112 2e-285 - - - S - - - Peptidase dimerisation domain
KHBLGEKB_00113 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHBLGEKB_00114 3.51e-52 - - - - - - - -
KHBLGEKB_00115 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
KHBLGEKB_00116 3.65e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHBLGEKB_00117 1.94e-146 - - - S - - - Protein of unknown function (DUF3000)
KHBLGEKB_00118 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
KHBLGEKB_00119 5.17e-307 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KHBLGEKB_00120 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
KHBLGEKB_00121 4.05e-147 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHBLGEKB_00122 9.32e-164 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHBLGEKB_00123 1.23e-311 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHBLGEKB_00126 4.28e-297 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
KHBLGEKB_00127 1.67e-290 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KHBLGEKB_00128 7.06e-221 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KHBLGEKB_00129 1.01e-150 safC - - S - - - O-methyltransferase
KHBLGEKB_00130 3.57e-235 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
KHBLGEKB_00131 2.23e-93 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
KHBLGEKB_00132 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
KHBLGEKB_00133 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
KHBLGEKB_00134 1.52e-75 - - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
KHBLGEKB_00135 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
KHBLGEKB_00136 3.62e-212 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
KHBLGEKB_00137 2.83e-201 - - - S - - - Putative ABC-transporter type IV
KHBLGEKB_00138 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
KHBLGEKB_00139 1.63e-209 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHBLGEKB_00140 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KHBLGEKB_00141 0.0 - - - I - - - PAP2 superfamily
KHBLGEKB_00142 4.15e-171 - - - K - - - helix_turn_helix, Lux Regulon
KHBLGEKB_00143 0.0 - - - T - - - Histidine kinase
KHBLGEKB_00144 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
KHBLGEKB_00145 1.74e-182 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHBLGEKB_00146 2.32e-210 iaaA 3.4.19.5 - E ko:K13051 - ko00000,ko01000,ko01002 Asparaginase
KHBLGEKB_00147 1.28e-187 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
KHBLGEKB_00148 3.45e-240 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
KHBLGEKB_00149 1.1e-235 acoB 1.2.4.1, 1.2.4.4 - C ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
KHBLGEKB_00150 2.72e-261 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHBLGEKB_00151 9.77e-123 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHBLGEKB_00152 1.27e-292 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
KHBLGEKB_00153 1.02e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KHBLGEKB_00154 1.44e-71 - 2.1.1.113, 2.1.1.72 - L ko:K00571,ko:K00590 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
KHBLGEKB_00155 3.61e-243 mod 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 PFAM DNA methylase
KHBLGEKB_00156 3.42e-298 - 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme res subunit
KHBLGEKB_00157 1.34e-75 - - - J - - - tRNA cytidylyltransferase activity
KHBLGEKB_00158 1.3e-10 rep 3.6.4.12 - L ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction
KHBLGEKB_00161 5.2e-63 - - - - - - - -
KHBLGEKB_00162 8.04e-313 - - - K - - - Fic/DOC family
KHBLGEKB_00163 2.73e-162 - - - E - - - Psort location Cytoplasmic, score 8.87
KHBLGEKB_00164 5.59e-78 yccF - - S - - - Inner membrane component domain
KHBLGEKB_00165 3.83e-202 - - - J - - - Methyltransferase domain
KHBLGEKB_00166 6.29e-103 - - - S - - - Cupin 2, conserved barrel domain protein
KHBLGEKB_00167 0.0 - - - KLT - - - Protein tyrosine kinase
KHBLGEKB_00168 6.04e-103 - - - K - - - Psort location Cytoplasmic, score
KHBLGEKB_00170 1.1e-30 - - - - - - - -
KHBLGEKB_00171 1.14e-261 - - - S - - - Short C-terminal domain
KHBLGEKB_00172 1.1e-112 - - - S - - - Helix-turn-helix
KHBLGEKB_00173 7.03e-86 - - - S - - - Zincin-like metallopeptidase
KHBLGEKB_00174 1.66e-46 - - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KHBLGEKB_00175 3.2e-48 - - - - - - - -
KHBLGEKB_00176 1.5e-96 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KHBLGEKB_00177 2.14e-160 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
KHBLGEKB_00178 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
KHBLGEKB_00180 0.0 - - - M - - - Glycosyltransferase like family 2
KHBLGEKB_00181 5.28e-152 - - - E - - - haloacid dehalogenase-like hydrolase
KHBLGEKB_00182 8.63e-185 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
KHBLGEKB_00183 4.33e-238 - - - S - - - Conserved hypothetical protein 698
KHBLGEKB_00184 1.72e-204 - - - G - - - Phosphoglycerate mutase family
KHBLGEKB_00185 2.75e-304 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
KHBLGEKB_00186 1.84e-98 - - - K - - - AraC-like ligand binding domain
KHBLGEKB_00188 7.28e-71 - - - IQ - - - oxidoreductase activity
KHBLGEKB_00189 9.25e-176 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
KHBLGEKB_00190 9.68e-173 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_00191 4.53e-205 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHBLGEKB_00192 4.32e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHBLGEKB_00193 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
KHBLGEKB_00194 1.23e-133 - - - - - - - -
KHBLGEKB_00195 4.51e-261 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KHBLGEKB_00196 1.82e-275 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KHBLGEKB_00197 4.12e-227 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KHBLGEKB_00198 4.83e-314 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
KHBLGEKB_00199 2.51e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHBLGEKB_00200 1.29e-112 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KHBLGEKB_00201 5.96e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KHBLGEKB_00202 5.13e-61 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
KHBLGEKB_00203 8.68e-229 - - - L - - - Phage integrase family
KHBLGEKB_00204 1.41e-204 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Phosphotransferase enzyme family
KHBLGEKB_00205 9.62e-218 - - - L - - - Transposase and inactivated derivatives IS30 family
KHBLGEKB_00206 1.82e-253 - - - L - - - Transposase and inactivated derivatives IS30 family
KHBLGEKB_00208 1.95e-128 - - - - - - - -
KHBLGEKB_00209 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
KHBLGEKB_00210 1.62e-204 tnp3521a2 - - L - - - Integrase core domain
KHBLGEKB_00211 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KHBLGEKB_00212 2.66e-76 yccF - - S - - - Inner membrane component domain
KHBLGEKB_00213 1.9e-17 - - - - - - - -
KHBLGEKB_00214 6.68e-94 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
KHBLGEKB_00216 9.43e-25 - - - E - - - Domain of unknown function (DUF5011)
KHBLGEKB_00217 9.21e-52 - - - S - - - Parallel beta-helix repeats
KHBLGEKB_00219 2.34e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KHBLGEKB_00220 1.51e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHBLGEKB_00221 1.12e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
KHBLGEKB_00222 6.47e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KHBLGEKB_00223 1.51e-227 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
KHBLGEKB_00224 6.29e-55 - - - - - - - -
KHBLGEKB_00225 2.85e-54 - - - - - - - -
KHBLGEKB_00226 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KHBLGEKB_00227 1.26e-242 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHBLGEKB_00228 0.0 - 3.2.1.97 GH101 G ko:K17624 - ko00000,ko01000 Glycosyl hydrolase 101 beta sandwich domain
KHBLGEKB_00229 1.73e-253 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
KHBLGEKB_00230 1.42e-278 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KHBLGEKB_00231 1.38e-227 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
KHBLGEKB_00232 1.27e-221 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
KHBLGEKB_00233 6.4e-164 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KHBLGEKB_00234 4.95e-44 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KHBLGEKB_00236 2.89e-294 aspC 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
KHBLGEKB_00237 6.1e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHBLGEKB_00238 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHBLGEKB_00239 6.29e-274 - - - K - - - Psort location Cytoplasmic, score
KHBLGEKB_00240 2.12e-53 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
KHBLGEKB_00241 1.44e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KHBLGEKB_00242 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
KHBLGEKB_00243 2e-304 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
KHBLGEKB_00244 9.55e-215 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
KHBLGEKB_00245 0.0 - - - V - - - Efflux ABC transporter, permease protein
KHBLGEKB_00246 1.59e-210 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_00247 2.73e-76 - - - - - - - -
KHBLGEKB_00248 5.49e-85 - - - - - - - -
KHBLGEKB_00249 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
KHBLGEKB_00250 5.51e-239 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KHBLGEKB_00251 1.79e-304 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
KHBLGEKB_00252 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KHBLGEKB_00253 5.94e-107 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHBLGEKB_00254 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KHBLGEKB_00255 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KHBLGEKB_00256 3.93e-230 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
KHBLGEKB_00257 2.69e-82 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
KHBLGEKB_00258 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
KHBLGEKB_00260 1.03e-196 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
KHBLGEKB_00261 5.92e-26 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
KHBLGEKB_00262 6.82e-25 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 carboxylic acid catabolic process
KHBLGEKB_00263 4e-235 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
KHBLGEKB_00265 2.31e-115 - - - L - - - Transposase, Mutator family
KHBLGEKB_00266 1.35e-170 - - - L - - - IstB-like ATP binding protein
KHBLGEKB_00267 4.67e-300 - - - L - - - PFAM Integrase catalytic
KHBLGEKB_00268 2.88e-54 - - - L - - - Transposase, Mutator family
KHBLGEKB_00269 3.17e-179 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
KHBLGEKB_00270 1.02e-89 - - - - - - - -
KHBLGEKB_00271 1.05e-286 - - - S - - - MvaI/BcnI restriction endonuclease family
KHBLGEKB_00272 6.05e-288 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
KHBLGEKB_00273 1.1e-29 - - - - - - - -
KHBLGEKB_00274 2.34e-131 - - - M - - - Glycosyl hydrolases family 25
KHBLGEKB_00276 8.18e-49 - - - - - - - -
KHBLGEKB_00277 3.88e-141 - - - - - - - -
KHBLGEKB_00278 4.87e-280 - - - S - - - Phage minor structural protein
KHBLGEKB_00279 3.45e-127 - - - - - - - -
KHBLGEKB_00280 0.0 - - - S - - - phage tail tape measure protein
KHBLGEKB_00281 2.4e-55 - - - - - - - -
KHBLGEKB_00282 7.12e-39 - - - - - - - -
KHBLGEKB_00283 5.14e-97 - - - N - - - domain, Protein
KHBLGEKB_00284 6.92e-43 - - - - - - - -
KHBLGEKB_00285 1.78e-67 - - - S - - - Phage protein Gp19/Gp15/Gp42
KHBLGEKB_00286 1.64e-37 - - - - - - - -
KHBLGEKB_00287 2.68e-172 - - - S - - - Phage capsid family
KHBLGEKB_00288 3.86e-41 - - - - - - - -
KHBLGEKB_00289 5.57e-72 - - - - - - - -
KHBLGEKB_00290 1.05e-149 - - - S - - - Phage portal protein, SPP1 Gp6-like
KHBLGEKB_00291 3.14e-50 - - - S - - - Phage portal protein, SPP1 Gp6-like
KHBLGEKB_00292 1.93e-276 - - - S - - - Terminase
KHBLGEKB_00293 1.81e-20 - - - - - - - -
KHBLGEKB_00296 4.05e-17 - - - V - - - HNH nucleases
KHBLGEKB_00297 9.92e-280 - - - L - - - Phage integrase family
KHBLGEKB_00298 7.49e-09 - - - - - - - -
KHBLGEKB_00299 3.98e-65 - - - K - - - Helix-turn-helix XRE-family like proteins
KHBLGEKB_00301 9.04e-36 - - - - - - - -
KHBLGEKB_00302 1.17e-65 - - - - - - - -
KHBLGEKB_00303 1.36e-23 - - - - - - - -
KHBLGEKB_00304 2.92e-48 - - - - - - - -
KHBLGEKB_00305 5.43e-75 - - - - - - - -
KHBLGEKB_00306 1.14e-68 - - - - - - - -
KHBLGEKB_00307 1.99e-80 - - - L - - - single-stranded DNA binding
KHBLGEKB_00308 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
KHBLGEKB_00309 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KHBLGEKB_00310 6.52e-289 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KHBLGEKB_00311 2.22e-231 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_00312 1.06e-57 pacL 3.6.3.8, 3.6.3.9 - P ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 ATPase, P-type transporting, HAD superfamily, subfamily IC
KHBLGEKB_00313 2.93e-298 - - - T - - - Histidine kinase
KHBLGEKB_00314 2.19e-153 - - - K - - - helix_turn_helix, Lux Regulon
KHBLGEKB_00315 4.91e-150 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
KHBLGEKB_00316 7.55e-243 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
KHBLGEKB_00317 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KHBLGEKB_00318 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KHBLGEKB_00319 1.53e-33 - - - - - - - -
KHBLGEKB_00320 1.48e-232 - - - - - - - -
KHBLGEKB_00321 5.06e-46 - - - L - - - Transposase
KHBLGEKB_00322 2.88e-60 - - - L - - - Integrase core domain
KHBLGEKB_00324 4.36e-237 - - - S - - - Protein of unknown function DUF262
KHBLGEKB_00325 2.29e-152 - - - S - - - Protein of unknown function (DUF3800)
KHBLGEKB_00326 1.76e-18 - - - - - - - -
KHBLGEKB_00327 1.46e-37 - - - - - - - -
KHBLGEKB_00328 7.78e-59 - - - S - - - Protein of unknown function (DUF1294)
KHBLGEKB_00329 3.84e-68 - - - S - - - Protein of unknown function (DUF1294)
KHBLGEKB_00332 2.81e-157 - - - - - - - -
KHBLGEKB_00333 3.97e-116 - - - S - - - Domain of unknown function (DUF1846)
KHBLGEKB_00334 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
KHBLGEKB_00335 1.39e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHBLGEKB_00336 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KHBLGEKB_00337 1.07e-143 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
KHBLGEKB_00338 6.7e-93 - - - L - - - Phage integrase family
KHBLGEKB_00339 2.57e-67 - - - L - - - Phage integrase family
KHBLGEKB_00341 8.41e-280 - - - - - - - -
KHBLGEKB_00342 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
KHBLGEKB_00343 5.78e-162 - - - L - - - NUDIX domain
KHBLGEKB_00344 5.17e-219 - - - L - - - NIF3 (NGG1p interacting factor 3)
KHBLGEKB_00345 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHBLGEKB_00346 5.44e-161 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
KHBLGEKB_00348 1.71e-142 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
KHBLGEKB_00349 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
KHBLGEKB_00350 1.68e-229 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
KHBLGEKB_00351 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KHBLGEKB_00352 4.53e-139 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHBLGEKB_00353 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KHBLGEKB_00354 1.41e-209 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHBLGEKB_00355 1.55e-232 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
KHBLGEKB_00356 2.33e-209 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_00357 2.15e-177 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
KHBLGEKB_00358 3.64e-108 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KHBLGEKB_00359 1.99e-131 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
KHBLGEKB_00360 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KHBLGEKB_00361 9.32e-164 cseB - - T - - - Response regulator receiver domain protein
KHBLGEKB_00362 2.06e-259 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHBLGEKB_00363 3.2e-93 umuD - - KT ko:K03503 - ko00000,ko01000,ko01002,ko03400 Peptidase S24-like
KHBLGEKB_00364 3.82e-167 pyrE_1 - - S - - - Phosphoribosyl transferase domain
KHBLGEKB_00365 2.33e-200 - - - T - - - Eukaryotic phosphomannomutase
KHBLGEKB_00366 1.05e-85 - - - S - - - Zincin-like metallopeptidase
KHBLGEKB_00367 0.0 - - - - - - - -
KHBLGEKB_00368 0.0 - - - S - - - Glycosyl transferase, family 2
KHBLGEKB_00369 2.82e-72 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KHBLGEKB_00370 0.0 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
KHBLGEKB_00371 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
KHBLGEKB_00372 6.69e-61 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KHBLGEKB_00373 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHBLGEKB_00374 5.58e-193 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
KHBLGEKB_00375 2.65e-139 - - - - - - - -
KHBLGEKB_00376 1.67e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHBLGEKB_00377 8.53e-95 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
KHBLGEKB_00378 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
KHBLGEKB_00379 4.4e-126 - - - - - - - -
KHBLGEKB_00381 2.41e-233 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
KHBLGEKB_00382 3.62e-137 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
KHBLGEKB_00383 1.03e-131 - - - D - - - Septum formation initiator
KHBLGEKB_00384 7.41e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHBLGEKB_00385 2.04e-194 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 - E ko:K00826,ko:K01665,ko:K02619,ko:K03342 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 branched-chain-amino-acid transaminase activity
KHBLGEKB_00386 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 - EH ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000,ko01007 chorismate binding enzyme
KHBLGEKB_00387 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHBLGEKB_00388 3.48e-146 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KHBLGEKB_00389 1.45e-123 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
KHBLGEKB_00390 1.97e-186 rfbB2 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KHBLGEKB_00391 1.4e-193 - - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
KHBLGEKB_00392 1.21e-252 - - - GM - - - GDP-mannose 4,6 dehydratase
KHBLGEKB_00393 1.82e-165 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KHBLGEKB_00395 3.3e-281 - - - I ko:K13663 - ko00000,ko01000 transferase activity, transferring acyl groups other than amino-acyl groups
KHBLGEKB_00396 0.0 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHBLGEKB_00397 5.02e-264 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHBLGEKB_00398 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
KHBLGEKB_00399 6.64e-296 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
KHBLGEKB_00400 5.63e-253 - - - - - - - -
KHBLGEKB_00401 2.07e-195 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_00402 3.07e-244 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
KHBLGEKB_00403 0.0 argE - - E - - - Peptidase dimerisation domain
KHBLGEKB_00404 2.94e-134 - - - S - - - Protein of unknown function (DUF3043)
KHBLGEKB_00405 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHBLGEKB_00406 2.47e-181 - - - S - - - Domain of unknown function (DUF4191)
KHBLGEKB_00407 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KHBLGEKB_00408 1.34e-24 - - - - - - - -
KHBLGEKB_00410 8.73e-21 - - - - - - - -
KHBLGEKB_00414 2.02e-203 - - - S - - - Protein conserved in bacteria
KHBLGEKB_00415 8.24e-270 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KHBLGEKB_00416 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHBLGEKB_00417 0.0 - - - S - - - Tetratricopeptide repeat
KHBLGEKB_00418 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHBLGEKB_00419 3.23e-90 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
KHBLGEKB_00420 3.64e-177 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_00421 3.37e-270 - - - E - - - Aminotransferase class I and II
KHBLGEKB_00422 2.21e-178 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHBLGEKB_00423 1.39e-135 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHBLGEKB_00424 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHBLGEKB_00425 0.0 - - - EGP - - - Major Facilitator Superfamily
KHBLGEKB_00426 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
KHBLGEKB_00427 0.0 - - - L - - - DEAD DEAH box helicase
KHBLGEKB_00428 1.68e-253 - - - S - - - Polyphosphate kinase 2 (PPK2)
KHBLGEKB_00429 6.57e-253 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHBLGEKB_00430 2.97e-144 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHBLGEKB_00431 1.45e-196 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KHBLGEKB_00432 9.73e-179 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
KHBLGEKB_00433 2.67e-109 - - - S - - - Aminoacyl-tRNA editing domain
KHBLGEKB_00434 4.51e-107 - - - K - - - helix_turn_helix, Lux Regulon
KHBLGEKB_00435 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KHBLGEKB_00436 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
KHBLGEKB_00437 5.86e-299 - - - S - - - Domain of Unknown Function (DUF349)
KHBLGEKB_00441 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
KHBLGEKB_00442 9.86e-237 uspA - - T - - - Belongs to the universal stress protein A family
KHBLGEKB_00443 1.49e-251 - - - S - - - Protein of unknown function (DUF3027)
KHBLGEKB_00444 7.13e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KHBLGEKB_00445 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHBLGEKB_00446 1.23e-171 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
KHBLGEKB_00447 6.66e-222 - - - - - - - -
KHBLGEKB_00448 8.25e-53 - - - S - - - Proteins of 100 residues with WXG
KHBLGEKB_00449 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHBLGEKB_00450 2.97e-41 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KHBLGEKB_00451 4.24e-105 - - - S - - - LytR cell envelope-related transcriptional attenuator
KHBLGEKB_00452 2.11e-185 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHBLGEKB_00453 1.22e-251 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
KHBLGEKB_00454 1.13e-225 - - - S - - - Protein of unknown function DUF58
KHBLGEKB_00455 3.59e-121 - - - - - - - -
KHBLGEKB_00456 1.86e-245 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
KHBLGEKB_00457 2.85e-198 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
KHBLGEKB_00458 2.27e-117 - - - - - - - -
KHBLGEKB_00460 0.0 - - - S - - - PGAP1-like protein
KHBLGEKB_00461 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
KHBLGEKB_00462 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
KHBLGEKB_00463 4.7e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
KHBLGEKB_00464 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KHBLGEKB_00465 1.05e-28 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
KHBLGEKB_00466 3.29e-202 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
KHBLGEKB_00467 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
KHBLGEKB_00468 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
KHBLGEKB_00469 2.25e-178 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
KHBLGEKB_00470 1.29e-233 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHBLGEKB_00471 3.86e-174 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KHBLGEKB_00472 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHBLGEKB_00473 7.86e-285 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHBLGEKB_00474 9.87e-70 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KHBLGEKB_00475 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
KHBLGEKB_00476 7.42e-212 - - - S - - - Protein conserved in bacteria
KHBLGEKB_00478 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KHBLGEKB_00479 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KHBLGEKB_00480 4.91e-144 - - - - - - - -
KHBLGEKB_00481 2.63e-313 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHBLGEKB_00482 1.87e-172 - - - S - - - Protein of unknown function (DUF3159)
KHBLGEKB_00483 3.78e-196 - - - S - - - Protein of unknown function (DUF3710)
KHBLGEKB_00484 5.8e-215 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
KHBLGEKB_00485 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KHBLGEKB_00486 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KHBLGEKB_00487 0.0 oppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHBLGEKB_00488 5.29e-212 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
KHBLGEKB_00489 4.8e-226 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHBLGEKB_00490 2.74e-235 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
KHBLGEKB_00491 2.67e-56 - - - - - - - -
KHBLGEKB_00492 2.1e-245 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
KHBLGEKB_00493 7.12e-254 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KHBLGEKB_00494 1.83e-109 - - - - - - - -
KHBLGEKB_00495 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
KHBLGEKB_00496 8.76e-299 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
KHBLGEKB_00497 9.56e-211 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
KHBLGEKB_00498 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
KHBLGEKB_00499 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KHBLGEKB_00500 6.03e-191 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
KHBLGEKB_00501 6.08e-145 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHBLGEKB_00502 8.34e-194 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHBLGEKB_00503 1.31e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
KHBLGEKB_00504 9.73e-228 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
KHBLGEKB_00505 5.46e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHBLGEKB_00506 3.31e-35 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
KHBLGEKB_00507 2.16e-137 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHBLGEKB_00508 1.4e-10 - - - S - - - Spermine/spermidine synthase domain
KHBLGEKB_00509 3.41e-172 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
KHBLGEKB_00510 3.39e-254 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHBLGEKB_00511 6.06e-119 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHBLGEKB_00513 5.38e-230 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KHBLGEKB_00514 7.58e-248 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KHBLGEKB_00515 3.35e-84 - - - - - - - -
KHBLGEKB_00516 9.94e-149 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KHBLGEKB_00517 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHBLGEKB_00518 1.26e-244 - - - V - - - Acetyltransferase (GNAT) domain
KHBLGEKB_00519 3.1e-289 - 2.6.1.33 - M ko:K20429 - ko00000,ko01000 DegT/DnrJ/EryC1/StrS aminotransferase family
KHBLGEKB_00520 6.99e-307 - 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp
KHBLGEKB_00521 2.31e-174 - 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KHBLGEKB_00522 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KHBLGEKB_00523 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
KHBLGEKB_00525 7.52e-126 - - - F - - - NUDIX domain
KHBLGEKB_00526 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
KHBLGEKB_00527 0.0 - - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHBLGEKB_00528 7.55e-249 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHBLGEKB_00529 3.06e-242 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHBLGEKB_00530 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KHBLGEKB_00531 4.41e-309 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
KHBLGEKB_00532 5.93e-196 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHBLGEKB_00533 2.39e-275 - - - GK - - - ROK family
KHBLGEKB_00534 1.98e-168 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
KHBLGEKB_00535 2.53e-284 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHBLGEKB_00536 2.87e-217 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
KHBLGEKB_00537 3.73e-301 - - - G - - - Major Facilitator Superfamily
KHBLGEKB_00538 2.9e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHBLGEKB_00541 1.01e-232 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
KHBLGEKB_00542 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KHBLGEKB_00543 3.15e-276 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHBLGEKB_00544 4.49e-297 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
KHBLGEKB_00545 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHBLGEKB_00546 8.76e-261 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHBLGEKB_00547 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KHBLGEKB_00548 2.48e-231 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHBLGEKB_00549 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
KHBLGEKB_00550 1.96e-97 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KHBLGEKB_00551 6.21e-246 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KHBLGEKB_00552 8.85e-118 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KHBLGEKB_00553 0.0 - - - L - - - DNA helicase
KHBLGEKB_00554 5.58e-291 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KHBLGEKB_00555 2.55e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHBLGEKB_00556 3.99e-64 - - - M - - - Lysin motif
KHBLGEKB_00557 3.03e-166 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHBLGEKB_00558 2.62e-211 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHBLGEKB_00559 1.88e-224 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KHBLGEKB_00560 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHBLGEKB_00561 3.25e-222 - - - - - - - -
KHBLGEKB_00562 2.51e-157 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
KHBLGEKB_00563 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
KHBLGEKB_00564 1.2e-241 - - - M - - - Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
KHBLGEKB_00565 5.77e-35 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator Superfamily
KHBLGEKB_00566 0.0 - - - S - - - Domain of unknown function (DUF5067)
KHBLGEKB_00567 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KHBLGEKB_00568 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
KHBLGEKB_00569 4.81e-167 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
KHBLGEKB_00570 2.24e-155 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KHBLGEKB_00571 1.84e-151 - - - - - - - -
KHBLGEKB_00572 1.08e-145 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
KHBLGEKB_00573 1.85e-285 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHBLGEKB_00574 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHBLGEKB_00575 2.91e-214 - - - S - - - Protein conserved in bacteria
KHBLGEKB_00578 1.19e-97 - - - S - - - Domain of unknown function (DUF4186)
KHBLGEKB_00579 3.65e-222 dkgV - - C - - - Aldo/keto reductase family
KHBLGEKB_00580 5.5e-199 - - - S - - - Aldo/keto reductase family
KHBLGEKB_00581 1.24e-258 - - - K - - - WYL domain
KHBLGEKB_00583 5e-05 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHBLGEKB_00584 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
KHBLGEKB_00585 1.9e-62 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
KHBLGEKB_00586 1.63e-155 - - - S - - - zinc-ribbon domain
KHBLGEKB_00587 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
KHBLGEKB_00588 1.11e-53 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KHBLGEKB_00589 1.32e-23 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KHBLGEKB_00590 1.65e-245 - - - S - - - Domain of unknown function (DUF1963)
KHBLGEKB_00591 2.53e-198 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHBLGEKB_00592 1.5e-184 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KHBLGEKB_00593 0.0 - - - I - - - acetylesterase activity
KHBLGEKB_00594 1.6e-298 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KHBLGEKB_00595 1.45e-280 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KHBLGEKB_00596 2.84e-313 - - - NU - - - Tfp pilus assembly protein FimV
KHBLGEKB_00598 3.79e-16 - - - L - - - PFAM Integrase catalytic
KHBLGEKB_00599 9.38e-13 - - - - - - - -
KHBLGEKB_00600 1.07e-115 - - - - - - - -
KHBLGEKB_00602 1.29e-186 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
KHBLGEKB_00603 1.38e-103 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KHBLGEKB_00604 5e-285 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
KHBLGEKB_00605 4.29e-203 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
KHBLGEKB_00606 8.34e-299 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
KHBLGEKB_00607 5.51e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHBLGEKB_00608 3.72e-220 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
KHBLGEKB_00609 1.25e-82 - - - - - - - -
KHBLGEKB_00611 1.89e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KHBLGEKB_00612 4.6e-148 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHBLGEKB_00613 1.65e-191 - - - V - - - DivIVA protein
KHBLGEKB_00614 1.35e-56 - - - S ko:K02221 - ko00000,ko02044 YGGT family
KHBLGEKB_00615 9.4e-105 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KHBLGEKB_00616 3.27e-294 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHBLGEKB_00617 8.15e-315 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHBLGEKB_00618 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
KHBLGEKB_00619 6.61e-134 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
KHBLGEKB_00620 4.15e-183 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KHBLGEKB_00621 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KHBLGEKB_00622 1.62e-110 - - - - - - - -
KHBLGEKB_00623 1.98e-290 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
KHBLGEKB_00624 1.21e-209 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KHBLGEKB_00625 2.08e-79 - - - S - - - Thiamine-binding protein
KHBLGEKB_00626 5.62e-179 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHBLGEKB_00627 4.52e-86 - - - S - - - Protein of unknown function (DUF3052)
KHBLGEKB_00628 2.91e-193 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KHBLGEKB_00629 0.0 - - - S - - - Zincin-like metallopeptidase
KHBLGEKB_00630 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KHBLGEKB_00631 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
KHBLGEKB_00632 9.31e-44 - - - S - - - Protein of unknown function (DUF3107)
KHBLGEKB_00633 2.09e-212 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
KHBLGEKB_00634 4.82e-147 - - - S - - - Vitamin K epoxide reductase
KHBLGEKB_00635 4.94e-214 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
KHBLGEKB_00636 5.49e-196 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KHBLGEKB_00637 1.31e-219 - - - S - - - Patatin-like phospholipase
KHBLGEKB_00638 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
KHBLGEKB_00639 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KHBLGEKB_00640 6.07e-116 - - - K - - - MarR family
KHBLGEKB_00642 0.0 - - - M - - - Parallel beta-helix repeats
KHBLGEKB_00643 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
KHBLGEKB_00644 4.55e-212 - - - - - - - -
KHBLGEKB_00645 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
KHBLGEKB_00647 5.91e-179 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHBLGEKB_00648 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
KHBLGEKB_00649 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHBLGEKB_00650 1.47e-56 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHBLGEKB_00651 2.23e-258 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
KHBLGEKB_00653 5.95e-05 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KHBLGEKB_00654 4.73e-234 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
KHBLGEKB_00655 0.0 - - - OP - - - Sulfurtransferase TusA
KHBLGEKB_00656 8.74e-193 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
KHBLGEKB_00657 4.8e-171 tmp1 - - S - - - Domain of unknown function (DUF4391)
KHBLGEKB_00658 1.3e-200 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
KHBLGEKB_00659 7.65e-293 aspB 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class-V
KHBLGEKB_00660 2.43e-129 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KHBLGEKB_00661 0.0 - - - S - - - zinc finger
KHBLGEKB_00662 3.18e-160 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHBLGEKB_00663 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHBLGEKB_00664 0.0 vpr - - O - - - Subtilase family
KHBLGEKB_00665 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
KHBLGEKB_00666 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHBLGEKB_00667 6.97e-208 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHBLGEKB_00668 1.16e-169 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KHBLGEKB_00669 1.19e-75 - - - L - - - Transposase
KHBLGEKB_00670 3.22e-33 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KHBLGEKB_00671 3.83e-13 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
KHBLGEKB_00672 8.46e-55 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
KHBLGEKB_00673 3.56e-86 gsiA - - P ko:K02031,ko:K02032,ko:K12371,ko:K13892 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHBLGEKB_00674 0.0 - - - G - - - Major Facilitator Superfamily
KHBLGEKB_00675 2.39e-195 - - - K - - - -acetyltransferase
KHBLGEKB_00676 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
KHBLGEKB_00677 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
KHBLGEKB_00678 0.0 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KHBLGEKB_00679 0.0 - - - S - - - Fibronectin type 3 domain
KHBLGEKB_00680 0.0 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
KHBLGEKB_00681 6.42e-299 - - - S - - - Protein of unknown function DUF58
KHBLGEKB_00682 0.0 - - - E - - - Transglutaminase-like superfamily
KHBLGEKB_00683 9.56e-211 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
KHBLGEKB_00684 1.2e-100 - - - B - - - Belongs to the OprB family
KHBLGEKB_00685 5.36e-124 - - - T - - - Forkhead associated domain
KHBLGEKB_00686 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHBLGEKB_00687 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHBLGEKB_00688 4.96e-126 - - - - - - - -
KHBLGEKB_00689 2.13e-234 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
KHBLGEKB_00690 3.46e-43 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Putative cell wall binding repeat
KHBLGEKB_00691 6.75e-76 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Putative cell wall binding repeat
KHBLGEKB_00692 5.27e-156 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KHBLGEKB_00693 8.76e-234 - - - S - - - Membrane
KHBLGEKB_00694 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
KHBLGEKB_00695 3.23e-58 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
KHBLGEKB_00696 1.32e-308 - - - EGP - - - Sugar (and other) transporter
KHBLGEKB_00697 2.4e-296 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
KHBLGEKB_00698 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
KHBLGEKB_00699 7e-186 - - - K - - - DeoR C terminal sensor domain
KHBLGEKB_00700 2.85e-289 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
KHBLGEKB_00701 3.02e-277 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
KHBLGEKB_00702 0.0 pon1 - - M - - - Transglycosylase
KHBLGEKB_00703 4.67e-173 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
KHBLGEKB_00704 8.97e-151 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
KHBLGEKB_00705 3.62e-245 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KHBLGEKB_00706 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
KHBLGEKB_00707 0.0 - - - S - - - Uncharacterized conserved protein (DUF2183)
KHBLGEKB_00708 2.17e-93 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
KHBLGEKB_00709 0.0 - - - S - - - L,D-transpeptidase catalytic domain
KHBLGEKB_00711 1.2e-204 - - - I - - - Alpha/beta hydrolase family
KHBLGEKB_00712 3.88e-152 - - - F - - - Domain of unknown function (DUF4916)
KHBLGEKB_00713 2.57e-78 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
KHBLGEKB_00714 2.49e-230 - - - S ko:K21688 - ko00000 G5
KHBLGEKB_00715 0.0 - - - - - - - -
KHBLGEKB_00716 9.03e-56 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
KHBLGEKB_00717 8.83e-147 - - - L ko:K07483 - ko00000 Integrase core domain
KHBLGEKB_00718 1.53e-123 rfbP - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KHBLGEKB_00719 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
KHBLGEKB_00720 2.93e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KHBLGEKB_00721 2.77e-158 - - - L - - - Protein of unknown function (DUF1524)
KHBLGEKB_00722 5.17e-218 - - - S - - - Oxidoreductase, aldo keto reductase family protein
KHBLGEKB_00723 1.61e-258 - - - K - - - helix_turn _helix lactose operon repressor
KHBLGEKB_00724 1.79e-142 - - - G - - - Glycosyl hydrolases family 43
KHBLGEKB_00725 7.08e-148 - - - G - - - Glycosyl hydrolases family 43
KHBLGEKB_00728 4.7e-143 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KHBLGEKB_00729 2.37e-198 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KHBLGEKB_00730 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
KHBLGEKB_00732 5.12e-266 - - - K - - - helix_turn _helix lactose operon repressor
KHBLGEKB_00733 1.9e-169 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHBLGEKB_00734 1.03e-201 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KHBLGEKB_00735 2.33e-81 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KHBLGEKB_00736 4.86e-166 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Class II Aldolase and Adducin N-terminal domain
KHBLGEKB_00737 6.29e-220 - 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
KHBLGEKB_00738 0.0 - 2.7.1.53 - G ko:K00880 ko00040,ko00053,map00040,map00053 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
KHBLGEKB_00739 1.46e-283 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KHBLGEKB_00740 8.57e-222 - - - K - - - Putative sugar-binding domain
KHBLGEKB_00741 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHBLGEKB_00742 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_00743 8.95e-74 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
KHBLGEKB_00744 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
KHBLGEKB_00745 4.87e-155 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
KHBLGEKB_00747 6.19e-263 - - - - - - - -
KHBLGEKB_00749 2.09e-272 - - - - - - - -
KHBLGEKB_00750 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KHBLGEKB_00753 6.28e-225 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
KHBLGEKB_00754 3.97e-152 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHBLGEKB_00755 6.69e-173 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KHBLGEKB_00756 1.17e-314 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHBLGEKB_00758 1.26e-118 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
KHBLGEKB_00759 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
KHBLGEKB_00760 1.56e-179 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KHBLGEKB_00761 2.72e-34 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KHBLGEKB_00762 8.83e-147 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
KHBLGEKB_00763 3.01e-184 - - - - - - - -
KHBLGEKB_00764 4.42e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHBLGEKB_00765 1.04e-76 - - - S - - - Protein of unknown function (DUF3039)
KHBLGEKB_00766 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
KHBLGEKB_00767 6.63e-174 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
KHBLGEKB_00768 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KHBLGEKB_00769 4.14e-212 - - - P - - - Cation efflux family
KHBLGEKB_00770 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHBLGEKB_00771 1.64e-283 - - - S - - - Endonuclease/Exonuclease/phosphatase family
KHBLGEKB_00772 5.28e-129 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
KHBLGEKB_00773 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
KHBLGEKB_00774 2.4e-80 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KHBLGEKB_00775 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KHBLGEKB_00776 1.08e-137 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHBLGEKB_00777 9.36e-229 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KHBLGEKB_00778 5.32e-108 - - - O - - - Hsp20/alpha crystallin family
KHBLGEKB_00779 1.93e-139 - - - S ko:K07078 - ko00000 Nitroreductase family
KHBLGEKB_00781 3.78e-156 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
KHBLGEKB_00782 0.0 - - - U ko:K06956 - ko00000 Sodium:dicarboxylate symporter family
KHBLGEKB_00783 0.0 - - - - - - - -
KHBLGEKB_00786 1.74e-278 steT - - E ko:K03294 - ko00000 amino acid
KHBLGEKB_00787 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
KHBLGEKB_00788 7.42e-41 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
KHBLGEKB_00789 2.69e-256 - - - G - - - pfkB family carbohydrate kinase
KHBLGEKB_00791 7.08e-308 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
KHBLGEKB_00792 9.29e-168 - - - K - - - helix_turn_helix, mercury resistance
KHBLGEKB_00794 1.77e-72 - - - L - - - RelB antitoxin
KHBLGEKB_00795 4.54e-46 - - - I - - - carboxylic ester hydrolase activity
KHBLGEKB_00796 1.01e-292 - - - K - - - Helix-turn-helix XRE-family like proteins
KHBLGEKB_00797 2.11e-160 tam 2.1.1.144 - S ko:K00598 - ko00000,ko01000 Methyltransferase domain
KHBLGEKB_00802 2.83e-39 - - - - - - - -
KHBLGEKB_00804 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
KHBLGEKB_00805 4.78e-54 - - - K - - - Transcriptional regulator
KHBLGEKB_00806 1.18e-85 - - - S ko:K06889 - ko00000 alpha beta
KHBLGEKB_00808 9.14e-13 - - - M - - - Belongs to the glycosyl hydrolase 28 family
KHBLGEKB_00809 3.94e-294 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
KHBLGEKB_00810 1.37e-306 - - - S - - - Psort location Cytoplasmic, score 8.87
KHBLGEKB_00811 1.51e-153 - - - K - - - Bacterial regulatory proteins, tetR family
KHBLGEKB_00812 2.44e-168 - - - M - - - Mechanosensitive ion channel
KHBLGEKB_00813 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KHBLGEKB_00815 5.72e-199 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
KHBLGEKB_00816 2.03e-147 - - - S - - - Domain of unknown function (DUF4854)
KHBLGEKB_00817 6.52e-271 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KHBLGEKB_00818 0.0 - - - M - - - LPXTG cell wall anchor motif
KHBLGEKB_00819 0.0 - - - M - - - domain protein
KHBLGEKB_00820 2.45e-70 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
KHBLGEKB_00821 3.39e-188 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHBLGEKB_00822 1.72e-247 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KHBLGEKB_00823 1.28e-174 - - - M - - - Protein of unknown function (DUF3152)
KHBLGEKB_00824 3.99e-176 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KHBLGEKB_00826 3.29e-53 - - - E - - - Domain of unknown function (DUF5011)
KHBLGEKB_00827 4.91e-28 istB - - L - - - IstB-like ATP binding protein
KHBLGEKB_00828 0.0 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
KHBLGEKB_00829 1.01e-65 - - - - - - - -
KHBLGEKB_00830 3e-77 - - - - - - - -
KHBLGEKB_00831 1.16e-120 - - - J - - - tRNA 5'-leader removal
KHBLGEKB_00833 1.71e-155 - - - S - - - CYTH
KHBLGEKB_00834 2.52e-214 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
KHBLGEKB_00835 4.83e-231 - - - - - - - -
KHBLGEKB_00836 2.08e-242 - - - - - - - -
KHBLGEKB_00837 5.14e-222 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
KHBLGEKB_00838 1.23e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KHBLGEKB_00839 1.43e-95 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHBLGEKB_00840 2.03e-185 - - - - - - - -
KHBLGEKB_00841 9.78e-169 - - - K - - - Bacterial regulatory proteins, tetR family
KHBLGEKB_00842 1.05e-292 - - - G - - - Transmembrane secretion effector
KHBLGEKB_00843 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHBLGEKB_00844 5.26e-281 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
KHBLGEKB_00845 1.74e-251 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KHBLGEKB_00847 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
KHBLGEKB_00848 3.31e-171 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KHBLGEKB_00849 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KHBLGEKB_00850 9.2e-179 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
KHBLGEKB_00851 0.0 - - - S - - - Calcineurin-like phosphoesterase
KHBLGEKB_00854 3.11e-84 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KHBLGEKB_00855 2.92e-124 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KHBLGEKB_00856 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHBLGEKB_00858 2.24e-157 - - - S - - - HAD hydrolase, family IA, variant 3
KHBLGEKB_00859 5.05e-258 - - - P - - - NMT1/THI5 like
KHBLGEKB_00860 2.03e-178 - - - P - - - Binding-protein-dependent transport system inner membrane component
KHBLGEKB_00861 9.77e-192 - - - - - - - -
KHBLGEKB_00862 1.3e-160 - - - G - - - Phosphoglycerate mutase family
KHBLGEKB_00863 0.0 - - - EGP - - - Major Facilitator Superfamily
KHBLGEKB_00864 6.15e-127 - - - S - - - GtrA-like protein
KHBLGEKB_00865 9.48e-83 - - - S - - - Macrophage migration inhibitory factor (MIF)
KHBLGEKB_00866 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
KHBLGEKB_00867 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
KHBLGEKB_00868 3.03e-139 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
KHBLGEKB_00869 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
KHBLGEKB_00871 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
KHBLGEKB_00872 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KHBLGEKB_00873 7.47e-123 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KHBLGEKB_00874 3.12e-244 - - - C - - - Aldo/keto reductase family
KHBLGEKB_00875 2.21e-41 - - - M - - - F5/8 type C domain
KHBLGEKB_00876 3.89e-68 - - - - - - - -
KHBLGEKB_00878 4.3e-144 - - - Q - - - 4'-phosphopantetheinyl transferase superfamily
KHBLGEKB_00879 1.11e-148 - - - K - - - WHG domain
KHBLGEKB_00880 1.56e-37 - - - IQ - - - [acyl-carrier-protein] S-malonyltransferase activity
KHBLGEKB_00881 0.0 - - - EGP - - - Major Facilitator Superfamily
KHBLGEKB_00882 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
KHBLGEKB_00883 1.29e-191 - - - L ko:K07454 - ko00000 HNH endonuclease
KHBLGEKB_00884 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KHBLGEKB_00885 0.0 - - - S - - - Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KHBLGEKB_00887 8.41e-106 - - - L ko:K07485 - ko00000 Transposase
KHBLGEKB_00888 7.13e-56 - - - O - - - Glutaredoxin
KHBLGEKB_00889 5.34e-190 - - - S ko:K07058 - ko00000 Virulence factor BrkB
KHBLGEKB_00890 1.38e-127 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
KHBLGEKB_00891 2.48e-48 urtE - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHBLGEKB_00892 5.48e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHBLGEKB_00893 2.21e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHBLGEKB_00894 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHBLGEKB_00895 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KHBLGEKB_00896 7.06e-132 - - - K - - - Transcriptional regulator C-terminal region
KHBLGEKB_00897 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
KHBLGEKB_00898 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KHBLGEKB_00900 3.84e-233 - - - S - - - Protein of unknown function (DUF559)
KHBLGEKB_00901 1.76e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KHBLGEKB_00902 6.15e-261 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KHBLGEKB_00903 0.0 - - - EGP - - - Sugar (and other) transporter
KHBLGEKB_00904 0.0 scrT - - G - - - Transporter major facilitator family protein
KHBLGEKB_00905 5.41e-100 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
KHBLGEKB_00906 1.81e-252 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHBLGEKB_00907 3.43e-79 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHBLGEKB_00908 1.02e-209 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHBLGEKB_00909 1.94e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHBLGEKB_00910 1.25e-252 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
KHBLGEKB_00911 0.0 - 3.2.1.8, 3.5.1.104 - G ko:K01181,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
KHBLGEKB_00913 3.57e-302 - - - U - - - Relaxase/Mobilisation nuclease domain
KHBLGEKB_00914 4.53e-45 - - - S - - - Bacterial mobilisation protein (MobC)
KHBLGEKB_00915 7.68e-104 - - - S - - - GyrI-like small molecule binding domain
KHBLGEKB_00916 1.03e-53 - - - S - - - Polyketide cyclase / dehydrase and lipid transport
KHBLGEKB_00917 6.31e-90 - - - K - - - FR47-like protein
KHBLGEKB_00918 9.59e-104 - - - S - - - Nucleotidyltransferase domain
KHBLGEKB_00919 2.08e-247 - - - - - - - -
KHBLGEKB_00920 7.01e-98 - - - S - - - Protein of unknown function DUF262
KHBLGEKB_00921 1.63e-63 - - - S - - - Protein of unknown function DUF262
KHBLGEKB_00923 2.44e-216 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KHBLGEKB_00924 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
KHBLGEKB_00925 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
KHBLGEKB_00926 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
KHBLGEKB_00927 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KHBLGEKB_00929 4.51e-110 - - - Q - - - Acetyltransferase (GNAT) domain
KHBLGEKB_00930 6.18e-199 - - - I - - - Serine aminopeptidase, S33
KHBLGEKB_00931 3.02e-70 - - - S - - - Putative heavy-metal-binding
KHBLGEKB_00932 3.91e-61 - - - D - - - DivIVA domain protein
KHBLGEKB_00933 3.85e-115 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
KHBLGEKB_00934 0.0 - - - KL - - - Domain of unknown function (DUF3427)
KHBLGEKB_00936 4.1e-251 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHBLGEKB_00938 1.92e-146 - - - - - - - -
KHBLGEKB_00939 1.94e-216 - - - EG - - - EamA-like transporter family
KHBLGEKB_00940 7.23e-265 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
KHBLGEKB_00941 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
KHBLGEKB_00942 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
KHBLGEKB_00943 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
KHBLGEKB_00944 3.69e-167 fhaA - - T - - - Protein of unknown function (DUF2662)
KHBLGEKB_00945 2.04e-122 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
KHBLGEKB_00946 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
KHBLGEKB_00947 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KHBLGEKB_00948 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
KHBLGEKB_00949 5.69e-234 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KHBLGEKB_00950 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KHBLGEKB_00951 9.5e-156 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
KHBLGEKB_00952 1.14e-295 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KHBLGEKB_00953 1.18e-182 - - - S - - - Bacterial protein of unknown function (DUF881)
KHBLGEKB_00954 8.05e-100 crgA - - D - - - Involved in cell division
KHBLGEKB_00955 0.0 - - - L - - - ribosomal rna small subunit methyltransferase
KHBLGEKB_00956 8.87e-118 - - - L - - - HTH-like domain
KHBLGEKB_00957 2.4e-186 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
KHBLGEKB_00958 7.68e-47 - - - - - - - -
KHBLGEKB_00959 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KHBLGEKB_00960 5.53e-96 - - - I - - - Sterol carrier protein
KHBLGEKB_00961 1.55e-42 - - - V ko:K06147 - ko00000,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_00962 1.48e-58 - - - L ko:K07485 - ko00000 Transposase
KHBLGEKB_00963 2.24e-58 istB - - L - - - IstB-like ATP binding protein
KHBLGEKB_00964 7.04e-57 - - - L - - - Integrase core domain
KHBLGEKB_00965 9.1e-108 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
KHBLGEKB_00966 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KHBLGEKB_00968 3.69e-278 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
KHBLGEKB_00969 0.0 - - - S - - - Domain of unknown function (DUF4037)
KHBLGEKB_00970 2.25e-144 - - - S - - - Protein of unknown function (DUF4125)
KHBLGEKB_00971 2.71e-195 - - - - - - - -
KHBLGEKB_00972 0.0 pspC - - KT - - - PspC domain
KHBLGEKB_00973 0.0 tcsS3 - - KT - - - PspC domain
KHBLGEKB_00974 5.87e-163 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
KHBLGEKB_00975 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHBLGEKB_00976 5.83e-181 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
KHBLGEKB_00977 4.36e-239 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
KHBLGEKB_00978 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHBLGEKB_00979 2.95e-121 - - - - - - - -
KHBLGEKB_00981 0.0 - 3.2.1.50 - G ko:K01205 ko00531,ko01100,ko04142,map00531,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko04147 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
KHBLGEKB_00983 1.21e-302 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHBLGEKB_00984 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
KHBLGEKB_00985 1.12e-270 - - - I - - - Diacylglycerol kinase catalytic domain
KHBLGEKB_00986 1.45e-197 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KHBLGEKB_00987 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
KHBLGEKB_00989 1.74e-95 - - - M - - - Spy0128-like isopeptide containing domain
KHBLGEKB_00991 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
KHBLGEKB_00992 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHBLGEKB_00993 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
KHBLGEKB_00994 2.41e-258 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHBLGEKB_00995 7.42e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHBLGEKB_00996 5.18e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
KHBLGEKB_00997 1.63e-140 - - - - - - - -
KHBLGEKB_00998 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHBLGEKB_00999 6.67e-300 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
KHBLGEKB_01000 2.35e-290 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHBLGEKB_01001 1.77e-123 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHBLGEKB_01002 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHBLGEKB_01003 8.14e-242 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KHBLGEKB_01004 4.96e-222 - - - - - - - -
KHBLGEKB_01005 3.08e-110 tnp3503b - - L - - - Transposase and inactivated derivatives
KHBLGEKB_01007 5.51e-199 - - - E - - - Transglutaminase/protease-like homologues
KHBLGEKB_01008 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
KHBLGEKB_01009 2.01e-219 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KHBLGEKB_01010 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
KHBLGEKB_01011 3.77e-95 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KHBLGEKB_01012 1.4e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHBLGEKB_01013 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHBLGEKB_01014 2.84e-82 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHBLGEKB_01015 1.03e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KHBLGEKB_01016 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHBLGEKB_01017 4.79e-129 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KHBLGEKB_01018 0.0 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KHBLGEKB_01019 1.51e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KHBLGEKB_01020 1.46e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
KHBLGEKB_01021 5.38e-147 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHBLGEKB_01022 1.53e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHBLGEKB_01023 2.69e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHBLGEKB_01024 9.65e-91 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHBLGEKB_01025 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHBLGEKB_01026 1.6e-133 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHBLGEKB_01027 9.32e-70 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHBLGEKB_01028 7.32e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHBLGEKB_01029 9.4e-57 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHBLGEKB_01030 6.77e-51 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KHBLGEKB_01031 2.71e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHBLGEKB_01032 5.27e-159 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHBLGEKB_01033 2.21e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHBLGEKB_01034 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHBLGEKB_01035 1.15e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHBLGEKB_01036 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KHBLGEKB_01037 1.34e-154 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KHBLGEKB_01038 6.65e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHBLGEKB_01039 5.42e-67 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KHBLGEKB_01040 8.68e-24 - - - S - - - YwiC-like protein
KHBLGEKB_01041 1.36e-213 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KHBLGEKB_01042 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KHBLGEKB_01043 2.39e-295 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
KHBLGEKB_01044 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
KHBLGEKB_01045 1.71e-99 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KHBLGEKB_01046 2.64e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHBLGEKB_01047 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
KHBLGEKB_01048 7.22e-153 - - - - - - - -
KHBLGEKB_01049 1.63e-146 yigZ - - S - - - Uncharacterized protein family UPF0029
KHBLGEKB_01050 0.0 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
KHBLGEKB_01052 1.74e-302 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHBLGEKB_01053 5.74e-285 dapC - - E - - - Aminotransferase class I and II
KHBLGEKB_01054 3.55e-81 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
KHBLGEKB_01055 4.5e-279 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
KHBLGEKB_01056 2.71e-35 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
KHBLGEKB_01060 3.93e-74 - - - KLT - - - Associated with various cellular activities
KHBLGEKB_01061 2.01e-165 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
KHBLGEKB_01062 3.49e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHBLGEKB_01063 7.19e-256 - - - - - - - -
KHBLGEKB_01064 9.98e-121 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KHBLGEKB_01065 5.69e-154 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
KHBLGEKB_01066 1.88e-51 - - - S - - - Putative regulatory protein
KHBLGEKB_01067 2.1e-141 - - - NO - - - SAF
KHBLGEKB_01068 1.66e-55 - - - - - - - -
KHBLGEKB_01069 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
KHBLGEKB_01070 0.0 - - - T - - - Forkhead associated domain
KHBLGEKB_01072 5.13e-61 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KHBLGEKB_01073 5.06e-115 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHBLGEKB_01074 5.87e-229 xynB2 1.1.1.169 - E ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 lipolytic protein G-D-S-L family
KHBLGEKB_01075 0.0 - - - G - - - BNR repeat-like domain
KHBLGEKB_01077 5.92e-313 - - - S ko:K06901 - ko00000,ko02000 Permease family
KHBLGEKB_01079 1.74e-217 - - - S - - - Protein conserved in bacteria
KHBLGEKB_01080 1.29e-189 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHBLGEKB_01081 7.7e-233 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
KHBLGEKB_01082 8.51e-219 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KHBLGEKB_01083 1.71e-262 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
KHBLGEKB_01084 5.44e-165 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
KHBLGEKB_01085 8.66e-310 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
KHBLGEKB_01086 2.57e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHBLGEKB_01087 0.0 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KHBLGEKB_01088 0.0 - - - K - - - Putative DNA-binding domain
KHBLGEKB_01089 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KHBLGEKB_01090 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KHBLGEKB_01091 9.62e-142 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KHBLGEKB_01092 3.54e-185 - - - S - - - Putative ABC-transporter type IV
KHBLGEKB_01093 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHBLGEKB_01094 9.19e-293 - - - L - - - Tetratricopeptide repeat
KHBLGEKB_01095 1.53e-242 - - - G - - - Haloacid dehalogenase-like hydrolase
KHBLGEKB_01097 9.34e-175 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KHBLGEKB_01098 1.03e-139 - - - - - - - -
KHBLGEKB_01099 5.24e-150 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
KHBLGEKB_01100 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
KHBLGEKB_01101 3.15e-235 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHBLGEKB_01102 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KHBLGEKB_01103 1.24e-158 - - - S - - - Haloacid dehalogenase-like hydrolase
KHBLGEKB_01104 2.84e-77 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
KHBLGEKB_01105 2.47e-224 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_01106 6.5e-163 - - - S - - - ABC-2 family transporter protein
KHBLGEKB_01107 3.24e-158 - - - S - - - ABC-2 family transporter protein
KHBLGEKB_01108 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
KHBLGEKB_01109 2.93e-299 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KHBLGEKB_01110 4.42e-121 - - - - - - - -
KHBLGEKB_01111 5.93e-187 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHBLGEKB_01112 2.54e-243 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHBLGEKB_01114 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHBLGEKB_01115 6.1e-89 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KHBLGEKB_01116 1.92e-176 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
KHBLGEKB_01117 2.55e-100 - - - S - - - Bacterial PH domain
KHBLGEKB_01118 0.0 treS_1 - - G - - - Alpha amylase, catalytic domain
KHBLGEKB_01120 1.58e-158 - - - - - - - -
KHBLGEKB_01121 2.32e-169 - - - C - - - Putative TM nitroreductase
KHBLGEKB_01122 6.22e-188 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
KHBLGEKB_01123 3.34e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
KHBLGEKB_01124 1.06e-67 - - - KT - - - RESPONSE REGULATOR receiver
KHBLGEKB_01125 5.57e-247 - - - V - - - VanZ like family
KHBLGEKB_01126 5.99e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KHBLGEKB_01127 2.67e-124 - - - S - - - Putative ABC-transporter type IV
KHBLGEKB_01128 5.09e-203 - - - - - - - -
KHBLGEKB_01130 3.33e-128 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
KHBLGEKB_01131 3.19e-38 - - - EGP ko:K03446,ko:K03466,ko:K03762,ko:K08217 - br01600,ko00000,ko00002,ko01504,ko02000,ko03036 Major facilitator Superfamily
KHBLGEKB_01132 9.32e-225 - - - M - - - heme binding
KHBLGEKB_01133 1.31e-103 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHBLGEKB_01135 1.72e-52 - - - - - - - -
KHBLGEKB_01136 1.4e-170 - - - S - - - SOS response associated peptidase (SRAP)
KHBLGEKB_01137 4.77e-97 qseC 2.7.13.3 - T ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351 ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 Histidine kinase
KHBLGEKB_01138 4.88e-236 - - - S - - - Acetyltransferase (GNAT) domain
KHBLGEKB_01140 3.14e-117 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
KHBLGEKB_01141 6.31e-42 - - - K - - - Transcriptional regulator
KHBLGEKB_01142 2.67e-117 - - - K - - - FR47-like protein
KHBLGEKB_01143 1.3e-161 - - - J - - - Acetyltransferase (GNAT) domain
KHBLGEKB_01144 9.61e-84 - - - K - - - Protein of unknown function, DUF488
KHBLGEKB_01145 9.92e-206 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KHBLGEKB_01146 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
KHBLGEKB_01147 9.92e-184 - - - S - - - Domain of unknown function (DUF4194)
KHBLGEKB_01148 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
KHBLGEKB_01149 0.0 - - - E - - - Serine carboxypeptidase
KHBLGEKB_01150 1.72e-208 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
KHBLGEKB_01151 2.45e-218 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KHBLGEKB_01152 7.56e-214 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KHBLGEKB_01153 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KHBLGEKB_01154 2.02e-161 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
KHBLGEKB_01155 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
KHBLGEKB_01156 2.59e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KHBLGEKB_01157 3.13e-153 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
KHBLGEKB_01158 2.83e-203 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
KHBLGEKB_01159 7.03e-134 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
KHBLGEKB_01160 1.61e-250 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHBLGEKB_01162 2.46e-167 - - - M - - - Peptidase family M23
KHBLGEKB_01163 0.0 fadD1 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
KHBLGEKB_01164 0.0 - - - G - - - ABC transporter substrate-binding protein
KHBLGEKB_01165 1.35e-306 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
KHBLGEKB_01166 1.59e-255 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
KHBLGEKB_01167 3.59e-118 - - - - - - - -
KHBLGEKB_01168 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
KHBLGEKB_01169 4.26e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHBLGEKB_01170 3.07e-188 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KHBLGEKB_01171 4.78e-188 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHBLGEKB_01172 3.84e-165 - - - S - - - alpha beta
KHBLGEKB_01173 6.31e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KHBLGEKB_01174 6.26e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KHBLGEKB_01175 1.27e-226 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
KHBLGEKB_01176 1.48e-289 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KHBLGEKB_01177 1.82e-179 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KHBLGEKB_01178 4.17e-97 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHBLGEKB_01179 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHBLGEKB_01180 6.09e-311 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHBLGEKB_01181 3.93e-223 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHBLGEKB_01182 5.52e-215 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
KHBLGEKB_01183 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
KHBLGEKB_01184 1.69e-228 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHBLGEKB_01185 3.68e-277 - - - GK - - - ROK family
KHBLGEKB_01186 1.41e-263 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
KHBLGEKB_01187 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KHBLGEKB_01188 8.31e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KHBLGEKB_01189 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
KHBLGEKB_01190 6.89e-180 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KHBLGEKB_01191 0.0 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KHBLGEKB_01192 8.67e-151 - - - K - - - Transcriptional regulatory protein, C terminal
KHBLGEKB_01193 3.65e-08 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KHBLGEKB_01194 2.59e-110 - - - - - - - -
KHBLGEKB_01195 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KHBLGEKB_01196 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHBLGEKB_01197 2.6e-231 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
KHBLGEKB_01198 3.02e-227 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KHBLGEKB_01199 3.23e-222 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KHBLGEKB_01200 6.71e-284 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
KHBLGEKB_01201 3.84e-189 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHBLGEKB_01202 1.2e-45 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
KHBLGEKB_01203 1.18e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KHBLGEKB_01204 2.44e-208 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHBLGEKB_01205 1.49e-308 - - - V - - - MatE
KHBLGEKB_01207 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KHBLGEKB_01208 3.12e-182 - - - S - - - Protein of unknown function (DUF1275)
KHBLGEKB_01209 4.49e-258 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHBLGEKB_01210 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
KHBLGEKB_01211 1.54e-274 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KHBLGEKB_01212 6.31e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KHBLGEKB_01213 8.17e-204 - - - G - - - Fructosamine kinase
KHBLGEKB_01214 8.18e-216 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KHBLGEKB_01215 2.89e-199 - - - S - - - PAC2 family
KHBLGEKB_01219 0.0 - - - - - - - -
KHBLGEKB_01222 0.0 - - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHBLGEKB_01223 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHBLGEKB_01224 0.0 - 3.2.1.52 GH20 M ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
KHBLGEKB_01225 2.79e-176 yebC - - K - - - transcriptional regulatory protein
KHBLGEKB_01226 2.64e-129 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KHBLGEKB_01228 3.69e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KHBLGEKB_01229 8.06e-258 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KHBLGEKB_01230 5.39e-65 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
KHBLGEKB_01231 3.9e-131 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHBLGEKB_01232 8.17e-285 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KHBLGEKB_01233 9.52e-212 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KHBLGEKB_01234 1.1e-313 - - - - - - - -
KHBLGEKB_01235 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KHBLGEKB_01236 5.17e-56 - - - - - - - -
KHBLGEKB_01237 2.83e-166 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KHBLGEKB_01238 9.44e-187 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KHBLGEKB_01239 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KHBLGEKB_01240 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KHBLGEKB_01241 1.07e-208 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KHBLGEKB_01242 2.07e-237 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHBLGEKB_01243 8.92e-144 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
KHBLGEKB_01244 1.2e-54 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
KHBLGEKB_01245 1.07e-200 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
KHBLGEKB_01246 2.22e-151 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHBLGEKB_01247 5.59e-223 - - - S - - - Bacterial protein of unknown function (DUF881)
KHBLGEKB_01248 2.78e-57 sbp - - S - - - Protein of unknown function (DUF1290)
KHBLGEKB_01249 2.65e-180 - - - S - - - Bacterial protein of unknown function (DUF881)
KHBLGEKB_01250 2.88e-96 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
KHBLGEKB_01251 5.64e-153 merR2 - - K - - - helix_turn_helix, mercury resistance
KHBLGEKB_01252 2.84e-82 - - - - - - - -
KHBLGEKB_01254 4.2e-31 - - - L - - - DNA integration
KHBLGEKB_01255 4.36e-162 - - - S - - - GyrI-like small molecule binding domain
KHBLGEKB_01256 3.01e-117 - - - K - - - Putative zinc ribbon domain
KHBLGEKB_01259 5.93e-183 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
KHBLGEKB_01260 1.11e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
KHBLGEKB_01261 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
KHBLGEKB_01262 1.29e-70 - - - - - - - -
KHBLGEKB_01263 0.0 - - - K - - - WYL domain
KHBLGEKB_01264 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KHBLGEKB_01266 5.71e-78 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
KHBLGEKB_01267 4.33e-185 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KHBLGEKB_01268 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHBLGEKB_01269 6.72e-158 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KHBLGEKB_01270 1.23e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
KHBLGEKB_01271 7.12e-75 - - - T - - - Domain of unknown function (DUF4234)
KHBLGEKB_01272 7.13e-35 - - - T - - - Domain of unknown function (DUF4234)
KHBLGEKB_01273 1.59e-129 - - - K - - - Bacterial regulatory proteins, tetR family
KHBLGEKB_01274 9.14e-25 - - - - - - - -
KHBLGEKB_01275 6.69e-61 tam 2.1.1.144, 2.1.1.197 - FG ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 trans-aconitate 2-methyltransferase activity
KHBLGEKB_01276 1.17e-54 - - - K - - - Helix-turn-helix
KHBLGEKB_01277 3.44e-285 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA N-terminal domain
KHBLGEKB_01278 2.58e-89 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
KHBLGEKB_01279 3.24e-226 - - - S ko:K07088 - ko00000 Membrane transport protein
KHBLGEKB_01280 2.51e-120 - - - K - - - Transcriptional regulator PadR-like family
KHBLGEKB_01281 2.69e-172 - - - L ko:K07457 - ko00000 endonuclease III
KHBLGEKB_01282 6.88e-169 - - - S - - - Enoyl-(Acyl carrier protein) reductase
KHBLGEKB_01283 8.03e-311 - - - V - - - MatE
KHBLGEKB_01284 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHBLGEKB_01285 1.76e-19 - - - KLT - - - Protein tyrosine kinase
KHBLGEKB_01286 6.71e-207 - - - - - - - -
KHBLGEKB_01287 1.09e-248 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
KHBLGEKB_01288 9.04e-34 - - - K - - - MerR family regulatory protein
KHBLGEKB_01289 5.01e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHBLGEKB_01290 1.01e-229 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHBLGEKB_01291 3.07e-201 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
KHBLGEKB_01292 3.99e-231 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
KHBLGEKB_01293 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHBLGEKB_01294 1.83e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
KHBLGEKB_01295 2.71e-234 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KHBLGEKB_01296 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
KHBLGEKB_01298 8.19e-209 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
KHBLGEKB_01299 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHBLGEKB_01300 1.67e-128 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
KHBLGEKB_01301 2e-265 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KHBLGEKB_01302 3.14e-225 - - - I - - - alpha/beta hydrolase fold
KHBLGEKB_01303 1.17e-34 - - - S - - - Rard protein
KHBLGEKB_01304 3.16e-118 - - - E - - - Rard protein
KHBLGEKB_01305 7.96e-41 - - - - - - - -
KHBLGEKB_01306 0.0 - - - S - - - Protein of unknown function DUF262
KHBLGEKB_01307 6.65e-317 - - - S ko:K06915 - ko00000 AAA-like domain
KHBLGEKB_01308 1.57e-67 - - - S - - - SIR2-like domain
KHBLGEKB_01309 6.12e-233 - - - V - - - Type III restriction enzyme res subunit
KHBLGEKB_01310 3.01e-71 - - - L - - - Eco57I restriction-modification methylase
KHBLGEKB_01311 3.18e-49 - - - L - - - Eco57I restriction-modification methylase
KHBLGEKB_01312 0.0 - - - KL - - - Type III restriction enzyme res subunit
KHBLGEKB_01313 1.09e-168 - - - - - - - -
KHBLGEKB_01314 2.81e-228 - - - L ko:K07485 - ko00000 Transposase
KHBLGEKB_01315 7.87e-51 - - - L - - - Helix-turn-helix domain
KHBLGEKB_01316 1.11e-239 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHBLGEKB_01317 4.78e-143 - - - S ko:K07126 - ko00000 Sel1-like repeats.
KHBLGEKB_01318 2.18e-203 - - - S ko:K11206 - ko00000,ko01000 Carbon-nitrogen hydrolase
KHBLGEKB_01319 4.56e-209 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_01320 5.58e-311 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
KHBLGEKB_01321 5.23e-107 - - - - - - - -
KHBLGEKB_01322 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KHBLGEKB_01323 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
KHBLGEKB_01324 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
KHBLGEKB_01325 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
KHBLGEKB_01326 9.79e-18 - - - S ko:K07149 - ko00000 Membrane
KHBLGEKB_01327 3.85e-311 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KHBLGEKB_01328 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHBLGEKB_01329 3.91e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KHBLGEKB_01330 2.68e-174 - - - S - - - UPF0126 domain
KHBLGEKB_01331 3.19e-58 - - - T - - - RNA ligase
KHBLGEKB_01333 1.11e-287 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
KHBLGEKB_01334 2.53e-240 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHBLGEKB_01335 1.06e-197 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_01336 1.38e-183 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
KHBLGEKB_01337 1.5e-209 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHBLGEKB_01338 1.72e-218 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHBLGEKB_01339 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KHBLGEKB_01340 2.65e-184 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KHBLGEKB_01341 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHBLGEKB_01342 3.42e-84 - - - G ko:K02027 - ko00000,ko00002,ko02000 carbohydrate transport
KHBLGEKB_01343 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KHBLGEKB_01344 4.22e-160 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
KHBLGEKB_01345 2.17e-243 - - - K - - - Periplasmic binding protein domain
KHBLGEKB_01346 3.53e-25 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KHBLGEKB_01347 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
KHBLGEKB_01349 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHBLGEKB_01350 4.8e-73 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
KHBLGEKB_01351 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
KHBLGEKB_01352 8.77e-179 hflK - - O - - - prohibitin homologues
KHBLGEKB_01353 1.81e-310 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
KHBLGEKB_01354 3.15e-298 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
KHBLGEKB_01355 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
KHBLGEKB_01356 9.17e-284 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KHBLGEKB_01357 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_01358 0.0 - - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KHBLGEKB_01359 2.11e-249 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
KHBLGEKB_01360 2.92e-131 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
KHBLGEKB_01361 0.0 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
KHBLGEKB_01362 6.17e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KHBLGEKB_01363 1.56e-186 - - - S - - - Short repeat of unknown function (DUF308)
KHBLGEKB_01364 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
KHBLGEKB_01365 1.9e-154 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
KHBLGEKB_01366 5.42e-219 - - - - - - - -
KHBLGEKB_01367 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KHBLGEKB_01368 2.45e-230 - - - I - - - PAP2 superfamily
KHBLGEKB_01369 2.83e-47 - - - NU - - - Tfp pilus assembly protein FimV
KHBLGEKB_01370 0.0 - - - L - - - PIF1-like helicase
KHBLGEKB_01371 6.98e-206 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHBLGEKB_01372 1.91e-156 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
KHBLGEKB_01373 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
KHBLGEKB_01374 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KHBLGEKB_01375 1.06e-260 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
KHBLGEKB_01376 7.44e-151 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
KHBLGEKB_01377 3.71e-78 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
KHBLGEKB_01378 5.94e-237 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KHBLGEKB_01379 1.66e-246 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHBLGEKB_01380 1.85e-48 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
KHBLGEKB_01382 5.15e-247 - - - K ko:K13633 - ko00000,ko03000 helix_turn_helix, arabinose operon control protein
KHBLGEKB_01383 1.58e-208 - - - G ko:K05340 - ko00000,ko02000 Sugar transport protein
KHBLGEKB_01384 1.92e-239 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
KHBLGEKB_01385 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
KHBLGEKB_01386 3.57e-144 - - - - - - - -
KHBLGEKB_01387 2.66e-217 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
KHBLGEKB_01388 7.95e-189 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
KHBLGEKB_01389 0.0 - - - JKL - - - helicase superfamily c-terminal domain
KHBLGEKB_01390 1.23e-210 - - - EG - - - EamA-like transporter family
KHBLGEKB_01391 4.81e-185 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHBLGEKB_01392 3.93e-189 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
KHBLGEKB_01394 7.33e-271 - - - S - - - Psort location Cytoplasmic, score 8.87
KHBLGEKB_01395 0.0 - 2.5.1.49 - H ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.98
KHBLGEKB_01396 4.43e-58 - - - C - - - Aldo/keto reductase family
KHBLGEKB_01397 1.94e-94 - - - EGP - - - Major facilitator superfamily
KHBLGEKB_01398 3.68e-229 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHBLGEKB_01399 0.0 - - - S - - - ATPases associated with a variety of cellular activities
KHBLGEKB_01400 2.9e-75 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
KHBLGEKB_01401 1.7e-200 - - - I - - - alpha/beta hydrolase fold
KHBLGEKB_01402 4.04e-149 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
KHBLGEKB_01404 7.29e-65 - - - S - - - DUF218 domain
KHBLGEKB_01405 8.79e-139 - - - S - - - Protein of unknown function (DUF969)
KHBLGEKB_01406 1.54e-201 - - - S - - - Protein of unknown function (DUF979)
KHBLGEKB_01407 2.05e-146 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHBLGEKB_01409 1.76e-161 - - - - - - - -
KHBLGEKB_01410 1.66e-224 - - - M - - - domain, Protein
KHBLGEKB_01411 8.64e-24 - - - M - - - domain, Protein
KHBLGEKB_01412 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
KHBLGEKB_01413 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
KHBLGEKB_01414 1.88e-219 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
KHBLGEKB_01415 2.35e-107 - - - S - - - Protein of unknown function (DUF3180)
KHBLGEKB_01416 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHBLGEKB_01417 1.12e-210 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KHBLGEKB_01418 2.05e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
KHBLGEKB_01419 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHBLGEKB_01420 2.65e-127 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KHBLGEKB_01421 3.48e-269 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KHBLGEKB_01422 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
KHBLGEKB_01423 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
KHBLGEKB_01424 2.26e-215 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_01425 3.97e-295 - - - M - - - Glycosyl transferase family 21
KHBLGEKB_01426 0.0 - - - S - - - AI-2E family transporter
KHBLGEKB_01427 1.89e-227 - - - M - - - Glycosyltransferase like family 2
KHBLGEKB_01428 1.48e-271 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
KHBLGEKB_01431 4.46e-100 - - - S - - - Domain of unknown function (DUF4190)
KHBLGEKB_01432 4.62e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KHBLGEKB_01433 2.24e-194 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KHBLGEKB_01435 6.43e-16 - - - - - - - -
KHBLGEKB_01436 3.18e-30 - - - - - - - -
KHBLGEKB_01437 3.68e-296 - - - S - - - Helix-turn-helix domain
KHBLGEKB_01438 4.34e-126 - - - S ko:K18955 - ko00000,ko03000 Transcription factor WhiB
KHBLGEKB_01439 2.08e-133 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
KHBLGEKB_01440 1.43e-47 - - - - - - - -
KHBLGEKB_01441 1.03e-91 - - - - - - - -
KHBLGEKB_01442 3.5e-36 - - - - - - - -
KHBLGEKB_01443 6.52e-157 - - - K - - - Helix-turn-helix domain protein
KHBLGEKB_01445 0.0 - - - M - - - Cell surface antigen C-terminus
KHBLGEKB_01446 2.3e-56 - - - V ko:K01992 - ko00000,ko00002,ko02000 PFAM ABC-2 type transporter
KHBLGEKB_01447 4.07e-50 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
KHBLGEKB_01450 2.76e-104 - - - - - - - -
KHBLGEKB_01451 3.3e-138 - - - - - - - -
KHBLGEKB_01452 8.73e-154 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHBLGEKB_01453 1.98e-125 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
KHBLGEKB_01454 4.57e-248 - - - - - - - -
KHBLGEKB_01455 6.87e-172 - - - V - - - ABC transporter
KHBLGEKB_01456 1.35e-239 - - - V - - - Putative peptidoglycan binding domain
KHBLGEKB_01457 2.29e-154 - - - - - - - -
KHBLGEKB_01458 1.03e-77 - - - - - - - -
KHBLGEKB_01459 1.02e-153 - - - K - - - Transcriptional regulatory protein, C terminal
KHBLGEKB_01460 1.1e-296 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 GHKL domain
KHBLGEKB_01461 1e-125 - - - K - - - transcriptional regulator
KHBLGEKB_01462 1.78e-57 - - - - - - - -
KHBLGEKB_01463 1.44e-42 - - - - - - - -
KHBLGEKB_01464 2.17e-183 - - - - - - - -
KHBLGEKB_01465 7.5e-83 - - - S - - - PrgI family protein
KHBLGEKB_01466 0.0 - - - U - - - type IV secretory pathway VirB4
KHBLGEKB_01467 3.71e-265 - - - M - - - CHAP domain
KHBLGEKB_01468 4.29e-91 - - - - - - - -
KHBLGEKB_01469 2.16e-117 - - - - - - - -
KHBLGEKB_01470 1.12e-74 - - - - - - - -
KHBLGEKB_01473 1.1e-155 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHBLGEKB_01476 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
KHBLGEKB_01477 7.01e-83 - - - - - - - -
KHBLGEKB_01478 5.65e-60 - - - - - - - -
KHBLGEKB_01479 6.3e-161 - - - - - - - -
KHBLGEKB_01480 1.33e-312 - - - S - - - Antirestriction protein (ArdA)
KHBLGEKB_01481 5.98e-169 - - - - - - - -
KHBLGEKB_01482 2.79e-184 - - - S - - - Protein of unknown function (DUF3801)
KHBLGEKB_01483 1.89e-311 - - - U - - - Relaxase/Mobilisation nuclease domain
KHBLGEKB_01484 1.08e-88 - - - S - - - Bacterial mobilisation protein (MobC)
KHBLGEKB_01485 1.96e-96 - - - - - - - -
KHBLGEKB_01486 6.28e-54 - - - - - - - -
KHBLGEKB_01487 4.13e-308 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 ParB-like nuclease domain
KHBLGEKB_01488 3.49e-126 - - - S - - - Domain of unknown function (DUF4192)
KHBLGEKB_01489 2.09e-205 - - - T - - - Histidine kinase
KHBLGEKB_01490 8.98e-139 - - - K - - - helix_turn_helix, Lux Regulon
KHBLGEKB_01491 4.92e-89 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KHBLGEKB_01492 2.01e-20 - - - - - - - -
KHBLGEKB_01493 8.1e-220 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KHBLGEKB_01494 5.42e-41 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KHBLGEKB_01495 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
KHBLGEKB_01496 1.22e-100 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KHBLGEKB_01497 2.4e-91 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHBLGEKB_01498 1.12e-60 - - - T - - - Histidine kinase
KHBLGEKB_01499 1.16e-95 - - - K - - - Bacterial regulatory proteins, luxR family
KHBLGEKB_01500 1.38e-96 - - - KLT - - - serine threonine protein kinase
KHBLGEKB_01502 2.68e-35 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Protease II
KHBLGEKB_01503 3.37e-90 - - - G - - - Glycosyl hydrolase family 20, domain 2
KHBLGEKB_01504 8.68e-293 intA - - L - - - Phage integrase family
KHBLGEKB_01505 1.27e-10 intA - - L - - - Phage integrase family
KHBLGEKB_01508 1.66e-283 intA - - L - - - Phage integrase family
KHBLGEKB_01509 1.31e-108 - - - - - - - -
KHBLGEKB_01510 9.25e-27 - - - S - - - Helix-turn-helix domain
KHBLGEKB_01511 7.77e-24 - - - S ko:K18955 - ko00000,ko03000 Transcription factor WhiB
KHBLGEKB_01512 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
KHBLGEKB_01513 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KHBLGEKB_01514 5.98e-111 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
KHBLGEKB_01515 9.07e-228 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
KHBLGEKB_01516 1.35e-299 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KHBLGEKB_01517 5.05e-153 - - - K - - - Transcriptional regulatory protein, C terminal
KHBLGEKB_01519 3.34e-131 - - - - - - - -
KHBLGEKB_01520 6.51e-234 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
KHBLGEKB_01521 1.11e-138 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KHBLGEKB_01522 4.81e-236 - - - - - - - -
KHBLGEKB_01523 2.57e-14 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
KHBLGEKB_01524 1.25e-288 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KHBLGEKB_01525 7.89e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
KHBLGEKB_01526 3.41e-143 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHBLGEKB_01527 1.55e-66 - - - E - - - Branched-chain amino acid transport protein (AzlD)
KHBLGEKB_01528 1.04e-248 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
KHBLGEKB_01529 2e-125 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
KHBLGEKB_01530 5.46e-165 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
KHBLGEKB_01531 4.99e-223 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHBLGEKB_01532 1.52e-94 - - - O - - - OsmC-like protein
KHBLGEKB_01533 1.31e-244 - - - T - - - Universal stress protein family
KHBLGEKB_01534 9.72e-153 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
KHBLGEKB_01535 1.05e-231 - - - S - - - CHAP domain
KHBLGEKB_01536 2e-274 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHBLGEKB_01537 4.6e-53 - - - - - - - -
KHBLGEKB_01538 3.76e-287 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHBLGEKB_01539 9.33e-153 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KHBLGEKB_01540 2.85e-13 - - - EGP - - - Major Facilitator Superfamily
KHBLGEKB_01541 3.69e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHBLGEKB_01542 2.37e-223 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
KHBLGEKB_01543 6.8e-129 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KHBLGEKB_01544 1.64e-204 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
KHBLGEKB_01546 3.54e-167 - - - L - - - Phage integrase, N-terminal SAM-like domain
KHBLGEKB_01548 1.77e-101 - - - OU - - - Serine dehydrogenase proteinase
KHBLGEKB_01551 1.58e-75 - - - - - - - -
KHBLGEKB_01552 3.76e-82 - - - S - - - Bacterial PH domain
KHBLGEKB_01553 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
KHBLGEKB_01554 1.28e-154 - - - - - - - -
KHBLGEKB_01555 8.32e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHBLGEKB_01556 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KHBLGEKB_01557 1.16e-145 xylR - - K ko:K02529 - ko00000,ko03000 purine nucleotide biosynthetic process
KHBLGEKB_01558 2.16e-122 lemA - - S ko:K03744 - ko00000 LemA family
KHBLGEKB_01559 0.0 - - - S - - - Predicted membrane protein (DUF2207)
KHBLGEKB_01560 5.25e-94 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
KHBLGEKB_01561 3.66e-241 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHBLGEKB_01562 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHBLGEKB_01563 1.36e-125 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
KHBLGEKB_01564 1.26e-55 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
KHBLGEKB_01565 2.79e-213 - - - C - - - Oxidoreductase, aldo keto reductase family protein
KHBLGEKB_01566 2.86e-117 - - - L - - - Transposase and inactivated derivatives IS30 family
KHBLGEKB_01567 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
KHBLGEKB_01568 7.85e-241 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
KHBLGEKB_01569 9.04e-186 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KHBLGEKB_01570 2.23e-164 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHBLGEKB_01571 7.09e-120 - - - D - - - nuclear chromosome segregation
KHBLGEKB_01572 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KHBLGEKB_01573 2.9e-231 - - - L - - - Excalibur calcium-binding domain
KHBLGEKB_01574 8.01e-277 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KHBLGEKB_01575 6.65e-314 - - - EGP - - - Major Facilitator Superfamily
KHBLGEKB_01576 1.71e-138 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KHBLGEKB_01577 4.85e-185 istB - - L - - - IstB-like ATP binding protein
KHBLGEKB_01578 7.82e-278 - - - L - - - PFAM Integrase catalytic
KHBLGEKB_01579 2.11e-69 - - - L - - - PFAM Integrase catalytic
KHBLGEKB_01580 1.55e-141 - - - M - - - Glycosyltransferase like family 2
KHBLGEKB_01581 1.59e-91 - - GT2 S ko:K12992 ko02025,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyltransferase like family 2
KHBLGEKB_01582 3.38e-136 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 transferase activity, transferring glycosyl groups
KHBLGEKB_01583 1.24e-109 - - - M - - - Polysaccharide pyruvyl transferase
KHBLGEKB_01584 1.96e-132 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KHBLGEKB_01585 6.84e-96 rgpC - - GM ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
KHBLGEKB_01586 1.4e-203 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHBLGEKB_01587 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KHBLGEKB_01588 3.21e-255 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHBLGEKB_01589 2.86e-144 - - - L - - - Transposase, Mutator family
KHBLGEKB_01590 6.46e-27 - - - - - - - -
KHBLGEKB_01591 5.24e-298 - - - H - - - Flavin containing amine oxidoreductase
KHBLGEKB_01592 1.26e-268 - - - M - - - Glycosyl hydrolases family 25
KHBLGEKB_01593 2.43e-40 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
KHBLGEKB_01594 3.55e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHBLGEKB_01595 1.79e-79 - - - T - - - protein histidine kinase activity
KHBLGEKB_01596 1.05e-114 - - - K - - - LytTr DNA-binding domain
KHBLGEKB_01597 1.22e-63 - - - S - - - Protein of unknown function (DUF3073)
KHBLGEKB_01598 1.2e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KHBLGEKB_01599 4.09e-249 - - - S - - - Protein conserved in bacteria
KHBLGEKB_01600 1.3e-215 - - - L - - - Transposase and inactivated derivatives IS30 family
KHBLGEKB_01601 7.63e-228 - - - S - - - Amidohydrolase family
KHBLGEKB_01602 0.0 - - - S - - - Threonine/Serine exporter, ThrE
KHBLGEKB_01603 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KHBLGEKB_01604 1.95e-308 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
KHBLGEKB_01605 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
KHBLGEKB_01606 1.01e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
KHBLGEKB_01607 6.08e-154 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KHBLGEKB_01608 2.1e-67 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHBLGEKB_01609 3.36e-306 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
KHBLGEKB_01610 9.86e-241 - - - EG - - - EamA-like transporter family
KHBLGEKB_01611 2.68e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KHBLGEKB_01612 2.08e-175 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
KHBLGEKB_01613 0.0 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KHBLGEKB_01614 1.49e-54 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KHBLGEKB_01615 1.03e-100 ulaC 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHBLGEKB_01616 4.91e-242 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHBLGEKB_01618 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
KHBLGEKB_01621 0.0 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 arabinose metabolic process
KHBLGEKB_01622 9.15e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHBLGEKB_01623 3e-158 gntR - - K - - - FCD
KHBLGEKB_01624 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KHBLGEKB_01628 8.24e-21 - - - K - - - Helix-turn-helix domain
KHBLGEKB_01629 2.73e-19 - - - S - - - Domain of unknown function (DUF4160)
KHBLGEKB_01630 2.87e-56 - - - S - - - Protein of unknown function (DUF2442)
KHBLGEKB_01631 9.05e-12 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHBLGEKB_01632 4.38e-289 - - - I - - - Serine aminopeptidase, S33
KHBLGEKB_01633 4.42e-238 - - - K - - - Periplasmic binding protein domain
KHBLGEKB_01634 4.34e-240 - - - G - - - Glycosyl hydrolases family 43
KHBLGEKB_01636 1.44e-104 - - - S - - - Transmembrane domain of unknown function (DUF3566)
KHBLGEKB_01637 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHBLGEKB_01638 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHBLGEKB_01639 5.54e-125 - - - S - - - Protein of unknown function (DUF721)
KHBLGEKB_01640 1.79e-304 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHBLGEKB_01641 1.15e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KHBLGEKB_01642 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHBLGEKB_01643 3.88e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
KHBLGEKB_01644 2.02e-225 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
KHBLGEKB_01645 4.15e-120 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
KHBLGEKB_01646 4.29e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
KHBLGEKB_01647 3.68e-230 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
KHBLGEKB_01648 1.7e-313 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KHBLGEKB_01649 6.8e-259 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHBLGEKB_01650 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
KHBLGEKB_01651 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
KHBLGEKB_01652 0.0 pccB - - I - - - Carboxyl transferase domain
KHBLGEKB_01653 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
KHBLGEKB_01654 2.14e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KHBLGEKB_01655 4.55e-194 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
KHBLGEKB_01656 0.0 - - - - - - - -
KHBLGEKB_01657 8.27e-187 - - - QT - - - PucR C-terminal helix-turn-helix domain
KHBLGEKB_01658 1.06e-166 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KHBLGEKB_01659 1.39e-66 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KHBLGEKB_01660 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHBLGEKB_01661 2.73e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHBLGEKB_01662 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHBLGEKB_01663 8.04e-192 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHBLGEKB_01664 7.5e-98 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHBLGEKB_01665 1.21e-40 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHBLGEKB_01667 3.54e-188 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KHBLGEKB_01668 2.94e-265 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHBLGEKB_01670 8.85e-47 - - - - - - - -
KHBLGEKB_01671 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
KHBLGEKB_01672 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
KHBLGEKB_01673 1.13e-118 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KHBLGEKB_01675 8.19e-134 mntP - - P - - - Probably functions as a manganese efflux pump
KHBLGEKB_01676 5.6e-170 - - - - - - - -
KHBLGEKB_01677 4.39e-172 glnR - - KT - - - Transcriptional regulatory protein, C terminal
KHBLGEKB_01678 1.16e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHBLGEKB_01679 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KHBLGEKB_01680 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KHBLGEKB_01681 0.0 - - - S - - - domain protein
KHBLGEKB_01682 9.37e-96 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
KHBLGEKB_01683 1.56e-109 lrp_3 - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
KHBLGEKB_01684 8.37e-298 - 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
KHBLGEKB_01685 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KHBLGEKB_01686 0.0 - - - H - - - Flavin containing amine oxidoreductase
KHBLGEKB_01688 6.51e-69 - - - S - - - Protein of unknown function (DUF2469)
KHBLGEKB_01689 1.96e-251 - - - J - - - Acetyltransferase (GNAT) domain
KHBLGEKB_01690 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHBLGEKB_01691 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KHBLGEKB_01692 3.33e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHBLGEKB_01694 7.99e-73 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KHBLGEKB_01695 1.17e-75 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KHBLGEKB_01696 2.26e-212 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
KHBLGEKB_01697 3.51e-164 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHBLGEKB_01698 2.51e-298 rmuC - - S ko:K09760 - ko00000 RmuC family
KHBLGEKB_01699 6.68e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
KHBLGEKB_01700 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
KHBLGEKB_01701 0.0 - - - S ko:K03688 - ko00000 ABC1 family
KHBLGEKB_01702 3.15e-44 - - - S - - - granule-associated protein
KHBLGEKB_01703 1.02e-181 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
KHBLGEKB_01704 0.0 murE - - M - - - Domain of unknown function (DUF1727)
KHBLGEKB_01705 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KHBLGEKB_01706 0.0 dinF - - V - - - MatE
KHBLGEKB_01707 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
KHBLGEKB_01708 2.56e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
KHBLGEKB_01709 2.1e-305 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
KHBLGEKB_01710 6.11e-277 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KHBLGEKB_01712 1.36e-171 icaR - - K - - - Bacterial regulatory proteins, tetR family
KHBLGEKB_01713 6.85e-255 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
KHBLGEKB_01714 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
KHBLGEKB_01715 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
KHBLGEKB_01717 1.82e-67 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KHBLGEKB_01718 6.48e-104 - - - - - - - -
KHBLGEKB_01719 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
KHBLGEKB_01720 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KHBLGEKB_01721 9.34e-106 - - - K - - - Winged helix DNA-binding domain
KHBLGEKB_01723 2.35e-156 - - - L ko:K07483 - ko00000 Integrase core domain
KHBLGEKB_01724 9.77e-51 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
KHBLGEKB_01725 8.89e-111 - - - E - - - IrrE N-terminal-like domain
KHBLGEKB_01727 1.72e-209 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHBLGEKB_01728 2.65e-306 - - - S - - - Putative ABC-transporter type IV
KHBLGEKB_01729 2.24e-103 - - - - - - - -
KHBLGEKB_01730 1.94e-38 - - - Q - - - phosphatase activity
KHBLGEKB_01731 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
KHBLGEKB_01732 2.92e-63 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
KHBLGEKB_01733 5.95e-65 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KHBLGEKB_01734 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHBLGEKB_01735 1.13e-86 - - - S - - - haloacid dehalogenase-like hydrolase
KHBLGEKB_01736 1.5e-167 - - - K ko:K03489,ko:K03710 - ko00000,ko03000 UTRA
KHBLGEKB_01737 8.08e-103 - - - S - - - FMN_bind
KHBLGEKB_01738 2.6e-189 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHBLGEKB_01739 9e-279 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHBLGEKB_01740 2.54e-286 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KHBLGEKB_01741 8.34e-294 - - - S - - - Predicted membrane protein (DUF2318)
KHBLGEKB_01742 4.8e-150 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
KHBLGEKB_01743 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
KHBLGEKB_01745 3.88e-250 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHBLGEKB_01746 4.24e-49 - - - S - - - Fic/DOC family
KHBLGEKB_01747 7.68e-62 - - - S - - - Fic/DOC family
KHBLGEKB_01748 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHBLGEKB_01749 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
KHBLGEKB_01750 8.04e-257 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHBLGEKB_01751 5.19e-273 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KHBLGEKB_01752 4.2e-158 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHBLGEKB_01753 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHBLGEKB_01754 3.23e-251 - - - I - - - PAP2 superfamily
KHBLGEKB_01755 0.0 - - - M - - - PA domain
KHBLGEKB_01756 5.69e-176 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
KHBLGEKB_01757 1.8e-295 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KHBLGEKB_01758 0.0 pbp5 - - M - - - Transglycosylase
KHBLGEKB_01759 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHBLGEKB_01760 0.0 - - - S - - - Calcineurin-like phosphoesterase
KHBLGEKB_01761 1.29e-24 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
KHBLGEKB_01762 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
KHBLGEKB_01763 1.77e-148 - - - - - - - -
KHBLGEKB_01764 7.91e-271 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHBLGEKB_01766 1.42e-126 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
KHBLGEKB_01767 2.29e-176 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
KHBLGEKB_01768 1.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHBLGEKB_01769 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
KHBLGEKB_01770 1.61e-274 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
KHBLGEKB_01771 1.04e-72 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
KHBLGEKB_01772 3.96e-55 - - - S - - - Protein of unknown function (DUF4244)
KHBLGEKB_01773 1.3e-20 - - - NU - - - Type II secretion system (T2SS), protein F
KHBLGEKB_01775 2.62e-157 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
KHBLGEKB_01776 6.74e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
KHBLGEKB_01777 1.34e-196 - - - D - - - bacterial-type flagellum organization
KHBLGEKB_01779 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KHBLGEKB_01780 1.1e-282 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
KHBLGEKB_01781 8.69e-129 - - - - - - - -
KHBLGEKB_01782 2.88e-25 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
KHBLGEKB_01783 9.1e-39 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KHBLGEKB_01784 7.47e-267 - - - S - - - Glycosyltransferase, group 2 family protein
KHBLGEKB_01785 0.0 - - - - - - - -
KHBLGEKB_01786 1.99e-36 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
KHBLGEKB_01787 5.53e-211 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KHBLGEKB_01788 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
KHBLGEKB_01789 0.0 - - - H - - - Protein of unknown function (DUF4012)
KHBLGEKB_01790 0.0 - - - V - - - ABC transporter permease
KHBLGEKB_01791 3.15e-259 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KHBLGEKB_01792 3.28e-176 - - - T ko:K06950 - ko00000 HD domain
KHBLGEKB_01793 3.34e-211 - - - S - - - Glutamine amidotransferase domain
KHBLGEKB_01795 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KHBLGEKB_01796 1.29e-235 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
KHBLGEKB_01797 0.0 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
KHBLGEKB_01799 1.2e-107 - - - K - - - Transcriptional regulator
KHBLGEKB_01800 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHBLGEKB_01801 7.68e-170 - - - - - - - -
KHBLGEKB_01802 1.6e-83 - - - - - - - -
KHBLGEKB_01803 5.14e-219 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHBLGEKB_01804 2.18e-162 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
KHBLGEKB_01806 1.17e-171 - - - S - - - HAD hydrolase, family IA, variant 3
KHBLGEKB_01807 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR Asp-box repeat
KHBLGEKB_01808 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
KHBLGEKB_01809 6.42e-112 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
KHBLGEKB_01810 1.35e-236 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
KHBLGEKB_01811 8.46e-88 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHBLGEKB_01812 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KHBLGEKB_01813 0.0 strK 3.1.3.1, 3.1.3.39 - P ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase homologues
KHBLGEKB_01814 2.63e-241 - - - K - - - Psort location Cytoplasmic, score
KHBLGEKB_01816 3.05e-179 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
KHBLGEKB_01817 5.82e-89 - - - S - - - Protein of unknown function (DUF4235)
KHBLGEKB_01818 9.16e-182 nfrA - - C - - - Nitroreductase family
KHBLGEKB_01819 2.45e-61 - - - - - - - -
KHBLGEKB_01821 1.66e-128 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KHBLGEKB_01822 4.21e-242 - - - S ko:K06889 - ko00000 alpha beta
KHBLGEKB_01823 3.47e-306 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KHBLGEKB_01824 1.08e-58 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
KHBLGEKB_01825 5.66e-258 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
KHBLGEKB_01826 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
KHBLGEKB_01827 1.45e-236 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHBLGEKB_01828 0.0 corC - - S - - - CBS domain
KHBLGEKB_01829 1.82e-130 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHBLGEKB_01830 1.49e-253 phoH - - T ko:K06217 - ko00000 PhoH-like protein
KHBLGEKB_01831 1.37e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
KHBLGEKB_01832 2.18e-175 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KHBLGEKB_01834 1.78e-208 spoU2 - - J - - - SpoU rRNA Methylase family
KHBLGEKB_01835 1.42e-308 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHBLGEKB_01836 2.56e-141 - - - S - - - Iron-sulfur cluster assembly protein
KHBLGEKB_01837 4.14e-132 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
KHBLGEKB_01838 3.62e-306 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHBLGEKB_01839 2.13e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
KHBLGEKB_01840 2.92e-298 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
KHBLGEKB_01841 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
KHBLGEKB_01842 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KHBLGEKB_01843 1.76e-05 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
KHBLGEKB_01844 3.46e-154 - - - K - - - helix_turn_helix, Lux Regulon
KHBLGEKB_01845 4.78e-138 - - - - - - - -
KHBLGEKB_01846 1.6e-103 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
KHBLGEKB_01847 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KHBLGEKB_01848 4.5e-280 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHBLGEKB_01849 4.35e-68 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
KHBLGEKB_01850 4.48e-247 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHBLGEKB_01851 6.58e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHBLGEKB_01852 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHBLGEKB_01853 7.33e-50 - - - - - - - -
KHBLGEKB_01854 4.03e-85 - - - S - - - Bacterial protein of unknown function (DUF948)
KHBLGEKB_01855 5.11e-172 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
KHBLGEKB_01856 0.0 - - - I - - - Psort location CytoplasmicMembrane, score 9.99
KHBLGEKB_01857 1.83e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHBLGEKB_01858 1.29e-170 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KHBLGEKB_01859 9.28e-272 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHBLGEKB_01860 1e-83 - - - S - - - Domain of unknown function (DUF4418)
KHBLGEKB_01861 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KHBLGEKB_01862 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
KHBLGEKB_01863 6.52e-139 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KHBLGEKB_01864 1.67e-307 pbuX - - F ko:K03458 - ko00000 Permease family
KHBLGEKB_01866 1.66e-61 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHBLGEKB_01867 2.02e-141 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHBLGEKB_01869 4.2e-145 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
KHBLGEKB_01870 9.3e-53 - - - - - - - -
KHBLGEKB_01871 5.58e-33 - - - S - - - Adenine-specific methyltransferase EcoRI
KHBLGEKB_01872 1.05e-148 tnp3521a2 - - L - - - Integrase core domain
KHBLGEKB_01873 1.2e-83 - - - D - - - MobA/MobL family
KHBLGEKB_01874 1.18e-99 - - - - - - - -
KHBLGEKB_01876 1.7e-185 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
KHBLGEKB_01877 5.39e-296 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
KHBLGEKB_01878 1.12e-109 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KHBLGEKB_01879 2.7e-184 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
KHBLGEKB_01880 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
KHBLGEKB_01881 6.04e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
KHBLGEKB_01882 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
KHBLGEKB_01883 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
KHBLGEKB_01885 2.19e-223 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHBLGEKB_01886 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
KHBLGEKB_01887 7.99e-193 - - - - - - - -
KHBLGEKB_01888 5.45e-232 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KHBLGEKB_01889 1.52e-309 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHBLGEKB_01890 0.0 - - - S - - - LPXTG-motif cell wall anchor domain protein
KHBLGEKB_01891 4.46e-132 - - - L - - - Helix-turn-helix domain
KHBLGEKB_01892 2.18e-269 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHBLGEKB_01893 3.11e-220 - - - K - - - Psort location Cytoplasmic, score
KHBLGEKB_01898 0.0 - - - M - - - Conserved repeat domain
KHBLGEKB_01899 3.18e-160 mutT4 - - L - - - Belongs to the Nudix hydrolase family
KHBLGEKB_01900 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
KHBLGEKB_01901 6.94e-146 - - - S - - - LytR cell envelope-related transcriptional attenuator
KHBLGEKB_01902 2.19e-212 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHBLGEKB_01903 8.92e-218 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KHBLGEKB_01904 1.08e-276 rpfB - - S ko:K21688 - ko00000 G5
KHBLGEKB_01906 2.59e-201 - - - O - - - Thioredoxin
KHBLGEKB_01907 0.0 - - - KLT - - - Protein tyrosine kinase
KHBLGEKB_01908 4.83e-164 - - - L - - - Phage integrase family
KHBLGEKB_01909 6.85e-92 - - - - - - - -
KHBLGEKB_01910 7.2e-200 - - - S ko:K14623 - ko00000,ko03400 SOS response
KHBLGEKB_01911 2.3e-88 - - - - - - - -
KHBLGEKB_01912 8.19e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
KHBLGEKB_01915 9.11e-28 - - - - - - - -
KHBLGEKB_01917 3.82e-70 - - - - - - - -
KHBLGEKB_01921 4.93e-82 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 single-stranded DNA-binding protein
KHBLGEKB_01922 4.46e-62 - - - - - - - -
KHBLGEKB_01924 1.44e-226 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 ParB-like nuclease domain
KHBLGEKB_01926 5.37e-64 - - - V - - - HNH endonuclease
KHBLGEKB_01927 2.77e-89 - - - A ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
KHBLGEKB_01933 4.15e-63 - - - - - - - -
KHBLGEKB_01936 2.05e-21 - - - K - - - Helix-turn-helix domain
KHBLGEKB_01941 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
KHBLGEKB_01942 2.59e-198 - - - S - - - Domain of unknown function (DUF4357)
KHBLGEKB_01943 2e-41 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)