ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NEKGAFBM_00001 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
NEKGAFBM_00002 4.09e-253 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEKGAFBM_00003 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
NEKGAFBM_00004 0.0 - - - L - - - MutS domain V
NEKGAFBM_00005 3.85e-234 ykoT - - M - - - Glycosyl transferase family 2
NEKGAFBM_00006 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEKGAFBM_00007 2.24e-87 - - - S - - - NUDIX domain
NEKGAFBM_00008 0.0 - - - S - - - membrane
NEKGAFBM_00009 4.26e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NEKGAFBM_00010 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NEKGAFBM_00011 2.08e-284 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NEKGAFBM_00012 1.23e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NEKGAFBM_00013 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
NEKGAFBM_00014 3.39e-138 - - - - - - - -
NEKGAFBM_00015 2.71e-150 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
NEKGAFBM_00016 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_00017 5.19e-309 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NEKGAFBM_00018 0.0 - - - - - - - -
NEKGAFBM_00019 4.75e-80 - - - - - - - -
NEKGAFBM_00020 3.36e-248 - - - S - - - Fn3-like domain
NEKGAFBM_00021 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
NEKGAFBM_00022 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
NEKGAFBM_00023 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEKGAFBM_00024 7.9e-72 - - - - - - - -
NEKGAFBM_00025 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NEKGAFBM_00026 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_00027 8.17e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_00028 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
NEKGAFBM_00029 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEKGAFBM_00030 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
NEKGAFBM_00031 1.69e-144 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEKGAFBM_00032 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NEKGAFBM_00033 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NEKGAFBM_00034 3.04e-29 - - - S - - - Virus attachment protein p12 family
NEKGAFBM_00035 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NEKGAFBM_00036 1.67e-46 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
NEKGAFBM_00037 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NEKGAFBM_00038 8.63e-310 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NEKGAFBM_00039 1.83e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEKGAFBM_00040 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NEKGAFBM_00041 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NEKGAFBM_00042 4.07e-60 - - - S - - - Iron-sulfur cluster assembly protein
NEKGAFBM_00043 1.04e-141 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NEKGAFBM_00044 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NEKGAFBM_00045 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEKGAFBM_00046 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NEKGAFBM_00047 3.88e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEKGAFBM_00048 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEKGAFBM_00049 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NEKGAFBM_00050 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NEKGAFBM_00051 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEKGAFBM_00052 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEKGAFBM_00053 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NEKGAFBM_00054 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEKGAFBM_00055 2.76e-74 - - - - - - - -
NEKGAFBM_00056 8.2e-306 - - - L ko:K07478 - ko00000 AAA C-terminal domain
NEKGAFBM_00057 7.78e-81 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NEKGAFBM_00058 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
NEKGAFBM_00059 2.39e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NEKGAFBM_00060 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
NEKGAFBM_00061 1.81e-113 - - - - - - - -
NEKGAFBM_00062 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NEKGAFBM_00063 1.09e-275 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NEKGAFBM_00064 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NEKGAFBM_00065 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEKGAFBM_00066 1.71e-149 yqeK - - H - - - Hydrolase, HD family
NEKGAFBM_00067 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEKGAFBM_00068 6.65e-180 yqeM - - Q - - - Methyltransferase
NEKGAFBM_00069 3.55e-279 ylbM - - S - - - Belongs to the UPF0348 family
NEKGAFBM_00070 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NEKGAFBM_00071 1.3e-125 - - - S - - - Peptidase propeptide and YPEB domain
NEKGAFBM_00072 8.93e-223 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEKGAFBM_00073 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEKGAFBM_00074 3.12e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NEKGAFBM_00075 1.38e-155 csrR - - K - - - response regulator
NEKGAFBM_00076 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEKGAFBM_00077 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NEKGAFBM_00078 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NEKGAFBM_00079 2.36e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NEKGAFBM_00080 1.21e-129 - - - S - - - SdpI/YhfL protein family
NEKGAFBM_00081 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEKGAFBM_00082 5.58e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NEKGAFBM_00083 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEKGAFBM_00084 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEKGAFBM_00085 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
NEKGAFBM_00086 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEKGAFBM_00087 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEKGAFBM_00088 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NEKGAFBM_00089 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NEKGAFBM_00090 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEKGAFBM_00091 9.72e-146 - - - S - - - membrane
NEKGAFBM_00092 5.72e-99 - - - K - - - LytTr DNA-binding domain
NEKGAFBM_00093 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
NEKGAFBM_00094 0.0 - - - S - - - membrane
NEKGAFBM_00095 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NEKGAFBM_00096 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NEKGAFBM_00097 3.24e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NEKGAFBM_00098 2.47e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
NEKGAFBM_00099 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NEKGAFBM_00100 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NEKGAFBM_00101 5.43e-140 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NEKGAFBM_00102 6.68e-89 yqhL - - P - - - Rhodanese-like protein
NEKGAFBM_00103 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NEKGAFBM_00104 1.83e-177 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
NEKGAFBM_00105 2.29e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEKGAFBM_00106 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NEKGAFBM_00107 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NEKGAFBM_00108 1.77e-205 - - - - - - - -
NEKGAFBM_00109 1.34e-232 - - - - - - - -
NEKGAFBM_00110 3.55e-127 - - - S - - - Protein conserved in bacteria
NEKGAFBM_00111 1.87e-74 - - - - - - - -
NEKGAFBM_00112 2.97e-41 - - - - - - - -
NEKGAFBM_00115 9.81e-27 - - - - - - - -
NEKGAFBM_00116 6.69e-124 - - - K - - - Transcriptional regulator
NEKGAFBM_00117 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NEKGAFBM_00118 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NEKGAFBM_00119 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NEKGAFBM_00120 6.04e-249 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NEKGAFBM_00121 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEKGAFBM_00122 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NEKGAFBM_00123 5.46e-89 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEKGAFBM_00124 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEKGAFBM_00125 3.99e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEKGAFBM_00126 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEKGAFBM_00127 5.49e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEKGAFBM_00128 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NEKGAFBM_00129 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NEKGAFBM_00130 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NEKGAFBM_00131 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_00132 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEKGAFBM_00133 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEKGAFBM_00134 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKGAFBM_00135 2.38e-72 - - - - - - - -
NEKGAFBM_00136 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NEKGAFBM_00137 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEKGAFBM_00138 5.04e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NEKGAFBM_00139 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEKGAFBM_00140 1.49e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEKGAFBM_00141 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NEKGAFBM_00142 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NEKGAFBM_00143 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NEKGAFBM_00144 9.9e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEKGAFBM_00145 2.22e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NEKGAFBM_00146 2.61e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NEKGAFBM_00147 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NEKGAFBM_00148 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
NEKGAFBM_00149 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NEKGAFBM_00150 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NEKGAFBM_00151 1.79e-243 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NEKGAFBM_00152 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEKGAFBM_00153 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEKGAFBM_00154 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NEKGAFBM_00155 7.71e-298 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEKGAFBM_00156 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NEKGAFBM_00157 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEKGAFBM_00158 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NEKGAFBM_00159 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NEKGAFBM_00160 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEKGAFBM_00161 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NEKGAFBM_00162 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEKGAFBM_00163 1.03e-66 - - - - - - - -
NEKGAFBM_00164 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEKGAFBM_00165 1.1e-112 - - - - - - - -
NEKGAFBM_00166 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NEKGAFBM_00167 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
NEKGAFBM_00169 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
NEKGAFBM_00170 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
NEKGAFBM_00171 1.42e-224 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NEKGAFBM_00172 6.06e-159 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NEKGAFBM_00173 1.51e-140 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NEKGAFBM_00174 1.79e-287 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEKGAFBM_00175 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEKGAFBM_00176 1.45e-126 entB - - Q - - - Isochorismatase family
NEKGAFBM_00177 3.53e-227 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
NEKGAFBM_00178 1.95e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
NEKGAFBM_00179 1.62e-276 - - - E - - - glutamate:sodium symporter activity
NEKGAFBM_00180 1.38e-273 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
NEKGAFBM_00181 1.56e-251 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NEKGAFBM_00182 2.12e-77 - - - S - - - Protein of unknown function (DUF1648)
NEKGAFBM_00183 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEKGAFBM_00184 8.02e-230 yneE - - K - - - Transcriptional regulator
NEKGAFBM_00185 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NEKGAFBM_00186 1.97e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEKGAFBM_00187 6.16e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEKGAFBM_00188 2.97e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NEKGAFBM_00189 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NEKGAFBM_00190 5.38e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEKGAFBM_00191 5.25e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEKGAFBM_00192 7.23e-93 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NEKGAFBM_00193 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NEKGAFBM_00194 2.62e-202 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEKGAFBM_00195 1.96e-178 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NEKGAFBM_00196 5.4e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NEKGAFBM_00197 1.01e-128 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NEKGAFBM_00198 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NEKGAFBM_00199 1.07e-206 - - - K - - - LysR substrate binding domain
NEKGAFBM_00200 4.94e-114 ykhA - - I - - - Thioesterase superfamily
NEKGAFBM_00201 2.66e-247 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEKGAFBM_00202 2.46e-120 - - - K - - - transcriptional regulator
NEKGAFBM_00203 0.0 - - - EGP - - - Major Facilitator
NEKGAFBM_00204 6.56e-193 - - - O - - - Band 7 protein
NEKGAFBM_00205 8.14e-47 - - - L - - - Pfam:Integrase_AP2
NEKGAFBM_00209 1.19e-13 - - - - - - - -
NEKGAFBM_00211 2.1e-71 - - - - - - - -
NEKGAFBM_00212 1.42e-39 - - - - - - - -
NEKGAFBM_00213 1.69e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NEKGAFBM_00214 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
NEKGAFBM_00215 3.16e-64 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
NEKGAFBM_00216 2.05e-55 - - - - - - - -
NEKGAFBM_00217 4.98e-107 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
NEKGAFBM_00218 3.05e-99 - - - T - - - Belongs to the universal stress protein A family
NEKGAFBM_00219 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
NEKGAFBM_00220 1.79e-211 - - - I - - - Diacylglycerol kinase catalytic domain
NEKGAFBM_00221 1.51e-48 - - - - - - - -
NEKGAFBM_00222 5.79e-21 - - - - - - - -
NEKGAFBM_00223 2.22e-55 - - - S - - - transglycosylase associated protein
NEKGAFBM_00224 4e-40 - - - S - - - CsbD-like
NEKGAFBM_00225 1.06e-53 - - - - - - - -
NEKGAFBM_00226 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEKGAFBM_00227 4.87e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NEKGAFBM_00228 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEKGAFBM_00229 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
NEKGAFBM_00230 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
NEKGAFBM_00231 4.35e-67 - - - - - - - -
NEKGAFBM_00232 2.12e-57 - - - - - - - -
NEKGAFBM_00233 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEKGAFBM_00234 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NEKGAFBM_00235 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NEKGAFBM_00236 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NEKGAFBM_00237 2.06e-158 - - - S - - - Domain of unknown function (DUF4767)
NEKGAFBM_00238 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NEKGAFBM_00239 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NEKGAFBM_00240 9.23e-245 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NEKGAFBM_00241 8.61e-251 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NEKGAFBM_00242 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NEKGAFBM_00243 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NEKGAFBM_00244 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NEKGAFBM_00245 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NEKGAFBM_00246 2.53e-107 ypmB - - S - - - protein conserved in bacteria
NEKGAFBM_00247 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NEKGAFBM_00248 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NEKGAFBM_00249 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
NEKGAFBM_00251 9.85e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEKGAFBM_00252 2.45e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEKGAFBM_00253 5.51e-204 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NEKGAFBM_00254 1.31e-109 - - - T - - - Universal stress protein family
NEKGAFBM_00255 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKGAFBM_00256 4.86e-235 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEKGAFBM_00257 8.37e-231 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NEKGAFBM_00258 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NEKGAFBM_00259 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NEKGAFBM_00260 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
NEKGAFBM_00261 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NEKGAFBM_00263 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NEKGAFBM_00264 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEKGAFBM_00265 3.65e-308 - - - P - - - Major Facilitator Superfamily
NEKGAFBM_00266 1.7e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NEKGAFBM_00267 2.26e-95 - - - S - - - SnoaL-like domain
NEKGAFBM_00268 1.2e-84 - - - M - - - Glycosyltransferase, group 2 family protein
NEKGAFBM_00269 3.91e-149 - - - M - - - Glycosyltransferase, group 2 family protein
NEKGAFBM_00270 3.32e-265 mccF - - V - - - LD-carboxypeptidase
NEKGAFBM_00271 1.64e-62 - - - K - - - Acetyltransferase (GNAT) domain
NEKGAFBM_00272 5.01e-311 - - - M ko:K07273 - ko00000 hydrolase, family 25
NEKGAFBM_00273 1.44e-234 - - - V - - - LD-carboxypeptidase
NEKGAFBM_00274 8.41e-97 XK27_05710 - - K - - - Acetyltransferase (GNAT) domain
NEKGAFBM_00275 5.46e-157 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NEKGAFBM_00276 1.9e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKGAFBM_00277 6.79e-249 - - - - - - - -
NEKGAFBM_00278 3.69e-187 - - - S - - - hydrolase activity, acting on ester bonds
NEKGAFBM_00279 2.44e-267 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
NEKGAFBM_00280 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NEKGAFBM_00281 5.89e-81 esbA - - S - - - Family of unknown function (DUF5322)
NEKGAFBM_00282 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NEKGAFBM_00283 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEKGAFBM_00284 1.96e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEKGAFBM_00285 1.1e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEKGAFBM_00286 4.89e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
NEKGAFBM_00287 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NEKGAFBM_00288 0.0 - - - S - - - Bacterial membrane protein, YfhO
NEKGAFBM_00289 1.66e-144 - - - G - - - Phosphoglycerate mutase family
NEKGAFBM_00290 6.38e-92 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NEKGAFBM_00292 7.51e-166 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
NEKGAFBM_00293 8.49e-92 - - - S - - - LuxR family transcriptional regulator
NEKGAFBM_00294 2.31e-174 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
NEKGAFBM_00296 5.37e-117 - - - F - - - NUDIX domain
NEKGAFBM_00297 2.42e-71 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_00298 0.0 FbpA - - K - - - Fibronectin-binding protein
NEKGAFBM_00299 1.97e-87 - - - K - - - Transcriptional regulator
NEKGAFBM_00300 1.11e-205 - - - S - - - EDD domain protein, DegV family
NEKGAFBM_00301 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
NEKGAFBM_00302 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
NEKGAFBM_00303 3.03e-40 - - - - - - - -
NEKGAFBM_00304 2.37e-65 - - - - - - - -
NEKGAFBM_00305 2.82e-190 - - - C - - - Domain of unknown function (DUF4931)
NEKGAFBM_00306 6e-268 pmrB - - EGP - - - Major Facilitator Superfamily
NEKGAFBM_00308 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
NEKGAFBM_00309 6.02e-166 yejC - - S - - - Protein of unknown function (DUF1003)
NEKGAFBM_00310 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
NEKGAFBM_00311 2.14e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NEKGAFBM_00312 2.79e-181 - - - - - - - -
NEKGAFBM_00313 7.79e-78 - - - - - - - -
NEKGAFBM_00314 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NEKGAFBM_00315 7.87e-289 - - - - - - - -
NEKGAFBM_00316 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NEKGAFBM_00317 1.47e-243 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NEKGAFBM_00318 1.66e-249 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEKGAFBM_00319 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEKGAFBM_00320 1.34e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEKGAFBM_00321 1.6e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEKGAFBM_00322 7.91e-305 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NEKGAFBM_00323 3.81e-64 - - - - - - - -
NEKGAFBM_00324 1.96e-309 - - - M - - - Glycosyl transferase family group 2
NEKGAFBM_00325 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEKGAFBM_00326 2.95e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
NEKGAFBM_00327 1.07e-43 - - - S - - - YozE SAM-like fold
NEKGAFBM_00328 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEKGAFBM_00329 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NEKGAFBM_00330 3.91e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NEKGAFBM_00331 3.82e-228 - - - K - - - Transcriptional regulator
NEKGAFBM_00332 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEKGAFBM_00333 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEKGAFBM_00334 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NEKGAFBM_00335 3.64e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NEKGAFBM_00336 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NEKGAFBM_00337 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NEKGAFBM_00338 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NEKGAFBM_00339 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NEKGAFBM_00340 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEKGAFBM_00341 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NEKGAFBM_00342 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEKGAFBM_00343 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NEKGAFBM_00344 5.13e-292 XK27_05470 - - E - - - Methionine synthase
NEKGAFBM_00345 1.22e-219 cpsY - - K - - - Transcriptional regulator, LysR family
NEKGAFBM_00346 1.27e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
NEKGAFBM_00347 1.75e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NEKGAFBM_00348 4.11e-251 XK27_00915 - - C - - - Luciferase-like monooxygenase
NEKGAFBM_00349 0.0 qacA - - EGP - - - Major Facilitator
NEKGAFBM_00350 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NEKGAFBM_00351 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
NEKGAFBM_00352 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NEKGAFBM_00353 1.02e-209 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
NEKGAFBM_00354 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
NEKGAFBM_00355 3e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NEKGAFBM_00356 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEKGAFBM_00357 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_00358 6.46e-109 - - - - - - - -
NEKGAFBM_00359 3.65e-291 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NEKGAFBM_00360 5.66e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEKGAFBM_00361 9.1e-193 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NEKGAFBM_00362 7.1e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NEKGAFBM_00363 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NEKGAFBM_00364 4.84e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NEKGAFBM_00365 1.15e-280 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NEKGAFBM_00366 2.1e-150 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NEKGAFBM_00367 1.25e-39 - - - M - - - Lysin motif
NEKGAFBM_00368 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NEKGAFBM_00369 2.78e-251 - - - S - - - Helix-turn-helix domain
NEKGAFBM_00370 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEKGAFBM_00371 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NEKGAFBM_00372 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NEKGAFBM_00373 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NEKGAFBM_00374 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEKGAFBM_00375 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NEKGAFBM_00376 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
NEKGAFBM_00377 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
NEKGAFBM_00378 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NEKGAFBM_00379 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NEKGAFBM_00380 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NEKGAFBM_00381 2.02e-39 - - - S - - - Protein of unknown function (DUF2929)
NEKGAFBM_00382 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEKGAFBM_00383 3.17e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NEKGAFBM_00384 6.55e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NEKGAFBM_00385 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NEKGAFBM_00386 4.8e-293 - - - M - - - O-Antigen ligase
NEKGAFBM_00387 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NEKGAFBM_00388 3.85e-209 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_00389 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEKGAFBM_00390 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NEKGAFBM_00391 1.94e-83 - - - P - - - Rhodanese Homology Domain
NEKGAFBM_00392 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEKGAFBM_00393 5.78e-268 - - - - - - - -
NEKGAFBM_00394 6.09e-281 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
NEKGAFBM_00395 1.51e-232 - - - C - - - Zinc-binding dehydrogenase
NEKGAFBM_00396 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
NEKGAFBM_00397 4.44e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEKGAFBM_00398 8.87e-305 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
NEKGAFBM_00399 4.38e-102 - - - K - - - Transcriptional regulator
NEKGAFBM_00400 6.46e-265 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NEKGAFBM_00401 6.66e-235 tanA - - S - - - alpha beta
NEKGAFBM_00402 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEKGAFBM_00403 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NEKGAFBM_00404 7.25e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NEKGAFBM_00405 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
NEKGAFBM_00406 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
NEKGAFBM_00407 5.7e-146 - - - GM - - - epimerase
NEKGAFBM_00408 0.0 - - - S - - - Zinc finger, swim domain protein
NEKGAFBM_00409 6.13e-105 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_00410 1.12e-273 - - - S - - - membrane
NEKGAFBM_00411 1.55e-07 - - - K - - - transcriptional regulator
NEKGAFBM_00412 8.13e-90 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEKGAFBM_00413 5.17e-30 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_00414 7.51e-147 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
NEKGAFBM_00415 1.63e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NEKGAFBM_00416 3.69e-169 - - - K - - - Helix-turn-helix domain, rpiR family
NEKGAFBM_00417 2.63e-206 - - - S - - - Alpha beta hydrolase
NEKGAFBM_00418 3.55e-146 - - - GM - - - NmrA-like family
NEKGAFBM_00419 2.12e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
NEKGAFBM_00420 5.72e-207 - - - K - - - Transcriptional regulator
NEKGAFBM_00421 9.29e-222 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NEKGAFBM_00423 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEKGAFBM_00424 1.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NEKGAFBM_00425 2.08e-265 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEKGAFBM_00426 1.27e-174 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NEKGAFBM_00427 3.43e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_00429 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEKGAFBM_00430 3.89e-94 - - - K - - - MarR family
NEKGAFBM_00431 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
NEKGAFBM_00432 0.000138 yjdF - - S - - - Protein of unknown function (DUF2992)
NEKGAFBM_00433 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_00434 2.11e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEKGAFBM_00435 1.74e-252 - - - - - - - -
NEKGAFBM_00436 2.59e-256 - - - - - - - -
NEKGAFBM_00437 2.45e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_00438 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NEKGAFBM_00439 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEKGAFBM_00440 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEKGAFBM_00441 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NEKGAFBM_00442 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NEKGAFBM_00443 2.33e-188 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NEKGAFBM_00444 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEKGAFBM_00445 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NEKGAFBM_00446 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEKGAFBM_00447 9.71e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NEKGAFBM_00448 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NEKGAFBM_00449 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NEKGAFBM_00450 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NEKGAFBM_00451 3.65e-166 - - - C - - - Enoyl-(Acyl carrier protein) reductase
NEKGAFBM_00452 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NEKGAFBM_00453 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEKGAFBM_00454 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEKGAFBM_00455 2.15e-131 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEKGAFBM_00456 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NEKGAFBM_00457 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NEKGAFBM_00458 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
NEKGAFBM_00459 2.65e-213 - - - G - - - Fructosamine kinase
NEKGAFBM_00460 1.35e-147 yjcF - - J - - - HAD-hyrolase-like
NEKGAFBM_00461 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEKGAFBM_00462 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEKGAFBM_00463 2.56e-76 - - - - - - - -
NEKGAFBM_00464 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEKGAFBM_00465 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NEKGAFBM_00466 1.11e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NEKGAFBM_00467 4.78e-65 - - - - - - - -
NEKGAFBM_00468 1.73e-67 - - - - - - - -
NEKGAFBM_00469 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEKGAFBM_00470 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NEKGAFBM_00471 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEKGAFBM_00472 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NEKGAFBM_00473 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEKGAFBM_00474 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
NEKGAFBM_00475 8.49e-266 pbpX2 - - V - - - Beta-lactamase
NEKGAFBM_00476 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEKGAFBM_00477 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NEKGAFBM_00478 4.52e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEKGAFBM_00479 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEKGAFBM_00480 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NEKGAFBM_00481 7.56e-242 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NEKGAFBM_00482 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEKGAFBM_00483 1.45e-114 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NEKGAFBM_00484 5.99e-246 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NEKGAFBM_00485 6.72e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEKGAFBM_00486 6.65e-121 - - - - - - - -
NEKGAFBM_00487 3.67e-275 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEKGAFBM_00488 0.0 - - - G - - - Major Facilitator
NEKGAFBM_00489 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEKGAFBM_00490 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEKGAFBM_00491 3.28e-63 ylxQ - - J - - - ribosomal protein
NEKGAFBM_00492 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NEKGAFBM_00493 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NEKGAFBM_00494 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NEKGAFBM_00495 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEKGAFBM_00496 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEKGAFBM_00497 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NEKGAFBM_00498 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NEKGAFBM_00499 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEKGAFBM_00500 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEKGAFBM_00501 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NEKGAFBM_00502 1.55e-193 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEKGAFBM_00503 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NEKGAFBM_00504 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
NEKGAFBM_00505 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEKGAFBM_00506 8.37e-66 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NEKGAFBM_00507 3.65e-172 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NEKGAFBM_00508 1.71e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NEKGAFBM_00509 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
NEKGAFBM_00510 7.68e-48 ynzC - - S - - - UPF0291 protein
NEKGAFBM_00511 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEKGAFBM_00512 1.83e-121 - - - - - - - -
NEKGAFBM_00513 6.62e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NEKGAFBM_00514 1.01e-100 - - - - - - - -
NEKGAFBM_00515 3.26e-88 - - - - - - - -
NEKGAFBM_00516 2.3e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
NEKGAFBM_00519 5.32e-12 - - - S - - - Short C-terminal domain
NEKGAFBM_00520 4.86e-233 - - - M - - - Peptidase family S41
NEKGAFBM_00521 2.24e-277 - - - - - - - -
NEKGAFBM_00522 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEKGAFBM_00523 0.0 yhaN - - L - - - AAA domain
NEKGAFBM_00524 5e-293 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
NEKGAFBM_00525 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
NEKGAFBM_00526 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NEKGAFBM_00527 2.43e-18 - - - - - - - -
NEKGAFBM_00528 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NEKGAFBM_00529 9.65e-272 arcT - - E - - - Aminotransferase
NEKGAFBM_00530 3.29e-132 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
NEKGAFBM_00531 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
NEKGAFBM_00532 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEKGAFBM_00533 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
NEKGAFBM_00534 1.1e-70 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
NEKGAFBM_00535 1.14e-191 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
NEKGAFBM_00536 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEKGAFBM_00537 1.02e-285 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_00538 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEKGAFBM_00539 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NEKGAFBM_00540 1.34e-104 - - - S - - - Domain of unknown function (DUF3284)
NEKGAFBM_00541 0.0 celR - - K - - - PRD domain
NEKGAFBM_00542 6.25e-138 - - - - - - - -
NEKGAFBM_00543 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NEKGAFBM_00544 3.81e-105 - - - - - - - -
NEKGAFBM_00545 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NEKGAFBM_00546 7.02e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
NEKGAFBM_00549 1.79e-42 - - - - - - - -
NEKGAFBM_00550 2.69e-316 dinF - - V - - - MatE
NEKGAFBM_00551 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
NEKGAFBM_00552 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
NEKGAFBM_00553 5.68e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
NEKGAFBM_00554 2.24e-146 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NEKGAFBM_00555 7.32e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
NEKGAFBM_00556 0.0 - - - S - - - Protein conserved in bacteria
NEKGAFBM_00557 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NEKGAFBM_00558 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NEKGAFBM_00559 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
NEKGAFBM_00560 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
NEKGAFBM_00561 3.89e-237 - - - - - - - -
NEKGAFBM_00562 9.03e-16 - - - - - - - -
NEKGAFBM_00563 4.29e-87 - - - - - - - -
NEKGAFBM_00566 0.0 uvrA2 - - L - - - ABC transporter
NEKGAFBM_00567 7.12e-62 - - - - - - - -
NEKGAFBM_00568 8.82e-119 - - - - - - - -
NEKGAFBM_00569 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
NEKGAFBM_00570 1.06e-146 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_00571 4.56e-78 - - - - - - - -
NEKGAFBM_00572 5.37e-74 - - - - - - - -
NEKGAFBM_00573 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEKGAFBM_00574 8.83e-285 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEKGAFBM_00575 7.83e-140 - - - - - - - -
NEKGAFBM_00576 1.14e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEKGAFBM_00577 9.36e-205 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NEKGAFBM_00578 1.64e-151 - - - GM - - - NAD(P)H-binding
NEKGAFBM_00579 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
NEKGAFBM_00580 6.68e-196 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEKGAFBM_00582 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
NEKGAFBM_00583 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_00584 4.24e-163 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
NEKGAFBM_00586 7.61e-316 XK27_06930 - - V ko:K01421 - ko00000 domain protein
NEKGAFBM_00587 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEKGAFBM_00588 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
NEKGAFBM_00589 5.45e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NEKGAFBM_00590 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEKGAFBM_00591 1.45e-191 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEKGAFBM_00592 3.93e-222 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKGAFBM_00593 1.24e-259 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
NEKGAFBM_00594 2.52e-108 - - - T - - - Belongs to the universal stress protein A family
NEKGAFBM_00595 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NEKGAFBM_00596 5.24e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEKGAFBM_00597 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NEKGAFBM_00598 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NEKGAFBM_00599 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NEKGAFBM_00600 2.95e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NEKGAFBM_00601 3.03e-122 mraW1 - - J - - - Putative rRNA methylase
NEKGAFBM_00602 9.32e-40 - - - - - - - -
NEKGAFBM_00603 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEKGAFBM_00604 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEKGAFBM_00605 5.9e-255 - - - S - - - Pfam Methyltransferase
NEKGAFBM_00606 5.81e-24 - - - N - - - Cell shape-determining protein MreB
NEKGAFBM_00610 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NEKGAFBM_00611 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
NEKGAFBM_00614 4.58e-230 - - - L - - - Belongs to the 'phage' integrase family
NEKGAFBM_00616 1.08e-104 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
NEKGAFBM_00617 1.6e-55 - - - - - - - -
NEKGAFBM_00618 1.15e-05 - - - - - - - -
NEKGAFBM_00621 2.71e-38 - - - - - - - -
NEKGAFBM_00622 1.08e-172 - - - L - - - Primase C terminal 1 (PriCT-1)
NEKGAFBM_00623 0.0 - - - S - - - Virulence-associated protein E
NEKGAFBM_00624 1.85e-82 - - - - - - - -
NEKGAFBM_00625 1.25e-93 - - - - - - - -
NEKGAFBM_00627 1.57e-62 - - - - - - - -
NEKGAFBM_00628 1.96e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NEKGAFBM_00629 0.0 ybeC - - E - - - amino acid
NEKGAFBM_00630 2.01e-132 - - - L - - - Transposase and inactivated derivatives, IS30 family
NEKGAFBM_00631 8.34e-60 - - - L ko:K07482 - ko00000 Integrase core domain
NEKGAFBM_00634 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
NEKGAFBM_00635 1.38e-71 - - - S - - - Cupin domain
NEKGAFBM_00636 1.31e-213 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
NEKGAFBM_00637 1.2e-242 ysdE - - P - - - Citrate transporter
NEKGAFBM_00638 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NEKGAFBM_00639 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEKGAFBM_00640 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEKGAFBM_00641 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NEKGAFBM_00642 3.99e-177 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NEKGAFBM_00643 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEKGAFBM_00644 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NEKGAFBM_00645 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NEKGAFBM_00646 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
NEKGAFBM_00647 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NEKGAFBM_00648 6.25e-106 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NEKGAFBM_00649 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NEKGAFBM_00650 1.19e-201 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEKGAFBM_00652 1e-200 - - - G - - - Peptidase_C39 like family
NEKGAFBM_00653 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEKGAFBM_00654 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NEKGAFBM_00655 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NEKGAFBM_00656 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
NEKGAFBM_00657 0.0 levR - - K - - - Sigma-54 interaction domain
NEKGAFBM_00658 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NEKGAFBM_00659 1.83e-112 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEKGAFBM_00660 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEKGAFBM_00661 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
NEKGAFBM_00662 4.82e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
NEKGAFBM_00663 6.33e-185 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEKGAFBM_00664 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
NEKGAFBM_00665 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEKGAFBM_00666 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NEKGAFBM_00667 6.04e-227 - - - EG - - - EamA-like transporter family
NEKGAFBM_00668 1.11e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEKGAFBM_00669 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
NEKGAFBM_00670 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NEKGAFBM_00671 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NEKGAFBM_00672 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NEKGAFBM_00673 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NEKGAFBM_00674 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEKGAFBM_00675 4.91e-265 yacL - - S - - - domain protein
NEKGAFBM_00676 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEKGAFBM_00677 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEKGAFBM_00678 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NEKGAFBM_00679 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEKGAFBM_00680 1.75e-126 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
NEKGAFBM_00681 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
NEKGAFBM_00682 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NEKGAFBM_00683 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEKGAFBM_00684 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NEKGAFBM_00685 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEKGAFBM_00686 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEKGAFBM_00687 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEKGAFBM_00688 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEKGAFBM_00689 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEKGAFBM_00690 2.59e-276 - - - L - - - Belongs to the 'phage' integrase family
NEKGAFBM_00697 1.76e-52 - - - S - - - protein disulfide oxidoreductase activity
NEKGAFBM_00703 3.66e-127 - - - - - - - -
NEKGAFBM_00708 2.8e-70 - - - S - - - Bacteriophage Mu Gam like protein
NEKGAFBM_00709 3.65e-79 - - - - - - - -
NEKGAFBM_00710 1.15e-65 - - - L - - - DnaD domain protein
NEKGAFBM_00711 4.5e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
NEKGAFBM_00712 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NEKGAFBM_00713 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEKGAFBM_00714 9.36e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NEKGAFBM_00715 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
NEKGAFBM_00716 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NEKGAFBM_00717 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NEKGAFBM_00718 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NEKGAFBM_00719 5.41e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NEKGAFBM_00720 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NEKGAFBM_00721 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NEKGAFBM_00722 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_00723 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NEKGAFBM_00724 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NEKGAFBM_00725 8.72e-297 ymfF - - S - - - Peptidase M16 inactive domain protein
NEKGAFBM_00726 0.0 ymfH - - S - - - Peptidase M16
NEKGAFBM_00727 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NEKGAFBM_00728 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEKGAFBM_00729 2.21e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NEKGAFBM_00730 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEKGAFBM_00731 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NEKGAFBM_00732 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
NEKGAFBM_00733 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NEKGAFBM_00734 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NEKGAFBM_00735 1.35e-93 - - - - - - - -
NEKGAFBM_00736 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NEKGAFBM_00737 2.07e-118 - - - - - - - -
NEKGAFBM_00738 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEKGAFBM_00739 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEKGAFBM_00740 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NEKGAFBM_00741 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEKGAFBM_00742 1.03e-60 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NEKGAFBM_00743 8.31e-275 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEKGAFBM_00744 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NEKGAFBM_00745 1.86e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NEKGAFBM_00746 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEKGAFBM_00747 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
NEKGAFBM_00748 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEKGAFBM_00749 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
NEKGAFBM_00750 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NEKGAFBM_00751 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NEKGAFBM_00752 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NEKGAFBM_00753 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
NEKGAFBM_00754 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NEKGAFBM_00755 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEKGAFBM_00756 4.53e-122 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NEKGAFBM_00757 7.94e-114 ykuL - - S - - - (CBS) domain
NEKGAFBM_00758 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NEKGAFBM_00759 7.85e-288 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NEKGAFBM_00760 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NEKGAFBM_00761 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NEKGAFBM_00762 1.6e-96 - - - - - - - -
NEKGAFBM_00763 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
NEKGAFBM_00764 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NEKGAFBM_00765 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NEKGAFBM_00766 7.88e-211 - - - G - - - Xylose isomerase domain protein TIM barrel
NEKGAFBM_00767 2.44e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
NEKGAFBM_00768 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
NEKGAFBM_00769 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEKGAFBM_00770 1.27e-224 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NEKGAFBM_00771 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NEKGAFBM_00772 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
NEKGAFBM_00773 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
NEKGAFBM_00774 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
NEKGAFBM_00775 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
NEKGAFBM_00777 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NEKGAFBM_00778 1.91e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEKGAFBM_00779 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NEKGAFBM_00780 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
NEKGAFBM_00781 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NEKGAFBM_00782 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
NEKGAFBM_00783 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NEKGAFBM_00784 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
NEKGAFBM_00785 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
NEKGAFBM_00786 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEKGAFBM_00787 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
NEKGAFBM_00788 1.11e-84 - - - - - - - -
NEKGAFBM_00789 6.21e-39 - - - - - - - -
NEKGAFBM_00790 2.43e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NEKGAFBM_00791 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEKGAFBM_00792 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
NEKGAFBM_00793 6.45e-111 - - - - - - - -
NEKGAFBM_00794 2.29e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEKGAFBM_00795 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NEKGAFBM_00796 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NEKGAFBM_00797 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEKGAFBM_00798 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NEKGAFBM_00799 1.24e-208 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
NEKGAFBM_00800 6.24e-61 yktA - - S - - - Belongs to the UPF0223 family
NEKGAFBM_00801 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NEKGAFBM_00802 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NEKGAFBM_00803 6.34e-257 - - - - - - - -
NEKGAFBM_00804 9.51e-135 - - - - - - - -
NEKGAFBM_00805 0.0 icaA - - M - - - Glycosyl transferase family group 2
NEKGAFBM_00806 0.0 - - - - - - - -
NEKGAFBM_00807 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NEKGAFBM_00808 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NEKGAFBM_00809 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NEKGAFBM_00810 6.06e-132 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NEKGAFBM_00811 2.56e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEKGAFBM_00812 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NEKGAFBM_00813 3.85e-157 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NEKGAFBM_00814 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NEKGAFBM_00815 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NEKGAFBM_00816 2.07e-240 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NEKGAFBM_00817 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NEKGAFBM_00818 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEKGAFBM_00819 7.41e-260 - - - EGP - - - Major Facilitator Superfamily
NEKGAFBM_00820 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEKGAFBM_00821 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEKGAFBM_00822 5.89e-204 - - - S - - - Tetratricopeptide repeat
NEKGAFBM_00823 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEKGAFBM_00824 6.48e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEKGAFBM_00825 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEKGAFBM_00826 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NEKGAFBM_00827 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
NEKGAFBM_00828 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
NEKGAFBM_00829 5.12e-31 - - - - - - - -
NEKGAFBM_00830 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NEKGAFBM_00831 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_00832 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEKGAFBM_00833 8.45e-162 epsB - - M - - - biosynthesis protein
NEKGAFBM_00834 4.97e-157 ywqD - - D - - - Capsular exopolysaccharide family
NEKGAFBM_00835 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NEKGAFBM_00836 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NEKGAFBM_00837 5.49e-163 tuaA - - M - - - Bacterial sugar transferase
NEKGAFBM_00838 1.4e-259 cps4F - - M - - - Glycosyl transferases group 1
NEKGAFBM_00839 3.84e-235 cps4G - - M - - - Glycosyltransferase Family 4
NEKGAFBM_00840 1.01e-292 - - - - - - - -
NEKGAFBM_00841 2.39e-228 cps4I - - M - - - Glycosyltransferase like family 2
NEKGAFBM_00842 0.0 cps4J - - S - - - MatE
NEKGAFBM_00843 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
NEKGAFBM_00844 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NEKGAFBM_00845 1.73e-217 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NEKGAFBM_00846 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NEKGAFBM_00847 3.13e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEKGAFBM_00848 6.62e-62 - - - - - - - -
NEKGAFBM_00849 3.4e-227 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NEKGAFBM_00850 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NEKGAFBM_00851 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
NEKGAFBM_00852 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NEKGAFBM_00853 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEKGAFBM_00854 7.9e-136 - - - K - - - Helix-turn-helix domain
NEKGAFBM_00855 2.87e-270 - - - EGP - - - Major facilitator Superfamily
NEKGAFBM_00856 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
NEKGAFBM_00857 1.14e-180 - - - Q - - - Methyltransferase
NEKGAFBM_00858 1.75e-43 - - - - - - - -
NEKGAFBM_00861 8.56e-74 - - - S - - - Phage integrase family
NEKGAFBM_00862 1.74e-20 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Transposase and inactivated derivatives
NEKGAFBM_00863 2.14e-53 - - - L - - - HTH-like domain
NEKGAFBM_00864 5.48e-05 - - - S - - - Short C-terminal domain
NEKGAFBM_00865 4.86e-19 - - - S - - - Short C-terminal domain
NEKGAFBM_00866 6.26e-75 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
NEKGAFBM_00867 0.0 - - - M - - - domain protein
NEKGAFBM_00868 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEKGAFBM_00869 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
NEKGAFBM_00870 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEKGAFBM_00871 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NEKGAFBM_00872 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_00873 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEKGAFBM_00874 1.17e-101 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
NEKGAFBM_00875 2.82e-206 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEKGAFBM_00876 4.27e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NEKGAFBM_00877 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEKGAFBM_00878 2.16e-103 - - - - - - - -
NEKGAFBM_00879 8.37e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
NEKGAFBM_00880 1.61e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NEKGAFBM_00881 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NEKGAFBM_00882 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NEKGAFBM_00883 0.0 sufI - - Q - - - Multicopper oxidase
NEKGAFBM_00884 1.19e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NEKGAFBM_00885 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
NEKGAFBM_00886 8.95e-60 - - - - - - - -
NEKGAFBM_00887 3.66e-226 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NEKGAFBM_00888 3.5e-307 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NEKGAFBM_00889 0.0 - - - P - - - Major Facilitator Superfamily
NEKGAFBM_00890 1.18e-121 - - - K - - - Transcriptional regulator PadR-like family
NEKGAFBM_00891 2.76e-59 - - - - - - - -
NEKGAFBM_00892 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NEKGAFBM_00893 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NEKGAFBM_00894 1.1e-280 - - - - - - - -
NEKGAFBM_00895 2.25e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEKGAFBM_00896 5.67e-187 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEKGAFBM_00897 5.18e-115 metP_2 - - U ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKGAFBM_00898 7.98e-158 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEKGAFBM_00899 1.06e-143 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
NEKGAFBM_00900 2.03e-225 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEKGAFBM_00901 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NEKGAFBM_00902 6.4e-54 - - - - - - - -
NEKGAFBM_00903 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEKGAFBM_00904 3.48e-40 - - - - - - - -
NEKGAFBM_00905 4.09e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
NEKGAFBM_00906 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
NEKGAFBM_00908 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NEKGAFBM_00909 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
NEKGAFBM_00910 1.08e-243 - - - - - - - -
NEKGAFBM_00911 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKGAFBM_00912 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NEKGAFBM_00913 2.06e-30 - - - - - - - -
NEKGAFBM_00914 2.14e-117 - - - K - - - acetyltransferase
NEKGAFBM_00915 1.88e-111 - - - K - - - GNAT family
NEKGAFBM_00916 8.08e-110 - - - S - - - ASCH
NEKGAFBM_00917 4.3e-124 - - - K - - - Cupin domain
NEKGAFBM_00918 5.09e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NEKGAFBM_00919 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEKGAFBM_00920 9.24e-180 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEKGAFBM_00921 5.3e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKGAFBM_00922 8.05e-33 - - - U - - - Preprotein translocase subunit SecB
NEKGAFBM_00923 1.04e-35 - - - - - - - -
NEKGAFBM_00925 6.01e-51 - - - - - - - -
NEKGAFBM_00926 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NEKGAFBM_00927 1.24e-99 - - - K - - - Transcriptional regulator
NEKGAFBM_00928 2.55e-100 - - - S ko:K02348 - ko00000 GNAT family
NEKGAFBM_00929 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEKGAFBM_00930 2.03e-75 - - - - - - - -
NEKGAFBM_00931 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
NEKGAFBM_00932 6.88e-170 - - - - - - - -
NEKGAFBM_00933 1.44e-225 - - - - - - - -
NEKGAFBM_00934 1.71e-87 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
NEKGAFBM_00935 1.43e-82 - - - M - - - LysM domain protein
NEKGAFBM_00936 7.98e-80 - - - M - - - Lysin motif
NEKGAFBM_00937 2.52e-08 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_00938 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEKGAFBM_00939 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEKGAFBM_00940 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEKGAFBM_00941 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEKGAFBM_00942 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEKGAFBM_00943 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
NEKGAFBM_00944 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
NEKGAFBM_00945 3.89e-208 lysR5 - - K - - - LysR substrate binding domain
NEKGAFBM_00946 1.49e-252 - - - M - - - MucBP domain
NEKGAFBM_00947 0.0 - - - - - - - -
NEKGAFBM_00948 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NEKGAFBM_00949 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NEKGAFBM_00950 3.36e-216 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NEKGAFBM_00951 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NEKGAFBM_00952 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
NEKGAFBM_00953 2.46e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
NEKGAFBM_00954 1.13e-257 yueF - - S - - - AI-2E family transporter
NEKGAFBM_00955 7.3e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NEKGAFBM_00956 1.67e-166 pbpX - - V - - - Beta-lactamase
NEKGAFBM_00957 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
NEKGAFBM_00958 8.01e-64 - - - K - - - sequence-specific DNA binding
NEKGAFBM_00959 4.78e-171 lytE - - M - - - NlpC/P60 family
NEKGAFBM_00960 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NEKGAFBM_00961 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NEKGAFBM_00962 1.9e-168 - - - - - - - -
NEKGAFBM_00963 4.14e-132 - - - K - - - DNA-templated transcription, initiation
NEKGAFBM_00964 1.64e-35 - - - - - - - -
NEKGAFBM_00965 1.95e-41 - - - - - - - -
NEKGAFBM_00966 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
NEKGAFBM_00967 1.06e-68 - - - - - - - -
NEKGAFBM_00968 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
NEKGAFBM_00969 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NEKGAFBM_00970 5.36e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEKGAFBM_00971 0.0 - - - M - - - domain protein
NEKGAFBM_00972 6.86e-175 - - - K - - - helix_turn_helix, arabinose operon control protein
NEKGAFBM_00973 3.43e-189 cps3J - - M - - - Domain of unknown function (DUF4422)
NEKGAFBM_00974 5.67e-257 cps3I - - G - - - Acyltransferase family
NEKGAFBM_00975 3.9e-251 cps3H - - - - - - -
NEKGAFBM_00976 3.48e-208 cps3F - - - - - - -
NEKGAFBM_00977 1.69e-144 cps3E - - - - - - -
NEKGAFBM_00978 3.93e-260 cps3D - - - - - - -
NEKGAFBM_00979 6.91e-283 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NEKGAFBM_00980 3.28e-229 cps3B - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NEKGAFBM_00981 9.99e-216 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NEKGAFBM_00982 1.17e-156 CP_1020 - - S - - - zinc ion binding
NEKGAFBM_00984 5.05e-70 - - - S - - - SMI1-KNR4 cell-wall
NEKGAFBM_00986 2.91e-32 - - - S - - - Barstar (barnase inhibitor)
NEKGAFBM_00989 4.33e-61 - - - - - - - -
NEKGAFBM_00990 7.76e-17 - - - - - - - -
NEKGAFBM_00992 1.44e-104 - - - - - - - -
NEKGAFBM_01014 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NEKGAFBM_01015 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
NEKGAFBM_01016 5.37e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NEKGAFBM_01017 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NEKGAFBM_01018 7.52e-263 coiA - - S ko:K06198 - ko00000 Competence protein
NEKGAFBM_01019 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NEKGAFBM_01020 2.24e-148 yjbH - - Q - - - Thioredoxin
NEKGAFBM_01021 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NEKGAFBM_01022 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEKGAFBM_01023 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEKGAFBM_01024 2.51e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NEKGAFBM_01025 1.6e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NEKGAFBM_01026 1.55e-74 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NEKGAFBM_01027 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
NEKGAFBM_01028 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEKGAFBM_01029 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NEKGAFBM_01031 8.82e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NEKGAFBM_01032 3.55e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NEKGAFBM_01033 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEKGAFBM_01034 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NEKGAFBM_01035 4.99e-224 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NEKGAFBM_01036 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
NEKGAFBM_01037 1.35e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NEKGAFBM_01038 2.58e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEKGAFBM_01039 7.01e-76 ftsL - - D - - - Cell division protein FtsL
NEKGAFBM_01040 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NEKGAFBM_01041 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEKGAFBM_01042 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEKGAFBM_01043 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEKGAFBM_01044 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NEKGAFBM_01045 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NEKGAFBM_01046 1.1e-293 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEKGAFBM_01047 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEKGAFBM_01048 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
NEKGAFBM_01049 2.06e-187 ylmH - - S - - - S4 domain protein
NEKGAFBM_01050 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NEKGAFBM_01051 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEKGAFBM_01052 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NEKGAFBM_01053 3.51e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NEKGAFBM_01054 7.74e-47 - - - - - - - -
NEKGAFBM_01055 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEKGAFBM_01056 3.03e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NEKGAFBM_01057 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
NEKGAFBM_01058 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEKGAFBM_01059 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
NEKGAFBM_01060 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
NEKGAFBM_01061 5.92e-153 - - - N - - - WxL domain surface cell wall-binding
NEKGAFBM_01062 7.05e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
NEKGAFBM_01063 0.0 - - - N - - - domain, Protein
NEKGAFBM_01064 1.98e-156 pgm6 - - G - - - phosphoglycerate mutase
NEKGAFBM_01065 1.02e-155 - - - S - - - repeat protein
NEKGAFBM_01066 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NEKGAFBM_01067 1.6e-221 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEKGAFBM_01069 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEKGAFBM_01070 1.45e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEKGAFBM_01071 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEKGAFBM_01072 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEKGAFBM_01073 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NEKGAFBM_01074 2.49e-73 - - - S - - - Enterocin A Immunity
NEKGAFBM_01075 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NEKGAFBM_01076 5.81e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NEKGAFBM_01077 4.68e-235 - - - D ko:K06889 - ko00000 Alpha beta
NEKGAFBM_01078 1.04e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
NEKGAFBM_01079 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
NEKGAFBM_01080 4.3e-58 - - - L - - - Belongs to the 'phage' integrase family
NEKGAFBM_01085 3.53e-32 - - - - - - - -
NEKGAFBM_01087 2.89e-78 dinG 2.7.7.7, 3.6.4.12 - L ko:K02342,ko:K03722,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA-directed DNA polymerase activity
NEKGAFBM_01088 4.38e-48 - - - S - - - Pfam:Peptidase_M78
NEKGAFBM_01089 3.49e-30 - - - K - - - Helix-turn-helix XRE-family like proteins
NEKGAFBM_01091 1.38e-119 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
NEKGAFBM_01093 1.29e-34 - - - S - - - Domain of unknown function (DUF1883)
NEKGAFBM_01104 1.32e-97 - - - L - - - DnaD domain protein
NEKGAFBM_01105 1.03e-208 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NEKGAFBM_01107 3.4e-61 - - - - - - - -
NEKGAFBM_01108 2.59e-26 - - - - - - - -
NEKGAFBM_01110 1.02e-14 - - - S - - - YopX protein
NEKGAFBM_01115 1.82e-31 - - - - - - - -
NEKGAFBM_01117 4.46e-27 - - - - - - - -
NEKGAFBM_01118 3.68e-45 - - - S - - - Transcriptional regulator, RinA family
NEKGAFBM_01122 3.48e-79 - - - V - - - HNH nucleases
NEKGAFBM_01123 1.44e-50 - - - L - - - Phage terminase, small subunit
NEKGAFBM_01124 0.0 terL - - S - - - overlaps another CDS with the same product name
NEKGAFBM_01126 1.72e-180 - - - S - - - Phage portal protein
NEKGAFBM_01127 2.46e-102 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
NEKGAFBM_01128 3.31e-148 - - - S - - - Phage capsid family
NEKGAFBM_01129 4.11e-31 - - - S - - - Phage gp6-like head-tail connector protein
NEKGAFBM_01130 3.13e-17 - - - S - - - Phage head-tail joining protein
NEKGAFBM_01131 4.57e-37 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NEKGAFBM_01132 8.79e-31 - - - S - - - Protein of unknown function (DUF806)
NEKGAFBM_01133 3.43e-95 - - - S - - - Phage tail tube protein
NEKGAFBM_01134 1.5e-18 - - - S - - - Phage tail assembly chaperone proteins, TAC
NEKGAFBM_01136 1.83e-257 - - - L - - - Phage tail tape measure protein TP901
NEKGAFBM_01137 1.55e-281 - - - S - - - Phage tail protein
NEKGAFBM_01138 0.0 - - - S - - - Phage minor structural protein
NEKGAFBM_01139 4.52e-122 - - - - - - - -
NEKGAFBM_01142 2.58e-73 - - - - - - - -
NEKGAFBM_01143 7.28e-220 - - - M - - - Glycosyl hydrolases family 25
NEKGAFBM_01144 3.19e-50 - - - S - - - Haemolysin XhlA
NEKGAFBM_01146 3.93e-99 - - - T - - - Universal stress protein family
NEKGAFBM_01147 5.73e-316 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_01148 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEKGAFBM_01150 7.62e-97 - - - - - - - -
NEKGAFBM_01151 2.9e-139 - - - - - - - -
NEKGAFBM_01152 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NEKGAFBM_01153 1.15e-281 pbpX - - V - - - Beta-lactamase
NEKGAFBM_01154 4.75e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NEKGAFBM_01155 1.01e-199 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NEKGAFBM_01156 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEKGAFBM_01157 1.43e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NEKGAFBM_01161 3.58e-126 cps3J - - M - - - Domain of unknown function (DUF4422)
NEKGAFBM_01162 3.06e-58 - - - M - - - group 2 family protein
NEKGAFBM_01163 7.34e-128 cps2G - - M - - - Stealth protein CR2, conserved region 2
NEKGAFBM_01164 6.15e-112 - - - M - - - transferase activity, transferring glycosyl groups
NEKGAFBM_01165 8.59e-47 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
NEKGAFBM_01166 8.35e-217 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NEKGAFBM_01167 4.12e-115 - - - M - - - Parallel beta-helix repeats
NEKGAFBM_01168 2.29e-201 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEKGAFBM_01169 9.23e-130 - - - L - - - Integrase
NEKGAFBM_01170 2.36e-170 epsB - - M - - - biosynthesis protein
NEKGAFBM_01171 8.62e-166 ywqD - - D - - - Capsular exopolysaccharide family
NEKGAFBM_01172 1.62e-182 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NEKGAFBM_01173 5.41e-226 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NEKGAFBM_01174 1.39e-158 tuaA - - M - - - Bacterial sugar transferase
NEKGAFBM_01175 1.1e-255 cps4F - - M - - - Glycosyl transferases group 1
NEKGAFBM_01176 6.22e-243 cps4G - - M - - - Glycosyltransferase Family 4
NEKGAFBM_01177 1.32e-214 - - - - - - - -
NEKGAFBM_01178 4.86e-152 cps4I - - M - - - Glycosyltransferase like family 2
NEKGAFBM_01179 1.37e-50 - - - M - - - PFAM Glycosyl transferase family 2
NEKGAFBM_01180 1.47e-97 cps2J - - S - - - Polysaccharide biosynthesis protein
NEKGAFBM_01181 2.91e-23 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
NEKGAFBM_01183 2.94e-61 - - - S - - - Tetratricopeptide repeat
NEKGAFBM_01184 3.21e-109 - - - L - - - AAA ATPase domain
NEKGAFBM_01185 5.77e-111 - 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 UvrD/REP helicase N-terminal domain
NEKGAFBM_01186 2.26e-16 - - - - - - - -
NEKGAFBM_01187 2.91e-74 - - - L - - - Belongs to the 'phage' integrase family
NEKGAFBM_01191 1.83e-26 - - - M - - - domain protein
NEKGAFBM_01192 8.71e-33 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
NEKGAFBM_01195 2.61e-205 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEKGAFBM_01196 1.06e-138 - - - L - - - Resolvase, N terminal domain
NEKGAFBM_01197 2.47e-144 - - - L ko:K07497 - ko00000 hmm pf00665
NEKGAFBM_01198 3.29e-232 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
NEKGAFBM_01199 1.95e-220 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
NEKGAFBM_01200 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEKGAFBM_01201 7.07e-106 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NEKGAFBM_01202 1.98e-06 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
NEKGAFBM_01203 4.28e-81 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEKGAFBM_01204 5.82e-124 tnpR1 - - L - - - Resolvase, N terminal domain
NEKGAFBM_01205 1.49e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEKGAFBM_01206 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NEKGAFBM_01207 2.01e-128 tnpR - - L - - - Resolvase, N terminal domain
NEKGAFBM_01208 2.42e-61 - - - S - - - FRG
NEKGAFBM_01209 6.72e-316 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
NEKGAFBM_01210 1.49e-48 - - - - - - - -
NEKGAFBM_01211 1.3e-255 - - - S - - - Domain of unknown function (DUF1998)
NEKGAFBM_01212 0.0 - - - KL - - - Helicase conserved C-terminal domain
NEKGAFBM_01214 7.08e-236 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
NEKGAFBM_01215 1.77e-12 - - - - - - - -
NEKGAFBM_01216 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NEKGAFBM_01217 0.0 traA - - L - - - MobA MobL family protein
NEKGAFBM_01218 1.69e-37 - - - - - - - -
NEKGAFBM_01219 1.47e-55 - - - - - - - -
NEKGAFBM_01220 4.49e-74 - - - L - - - Transposase DDE domain
NEKGAFBM_01221 5.98e-212 - - - P - - - CorA-like Mg2+ transporter protein
NEKGAFBM_01222 6.99e-109 - - - - - - - -
NEKGAFBM_01223 2.83e-58 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
NEKGAFBM_01225 6.13e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
NEKGAFBM_01227 2.66e-159 - - - L - - - Transposase and inactivated derivatives, IS30 family
NEKGAFBM_01228 5.73e-240 - - - L - - - PFAM Integrase catalytic region
NEKGAFBM_01229 9.17e-126 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NEKGAFBM_01230 1.14e-143 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NEKGAFBM_01231 5.99e-234 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NEKGAFBM_01232 1.71e-240 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
NEKGAFBM_01233 4.73e-53 - - - M - - - LysM domain protein
NEKGAFBM_01234 5.83e-182 - - - L - - - COG3547 Transposase and inactivated derivatives
NEKGAFBM_01235 0.0 eriC - - P ko:K03281 - ko00000 chloride
NEKGAFBM_01236 7.81e-247 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEKGAFBM_01239 6.26e-108 - - - L - - - C-5 cytosine-specific DNA methylase
NEKGAFBM_01240 8.9e-106 - - - S - - - Phage transcriptional regulator, ArpU family
NEKGAFBM_01244 3.18e-61 - - - L - - - transposase activity
NEKGAFBM_01245 7.33e-237 - - - S - - - Phage terminase, large subunit, PBSX family
NEKGAFBM_01246 2.67e-137 - - - S - - - Phage portal protein, SPP1 Gp6-like
NEKGAFBM_01247 9.74e-42 - - - S - - - Phage minor capsid protein 2
NEKGAFBM_01248 4.43e-10 - - - S - - - Phage minor capsid protein 2
NEKGAFBM_01250 6.05e-136 - - - - - - - -
NEKGAFBM_01251 4.22e-06 - - - - - - - -
NEKGAFBM_01252 2.68e-20 - - - - - - - -
NEKGAFBM_01256 7.77e-60 - - - N - - - domain, Protein
NEKGAFBM_01259 8.39e-166 - - - L - - - Phage tail tape measure protein TP901
NEKGAFBM_01261 8.7e-125 - - - S - - - Prophage endopeptidase tail
NEKGAFBM_01264 0.0 - - - S - - - Calcineurin-like phosphoesterase
NEKGAFBM_01267 7.45e-77 - - - - - - - -
NEKGAFBM_01268 9.75e-33 - - - - - - - -
NEKGAFBM_01269 2.54e-238 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEKGAFBM_01270 3.61e-61 - - - - - - - -
NEKGAFBM_01271 1.53e-51 - - - S - - - Bacteriophage holin
NEKGAFBM_01277 5.22e-229 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NEKGAFBM_01278 1.5e-82 - - - L - - - nuclease
NEKGAFBM_01279 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEKGAFBM_01280 5.82e-141 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NEKGAFBM_01281 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEKGAFBM_01282 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEKGAFBM_01283 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NEKGAFBM_01284 2.24e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NEKGAFBM_01285 1.26e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEKGAFBM_01286 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEKGAFBM_01287 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NEKGAFBM_01288 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEKGAFBM_01289 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
NEKGAFBM_01290 2.22e-153 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEKGAFBM_01291 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
NEKGAFBM_01292 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NEKGAFBM_01293 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
NEKGAFBM_01294 1.53e-212 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEKGAFBM_01295 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NEKGAFBM_01296 2.86e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NEKGAFBM_01297 9.25e-271 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
NEKGAFBM_01298 2.8e-187 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
NEKGAFBM_01299 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEKGAFBM_01300 9.25e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
NEKGAFBM_01301 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NEKGAFBM_01302 9.91e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
NEKGAFBM_01303 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NEKGAFBM_01304 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
NEKGAFBM_01305 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NEKGAFBM_01306 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEKGAFBM_01307 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NEKGAFBM_01308 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NEKGAFBM_01309 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_01310 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEKGAFBM_01311 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEKGAFBM_01312 0.0 ydaO - - E - - - amino acid
NEKGAFBM_01313 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NEKGAFBM_01314 7.67e-198 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NEKGAFBM_01315 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NEKGAFBM_01316 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NEKGAFBM_01317 3.43e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NEKGAFBM_01318 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEKGAFBM_01319 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEKGAFBM_01320 1.69e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEKGAFBM_01321 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
NEKGAFBM_01322 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NEKGAFBM_01323 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEKGAFBM_01324 1.39e-200 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NEKGAFBM_01325 4.48e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NEKGAFBM_01326 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NEKGAFBM_01327 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEKGAFBM_01328 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEKGAFBM_01329 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NEKGAFBM_01330 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
NEKGAFBM_01331 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NEKGAFBM_01332 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NEKGAFBM_01333 1.04e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEKGAFBM_01334 2.82e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NEKGAFBM_01335 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NEKGAFBM_01336 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
NEKGAFBM_01337 0.0 nox - - C - - - NADH oxidase
NEKGAFBM_01338 2.6e-206 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NEKGAFBM_01339 4.95e-310 - - - - - - - -
NEKGAFBM_01340 6.83e-256 - - - S - - - Protein conserved in bacteria
NEKGAFBM_01341 2.74e-277 ydaM - - M - - - Glycosyl transferase family group 2
NEKGAFBM_01342 0.0 - - - S - - - Bacterial cellulose synthase subunit
NEKGAFBM_01343 7.91e-172 - - - T - - - diguanylate cyclase activity
NEKGAFBM_01344 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEKGAFBM_01345 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
NEKGAFBM_01346 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
NEKGAFBM_01347 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NEKGAFBM_01348 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
NEKGAFBM_01349 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEKGAFBM_01350 4.63e-135 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NEKGAFBM_01351 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
NEKGAFBM_01352 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
NEKGAFBM_01353 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEKGAFBM_01354 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEKGAFBM_01355 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEKGAFBM_01356 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEKGAFBM_01357 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NEKGAFBM_01358 6.07e-114 - - - S - - - Short repeat of unknown function (DUF308)
NEKGAFBM_01359 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NEKGAFBM_01360 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NEKGAFBM_01361 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NEKGAFBM_01362 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEKGAFBM_01363 8.95e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEKGAFBM_01364 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEKGAFBM_01366 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
NEKGAFBM_01367 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NEKGAFBM_01368 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEKGAFBM_01369 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NEKGAFBM_01370 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEKGAFBM_01371 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEKGAFBM_01372 5.11e-171 - - - - - - - -
NEKGAFBM_01373 0.0 eriC - - P ko:K03281 - ko00000 chloride
NEKGAFBM_01374 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NEKGAFBM_01375 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
NEKGAFBM_01376 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NEKGAFBM_01377 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NEKGAFBM_01378 0.0 - - - M - - - Domain of unknown function (DUF5011)
NEKGAFBM_01379 0.0 - - - M - - - Domain of unknown function (DUF5011)
NEKGAFBM_01380 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKGAFBM_01381 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_01382 7.98e-137 - - - - - - - -
NEKGAFBM_01383 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEKGAFBM_01384 5.71e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEKGAFBM_01385 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NEKGAFBM_01386 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NEKGAFBM_01387 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
NEKGAFBM_01388 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NEKGAFBM_01389 1.46e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NEKGAFBM_01390 3.09e-213 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
NEKGAFBM_01391 5.13e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NEKGAFBM_01392 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
NEKGAFBM_01393 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEKGAFBM_01394 2.31e-155 - - - S - - - Protein of unknown function (DUF1361)
NEKGAFBM_01395 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEKGAFBM_01396 2.18e-182 ybbR - - S - - - YbbR-like protein
NEKGAFBM_01397 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEKGAFBM_01398 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEKGAFBM_01399 3.15e-158 - - - T - - - EAL domain
NEKGAFBM_01400 8.04e-190 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
NEKGAFBM_01401 7.01e-135 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_01402 1.46e-263 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NEKGAFBM_01403 3.38e-70 - - - - - - - -
NEKGAFBM_01404 2.05e-94 - - - - - - - -
NEKGAFBM_01405 7.06e-169 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NEKGAFBM_01406 7.34e-180 - - - EGP - - - Transmembrane secretion effector
NEKGAFBM_01407 3.19e-41 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NEKGAFBM_01408 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEKGAFBM_01409 5.03e-183 - - - - - - - -
NEKGAFBM_01411 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
NEKGAFBM_01412 3.88e-46 - - - - - - - -
NEKGAFBM_01413 2.08e-117 - - - V - - - VanZ like family
NEKGAFBM_01414 1.06e-314 - - - EGP - - - Major Facilitator
NEKGAFBM_01415 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NEKGAFBM_01416 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NEKGAFBM_01417 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NEKGAFBM_01418 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
NEKGAFBM_01419 6.16e-107 - - - K - - - Transcriptional regulator
NEKGAFBM_01420 1.36e-27 - - - - - - - -
NEKGAFBM_01421 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NEKGAFBM_01422 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEKGAFBM_01423 3.3e-199 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NEKGAFBM_01424 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEKGAFBM_01425 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NEKGAFBM_01426 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEKGAFBM_01427 0.0 oatA - - I - - - Acyltransferase
NEKGAFBM_01428 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NEKGAFBM_01429 1.89e-90 - - - O - - - OsmC-like protein
NEKGAFBM_01430 1.21e-63 - - - - - - - -
NEKGAFBM_01431 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
NEKGAFBM_01432 6.12e-115 - - - - - - - -
NEKGAFBM_01433 5.24e-191 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NEKGAFBM_01434 7.48e-96 - - - F - - - Nudix hydrolase
NEKGAFBM_01435 1.48e-27 - - - - - - - -
NEKGAFBM_01436 7.32e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
NEKGAFBM_01437 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NEKGAFBM_01438 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
NEKGAFBM_01439 1.01e-188 - - - - - - - -
NEKGAFBM_01440 4.02e-145 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
NEKGAFBM_01441 3.21e-268 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEKGAFBM_01442 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEKGAFBM_01443 1.23e-52 - - - - - - - -
NEKGAFBM_01445 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_01446 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NEKGAFBM_01447 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEKGAFBM_01448 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEKGAFBM_01449 2.02e-107 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEKGAFBM_01450 7.77e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEKGAFBM_01451 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEKGAFBM_01452 1.57e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
NEKGAFBM_01453 0.0 steT - - E ko:K03294 - ko00000 amino acid
NEKGAFBM_01454 3.1e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEKGAFBM_01455 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
NEKGAFBM_01456 3.08e-93 - - - K - - - MarR family
NEKGAFBM_01457 2.27e-269 - - - EGP - - - Major Facilitator Superfamily
NEKGAFBM_01458 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
NEKGAFBM_01459 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_01460 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEKGAFBM_01461 1.13e-102 rppH3 - - F - - - NUDIX domain
NEKGAFBM_01462 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
NEKGAFBM_01463 1.61e-36 - - - - - - - -
NEKGAFBM_01464 2.61e-163 pgm3 - - G - - - Phosphoglycerate mutase family
NEKGAFBM_01465 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
NEKGAFBM_01466 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NEKGAFBM_01467 1.39e-225 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NEKGAFBM_01468 1.06e-141 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NEKGAFBM_01469 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NEKGAFBM_01470 5.95e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
NEKGAFBM_01471 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NEKGAFBM_01472 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NEKGAFBM_01473 1.08e-71 - - - - - - - -
NEKGAFBM_01474 1.37e-83 - - - K - - - Helix-turn-helix domain
NEKGAFBM_01475 0.0 - - - L - - - AAA domain
NEKGAFBM_01476 2.01e-149 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_01477 1.85e-75 - - - K - - - HxlR-like helix-turn-helix
NEKGAFBM_01478 4.73e-302 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
NEKGAFBM_01479 7.04e-299 - - - S - - - Cysteine-rich secretory protein family
NEKGAFBM_01480 3.61e-61 - - - S - - - MORN repeat
NEKGAFBM_01481 0.0 XK27_09800 - - I - - - Acyltransferase family
NEKGAFBM_01482 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
NEKGAFBM_01483 1.95e-116 - - - - - - - -
NEKGAFBM_01484 5.74e-32 - - - - - - - -
NEKGAFBM_01485 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
NEKGAFBM_01486 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
NEKGAFBM_01487 1.59e-189 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
NEKGAFBM_01488 4.25e-211 yjdB - - S - - - Domain of unknown function (DUF4767)
NEKGAFBM_01489 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NEKGAFBM_01490 6.27e-131 - - - G - - - Glycogen debranching enzyme
NEKGAFBM_01491 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NEKGAFBM_01492 2.88e-48 - - - V - - - type I restriction modification DNA specificity domain
NEKGAFBM_01493 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NEKGAFBM_01494 5.79e-293 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 PFAM N-6 DNA methylase
NEKGAFBM_01495 1.11e-84 - - - V - - - Type I restriction modification DNA specificity domain
NEKGAFBM_01496 2.1e-218 - - - L - - - Belongs to the 'phage' integrase family
NEKGAFBM_01497 8.86e-28 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NEKGAFBM_01498 2.76e-110 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
NEKGAFBM_01499 0.0 - - - M - - - MucBP domain
NEKGAFBM_01500 1.42e-08 - - - - - - - -
NEKGAFBM_01501 2.87e-112 - - - S - - - AAA domain
NEKGAFBM_01502 7.15e-178 - - - K - - - sequence-specific DNA binding
NEKGAFBM_01503 1.88e-124 - - - K - - - Helix-turn-helix domain
NEKGAFBM_01504 1.32e-218 - - - K - - - Transcriptional regulator
NEKGAFBM_01505 0.0 - - - C - - - FMN_bind
NEKGAFBM_01507 4.3e-106 - - - K - - - Transcriptional regulator
NEKGAFBM_01508 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NEKGAFBM_01509 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NEKGAFBM_01510 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NEKGAFBM_01511 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEKGAFBM_01512 3.79e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NEKGAFBM_01513 5.44e-56 - - - - - - - -
NEKGAFBM_01514 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
NEKGAFBM_01515 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NEKGAFBM_01516 1.36e-208 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEKGAFBM_01517 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEKGAFBM_01518 2.91e-179 - - - S - - - NADPH-dependent FMN reductase
NEKGAFBM_01519 1.12e-243 - - - - - - - -
NEKGAFBM_01520 3.28e-278 yibE - - S - - - overlaps another CDS with the same product name
NEKGAFBM_01521 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
NEKGAFBM_01522 4.77e-130 - - - K - - - FR47-like protein
NEKGAFBM_01523 1.5e-156 gpm5 - - G - - - Phosphoglycerate mutase family
NEKGAFBM_01524 3.33e-64 - - - - - - - -
NEKGAFBM_01525 7.32e-247 - - - I - - - alpha/beta hydrolase fold
NEKGAFBM_01526 0.0 xylP2 - - G - - - symporter
NEKGAFBM_01527 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEKGAFBM_01528 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
NEKGAFBM_01529 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NEKGAFBM_01530 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NEKGAFBM_01531 9.88e-124 azlC - - E - - - branched-chain amino acid
NEKGAFBM_01532 1.65e-17 azlC - - E - - - branched-chain amino acid
NEKGAFBM_01533 1.75e-47 - - - K - - - MerR HTH family regulatory protein
NEKGAFBM_01534 1.46e-170 - - - - - - - -
NEKGAFBM_01535 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
NEKGAFBM_01536 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NEKGAFBM_01537 6.41e-111 - - - K - - - MerR HTH family regulatory protein
NEKGAFBM_01538 1.36e-77 - - - - - - - -
NEKGAFBM_01539 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
NEKGAFBM_01540 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NEKGAFBM_01541 4.6e-169 - - - S - - - Putative threonine/serine exporter
NEKGAFBM_01542 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
NEKGAFBM_01543 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEKGAFBM_01544 5.89e-153 - - - I - - - phosphatase
NEKGAFBM_01545 3.88e-198 - - - I - - - alpha/beta hydrolase fold
NEKGAFBM_01546 2.49e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEKGAFBM_01547 1.7e-118 - - - K - - - Transcriptional regulator
NEKGAFBM_01548 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NEKGAFBM_01549 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NEKGAFBM_01550 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NEKGAFBM_01551 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
NEKGAFBM_01552 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEKGAFBM_01560 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NEKGAFBM_01561 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEKGAFBM_01562 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_01563 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEKGAFBM_01564 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEKGAFBM_01565 4.08e-147 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
NEKGAFBM_01566 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEKGAFBM_01567 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEKGAFBM_01568 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEKGAFBM_01569 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NEKGAFBM_01570 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEKGAFBM_01571 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NEKGAFBM_01572 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEKGAFBM_01573 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEKGAFBM_01574 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEKGAFBM_01575 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEKGAFBM_01576 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEKGAFBM_01577 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEKGAFBM_01578 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NEKGAFBM_01579 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEKGAFBM_01580 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEKGAFBM_01581 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEKGAFBM_01582 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEKGAFBM_01583 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEKGAFBM_01584 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEKGAFBM_01585 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEKGAFBM_01586 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEKGAFBM_01587 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NEKGAFBM_01588 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NEKGAFBM_01589 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEKGAFBM_01590 5.28e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEKGAFBM_01591 9.87e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEKGAFBM_01592 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEKGAFBM_01593 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEKGAFBM_01594 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEKGAFBM_01595 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NEKGAFBM_01596 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEKGAFBM_01597 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
NEKGAFBM_01598 5.37e-112 - - - S - - - NusG domain II
NEKGAFBM_01599 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NEKGAFBM_01600 3.19e-194 - - - S - - - FMN_bind
NEKGAFBM_01601 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEKGAFBM_01602 3.42e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEKGAFBM_01603 3.47e-212 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEKGAFBM_01604 2.49e-186 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEKGAFBM_01605 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEKGAFBM_01606 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEKGAFBM_01607 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NEKGAFBM_01608 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
NEKGAFBM_01609 5.79e-234 - - - S - - - Membrane
NEKGAFBM_01610 7.65e-259 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
NEKGAFBM_01611 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NEKGAFBM_01612 6.73e-211 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEKGAFBM_01613 4.68e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
NEKGAFBM_01614 1.23e-251 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NEKGAFBM_01615 1.94e-279 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NEKGAFBM_01616 6.15e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
NEKGAFBM_01617 2.01e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
NEKGAFBM_01618 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
NEKGAFBM_01619 1.66e-53 - - - K - - - Helix-turn-helix domain
NEKGAFBM_01620 2.85e-164 - - - K - - - Helix-turn-helix domain
NEKGAFBM_01621 5.24e-195 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NEKGAFBM_01622 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEKGAFBM_01623 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NEKGAFBM_01624 5.19e-223 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEKGAFBM_01625 1.18e-66 - - - - - - - -
NEKGAFBM_01626 1.78e-212 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NEKGAFBM_01627 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NEKGAFBM_01628 8.69e-230 citR - - K - - - sugar-binding domain protein
NEKGAFBM_01629 1.92e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
NEKGAFBM_01630 1.07e-241 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NEKGAFBM_01631 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
NEKGAFBM_01632 3.32e-210 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
NEKGAFBM_01633 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
NEKGAFBM_01634 5.69e-185 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NEKGAFBM_01635 6.87e-33 - - - K - - - sequence-specific DNA binding
NEKGAFBM_01638 4.31e-313 yfmL - - L - - - DEAD DEAH box helicase
NEKGAFBM_01639 1.94e-245 mocA - - S - - - Oxidoreductase
NEKGAFBM_01640 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NEKGAFBM_01641 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
NEKGAFBM_01642 4.68e-187 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEKGAFBM_01643 5.63e-196 gntR - - K - - - rpiR family
NEKGAFBM_01644 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEKGAFBM_01645 7.06e-307 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_01646 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NEKGAFBM_01647 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_01648 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEKGAFBM_01649 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NEKGAFBM_01650 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEKGAFBM_01651 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEKGAFBM_01652 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEKGAFBM_01653 9.48e-263 camS - - S - - - sex pheromone
NEKGAFBM_01654 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEKGAFBM_01655 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NEKGAFBM_01656 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NEKGAFBM_01657 2.67e-119 yebE - - S - - - UPF0316 protein
NEKGAFBM_01658 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEKGAFBM_01659 1.69e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NEKGAFBM_01660 9.47e-236 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NEKGAFBM_01661 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NEKGAFBM_01662 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEKGAFBM_01663 6.96e-153 - - - S - - - L,D-transpeptidase catalytic domain
NEKGAFBM_01664 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NEKGAFBM_01665 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NEKGAFBM_01666 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NEKGAFBM_01667 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NEKGAFBM_01668 0.0 - - - S ko:K06889 - ko00000 Alpha beta
NEKGAFBM_01669 6.07e-33 - - - - - - - -
NEKGAFBM_01670 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
NEKGAFBM_01671 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NEKGAFBM_01672 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NEKGAFBM_01673 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NEKGAFBM_01674 6.5e-215 mleR - - K - - - LysR family
NEKGAFBM_01675 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
NEKGAFBM_01676 8.08e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NEKGAFBM_01677 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEKGAFBM_01678 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NEKGAFBM_01682 0.0 mdr - - EGP - - - Major Facilitator
NEKGAFBM_01683 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEKGAFBM_01684 3.21e-155 - - - - - - - -
NEKGAFBM_01685 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEKGAFBM_01686 7.89e-216 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
NEKGAFBM_01687 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NEKGAFBM_01688 2.53e-240 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NEKGAFBM_01689 1.33e-292 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NEKGAFBM_01691 2.07e-200 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NEKGAFBM_01692 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
NEKGAFBM_01693 1.25e-124 - - - - - - - -
NEKGAFBM_01694 5.46e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
NEKGAFBM_01695 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
NEKGAFBM_01707 4.54e-54 - - - - - - - -
NEKGAFBM_01709 4.41e-316 - - - EGP - - - Major Facilitator
NEKGAFBM_01710 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEKGAFBM_01711 4.26e-109 cvpA - - S - - - Colicin V production protein
NEKGAFBM_01712 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NEKGAFBM_01713 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NEKGAFBM_01714 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
NEKGAFBM_01715 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NEKGAFBM_01716 4.4e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
NEKGAFBM_01717 4.79e-272 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
NEKGAFBM_01718 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NEKGAFBM_01720 2.77e-30 - - - - - - - -
NEKGAFBM_01722 1.63e-133 - - - K - - - Helix-turn-helix XRE-family like proteins
NEKGAFBM_01723 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NEKGAFBM_01724 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NEKGAFBM_01725 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NEKGAFBM_01726 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NEKGAFBM_01727 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NEKGAFBM_01728 1.01e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NEKGAFBM_01729 1.54e-228 ydbI - - K - - - AI-2E family transporter
NEKGAFBM_01730 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEKGAFBM_01731 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NEKGAFBM_01733 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
NEKGAFBM_01734 1.88e-106 - - - - - - - -
NEKGAFBM_01735 3.74e-125 - - - V - - - VanZ like family
NEKGAFBM_01736 1.87e-249 - - - V - - - Beta-lactamase
NEKGAFBM_01737 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NEKGAFBM_01738 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEKGAFBM_01739 8.93e-71 - - - S - - - Pfam:DUF59
NEKGAFBM_01740 1.05e-223 ydhF - - S - - - Aldo keto reductase
NEKGAFBM_01741 1.66e-40 - - - FG - - - HIT domain
NEKGAFBM_01742 3.23e-73 - - - FG - - - HIT domain
NEKGAFBM_01743 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
NEKGAFBM_01744 4.29e-101 - - - - - - - -
NEKGAFBM_01745 1.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NEKGAFBM_01746 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
NEKGAFBM_01747 0.0 cadA - - P - - - P-type ATPase
NEKGAFBM_01749 4.21e-158 - - - S - - - YjbR
NEKGAFBM_01750 5.51e-284 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NEKGAFBM_01751 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NEKGAFBM_01752 1.67e-254 glmS2 - - M - - - SIS domain
NEKGAFBM_01753 3.4e-85 - - - K - - - Winged helix DNA-binding domain
NEKGAFBM_01754 2.5e-132 - - - L - - - Integrase
NEKGAFBM_01755 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
NEKGAFBM_01756 5.6e-41 - - - - - - - -
NEKGAFBM_01757 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NEKGAFBM_01758 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEKGAFBM_01759 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NEKGAFBM_01760 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NEKGAFBM_01761 8.79e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEKGAFBM_01762 6.56e-292 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NEKGAFBM_01763 5.8e-291 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEKGAFBM_01764 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
NEKGAFBM_01765 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEKGAFBM_01766 8.19e-39 - - - M - - - Domain of unknown function (DUF5011)
NEKGAFBM_01767 9.07e-22 - - - L ko:K07487 - ko00000 Transposase
NEKGAFBM_01768 2.12e-27 - - - L ko:K07487 - ko00000 Transposase
NEKGAFBM_01770 2.72e-70 - - - K - - - helix_turn_helix, arabinose operon control protein
NEKGAFBM_01772 3.07e-06 - - - D - - - Mycoplasma protein of unknown function, DUF285
NEKGAFBM_01774 2.15e-17 - - - M - - - Domain of unknown function (DUF5011)
NEKGAFBM_01775 2.28e-22 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEKGAFBM_01776 4.32e-16 - - - L - - - Helix-turn-helix domain
NEKGAFBM_01777 2.03e-12 - - - L - - - Helix-turn-helix domain
NEKGAFBM_01780 2.76e-28 - - - S - - - Cell surface protein
NEKGAFBM_01781 1.08e-208 - - - - - - - -
NEKGAFBM_01783 7.43e-28 - - - M - - - domain protein
NEKGAFBM_01784 2.68e-71 - - - M - - - domain protein
NEKGAFBM_01785 1.17e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
NEKGAFBM_01786 4.43e-129 - - - - - - - -
NEKGAFBM_01787 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEKGAFBM_01788 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
NEKGAFBM_01789 1.02e-226 - - - K - - - LysR substrate binding domain
NEKGAFBM_01790 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
NEKGAFBM_01791 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NEKGAFBM_01793 8.03e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_01794 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_01795 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_01796 1.84e-295 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NEKGAFBM_01797 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NEKGAFBM_01798 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NEKGAFBM_01799 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NEKGAFBM_01800 1.17e-135 - - - K - - - transcriptional regulator
NEKGAFBM_01801 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NEKGAFBM_01802 1.49e-63 - - - - - - - -
NEKGAFBM_01803 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
NEKGAFBM_01804 1.76e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEKGAFBM_01805 2.87e-56 - - - - - - - -
NEKGAFBM_01806 3.35e-75 - - - - - - - -
NEKGAFBM_01807 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_01808 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
NEKGAFBM_01809 2.42e-65 - - - - - - - -
NEKGAFBM_01810 2.31e-166 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
NEKGAFBM_01811 0.0 hpk2 - - T - - - Histidine kinase
NEKGAFBM_01812 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
NEKGAFBM_01813 0.0 ydiC - - EGP - - - Major Facilitator
NEKGAFBM_01814 1.55e-55 - - - - - - - -
NEKGAFBM_01815 2.81e-55 - - - - - - - -
NEKGAFBM_01816 2.6e-149 - - - - - - - -
NEKGAFBM_01817 4.02e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NEKGAFBM_01818 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_01819 8.9e-96 ywnA - - K - - - Transcriptional regulator
NEKGAFBM_01820 7.84e-92 - - - - - - - -
NEKGAFBM_01821 6.2e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NEKGAFBM_01822 2.6e-185 - - - - - - - -
NEKGAFBM_01823 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEKGAFBM_01824 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEKGAFBM_01825 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEKGAFBM_01826 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NEKGAFBM_01827 2.21e-56 - - - - - - - -
NEKGAFBM_01828 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
NEKGAFBM_01829 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NEKGAFBM_01830 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NEKGAFBM_01831 1.3e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NEKGAFBM_01832 5.78e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NEKGAFBM_01833 4.3e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
NEKGAFBM_01834 1.82e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
NEKGAFBM_01835 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
NEKGAFBM_01836 2.41e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NEKGAFBM_01837 2.98e-90 - - - - - - - -
NEKGAFBM_01838 1.22e-125 - - - - - - - -
NEKGAFBM_01839 3.43e-66 - - - - - - - -
NEKGAFBM_01840 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NEKGAFBM_01841 1.21e-111 - - - - - - - -
NEKGAFBM_01842 1.06e-281 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NEKGAFBM_01843 1.53e-102 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_01844 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
NEKGAFBM_01845 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEKGAFBM_01846 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEKGAFBM_01847 7.02e-126 - - - K - - - Helix-turn-helix domain
NEKGAFBM_01848 7.88e-283 - - - C - - - FAD dependent oxidoreductase
NEKGAFBM_01849 2.22e-221 - - - P - - - Major Facilitator Superfamily
NEKGAFBM_01850 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEKGAFBM_01851 1.2e-91 - - - - - - - -
NEKGAFBM_01852 3.68e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEKGAFBM_01853 2.16e-201 dkgB - - S - - - reductase
NEKGAFBM_01854 5.84e-115 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NEKGAFBM_01855 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
NEKGAFBM_01856 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEKGAFBM_01857 1.75e-149 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NEKGAFBM_01859 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
NEKGAFBM_01860 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEKGAFBM_01861 6.41e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEKGAFBM_01862 3.81e-18 - - - - - - - -
NEKGAFBM_01863 1.29e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEKGAFBM_01864 8.83e-208 fbpA - - K - - - Domain of unknown function (DUF814)
NEKGAFBM_01865 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
NEKGAFBM_01866 6.33e-46 - - - - - - - -
NEKGAFBM_01867 2.49e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
NEKGAFBM_01868 2.73e-147 pgm1 - - G - - - phosphoglycerate mutase
NEKGAFBM_01869 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NEKGAFBM_01870 3.41e-277 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEKGAFBM_01871 9.25e-103 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEKGAFBM_01872 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEKGAFBM_01873 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEKGAFBM_01874 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NEKGAFBM_01876 0.0 - - - M - - - domain protein
NEKGAFBM_01877 5.99e-213 mleR - - K - - - LysR substrate binding domain
NEKGAFBM_01878 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEKGAFBM_01879 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NEKGAFBM_01880 9.92e-212 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NEKGAFBM_01881 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEKGAFBM_01882 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
NEKGAFBM_01883 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NEKGAFBM_01884 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEKGAFBM_01885 1.8e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NEKGAFBM_01886 1.17e-60 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
NEKGAFBM_01887 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
NEKGAFBM_01888 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NEKGAFBM_01889 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEKGAFBM_01890 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
NEKGAFBM_01891 1.01e-190 malA - - S - - - maltodextrose utilization protein MalA
NEKGAFBM_01892 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEKGAFBM_01893 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKGAFBM_01894 4.69e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEKGAFBM_01895 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
NEKGAFBM_01896 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
NEKGAFBM_01897 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NEKGAFBM_01898 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEKGAFBM_01899 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
NEKGAFBM_01900 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
NEKGAFBM_01901 9.52e-240 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
NEKGAFBM_01902 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
NEKGAFBM_01903 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_01905 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
NEKGAFBM_01906 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
NEKGAFBM_01907 1.39e-151 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NEKGAFBM_01908 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
NEKGAFBM_01909 3.49e-217 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_01910 7.14e-185 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
NEKGAFBM_01911 3.37e-115 - - - - - - - -
NEKGAFBM_01912 3.69e-190 - - - - - - - -
NEKGAFBM_01913 2.69e-183 - - - - - - - -
NEKGAFBM_01914 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
NEKGAFBM_01915 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NEKGAFBM_01917 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
NEKGAFBM_01918 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_01919 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NEKGAFBM_01920 6.49e-268 - - - C - - - Oxidoreductase
NEKGAFBM_01921 0.0 - - - - - - - -
NEKGAFBM_01922 4.03e-132 - - - - - - - -
NEKGAFBM_01923 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NEKGAFBM_01924 7.84e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
NEKGAFBM_01925 6.75e-212 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
NEKGAFBM_01926 2.52e-203 morA - - S - - - reductase
NEKGAFBM_01928 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
NEKGAFBM_01929 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEKGAFBM_01930 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NEKGAFBM_01931 3.73e-104 - - - S - - - Protein of unknown function (DUF3021)
NEKGAFBM_01932 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NEKGAFBM_01933 4.45e-99 - - - K - - - Transcriptional regulator
NEKGAFBM_01934 2.01e-141 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NEKGAFBM_01935 1.37e-29 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NEKGAFBM_01936 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NEKGAFBM_01937 2.94e-191 - - - I - - - Alpha/beta hydrolase family
NEKGAFBM_01938 1e-156 - - - - - - - -
NEKGAFBM_01939 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
NEKGAFBM_01940 3.55e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NEKGAFBM_01941 0.0 - - - L - - - HIRAN domain
NEKGAFBM_01942 8.35e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NEKGAFBM_01943 1.97e-259 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NEKGAFBM_01944 2.68e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NEKGAFBM_01945 3.03e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NEKGAFBM_01946 3.77e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEKGAFBM_01947 3.94e-224 - - - C - - - Zinc-binding dehydrogenase
NEKGAFBM_01948 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
NEKGAFBM_01949 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEKGAFBM_01950 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
NEKGAFBM_01951 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NEKGAFBM_01952 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
NEKGAFBM_01953 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
NEKGAFBM_01954 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
NEKGAFBM_01955 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
NEKGAFBM_01956 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NEKGAFBM_01957 7.11e-165 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKGAFBM_01958 1.67e-54 - - - - - - - -
NEKGAFBM_01959 7.9e-142 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
NEKGAFBM_01960 4.07e-05 - - - - - - - -
NEKGAFBM_01961 4.85e-180 - - - - - - - -
NEKGAFBM_01962 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NEKGAFBM_01963 2.38e-99 - - - - - - - -
NEKGAFBM_01964 9.06e-180 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NEKGAFBM_01965 3.36e-215 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NEKGAFBM_01966 1.71e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NEKGAFBM_01967 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEKGAFBM_01968 3.14e-230 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NEKGAFBM_01969 1.4e-162 - - - S - - - DJ-1/PfpI family
NEKGAFBM_01970 7.65e-121 yfbM - - K - - - FR47-like protein
NEKGAFBM_01971 4.28e-195 - - - EG - - - EamA-like transporter family
NEKGAFBM_01972 1.9e-79 - - - S - - - Protein of unknown function
NEKGAFBM_01973 7.44e-51 - - - S - - - Protein of unknown function
NEKGAFBM_01974 0.0 fusA1 - - J - - - elongation factor G
NEKGAFBM_01975 1.29e-149 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NEKGAFBM_01976 1.67e-220 - - - K - - - WYL domain
NEKGAFBM_01977 3.06e-165 - - - F - - - glutamine amidotransferase
NEKGAFBM_01978 1.65e-106 - - - S - - - ASCH
NEKGAFBM_01979 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
NEKGAFBM_01980 3.97e-174 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEKGAFBM_01981 0.0 - - - S - - - Putative threonine/serine exporter
NEKGAFBM_01982 1.54e-248 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEKGAFBM_01983 3.83e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NEKGAFBM_01984 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
NEKGAFBM_01985 5.07e-157 ydgI - - C - - - Nitroreductase family
NEKGAFBM_01986 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
NEKGAFBM_01987 4.06e-211 - - - S - - - KR domain
NEKGAFBM_01988 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEKGAFBM_01989 2.49e-95 - - - C - - - FMN binding
NEKGAFBM_01990 1.46e-204 - - - K - - - LysR family
NEKGAFBM_01991 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NEKGAFBM_01992 0.0 - - - C - - - FMN_bind
NEKGAFBM_01993 5.25e-149 - - - S - - - Elongation factor G-binding protein, N-terminal
NEKGAFBM_01994 2.02e-85 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
NEKGAFBM_01995 2.24e-155 pnb - - C - - - nitroreductase
NEKGAFBM_01996 3.46e-156 ung2 - - L - - - Uracil-DNA glycosylase
NEKGAFBM_01997 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
NEKGAFBM_01998 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_01999 1.74e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEKGAFBM_02000 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NEKGAFBM_02001 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NEKGAFBM_02002 3.54e-195 yycI - - S - - - YycH protein
NEKGAFBM_02003 1.02e-312 yycH - - S - - - YycH protein
NEKGAFBM_02004 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEKGAFBM_02005 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NEKGAFBM_02007 1.28e-53 - - - - - - - -
NEKGAFBM_02008 2.54e-42 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NEKGAFBM_02009 1.61e-76 - - - - - - - -
NEKGAFBM_02010 2.58e-52 - - - S - - - Phage gp6-like head-tail connector protein
NEKGAFBM_02013 5.35e-266 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NEKGAFBM_02014 3.54e-255 - - - S - - - Phage portal protein
NEKGAFBM_02015 0.000703 - - - - - - - -
NEKGAFBM_02016 0.0 terL - - S - - - overlaps another CDS with the same product name
NEKGAFBM_02017 3.15e-108 - - - L - - - overlaps another CDS with the same product name
NEKGAFBM_02018 7.42e-89 - - - L - - - HNH endonuclease
NEKGAFBM_02019 7.6e-70 - - - S - - - Head-tail joining protein
NEKGAFBM_02021 2.38e-81 - - - - - - - -
NEKGAFBM_02023 0.0 - - - S - - - Virulence-associated protein E
NEKGAFBM_02024 7.99e-183 - - - L - - - DNA replication protein
NEKGAFBM_02025 5.49e-42 - - - - - - - -
NEKGAFBM_02028 1.65e-289 sip - - L - - - Belongs to the 'phage' integrase family
NEKGAFBM_02029 2.54e-50 - - - - - - - -
NEKGAFBM_02030 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
NEKGAFBM_02031 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
NEKGAFBM_02032 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
NEKGAFBM_02033 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NEKGAFBM_02034 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
NEKGAFBM_02036 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NEKGAFBM_02037 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NEKGAFBM_02038 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NEKGAFBM_02039 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NEKGAFBM_02040 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NEKGAFBM_02041 4.2e-127 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEKGAFBM_02042 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEKGAFBM_02044 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEKGAFBM_02045 3.25e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEKGAFBM_02046 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEKGAFBM_02047 4.96e-289 yttB - - EGP - - - Major Facilitator
NEKGAFBM_02048 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NEKGAFBM_02049 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NEKGAFBM_02050 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NEKGAFBM_02051 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEKGAFBM_02052 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NEKGAFBM_02053 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NEKGAFBM_02054 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEKGAFBM_02055 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEKGAFBM_02056 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEKGAFBM_02057 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
NEKGAFBM_02058 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEKGAFBM_02059 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEKGAFBM_02060 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NEKGAFBM_02061 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEKGAFBM_02062 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEKGAFBM_02063 2.26e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
NEKGAFBM_02064 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
NEKGAFBM_02065 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEKGAFBM_02066 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NEKGAFBM_02067 1.31e-143 - - - S - - - Cell surface protein
NEKGAFBM_02068 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
NEKGAFBM_02070 0.0 - - - - - - - -
NEKGAFBM_02071 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NEKGAFBM_02073 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NEKGAFBM_02074 1.67e-79 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
NEKGAFBM_02075 4.02e-203 degV1 - - S - - - DegV family
NEKGAFBM_02076 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
NEKGAFBM_02077 3.79e-181 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
NEKGAFBM_02078 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NEKGAFBM_02079 7.43e-130 padR - - K - - - Virulence activator alpha C-term
NEKGAFBM_02080 2.51e-103 - - - T - - - Universal stress protein family
NEKGAFBM_02081 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NEKGAFBM_02082 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NEKGAFBM_02083 3.87e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEKGAFBM_02084 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NEKGAFBM_02085 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
NEKGAFBM_02086 2.21e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
NEKGAFBM_02087 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NEKGAFBM_02088 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
NEKGAFBM_02089 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
NEKGAFBM_02090 2.5e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
NEKGAFBM_02091 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NEKGAFBM_02092 1.91e-201 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NEKGAFBM_02093 1.48e-247 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
NEKGAFBM_02094 0.0 yknV - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKGAFBM_02095 0.0 mdlA2 - - V ko:K06147 - ko00000,ko02000 ABC transporter
NEKGAFBM_02096 9.5e-200 - - - K - - - helix_turn_helix, arabinose operon control protein
NEKGAFBM_02097 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
NEKGAFBM_02098 1.29e-231 ypdA - - U ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKGAFBM_02099 6.47e-213 lplC - - U ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKGAFBM_02100 0.0 ypcG - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Domain of unknown function (DUF3502)
NEKGAFBM_02101 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
NEKGAFBM_02102 1.71e-139 ypcB - - S - - - integral membrane protein
NEKGAFBM_02103 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEKGAFBM_02104 0.0 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
NEKGAFBM_02105 3.76e-212 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NEKGAFBM_02106 1.09e-275 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEKGAFBM_02107 0.0 ypdD - - G - - - Glycosyl hydrolase family 92
NEKGAFBM_02108 1.54e-247 - - - K - - - Transcriptional regulator
NEKGAFBM_02109 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
NEKGAFBM_02110 0.0 - 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G ko:K01191,ko:K15524,ko:K16869 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Glycosyl hydrolases family 38 N-terminal domain
NEKGAFBM_02111 4.7e-204 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NEKGAFBM_02112 0.0 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEKGAFBM_02113 6.56e-28 - - - - - - - -
NEKGAFBM_02114 3.95e-92 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
NEKGAFBM_02115 9.95e-122 - - - M - - - Glycosyl hydrolases family 25
NEKGAFBM_02118 3.33e-27 - - - M - - - domain protein
NEKGAFBM_02119 4.04e-62 - - - M - - - domain protein
NEKGAFBM_02120 6.08e-184 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NEKGAFBM_02121 3.88e-20 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NEKGAFBM_02122 3.13e-99 - - - L - - - Transposase DDE domain
NEKGAFBM_02123 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NEKGAFBM_02124 7.84e-173 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEKGAFBM_02125 1.58e-81 - - - - - - - -
NEKGAFBM_02126 1.01e-44 - - - L - - - Domain of unknown function (DUF4373)
NEKGAFBM_02127 1.97e-78 - - - - - - - -
NEKGAFBM_02128 1.14e-69 - - - S - - - Bacteriophage Mu Gam like protein
NEKGAFBM_02132 1.28e-102 - - - - - - - -
NEKGAFBM_02133 7.71e-71 - - - - - - - -
NEKGAFBM_02136 1.13e-36 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEKGAFBM_02137 8.29e-51 - - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
NEKGAFBM_02139 2.06e-50 - - - K - - - Helix-turn-helix
NEKGAFBM_02140 1.32e-80 - - - K - - - Helix-turn-helix domain
NEKGAFBM_02141 4.71e-98 - - - E - - - IrrE N-terminal-like domain
NEKGAFBM_02142 5.32e-202 - - - J - - - Domain of unknown function (DUF4041)
NEKGAFBM_02143 1.65e-101 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
NEKGAFBM_02145 1.8e-06 - - - M - - - LysM domain
NEKGAFBM_02148 7.78e-46 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEKGAFBM_02150 9.51e-48 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
NEKGAFBM_02155 2.07e-43 - - - - - - - -
NEKGAFBM_02157 7.71e-278 int3 - - L - - - Belongs to the 'phage' integrase family
NEKGAFBM_02159 1.98e-40 - - - - - - - -
NEKGAFBM_02161 1.28e-51 - - - - - - - -
NEKGAFBM_02162 9.28e-58 - - - - - - - -
NEKGAFBM_02163 1.27e-109 - - - K - - - MarR family
NEKGAFBM_02164 0.0 - - - D - - - nuclear chromosome segregation
NEKGAFBM_02165 0.0 inlJ - - M - - - MucBP domain
NEKGAFBM_02166 6.58e-24 - - - - - - - -
NEKGAFBM_02167 3.26e-24 - - - - - - - -
NEKGAFBM_02168 1.56e-22 - - - - - - - -
NEKGAFBM_02169 1.07e-26 - - - - - - - -
NEKGAFBM_02170 9.35e-24 - - - - - - - -
NEKGAFBM_02171 9.35e-24 - - - - - - - -
NEKGAFBM_02172 9.35e-24 - - - - - - - -
NEKGAFBM_02173 2.16e-26 - - - - - - - -
NEKGAFBM_02174 4.63e-24 - - - - - - - -
NEKGAFBM_02175 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
NEKGAFBM_02176 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEKGAFBM_02177 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02178 2.1e-33 - - - - - - - -
NEKGAFBM_02179 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NEKGAFBM_02180 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
NEKGAFBM_02181 5.23e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
NEKGAFBM_02182 0.0 yclK - - T - - - Histidine kinase
NEKGAFBM_02183 3.41e-172 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NEKGAFBM_02184 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NEKGAFBM_02185 6.12e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NEKGAFBM_02186 2.55e-218 - - - EG - - - EamA-like transporter family
NEKGAFBM_02188 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
NEKGAFBM_02189 1.31e-64 - - - - - - - -
NEKGAFBM_02190 6.83e-274 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
NEKGAFBM_02191 8.05e-178 - - - F - - - NUDIX domain
NEKGAFBM_02192 2.68e-32 - - - - - - - -
NEKGAFBM_02194 8.16e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEKGAFBM_02195 4.27e-223 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
NEKGAFBM_02196 4.17e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
NEKGAFBM_02197 2.29e-48 - - - - - - - -
NEKGAFBM_02198 1.11e-45 - - - - - - - -
NEKGAFBM_02199 4.86e-279 - - - T - - - diguanylate cyclase
NEKGAFBM_02200 0.0 - - - S - - - ABC transporter, ATP-binding protein
NEKGAFBM_02201 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
NEKGAFBM_02202 5.76e-107 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEKGAFBM_02203 9.2e-62 - - - - - - - -
NEKGAFBM_02204 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEKGAFBM_02205 1.46e-239 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEKGAFBM_02206 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
NEKGAFBM_02207 4.12e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
NEKGAFBM_02208 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NEKGAFBM_02209 8.88e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NEKGAFBM_02210 9.31e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_02211 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NEKGAFBM_02212 1.38e-180 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02213 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NEKGAFBM_02214 3.32e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
NEKGAFBM_02215 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
NEKGAFBM_02216 7.09e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NEKGAFBM_02217 2.13e-255 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NEKGAFBM_02218 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
NEKGAFBM_02219 6.12e-78 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NEKGAFBM_02220 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEKGAFBM_02221 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NEKGAFBM_02222 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NEKGAFBM_02223 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NEKGAFBM_02224 1.57e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEKGAFBM_02225 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NEKGAFBM_02226 8.01e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NEKGAFBM_02227 6.46e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
NEKGAFBM_02228 3.72e-283 ysaA - - V - - - RDD family
NEKGAFBM_02229 1.03e-212 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NEKGAFBM_02230 6.7e-74 - - - S - - - Domain of unknown function (DU1801)
NEKGAFBM_02231 4.73e-118 rmeB - - K - - - transcriptional regulator, MerR family
NEKGAFBM_02232 1.01e-189 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEKGAFBM_02233 4.54e-126 - - - J - - - glyoxalase III activity
NEKGAFBM_02234 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEKGAFBM_02235 2.83e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEKGAFBM_02236 1.45e-46 - - - - - - - -
NEKGAFBM_02237 1.26e-143 - - - S - - - Protein of unknown function (DUF1211)
NEKGAFBM_02238 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NEKGAFBM_02239 0.0 - - - M - - - domain protein
NEKGAFBM_02240 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
NEKGAFBM_02241 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEKGAFBM_02242 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
NEKGAFBM_02243 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NEKGAFBM_02244 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEKGAFBM_02245 1.07e-247 - - - S - - - domain, Protein
NEKGAFBM_02246 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
NEKGAFBM_02247 1.22e-126 - - - C - - - Nitroreductase family
NEKGAFBM_02248 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
NEKGAFBM_02249 3.45e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEKGAFBM_02250 2.2e-157 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEKGAFBM_02251 1.22e-200 ccpB - - K - - - lacI family
NEKGAFBM_02252 4.16e-150 - - - K - - - Helix-turn-helix domain, rpiR family
NEKGAFBM_02253 1.18e-225 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NEKGAFBM_02254 8.97e-253 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
NEKGAFBM_02255 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
NEKGAFBM_02256 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEKGAFBM_02257 9.38e-139 pncA - - Q - - - Isochorismatase family
NEKGAFBM_02258 2.66e-172 - - - - - - - -
NEKGAFBM_02259 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_02260 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
NEKGAFBM_02261 7.2e-61 - - - S - - - Enterocin A Immunity
NEKGAFBM_02262 3.25e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
NEKGAFBM_02263 0.0 pepF2 - - E - - - Oligopeptidase F
NEKGAFBM_02264 1.4e-95 - - - K - - - Transcriptional regulator
NEKGAFBM_02265 1.86e-210 - - - - - - - -
NEKGAFBM_02266 1.23e-75 - - - - - - - -
NEKGAFBM_02267 2.22e-51 - - - - - - - -
NEKGAFBM_02268 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEKGAFBM_02269 1.17e-88 - - - - - - - -
NEKGAFBM_02270 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
NEKGAFBM_02271 9.89e-74 ytpP - - CO - - - Thioredoxin
NEKGAFBM_02272 3.87e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
NEKGAFBM_02273 3.89e-62 - - - - - - - -
NEKGAFBM_02274 2.16e-63 - - - - - - - -
NEKGAFBM_02275 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
NEKGAFBM_02276 4.05e-98 - - - - - - - -
NEKGAFBM_02277 4.15e-78 - - - - - - - -
NEKGAFBM_02278 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NEKGAFBM_02279 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
NEKGAFBM_02280 1.02e-102 uspA3 - - T - - - universal stress protein
NEKGAFBM_02281 8.36e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NEKGAFBM_02282 2.73e-24 - - - - - - - -
NEKGAFBM_02283 1.09e-55 - - - S - - - zinc-ribbon domain
NEKGAFBM_02284 9.66e-97 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NEKGAFBM_02285 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEKGAFBM_02286 3.96e-30 - - - S - - - Protein of unknown function (DUF2929)
NEKGAFBM_02287 1.85e-285 - - - M - - - Glycosyl transferases group 1
NEKGAFBM_02288 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NEKGAFBM_02289 2.25e-206 - - - S - - - Putative esterase
NEKGAFBM_02290 3.53e-169 - - - K - - - Transcriptional regulator
NEKGAFBM_02291 6.74e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEKGAFBM_02292 2.77e-175 - - - - - - - -
NEKGAFBM_02293 1.97e-150 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEKGAFBM_02294 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
NEKGAFBM_02295 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
NEKGAFBM_02296 1.55e-79 - - - - - - - -
NEKGAFBM_02297 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NEKGAFBM_02298 2.97e-76 - - - - - - - -
NEKGAFBM_02299 0.0 yhdP - - S - - - Transporter associated domain
NEKGAFBM_02300 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NEKGAFBM_02301 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NEKGAFBM_02302 3.36e-270 yttB - - EGP - - - Major Facilitator
NEKGAFBM_02303 1.92e-80 - - - K - - - helix_turn_helix, mercury resistance
NEKGAFBM_02304 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
NEKGAFBM_02305 4.71e-74 - - - S - - - SdpI/YhfL protein family
NEKGAFBM_02306 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEKGAFBM_02307 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
NEKGAFBM_02308 2.91e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEKGAFBM_02309 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEKGAFBM_02310 3.59e-26 - - - - - - - -
NEKGAFBM_02311 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
NEKGAFBM_02312 5.73e-208 mleR - - K - - - LysR family
NEKGAFBM_02313 1.29e-148 - - - GM - - - NAD(P)H-binding
NEKGAFBM_02314 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
NEKGAFBM_02315 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NEKGAFBM_02316 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NEKGAFBM_02317 4.54e-216 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
NEKGAFBM_02318 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEKGAFBM_02319 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NEKGAFBM_02320 4.24e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEKGAFBM_02321 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NEKGAFBM_02322 4.77e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NEKGAFBM_02323 2.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEKGAFBM_02324 1.42e-219 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NEKGAFBM_02325 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEKGAFBM_02326 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
NEKGAFBM_02327 4.41e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NEKGAFBM_02328 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
NEKGAFBM_02329 4.71e-208 - - - GM - - - NmrA-like family
NEKGAFBM_02330 1.25e-199 - - - T - - - EAL domain
NEKGAFBM_02331 1.85e-121 - - - - - - - -
NEKGAFBM_02332 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
NEKGAFBM_02333 3.85e-159 - - - E - - - Methionine synthase
NEKGAFBM_02334 6.66e-281 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NEKGAFBM_02335 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NEKGAFBM_02336 1.79e-131 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NEKGAFBM_02337 1.04e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NEKGAFBM_02338 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEKGAFBM_02339 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEKGAFBM_02340 2.82e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEKGAFBM_02341 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEKGAFBM_02342 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NEKGAFBM_02343 3.35e-269 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEKGAFBM_02344 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEKGAFBM_02345 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NEKGAFBM_02346 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
NEKGAFBM_02347 1.16e-242 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
NEKGAFBM_02348 2.04e-189 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEKGAFBM_02349 3.44e-152 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
NEKGAFBM_02350 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEKGAFBM_02351 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NEKGAFBM_02352 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02353 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEKGAFBM_02354 4.76e-56 - - - - - - - -
NEKGAFBM_02355 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
NEKGAFBM_02356 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02357 5.66e-189 - - - - - - - -
NEKGAFBM_02358 2.7e-104 usp5 - - T - - - universal stress protein
NEKGAFBM_02359 1.08e-47 - - - - - - - -
NEKGAFBM_02360 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
NEKGAFBM_02361 1.02e-113 - - - - - - - -
NEKGAFBM_02362 1.4e-65 - - - - - - - -
NEKGAFBM_02363 4.79e-13 - - - - - - - -
NEKGAFBM_02364 2.49e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NEKGAFBM_02365 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
NEKGAFBM_02366 1.52e-151 - - - - - - - -
NEKGAFBM_02367 1.21e-69 - - - - - - - -
NEKGAFBM_02369 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NEKGAFBM_02370 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NEKGAFBM_02371 1.1e-184 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEKGAFBM_02372 2.38e-37 - - - S - - - Pentapeptide repeats (8 copies)
NEKGAFBM_02373 1.44e-142 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NEKGAFBM_02374 5.38e-131 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NEKGAFBM_02375 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
NEKGAFBM_02376 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NEKGAFBM_02377 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
NEKGAFBM_02378 6.01e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NEKGAFBM_02379 4.43e-294 - - - S - - - Sterol carrier protein domain
NEKGAFBM_02380 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
NEKGAFBM_02381 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEKGAFBM_02382 2.13e-152 - - - K - - - Transcriptional regulator
NEKGAFBM_02383 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_02384 1.23e-172 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NEKGAFBM_02385 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NEKGAFBM_02386 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEKGAFBM_02387 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEKGAFBM_02388 2.73e-73 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
NEKGAFBM_02389 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEKGAFBM_02390 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
NEKGAFBM_02391 1.4e-181 epsV - - S - - - glycosyl transferase family 2
NEKGAFBM_02392 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
NEKGAFBM_02393 7.63e-107 - - - - - - - -
NEKGAFBM_02394 5.06e-196 - - - S - - - hydrolase
NEKGAFBM_02395 6.14e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEKGAFBM_02396 2.8e-204 - - - EG - - - EamA-like transporter family
NEKGAFBM_02397 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NEKGAFBM_02398 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NEKGAFBM_02399 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
NEKGAFBM_02400 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
NEKGAFBM_02401 0.0 - - - M - - - Domain of unknown function (DUF5011)
NEKGAFBM_02402 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
NEKGAFBM_02403 4.3e-44 - - - - - - - -
NEKGAFBM_02404 2.89e-165 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
NEKGAFBM_02405 0.0 ycaM - - E - - - amino acid
NEKGAFBM_02406 2.45e-101 - - - K - - - Winged helix DNA-binding domain
NEKGAFBM_02407 1.42e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
NEKGAFBM_02408 5.11e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEKGAFBM_02409 1.07e-208 - - - K - - - Transcriptional regulator
NEKGAFBM_02413 2.72e-126 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEKGAFBM_02414 1.46e-60 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEKGAFBM_02415 1.05e-179 - - - K - - - DeoR C terminal sensor domain
NEKGAFBM_02416 3.4e-229 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
NEKGAFBM_02417 4.67e-314 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NEKGAFBM_02418 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NEKGAFBM_02419 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NEKGAFBM_02420 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
NEKGAFBM_02421 1.31e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NEKGAFBM_02422 1.69e-161 - - - S - - - Membrane
NEKGAFBM_02423 4.04e-94 yueI - - S - - - Protein of unknown function (DUF1694)
NEKGAFBM_02424 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEKGAFBM_02425 5.03e-95 - - - K - - - Transcriptional regulator
NEKGAFBM_02426 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEKGAFBM_02427 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NEKGAFBM_02429 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
NEKGAFBM_02430 1.51e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
NEKGAFBM_02431 9.62e-19 - - - - - - - -
NEKGAFBM_02432 3.78e-212 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEKGAFBM_02433 4.29e-173 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEKGAFBM_02434 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
NEKGAFBM_02435 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
NEKGAFBM_02436 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
NEKGAFBM_02437 1.06e-16 - - - - - - - -
NEKGAFBM_02438 1.22e-115 - - - T - - - ECF transporter, substrate-specific component
NEKGAFBM_02439 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
NEKGAFBM_02440 7.62e-290 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
NEKGAFBM_02441 5.02e-158 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NEKGAFBM_02442 3.44e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
NEKGAFBM_02443 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEKGAFBM_02444 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
NEKGAFBM_02445 1.06e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NEKGAFBM_02446 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NEKGAFBM_02447 6.83e-133 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NEKGAFBM_02448 1.73e-93 - - - S - - - Protein of unknown function (DUF1694)
NEKGAFBM_02449 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NEKGAFBM_02450 3.05e-161 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
NEKGAFBM_02451 3.99e-106 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEKGAFBM_02452 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEKGAFBM_02453 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEKGAFBM_02454 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
NEKGAFBM_02455 4.53e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
NEKGAFBM_02456 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEKGAFBM_02457 6.42e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEKGAFBM_02458 7.29e-61 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
NEKGAFBM_02459 1.17e-305 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEKGAFBM_02460 8.34e-147 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NEKGAFBM_02461 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NEKGAFBM_02462 2.58e-186 yxeH - - S - - - hydrolase
NEKGAFBM_02463 8.95e-225 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEKGAFBM_02465 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
NEKGAFBM_02466 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NEKGAFBM_02467 5.13e-220 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
NEKGAFBM_02468 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NEKGAFBM_02469 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEKGAFBM_02470 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEKGAFBM_02471 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEKGAFBM_02472 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEKGAFBM_02473 3.25e-252 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
NEKGAFBM_02474 8.71e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NEKGAFBM_02475 2.42e-315 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEKGAFBM_02476 7.03e-178 yleF - - K - - - Helix-turn-helix domain, rpiR family
NEKGAFBM_02477 1.48e-103 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEKGAFBM_02478 1.17e-96 - - - G ko:K11201 - ko00000,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEKGAFBM_02479 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEKGAFBM_02480 4.72e-286 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
NEKGAFBM_02481 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEKGAFBM_02482 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEKGAFBM_02483 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEKGAFBM_02484 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEKGAFBM_02485 2.26e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NEKGAFBM_02486 1.76e-204 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
NEKGAFBM_02487 7.2e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NEKGAFBM_02488 0.0 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_02489 5.44e-174 - - - K - - - UTRA domain
NEKGAFBM_02490 2.63e-200 estA - - S - - - Putative esterase
NEKGAFBM_02491 2.09e-83 - - - - - - - -
NEKGAFBM_02492 1.12e-262 - - - EGP - - - Major Facilitator Superfamily
NEKGAFBM_02493 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
NEKGAFBM_02494 9.22e-211 - - - G - - - Xylose isomerase-like TIM barrel
NEKGAFBM_02495 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NEKGAFBM_02496 8.13e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEKGAFBM_02497 1.71e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEKGAFBM_02498 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
NEKGAFBM_02499 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
NEKGAFBM_02500 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEKGAFBM_02501 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NEKGAFBM_02502 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEKGAFBM_02503 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEKGAFBM_02504 4.07e-85 - - - S - - - pyridoxamine 5-phosphate
NEKGAFBM_02505 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
NEKGAFBM_02506 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NEKGAFBM_02507 4.27e-253 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NEKGAFBM_02508 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NEKGAFBM_02509 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NEKGAFBM_02510 2.72e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
NEKGAFBM_02511 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NEKGAFBM_02512 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NEKGAFBM_02513 5.14e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NEKGAFBM_02514 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NEKGAFBM_02515 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NEKGAFBM_02516 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NEKGAFBM_02517 1.59e-129 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NEKGAFBM_02518 7.48e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
NEKGAFBM_02519 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
NEKGAFBM_02520 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NEKGAFBM_02521 3.03e-295 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NEKGAFBM_02522 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NEKGAFBM_02523 4.73e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NEKGAFBM_02524 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
NEKGAFBM_02525 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NEKGAFBM_02526 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NEKGAFBM_02527 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
NEKGAFBM_02528 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEKGAFBM_02529 4.03e-283 - - - S - - - associated with various cellular activities
NEKGAFBM_02530 9.34e-317 - - - S - - - Putative metallopeptidase domain
NEKGAFBM_02531 1.03e-65 - - - - - - - -
NEKGAFBM_02532 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
NEKGAFBM_02533 7.83e-60 - - - - - - - -
NEKGAFBM_02534 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
NEKGAFBM_02535 2.48e-159 - - - S - - - WxL domain surface cell wall-binding
NEKGAFBM_02536 1.83e-235 - - - S - - - Cell surface protein
NEKGAFBM_02537 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NEKGAFBM_02538 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NEKGAFBM_02539 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEKGAFBM_02540 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NEKGAFBM_02541 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
NEKGAFBM_02542 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
NEKGAFBM_02543 7.94e-124 dpsB - - P - - - Belongs to the Dps family
NEKGAFBM_02544 1.01e-26 - - - - - - - -
NEKGAFBM_02545 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
NEKGAFBM_02546 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
NEKGAFBM_02547 8.08e-184 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEKGAFBM_02548 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NEKGAFBM_02549 3.28e-231 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NEKGAFBM_02550 1.44e-163 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
NEKGAFBM_02551 4.86e-174 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NEKGAFBM_02552 5.05e-232 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NEKGAFBM_02553 1.72e-129 - - - K - - - transcriptional regulator
NEKGAFBM_02554 4.61e-204 - - - S ko:K07045 - ko00000 Amidohydrolase
NEKGAFBM_02555 1.22e-68 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
NEKGAFBM_02556 5.13e-138 - - - - - - - -
NEKGAFBM_02558 5.77e-81 - - - - - - - -
NEKGAFBM_02559 2.15e-71 - - - - - - - -
NEKGAFBM_02560 7.65e-104 - - - M - - - PFAM NLP P60 protein
NEKGAFBM_02561 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
NEKGAFBM_02562 4.45e-38 - - - - - - - -
NEKGAFBM_02563 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NEKGAFBM_02564 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_02565 5.33e-114 - - - K - - - Winged helix DNA-binding domain
NEKGAFBM_02566 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
NEKGAFBM_02567 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
NEKGAFBM_02568 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
NEKGAFBM_02569 0.0 - - - - - - - -
NEKGAFBM_02570 3.42e-212 - - - S - - - Protein of unknown function (DUF1002)
NEKGAFBM_02571 1.58e-66 - - - - - - - -
NEKGAFBM_02572 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
NEKGAFBM_02573 6.94e-117 ymdB - - S - - - Macro domain protein
NEKGAFBM_02574 5.43e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NEKGAFBM_02575 3.68e-57 - - - S - - - Protein of unknown function (DUF1093)
NEKGAFBM_02576 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
NEKGAFBM_02577 2.57e-171 - - - S - - - Putative threonine/serine exporter
NEKGAFBM_02578 1.36e-209 yvgN - - C - - - Aldo keto reductase
NEKGAFBM_02579 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NEKGAFBM_02580 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NEKGAFBM_02581 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
NEKGAFBM_02582 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NEKGAFBM_02583 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
NEKGAFBM_02584 5.99e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
NEKGAFBM_02585 5.09e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NEKGAFBM_02586 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NEKGAFBM_02587 8.75e-85 - - - S - - - Protein of unknown function (DUF1398)
NEKGAFBM_02588 1.04e-64 - - - - - - - -
NEKGAFBM_02589 7.21e-35 - - - - - - - -
NEKGAFBM_02590 1.77e-314 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
NEKGAFBM_02591 3.43e-96 - - - S - - - COG NOG18757 non supervised orthologous group
NEKGAFBM_02592 4.26e-54 - - - - - - - -
NEKGAFBM_02593 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NEKGAFBM_02594 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NEKGAFBM_02595 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NEKGAFBM_02596 2.55e-145 - - - S - - - VIT family
NEKGAFBM_02597 2.66e-155 - - - S - - - membrane
NEKGAFBM_02598 1.63e-203 - - - EG - - - EamA-like transporter family
NEKGAFBM_02599 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
NEKGAFBM_02600 3.57e-150 - - - GM - - - NmrA-like family
NEKGAFBM_02601 4.79e-21 - - - - - - - -
NEKGAFBM_02602 9.27e-74 - - - - - - - -
NEKGAFBM_02603 4.58e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NEKGAFBM_02604 1.11e-111 - - - - - - - -
NEKGAFBM_02605 2.11e-82 - - - - - - - -
NEKGAFBM_02606 7.08e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
NEKGAFBM_02607 1.7e-70 - - - - - - - -
NEKGAFBM_02608 1.41e-86 yeaO - - S - - - Protein of unknown function, DUF488
NEKGAFBM_02609 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
NEKGAFBM_02610 2.14e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
NEKGAFBM_02611 1.12e-208 - - - GM - - - NmrA-like family
NEKGAFBM_02612 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
NEKGAFBM_02613 2.65e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEKGAFBM_02614 9.04e-317 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NEKGAFBM_02615 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NEKGAFBM_02616 3.58e-36 - - - S - - - Belongs to the LOG family
NEKGAFBM_02617 9e-179 - - - C - - - C4-dicarboxylate transmembrane transporter activity
NEKGAFBM_02618 2.51e-150 - - - GM - - - NAD(P)H-binding
NEKGAFBM_02619 1.6e-118 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NEKGAFBM_02620 5.51e-101 yphH - - S - - - Cupin domain
NEKGAFBM_02621 2.06e-78 - - - I - - - sulfurtransferase activity
NEKGAFBM_02622 5.44e-178 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
NEKGAFBM_02623 8.38e-152 - - - GM - - - NAD(P)H-binding
NEKGAFBM_02624 2.31e-277 - - - - - - - -
NEKGAFBM_02625 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKGAFBM_02626 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02627 1.51e-225 - - - O - - - protein import
NEKGAFBM_02628 1.67e-292 amd - - E - - - Peptidase family M20/M25/M40
NEKGAFBM_02629 2.43e-208 yhxD - - IQ - - - KR domain
NEKGAFBM_02631 9.38e-91 - - - - - - - -
NEKGAFBM_02632 1.74e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
NEKGAFBM_02633 0.0 - - - E - - - Amino Acid
NEKGAFBM_02634 1.67e-86 lysM - - M - - - LysM domain
NEKGAFBM_02635 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
NEKGAFBM_02636 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
NEKGAFBM_02637 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NEKGAFBM_02638 3.65e-59 - - - S - - - Cupredoxin-like domain
NEKGAFBM_02639 1.36e-84 - - - S - - - Cupredoxin-like domain
NEKGAFBM_02640 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NEKGAFBM_02641 2.81e-181 - - - K - - - Helix-turn-helix domain
NEKGAFBM_02642 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
NEKGAFBM_02643 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEKGAFBM_02644 0.0 - - - - - - - -
NEKGAFBM_02645 1.56e-98 - - - - - - - -
NEKGAFBM_02646 1.11e-240 - - - S - - - Cell surface protein
NEKGAFBM_02647 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
NEKGAFBM_02648 9.33e-226 - - - C - - - Alcohol dehydrogenase GroES-like domain
NEKGAFBM_02649 1.22e-88 - - - S - - - Iron-sulphur cluster biosynthesis
NEKGAFBM_02650 3.33e-149 - - - S - - - GyrI-like small molecule binding domain
NEKGAFBM_02651 8.98e-244 ynjC - - S - - - Cell surface protein
NEKGAFBM_02652 2.7e-131 - - - S - - - WxL domain surface cell wall-binding
NEKGAFBM_02653 1.47e-83 - - - - - - - -
NEKGAFBM_02654 2.07e-311 - - - NU - - - Mycoplasma protein of unknown function, DUF285
NEKGAFBM_02655 4.13e-157 - - - - - - - -
NEKGAFBM_02656 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
NEKGAFBM_02657 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
NEKGAFBM_02658 1.81e-272 - - - EGP - - - Major Facilitator
NEKGAFBM_02659 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
NEKGAFBM_02660 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NEKGAFBM_02661 8.01e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEKGAFBM_02662 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEKGAFBM_02663 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_02664 2.18e-215 - - - GM - - - NmrA-like family
NEKGAFBM_02665 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NEKGAFBM_02666 0.0 - - - M - - - Glycosyl hydrolases family 25
NEKGAFBM_02667 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
NEKGAFBM_02668 2.56e-83 - - - K - - - HxlR-like helix-turn-helix
NEKGAFBM_02669 2.69e-169 - - - S - - - KR domain
NEKGAFBM_02670 5.79e-126 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_02671 5.76e-243 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
NEKGAFBM_02672 7.34e-129 - - - S - - - Protein of unknown function (DUF1211)
NEKGAFBM_02673 6.6e-228 ydhF - - S - - - Aldo keto reductase
NEKGAFBM_02674 0.0 yfjF - - U - - - Sugar (and other) transporter
NEKGAFBM_02675 1.08e-140 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_02676 7.05e-219 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NEKGAFBM_02677 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEKGAFBM_02678 1.81e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEKGAFBM_02679 1.35e-218 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEKGAFBM_02680 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_02681 3.2e-209 - - - GM - - - NmrA-like family
NEKGAFBM_02682 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEKGAFBM_02683 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
NEKGAFBM_02684 1.83e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NEKGAFBM_02685 3.86e-85 - - - K - - - helix_turn_helix, mercury resistance
NEKGAFBM_02686 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEKGAFBM_02687 3.51e-232 - - - S - - - Bacterial protein of unknown function (DUF916)
NEKGAFBM_02688 1.87e-107 - - - S - - - WxL domain surface cell wall-binding
NEKGAFBM_02689 1.86e-265 - - - NU - - - Mycoplasma protein of unknown function, DUF285
NEKGAFBM_02690 1.97e-151 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_02691 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEKGAFBM_02692 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
NEKGAFBM_02693 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
NEKGAFBM_02694 2.72e-208 - - - K - - - LysR substrate binding domain
NEKGAFBM_02695 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEKGAFBM_02696 0.0 - - - S - - - MucBP domain
NEKGAFBM_02697 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NEKGAFBM_02698 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
NEKGAFBM_02699 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEKGAFBM_02700 9.2e-317 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_02701 2.09e-85 - - - - - - - -
NEKGAFBM_02702 5.15e-16 - - - - - - - -
NEKGAFBM_02703 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NEKGAFBM_02704 4.83e-31 - - - K - - - helix_turn_helix, mercury resistance
NEKGAFBM_02705 5.98e-85 - - - S - - - Protein of unknown function (DUF1093)
NEKGAFBM_02706 8.12e-282 - - - S - - - Membrane
NEKGAFBM_02707 1.04e-59 - - - S - - - Protein of unknown function (DUF3781)
NEKGAFBM_02708 3.1e-138 yoaZ - - S - - - intracellular protease amidase
NEKGAFBM_02709 1.35e-55 - - - K - - - HxlR-like helix-turn-helix
NEKGAFBM_02710 9.66e-77 - - - - - - - -
NEKGAFBM_02711 2.06e-81 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_02712 5.31e-66 - - - K - - - Helix-turn-helix domain
NEKGAFBM_02713 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
NEKGAFBM_02714 3.64e-47 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NEKGAFBM_02715 1.44e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
NEKGAFBM_02716 8.09e-142 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEKGAFBM_02717 1.93e-139 - - - GM - - - NAD(P)H-binding
NEKGAFBM_02718 5.35e-102 - - - GM - - - SnoaL-like domain
NEKGAFBM_02719 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
NEKGAFBM_02720 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
NEKGAFBM_02721 7.9e-136 - - - K - - - Bacterial regulatory proteins, tetR family
NEKGAFBM_02722 1.34e-05 - - - L ko:K07483 - ko00000 transposase activity
NEKGAFBM_02723 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
NEKGAFBM_02725 6.79e-53 - - - - - - - -
NEKGAFBM_02726 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEKGAFBM_02727 9.26e-233 ydbI - - K - - - AI-2E family transporter
NEKGAFBM_02728 7.62e-270 xylR - - GK - - - ROK family
NEKGAFBM_02729 4.93e-149 - - - - - - - -
NEKGAFBM_02730 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NEKGAFBM_02731 2e-211 - - - - - - - -
NEKGAFBM_02732 1.94e-258 pkn2 - - KLT - - - Protein tyrosine kinase
NEKGAFBM_02733 5.03e-37 - - - S - - - Protein of unknown function (DUF4064)
NEKGAFBM_02734 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
NEKGAFBM_02735 9.69e-99 - - - S - - - Psort location Cytoplasmic, score
NEKGAFBM_02737 5.01e-71 - - - - - - - -
NEKGAFBM_02738 1.37e-140 - - - S ko:K07090 - ko00000 membrane transporter protein
NEKGAFBM_02739 5.93e-73 - - - S - - - branched-chain amino acid
NEKGAFBM_02740 2.05e-167 - - - E - - - branched-chain amino acid
NEKGAFBM_02741 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NEKGAFBM_02742 5.36e-305 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NEKGAFBM_02743 5.61e-273 hpk31 - - T - - - Histidine kinase
NEKGAFBM_02744 1.62e-159 vanR - - K - - - response regulator
NEKGAFBM_02745 9.76e-159 - - - S - - - Protein of unknown function (DUF1275)
NEKGAFBM_02746 3.84e-207 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEKGAFBM_02747 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEKGAFBM_02748 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
NEKGAFBM_02749 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEKGAFBM_02750 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NEKGAFBM_02751 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NEKGAFBM_02752 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NEKGAFBM_02753 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NEKGAFBM_02754 1.81e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NEKGAFBM_02755 3.35e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
NEKGAFBM_02756 3.45e-198 - - - S - - - Bacterial membrane protein, YfhO
NEKGAFBM_02757 2.12e-188 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEKGAFBM_02758 1.37e-215 - - - K - - - LysR substrate binding domain
NEKGAFBM_02759 1.2e-301 - - - EK - - - Aminotransferase, class I
NEKGAFBM_02760 1.11e-169 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NEKGAFBM_02761 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKGAFBM_02762 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02763 1.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NEKGAFBM_02764 8.83e-127 - - - KT - - - response to antibiotic
NEKGAFBM_02765 8.52e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
NEKGAFBM_02766 4.95e-132 - - - S - - - Protein of unknown function (DUF1700)
NEKGAFBM_02767 1.53e-198 - - - S - - - Putative adhesin
NEKGAFBM_02768 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEKGAFBM_02769 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEKGAFBM_02770 2.6e-233 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NEKGAFBM_02771 3.73e-263 - - - S - - - DUF218 domain
NEKGAFBM_02772 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NEKGAFBM_02773 2.93e-151 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02774 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEKGAFBM_02775 6.26e-101 - - - - - - - -
NEKGAFBM_02776 6.9e-197 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
NEKGAFBM_02777 3.03e-191 - - - S - - - haloacid dehalogenase-like hydrolase
NEKGAFBM_02778 1.29e-115 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NEKGAFBM_02779 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
NEKGAFBM_02780 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
NEKGAFBM_02781 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEKGAFBM_02782 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
NEKGAFBM_02783 2.11e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEKGAFBM_02784 4.08e-101 - - - K - - - MerR family regulatory protein
NEKGAFBM_02785 2.16e-199 - - - GM - - - NmrA-like family
NEKGAFBM_02786 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEKGAFBM_02787 1.25e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
NEKGAFBM_02789 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
NEKGAFBM_02790 8.44e-304 - - - S - - - module of peptide synthetase
NEKGAFBM_02791 3.32e-135 - - - - - - - -
NEKGAFBM_02792 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NEKGAFBM_02793 1.28e-77 - - - S - - - Enterocin A Immunity
NEKGAFBM_02794 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
NEKGAFBM_02795 7.93e-217 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
NEKGAFBM_02796 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
NEKGAFBM_02797 4.14e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
NEKGAFBM_02798 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
NEKGAFBM_02799 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
NEKGAFBM_02800 1.03e-34 - - - - - - - -
NEKGAFBM_02801 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
NEKGAFBM_02802 1.97e-110 - - - S - - - Pfam:DUF3816
NEKGAFBM_02803 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEKGAFBM_02804 1.54e-144 - - - - - - - -
NEKGAFBM_02805 2.94e-227 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEKGAFBM_02806 3.84e-185 - - - S - - - Peptidase_C39 like family
NEKGAFBM_02807 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
NEKGAFBM_02808 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NEKGAFBM_02809 9.38e-189 - - - KT - - - helix_turn_helix, mercury resistance
NEKGAFBM_02810 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEKGAFBM_02811 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NEKGAFBM_02812 1.2e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEKGAFBM_02813 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02814 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
NEKGAFBM_02815 2e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
NEKGAFBM_02816 3.55e-127 ywjB - - H - - - RibD C-terminal domain
NEKGAFBM_02817 1.97e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEKGAFBM_02818 9.01e-155 - - - S - - - Membrane
NEKGAFBM_02819 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
NEKGAFBM_02820 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
NEKGAFBM_02821 3.46e-251 - - - EGP - - - Major Facilitator Superfamily
NEKGAFBM_02822 5.73e-139 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NEKGAFBM_02823 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NEKGAFBM_02824 5.97e-106 - - - S - - - Domain of unknown function (DUF4811)
NEKGAFBM_02825 7.69e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEKGAFBM_02826 2.17e-222 - - - S - - - Conserved hypothetical protein 698
NEKGAFBM_02827 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NEKGAFBM_02828 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
NEKGAFBM_02829 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEKGAFBM_02831 9.92e-88 - - - M - - - LysM domain
NEKGAFBM_02832 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
NEKGAFBM_02833 9.97e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02834 2.26e-268 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEKGAFBM_02835 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEKGAFBM_02836 1.16e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NEKGAFBM_02837 4.77e-100 yphH - - S - - - Cupin domain
NEKGAFBM_02838 7.37e-103 - - - K - - - transcriptional regulator, MerR family
NEKGAFBM_02839 1.3e-63 - - - H - - - RibD C-terminal domain
NEKGAFBM_02841 1.46e-299 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NEKGAFBM_02842 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEKGAFBM_02843 1.74e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02845 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEKGAFBM_02846 4.33e-139 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NEKGAFBM_02847 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NEKGAFBM_02848 1.58e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NEKGAFBM_02849 9.82e-111 - - - - - - - -
NEKGAFBM_02850 4.4e-112 yvbK - - K - - - GNAT family
NEKGAFBM_02851 2.8e-49 - - - - - - - -
NEKGAFBM_02852 2.81e-64 - - - - - - - -
NEKGAFBM_02853 5.46e-145 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
NEKGAFBM_02854 2.65e-78 - - - S - - - Domain of unknown function (DUF4440)
NEKGAFBM_02855 1.57e-202 - - - K - - - LysR substrate binding domain
NEKGAFBM_02856 2.53e-134 - - - GM - - - NAD(P)H-binding
NEKGAFBM_02857 2.88e-248 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NEKGAFBM_02858 5.85e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NEKGAFBM_02859 1.2e-181 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEKGAFBM_02860 4.83e-105 - - - S - - - Protein of unknown function (DUF1211)
NEKGAFBM_02861 2.14e-98 - - - C - - - Flavodoxin
NEKGAFBM_02862 2.78e-160 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
NEKGAFBM_02863 1.43e-114 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NEKGAFBM_02864 7.8e-113 - - - GM - - - NAD(P)H-binding
NEKGAFBM_02865 2.11e-132 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEKGAFBM_02866 5.63e-98 - - - K - - - Transcriptional regulator
NEKGAFBM_02868 1.03e-31 - - - C - - - Flavodoxin
NEKGAFBM_02869 1.69e-08 adhR - - K - - - helix_turn_helix, mercury resistance
NEKGAFBM_02870 9.99e-147 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEKGAFBM_02871 2.81e-164 - - - C - - - Aldo keto reductase
NEKGAFBM_02872 4.02e-181 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEKGAFBM_02873 3.08e-178 - - - EGP ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
NEKGAFBM_02874 5.55e-106 - - - GM - - - NAD(P)H-binding
NEKGAFBM_02875 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
NEKGAFBM_02876 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NEKGAFBM_02877 1.19e-160 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NEKGAFBM_02878 1.12e-105 - - - - - - - -
NEKGAFBM_02879 3.73e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NEKGAFBM_02880 3.45e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NEKGAFBM_02881 1.52e-131 - - - M - - - Protein of unknown function (DUF3737)
NEKGAFBM_02882 4.96e-247 - - - C - - - Aldo/keto reductase family
NEKGAFBM_02884 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKGAFBM_02885 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKGAFBM_02886 7.46e-313 - - - EGP - - - Major Facilitator
NEKGAFBM_02889 6.17e-317 yhgE - - V ko:K01421 - ko00000 domain protein
NEKGAFBM_02890 1.59e-143 - - - K - - - Transcriptional regulator (TetR family)
NEKGAFBM_02891 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEKGAFBM_02892 1.66e-199 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NEKGAFBM_02893 1.06e-138 yokL3 - - J - - - Acetyltransferase (GNAT) domain
NEKGAFBM_02894 3.05e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEKGAFBM_02895 9.53e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_02896 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NEKGAFBM_02897 5.46e-189 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NEKGAFBM_02898 0.0 - - - S - - - Predicted membrane protein (DUF2207)
NEKGAFBM_02899 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
NEKGAFBM_02900 2.33e-265 - - - EGP - - - Major facilitator Superfamily
NEKGAFBM_02901 2.67e-220 ropB - - K - - - Helix-turn-helix XRE-family like proteins
NEKGAFBM_02902 1.76e-298 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NEKGAFBM_02903 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
NEKGAFBM_02904 1.36e-204 - - - I - - - alpha/beta hydrolase fold
NEKGAFBM_02905 1.75e-168 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NEKGAFBM_02906 0.0 - - - - - - - -
NEKGAFBM_02907 2e-52 - - - S - - - Cytochrome B5
NEKGAFBM_02908 5.02e-117 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEKGAFBM_02909 2.39e-278 - - - T - - - Diguanylate cyclase, GGDEF domain
NEKGAFBM_02910 2.82e-163 - - - T - - - Putative diguanylate phosphodiesterase
NEKGAFBM_02911 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEKGAFBM_02912 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NEKGAFBM_02913 1.56e-108 - - - - - - - -
NEKGAFBM_02914 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NEKGAFBM_02915 5.32e-242 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEKGAFBM_02916 2.09e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEKGAFBM_02917 3.7e-30 - - - - - - - -
NEKGAFBM_02918 1.84e-134 - - - - - - - -
NEKGAFBM_02919 5.12e-212 - - - K - - - LysR substrate binding domain
NEKGAFBM_02920 1.24e-313 - - - P - - - Sodium:sulfate symporter transmembrane region
NEKGAFBM_02921 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NEKGAFBM_02922 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NEKGAFBM_02923 1.37e-182 - - - S - - - zinc-ribbon domain
NEKGAFBM_02925 4.29e-50 - - - - - - - -
NEKGAFBM_02926 1.48e-171 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
NEKGAFBM_02927 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NEKGAFBM_02928 0.0 - - - I - - - acetylesterase activity
NEKGAFBM_02929 1.99e-297 - - - M - - - Collagen binding domain
NEKGAFBM_02930 6.92e-206 yicL - - EG - - - EamA-like transporter family
NEKGAFBM_02931 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
NEKGAFBM_02932 1.44e-226 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
NEKGAFBM_02933 1.98e-142 - - - K - - - Transcriptional regulator C-terminal region
NEKGAFBM_02934 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
NEKGAFBM_02935 8.78e-206 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NEKGAFBM_02936 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NEKGAFBM_02937 6.37e-125 - - - K - - - Transcriptional regulator, MarR family
NEKGAFBM_02938 3.29e-153 ydgI3 - - C - - - Nitroreductase family
NEKGAFBM_02939 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEKGAFBM_02940 7.52e-139 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKGAFBM_02941 2.76e-196 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NEKGAFBM_02942 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NEKGAFBM_02943 0.0 - - - - - - - -
NEKGAFBM_02944 3.08e-80 - - - - - - - -
NEKGAFBM_02945 7.52e-240 - - - S - - - Cell surface protein
NEKGAFBM_02946 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
NEKGAFBM_02947 1.91e-124 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NEKGAFBM_02948 1.61e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKGAFBM_02949 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
NEKGAFBM_02950 3.79e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NEKGAFBM_02951 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NEKGAFBM_02952 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
NEKGAFBM_02954 1.15e-43 - - - - - - - -
NEKGAFBM_02955 6.9e-168 zmp3 - - O - - - Zinc-dependent metalloprotease
NEKGAFBM_02956 2.88e-106 gtcA3 - - S - - - GtrA-like protein
NEKGAFBM_02957 2.19e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
NEKGAFBM_02958 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NEKGAFBM_02959 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
NEKGAFBM_02960 2.87e-61 - - - - - - - -
NEKGAFBM_02961 1.04e-149 - - - S - - - SNARE associated Golgi protein
NEKGAFBM_02962 8.58e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NEKGAFBM_02963 7.89e-124 - - - P - - - Cadmium resistance transporter
NEKGAFBM_02964 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_02965 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
NEKGAFBM_02966 2.03e-84 - - - - - - - -
NEKGAFBM_02967 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NEKGAFBM_02968 2.86e-72 - - - - - - - -
NEKGAFBM_02969 8.38e-193 - - - K - - - Helix-turn-helix domain
NEKGAFBM_02970 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEKGAFBM_02971 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEKGAFBM_02972 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_02973 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEKGAFBM_02974 7.48e-236 - - - GM - - - Male sterility protein
NEKGAFBM_02975 4.4e-101 - - - K - - - helix_turn_helix, mercury resistance
NEKGAFBM_02976 4.61e-101 - - - M - - - LysM domain
NEKGAFBM_02977 3.03e-130 - - - M - - - Lysin motif
NEKGAFBM_02978 1.4e-138 - - - S - - - SdpI/YhfL protein family
NEKGAFBM_02979 1.58e-72 nudA - - S - - - ASCH
NEKGAFBM_02980 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEKGAFBM_02981 3.57e-120 - - - - - - - -
NEKGAFBM_02982 1.92e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
NEKGAFBM_02983 3.55e-281 - - - T - - - diguanylate cyclase
NEKGAFBM_02984 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
NEKGAFBM_02985 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
NEKGAFBM_02986 1.17e-214 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NEKGAFBM_02987 2.14e-95 - - - - - - - -
NEKGAFBM_02988 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEKGAFBM_02989 4.6e-46 - - - C - - - C4-dicarboxylate transmembrane transporter activity
NEKGAFBM_02990 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NEKGAFBM_02991 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEKGAFBM_02992 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NEKGAFBM_02993 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEKGAFBM_02994 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NEKGAFBM_02995 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEKGAFBM_02996 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
NEKGAFBM_02997 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NEKGAFBM_02999 7.72e-57 yabO - - J - - - S4 domain protein
NEKGAFBM_03000 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NEKGAFBM_03001 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEKGAFBM_03002 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEKGAFBM_03003 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NEKGAFBM_03004 0.0 - - - S - - - Putative peptidoglycan binding domain
NEKGAFBM_03005 4.87e-148 - - - S - - - (CBS) domain
NEKGAFBM_03006 5.3e-110 queT - - S - - - QueT transporter
NEKGAFBM_03007 1.85e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEKGAFBM_03008 4.47e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
NEKGAFBM_03009 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NEKGAFBM_03010 1.38e-293 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NEKGAFBM_03011 1.72e-242 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NEKGAFBM_03012 1.51e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NEKGAFBM_03013 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NEKGAFBM_03014 2.02e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NEKGAFBM_03015 4.3e-202 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKGAFBM_03016 1.37e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
NEKGAFBM_03017 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NEKGAFBM_03018 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NEKGAFBM_03019 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEKGAFBM_03020 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEKGAFBM_03021 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NEKGAFBM_03022 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEKGAFBM_03023 1.84e-189 - - - - - - - -
NEKGAFBM_03024 5.58e-195 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NEKGAFBM_03025 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
NEKGAFBM_03026 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NEKGAFBM_03027 1.49e-273 - - - J - - - translation release factor activity
NEKGAFBM_03028 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NEKGAFBM_03029 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEKGAFBM_03030 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEKGAFBM_03031 2.41e-37 - - - - - - - -
NEKGAFBM_03032 4.45e-168 - - - S - - - YheO-like PAS domain
NEKGAFBM_03033 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NEKGAFBM_03034 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NEKGAFBM_03035 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
NEKGAFBM_03036 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEKGAFBM_03037 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEKGAFBM_03038 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NEKGAFBM_03039 1.66e-100 ywiB - - S - - - Domain of unknown function (DUF1934)
NEKGAFBM_03040 6.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
NEKGAFBM_03041 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
NEKGAFBM_03042 4.15e-191 yxeH - - S - - - hydrolase
NEKGAFBM_03043 7.12e-178 - - - - - - - -
NEKGAFBM_03044 1.15e-235 - - - S - - - DUF218 domain
NEKGAFBM_03045 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEKGAFBM_03046 1.1e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NEKGAFBM_03047 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEKGAFBM_03048 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NEKGAFBM_03049 5.3e-49 - - - - - - - -
NEKGAFBM_03050 2.4e-56 - - - S - - - ankyrin repeats
NEKGAFBM_03051 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NEKGAFBM_03052 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEKGAFBM_03053 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
NEKGAFBM_03054 5.32e-208 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEKGAFBM_03055 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
NEKGAFBM_03056 2.5e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEKGAFBM_03057 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NEKGAFBM_03058 6.64e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NEKGAFBM_03059 4.08e-270 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
NEKGAFBM_03060 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEKGAFBM_03061 4.64e-92 - - - F - - - DNA mismatch repair protein MutT
NEKGAFBM_03062 3.74e-204 yunF - - F - - - Protein of unknown function DUF72
NEKGAFBM_03063 1.24e-170 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
NEKGAFBM_03064 1.82e-226 - - - - - - - -
NEKGAFBM_03065 1.32e-288 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NEKGAFBM_03066 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NEKGAFBM_03067 4.17e-193 - - - S - - - Psort location Cytoplasmic, score
NEKGAFBM_03068 4.1e-261 - - - - - - - -
NEKGAFBM_03069 5.68e-242 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEKGAFBM_03070 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
NEKGAFBM_03071 4.21e-210 - - - GK - - - ROK family
NEKGAFBM_03072 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEKGAFBM_03073 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_03074 7.17e-99 - - - S - - - Domain of unknown function (DUF3284)
NEKGAFBM_03075 9.68e-34 - - - - - - - -
NEKGAFBM_03076 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKGAFBM_03077 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
NEKGAFBM_03078 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEKGAFBM_03079 3.54e-182 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
NEKGAFBM_03080 0.0 - - - L - - - DNA helicase
NEKGAFBM_03081 1.85e-40 - - - - - - - -
NEKGAFBM_03082 3.34e-147 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_03083 2.75e-145 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_03084 5.04e-155 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_03085 3.26e-124 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_03086 1.49e-309 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
NEKGAFBM_03087 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NEKGAFBM_03088 8.82e-32 - - - - - - - -
NEKGAFBM_03089 1.93e-31 plnF - - - - - - -
NEKGAFBM_03090 1.35e-165 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEKGAFBM_03091 1.05e-173 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEKGAFBM_03092 2.48e-172 sppR - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEKGAFBM_03093 2.08e-301 plnB 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEKGAFBM_03094 2.23e-24 plnA - - - - - - -
NEKGAFBM_03095 1.22e-36 - - - - - - - -
NEKGAFBM_03096 1.09e-149 - - - - - - - -
NEKGAFBM_03099 1.82e-56 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEKGAFBM_03103 1.39e-261 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEKGAFBM_03104 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NEKGAFBM_03105 8.38e-192 - - - S - - - hydrolase
NEKGAFBM_03106 2.35e-212 - - - K - - - Transcriptional regulator
NEKGAFBM_03107 4.15e-188 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NEKGAFBM_03108 1.19e-257 - - - EGP - - - Transporter, major facilitator family protein
NEKGAFBM_03109 2.64e-153 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NEKGAFBM_03110 5.32e-51 - - - - - - - -
NEKGAFBM_03111 6.97e-45 - - - - - - - -
NEKGAFBM_03113 7.37e-08 - - - - - - - -
NEKGAFBM_03114 1.84e-105 - - - S - - - Phage transcriptional regulator, ArpU family
NEKGAFBM_03118 3.97e-25 - - - - - - - -
NEKGAFBM_03120 1.86e-108 - - - L ko:K07474 - ko00000 Terminase small subunit
NEKGAFBM_03121 2.95e-304 - - - S - - - Terminase-like family
NEKGAFBM_03122 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
NEKGAFBM_03123 0.0 - - - S - - - Phage Mu protein F like protein
NEKGAFBM_03124 3.05e-41 - - - - - - - -
NEKGAFBM_03127 5.72e-64 - - - - - - - -
NEKGAFBM_03128 2.08e-222 - - - S - - - Phage major capsid protein E
NEKGAFBM_03130 2.9e-68 - - - - - - - -
NEKGAFBM_03131 9.63e-68 - - - - - - - -
NEKGAFBM_03132 5.34e-115 - - - - - - - -
NEKGAFBM_03133 3.49e-72 - - - - - - - -
NEKGAFBM_03134 7.42e-102 - - - S - - - Phage tail tube protein, TTP
NEKGAFBM_03135 1.42e-83 - - - - - - - -
NEKGAFBM_03136 0.0 - - - D - - - domain protein
NEKGAFBM_03137 2.29e-81 - - - - - - - -
NEKGAFBM_03138 0.0 - - - LM - - - DNA recombination
NEKGAFBM_03139 1.52e-93 - - - S - - - Protein of unknown function (DUF1617)
NEKGAFBM_03141 7.37e-231 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEKGAFBM_03142 1.53e-62 - - - - - - - -
NEKGAFBM_03143 1.82e-54 - - - S - - - Bacteriophage holin
NEKGAFBM_03146 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
NEKGAFBM_03147 2.12e-84 yxeA - - S - - - Protein of unknown function (DUF1093)
NEKGAFBM_03148 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEKGAFBM_03149 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NEKGAFBM_03150 5.37e-182 - - - - - - - -
NEKGAFBM_03151 1.33e-77 - - - - - - - -
NEKGAFBM_03152 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NEKGAFBM_03153 8.57e-41 - - - - - - - -
NEKGAFBM_03154 1.12e-246 ampC - - V - - - Beta-lactamase
NEKGAFBM_03155 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NEKGAFBM_03156 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NEKGAFBM_03157 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
NEKGAFBM_03158 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NEKGAFBM_03159 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEKGAFBM_03160 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEKGAFBM_03161 4.39e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NEKGAFBM_03162 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEKGAFBM_03163 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEKGAFBM_03164 2.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NEKGAFBM_03165 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NEKGAFBM_03166 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEKGAFBM_03167 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEKGAFBM_03168 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEKGAFBM_03169 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEKGAFBM_03170 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEKGAFBM_03171 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEKGAFBM_03172 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NEKGAFBM_03173 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEKGAFBM_03174 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEKGAFBM_03175 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NEKGAFBM_03176 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NEKGAFBM_03177 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
NEKGAFBM_03178 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NEKGAFBM_03179 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
NEKGAFBM_03180 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEKGAFBM_03181 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEKGAFBM_03182 1.23e-190 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NEKGAFBM_03183 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NEKGAFBM_03184 1.88e-226 - - - S - - - Protein of unknown function (DUF2785)
NEKGAFBM_03185 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NEKGAFBM_03186 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NEKGAFBM_03187 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NEKGAFBM_03188 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
NEKGAFBM_03189 1.91e-259 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NEKGAFBM_03190 2.37e-107 uspA - - T - - - universal stress protein
NEKGAFBM_03191 1.34e-52 - - - - - - - -
NEKGAFBM_03192 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NEKGAFBM_03193 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NEKGAFBM_03194 1.31e-119 - - - K - - - Periplasmic binding proteins and sugar binding domain of LacI family
NEKGAFBM_03195 4.42e-84 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEKGAFBM_03196 4.54e-132 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NEKGAFBM_03197 5.82e-139 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
NEKGAFBM_03198 3.43e-55 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NEKGAFBM_03199 3.95e-288 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NEKGAFBM_03200 4.54e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEKGAFBM_03201 5.26e-141 - - - S - - - Protein of unknown function (DUF1648)
NEKGAFBM_03202 2.82e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NEKGAFBM_03203 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
NEKGAFBM_03204 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEKGAFBM_03205 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NEKGAFBM_03206 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NEKGAFBM_03207 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NEKGAFBM_03208 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)