ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MCCBHEMI_00001 4.08e-269 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
MCCBHEMI_00002 7.52e-214 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
MCCBHEMI_00003 9.24e-83 cgeA - - - ko:K06319 - ko00000 -
MCCBHEMI_00004 8.16e-54 cgeC - - - ko:K06321 - ko00000 -
MCCBHEMI_00005 3.49e-288 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
MCCBHEMI_00006 1.61e-175 yiiD - - K ko:K06323 - ko00000 acetyltransferase
MCCBHEMI_00008 2.99e-35 - - - L - - - Bacterial transcription activator, effector binding domain
MCCBHEMI_00010 7.19e-298 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MCCBHEMI_00011 1.81e-156 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MCCBHEMI_00012 3.36e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MCCBHEMI_00013 1.92e-316 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
MCCBHEMI_00014 7.16e-182 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
MCCBHEMI_00015 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
MCCBHEMI_00016 6.45e-59 yokU - - S - - - YokU-like protein, putative antitoxin
MCCBHEMI_00017 2.87e-47 yozE - - S - - - Belongs to the UPF0346 family
MCCBHEMI_00018 2.7e-66 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCCBHEMI_00019 1.18e-155 yodN - - - - - - -
MCCBHEMI_00021 1.97e-33 yozD - - S - - - YozD-like protein
MCCBHEMI_00022 1.39e-129 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MCCBHEMI_00023 1.16e-72 yodL - - S - - - YodL-like
MCCBHEMI_00025 1.23e-160 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MCCBHEMI_00026 1.5e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MCCBHEMI_00027 2.3e-30 yodI - - - - - - -
MCCBHEMI_00028 1.37e-153 yodH - - Q - - - Methyltransferase
MCCBHEMI_00029 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MCCBHEMI_00030 6.29e-163 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_00031 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MCCBHEMI_00032 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
MCCBHEMI_00033 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MCCBHEMI_00034 1.14e-27 - - - S - - - Protein of unknown function (DUF3311)
MCCBHEMI_00035 3.08e-212 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MCCBHEMI_00036 9.49e-138 yahD - - S ko:K06999 - ko00000 Carboxylesterase
MCCBHEMI_00037 7.47e-136 yodC - - C - - - nitroreductase
MCCBHEMI_00038 2.74e-69 yodB - - K - - - transcriptional
MCCBHEMI_00039 3.82e-82 iolK - - S - - - tautomerase
MCCBHEMI_00041 2.14e-100 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
MCCBHEMI_00042 3.04e-203 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
MCCBHEMI_00043 9e-32 - - - - - - - -
MCCBHEMI_00044 4.69e-79 yojF - - S - - - Protein of unknown function (DUF1806)
MCCBHEMI_00045 3.71e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
MCCBHEMI_00046 8.86e-187 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MCCBHEMI_00047 8.71e-297 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
MCCBHEMI_00049 3.97e-136 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MCCBHEMI_00050 2.93e-279 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
MCCBHEMI_00051 3.95e-275 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MCCBHEMI_00052 4.38e-134 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MCCBHEMI_00053 9.9e-208 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
MCCBHEMI_00054 0.0 yojO - - P - - - Von Willebrand factor
MCCBHEMI_00055 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MCCBHEMI_00056 1.12e-257 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MCCBHEMI_00057 1.31e-163 - - - S - - - Metallo-beta-lactamase superfamily
MCCBHEMI_00058 4.7e-201 yocS - - S ko:K03453 - ko00000 -transporter
MCCBHEMI_00059 7.69e-294 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MCCBHEMI_00060 5.12e-207 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
MCCBHEMI_00061 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
MCCBHEMI_00062 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MCCBHEMI_00063 4.69e-43 yozC - - - - - - -
MCCBHEMI_00064 5.32e-75 yozO - - S - - - Bacterial PH domain
MCCBHEMI_00065 1.83e-49 yocN - - - - - - -
MCCBHEMI_00066 1.13e-58 yozN - - - - - - -
MCCBHEMI_00067 2.21e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MCCBHEMI_00068 2.34e-11 yocN - - - - - - -
MCCBHEMI_00070 6.39e-79 yocK - - T - - - general stress protein
MCCBHEMI_00071 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MCCBHEMI_00073 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MCCBHEMI_00074 2.09e-162 yocH - - M - - - COG1388 FOG LysM repeat
MCCBHEMI_00076 1.39e-233 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
MCCBHEMI_00077 3.63e-120 yocC - - - - - - -
MCCBHEMI_00078 9.94e-172 - - - J - - - Protein required for attachment to host cells
MCCBHEMI_00079 5.42e-117 yozB - - S ko:K08976 - ko00000 membrane
MCCBHEMI_00080 1.34e-154 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MCCBHEMI_00081 7.69e-73 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
MCCBHEMI_00082 1.29e-117 yobW - - - - - - -
MCCBHEMI_00083 6.03e-160 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MCCBHEMI_00084 3.13e-109 yobS - - K - - - Transcriptional regulator
MCCBHEMI_00085 1.54e-156 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
MCCBHEMI_00086 3.53e-69 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
MCCBHEMI_00087 5.55e-39 - - - K - - - Helix-turn-helix XRE-family like proteins
MCCBHEMI_00088 6.73e-35 - - - S - - - DNA binding
MCCBHEMI_00094 1.67e-234 - - - - - - - -
MCCBHEMI_00097 5.16e-13 - - - - - - - -
MCCBHEMI_00102 4.71e-10 - - - L ko:K07451 - ko00000,ko01000,ko02048 COG1403 Restriction endonuclease
MCCBHEMI_00103 6.23e-19 - - - - - - - -
MCCBHEMI_00107 1.41e-58 - - - L - - - Terminase, small subunit
MCCBHEMI_00108 8.69e-271 terL - - S - - - Terminase
MCCBHEMI_00109 0.000941 - - - - - - - -
MCCBHEMI_00110 3.19e-181 - - - S - - - portal protein
MCCBHEMI_00111 4.88e-69 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
MCCBHEMI_00112 2.19e-128 - - - S - - - capsid protein
MCCBHEMI_00113 3.92e-29 - - - S - - - Phage gp6-like head-tail connector protein
MCCBHEMI_00114 1.41e-26 - - - S - - - Phage head-tail joining protein
MCCBHEMI_00115 1.36e-42 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MCCBHEMI_00120 0.0 - - - D - - - Phage tail tape measure protein
MCCBHEMI_00122 7.15e-123 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
MCCBHEMI_00123 0.0 - - - M - - - Pectate lyase superfamily protein
MCCBHEMI_00124 3.19e-100 - - - S - - - Domain of unknown function (DUF2479)
MCCBHEMI_00127 3.66e-37 bhlA - - S - - - BhlA holin family
MCCBHEMI_00128 4.18e-35 xhlB - - S - - - SPP1 phage holin
MCCBHEMI_00129 1.02e-58 - - - M - - - D-alanyl-D-alanine carboxypeptidase
MCCBHEMI_00131 2.5e-12 - - - K - - - Helix-turn-helix domain
MCCBHEMI_00134 1.17e-14 - - - K - - - Transcriptional regulator
MCCBHEMI_00139 1.32e-139 - - - L - - - Belongs to the 'phage' integrase family
MCCBHEMI_00144 0.0 - - - V - - - Beta-lactamase
MCCBHEMI_00148 3.54e-43 yoaF - - - - - - -
MCCBHEMI_00149 5.17e-35 yoaF - - - - - - -
MCCBHEMI_00150 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MCCBHEMI_00151 5.9e-238 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCCBHEMI_00152 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
MCCBHEMI_00153 7.14e-263 yoaB - - EGP - - - the major facilitator superfamily
MCCBHEMI_00154 9.83e-147 yoxB - - - - - - -
MCCBHEMI_00155 1.68e-47 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MCCBHEMI_00156 4.03e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MCCBHEMI_00157 6.69e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MCCBHEMI_00158 6.04e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MCCBHEMI_00159 2.89e-252 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MCCBHEMI_00160 1.63e-202 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_00161 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
MCCBHEMI_00162 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MCCBHEMI_00163 1.01e-60 - - - S - - - Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MCCBHEMI_00164 6.27e-224 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MCCBHEMI_00165 2.45e-188 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_00166 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MCCBHEMI_00167 1.91e-66 - - - K - - - Helix-turn-helix domain
MCCBHEMI_00168 6.35e-245 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
MCCBHEMI_00169 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MCCBHEMI_00170 7.83e-46 yoeD - - G - - - Helix-turn-helix domain
MCCBHEMI_00171 7.69e-123 - - - L - - - Integrase
MCCBHEMI_00173 8.33e-122 yoeB - - S - - - IseA DL-endopeptidase inhibitor
MCCBHEMI_00174 1.26e-303 yoeA - - V - - - MATE efflux family protein
MCCBHEMI_00175 6.1e-227 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MCCBHEMI_00176 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MCCBHEMI_00177 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCCBHEMI_00178 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
MCCBHEMI_00179 1.09e-81 yngL - - S - - - Protein of unknown function (DUF1360)
MCCBHEMI_00180 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
MCCBHEMI_00181 6.97e-264 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MCCBHEMI_00182 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MCCBHEMI_00183 4.57e-304 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
MCCBHEMI_00184 2.28e-40 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
MCCBHEMI_00185 1.3e-209 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
MCCBHEMI_00186 1.47e-170 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
MCCBHEMI_00187 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MCCBHEMI_00188 6.22e-134 yngC - - S - - - SNARE associated Golgi protein
MCCBHEMI_00189 2.89e-196 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MCCBHEMI_00190 7.19e-89 yngA - - S - - - membrane
MCCBHEMI_00191 4.08e-171 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MCCBHEMI_00192 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MCCBHEMI_00193 1.21e-251 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MCCBHEMI_00194 6.05e-157 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MCCBHEMI_00195 6.98e-241 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MCCBHEMI_00196 6.2e-207 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MCCBHEMI_00197 4.69e-145 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MCCBHEMI_00198 2.24e-136 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MCCBHEMI_00199 2.09e-155 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MCCBHEMI_00200 1.91e-262 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MCCBHEMI_00201 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCCBHEMI_00202 6.4e-303 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCCBHEMI_00203 1.41e-303 - 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
MCCBHEMI_00204 1.84e-155 - - - T - - - Transcriptional regulatory protein, C terminal
MCCBHEMI_00205 1.28e-284 - - - T - - - Histidine kinase
MCCBHEMI_00206 1.01e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
MCCBHEMI_00207 6.72e-145 yndJ - - S - - - YndJ-like protein
MCCBHEMI_00208 8.9e-101 - - - S - - - Domain of unknown function (DUF4166)
MCCBHEMI_00209 2.43e-175 yndG - - S - - - DoxX-like family
MCCBHEMI_00210 1.76e-316 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MCCBHEMI_00211 2.04e-60 ynfC - - - - - - -
MCCBHEMI_00212 2.21e-19 - - - - - - - -
MCCBHEMI_00213 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MCCBHEMI_00214 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MCCBHEMI_00215 1.41e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
MCCBHEMI_00216 1.51e-119 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MCCBHEMI_00217 3.27e-58 yneR - - S - - - Belongs to the HesB IscA family
MCCBHEMI_00218 1.41e-63 yneQ - - - - - - -
MCCBHEMI_00219 3.3e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MCCBHEMI_00220 6.03e-45 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
MCCBHEMI_00222 2.66e-09 - - - S - - - Fur-regulated basic protein B
MCCBHEMI_00223 4.36e-114 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MCCBHEMI_00224 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MCCBHEMI_00225 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
MCCBHEMI_00226 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
MCCBHEMI_00227 4.56e-78 cotM - - O ko:K06335 - ko00000 Spore coat protein
MCCBHEMI_00228 5.21e-93 yneK - - S - - - Protein of unknown function (DUF2621)
MCCBHEMI_00229 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
MCCBHEMI_00230 4.11e-75 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
MCCBHEMI_00231 1.38e-158 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
MCCBHEMI_00232 8.06e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
MCCBHEMI_00233 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MCCBHEMI_00234 8.2e-102 yneE - - S - - - Sporulation inhibitor of replication protein sirA
MCCBHEMI_00235 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MCCBHEMI_00236 4.7e-43 ynzC - - S - - - UPF0291 protein
MCCBHEMI_00237 5.84e-142 yneB - - L - - - resolvase
MCCBHEMI_00238 1.13e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MCCBHEMI_00239 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MCCBHEMI_00241 3.69e-85 yndM - - S - - - Protein of unknown function (DUF2512)
MCCBHEMI_00242 6.02e-183 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
MCCBHEMI_00243 4.12e-10 - - - - - - - -
MCCBHEMI_00244 1.08e-163 yndL - - S - - - Replication protein
MCCBHEMI_00245 1.38e-98 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
MCCBHEMI_00246 1.33e-43 - - - S - - - TM2 domain
MCCBHEMI_00247 0.0 yobO - - M - - - Pectate lyase superfamily protein
MCCBHEMI_00249 1.97e-119 yvgO - - - - - - -
MCCBHEMI_00250 9.32e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MCCBHEMI_00251 7.85e-151 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
MCCBHEMI_00252 1.9e-238 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCCBHEMI_00253 2.39e-130 - - - S - - - Domain of unknown function (DUF3885)
MCCBHEMI_00257 9.33e-119 - - - J - - - Acetyltransferase (GNAT) domain
MCCBHEMI_00258 2.18e-169 yoaP - - K - - - YoaP-like
MCCBHEMI_00259 6.05e-14 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MCCBHEMI_00261 1.07e-41 - - - S - - - Protein of unknown function (DUF4025)
MCCBHEMI_00262 2.04e-10 - - - - - - - -
MCCBHEMI_00264 2.48e-229 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MCCBHEMI_00265 1.95e-89 dinB - - S - - - DinB family
MCCBHEMI_00267 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
MCCBHEMI_00268 7.67e-151 - 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MCCBHEMI_00269 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
MCCBHEMI_00270 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MCCBHEMI_00271 1.45e-261 xylR - - GK - - - ROK family
MCCBHEMI_00272 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MCCBHEMI_00273 4.86e-313 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
MCCBHEMI_00274 2.55e-270 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MCCBHEMI_00275 2.32e-151 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MCCBHEMI_00276 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MCCBHEMI_00277 8.18e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
MCCBHEMI_00278 2.18e-306 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MCCBHEMI_00279 1.17e-289 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MCCBHEMI_00280 2.58e-225 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
MCCBHEMI_00281 3.32e-136 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MCCBHEMI_00282 8.99e-132 ymaB - - S - - - MutT family
MCCBHEMI_00283 5.94e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCCBHEMI_00284 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCCBHEMI_00285 4.43e-77 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MCCBHEMI_00286 9.42e-29 ymzA - - - - - - -
MCCBHEMI_00287 1.87e-53 - - - - - - - -
MCCBHEMI_00288 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MCCBHEMI_00289 1.3e-212 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MCCBHEMI_00290 9.08e-72 ymaF - - S - - - YmaF family
MCCBHEMI_00292 3.36e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MCCBHEMI_00293 1.76e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MCCBHEMI_00294 7.54e-99 ymaD - - O - - - redox protein, regulator of disulfide bond formation
MCCBHEMI_00295 3.75e-152 ymaC - - S - - - Replication protein
MCCBHEMI_00296 2.64e-07 - - - - - - - -
MCCBHEMI_00297 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
MCCBHEMI_00298 9.32e-81 ymzB - - - - - - -
MCCBHEMI_00299 6.09e-150 yoaK - - S - - - Membrane
MCCBHEMI_00300 4.98e-92 nucB - - M - - - Deoxyribonuclease NucA/NucB
MCCBHEMI_00301 1.58e-283 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MCCBHEMI_00302 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
MCCBHEMI_00303 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MCCBHEMI_00304 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MCCBHEMI_00305 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MCCBHEMI_00306 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MCCBHEMI_00307 6.35e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
MCCBHEMI_00308 4.28e-178 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
MCCBHEMI_00309 2.45e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
MCCBHEMI_00310 6.16e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
MCCBHEMI_00311 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MCCBHEMI_00312 6.19e-216 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
MCCBHEMI_00313 1.77e-202 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MCCBHEMI_00314 6.19e-161 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
MCCBHEMI_00315 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MCCBHEMI_00316 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MCCBHEMI_00317 3.93e-116 cotE - - S ko:K06328 - ko00000 Spore coat protein
MCCBHEMI_00318 2.03e-86 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
MCCBHEMI_00319 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MCCBHEMI_00320 1.95e-271 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MCCBHEMI_00321 7.95e-249 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MCCBHEMI_00322 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
MCCBHEMI_00323 3.06e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
MCCBHEMI_00324 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MCCBHEMI_00325 3.54e-259 pbpX - - V - - - Beta-lactamase
MCCBHEMI_00326 8.4e-237 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MCCBHEMI_00327 1.81e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MCCBHEMI_00328 2.26e-130 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MCCBHEMI_00329 2.03e-169 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
MCCBHEMI_00330 1.28e-182 ymfK - - S - - - Protein of unknown function (DUF3388)
MCCBHEMI_00331 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
MCCBHEMI_00332 6.51e-161 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MCCBHEMI_00333 2.54e-304 ymfH - - S - - - zinc protease
MCCBHEMI_00334 3.17e-297 albE - - S - - - Peptidase M16
MCCBHEMI_00335 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
MCCBHEMI_00336 1.58e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MCCBHEMI_00337 2.76e-290 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_00338 9.71e-167 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_00339 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MCCBHEMI_00340 7.4e-41 - - - S - - - YlzJ-like protein
MCCBHEMI_00341 1.89e-167 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
MCCBHEMI_00342 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MCCBHEMI_00343 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MCCBHEMI_00344 1.83e-278 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MCCBHEMI_00345 5.33e-244 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MCCBHEMI_00346 1.2e-131 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MCCBHEMI_00347 1.68e-199 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
MCCBHEMI_00348 2.17e-56 ymxH - - S - - - YlmC YmxH family
MCCBHEMI_00349 9.79e-298 mlpA - - S - - - Belongs to the peptidase M16 family
MCCBHEMI_00350 2.3e-229 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
MCCBHEMI_00351 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MCCBHEMI_00352 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MCCBHEMI_00353 6.31e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MCCBHEMI_00354 2.26e-215 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MCCBHEMI_00355 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MCCBHEMI_00356 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
MCCBHEMI_00357 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MCCBHEMI_00358 6.16e-63 ylxQ - - J - - - ribosomal protein
MCCBHEMI_00359 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
MCCBHEMI_00360 3.32e-263 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MCCBHEMI_00361 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MCCBHEMI_00362 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MCCBHEMI_00363 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MCCBHEMI_00364 4.47e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MCCBHEMI_00365 4.26e-271 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MCCBHEMI_00366 1.48e-176 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MCCBHEMI_00367 2.49e-183 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MCCBHEMI_00368 1.59e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MCCBHEMI_00369 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MCCBHEMI_00370 4.66e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MCCBHEMI_00371 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MCCBHEMI_00372 7.58e-84 ylxL - - - - - - -
MCCBHEMI_00373 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCCBHEMI_00374 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MCCBHEMI_00375 1.39e-141 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MCCBHEMI_00376 1.01e-104 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
MCCBHEMI_00377 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
MCCBHEMI_00378 2.95e-241 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MCCBHEMI_00379 1.18e-195 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
MCCBHEMI_00380 2.58e-223 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
MCCBHEMI_00381 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MCCBHEMI_00382 6.63e-238 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MCCBHEMI_00383 5.49e-166 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
MCCBHEMI_00384 9.02e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
MCCBHEMI_00385 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
MCCBHEMI_00386 6.3e-142 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
MCCBHEMI_00387 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
MCCBHEMI_00388 5.44e-230 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MCCBHEMI_00389 1.28e-228 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MCCBHEMI_00390 3.66e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
MCCBHEMI_00391 2.56e-175 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
MCCBHEMI_00392 2.34e-90 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
MCCBHEMI_00393 2.14e-239 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
MCCBHEMI_00394 3.78e-76 ylxF - - S - - - MgtE intracellular N domain
MCCBHEMI_00395 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
MCCBHEMI_00396 2.02e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MCCBHEMI_00397 4.87e-116 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
MCCBHEMI_00398 3.52e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MCCBHEMI_00399 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
MCCBHEMI_00400 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
MCCBHEMI_00401 1.46e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
MCCBHEMI_00402 3.14e-81 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MCCBHEMI_00403 7.94e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MCCBHEMI_00404 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MCCBHEMI_00405 1.43e-118 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MCCBHEMI_00406 1.42e-216 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
MCCBHEMI_00407 8.65e-311 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MCCBHEMI_00408 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MCCBHEMI_00409 2.16e-208 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
MCCBHEMI_00410 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MCCBHEMI_00411 1.66e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MCCBHEMI_00412 2.83e-58 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
MCCBHEMI_00413 0.0 ylqG - - - - - - -
MCCBHEMI_00414 3.1e-170 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCCBHEMI_00415 5.95e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MCCBHEMI_00416 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MCCBHEMI_00417 7.74e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MCCBHEMI_00418 5.07e-120 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MCCBHEMI_00419 5.66e-79 ylqD - - S - - - YlqD protein
MCCBHEMI_00420 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MCCBHEMI_00421 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MCCBHEMI_00422 2e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MCCBHEMI_00423 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MCCBHEMI_00424 2.09e-221 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MCCBHEMI_00425 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MCCBHEMI_00426 2.48e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MCCBHEMI_00427 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MCCBHEMI_00428 5.81e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MCCBHEMI_00429 2.08e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MCCBHEMI_00430 2.58e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MCCBHEMI_00431 2.96e-119 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MCCBHEMI_00432 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MCCBHEMI_00433 3.97e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MCCBHEMI_00434 1.69e-152 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MCCBHEMI_00435 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
MCCBHEMI_00436 2.12e-77 yloU - - S - - - protein conserved in bacteria
MCCBHEMI_00437 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MCCBHEMI_00438 1.56e-145 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MCCBHEMI_00439 1.69e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MCCBHEMI_00440 2.96e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MCCBHEMI_00441 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MCCBHEMI_00442 2.33e-167 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MCCBHEMI_00443 8.43e-261 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MCCBHEMI_00444 2.41e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MCCBHEMI_00445 6.66e-215 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MCCBHEMI_00446 1.68e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MCCBHEMI_00447 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MCCBHEMI_00448 2.33e-282 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MCCBHEMI_00449 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MCCBHEMI_00450 1.16e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MCCBHEMI_00451 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
MCCBHEMI_00452 8e-194 yloC - - S - - - stress-induced protein
MCCBHEMI_00453 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
MCCBHEMI_00454 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MCCBHEMI_00455 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MCCBHEMI_00456 5.95e-95 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
MCCBHEMI_00457 1.13e-175 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
MCCBHEMI_00458 3.01e-178 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MCCBHEMI_00459 1.31e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MCCBHEMI_00460 2.06e-282 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MCCBHEMI_00461 1.58e-224 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
MCCBHEMI_00462 7.81e-178 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MCCBHEMI_00463 2.88e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MCCBHEMI_00464 1.67e-159 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MCCBHEMI_00465 1.66e-218 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MCCBHEMI_00466 1.61e-177 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MCCBHEMI_00467 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
MCCBHEMI_00468 4.04e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MCCBHEMI_00469 8.28e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MCCBHEMI_00470 7.17e-205 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MCCBHEMI_00471 6.33e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
MCCBHEMI_00472 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MCCBHEMI_00473 7.29e-214 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MCCBHEMI_00474 8.42e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MCCBHEMI_00475 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
MCCBHEMI_00476 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MCCBHEMI_00477 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
MCCBHEMI_00478 4.63e-177 ylmH - - S - - - conserved protein, contains S4-like domain
MCCBHEMI_00479 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
MCCBHEMI_00480 3.54e-84 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MCCBHEMI_00481 2.29e-155 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MCCBHEMI_00482 1.63e-197 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
MCCBHEMI_00483 7.13e-52 ylmC - - S - - - sporulation protein
MCCBHEMI_00484 8.26e-309 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
MCCBHEMI_00485 9e-184 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MCCBHEMI_00486 3.8e-178 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCCBHEMI_00487 3.64e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCCBHEMI_00488 3.59e-212 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MCCBHEMI_00489 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
MCCBHEMI_00490 4.32e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MCCBHEMI_00491 3.7e-297 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MCCBHEMI_00492 3.74e-170 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MCCBHEMI_00493 2.63e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
MCCBHEMI_00494 2.7e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MCCBHEMI_00495 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MCCBHEMI_00496 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MCCBHEMI_00497 2.36e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MCCBHEMI_00498 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MCCBHEMI_00499 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
MCCBHEMI_00500 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MCCBHEMI_00501 2.81e-67 ftsL - - D - - - Essential cell division protein
MCCBHEMI_00502 2.75e-217 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MCCBHEMI_00503 9.34e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MCCBHEMI_00504 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MCCBHEMI_00505 5.92e-195 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MCCBHEMI_00506 2.68e-115 ylbP - - K - - - n-acetyltransferase
MCCBHEMI_00507 3.34e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MCCBHEMI_00508 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MCCBHEMI_00509 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
MCCBHEMI_00510 9.24e-153 ylbM - - S - - - Belongs to the UPF0348 family
MCCBHEMI_00512 7.74e-234 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MCCBHEMI_00513 2.03e-177 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MCCBHEMI_00514 1.92e-266 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
MCCBHEMI_00515 2.38e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MCCBHEMI_00516 4.27e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
MCCBHEMI_00517 4.62e-56 ylbG - - S - - - UPF0298 protein
MCCBHEMI_00518 3.73e-94 ylbF - - S - - - Belongs to the UPF0342 family
MCCBHEMI_00519 1.73e-48 ylbE - - S - - - YlbE-like protein
MCCBHEMI_00520 2.24e-82 ylbD - - S - - - Putative coat protein
MCCBHEMI_00521 4.77e-247 ylbC - - S - - - protein with SCP PR1 domains
MCCBHEMI_00522 1.59e-94 ylbB - - T - - - COG0517 FOG CBS domain
MCCBHEMI_00523 1.96e-77 ylbA - - S - - - YugN-like family
MCCBHEMI_00524 1.91e-207 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
MCCBHEMI_00525 5.01e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MCCBHEMI_00526 3.43e-141 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MCCBHEMI_00527 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MCCBHEMI_00528 6.83e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MCCBHEMI_00529 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MCCBHEMI_00530 1.65e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MCCBHEMI_00531 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MCCBHEMI_00532 3.73e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MCCBHEMI_00533 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
MCCBHEMI_00534 6.76e-217 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MCCBHEMI_00535 7.69e-105 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MCCBHEMI_00536 3.52e-309 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
MCCBHEMI_00537 3.79e-129 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MCCBHEMI_00538 7.95e-45 ylaI - - S - - - protein conserved in bacteria
MCCBHEMI_00539 6.99e-65 - - - S - - - YlaH-like protein
MCCBHEMI_00540 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MCCBHEMI_00541 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
MCCBHEMI_00542 1.62e-56 ylaE - - - - - - -
MCCBHEMI_00544 5.06e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MCCBHEMI_00545 2.21e-51 ylaB - - - - - - -
MCCBHEMI_00546 6.65e-218 ylaA - - - - - - -
MCCBHEMI_00547 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MCCBHEMI_00548 9.54e-102 ykzC - - S - - - Acetyltransferase (GNAT) family
MCCBHEMI_00549 1.57e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
MCCBHEMI_00550 7.89e-32 ykzI - - - - - - -
MCCBHEMI_00551 3.19e-152 yktB - - S - - - Belongs to the UPF0637 family
MCCBHEMI_00552 5.44e-56 yktA - - S - - - Belongs to the UPF0223 family
MCCBHEMI_00553 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
MCCBHEMI_00554 2.74e-172 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MCCBHEMI_00555 6.84e-60 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MCCBHEMI_00556 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MCCBHEMI_00557 1.71e-300 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MCCBHEMI_00558 2.38e-225 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MCCBHEMI_00559 3.17e-260 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MCCBHEMI_00561 7.11e-253 - - - V - - - Beta-lactamase
MCCBHEMI_00562 0.0 - - - IQ - - - Phosphopantetheine attachment site
MCCBHEMI_00563 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MCCBHEMI_00564 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MCCBHEMI_00565 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MCCBHEMI_00566 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MCCBHEMI_00567 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
MCCBHEMI_00568 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MCCBHEMI_00569 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MCCBHEMI_00570 5.02e-121 ykyA - - L - - - Putative cell-wall binding lipoprotein
MCCBHEMI_00571 4.93e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MCCBHEMI_00572 4.45e-128 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MCCBHEMI_00573 1.28e-179 ykrA - - S - - - hydrolases of the HAD superfamily
MCCBHEMI_00574 7.4e-41 ykzG - - S - - - Belongs to the UPF0356 family
MCCBHEMI_00575 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MCCBHEMI_00576 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MCCBHEMI_00577 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MCCBHEMI_00578 3.99e-192 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
MCCBHEMI_00579 3.89e-302 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MCCBHEMI_00580 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
MCCBHEMI_00581 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
MCCBHEMI_00582 7.7e-19 - - - S - - - Uncharacterized protein YkpC
MCCBHEMI_00583 3.85e-299 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
MCCBHEMI_00584 3.4e-202 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MCCBHEMI_00585 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MCCBHEMI_00586 1.02e-47 ykoA - - - - - - -
MCCBHEMI_00587 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MCCBHEMI_00588 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MCCBHEMI_00589 8.8e-210 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
MCCBHEMI_00590 8.9e-168 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_00591 2.73e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MCCBHEMI_00592 1.96e-156 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_00593 1.48e-225 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MCCBHEMI_00594 8.2e-134 yknW - - S - - - Yip1 domain
MCCBHEMI_00595 1.15e-43 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MCCBHEMI_00596 2.06e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
MCCBHEMI_00597 2.52e-110 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
MCCBHEMI_00598 2.09e-304 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
MCCBHEMI_00599 9.1e-237 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MCCBHEMI_00600 3.69e-128 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MCCBHEMI_00601 1.97e-199 yknT - - - ko:K06437 - ko00000 -
MCCBHEMI_00602 3.55e-125 rok - - K - - - Repressor of ComK
MCCBHEMI_00603 3.29e-94 ykuV - - CO - - - thiol-disulfide
MCCBHEMI_00605 3.34e-176 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
MCCBHEMI_00606 1.25e-51 ykuS - - S - - - Belongs to the UPF0180 family
MCCBHEMI_00607 4.07e-269 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MCCBHEMI_00608 4.79e-128 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MCCBHEMI_00609 5.49e-97 fld - - C ko:K03839 - ko00000 Flavodoxin
MCCBHEMI_00610 6.18e-207 ykuO - - - - - - -
MCCBHEMI_00611 4.14e-113 ykuN - - C ko:K03839 - ko00000 Flavodoxin
MCCBHEMI_00612 2.02e-211 ccpC - - K - - - Transcriptional regulator
MCCBHEMI_00613 8.55e-99 ykuL - - S - - - CBS domain
MCCBHEMI_00614 2.63e-36 ykzF - - S - - - Antirepressor AbbA
MCCBHEMI_00615 6.94e-117 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
MCCBHEMI_00616 2.11e-49 ykuJ - - S - - - protein conserved in bacteria
MCCBHEMI_00617 1.74e-293 ykuI - - T - - - Diguanylate phosphodiesterase
MCCBHEMI_00619 4.63e-176 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCCBHEMI_00620 4.21e-187 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
MCCBHEMI_00621 2.01e-113 ykuD - - S - - - protein conserved in bacteria
MCCBHEMI_00622 2e-302 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_00623 1.45e-107 ykyB - - S - - - YkyB-like protein
MCCBHEMI_00624 1.3e-211 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
MCCBHEMI_00625 2.22e-15 - - - - - - - -
MCCBHEMI_00626 6.33e-273 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MCCBHEMI_00627 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_00628 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MCCBHEMI_00629 1.2e-167 ykwD - - J - - - protein with SCP PR1 domains
MCCBHEMI_00630 8.11e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MCCBHEMI_00631 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MCCBHEMI_00632 2.29e-252 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
MCCBHEMI_00633 1.22e-48 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_00634 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MCCBHEMI_00635 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
MCCBHEMI_00636 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_00637 1.54e-196 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
MCCBHEMI_00638 1.03e-217 ykvZ - - K - - - Transcriptional regulator
MCCBHEMI_00640 5.27e-260 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MCCBHEMI_00641 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MCCBHEMI_00642 1.26e-106 stoA - - CO - - - thiol-disulfide
MCCBHEMI_00643 3.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCCBHEMI_00644 2.59e-136 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
MCCBHEMI_00645 2.92e-38 - - - - - - - -
MCCBHEMI_00646 1.56e-34 ykvS - - S - - - protein conserved in bacteria
MCCBHEMI_00647 7.02e-58 ykvR - - S - - - Protein of unknown function (DUF3219)
MCCBHEMI_00648 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MCCBHEMI_00649 3.99e-176 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MCCBHEMI_00650 8.88e-103 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
MCCBHEMI_00651 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MCCBHEMI_00652 9.48e-231 - - - - - - - -
MCCBHEMI_00653 1.69e-219 ykvI - - S - - - membrane
MCCBHEMI_00654 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MCCBHEMI_00655 2.96e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MCCBHEMI_00656 4.64e-160 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MCCBHEMI_00657 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
MCCBHEMI_00658 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MCCBHEMI_00660 3.81e-117 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MCCBHEMI_00661 4.86e-142 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MCCBHEMI_00662 1.02e-169 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MCCBHEMI_00663 4.16e-284 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MCCBHEMI_00664 1.59e-285 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MCCBHEMI_00665 4.39e-177 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MCCBHEMI_00666 8.04e-277 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MCCBHEMI_00667 4.76e-246 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MCCBHEMI_00669 4.19e-101 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MCCBHEMI_00670 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_00671 1.59e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
MCCBHEMI_00672 1.37e-26 ykzE - - - - - - -
MCCBHEMI_00673 2.76e-144 - - - S - - - Protein of unknown function (DUF421)
MCCBHEMI_00674 1.92e-301 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
MCCBHEMI_00675 4.28e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MCCBHEMI_00676 3.65e-158 ykrK - - S - - - Domain of unknown function (DUF1836)
MCCBHEMI_00677 3.31e-35 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
MCCBHEMI_00678 2.87e-220 ykrI - - S - - - Anti-sigma factor N-terminus
MCCBHEMI_00679 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCCBHEMI_00680 5.75e-164 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MCCBHEMI_00681 1.21e-123 ykoX - - S - - - membrane-associated protein
MCCBHEMI_00682 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
MCCBHEMI_00683 4.47e-198 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MCCBHEMI_00684 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
MCCBHEMI_00685 2.57e-127 ykoP - - G - - - polysaccharide deacetylase
MCCBHEMI_00686 3.16e-104 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
MCCBHEMI_00687 3.57e-35 ykoL - - - - - - -
MCCBHEMI_00688 9.16e-23 - - - - - - - -
MCCBHEMI_00689 3.53e-69 tnrA - - K - - - transcriptional
MCCBHEMI_00690 7.93e-306 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
MCCBHEMI_00692 1.3e-302 ydhD - - M - - - Glycosyl hydrolase
MCCBHEMI_00693 3.67e-123 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MCCBHEMI_00694 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_00695 4.52e-162 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MCCBHEMI_00696 2.54e-180 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MCCBHEMI_00697 5.58e-221 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MCCBHEMI_00698 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MCCBHEMI_00699 2.14e-153 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MCCBHEMI_00700 2.94e-263 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_00701 1.11e-145 - - - K - - - Collagen triple helix repeat
MCCBHEMI_00702 2.4e-241 - - - M - - - Glycosyl transferase family 2
MCCBHEMI_00704 3.6e-71 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MCCBHEMI_00705 4.36e-89 ohrB - - O - - - Organic hydroperoxide resistance protein
MCCBHEMI_00706 3.98e-101 ohrR - - K - - - COG1846 Transcriptional regulators
MCCBHEMI_00707 9.38e-91 ohrA - - O - - - Organic hydroperoxide resistance protein
MCCBHEMI_00708 5.73e-283 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MCCBHEMI_00709 3.28e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MCCBHEMI_00710 3.09e-213 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MCCBHEMI_00711 1.22e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
MCCBHEMI_00712 9.6e-63 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
MCCBHEMI_00713 1.49e-120 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MCCBHEMI_00714 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
MCCBHEMI_00715 3.89e-184 ykgA - - E - - - Amidinotransferase
MCCBHEMI_00716 3.53e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
MCCBHEMI_00717 2.48e-226 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_00718 3.02e-199 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MCCBHEMI_00719 6.68e-243 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MCCBHEMI_00720 7.06e-220 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
MCCBHEMI_00721 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MCCBHEMI_00722 1.34e-233 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_00723 1.94e-219 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCCBHEMI_00724 7.35e-200 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCCBHEMI_00725 4.18e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
MCCBHEMI_00726 0.0 yubD - - P - - - Major Facilitator Superfamily
MCCBHEMI_00727 1.87e-269 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MCCBHEMI_00729 5e-226 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MCCBHEMI_00730 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MCCBHEMI_00731 5.01e-227 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MCCBHEMI_00732 1.05e-308 steT - - E ko:K03294 - ko00000 amino acid
MCCBHEMI_00733 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
MCCBHEMI_00734 2.36e-224 pit - - P ko:K03306 - ko00000 phosphate transporter
MCCBHEMI_00735 1.74e-168 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
MCCBHEMI_00736 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
MCCBHEMI_00737 4.2e-207 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MCCBHEMI_00738 2.62e-49 xhlB - - S - - - SPP1 phage holin
MCCBHEMI_00739 2.62e-49 xhlA - - S - - - Haemolysin XhlA
MCCBHEMI_00740 1.72e-166 xepA - - - - - - -
MCCBHEMI_00741 1.75e-35 xkdX - - - - - - -
MCCBHEMI_00743 5.56e-195 - - - - - - - -
MCCBHEMI_00744 1.48e-36 - - - - - - - -
MCCBHEMI_00745 3.37e-111 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MCCBHEMI_00746 2.53e-211 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MCCBHEMI_00747 1.65e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
MCCBHEMI_00748 3.05e-44 xkdR - - S - - - Protein of unknown function (DUF2577)
MCCBHEMI_00749 1.61e-207 xkdQ - - G - - - NLP P60 protein
MCCBHEMI_00750 8.94e-143 xkdP - - S - - - Lysin motif
MCCBHEMI_00751 1.4e-254 xkdO - - L - - - Transglycosylase SLT domain
MCCBHEMI_00752 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MCCBHEMI_00754 7.23e-99 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
MCCBHEMI_00755 5.09e-304 pre - - D - - - plasmid recombination enzyme
MCCBHEMI_00756 1.81e-108 - - - K - - - Transcriptional regulator
MCCBHEMI_00758 2.37e-251 - - - L - - - Replication protein
MCCBHEMI_00762 3.49e-21 - - - S - - - COG0433 Predicted ATPase
MCCBHEMI_00763 1.06e-20 yddB - - S - - - Conjugative transposon protein TcpC
MCCBHEMI_00767 2.45e-75 yddE - - S - - - AAA-like domain
MCCBHEMI_00769 5.92e-38 - - - M - - - Psort location CytoplasmicMembrane, score
MCCBHEMI_00772 2.48e-90 yddH - - M - - - Lysozyme-like
MCCBHEMI_00775 3.05e-35 abrB - - K ko:K06284 - ko00000,ko03000 Transition state
MCCBHEMI_00778 5.09e-156 - - - S - - - SMART Tetratricopeptide domain protein
MCCBHEMI_00782 1.92e-45 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MCCBHEMI_00786 3.27e-54 nucH 3.1.31.1 - L ko:K01174 - ko00000,ko01000 Staphylococcal nuclease homologues
MCCBHEMI_00787 1.89e-101 - - - S - - - SprT-like family
MCCBHEMI_00789 9.54e-27 - - - - - - - -
MCCBHEMI_00790 2.88e-29 - - - - - - - -
MCCBHEMI_00793 3e-160 - - - - ko:K18640 - ko00000,ko04812 -
MCCBHEMI_00796 1.27e-263 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCCBHEMI_00801 6.11e-23 - - - S ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MCCBHEMI_00802 2.65e-19 - - - V - - - VanZ like family
MCCBHEMI_00804 1.96e-17 - - - - - - - -
MCCBHEMI_00805 1.9e-65 yvrI - - K ko:K03093 - ko00000,ko03021 COG1191 DNA-directed RNA polymerase specialized sigma subunit
MCCBHEMI_00806 1.25e-13 - - - S - - - YvrJ protein family
MCCBHEMI_00808 4.64e-10 - - - - - - - -
MCCBHEMI_00816 1.91e-148 - - - L - - - Belongs to the 'phage' integrase family
MCCBHEMI_00818 4.71e-33 - - - V ko:K06877,ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
MCCBHEMI_00821 1.17e-09 - - - - - - - -
MCCBHEMI_00822 6.99e-09 - - - S ko:K09167 - ko00000 Bacterial PH domain
MCCBHEMI_00823 2.62e-51 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
MCCBHEMI_00827 1.3e-33 - - - S - - - Repressor of ComK
MCCBHEMI_00828 4.96e-26 abrB - - K ko:K06284 - ko00000,ko03000 SpoVT / AbrB like domain
MCCBHEMI_00833 8.13e-08 - - - D - - - FtsK/SpoIIIE family
MCCBHEMI_00850 2.54e-53 nucA - - M - - - Deoxyribonuclease NucA/NucB
MCCBHEMI_00851 4.63e-176 pdaB - - G - - - Polysaccharide deacetylase
MCCBHEMI_00852 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
MCCBHEMI_00853 1.95e-102 gerD - - - ko:K06294 - ko00000 -
MCCBHEMI_00854 1.95e-248 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MCCBHEMI_00855 4.3e-168 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MCCBHEMI_00856 2.28e-99 ybaK - - S - - - Protein of unknown function (DUF2521)
MCCBHEMI_00857 1.28e-178 ybaJ - - Q - - - Methyltransferase domain
MCCBHEMI_00858 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MCCBHEMI_00859 3.79e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MCCBHEMI_00860 3.42e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MCCBHEMI_00861 8.86e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCCBHEMI_00862 3.17e-186 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCCBHEMI_00863 6.9e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCCBHEMI_00864 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MCCBHEMI_00865 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCCBHEMI_00866 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MCCBHEMI_00867 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MCCBHEMI_00868 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MCCBHEMI_00869 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MCCBHEMI_00870 5.46e-181 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MCCBHEMI_00871 7.21e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MCCBHEMI_00872 1.82e-294 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MCCBHEMI_00873 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MCCBHEMI_00874 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MCCBHEMI_00875 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MCCBHEMI_00876 2.38e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MCCBHEMI_00877 1.05e-119 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MCCBHEMI_00878 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MCCBHEMI_00879 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCCBHEMI_00880 2.58e-120 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MCCBHEMI_00881 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MCCBHEMI_00882 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MCCBHEMI_00883 1.92e-51 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MCCBHEMI_00884 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MCCBHEMI_00885 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MCCBHEMI_00886 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MCCBHEMI_00887 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MCCBHEMI_00888 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MCCBHEMI_00889 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MCCBHEMI_00890 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MCCBHEMI_00891 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MCCBHEMI_00892 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MCCBHEMI_00893 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MCCBHEMI_00894 4.92e-218 ybaC - - S - - - Alpha/beta hydrolase family
MCCBHEMI_00895 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MCCBHEMI_00896 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MCCBHEMI_00897 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MCCBHEMI_00898 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MCCBHEMI_00899 9.87e-45 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
MCCBHEMI_00900 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCCBHEMI_00901 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCCBHEMI_00902 1.46e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MCCBHEMI_00903 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MCCBHEMI_00904 6.68e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MCCBHEMI_00905 5.01e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MCCBHEMI_00906 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MCCBHEMI_00907 6.9e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MCCBHEMI_00908 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MCCBHEMI_00909 4.65e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MCCBHEMI_00910 1.92e-113 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
MCCBHEMI_00911 9.69e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCCBHEMI_00912 9.32e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MCCBHEMI_00913 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MCCBHEMI_00914 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
MCCBHEMI_00915 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MCCBHEMI_00916 1.23e-110 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MCCBHEMI_00917 1.96e-157 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MCCBHEMI_00918 1.85e-245 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
MCCBHEMI_00919 3.64e-249 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MCCBHEMI_00920 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MCCBHEMI_00921 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
MCCBHEMI_00922 3.84e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MCCBHEMI_00923 8.58e-79 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
MCCBHEMI_00924 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MCCBHEMI_00925 9.8e-199 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MCCBHEMI_00926 5.27e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
MCCBHEMI_00928 5.06e-180 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MCCBHEMI_00929 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
MCCBHEMI_00930 7.99e-37 yfjT - - - - - - -
MCCBHEMI_00931 5.2e-276 yfkA - - S - - - YfkB-like domain
MCCBHEMI_00932 4.78e-185 yfkC - - M - - - Mechanosensitive ion channel
MCCBHEMI_00933 8.63e-181 yfkD - - S - - - YfkD-like protein
MCCBHEMI_00934 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
MCCBHEMI_00935 7.36e-272 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_00936 6.71e-12 - - - - - - - -
MCCBHEMI_00937 7.59e-183 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MCCBHEMI_00938 1.34e-63 yfkI - - S - - - gas vesicle protein
MCCBHEMI_00939 2.13e-106 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MCCBHEMI_00940 7.02e-40 yfkK - - S - - - Belongs to the UPF0435 family
MCCBHEMI_00941 1.74e-245 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_00942 2.01e-165 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MCCBHEMI_00943 3.96e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MCCBHEMI_00944 1.09e-230 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MCCBHEMI_00945 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MCCBHEMI_00946 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MCCBHEMI_00947 5.49e-235 yibE - - S - - - YibE/F-like protein
MCCBHEMI_00948 2.14e-158 yibF - - S - - - YibE/F-like protein
MCCBHEMI_00949 5.45e-154 frp - - C - - - nitroreductase
MCCBHEMI_00950 1.01e-162 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
MCCBHEMI_00951 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MCCBHEMI_00952 7.43e-312 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_00953 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
MCCBHEMI_00954 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
MCCBHEMI_00955 4.63e-101 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MCCBHEMI_00956 6.69e-81 ydhN1 - - S - - - Domain of unknown function (DUF1992)
MCCBHEMI_00957 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MCCBHEMI_00958 2.35e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
MCCBHEMI_00959 2.4e-313 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MCCBHEMI_00960 1.05e-174 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MCCBHEMI_00961 1.38e-65 yflH - - S - - - Protein of unknown function (DUF3243)
MCCBHEMI_00962 5.69e-26 yflI - - - - - - -
MCCBHEMI_00963 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
MCCBHEMI_00964 1.56e-152 yflK - - S - - - protein conserved in bacteria
MCCBHEMI_00965 4.43e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MCCBHEMI_00966 2.86e-268 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MCCBHEMI_00967 1.13e-181 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MCCBHEMI_00968 3.05e-282 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MCCBHEMI_00969 2.35e-218 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
MCCBHEMI_00970 4.96e-148 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MCCBHEMI_00971 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MCCBHEMI_00972 4.77e-105 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MCCBHEMI_00973 0.0 - - - M - - - cell wall anchor domain
MCCBHEMI_00974 9.64e-191 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
MCCBHEMI_00975 0.0 ywpD - - T - - - Histidine kinase
MCCBHEMI_00976 7.59e-90 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
MCCBHEMI_00999 3.12e-94 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
MCCBHEMI_01000 1.22e-159 yteA - - T - - - COG1734 DnaK suppressor protein
MCCBHEMI_01001 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MCCBHEMI_01002 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MCCBHEMI_01003 6.84e-188 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MCCBHEMI_01004 7.22e-198 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MCCBHEMI_01005 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MCCBHEMI_01006 1.79e-266 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MCCBHEMI_01007 3.88e-34 - - - S - - - Domain of Unknown Function (DUF1540)
MCCBHEMI_01008 1.01e-232 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MCCBHEMI_01009 6.36e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MCCBHEMI_01010 4.14e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MCCBHEMI_01011 4.26e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MCCBHEMI_01012 4.02e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MCCBHEMI_01013 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MCCBHEMI_01014 9.99e-98 ytkA - - S - - - YtkA-like
MCCBHEMI_01016 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MCCBHEMI_01017 1.67e-77 ytkC - - S - - - Bacteriophage holin family
MCCBHEMI_01018 5.86e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MCCBHEMI_01019 3.42e-170 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MCCBHEMI_01020 1.38e-180 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MCCBHEMI_01021 6.07e-228 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MCCBHEMI_01022 6.15e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MCCBHEMI_01023 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
MCCBHEMI_01024 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MCCBHEMI_01025 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MCCBHEMI_01026 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MCCBHEMI_01027 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MCCBHEMI_01028 3.03e-79 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MCCBHEMI_01029 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
MCCBHEMI_01030 1.03e-264 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
MCCBHEMI_01031 8.34e-168 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
MCCBHEMI_01033 1.42e-133 ytqB - - J - - - Putative rRNA methylase
MCCBHEMI_01034 3.63e-73 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
MCCBHEMI_01035 2.06e-121 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
MCCBHEMI_01036 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_01037 2.43e-148 aveG - - Q - - - Thioesterase domain
MCCBHEMI_01038 2.92e-199 - - - C - - - Nitroreductase
MCCBHEMI_01039 4.33e-27 - - - - - - - -
MCCBHEMI_01040 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
MCCBHEMI_01041 8.21e-97 xkdM - - S - - - Phage tail tube protein
MCCBHEMI_01042 2.69e-286 xkdK - - S - - - Phage tail sheath C-terminal domain
MCCBHEMI_01043 3.86e-21 - - - - - - - -
MCCBHEMI_01044 2.59e-75 xkdJ - - - - - - -
MCCBHEMI_01045 3.98e-76 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
MCCBHEMI_01046 2.25e-53 - - - S - - - Domain of unknown function (DUF3599)
MCCBHEMI_01047 1.26e-60 yqbG - - S - - - Protein of unknown function (DUF3199)
MCCBHEMI_01048 4.8e-202 xkdG - - S - - - Phage capsid family
MCCBHEMI_01049 1.71e-118 xkdF3 - - L - - - Putative phage serine protease XkdF
MCCBHEMI_01050 2.1e-303 xkdE3 - - S - - - portal protein
MCCBHEMI_01051 1.22e-265 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
MCCBHEMI_01052 2.77e-139 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
MCCBHEMI_01053 5.45e-106 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MCCBHEMI_01057 1.23e-145 xkdC - - L - - - Bacterial dnaA protein
MCCBHEMI_01058 1.42e-134 xkdB - - K - - - sequence-specific DNA binding
MCCBHEMI_01060 1.27e-72 xre - - K - - - Helix-turn-helix XRE-family like proteins
MCCBHEMI_01061 2.86e-139 xkdA - - E - - - IrrE N-terminal-like domain
MCCBHEMI_01062 6.61e-129 yjqB - - S - - - phage-related replication protein
MCCBHEMI_01063 3.19e-79 yjqA - - S - - - Bacterial PH domain
MCCBHEMI_01064 1.35e-211 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MCCBHEMI_01066 3.13e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MCCBHEMI_01067 4.66e-100 yjoA - - S - - - DinB family
MCCBHEMI_01068 7.24e-164 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
MCCBHEMI_01070 5.25e-166 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MCCBHEMI_01071 3.02e-111 - - - T - - - Transcriptional regulatory protein, C terminal
MCCBHEMI_01072 2.48e-207 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MCCBHEMI_01073 3.66e-228 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
MCCBHEMI_01074 3.21e-96 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MCCBHEMI_01075 8.37e-278 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MCCBHEMI_01076 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
MCCBHEMI_01077 2.18e-112 yjlB - - S - - - Cupin domain
MCCBHEMI_01078 7.3e-221 yjlA - - EG - - - Putative multidrug resistance efflux transporter
MCCBHEMI_01079 3.86e-160 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_01080 3.47e-150 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
MCCBHEMI_01081 4.32e-182 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MCCBHEMI_01082 1.73e-40 - - - - - - - -
MCCBHEMI_01083 2.79e-275 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MCCBHEMI_01084 1.33e-274 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MCCBHEMI_01085 5.56e-111 yjgD - - S - - - Protein of unknown function (DUF1641)
MCCBHEMI_01086 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
MCCBHEMI_01087 5.52e-120 yjgB - - S - - - Domain of unknown function (DUF4309)
MCCBHEMI_01088 2.55e-82 yjgA - - T - - - Protein of unknown function (DUF2809)
MCCBHEMI_01089 2.62e-29 yjfB - - S - - - Putative motility protein
MCCBHEMI_01090 2.77e-133 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MCCBHEMI_01091 4.16e-69 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MCCBHEMI_01092 3.81e-45 - - - - - - - -
MCCBHEMI_01093 8.28e-152 - - - S - - - Haloacid dehalogenase-like hydrolase
MCCBHEMI_01094 1.39e-177 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MCCBHEMI_01095 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MCCBHEMI_01096 2.1e-65 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_01097 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCCBHEMI_01098 7.86e-267 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
MCCBHEMI_01100 1.55e-99 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MCCBHEMI_01101 3.32e-303 yfjF - - EGP - - - Belongs to the major facilitator superfamily
MCCBHEMI_01102 8.96e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
MCCBHEMI_01103 7.13e-201 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
MCCBHEMI_01107 1.23e-32 - - - N - - - Kelch motif
MCCBHEMI_01109 4.74e-38 - - - S - - - Bacillus cereus group antimicrobial protein
MCCBHEMI_01111 2.92e-217 - - - S - - - amine dehydrogenase activity
MCCBHEMI_01114 1.91e-130 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 2-dehydropantoate 2-reductase
MCCBHEMI_01115 7.08e-99 yokH - - G - - - SMI1 / KNR4 family
MCCBHEMI_01116 4.33e-42 - - - - - - - -
MCCBHEMI_01117 2.51e-89 - - - S - - - Bacterial EndoU nuclease
MCCBHEMI_01118 1.96e-71 - - - - - - - -
MCCBHEMI_01120 1.95e-271 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MCCBHEMI_01121 8.5e-266 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MCCBHEMI_01122 1.79e-157 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
MCCBHEMI_01123 4.03e-120 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
MCCBHEMI_01124 2.11e-92 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCCBHEMI_01125 1.19e-45 - - - K - - - SpoVT / AbrB like domain
MCCBHEMI_01126 1.88e-166 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MCCBHEMI_01127 2.24e-151 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MCCBHEMI_01128 6.4e-81 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MCCBHEMI_01129 4.34e-73 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MCCBHEMI_01130 1.62e-44 - - - - - - - -
MCCBHEMI_01131 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MCCBHEMI_01132 1.05e-50 spoVIF - - S - - - Stage VI sporulation protein F
MCCBHEMI_01136 1.69e-72 yjcA - - S - - - Protein of unknown function (DUF1360)
MCCBHEMI_01137 7.64e-68 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
MCCBHEMI_01138 1.02e-36 cotW - - - ko:K06341 - ko00000 -
MCCBHEMI_01139 3.55e-98 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
MCCBHEMI_01140 1.75e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
MCCBHEMI_01141 3.35e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
MCCBHEMI_01142 1.5e-101 yjbX - - S - - - Spore coat protein
MCCBHEMI_01143 1.38e-179 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MCCBHEMI_01144 2.56e-181 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MCCBHEMI_01145 1.23e-228 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MCCBHEMI_01146 5.18e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MCCBHEMI_01147 2.16e-39 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
MCCBHEMI_01148 4.82e-254 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
MCCBHEMI_01149 4.13e-132 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
MCCBHEMI_01150 2.06e-170 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MCCBHEMI_01151 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MCCBHEMI_01152 1.1e-176 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MCCBHEMI_01153 9.83e-204 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MCCBHEMI_01154 6.92e-193 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MCCBHEMI_01155 3.67e-138 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
MCCBHEMI_01156 3.37e-79 yjbL - - S - - - Belongs to the UPF0738 family
MCCBHEMI_01157 3.44e-119 yjbK - - S - - - protein conserved in bacteria
MCCBHEMI_01158 3.83e-137 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MCCBHEMI_01159 6.79e-91 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
MCCBHEMI_01160 9.23e-215 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MCCBHEMI_01161 1.28e-26 - - - - - - - -
MCCBHEMI_01162 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MCCBHEMI_01163 4.43e-254 coiA - - S ko:K06198 - ko00000 Competence protein
MCCBHEMI_01164 2.3e-148 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MCCBHEMI_01165 1.32e-139 yjbE - - P - - - Integral membrane protein TerC family
MCCBHEMI_01166 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MCCBHEMI_01167 1.04e-130 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCCBHEMI_01168 3.17e-282 - - - S - - - Putative glycosyl hydrolase domain
MCCBHEMI_01169 4.95e-217 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_01170 1.96e-252 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_01171 1.46e-209 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCCBHEMI_01172 2.08e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCCBHEMI_01173 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MCCBHEMI_01174 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
MCCBHEMI_01175 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
MCCBHEMI_01176 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCCBHEMI_01177 8.55e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCCBHEMI_01178 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
MCCBHEMI_01179 1.1e-232 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_01180 4.64e-229 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_01181 4.1e-178 yjaZ - - O - - - Zn-dependent protease
MCCBHEMI_01182 1.24e-296 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MCCBHEMI_01183 1.26e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MCCBHEMI_01184 2.75e-20 yjzB - - - - - - -
MCCBHEMI_01185 3.74e-36 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
MCCBHEMI_01186 8.66e-209 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
MCCBHEMI_01187 1.73e-127 yjaV - - - - - - -
MCCBHEMI_01188 1.62e-171 yjaU - - I - - - carboxylic ester hydrolase activity
MCCBHEMI_01189 3.71e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
MCCBHEMI_01190 2.07e-38 yjzC - - S - - - YjzC-like protein
MCCBHEMI_01191 2.42e-218 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MCCBHEMI_01192 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
MCCBHEMI_01193 2.28e-248 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MCCBHEMI_01194 1.78e-264 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
MCCBHEMI_01195 7.23e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MCCBHEMI_01196 2.25e-284 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MCCBHEMI_01197 4.41e-247 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MCCBHEMI_01198 7.36e-116 yitZ - - G - - - Major Facilitator Superfamily
MCCBHEMI_01199 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
MCCBHEMI_01200 6.92e-94 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MCCBHEMI_01201 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
MCCBHEMI_01202 1.19e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MCCBHEMI_01203 1.57e-191 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MCCBHEMI_01204 1.49e-11 - - - - - - - -
MCCBHEMI_01205 4.3e-36 - - - S - - - Protein of unknown function (DUF3813)
MCCBHEMI_01206 3.05e-104 ipi - - S - - - Intracellular proteinase inhibitor
MCCBHEMI_01207 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MCCBHEMI_01208 1.19e-197 yitS - - S - - - protein conserved in bacteria
MCCBHEMI_01210 2.4e-296 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
MCCBHEMI_01211 7.46e-289 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MCCBHEMI_01212 6.6e-186 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
MCCBHEMI_01213 9.46e-199 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
MCCBHEMI_01214 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
MCCBHEMI_01215 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MCCBHEMI_01216 9.64e-100 - - - S - - - Acetyltransferase (GNAT) domain
MCCBHEMI_01217 2.4e-91 yisX - - S - - - Pentapeptide repeats (9 copies)
MCCBHEMI_01218 1.17e-237 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MCCBHEMI_01219 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
MCCBHEMI_01220 6.58e-103 yisT - - S - - - DinB family
MCCBHEMI_01221 3.45e-197 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MCCBHEMI_01222 6.71e-180 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MCCBHEMI_01223 7.51e-203 yisR - - K - - - Transcriptional regulator
MCCBHEMI_01224 2.92e-308 yisQ - - V - - - Mate efflux family protein
MCCBHEMI_01225 6.09e-150 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
MCCBHEMI_01226 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MCCBHEMI_01227 2.14e-114 yisN - - S - - - Protein of unknown function (DUF2777)
MCCBHEMI_01228 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MCCBHEMI_01229 9.04e-78 yisL - - S - - - UPF0344 protein
MCCBHEMI_01230 1.85e-210 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MCCBHEMI_01231 2.45e-13 yisI - - S - - - Spo0E like sporulation regulatory protein
MCCBHEMI_01232 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
MCCBHEMI_01233 1.01e-44 gerPB - - S ko:K06300 - ko00000 cell differentiation
MCCBHEMI_01234 3.28e-104 gerPC - - S ko:K06301 - ko00000 Spore germination protein
MCCBHEMI_01235 1.44e-31 gerPD - - S ko:K06302 - ko00000 Spore germination protein
MCCBHEMI_01236 1.43e-78 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
MCCBHEMI_01237 5.49e-42 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
MCCBHEMI_01238 4.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
MCCBHEMI_01239 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
MCCBHEMI_01240 4.51e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MCCBHEMI_01241 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MCCBHEMI_01242 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
MCCBHEMI_01243 3.08e-152 ydfS - - S - - - Protein of unknown function (DUF421)
MCCBHEMI_01244 3.47e-108 yhjR - - S - - - Rubrerythrin
MCCBHEMI_01245 3.05e-139 - - - K - - - QacR-like protein, C-terminal region
MCCBHEMI_01246 2.7e-261 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_01247 4.99e-255 yhjN - - S ko:K07120 - ko00000 membrane
MCCBHEMI_01248 5.95e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
MCCBHEMI_01249 0.0 yhjG - - CH - - - FAD binding domain
MCCBHEMI_01250 1.3e-116 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MCCBHEMI_01251 8.02e-136 yhjE - - S - - - SNARE associated Golgi protein
MCCBHEMI_01252 1.14e-76 yhjD - - - - - - -
MCCBHEMI_01253 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
MCCBHEMI_01254 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MCCBHEMI_01255 1.31e-63 - - - S - - - Belongs to the UPF0145 family
MCCBHEMI_01256 7.11e-57 yhjA - - S - - - Excalibur calcium-binding domain
MCCBHEMI_01257 3.92e-157 yrpD - - S - - - Domain of unknown function, YrpD
MCCBHEMI_01258 1.28e-213 - - - S - - - Acetyltransferase, GNAT family
MCCBHEMI_01259 4.21e-74 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MCCBHEMI_01260 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
MCCBHEMI_01261 5.49e-42 yhzC - - S - - - IDEAL
MCCBHEMI_01262 2.73e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCCBHEMI_01263 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
MCCBHEMI_01264 2.08e-272 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
MCCBHEMI_01265 8.1e-111 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MCCBHEMI_01266 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MCCBHEMI_01267 3.61e-246 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MCCBHEMI_01268 3.35e-131 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
MCCBHEMI_01269 5.1e-163 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MCCBHEMI_01270 1.24e-258 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MCCBHEMI_01271 4.64e-294 yhfN - - O - - - Peptidase M48
MCCBHEMI_01272 6.55e-84 yhfM - - - - - - -
MCCBHEMI_01273 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MCCBHEMI_01274 3.92e-137 yhfK - - GM - - - NmrA-like family
MCCBHEMI_01275 1.85e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MCCBHEMI_01276 3.97e-172 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MCCBHEMI_01277 1.53e-285 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCCBHEMI_01278 1.66e-247 yhfE - - G - - - peptidase M42
MCCBHEMI_01280 4.11e-226 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MCCBHEMI_01282 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
MCCBHEMI_01283 8.55e-129 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_01284 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MCCBHEMI_01285 8.34e-228 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MCCBHEMI_01286 1.31e-252 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MCCBHEMI_01287 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MCCBHEMI_01288 7.3e-116 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MCCBHEMI_01289 9.54e-303 yhfA - - C - - - membrane
MCCBHEMI_01290 3.39e-274 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MCCBHEMI_01291 1.26e-154 ecsC - - S - - - EcsC protein family
MCCBHEMI_01292 1.19e-276 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MCCBHEMI_01293 6.09e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
MCCBHEMI_01294 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MCCBHEMI_01295 1.05e-252 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MCCBHEMI_01296 5.56e-98 trpP - - S - - - Tryptophan transporter TrpP
MCCBHEMI_01297 2.55e-24 - - - - - - - -
MCCBHEMI_01298 1.58e-53 yhaH - - S - - - YtxH-like protein
MCCBHEMI_01299 4.54e-144 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
MCCBHEMI_01300 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
MCCBHEMI_01301 8.73e-122 yhaK - - S - - - Putative zincin peptidase
MCCBHEMI_01302 7.87e-183 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MCCBHEMI_01303 8.23e-43 yhaL - - S - - - Sporulation protein YhaL
MCCBHEMI_01304 2.38e-224 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
MCCBHEMI_01305 0.0 yhaN - - L - - - AAA domain
MCCBHEMI_01306 1.14e-294 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
MCCBHEMI_01307 1.32e-274 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
MCCBHEMI_01308 1.21e-209 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_01309 9.58e-18 - - - S - - - YhzD-like protein
MCCBHEMI_01310 2.18e-170 yhaR - - I - - - enoyl-CoA hydratase
MCCBHEMI_01312 1.53e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MCCBHEMI_01313 2.13e-261 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
MCCBHEMI_01314 1.48e-311 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
MCCBHEMI_01315 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
MCCBHEMI_01316 2.49e-197 yhaX - - S - - - haloacid dehalogenase-like hydrolase
MCCBHEMI_01317 2.72e-69 yheA - - S - - - Belongs to the UPF0342 family
MCCBHEMI_01318 1.09e-254 yheB - - S - - - Belongs to the UPF0754 family
MCCBHEMI_01319 2.7e-257 yheC - - HJ - - - YheC/D like ATP-grasp
MCCBHEMI_01320 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
MCCBHEMI_01321 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
MCCBHEMI_01322 1.91e-38 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
MCCBHEMI_01324 2.88e-128 yheG - - GM - - - NAD(P)H-binding
MCCBHEMI_01325 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MCCBHEMI_01326 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MCCBHEMI_01327 2.39e-108 - - - T - - - universal stress protein
MCCBHEMI_01328 1.66e-118 ymcC - - S - - - Membrane
MCCBHEMI_01329 2.53e-107 pksA - - K - - - Transcriptional regulator
MCCBHEMI_01330 1.82e-192 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MCCBHEMI_01331 3.96e-191 nodB1 - - G - - - deacetylase
MCCBHEMI_01332 7.42e-174 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MCCBHEMI_01333 5.63e-254 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
MCCBHEMI_01334 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
MCCBHEMI_01335 1.6e-159 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MCCBHEMI_01336 4.22e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCCBHEMI_01337 1.68e-69 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCCBHEMI_01338 6.38e-313 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
MCCBHEMI_01339 1.22e-288 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MCCBHEMI_01340 6.89e-278 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MCCBHEMI_01341 2.3e-91 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
MCCBHEMI_01342 2.66e-305 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MCCBHEMI_01343 6.98e-137 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MCCBHEMI_01344 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MCCBHEMI_01345 2.88e-249 yhdL - - S - - - Sigma factor regulator N-terminal
MCCBHEMI_01346 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
MCCBHEMI_01347 1.33e-263 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MCCBHEMI_01348 1.1e-311 yhdG - - E ko:K03294 - ko00000 amino acid
MCCBHEMI_01349 4.17e-201 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCCBHEMI_01350 4.61e-252 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MCCBHEMI_01351 4.86e-201 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_01352 2.28e-166 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MCCBHEMI_01353 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MCCBHEMI_01354 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
MCCBHEMI_01355 3.85e-312 ygxB - - M - - - Conserved TM helix
MCCBHEMI_01356 1.49e-93 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
MCCBHEMI_01357 4.61e-280 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MCCBHEMI_01358 2.33e-68 yhdC - - S - - - Protein of unknown function (DUF3889)
MCCBHEMI_01359 1.16e-51 yhdB - - S - - - YhdB-like protein
MCCBHEMI_01360 5.83e-108 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
MCCBHEMI_01361 1.61e-138 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCCBHEMI_01362 6.42e-122 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_01363 8.5e-58 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_01364 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
MCCBHEMI_01365 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MCCBHEMI_01366 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MCCBHEMI_01367 2.6e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MCCBHEMI_01368 3.35e-131 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MCCBHEMI_01369 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MCCBHEMI_01370 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MCCBHEMI_01371 1.33e-158 yhcW - - S ko:K07025 - ko00000 hydrolase
MCCBHEMI_01372 5.88e-89 yhcV - - S - - - COG0517 FOG CBS domain
MCCBHEMI_01373 6.81e-86 yhcU - - S - - - Family of unknown function (DUF5365)
MCCBHEMI_01374 1.84e-206 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MCCBHEMI_01375 5.71e-131 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
MCCBHEMI_01376 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MCCBHEMI_01377 4.1e-147 yhcQ - - M - - - Spore coat protein
MCCBHEMI_01378 8.06e-199 yhcP - - - - - - -
MCCBHEMI_01379 2.12e-117 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MCCBHEMI_01385 1.27e-186 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MCCBHEMI_01386 4.34e-198 - - - K - - - Helix-turn-helix XRE-family like proteins
MCCBHEMI_01387 8.62e-156 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
MCCBHEMI_01388 5.49e-102 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
MCCBHEMI_01389 9.24e-181 bltR - - K - - - helix_turn_helix, mercury resistance
MCCBHEMI_01390 7.5e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MCCBHEMI_01391 3.85e-137 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MCCBHEMI_01392 1.74e-133 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
MCCBHEMI_01393 4.18e-212 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Isocitrate/isopropylmalate dehydrogenase
MCCBHEMI_01394 1.07e-143 ydhC - - K - - - FCD
MCCBHEMI_01395 5.03e-277 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MCCBHEMI_01397 3.98e-311 pbpE - - V - - - Beta-lactamase
MCCBHEMI_01399 2.9e-126 ydhK - - M - - - Protein of unknown function (DUF1541)
MCCBHEMI_01400 2.91e-243 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
MCCBHEMI_01401 2.69e-167 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
MCCBHEMI_01402 2.75e-146 - - - K ko:K05799 - ko00000,ko03000 FCD
MCCBHEMI_01403 6.98e-267 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
MCCBHEMI_01404 2.88e-63 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
MCCBHEMI_01405 1.76e-64 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MCCBHEMI_01406 1.07e-128 yvdT_1 - - K - - - Transcriptional regulator
MCCBHEMI_01407 0.0 ybeC - - E - - - amino acid
MCCBHEMI_01408 4.74e-209 ydhU - - P ko:K07217 - ko00000 Catalase
MCCBHEMI_01409 7.76e-108 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
MCCBHEMI_01410 3.96e-228 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
MCCBHEMI_01411 4.86e-313 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MCCBHEMI_01414 1.5e-40 csfB - - S - - - Inhibitor of sigma-G Gin
MCCBHEMI_01415 9.02e-131 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MCCBHEMI_01416 6.32e-226 yaaN - - P - - - Belongs to the TelA family
MCCBHEMI_01417 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
MCCBHEMI_01418 4.13e-140 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MCCBHEMI_01419 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
MCCBHEMI_01420 1.36e-90 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
MCCBHEMI_01421 8.67e-230 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MCCBHEMI_01422 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
MCCBHEMI_01423 2.53e-55 yabA - - L - - - Involved in initiation control of chromosome replication
MCCBHEMI_01424 9.02e-175 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
MCCBHEMI_01425 8.14e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
MCCBHEMI_01426 5.68e-201 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MCCBHEMI_01427 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
MCCBHEMI_01428 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MCCBHEMI_01429 1.19e-181 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
MCCBHEMI_01430 2.28e-284 yabE - - T - - - protein conserved in bacteria
MCCBHEMI_01431 3.1e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MCCBHEMI_01432 6.91e-202 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MCCBHEMI_01433 1.46e-186 yabG - - S ko:K06436 - ko00000 peptidase
MCCBHEMI_01434 5.32e-53 veg - - S - - - protein conserved in bacteria
MCCBHEMI_01435 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
MCCBHEMI_01436 2.25e-205 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MCCBHEMI_01437 5.43e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MCCBHEMI_01438 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
MCCBHEMI_01439 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MCCBHEMI_01440 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MCCBHEMI_01441 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MCCBHEMI_01442 1.4e-133 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MCCBHEMI_01443 2.89e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MCCBHEMI_01444 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
MCCBHEMI_01445 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MCCBHEMI_01446 1.09e-116 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
MCCBHEMI_01447 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCCBHEMI_01448 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MCCBHEMI_01449 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MCCBHEMI_01450 5.47e-66 yabP - - S - - - Sporulation protein YabP
MCCBHEMI_01451 6.24e-130 yabQ - - S - - - spore cortex biosynthesis protein
MCCBHEMI_01452 2.42e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MCCBHEMI_01453 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MCCBHEMI_01456 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
MCCBHEMI_01457 8.92e-165 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MCCBHEMI_01458 2.78e-228 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
MCCBHEMI_01459 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MCCBHEMI_01460 4.29e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
MCCBHEMI_01461 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MCCBHEMI_01462 6.69e-177 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MCCBHEMI_01463 7.52e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MCCBHEMI_01464 2.45e-192 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
MCCBHEMI_01465 1.79e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MCCBHEMI_01466 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MCCBHEMI_01467 6e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
MCCBHEMI_01468 3.7e-190 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
MCCBHEMI_01469 2.41e-198 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MCCBHEMI_01470 1.88e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MCCBHEMI_01471 4.38e-113 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MCCBHEMI_01472 9.99e-39 yazB - - K - - - transcriptional
MCCBHEMI_01473 8.33e-230 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MCCBHEMI_01474 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MCCBHEMI_01475 1.03e-73 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MCCBHEMI_01483 4.1e-74 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MCCBHEMI_01484 1.78e-21 - - - - - - - -
MCCBHEMI_01485 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
MCCBHEMI_01486 2.16e-136 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
MCCBHEMI_01487 7.66e-179 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCCBHEMI_01488 5.84e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MCCBHEMI_01489 3.83e-68 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
MCCBHEMI_01490 1.71e-239 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
MCCBHEMI_01491 5.79e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MCCBHEMI_01492 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
MCCBHEMI_01493 9.89e-176 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
MCCBHEMI_01494 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MCCBHEMI_01495 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MCCBHEMI_01496 7.09e-273 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MCCBHEMI_01497 1.18e-230 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
MCCBHEMI_01498 4.08e-71 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MCCBHEMI_01499 6.7e-135 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
MCCBHEMI_01500 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
MCCBHEMI_01501 4.52e-91 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MCCBHEMI_01502 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MCCBHEMI_01503 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MCCBHEMI_01504 7.23e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MCCBHEMI_01505 2.25e-74 ydbP - - CO - - - Thioredoxin
MCCBHEMI_01506 5.73e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MCCBHEMI_01507 6.11e-15 - - - S - - - Fur-regulated basic protein A
MCCBHEMI_01508 2.36e-17 - - - S - - - Fur-regulated basic protein B
MCCBHEMI_01509 5.52e-256 ydbM - - I - - - acyl-CoA dehydrogenase
MCCBHEMI_01510 9.32e-70 ydbL - - - - - - -
MCCBHEMI_01511 5.5e-164 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MCCBHEMI_01512 3.77e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_01513 1.85e-225 ydbI - - S - - - AI-2E family transporter
MCCBHEMI_01514 3.75e-285 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCCBHEMI_01515 4.6e-147 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MCCBHEMI_01516 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MCCBHEMI_01517 7.93e-248 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MCCBHEMI_01518 2.61e-196 ydbD - - P ko:K07217 - ko00000 Catalase
MCCBHEMI_01519 6.59e-76 ydbC - - S - - - Domain of unknown function (DUF4937
MCCBHEMI_01520 1.28e-82 ydbB - - G - - - Cupin domain
MCCBHEMI_01521 1.5e-07 gsiB - - S ko:K06884 - ko00000 general stress protein
MCCBHEMI_01522 4.54e-174 ydbA - - P - - - EcsC protein family
MCCBHEMI_01523 2.76e-69 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MCCBHEMI_01524 6.73e-97 yvaD - - S - - - Family of unknown function (DUF5360)
MCCBHEMI_01525 1.95e-45 ydaT - - - - - - -
MCCBHEMI_01527 1.47e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MCCBHEMI_01528 1.06e-53 - - - - - - - -
MCCBHEMI_01530 2.91e-79 - - - K - - - acetyltransferase
MCCBHEMI_01531 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MCCBHEMI_01532 7.84e-91 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MCCBHEMI_01533 0.0 ydaO - - E - - - amino acid
MCCBHEMI_01534 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
MCCBHEMI_01535 1.77e-300 ydaM - - M - - - Glycosyl transferase family group 2
MCCBHEMI_01536 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
MCCBHEMI_01537 5.77e-184 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
MCCBHEMI_01538 9.47e-241 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MCCBHEMI_01539 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MCCBHEMI_01540 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MCCBHEMI_01541 8.95e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
MCCBHEMI_01542 9.89e-174 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MCCBHEMI_01543 5.05e-99 ydaG - - S - - - general stress protein
MCCBHEMI_01544 1.9e-138 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MCCBHEMI_01545 7.59e-123 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
MCCBHEMI_01546 2.36e-199 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCCBHEMI_01547 0.0 ydaB - - IQ - - - acyl-CoA ligase
MCCBHEMI_01548 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
MCCBHEMI_01549 6.23e-213 ycsN - - S - - - Oxidoreductase
MCCBHEMI_01550 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
MCCBHEMI_01551 2.34e-72 yczJ - - S - - - biosynthesis
MCCBHEMI_01553 4.64e-142 ycsK - - E - - - anatomical structure formation involved in morphogenesis
MCCBHEMI_01554 1.22e-162 kipR - - K - - - Transcriptional regulator
MCCBHEMI_01555 3.48e-224 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
MCCBHEMI_01556 1.75e-170 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
MCCBHEMI_01557 1.96e-182 ycsI - - S - - - Belongs to the D-glutamate cyclase family
MCCBHEMI_01558 3.46e-267 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
MCCBHEMI_01559 2.87e-170 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
MCCBHEMI_01560 2.59e-175 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MCCBHEMI_01562 4.09e-78 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MCCBHEMI_01563 6.86e-256 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
MCCBHEMI_01564 1.96e-93 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MCCBHEMI_01565 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
MCCBHEMI_01566 6.5e-71 - - - - - - - -
MCCBHEMI_01567 1.43e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MCCBHEMI_01568 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
MCCBHEMI_01569 1.48e-124 ycnI - - S - - - protein conserved in bacteria
MCCBHEMI_01570 7.4e-181 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCCBHEMI_01571 1.12e-188 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
MCCBHEMI_01572 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MCCBHEMI_01573 1.5e-278 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MCCBHEMI_01574 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MCCBHEMI_01575 1.08e-67 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MCCBHEMI_01576 2.79e-59 ycnE - - S - - - Monooxygenase
MCCBHEMI_01577 2.68e-172 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
MCCBHEMI_01578 4.78e-192 ycnC - - K - - - Transcriptional regulator
MCCBHEMI_01579 2.3e-310 ycnB - - EGP - - - the major facilitator superfamily
MCCBHEMI_01580 2.89e-221 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
MCCBHEMI_01581 4.44e-173 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_01582 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCCBHEMI_01583 1.06e-208 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCCBHEMI_01584 3.57e-315 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MCCBHEMI_01587 9.92e-96 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MCCBHEMI_01588 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
MCCBHEMI_01589 2.5e-162 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCCBHEMI_01590 4.84e-300 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
MCCBHEMI_01591 1.23e-153 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MCCBHEMI_01592 4.93e-303 yxeQ - - S - - - MmgE/PrpD family
MCCBHEMI_01593 2.11e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
MCCBHEMI_01594 1.87e-168 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_01595 8.59e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MCCBHEMI_01596 2.03e-179 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MCCBHEMI_01597 7.07e-117 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCCBHEMI_01598 1.7e-315 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCCBHEMI_01599 2.82e-243 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
MCCBHEMI_01600 5.6e-291 gerKC - - S ko:K06297 - ko00000 spore germination
MCCBHEMI_01601 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
MCCBHEMI_01603 0.0 yclG - - M - - - Pectate lyase superfamily protein
MCCBHEMI_01604 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
MCCBHEMI_01605 8.93e-96 yclD - - - - - - -
MCCBHEMI_01606 6.46e-49 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
MCCBHEMI_01607 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MCCBHEMI_01608 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MCCBHEMI_01609 3.54e-198 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
MCCBHEMI_01610 3.82e-185 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MCCBHEMI_01611 5.85e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MCCBHEMI_01612 9.29e-168 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MCCBHEMI_01613 1.12e-137 yczE - - S ko:K07149 - ko00000 membrane
MCCBHEMI_01614 2.39e-154 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MCCBHEMI_01615 5.89e-314 - - - E - - - Aminotransferase class I and II
MCCBHEMI_01616 8.06e-176 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
MCCBHEMI_01617 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
MCCBHEMI_01618 1.81e-265 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCCBHEMI_01619 1.41e-225 yaaC - - S - - - YaaC-like Protein
MCCBHEMI_01620 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MCCBHEMI_01621 2.81e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MCCBHEMI_01622 7.47e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MCCBHEMI_01623 2.35e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MCCBHEMI_01624 2.51e-282 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MCCBHEMI_01625 2.36e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MCCBHEMI_01627 6.92e-155 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
MCCBHEMI_01628 3.32e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
MCCBHEMI_01629 3.44e-269 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
MCCBHEMI_01630 1.33e-124 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
MCCBHEMI_01631 2.78e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MCCBHEMI_01632 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MCCBHEMI_01633 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MCCBHEMI_01634 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MCCBHEMI_01635 2.2e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
MCCBHEMI_01636 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
MCCBHEMI_01638 1.66e-07 - - - - - - - -
MCCBHEMI_01639 1.9e-10 - - - K - - - Transcriptional regulator
MCCBHEMI_01640 7.91e-10 lexA 3.4.21.88 - KT ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MCCBHEMI_01643 0.00014 - - - K - - - XRE family transcriptional regulator
MCCBHEMI_01652 1.25e-77 - - - - - - - -
MCCBHEMI_01656 1.07e-57 - - - S - - - transposition, DNA-mediated
MCCBHEMI_01657 1.53e-148 - - - S - - - HTH-like domain
MCCBHEMI_01660 1e-12 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_01661 3.57e-20 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_01662 1.09e-199 - - - S - - - Domain of unknown function (DUF5068)
MCCBHEMI_01663 3.19e-42 - - - - - - - -
MCCBHEMI_01664 1.38e-56 - - - L - - - Initiator Replication protein
MCCBHEMI_01665 3.88e-06 - - - S - - - SEC-C motif
MCCBHEMI_01672 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
MCCBHEMI_01673 3.26e-72 - - - L - - - transposase activity
MCCBHEMI_01677 8.35e-11 - - - M - - - NlpC P60 family protein
MCCBHEMI_01680 5.86e-29 pilT - - NU ko:K02669 - ko00000,ko02035,ko02044 PFAM Type II secretion system protein E
MCCBHEMI_01691 3.07e-27 - - - K - - - Transcriptional regulator
MCCBHEMI_01694 2.15e-41 - - - L - - - DnaD domain protein
MCCBHEMI_01696 0.000533 - - - K ko:K07075,ko:K15773 - ko00000,ko02048,ko03000 sequence-specific DNA binding
MCCBHEMI_01697 1.47e-67 ypuA - - S - - - Protein of unknown function (DUF1002)
MCCBHEMI_01708 1.1e-08 - - - - - - - -
MCCBHEMI_01709 4.66e-68 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
MCCBHEMI_01710 1.45e-175 - - - M - - - Psort location Cellwall, score
MCCBHEMI_01714 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCCBHEMI_01715 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCCBHEMI_01716 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
MCCBHEMI_01717 1.25e-261 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MCCBHEMI_01718 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MCCBHEMI_01719 2.83e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MCCBHEMI_01720 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MCCBHEMI_01721 1.84e-67 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MCCBHEMI_01722 6.08e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MCCBHEMI_01723 2.88e-136 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
MCCBHEMI_01724 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MCCBHEMI_01725 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MCCBHEMI_01726 2.56e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MCCBHEMI_01727 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MCCBHEMI_01728 2.49e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
MCCBHEMI_01729 6.79e-188 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MCCBHEMI_01730 5.5e-141 yyaC - - S - - - Sporulation protein YyaC
MCCBHEMI_01731 7.76e-62 yhhY - - K - - - FR47-like protein
MCCBHEMI_01732 1.9e-215 yyaD - - S - - - Membrane
MCCBHEMI_01733 1.82e-45 yyzM - - S - - - protein conserved in bacteria
MCCBHEMI_01734 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MCCBHEMI_01735 6.32e-253 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MCCBHEMI_01736 3.39e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MCCBHEMI_01737 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MCCBHEMI_01738 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MCCBHEMI_01739 1.3e-125 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
MCCBHEMI_01740 1.39e-113 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MCCBHEMI_01741 8.34e-178 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MCCBHEMI_01742 7.31e-218 ccpB - - K - - - Transcriptional regulator
MCCBHEMI_01743 3.3e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCCBHEMI_01744 3.95e-228 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
MCCBHEMI_01745 1.17e-193 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
MCCBHEMI_01746 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MCCBHEMI_01747 5.94e-31 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
MCCBHEMI_01748 2.57e-12 - - - KLT - - - serine threonine protein kinase
MCCBHEMI_01751 4.38e-50 - - - E - - - Pfam:DUF955
MCCBHEMI_01752 1.07e-41 - - - K - - - Transcriptional
MCCBHEMI_01753 6.63e-14 - - - - - - - -
MCCBHEMI_01754 2.53e-33 - - - - - - - -
MCCBHEMI_01756 9.29e-51 - - - S - - - Bacterial protein of unknown function (DUF961)
MCCBHEMI_01757 5.35e-287 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
MCCBHEMI_01758 1.3e-204 nicK - - L ko:K07467 - ko00000 Replication initiation factor
MCCBHEMI_01759 8.93e-23 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
MCCBHEMI_01764 1.21e-163 yddB - - S - - - Conjugative transposon protein TcpC
MCCBHEMI_01765 2.72e-33 yddC - - - - - - -
MCCBHEMI_01766 3.73e-97 yddD - - S - - - TcpE family
MCCBHEMI_01767 0.0 yddE - - S - - - AAA-like domain
MCCBHEMI_01768 2.17e-45 - - - S - - - Domain of unknown function (DUF1874)
MCCBHEMI_01769 1.68e-258 yddG - - S - - - maturation of SSU-rRNA
MCCBHEMI_01770 6.21e-202 yddH - - M - - - Lysozyme-like
MCCBHEMI_01771 3.82e-73 yddI - - - - - - -
MCCBHEMI_01772 1.45e-55 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
MCCBHEMI_01775 1.07e-157 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MCCBHEMI_01792 0.0 - - - C - - - Na+/H+ antiporter family
MCCBHEMI_01793 5.85e-159 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MCCBHEMI_01794 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MCCBHEMI_01795 1.82e-312 ygaK - - C - - - Berberine and berberine like
MCCBHEMI_01797 9.3e-290 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
MCCBHEMI_01798 2.33e-185 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MCCBHEMI_01799 2.17e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCCBHEMI_01800 5.45e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_01801 5.17e-165 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_01802 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MCCBHEMI_01803 3.97e-226 - - - S ko:K07045 - ko00000 Amidohydrolase
MCCBHEMI_01804 2.67e-172 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MCCBHEMI_01805 4.22e-221 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
MCCBHEMI_01806 9.24e-183 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MCCBHEMI_01807 2.88e-271 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
MCCBHEMI_01809 1.62e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCCBHEMI_01810 1.62e-100 ygaO - - - - - - -
MCCBHEMI_01811 1.34e-31 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_01813 3.16e-137 yhzB - - S - - - B3/4 domain
MCCBHEMI_01814 9.07e-282 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MCCBHEMI_01815 2.06e-216 yhbB - - S - - - Putative amidase domain
MCCBHEMI_01816 2.31e-110 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MCCBHEMI_01817 1.42e-133 yhbD - - K - - - Protein of unknown function (DUF4004)
MCCBHEMI_01818 1.44e-75 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MCCBHEMI_01819 3.22e-86 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MCCBHEMI_01820 1.23e-07 - - - - - - - -
MCCBHEMI_01821 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
MCCBHEMI_01822 2.48e-275 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
MCCBHEMI_01823 5.43e-94 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
MCCBHEMI_01824 2.98e-130 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
MCCBHEMI_01825 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
MCCBHEMI_01826 2.61e-128 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MCCBHEMI_01827 1.77e-66 yhcC - - - - - - -
MCCBHEMI_01828 7.54e-65 - - - - - - - -
MCCBHEMI_01829 7.22e-76 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_01830 5.37e-148 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_01831 2.16e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_01832 5.36e-201 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MCCBHEMI_01833 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MCCBHEMI_01834 6.98e-164 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MCCBHEMI_01835 1.31e-228 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
MCCBHEMI_01836 1.44e-290 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCCBHEMI_01837 6.07e-185 yxaL - - S - - - PQQ-like domain
MCCBHEMI_01838 7.08e-76 - - - S - - - Family of unknown function (DUF5391)
MCCBHEMI_01839 2.01e-66 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MCCBHEMI_01840 2.86e-251 - - - EGP - - - Major Facilitator Superfamily
MCCBHEMI_01841 3.15e-87 yxaI - - S - - - membrane protein domain
MCCBHEMI_01842 6.56e-154 - - - E - - - Ring-cleavage extradiol dioxygenase
MCCBHEMI_01843 1.55e-134 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
MCCBHEMI_01844 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
MCCBHEMI_01845 2.82e-231 mrjp - - G - - - Major royal jelly protein
MCCBHEMI_01846 6.23e-302 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MCCBHEMI_01847 7.86e-201 - - - K - - - helix_turn_helix, Deoxyribose operon repressor
MCCBHEMI_01848 1.21e-94 - - - K - - - Integron-associated effector binding protein
MCCBHEMI_01849 4.44e-98 yjhE - - S - - - Phage tail protein
MCCBHEMI_01850 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
MCCBHEMI_01851 4.23e-99 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MCCBHEMI_01852 1.42e-183 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MCCBHEMI_01853 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MCCBHEMI_01854 2.96e-104 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
MCCBHEMI_01855 2.3e-214 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MCCBHEMI_01856 2.26e-209 - - - S - - - Fusaric acid resistance protein-like
MCCBHEMI_01857 1.97e-19 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
MCCBHEMI_01860 2.01e-202 rarA - - L ko:K07478 - ko00000 atpase related to the helicase subunit of the holliday junction resolvase
MCCBHEMI_01861 2.4e-48 - - - - - - - -
MCCBHEMI_01862 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MCCBHEMI_01865 5.96e-264 yycP - - - - - - -
MCCBHEMI_01866 6.27e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MCCBHEMI_01867 5.64e-229 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MCCBHEMI_01868 2.13e-106 yycN - - K - - - Acetyltransferase
MCCBHEMI_01870 4.14e-256 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
MCCBHEMI_01871 7.27e-210 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MCCBHEMI_01872 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MCCBHEMI_01873 1.75e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
MCCBHEMI_01874 2.51e-75 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MCCBHEMI_01875 3.82e-57 sdpR - - K - - - transcriptional
MCCBHEMI_01876 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MCCBHEMI_01877 8.45e-185 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
MCCBHEMI_01878 0.0 - - - S - - - ABC transporter
MCCBHEMI_01879 4.08e-255 - - - S - - - Major Facilitator Superfamily
MCCBHEMI_01880 2.37e-306 - - - - - - - -
MCCBHEMI_01881 6.19e-230 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
MCCBHEMI_01882 3.64e-308 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MCCBHEMI_01883 1.36e-118 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
MCCBHEMI_01884 7.86e-85 - - - S - - - Peptidase propeptide and YPEB domain
MCCBHEMI_01885 1.17e-271 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MCCBHEMI_01886 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MCCBHEMI_01887 3.14e-191 yycI - - S - - - protein conserved in bacteria
MCCBHEMI_01888 0.0 yycH - - S - - - protein conserved in bacteria
MCCBHEMI_01889 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_01890 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCCBHEMI_01895 4.45e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MCCBHEMI_01896 3.71e-93 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCCBHEMI_01897 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MCCBHEMI_01898 9e-38 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MCCBHEMI_01900 4.22e-24 yycC - - K - - - YycC-like protein
MCCBHEMI_01901 2.33e-272 - - - M - - - Glycosyltransferase Family 4
MCCBHEMI_01902 1.93e-244 - - - S - - - Ecdysteroid kinase
MCCBHEMI_01903 4.08e-291 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
MCCBHEMI_01904 1.37e-279 - - - M - - - Glycosyltransferase Family 4
MCCBHEMI_01905 1.7e-154 - - - S - - - GlcNAc-PI de-N-acetylase
MCCBHEMI_01906 1.92e-106 - - - KLT - - - COG0515 Serine threonine protein kinase
MCCBHEMI_01907 2.25e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MCCBHEMI_01908 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MCCBHEMI_01909 2.59e-190 yybS - - S - - - membrane
MCCBHEMI_01911 3.36e-105 cotF - - M ko:K06329 - ko00000 Spore coat protein
MCCBHEMI_01912 7.09e-79 yybR - - K - - - Transcriptional regulator
MCCBHEMI_01913 4.01e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
MCCBHEMI_01914 7.65e-193 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MCCBHEMI_01915 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
MCCBHEMI_01916 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MCCBHEMI_01917 3.37e-143 - - - K - - - FCD domain
MCCBHEMI_01919 3.75e-53 - - - CP - - - Membrane
MCCBHEMI_01921 2.63e-29 - - - S - - - Domain of unknown function (DUF4177)
MCCBHEMI_01922 2.66e-31 - - - - - - - -
MCCBHEMI_01923 7.04e-24 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
MCCBHEMI_01925 2.54e-70 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MCCBHEMI_01926 1.56e-144 ydgI - - C - - - nitroreductase
MCCBHEMI_01927 1.04e-84 - - - K - - - Winged helix DNA-binding domain
MCCBHEMI_01928 9.98e-190 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MCCBHEMI_01929 1.78e-97 yybA - - K - - - transcriptional
MCCBHEMI_01930 2e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
MCCBHEMI_01931 4.37e-54 - - - - - - - -
MCCBHEMI_01932 5.31e-90 ynaF - - - - - - -
MCCBHEMI_01933 4.09e-30 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MCCBHEMI_01934 1.38e-37 - - - L - - - Recombinase
MCCBHEMI_01935 3.55e-118 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MCCBHEMI_01936 2.39e-274 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
MCCBHEMI_01937 1.48e-104 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
MCCBHEMI_01938 8.21e-102 yuaE - - S - - - DinB superfamily
MCCBHEMI_01939 2.01e-133 - - - S - - - MOSC domain
MCCBHEMI_01940 5.58e-287 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MCCBHEMI_01941 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MCCBHEMI_01942 1.13e-117 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
MCCBHEMI_01943 4.6e-119 yuaB - - - - - - -
MCCBHEMI_01944 8.36e-154 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MCCBHEMI_01945 9.64e-187 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MCCBHEMI_01946 2.65e-269 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MCCBHEMI_01947 5.65e-143 - - - G - - - Cupin
MCCBHEMI_01948 4.37e-59 yjcN - - - - - - -
MCCBHEMI_01951 2.15e-177 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
MCCBHEMI_01952 7.36e-20 - - - - - - - -
MCCBHEMI_01954 9.58e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MCCBHEMI_01955 2.73e-248 yubA - - S - - - transporter activity
MCCBHEMI_01956 3.27e-229 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MCCBHEMI_01957 4.02e-126 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MCCBHEMI_01958 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MCCBHEMI_01959 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MCCBHEMI_01960 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MCCBHEMI_01961 5.19e-284 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MCCBHEMI_01962 1.68e-174 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MCCBHEMI_01963 1.82e-52 - - - - - - - -
MCCBHEMI_01964 4.87e-238 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MCCBHEMI_01965 2.4e-97 yugU - - S - - - Uncharacterised protein family UPF0047
MCCBHEMI_01966 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MCCBHEMI_01967 1.82e-293 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MCCBHEMI_01968 1.95e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
MCCBHEMI_01969 3.56e-22 - - - - - - - -
MCCBHEMI_01970 2.44e-35 mstX - - S - - - Membrane-integrating protein Mistic
MCCBHEMI_01971 8.97e-227 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
MCCBHEMI_01972 4.57e-90 yugN - - S - - - YugN-like family
MCCBHEMI_01974 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MCCBHEMI_01975 2.87e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
MCCBHEMI_01976 9.81e-149 ycaC - - Q - - - Isochorismatase family
MCCBHEMI_01977 2.54e-287 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
MCCBHEMI_01978 1.07e-282 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
MCCBHEMI_01979 1.28e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
MCCBHEMI_01980 8.3e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MCCBHEMI_01981 1.79e-261 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
MCCBHEMI_01982 1.53e-108 alaR - - K - - - Transcriptional regulator
MCCBHEMI_01983 3.41e-192 yugF - - I - - - Hydrolase
MCCBHEMI_01984 9.32e-50 yugE - - S - - - Domain of unknown function (DUF1871)
MCCBHEMI_01985 1.98e-278 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MCCBHEMI_01986 1.03e-282 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_01987 3.54e-82 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
MCCBHEMI_01988 7.27e-151 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
MCCBHEMI_01989 2.6e-240 yuxJ - - EGP - - - Major facilitator superfamily
MCCBHEMI_01990 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
MCCBHEMI_01991 5.95e-92 yuxK - - S - - - protein conserved in bacteria
MCCBHEMI_01992 2.08e-97 yufK - - S - - - Family of unknown function (DUF5366)
MCCBHEMI_01993 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MCCBHEMI_01994 3.8e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MCCBHEMI_01995 7.9e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
MCCBHEMI_01996 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_01997 1.18e-232 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MCCBHEMI_01998 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MCCBHEMI_02000 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MCCBHEMI_02001 1.49e-88 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MCCBHEMI_02002 1.42e-65 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MCCBHEMI_02003 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MCCBHEMI_02004 1.13e-97 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MCCBHEMI_02005 1.84e-50 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MCCBHEMI_02006 2.84e-77 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
MCCBHEMI_02007 1.76e-77 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
MCCBHEMI_02008 1.15e-147 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCCBHEMI_02009 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_02011 2.45e-77 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
MCCBHEMI_02012 1.87e-11 - - - S - - - DegQ (SacQ) family
MCCBHEMI_02013 1.36e-63 yuzC - - - - - - -
MCCBHEMI_02014 1.12e-285 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
MCCBHEMI_02015 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MCCBHEMI_02016 2.21e-132 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
MCCBHEMI_02017 4.96e-86 yueI - - S - - - Protein of unknown function (DUF1694)
MCCBHEMI_02018 3.17e-50 yueH - - S - - - YueH-like protein
MCCBHEMI_02019 4.3e-44 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
MCCBHEMI_02020 1.15e-232 yueF - - S - - - transporter activity
MCCBHEMI_02021 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
MCCBHEMI_02022 1.83e-123 yueE - - S ko:K06950 - ko00000 phosphohydrolase
MCCBHEMI_02023 4.06e-160 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCCBHEMI_02024 7.38e-98 yueC - - S - - - Family of unknown function (DUF5383)
MCCBHEMI_02025 0.0 yueB - - S - - - type VII secretion protein EsaA
MCCBHEMI_02026 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MCCBHEMI_02027 1.11e-257 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
MCCBHEMI_02028 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
MCCBHEMI_02029 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
MCCBHEMI_02030 1.66e-288 yukF - - QT - - - Transcriptional regulator
MCCBHEMI_02031 7.76e-259 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MCCBHEMI_02032 3.3e-166 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
MCCBHEMI_02033 2.09e-41 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
MCCBHEMI_02034 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCCBHEMI_02035 1.2e-209 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
MCCBHEMI_02036 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
MCCBHEMI_02037 1.23e-273 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MCCBHEMI_02038 1.53e-165 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MCCBHEMI_02039 1.56e-196 eSD - - S ko:K07017 - ko00000 Putative esterase
MCCBHEMI_02040 7.32e-152 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
MCCBHEMI_02041 4.35e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
MCCBHEMI_02042 9.11e-273 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
MCCBHEMI_02043 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MCCBHEMI_02044 1.18e-99 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
MCCBHEMI_02045 2.23e-149 yuiC - - S - - - protein conserved in bacteria
MCCBHEMI_02046 1.95e-47 yuiB - - S - - - Putative membrane protein
MCCBHEMI_02047 3.83e-297 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MCCBHEMI_02048 1.15e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
MCCBHEMI_02050 5.26e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MCCBHEMI_02051 1.13e-114 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
MCCBHEMI_02052 5.14e-168 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MCCBHEMI_02053 1.88e-80 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
MCCBHEMI_02054 1.52e-205 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MCCBHEMI_02055 2.57e-272 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MCCBHEMI_02056 4.81e-50 yuzB - - S - - - Belongs to the UPF0349 family
MCCBHEMI_02057 7.79e-262 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MCCBHEMI_02058 3.17e-71 yuzD - - S - - - protein conserved in bacteria
MCCBHEMI_02059 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
MCCBHEMI_02060 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
MCCBHEMI_02061 9.05e-206 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MCCBHEMI_02062 1.49e-247 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MCCBHEMI_02063 1.37e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MCCBHEMI_02064 6.76e-245 yutH - - S - - - Spore coat protein
MCCBHEMI_02065 3.08e-108 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MCCBHEMI_02066 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MCCBHEMI_02067 3e-93 yutE - - S - - - Protein of unknown function DUF86
MCCBHEMI_02068 3.71e-62 yutD - - S - - - protein conserved in bacteria
MCCBHEMI_02069 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MCCBHEMI_02070 1.26e-245 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
MCCBHEMI_02071 1.53e-164 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
MCCBHEMI_02072 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MCCBHEMI_02073 9.64e-183 yunE - - S ko:K07090 - ko00000 membrane transporter protein
MCCBHEMI_02074 2.36e-213 yunF - - S - - - Protein of unknown function DUF72
MCCBHEMI_02075 2.23e-73 - - - S - - - phosphoglycolate phosphatase activity
MCCBHEMI_02076 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MCCBHEMI_02077 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
MCCBHEMI_02081 4.96e-83 - - - - - - - -
MCCBHEMI_02082 2.17e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_02083 2.55e-287 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MCCBHEMI_02084 6.96e-283 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MCCBHEMI_02085 2.74e-208 bsn - - L - - - Ribonuclease
MCCBHEMI_02086 5.2e-253 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_02087 3.27e-170 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MCCBHEMI_02088 1.71e-202 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
MCCBHEMI_02089 2.91e-199 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MCCBHEMI_02090 7.16e-201 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MCCBHEMI_02091 3.1e-305 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MCCBHEMI_02092 1.24e-233 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MCCBHEMI_02093 6.58e-203 - - - K - - - helix_turn_helix, mercury resistance
MCCBHEMI_02095 5.4e-95 - - - - - - - -
MCCBHEMI_02096 1.96e-27 - - - S - - - Sporulation delaying protein SdpA
MCCBHEMI_02098 1.36e-84 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
MCCBHEMI_02099 1.61e-253 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
MCCBHEMI_02100 1.05e-131 - - - Q - - - ubiE/COQ5 methyltransferase family
MCCBHEMI_02101 2.91e-93 yncE - - S - - - Protein of unknown function (DUF2691)
MCCBHEMI_02102 2.6e-194 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MCCBHEMI_02103 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
MCCBHEMI_02104 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
MCCBHEMI_02105 7.4e-295 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MCCBHEMI_02106 1.75e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
MCCBHEMI_02107 6.34e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MCCBHEMI_02109 4.22e-83 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MCCBHEMI_02110 7.09e-184 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MCCBHEMI_02111 1.15e-135 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
MCCBHEMI_02112 1.51e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MCCBHEMI_02113 5.08e-74 yusD - - S - - - SCP-2 sterol transfer family
MCCBHEMI_02114 2.25e-70 yusE - - CO - - - Thioredoxin
MCCBHEMI_02115 1.52e-75 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
MCCBHEMI_02116 2.99e-53 yusG - - S - - - Protein of unknown function (DUF2553)
MCCBHEMI_02117 4.86e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MCCBHEMI_02118 4.13e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MCCBHEMI_02119 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MCCBHEMI_02120 1.01e-273 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
MCCBHEMI_02121 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
MCCBHEMI_02122 1.72e-10 - - - S - - - YuzL-like protein
MCCBHEMI_02123 7.81e-208 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MCCBHEMI_02124 7.03e-53 - - - - - - - -
MCCBHEMI_02125 3.53e-69 yusN - - M - - - Coat F domain
MCCBHEMI_02126 1.47e-86 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
MCCBHEMI_02127 0.0 yusP - - P - - - Major facilitator superfamily
MCCBHEMI_02128 1.06e-80 yusQ - - S - - - Tautomerase enzyme
MCCBHEMI_02129 7.26e-160 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MCCBHEMI_02130 4.33e-200 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
MCCBHEMI_02131 1.46e-50 yusU - - S - - - Protein of unknown function (DUF2573)
MCCBHEMI_02132 1.06e-191 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MCCBHEMI_02133 2.79e-62 - - - S - - - YusW-like protein
MCCBHEMI_02134 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
MCCBHEMI_02135 1.02e-176 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MCCBHEMI_02136 1.38e-101 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MCCBHEMI_02137 1.5e-295 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MCCBHEMI_02138 3.56e-161 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCCBHEMI_02139 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_02140 2.68e-32 - - - - - - - -
MCCBHEMI_02141 1.28e-196 yuxN - - K - - - Transcriptional regulator
MCCBHEMI_02142 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MCCBHEMI_02143 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
MCCBHEMI_02144 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MCCBHEMI_02145 3e-235 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MCCBHEMI_02146 1.78e-245 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
MCCBHEMI_02147 1.68e-138 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCCBHEMI_02148 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_02149 1.36e-158 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
MCCBHEMI_02150 4.43e-164 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MCCBHEMI_02151 4.04e-126 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MCCBHEMI_02152 8.99e-66 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
MCCBHEMI_02153 9.45e-281 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_02154 3.2e-124 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
MCCBHEMI_02155 3.09e-256 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MCCBHEMI_02156 2.33e-223 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCCBHEMI_02157 5.29e-212 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MCCBHEMI_02158 5.83e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MCCBHEMI_02159 5.79e-214 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
MCCBHEMI_02160 0.0 yvrG - - T - - - Histidine kinase
MCCBHEMI_02161 4.48e-171 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCCBHEMI_02162 1.14e-48 - - - - - - - -
MCCBHEMI_02163 4.4e-132 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
MCCBHEMI_02164 1.88e-21 - - - S - - - YvrJ protein family
MCCBHEMI_02165 5.77e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MCCBHEMI_02166 3.37e-79 yvrL - - S - - - Regulatory protein YrvL
MCCBHEMI_02167 4.65e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MCCBHEMI_02168 1.2e-219 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCCBHEMI_02169 6.08e-234 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCCBHEMI_02170 2.12e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MCCBHEMI_02171 1.31e-154 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MCCBHEMI_02172 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MCCBHEMI_02173 3.05e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
MCCBHEMI_02174 8.3e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MCCBHEMI_02175 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
MCCBHEMI_02176 9.77e-205 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
MCCBHEMI_02177 4.22e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
MCCBHEMI_02178 1.21e-128 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
MCCBHEMI_02179 8.82e-146 yfiK - - K - - - Regulator
MCCBHEMI_02180 1e-235 - - - T - - - Histidine kinase
MCCBHEMI_02181 2.26e-216 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MCCBHEMI_02182 1.05e-234 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MCCBHEMI_02183 2.04e-229 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MCCBHEMI_02184 1.2e-198 yvgN - - S - - - reductase
MCCBHEMI_02185 6.3e-110 yvgO - - - - - - -
MCCBHEMI_02186 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
MCCBHEMI_02187 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MCCBHEMI_02188 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MCCBHEMI_02189 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MCCBHEMI_02190 9.04e-130 yvgT - - S - - - membrane
MCCBHEMI_02191 8.69e-187 - - - S - - - Metallo-peptidase family M12
MCCBHEMI_02192 2.51e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
MCCBHEMI_02193 4.15e-134 bdbD - - O - - - Thioredoxin
MCCBHEMI_02194 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MCCBHEMI_02195 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MCCBHEMI_02196 1.09e-38 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
MCCBHEMI_02197 2.05e-61 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
MCCBHEMI_02198 1.46e-241 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MCCBHEMI_02199 5.95e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MCCBHEMI_02200 4.04e-205 - - - K - - - Helix-turn-helix XRE-family like proteins
MCCBHEMI_02201 2.4e-271 - - - EGP - - - Major Facilitator Superfamily
MCCBHEMI_02202 1.7e-87 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MCCBHEMI_02203 9.39e-184 - - - S ko:K07045 - ko00000 Amidohydrolase
MCCBHEMI_02204 2.82e-316 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCCBHEMI_02205 2.69e-57 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
MCCBHEMI_02206 4.73e-221 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCCBHEMI_02207 1.23e-178 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MCCBHEMI_02208 3.59e-150 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MCCBHEMI_02209 2.24e-151 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MCCBHEMI_02210 5.62e-185 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MCCBHEMI_02211 1.81e-164 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MCCBHEMI_02212 2.71e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MCCBHEMI_02213 2.8e-204 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
MCCBHEMI_02214 1.79e-176 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MCCBHEMI_02215 6.62e-56 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MCCBHEMI_02217 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MCCBHEMI_02218 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MCCBHEMI_02219 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
MCCBHEMI_02220 9.24e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
MCCBHEMI_02221 1.64e-47 yvzC - - K - - - transcriptional
MCCBHEMI_02222 1.07e-89 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
MCCBHEMI_02223 3.12e-90 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MCCBHEMI_02224 1.17e-67 yvaP - - K - - - transcriptional
MCCBHEMI_02225 3.67e-310 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MCCBHEMI_02226 5.89e-153 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MCCBHEMI_02227 7.53e-165 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MCCBHEMI_02228 4.5e-153 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MCCBHEMI_02229 1.73e-158 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_02230 4.93e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MCCBHEMI_02231 2.26e-213 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MCCBHEMI_02232 5.18e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MCCBHEMI_02233 8.79e-263 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MCCBHEMI_02234 3.5e-108 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MCCBHEMI_02235 2.95e-139 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MCCBHEMI_02236 4.95e-217 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MCCBHEMI_02237 5.4e-143 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MCCBHEMI_02238 1.21e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MCCBHEMI_02239 1.88e-125 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MCCBHEMI_02240 1.55e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
MCCBHEMI_02241 3.18e-149 yvbI - - M - - - Membrane
MCCBHEMI_02242 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MCCBHEMI_02243 5.07e-103 yvbK - - K - - - acetyltransferase
MCCBHEMI_02244 4.84e-259 - - - EGP - - - Major facilitator Superfamily
MCCBHEMI_02245 1.79e-217 - - - - - - - -
MCCBHEMI_02246 5.03e-159 - - - S - - - GlcNAc-PI de-N-acetylase
MCCBHEMI_02247 1.13e-182 - - - C - - - WbqC-like protein family
MCCBHEMI_02248 4.3e-180 - - - M - - - Protein involved in cellulose biosynthesis
MCCBHEMI_02249 1.15e-279 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MCCBHEMI_02250 6.48e-215 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
MCCBHEMI_02251 1.55e-274 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MCCBHEMI_02252 9.36e-317 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MCCBHEMI_02253 1.46e-288 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
MCCBHEMI_02254 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MCCBHEMI_02255 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
MCCBHEMI_02256 1.49e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MCCBHEMI_02257 1.55e-274 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MCCBHEMI_02258 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MCCBHEMI_02259 8.1e-238 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MCCBHEMI_02261 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MCCBHEMI_02262 8.72e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
MCCBHEMI_02263 2.53e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCCBHEMI_02265 6.85e-197 yvbU - - K - - - Transcriptional regulator
MCCBHEMI_02266 5.35e-196 yvbV - - EG - - - EamA-like transporter family
MCCBHEMI_02267 6.69e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MCCBHEMI_02269 5.82e-190 gntR - - K - - - RpiR family transcriptional regulator
MCCBHEMI_02270 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MCCBHEMI_02271 1.08e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MCCBHEMI_02272 3.8e-168 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MCCBHEMI_02273 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MCCBHEMI_02274 1.69e-170 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MCCBHEMI_02275 1.46e-264 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MCCBHEMI_02276 1.16e-151 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
MCCBHEMI_02277 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MCCBHEMI_02278 1.88e-292 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MCCBHEMI_02279 4.01e-44 yvfG - - S - - - YvfG protein
MCCBHEMI_02280 2.89e-226 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
MCCBHEMI_02281 2.79e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MCCBHEMI_02282 4.21e-69 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MCCBHEMI_02283 1.4e-133 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MCCBHEMI_02284 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCCBHEMI_02285 1.71e-239 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MCCBHEMI_02286 3.79e-250 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
MCCBHEMI_02287 1.72e-244 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MCCBHEMI_02288 6.11e-256 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
MCCBHEMI_02289 3.24e-252 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MCCBHEMI_02290 4.18e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
MCCBHEMI_02291 9.98e-268 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
MCCBHEMI_02292 1.86e-307 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MCCBHEMI_02293 1.33e-83 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MCCBHEMI_02294 3.12e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MCCBHEMI_02295 2.53e-150 epsA - - M ko:K19420 - ko00000 biosynthesis protein
MCCBHEMI_02296 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
MCCBHEMI_02297 1.01e-310 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
MCCBHEMI_02299 2.28e-108 ywjB - - H - - - RibD C-terminal domain
MCCBHEMI_02300 4.2e-164 - - - CH - - - FAD binding domain
MCCBHEMI_02301 1.76e-101 glx2 - - S - - - Metallo-beta-lactamase superfamily
MCCBHEMI_02302 6.09e-136 yyaS - - S ko:K07149 - ko00000 Membrane
MCCBHEMI_02303 1.27e-108 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCCBHEMI_02304 7.09e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MCCBHEMI_02305 5.34e-65 - - - S - - - Protein of unknown function (DUF3237)
MCCBHEMI_02306 3.4e-43 - - - S - - - Protein of unknown function (DUF1433)
MCCBHEMI_02307 2.31e-30 - - - S - - - Protein of unknown function (DUF1433)
MCCBHEMI_02308 1.98e-16 - - - S - - - Protein of unknown function (DUF1433)
MCCBHEMI_02309 0.0 - - - I - - - Pfam Lipase (class 3)
MCCBHEMI_02310 3.08e-44 - - - - - - - -
MCCBHEMI_02312 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MCCBHEMI_02313 6.22e-268 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
MCCBHEMI_02314 3.26e-227 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
MCCBHEMI_02315 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MCCBHEMI_02316 4.02e-202 yraN - - K - - - Transcriptional regulator
MCCBHEMI_02317 1.57e-258 yraM - - S - - - PrpF protein
MCCBHEMI_02318 6.35e-316 - - - EGP - - - Sugar (and other) transporter
MCCBHEMI_02319 1.31e-108 - - - - - - - -
MCCBHEMI_02320 4.08e-132 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MCCBHEMI_02321 2.85e-64 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
MCCBHEMI_02322 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MCCBHEMI_02323 8.55e-135 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MCCBHEMI_02324 3.14e-228 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCCBHEMI_02325 7.1e-101 - - - M - - - Ribonuclease
MCCBHEMI_02326 1.59e-164 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
MCCBHEMI_02327 6.52e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
MCCBHEMI_02328 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MCCBHEMI_02329 3.51e-223 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MCCBHEMI_02330 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MCCBHEMI_02331 2.98e-112 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MCCBHEMI_02332 4.78e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MCCBHEMI_02333 1.71e-195 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
MCCBHEMI_02334 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
MCCBHEMI_02335 3.36e-230 sasA - - T - - - Histidine kinase
MCCBHEMI_02336 1.49e-153 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCCBHEMI_02337 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MCCBHEMI_02338 2.15e-139 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
MCCBHEMI_02339 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MCCBHEMI_02340 1.72e-162 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MCCBHEMI_02341 1.75e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MCCBHEMI_02342 2.26e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MCCBHEMI_02343 8.89e-289 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MCCBHEMI_02344 5.89e-145 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MCCBHEMI_02345 1.01e-256 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MCCBHEMI_02346 3.83e-173 yvpB - - NU - - - protein conserved in bacteria
MCCBHEMI_02347 1.2e-110 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MCCBHEMI_02348 7.49e-154 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MCCBHEMI_02349 5.06e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MCCBHEMI_02350 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MCCBHEMI_02351 3.36e-270 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MCCBHEMI_02352 8.32e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MCCBHEMI_02353 1.18e-168 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
MCCBHEMI_02354 2.75e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MCCBHEMI_02355 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
MCCBHEMI_02356 1.09e-65 yvlD - - S ko:K08972 - ko00000 Membrane
MCCBHEMI_02357 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MCCBHEMI_02358 4.14e-214 yvlB - - S - - - Putative adhesin
MCCBHEMI_02359 1.79e-61 yvlA - - - - - - -
MCCBHEMI_02360 1.29e-40 yvkN - - - - - - -
MCCBHEMI_02361 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MCCBHEMI_02362 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MCCBHEMI_02363 2.59e-45 csbA - - S - - - protein conserved in bacteria
MCCBHEMI_02364 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
MCCBHEMI_02365 6.77e-121 yvkB - - K - - - Transcriptional regulator
MCCBHEMI_02366 2.46e-290 yvkA - - P - - - -transporter
MCCBHEMI_02368 1.98e-278 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MCCBHEMI_02369 5.83e-72 swrA - - S - - - Swarming motility protein
MCCBHEMI_02370 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MCCBHEMI_02371 4.69e-279 ywoF - - P - - - Right handed beta helix region
MCCBHEMI_02372 5e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MCCBHEMI_02373 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
MCCBHEMI_02374 2.53e-59 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MCCBHEMI_02375 5.39e-189 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MCCBHEMI_02376 1.08e-222 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MCCBHEMI_02377 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MCCBHEMI_02378 4.25e-130 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MCCBHEMI_02379 1.92e-89 - - - - - - - -
MCCBHEMI_02380 3.08e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
MCCBHEMI_02381 2.18e-83 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
MCCBHEMI_02382 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MCCBHEMI_02383 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MCCBHEMI_02384 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MCCBHEMI_02385 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MCCBHEMI_02386 4.44e-105 yviE - - - - - - -
MCCBHEMI_02387 1.63e-206 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
MCCBHEMI_02388 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
MCCBHEMI_02389 4.09e-101 yvyG - - NOU - - - FlgN protein
MCCBHEMI_02390 2.93e-51 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
MCCBHEMI_02391 6.15e-95 yvyF - - S - - - flagellar protein
MCCBHEMI_02392 7.34e-81 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
MCCBHEMI_02393 2.93e-56 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
MCCBHEMI_02394 2.06e-313 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MCCBHEMI_02395 7.77e-198 degV - - S - - - protein conserved in bacteria
MCCBHEMI_02396 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCCBHEMI_02397 8.07e-246 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MCCBHEMI_02398 1.91e-151 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
MCCBHEMI_02399 7.94e-235 yvhJ - - K - - - Transcriptional regulator
MCCBHEMI_02400 8.94e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MCCBHEMI_02401 1.59e-285 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
MCCBHEMI_02402 2.22e-182 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MCCBHEMI_02403 8.08e-138 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
MCCBHEMI_02404 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
MCCBHEMI_02405 5.02e-311 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MCCBHEMI_02406 4.78e-271 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
MCCBHEMI_02407 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCCBHEMI_02408 8.51e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MCCBHEMI_02409 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MCCBHEMI_02410 0.0 lytB - - D - - - Stage II sporulation protein
MCCBHEMI_02411 1.26e-62 - - - - - - - -
MCCBHEMI_02412 1.43e-200 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MCCBHEMI_02413 6.6e-263 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MCCBHEMI_02414 4.2e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MCCBHEMI_02415 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MCCBHEMI_02416 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MCCBHEMI_02417 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MCCBHEMI_02418 0.0 - - - M - - - Glycosyltransferase like family 2
MCCBHEMI_02419 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
MCCBHEMI_02420 6.85e-179 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MCCBHEMI_02421 5.9e-260 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MCCBHEMI_02422 3.09e-293 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MCCBHEMI_02423 3.29e-232 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MCCBHEMI_02424 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MCCBHEMI_02425 1.43e-204 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MCCBHEMI_02426 2.42e-262 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
MCCBHEMI_02427 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
MCCBHEMI_02428 1.81e-306 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MCCBHEMI_02429 1.73e-224 ywtF_2 - - K - - - Transcriptional regulator
MCCBHEMI_02430 5.43e-195 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MCCBHEMI_02431 1.23e-61 yttA - - S - - - Pfam Transposase IS66
MCCBHEMI_02432 1.6e-287 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MCCBHEMI_02433 1.16e-28 ywtC - - - - - - -
MCCBHEMI_02434 7.41e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MCCBHEMI_02435 4.49e-46 capC - - S ko:K22116 - ko00000 biosynthesis protein
MCCBHEMI_02436 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
MCCBHEMI_02437 9.88e-246 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
MCCBHEMI_02438 4.01e-227 - - - E - - - Spore germination protein
MCCBHEMI_02439 4.54e-247 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
MCCBHEMI_02440 1.08e-221 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
MCCBHEMI_02441 7.09e-195 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MCCBHEMI_02442 3.79e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MCCBHEMI_02443 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MCCBHEMI_02444 5.98e-202 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MCCBHEMI_02445 7.75e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
MCCBHEMI_02446 5.4e-112 batE - - T - - - Sh3 type 3 domain protein
MCCBHEMI_02447 1.17e-112 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
MCCBHEMI_02448 4.33e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MCCBHEMI_02449 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MCCBHEMI_02450 6.98e-211 alsR - - K - - - LysR substrate binding domain
MCCBHEMI_02452 5.9e-297 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MCCBHEMI_02453 8.96e-150 ywrJ - - - - - - -
MCCBHEMI_02454 1.32e-158 cotB - - - ko:K06325 - ko00000 -
MCCBHEMI_02455 9.11e-261 cotH - - M ko:K06330 - ko00000 Spore Coat
MCCBHEMI_02456 2.44e-09 - - - - - - - -
MCCBHEMI_02457 1.35e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MCCBHEMI_02459 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MCCBHEMI_02460 9.36e-106 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MCCBHEMI_02461 7.48e-126 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
MCCBHEMI_02462 8.27e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
MCCBHEMI_02463 7.43e-130 - - - - - - - -
MCCBHEMI_02464 7.6e-62 - - - - - - - -
MCCBHEMI_02465 1.54e-96 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
MCCBHEMI_02466 1.11e-24 - - - - - - - -
MCCBHEMI_02467 5.41e-76 - - - S - - - SUKH-4 immunity protein
MCCBHEMI_02468 9.36e-290 ywqJ - - S - - - Pre-toxin TG
MCCBHEMI_02469 1.36e-48 ywqI - - S - - - Family of unknown function (DUF5344)
MCCBHEMI_02471 4.3e-185 ywqG - - S - - - Domain of unknown function (DUF1963)
MCCBHEMI_02472 6.02e-305 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MCCBHEMI_02473 1.14e-176 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
MCCBHEMI_02474 2.37e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MCCBHEMI_02475 2.08e-144 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
MCCBHEMI_02476 3e-22 - - - - - - - -
MCCBHEMI_02477 0.0 ywqB - - S - - - SWIM zinc finger
MCCBHEMI_02478 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MCCBHEMI_02479 6.34e-194 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MCCBHEMI_02480 2.67e-178 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MCCBHEMI_02481 4.94e-75 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MCCBHEMI_02482 1.83e-74 ywpG - - - - - - -
MCCBHEMI_02483 1.79e-89 ywpF - - S - - - YwpF-like protein
MCCBHEMI_02484 2.54e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MCCBHEMI_02485 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MCCBHEMI_02486 6e-245 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
MCCBHEMI_02487 6.49e-179 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MCCBHEMI_02488 3.46e-172 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MCCBHEMI_02489 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
MCCBHEMI_02490 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
MCCBHEMI_02491 5.3e-93 ywoH - - K - - - transcriptional
MCCBHEMI_02492 3.92e-270 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_02493 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
MCCBHEMI_02494 5.19e-308 ywoD - - EGP - - - Major facilitator superfamily
MCCBHEMI_02495 6.03e-128 yjgF - - Q - - - Isochorismatase family
MCCBHEMI_02496 8.91e-290 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
MCCBHEMI_02497 1.07e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
MCCBHEMI_02498 3.71e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MCCBHEMI_02499 5.56e-130 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
MCCBHEMI_02500 2.5e-90 ywnJ - - S - - - VanZ like family
MCCBHEMI_02501 3.36e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MCCBHEMI_02502 7.6e-113 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
MCCBHEMI_02504 2.45e-88 ywnF - - S - - - Family of unknown function (DUF5392)
MCCBHEMI_02505 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MCCBHEMI_02506 1.33e-77 ywnC - - S - - - Family of unknown function (DUF5362)
MCCBHEMI_02507 6.49e-117 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
MCCBHEMI_02508 3.09e-88 ywnA - - K - - - Transcriptional regulator
MCCBHEMI_02509 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MCCBHEMI_02510 5.97e-79 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
MCCBHEMI_02511 2.26e-65 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
MCCBHEMI_02512 2.41e-16 csbD - - K - - - CsbD-like
MCCBHEMI_02513 1.74e-106 ywmF - - S - - - Peptidase M50
MCCBHEMI_02514 5.81e-114 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MCCBHEMI_02515 2.09e-243 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MCCBHEMI_02516 2.05e-183 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MCCBHEMI_02518 2.79e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MCCBHEMI_02519 1.36e-144 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MCCBHEMI_02520 8.36e-233 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
MCCBHEMI_02521 1.85e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MCCBHEMI_02522 2.57e-169 ywmB - - S - - - TATA-box binding
MCCBHEMI_02523 7.55e-44 ywzB - - S - - - membrane
MCCBHEMI_02524 6.9e-116 ywmA - - - - - - -
MCCBHEMI_02525 3.36e-82 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MCCBHEMI_02526 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MCCBHEMI_02527 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MCCBHEMI_02528 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MCCBHEMI_02529 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCCBHEMI_02530 3.35e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MCCBHEMI_02531 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCCBHEMI_02532 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MCCBHEMI_02533 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
MCCBHEMI_02534 1.3e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MCCBHEMI_02535 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MCCBHEMI_02536 3.53e-123 ywlG - - S - - - Belongs to the UPF0340 family
MCCBHEMI_02537 9.2e-104 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
MCCBHEMI_02538 1.84e-95 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MCCBHEMI_02539 1.86e-116 mntP - - P - - - Probably functions as a manganese efflux pump
MCCBHEMI_02540 2.71e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MCCBHEMI_02541 6.75e-96 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
MCCBHEMI_02542 1e-147 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
MCCBHEMI_02543 4.04e-77 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MCCBHEMI_02545 7.15e-196 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MCCBHEMI_02546 2.06e-240 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MCCBHEMI_02547 2.93e-85 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCCBHEMI_02548 5.09e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MCCBHEMI_02549 6.87e-194 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MCCBHEMI_02550 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MCCBHEMI_02551 6.49e-131 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MCCBHEMI_02552 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MCCBHEMI_02553 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MCCBHEMI_02554 9.65e-223 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
MCCBHEMI_02555 1.59e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MCCBHEMI_02556 3.03e-142 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MCCBHEMI_02557 4.53e-203 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
MCCBHEMI_02558 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
MCCBHEMI_02559 1.84e-117 ywjG - - S - - - Domain of unknown function (DUF2529)
MCCBHEMI_02560 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MCCBHEMI_02561 9.76e-75 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MCCBHEMI_02562 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
MCCBHEMI_02563 4.33e-263 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MCCBHEMI_02564 4.62e-225 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MCCBHEMI_02565 3.23e-58 ywjC - - - - - - -
MCCBHEMI_02566 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MCCBHEMI_02567 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MCCBHEMI_02568 4.81e-151 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
MCCBHEMI_02569 1.25e-109 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
MCCBHEMI_02570 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
MCCBHEMI_02571 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MCCBHEMI_02572 2.12e-102 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
MCCBHEMI_02573 2.46e-161 ywiC - - S - - - YwiC-like protein
MCCBHEMI_02574 2.47e-163 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
MCCBHEMI_02575 1.05e-269 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MCCBHEMI_02576 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MCCBHEMI_02577 1.09e-94 ywiB - - S - - - protein conserved in bacteria
MCCBHEMI_02579 5.71e-251 ywhL - - CO - - - amine dehydrogenase activity
MCCBHEMI_02580 3.59e-101 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MCCBHEMI_02582 1.73e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MCCBHEMI_02583 6.45e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MCCBHEMI_02584 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MCCBHEMI_02585 4.28e-97 - - - - - - - -
MCCBHEMI_02586 2.07e-116 ywhD - - S - - - YwhD family
MCCBHEMI_02587 1.1e-152 ywhC - - S - - - Peptidase family M50
MCCBHEMI_02588 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
MCCBHEMI_02589 3.29e-90 ywhA - - K - - - Transcriptional regulator
MCCBHEMI_02590 4.79e-307 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
MCCBHEMI_02591 1.37e-113 ywgA - - - ko:K09388 - ko00000 -
MCCBHEMI_02592 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
MCCBHEMI_02593 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
MCCBHEMI_02594 6.18e-139 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
MCCBHEMI_02596 4.41e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
MCCBHEMI_02597 8.77e-110 - - - S - - - membrane
MCCBHEMI_02598 8.2e-196 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_02599 1.83e-209 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
MCCBHEMI_02602 1.6e-210 - - - - - - - -
MCCBHEMI_02604 6.62e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MCCBHEMI_02605 6.57e-200 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_02606 6.54e-207 - - - S - - - Conserved hypothetical protein 698
MCCBHEMI_02607 6.52e-222 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
MCCBHEMI_02608 1.9e-184 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
MCCBHEMI_02609 4.99e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
MCCBHEMI_02610 1.37e-291 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MCCBHEMI_02611 9.5e-264 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MCCBHEMI_02612 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MCCBHEMI_02613 7.72e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCCBHEMI_02614 1.63e-174 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MCCBHEMI_02615 4.49e-143 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MCCBHEMI_02616 1.62e-276 ywfA - - EGP - - - -transporter
MCCBHEMI_02617 5.08e-251 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MCCBHEMI_02618 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MCCBHEMI_02619 0.0 rocB - - E - - - arginine degradation protein
MCCBHEMI_02620 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MCCBHEMI_02621 1.43e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MCCBHEMI_02622 4.02e-80 - - - - - - - -
MCCBHEMI_02623 6.39e-110 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
MCCBHEMI_02624 9.86e-201 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MCCBHEMI_02625 4.64e-227 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MCCBHEMI_02626 7.05e-166 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MCCBHEMI_02627 8.63e-212 spsG - - M - - - Spore Coat
MCCBHEMI_02628 1.07e-157 spsF - - M ko:K07257 - ko00000 Spore Coat
MCCBHEMI_02629 2.97e-266 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
MCCBHEMI_02630 6.34e-195 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
MCCBHEMI_02631 1.34e-277 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MCCBHEMI_02632 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
MCCBHEMI_02633 1.68e-179 spsA - - M - - - Spore Coat
MCCBHEMI_02634 1.83e-83 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MCCBHEMI_02635 4.39e-76 ywdK - - S - - - small membrane protein
MCCBHEMI_02636 3.05e-175 ywdJ - - F - - - Xanthine uracil
MCCBHEMI_02639 1.03e-185 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MCCBHEMI_02641 4.96e-113 - - - S - - - Fic/DOC family
MCCBHEMI_02645 1.21e-233 - - - S - - - Helix-turn-helix domain
MCCBHEMI_02648 5.23e-85 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MCCBHEMI_02649 1.19e-98 - - - S ko:K02004 - ko00000,ko00002,ko02000 bacteriocin-associated integral membrane protein
MCCBHEMI_02662 1.26e-113 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MCCBHEMI_02668 4.77e-16 - - - S - - - YolD-like protein
MCCBHEMI_02670 1.48e-34 - - - - - - - -
MCCBHEMI_02671 2.3e-34 - - - L ko:K03630 - ko00000 RadC-like JAB domain
MCCBHEMI_02673 8.48e-171 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MCCBHEMI_02677 8.62e-57 - - - L ko:K07491 - ko00000 Transposase IS200 like
MCCBHEMI_02678 5.14e-57 nucA - - M - - - Deoxyribonuclease NucA/NucB
MCCBHEMI_02681 1.22e-84 - - - L ko:K07491 - ko00000 Transposase IS200 like
MCCBHEMI_02682 1.14e-257 - - - L ko:K07496 - ko00000 Transposase
MCCBHEMI_02694 2.76e-262 yokA - - L - - - Recombinase
MCCBHEMI_02695 3.79e-23 - - - S - - - Regulatory protein YrvL
MCCBHEMI_02697 1.7e-150 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 FMN-dependent dehydrogenase
MCCBHEMI_02699 8.78e-170 - - - Q ko:K04784,ko:K12240 ko01053,map01053 ko00000,ko00001,ko01004,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCCBHEMI_02700 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MCCBHEMI_02701 4.92e-245 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MCCBHEMI_02702 0.0 - - - IQ - - - AMP-binding enzyme
MCCBHEMI_02703 2.89e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
MCCBHEMI_02705 6.32e-86 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
MCCBHEMI_02706 9.08e-202 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_02707 2.42e-215 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MCCBHEMI_02708 1.02e-200 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MCCBHEMI_02709 5.14e-191 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
MCCBHEMI_02710 7.08e-160 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_02711 1.24e-258 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MCCBHEMI_02712 1.33e-159 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCCBHEMI_02713 2.04e-204 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
MCCBHEMI_02714 6.31e-172 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_02715 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
MCCBHEMI_02716 3.58e-152 ywaF - - S - - - Integral membrane protein
MCCBHEMI_02717 5.93e-263 yttB - - EGP - - - Major facilitator superfamily
MCCBHEMI_02718 1.47e-171 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MCCBHEMI_02719 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
MCCBHEMI_02720 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MCCBHEMI_02721 8.6e-69 ytwF - - P - - - Sulfurtransferase
MCCBHEMI_02722 8.97e-96 - - - M - - - Acetyltransferase (GNAT) domain
MCCBHEMI_02723 7.13e-313 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MCCBHEMI_02724 1.17e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MCCBHEMI_02725 1.72e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MCCBHEMI_02726 8.73e-297 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MCCBHEMI_02727 1.89e-230 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_02728 3.57e-35 yteV - - S - - - Sporulation protein Cse60
MCCBHEMI_02729 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
MCCBHEMI_02730 1.9e-292 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
MCCBHEMI_02731 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCCBHEMI_02732 6.03e-160 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MCCBHEMI_02733 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
MCCBHEMI_02734 1.92e-149 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MCCBHEMI_02735 1.21e-251 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
MCCBHEMI_02736 3.89e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
MCCBHEMI_02737 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
MCCBHEMI_02738 1.41e-214 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MCCBHEMI_02739 1.23e-129 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MCCBHEMI_02740 3.65e-201 ytlQ - - - - - - -
MCCBHEMI_02741 5.32e-214 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MCCBHEMI_02742 3.42e-198 ytmP - - M - - - Phosphotransferase
MCCBHEMI_02743 4.54e-59 ytzH - - S - - - YtzH-like protein
MCCBHEMI_02744 7.21e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MCCBHEMI_02745 1.21e-205 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MCCBHEMI_02746 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MCCBHEMI_02747 1.17e-67 ytzB - - S - - - small secreted protein
MCCBHEMI_02748 1.32e-253 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
MCCBHEMI_02749 4.39e-97 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
MCCBHEMI_02750 2.23e-75 ytpP - - CO - - - Thioredoxin
MCCBHEMI_02751 2.21e-186 ytpQ - - S - - - Belongs to the UPF0354 family
MCCBHEMI_02752 9.89e-138 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MCCBHEMI_02753 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MCCBHEMI_02754 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MCCBHEMI_02755 2.16e-25 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MCCBHEMI_02756 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
MCCBHEMI_02757 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
MCCBHEMI_02758 1.8e-248 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MCCBHEMI_02759 7.72e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MCCBHEMI_02760 1.23e-184 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MCCBHEMI_02761 1.71e-145 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MCCBHEMI_02762 8.46e-285 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
MCCBHEMI_02763 1.01e-141 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MCCBHEMI_02764 3.32e-154 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MCCBHEMI_02765 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MCCBHEMI_02766 1.41e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MCCBHEMI_02767 2.07e-62 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MCCBHEMI_02768 7.21e-154 ygaZ - - E - - - AzlC protein
MCCBHEMI_02769 3.69e-189 - - - K - - - Transcriptional regulator
MCCBHEMI_02770 6.5e-189 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MCCBHEMI_02771 3.74e-162 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MCCBHEMI_02773 0.00016 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MCCBHEMI_02775 4.77e-270 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MCCBHEMI_02776 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MCCBHEMI_02777 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
MCCBHEMI_02778 1.68e-109 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MCCBHEMI_02779 1.34e-138 yttP - - K - - - Transcriptional regulator
MCCBHEMI_02780 6.84e-186 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MCCBHEMI_02781 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MCCBHEMI_02782 1.26e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MCCBHEMI_02783 5.93e-261 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MCCBHEMI_02784 3.05e-280 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MCCBHEMI_02785 4.15e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
MCCBHEMI_02786 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MCCBHEMI_02787 0.0 ytcJ - - S - - - amidohydrolase
MCCBHEMI_02788 5.03e-191 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MCCBHEMI_02789 1.32e-227 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
MCCBHEMI_02790 9.22e-104 yteJ - - S - - - RDD family
MCCBHEMI_02791 1.03e-146 ytfI - - S - - - Protein of unknown function (DUF2953)
MCCBHEMI_02792 1.37e-99 ytfJ - - S - - - Sporulation protein YtfJ
MCCBHEMI_02793 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MCCBHEMI_02794 1.05e-225 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MCCBHEMI_02795 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MCCBHEMI_02796 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
MCCBHEMI_02797 8.67e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MCCBHEMI_02798 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MCCBHEMI_02800 1.33e-180 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCCBHEMI_02801 2.31e-163 ytkL - - S - - - Belongs to the UPF0173 family
MCCBHEMI_02802 3.87e-303 ytoI - - K - - - transcriptional regulator containing CBS domains
MCCBHEMI_02803 3.44e-60 ytpI - - S - - - YtpI-like protein
MCCBHEMI_02804 7.37e-223 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
MCCBHEMI_02805 1.17e-30 - - - - - - - -
MCCBHEMI_02806 2.54e-112 ytrI - - - - - - -
MCCBHEMI_02807 1.12e-71 ytrH - - S - - - Sporulation protein YtrH
MCCBHEMI_02808 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MCCBHEMI_02809 1.92e-283 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MCCBHEMI_02810 2.08e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MCCBHEMI_02811 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MCCBHEMI_02812 1.33e-228 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MCCBHEMI_02813 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MCCBHEMI_02814 2.71e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
MCCBHEMI_02815 1.16e-246 ytvI - - S - - - sporulation integral membrane protein YtvI
MCCBHEMI_02816 1.92e-96 ytwI - - S - - - membrane
MCCBHEMI_02817 8.21e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MCCBHEMI_02818 6.26e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
MCCBHEMI_02819 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
MCCBHEMI_02820 5.62e-165 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCCBHEMI_02821 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
MCCBHEMI_02822 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MCCBHEMI_02823 2.05e-195 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MCCBHEMI_02824 4.52e-135 ytaF - - P - - - Probably functions as a manganese efflux pump
MCCBHEMI_02825 3.84e-124 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MCCBHEMI_02826 2.83e-199 ytbE - - S - - - reductase
MCCBHEMI_02827 1.16e-251 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
MCCBHEMI_02828 7.74e-86 ytcD - - K - - - Transcriptional regulator
MCCBHEMI_02829 1.73e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MCCBHEMI_02830 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MCCBHEMI_02831 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MCCBHEMI_02832 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
MCCBHEMI_02833 2.64e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MCCBHEMI_02834 4.78e-135 ytxB - - S - - - SNARE associated Golgi protein
MCCBHEMI_02835 1.23e-191 ytxC - - S - - - YtxC-like family
MCCBHEMI_02836 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MCCBHEMI_02837 2.22e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MCCBHEMI_02838 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_02839 3.36e-164 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
MCCBHEMI_02840 7.85e-67 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
MCCBHEMI_02841 4.22e-145 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MCCBHEMI_02842 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MCCBHEMI_02843 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MCCBHEMI_02844 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MCCBHEMI_02845 2.5e-52 ysdA - - S - - - Membrane
MCCBHEMI_02846 7.1e-83 ysdB - - S - - - Sigma-w pathway protein YsdB
MCCBHEMI_02847 1.52e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
MCCBHEMI_02848 1.24e-234 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MCCBHEMI_02849 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MCCBHEMI_02850 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
MCCBHEMI_02851 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MCCBHEMI_02852 1.89e-175 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
MCCBHEMI_02853 1.31e-266 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MCCBHEMI_02854 8.03e-314 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MCCBHEMI_02855 9.46e-210 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
MCCBHEMI_02856 1.27e-186 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
MCCBHEMI_02857 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
MCCBHEMI_02858 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
MCCBHEMI_02859 2.22e-312 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
MCCBHEMI_02860 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
MCCBHEMI_02861 1.47e-244 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
MCCBHEMI_02862 8.83e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
MCCBHEMI_02863 2.47e-168 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCCBHEMI_02864 1.27e-248 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MCCBHEMI_02865 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MCCBHEMI_02866 8.46e-213 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCCBHEMI_02867 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MCCBHEMI_02868 3.5e-108 yshB - - S - - - membrane protein, required for colicin V production
MCCBHEMI_02869 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
MCCBHEMI_02870 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MCCBHEMI_02871 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
MCCBHEMI_02872 1.04e-146 ywbB - - S - - - Protein of unknown function (DUF2711)
MCCBHEMI_02873 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MCCBHEMI_02874 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_02875 2.54e-171 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
MCCBHEMI_02876 5.83e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
MCCBHEMI_02877 4.79e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
MCCBHEMI_02878 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
MCCBHEMI_02879 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MCCBHEMI_02880 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MCCBHEMI_02881 9.22e-270 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MCCBHEMI_02882 9.97e-103 yslB - - S - - - Protein of unknown function (DUF2507)
MCCBHEMI_02883 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
MCCBHEMI_02884 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MCCBHEMI_02885 1.77e-188 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MCCBHEMI_02886 8.26e-96 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
MCCBHEMI_02887 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_02888 7.32e-95 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MCCBHEMI_02889 1.29e-193 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MCCBHEMI_02890 1.05e-253 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
MCCBHEMI_02891 2.38e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MCCBHEMI_02892 1.25e-128 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MCCBHEMI_02893 1.52e-114 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MCCBHEMI_02898 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MCCBHEMI_02899 1.45e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MCCBHEMI_02900 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MCCBHEMI_02901 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MCCBHEMI_02902 1.79e-247 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MCCBHEMI_02903 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MCCBHEMI_02904 1.26e-148 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MCCBHEMI_02905 6.44e-239 ysoA - - H - - - Tetratricopeptide repeat
MCCBHEMI_02906 1.79e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MCCBHEMI_02907 2.7e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MCCBHEMI_02908 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
MCCBHEMI_02909 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MCCBHEMI_02910 8.88e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MCCBHEMI_02911 1.8e-110 ysxD - - - - - - -
MCCBHEMI_02912 2.79e-311 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MCCBHEMI_02913 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
MCCBHEMI_02914 6.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MCCBHEMI_02915 1.22e-176 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MCCBHEMI_02916 4e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
MCCBHEMI_02917 1.22e-307 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MCCBHEMI_02918 3.29e-211 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
MCCBHEMI_02919 3.31e-236 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MCCBHEMI_02920 3.61e-34 - - - - - - - -
MCCBHEMI_02921 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MCCBHEMI_02922 2.39e-294 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MCCBHEMI_02923 1.4e-159 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MCCBHEMI_02924 1.12e-195 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
MCCBHEMI_02925 4.58e-128 maf - - D ko:K06287 - ko00000 septum formation protein Maf
MCCBHEMI_02926 2.89e-88 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
MCCBHEMI_02927 0.0 - - - S - - - Recombinase
MCCBHEMI_02928 1.47e-104 - - - S - - - Pfam:Peptidase_M78
MCCBHEMI_02929 1.49e-87 - - - S - - - sequence-specific DNA binding
MCCBHEMI_02930 5.7e-13 - - - K - - - helix-turn-helix
MCCBHEMI_02933 7.32e-32 - - - S - - - Uncharacterized protein YqaH
MCCBHEMI_02935 2.55e-118 - - - S - - - DNA protection
MCCBHEMI_02936 4.18e-210 - - - S - - - AAA domain
MCCBHEMI_02938 1.67e-95 - - - S - - - Protein of unknown function (DUF669)
MCCBHEMI_02939 0.0 - - - S - - - hydrolase activity
MCCBHEMI_02940 1.59e-84 - - - - - - - -
MCCBHEMI_02941 1.39e-124 - - - S - - - nuclease activity
MCCBHEMI_02942 6.12e-106 - - - - - - - -
MCCBHEMI_02945 4.53e-79 - - - - - - - -
MCCBHEMI_02948 1.35e-93 - - - S - - - regulation of transcription, DNA-dependent
MCCBHEMI_02949 8.89e-27 - - - N - - - PFAM YcfA family protein
MCCBHEMI_02954 1.28e-102 - - - L - - - phage terminase small subunit
MCCBHEMI_02955 0.0 - - - S - - - Terminase
MCCBHEMI_02956 5.21e-211 - - - S - - - Phage portal protein
MCCBHEMI_02957 5.86e-106 - - - S - - - peptidase activity
MCCBHEMI_02958 5.76e-194 - - - S - - - capsid protein
MCCBHEMI_02959 1.22e-34 - - - - - - - -
MCCBHEMI_02960 6.93e-51 - - - S - - - Phage gp6-like head-tail connector protein
MCCBHEMI_02961 1.19e-55 - - - S - - - Phage head-tail joining protein
MCCBHEMI_02962 1.14e-64 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MCCBHEMI_02964 4.78e-101 - - - S - - - Phage tail tube protein
MCCBHEMI_02965 1.74e-05 - - - - - - - -
MCCBHEMI_02966 0.0 - - - D - - - phage tail tape measure protein
MCCBHEMI_02967 2.28e-133 - - - S - - - Phage tail protein
MCCBHEMI_02968 1.61e-288 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
MCCBHEMI_02969 0.0 - - - M - - - Pectate lyase superfamily protein
MCCBHEMI_02970 1.5e-210 - - - S - - - Domain of unknown function (DUF2479)
MCCBHEMI_02973 1.36e-77 - - - S - - - Pfam:Phage_holin_4_1
MCCBHEMI_02974 6.76e-162 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MCCBHEMI_02979 5.37e-132 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MCCBHEMI_02980 2.91e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
MCCBHEMI_02981 2.51e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MCCBHEMI_02982 4.64e-106 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
MCCBHEMI_02983 1.61e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MCCBHEMI_02984 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MCCBHEMI_02985 7.6e-177 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MCCBHEMI_02986 4.5e-200 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
MCCBHEMI_02987 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MCCBHEMI_02988 3.35e-73 ysxB - - J ko:K07584 - ko00000 ribosomal protein
MCCBHEMI_02989 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MCCBHEMI_02990 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
MCCBHEMI_02991 5.83e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MCCBHEMI_02992 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MCCBHEMI_02993 4.34e-201 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MCCBHEMI_02994 2.11e-115 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
MCCBHEMI_02995 2.11e-271 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MCCBHEMI_02996 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
MCCBHEMI_02997 7.51e-180 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
MCCBHEMI_02998 5.95e-263 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MCCBHEMI_02999 1.25e-218 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
MCCBHEMI_03000 3.13e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MCCBHEMI_03002 1.16e-118 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
MCCBHEMI_03003 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MCCBHEMI_03004 6.61e-232 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MCCBHEMI_03005 1.39e-28 yrzS - - S - - - Protein of unknown function (DUF2905)
MCCBHEMI_03006 5.55e-244 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MCCBHEMI_03007 6.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MCCBHEMI_03008 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
MCCBHEMI_03009 7.46e-80 yrzE - - S - - - Protein of unknown function (DUF3792)
MCCBHEMI_03010 1.16e-133 yrbG - - S - - - membrane
MCCBHEMI_03011 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCCBHEMI_03012 2.26e-64 yrzD - - S - - - Post-transcriptional regulator
MCCBHEMI_03013 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MCCBHEMI_03014 3.2e-105 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MCCBHEMI_03015 3.56e-59 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
MCCBHEMI_03016 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MCCBHEMI_03017 1.71e-116 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MCCBHEMI_03018 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MCCBHEMI_03019 4.07e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MCCBHEMI_03020 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
MCCBHEMI_03023 9.21e-305 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MCCBHEMI_03024 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MCCBHEMI_03025 1.68e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MCCBHEMI_03026 5.94e-300 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MCCBHEMI_03027 3.74e-83 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_03028 5.53e-265 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MCCBHEMI_03029 9.75e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MCCBHEMI_03030 1.88e-23 yrrB - - S - - - COG0457 FOG TPR repeat
MCCBHEMI_03031 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MCCBHEMI_03032 7.39e-100 yrrD - - S - - - protein conserved in bacteria
MCCBHEMI_03033 4.87e-41 yrzR - - - - - - -
MCCBHEMI_03034 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
MCCBHEMI_03035 3.61e-137 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MCCBHEMI_03036 4.6e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MCCBHEMI_03037 3.93e-183 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MCCBHEMI_03038 1.17e-163 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MCCBHEMI_03039 6.91e-223 yrrI - - S - - - AI-2E family transporter
MCCBHEMI_03040 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MCCBHEMI_03041 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
MCCBHEMI_03042 1.11e-92 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MCCBHEMI_03043 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
MCCBHEMI_03044 9.9e-244 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MCCBHEMI_03045 1.38e-145 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
MCCBHEMI_03046 1.04e-220 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
MCCBHEMI_03047 8.94e-311 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
MCCBHEMI_03048 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MCCBHEMI_03049 5.41e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MCCBHEMI_03050 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
MCCBHEMI_03051 6.53e-120 yrrS - - S - - - Protein of unknown function (DUF1510)
MCCBHEMI_03052 2.53e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
MCCBHEMI_03053 1.06e-147 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
MCCBHEMI_03054 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MCCBHEMI_03055 1.41e-210 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
MCCBHEMI_03056 6.51e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MCCBHEMI_03057 9.51e-47 yrhC - - S - - - YrhC-like protein
MCCBHEMI_03058 4.38e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
MCCBHEMI_03059 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
MCCBHEMI_03060 7.32e-79 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
MCCBHEMI_03061 4.24e-178 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
MCCBHEMI_03062 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
MCCBHEMI_03063 7.64e-113 yrhH - - Q - - - methyltransferase
MCCBHEMI_03064 3.6e-125 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
MCCBHEMI_03065 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MCCBHEMI_03066 5.25e-263 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_03067 3.47e-206 yybE - - K - - - Transcriptional regulator
MCCBHEMI_03068 4.39e-96 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MCCBHEMI_03069 1.31e-212 romA - - S - - - Beta-lactamase superfamily domain
MCCBHEMI_03070 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
MCCBHEMI_03071 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_03072 2.64e-217 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MCCBHEMI_03073 7.87e-157 - - - K - - - Helix-turn-helix domain, rpiR family
MCCBHEMI_03074 2.1e-180 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
MCCBHEMI_03075 1.31e-177 supH - - S - - - hydrolase
MCCBHEMI_03076 6.25e-117 - - - S - - - DinB family
MCCBHEMI_03077 6.51e-281 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_03078 3.17e-127 yqaC - - F - - - adenylate kinase activity
MCCBHEMI_03079 7.57e-114 - - - K - - - Transcriptional regulator PadR-like family
MCCBHEMI_03080 1.25e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
MCCBHEMI_03082 1.17e-158 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCCBHEMI_03083 4.55e-258 - - - EGP - - - Transmembrane secretion effector
MCCBHEMI_03085 9.76e-137 yqeD - - S - - - SNARE associated Golgi protein
MCCBHEMI_03086 2.21e-140 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MCCBHEMI_03087 1.97e-172 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MCCBHEMI_03088 3.83e-174 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
MCCBHEMI_03090 7.28e-122 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
MCCBHEMI_03091 1.08e-269 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MCCBHEMI_03092 1.44e-192 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MCCBHEMI_03093 8.62e-59 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
MCCBHEMI_03094 6.05e-133 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MCCBHEMI_03095 1.13e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
MCCBHEMI_03096 3.83e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MCCBHEMI_03097 4.47e-174 yqeM - - Q - - - Methyltransferase
MCCBHEMI_03098 1.74e-185 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MCCBHEMI_03099 3.09e-122 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
MCCBHEMI_03100 1.27e-134 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MCCBHEMI_03101 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MCCBHEMI_03102 7.73e-22 - - - S - - - YqzM-like protein
MCCBHEMI_03103 2.37e-228 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MCCBHEMI_03104 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MCCBHEMI_03105 1.19e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MCCBHEMI_03106 6.13e-278 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
MCCBHEMI_03107 2.88e-69 yqxA - - S - - - Protein of unknown function (DUF3679)
MCCBHEMI_03108 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MCCBHEMI_03109 7.02e-268 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MCCBHEMI_03110 1.07e-237 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MCCBHEMI_03111 7.27e-107 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MCCBHEMI_03112 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MCCBHEMI_03113 4.72e-264 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MCCBHEMI_03114 2.2e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
MCCBHEMI_03115 2.29e-177 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MCCBHEMI_03116 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
MCCBHEMI_03117 3.45e-195 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
MCCBHEMI_03118 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MCCBHEMI_03119 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
MCCBHEMI_03120 6.47e-287 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
MCCBHEMI_03121 1.22e-186 yqfA - - S - - - UPF0365 protein
MCCBHEMI_03122 2.1e-47 yqfB - - - - - - -
MCCBHEMI_03123 3.57e-61 yqfC - - S - - - sporulation protein YqfC
MCCBHEMI_03124 2.91e-275 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
MCCBHEMI_03125 2.37e-222 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
MCCBHEMI_03126 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
MCCBHEMI_03127 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MCCBHEMI_03128 8.76e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MCCBHEMI_03129 2.73e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MCCBHEMI_03130 2.01e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MCCBHEMI_03131 6e-24 - - - S - - - YqzL-like protein
MCCBHEMI_03132 2.31e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MCCBHEMI_03133 2.03e-220 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MCCBHEMI_03134 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MCCBHEMI_03135 3.41e-144 ccpN - - K - - - CBS domain
MCCBHEMI_03136 1.75e-188 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MCCBHEMI_03137 4.54e-111 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
MCCBHEMI_03138 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MCCBHEMI_03139 8e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MCCBHEMI_03140 5.4e-80 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MCCBHEMI_03141 1.58e-157 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MCCBHEMI_03142 9.92e-265 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MCCBHEMI_03143 4.12e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MCCBHEMI_03144 7.12e-57 yqfQ - - S - - - YqfQ-like protein
MCCBHEMI_03145 1.12e-303 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MCCBHEMI_03146 7.53e-208 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MCCBHEMI_03147 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
MCCBHEMI_03148 2.47e-195 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MCCBHEMI_03149 2.63e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
MCCBHEMI_03150 1.13e-139 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
MCCBHEMI_03151 3.9e-79 yqfX - - S - - - membrane
MCCBHEMI_03152 1.09e-253 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MCCBHEMI_03153 5.95e-59 yqfZ - - M ko:K06417 - ko00000 LysM domain
MCCBHEMI_03154 5.98e-165 yqgB - - S - - - Protein of unknown function (DUF1189)
MCCBHEMI_03155 7.59e-97 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
MCCBHEMI_03156 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
MCCBHEMI_03157 5.94e-283 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
MCCBHEMI_03158 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
MCCBHEMI_03159 4.32e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MCCBHEMI_03160 2.48e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MCCBHEMI_03161 1.14e-196 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
MCCBHEMI_03162 2.99e-179 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MCCBHEMI_03163 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MCCBHEMI_03164 5.65e-96 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MCCBHEMI_03165 3.42e-68 yqzD - - - - - - -
MCCBHEMI_03166 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MCCBHEMI_03167 7.01e-116 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MCCBHEMI_03168 9.3e-12 yqgO - - - - - - -
MCCBHEMI_03169 4.47e-270 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MCCBHEMI_03170 1.87e-37 yqgQ - - S - - - Protein conserved in bacteria
MCCBHEMI_03171 1.18e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MCCBHEMI_03172 2.41e-259 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
MCCBHEMI_03173 1.63e-241 yqgU - - - - - - -
MCCBHEMI_03174 2.02e-63 dglA - - S - - - Thiamine-binding protein
MCCBHEMI_03175 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
MCCBHEMI_03176 2e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
MCCBHEMI_03177 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
MCCBHEMI_03178 2.15e-82 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
MCCBHEMI_03180 5.29e-177 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MCCBHEMI_03181 2.59e-295 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MCCBHEMI_03182 3.84e-231 yqxL - - P - - - Mg2 transporter protein
MCCBHEMI_03183 7.12e-254 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MCCBHEMI_03184 4.08e-227 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
MCCBHEMI_03185 9e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
MCCBHEMI_03186 7.32e-90 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
MCCBHEMI_03187 6.31e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
MCCBHEMI_03188 1.4e-27 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MCCBHEMI_03189 1.2e-74 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
MCCBHEMI_03190 9.56e-35 yqzE - - S - - - YqzE-like protein
MCCBHEMI_03191 3.98e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
MCCBHEMI_03192 1.48e-143 yqxM - - - ko:K19433 - ko00000 -
MCCBHEMI_03193 1.91e-95 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
MCCBHEMI_03194 2.37e-177 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
MCCBHEMI_03195 2.27e-71 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
MCCBHEMI_03196 1.3e-29 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
MCCBHEMI_03197 4.01e-191 yqhG - - S - - - Bacterial protein YqhG of unknown function
MCCBHEMI_03198 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MCCBHEMI_03199 2.2e-253 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
MCCBHEMI_03200 1.02e-311 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MCCBHEMI_03201 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MCCBHEMI_03202 2.33e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
MCCBHEMI_03203 1.25e-201 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MCCBHEMI_03204 1.14e-96 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MCCBHEMI_03205 1.25e-203 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MCCBHEMI_03206 8.59e-80 yqhP - - - - - - -
MCCBHEMI_03207 1.12e-215 yqhQ - - S - - - Protein of unknown function (DUF1385)
MCCBHEMI_03208 8.66e-113 yqhR - - S - - - Conserved membrane protein YqhR
MCCBHEMI_03209 9.6e-246 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MCCBHEMI_03210 9.69e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MCCBHEMI_03211 1.64e-48 yqhV - - S - - - Protein of unknown function (DUF2619)
MCCBHEMI_03212 1.52e-212 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
MCCBHEMI_03213 2.71e-109 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
MCCBHEMI_03214 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
MCCBHEMI_03215 5.28e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
MCCBHEMI_03216 3.02e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
MCCBHEMI_03217 1.74e-129 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
MCCBHEMI_03218 6.18e-144 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
MCCBHEMI_03219 1.88e-86 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
MCCBHEMI_03220 2.59e-83 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MCCBHEMI_03221 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MCCBHEMI_03222 7.86e-87 yqhY - - S - - - protein conserved in bacteria
MCCBHEMI_03223 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MCCBHEMI_03224 2.51e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MCCBHEMI_03225 3.77e-308 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCCBHEMI_03226 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCCBHEMI_03227 1.02e-200 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MCCBHEMI_03228 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MCCBHEMI_03229 4.65e-194 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
MCCBHEMI_03230 1.03e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MCCBHEMI_03231 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MCCBHEMI_03232 1.35e-298 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
MCCBHEMI_03233 2.05e-185 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MCCBHEMI_03234 2.14e-260 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MCCBHEMI_03237 4.72e-265 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MCCBHEMI_03239 3.85e-144 - - - K - - - Protein of unknown function (DUF1232)
MCCBHEMI_03240 2.52e-119 - - - P - - - Probably functions as a manganese efflux pump
MCCBHEMI_03242 2.26e-126 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
MCCBHEMI_03243 1.72e-162 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MCCBHEMI_03244 1.21e-266 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MCCBHEMI_03245 6.5e-186 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
MCCBHEMI_03246 1.33e-255 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
MCCBHEMI_03247 9.85e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MCCBHEMI_03248 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
MCCBHEMI_03249 7.1e-199 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MCCBHEMI_03250 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
MCCBHEMI_03251 0.0 bkdR - - KT - - - Transcriptional regulator
MCCBHEMI_03252 6.51e-193 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
MCCBHEMI_03253 5.27e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MCCBHEMI_03254 3.17e-259 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
MCCBHEMI_03255 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MCCBHEMI_03256 7.24e-218 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MCCBHEMI_03257 1.15e-233 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MCCBHEMI_03258 1.56e-264 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MCCBHEMI_03259 7.9e-215 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MCCBHEMI_03260 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
MCCBHEMI_03261 3.77e-171 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MCCBHEMI_03262 6.03e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MCCBHEMI_03263 1.31e-159 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MCCBHEMI_03264 6.23e-217 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
MCCBHEMI_03265 1.39e-118 yqjB - - S - - - protein conserved in bacteria
MCCBHEMI_03267 1.49e-92 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
MCCBHEMI_03268 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MCCBHEMI_03269 5.04e-257 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
MCCBHEMI_03270 9.51e-182 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MCCBHEMI_03271 1.36e-36 yqzJ - - - - - - -
MCCBHEMI_03272 1.91e-294 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MCCBHEMI_03273 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MCCBHEMI_03274 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MCCBHEMI_03275 1.72e-214 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MCCBHEMI_03276 7.39e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MCCBHEMI_03277 8.38e-185 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MCCBHEMI_03278 7.32e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MCCBHEMI_03279 3.44e-61 - - - S - - - GlpM protein
MCCBHEMI_03280 4.7e-204 - - - K - - - LysR substrate binding domain
MCCBHEMI_03281 5.05e-121 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MCCBHEMI_03282 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MCCBHEMI_03283 3.08e-180 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MCCBHEMI_03284 3.19e-213 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MCCBHEMI_03285 7.35e-175 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MCCBHEMI_03286 6.49e-304 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MCCBHEMI_03287 3.01e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MCCBHEMI_03289 5.73e-206 yueF - - S - - - transporter activity
MCCBHEMI_03291 3.08e-74 - - - S - - - YolD-like protein
MCCBHEMI_03292 2.04e-293 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MCCBHEMI_03293 2.7e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
MCCBHEMI_03294 1.92e-08 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
MCCBHEMI_03295 1.36e-212 yqkA - - K - - - GrpB protein
MCCBHEMI_03296 1.22e-76 yqkB - - S - - - Belongs to the HesB IscA family
MCCBHEMI_03297 6.5e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
MCCBHEMI_03298 1.97e-208 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MCCBHEMI_03299 3.06e-15 yqkE - - S - - - Protein of unknown function (DUF3886)
MCCBHEMI_03300 8.16e-212 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MCCBHEMI_03301 5.78e-10 - - - S - - - Protein of unknown function (DUF3936)
MCCBHEMI_03302 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MCCBHEMI_03303 4.98e-272 yqxK - - L - - - DNA helicase
MCCBHEMI_03304 2.32e-75 ansR - - K - - - Transcriptional regulator
MCCBHEMI_03305 4.88e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
MCCBHEMI_03306 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
MCCBHEMI_03307 1.02e-312 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MCCBHEMI_03308 2.66e-306 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MCCBHEMI_03309 5.05e-33 - - - - - - - -
MCCBHEMI_03310 2.87e-43 yqkK - - - - - - -
MCCBHEMI_03311 2.04e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MCCBHEMI_03312 3.08e-102 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MCCBHEMI_03313 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
MCCBHEMI_03314 4.38e-211 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
MCCBHEMI_03315 1.31e-289 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MCCBHEMI_03316 4.3e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MCCBHEMI_03317 6.51e-269 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MCCBHEMI_03318 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
MCCBHEMI_03319 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MCCBHEMI_03320 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCCBHEMI_03321 9.1e-141 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
MCCBHEMI_03322 7.71e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
MCCBHEMI_03323 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
MCCBHEMI_03324 9.17e-241 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
MCCBHEMI_03325 3.57e-74 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
MCCBHEMI_03326 1.2e-138 - - - S ko:K06407 - ko00000 stage V sporulation protein
MCCBHEMI_03327 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
MCCBHEMI_03328 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MCCBHEMI_03329 1.17e-194 ypuA - - S - - - Secreted protein
MCCBHEMI_03330 1.18e-103 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MCCBHEMI_03331 1.03e-100 ccdC1 - - O - - - Protein of unknown function (DUF1453)
MCCBHEMI_03332 2.03e-125 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MCCBHEMI_03333 7.86e-68 ypuD - - - - - - -
MCCBHEMI_03334 1.24e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MCCBHEMI_03335 4.45e-141 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MCCBHEMI_03336 4.36e-283 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MCCBHEMI_03337 1.4e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MCCBHEMI_03338 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCCBHEMI_03339 2.06e-114 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
MCCBHEMI_03341 3.47e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MCCBHEMI_03342 1.85e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MCCBHEMI_03343 1.69e-106 ypuI - - S - - - Protein of unknown function (DUF3907)
MCCBHEMI_03344 4.08e-269 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MCCBHEMI_03345 6.22e-134 spmA - - S ko:K06373 - ko00000 Spore maturation protein
MCCBHEMI_03346 7.39e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
MCCBHEMI_03347 4.98e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MCCBHEMI_03348 4.14e-126 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MCCBHEMI_03349 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
MCCBHEMI_03350 3.09e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MCCBHEMI_03351 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCCBHEMI_03352 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_03353 1.79e-132 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MCCBHEMI_03354 2.82e-217 rsiX - - - - - - -
MCCBHEMI_03355 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCCBHEMI_03356 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MCCBHEMI_03357 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
MCCBHEMI_03358 5.74e-242 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
MCCBHEMI_03359 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MCCBHEMI_03360 1.57e-124 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
MCCBHEMI_03361 8.85e-110 ypbE - - M - - - Lysin motif
MCCBHEMI_03362 3.73e-109 ypbF - - S - - - Protein of unknown function (DUF2663)
MCCBHEMI_03363 3.39e-182 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MCCBHEMI_03364 7.9e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MCCBHEMI_03365 7.37e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MCCBHEMI_03366 5.93e-236 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
MCCBHEMI_03367 2.61e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
MCCBHEMI_03368 2.15e-203 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
MCCBHEMI_03369 1.34e-312 ypeB - - H ko:K06313 - ko00000 sporulation protein
MCCBHEMI_03370 4.64e-72 ypfA - - M - - - Flagellar protein YcgR
MCCBHEMI_03371 1.12e-17 - - - S - - - Family of unknown function (DUF5359)
MCCBHEMI_03372 6.49e-143 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MCCBHEMI_03373 9.1e-261 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MCCBHEMI_03374 1.22e-230 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MCCBHEMI_03375 1.96e-12 - - - S - - - YpzI-like protein
MCCBHEMI_03376 6.38e-129 yphA - - - - - - -
MCCBHEMI_03377 2.86e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MCCBHEMI_03378 9.14e-240 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MCCBHEMI_03379 1.13e-23 yphE - - S - - - Protein of unknown function (DUF2768)
MCCBHEMI_03380 2.47e-166 yphF - - - - - - -
MCCBHEMI_03382 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MCCBHEMI_03383 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MCCBHEMI_03384 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
MCCBHEMI_03385 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MCCBHEMI_03386 2.68e-175 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MCCBHEMI_03387 2.6e-167 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MCCBHEMI_03388 6.56e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MCCBHEMI_03389 2.01e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MCCBHEMI_03390 9.33e-177 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
MCCBHEMI_03391 9.34e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MCCBHEMI_03392 2.68e-252 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MCCBHEMI_03393 8.09e-77 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MCCBHEMI_03394 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MCCBHEMI_03395 3.8e-201 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MCCBHEMI_03396 8.1e-159 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MCCBHEMI_03397 1.88e-143 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MCCBHEMI_03398 6.2e-284 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MCCBHEMI_03399 2.65e-176 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MCCBHEMI_03400 2.67e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MCCBHEMI_03401 2.69e-255 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MCCBHEMI_03402 7.98e-292 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MCCBHEMI_03403 3.64e-290 ypiA - - S - - - COG0457 FOG TPR repeat
MCCBHEMI_03404 7.45e-129 ypiB - - S - - - Belongs to the UPF0302 family
MCCBHEMI_03405 5.12e-96 ypiF - - S - - - Protein of unknown function (DUF2487)
MCCBHEMI_03406 2.27e-124 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
MCCBHEMI_03407 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
MCCBHEMI_03408 9.48e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
MCCBHEMI_03409 1.23e-125 ypjA - - S - - - membrane
MCCBHEMI_03410 3.12e-177 ypjB - - S - - - sporulation protein
MCCBHEMI_03411 2.32e-279 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MCCBHEMI_03412 6.13e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MCCBHEMI_03413 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
MCCBHEMI_03414 9.38e-187 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MCCBHEMI_03415 3.58e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
MCCBHEMI_03416 2.29e-163 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
MCCBHEMI_03417 4.05e-266 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
MCCBHEMI_03418 8.44e-264 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MCCBHEMI_03419 3.52e-227 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MCCBHEMI_03420 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MCCBHEMI_03421 4.82e-194 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MCCBHEMI_03422 1.63e-82 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MCCBHEMI_03423 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MCCBHEMI_03424 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
MCCBHEMI_03425 1.16e-96 ypmB - - S - - - protein conserved in bacteria
MCCBHEMI_03426 1.57e-278 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MCCBHEMI_03427 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
MCCBHEMI_03428 8.05e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
MCCBHEMI_03429 1.4e-155 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MCCBHEMI_03430 7.63e-112 ypoC - - - - - - -
MCCBHEMI_03431 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MCCBHEMI_03432 8.49e-144 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MCCBHEMI_03433 5.22e-226 yppC - - S - - - Protein of unknown function (DUF2515)
MCCBHEMI_03438 2.01e-65 yppG - - S - - - YppG-like protein
MCCBHEMI_03439 1.7e-82 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MCCBHEMI_03440 6.99e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
MCCBHEMI_03441 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MCCBHEMI_03442 2.35e-285 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
MCCBHEMI_03444 8.12e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
MCCBHEMI_03445 3.67e-126 ypsA - - S - - - Belongs to the UPF0398 family
MCCBHEMI_03446 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MCCBHEMI_03447 7.25e-272 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MCCBHEMI_03448 6.91e-31 - - - S - - - YpzG-like protein
MCCBHEMI_03450 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
MCCBHEMI_03451 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MCCBHEMI_03452 2.06e-122 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MCCBHEMI_03453 5.66e-295 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
MCCBHEMI_03454 3.11e-09 - - - S - - - Bacillus cereus group antimicrobial protein
MCCBHEMI_03455 6.86e-61 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
MCCBHEMI_03456 2.7e-131 - - - J - - - Acetyltransferase (GNAT) domain
MCCBHEMI_03457 6.6e-255 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
MCCBHEMI_03458 3.19e-111 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
MCCBHEMI_03459 0.0 ypbR - - S - - - Dynamin family
MCCBHEMI_03460 3e-45 ypbS - - S - - - Protein of unknown function (DUF2533)
MCCBHEMI_03461 1.64e-10 - - - - - - - -
MCCBHEMI_03462 1.77e-205 ypcP - - L - - - 5'3' exonuclease
MCCBHEMI_03464 3.51e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
MCCBHEMI_03465 3.96e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MCCBHEMI_03466 7.41e-153 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
MCCBHEMI_03467 6.37e-38 ypeQ - - S - - - Zinc-finger
MCCBHEMI_03468 5.37e-48 - - - S - - - Protein of unknown function (DUF2564)
MCCBHEMI_03469 4.27e-16 degR - - - - - - -
MCCBHEMI_03470 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MCCBHEMI_03471 1.01e-272 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MCCBHEMI_03472 9e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MCCBHEMI_03474 2.98e-108 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MCCBHEMI_03475 1.24e-116 yagB - - S ko:K06950 - ko00000 phosphohydrolase
MCCBHEMI_03476 2.44e-198 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
MCCBHEMI_03477 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
MCCBHEMI_03478 1.38e-98 yphP - - S - - - Belongs to the UPF0403 family
MCCBHEMI_03479 2.63e-167 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
MCCBHEMI_03480 1.21e-143 ypjP - - S - - - YpjP-like protein
MCCBHEMI_03481 2.53e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MCCBHEMI_03482 2.2e-110 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MCCBHEMI_03483 9.83e-141 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MCCBHEMI_03484 7.14e-141 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
MCCBHEMI_03485 5.36e-208 yplP - - K - - - Transcriptional regulator
MCCBHEMI_03486 7.88e-305 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MCCBHEMI_03487 3.66e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
MCCBHEMI_03488 2.61e-130 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MCCBHEMI_03489 3.62e-167 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
MCCBHEMI_03490 2.55e-122 ypmS - - S - - - protein conserved in bacteria
MCCBHEMI_03491 3.91e-88 ypoP - - K - - - transcriptional
MCCBHEMI_03492 3.3e-131 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MCCBHEMI_03493 7.09e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MCCBHEMI_03494 7.44e-129 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MCCBHEMI_03495 1.97e-312 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MCCBHEMI_03496 3.08e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
MCCBHEMI_03497 2.56e-248 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
MCCBHEMI_03498 9.47e-245 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_03499 2.06e-129 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCCBHEMI_03500 1.89e-189 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MCCBHEMI_03501 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
MCCBHEMI_03502 8.68e-311 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MCCBHEMI_03503 5.36e-219 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MCCBHEMI_03504 1.18e-172 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MCCBHEMI_03505 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MCCBHEMI_03506 3.31e-198 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MCCBHEMI_03507 1.66e-223 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MCCBHEMI_03508 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MCCBHEMI_03509 1.73e-218 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MCCBHEMI_03510 4.1e-291 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
MCCBHEMI_03511 1.94e-245 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MCCBHEMI_03512 5.99e-210 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
MCCBHEMI_03513 1.63e-198 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MCCBHEMI_03514 7.99e-195 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MCCBHEMI_03515 6.33e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCCBHEMI_03516 6.25e-221 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_03517 3.14e-180 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MCCBHEMI_03518 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MCCBHEMI_03519 4.53e-72 yxeA - - S - - - Protein of unknown function (DUF1093)
MCCBHEMI_03520 1.66e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MCCBHEMI_03522 9.67e-33 yxeD - - - - - - -
MCCBHEMI_03524 7.69e-30 yxeE - - - - - - -
MCCBHEMI_03527 7.14e-188 yxeH - - S - - - hydrolases of the HAD superfamily
MCCBHEMI_03528 9.22e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MCCBHEMI_03529 1.17e-144 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MCCBHEMI_03530 2.33e-264 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MCCBHEMI_03531 6.37e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
MCCBHEMI_03532 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MCCBHEMI_03533 2.01e-217 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MCCBHEMI_03534 6.57e-292 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
MCCBHEMI_03535 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MCCBHEMI_03536 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
MCCBHEMI_03537 4.06e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MCCBHEMI_03538 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MCCBHEMI_03539 4.64e-33 - - - - - - - -
MCCBHEMI_03540 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_03541 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MCCBHEMI_03542 2.44e-94 yxiE - - T - - - Belongs to the universal stress protein A family
MCCBHEMI_03543 8.65e-201 yxxF - - EG - - - EamA-like transporter family
MCCBHEMI_03544 6.09e-254 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MCCBHEMI_03545 0.0 wapA - - M - - - COG3209 Rhs family protein
MCCBHEMI_03548 1.98e-74 yxxG - - - - - - -
MCCBHEMI_03549 4.14e-85 yxiG - - - - - - -
MCCBHEMI_03553 2.72e-99 - - - - - - - -
MCCBHEMI_03554 4.85e-141 - - - - - - - -
MCCBHEMI_03556 7.3e-28 - - - - - - - -
MCCBHEMI_03558 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MCCBHEMI_03559 3.21e-276 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
MCCBHEMI_03560 2.11e-183 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MCCBHEMI_03561 4.82e-176 bglS - - M - - - licheninase activity
MCCBHEMI_03562 1.83e-280 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MCCBHEMI_03563 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MCCBHEMI_03564 9.35e-68 yxiS - - - - - - -
MCCBHEMI_03565 3.46e-115 - - - T - - - Domain of unknown function (DUF4163)
MCCBHEMI_03566 2.49e-262 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MCCBHEMI_03567 4.2e-187 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
MCCBHEMI_03568 1e-271 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MCCBHEMI_03569 7.69e-105 yxjI - - S - - - LURP-one-related
MCCBHEMI_03572 6.38e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MCCBHEMI_03573 8.19e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MCCBHEMI_03574 2.1e-117 yxkC - - S - - - Domain of unknown function (DUF4352)
MCCBHEMI_03576 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MCCBHEMI_03577 6.08e-198 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MCCBHEMI_03578 2.51e-259 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MCCBHEMI_03579 2.05e-192 yxkH - - G - - - Polysaccharide deacetylase
MCCBHEMI_03580 3.56e-284 cimH - - C - - - COG3493 Na citrate symporter
MCCBHEMI_03581 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MCCBHEMI_03582 2.52e-238 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
MCCBHEMI_03583 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
MCCBHEMI_03584 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
MCCBHEMI_03585 3.69e-193 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MCCBHEMI_03586 2.12e-315 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
MCCBHEMI_03587 3.46e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MCCBHEMI_03588 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MCCBHEMI_03589 5.48e-260 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MCCBHEMI_03590 1.05e-227 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MCCBHEMI_03591 1.45e-203 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
MCCBHEMI_03592 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MCCBHEMI_03593 3.04e-297 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCCBHEMI_03594 1.08e-63 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_03595 1.32e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_03596 3.33e-286 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MCCBHEMI_03597 3.71e-67 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
MCCBHEMI_03598 1.53e-212 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MCCBHEMI_03599 3.26e-229 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCCBHEMI_03600 1.29e-217 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCCBHEMI_03601 1.42e-139 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MCCBHEMI_03602 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MCCBHEMI_03603 3.67e-65 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
MCCBHEMI_03604 7.19e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCCBHEMI_03605 5.64e-66 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_03606 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MCCBHEMI_03607 3.17e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MCCBHEMI_03608 2.84e-285 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MCCBHEMI_03609 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCCBHEMI_03610 2.45e-289 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
MCCBHEMI_03611 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCCBHEMI_03612 3.51e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MCCBHEMI_03613 7.25e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MCCBHEMI_03614 2.16e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
MCCBHEMI_03615 9.62e-204 gspA - - M - - - General stress
MCCBHEMI_03616 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MCCBHEMI_03617 1.23e-310 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCCBHEMI_03618 5.06e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
MCCBHEMI_03619 5.24e-278 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
MCCBHEMI_03620 1.52e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
MCCBHEMI_03621 4.37e-142 ywbG - - M - - - effector of murein hydrolase
MCCBHEMI_03622 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MCCBHEMI_03623 2.29e-200 ywbI - - K - - - Transcriptional regulator
MCCBHEMI_03624 3.64e-166 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MCCBHEMI_03625 2.33e-140 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MCCBHEMI_03626 5.65e-245 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
MCCBHEMI_03627 1.17e-190 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
MCCBHEMI_03628 5.66e-296 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
MCCBHEMI_03629 1.58e-138 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MCCBHEMI_03630 1.44e-155 - - - S - - - Streptomycin biosynthesis protein StrF
MCCBHEMI_03631 6.64e-162 - - - H - - - Methionine biosynthesis protein MetW
MCCBHEMI_03633 2.98e-126 - - - K - - - Bacterial regulatory proteins, tetR family
MCCBHEMI_03634 7.8e-78 gtcA - - S - - - GtrA-like protein
MCCBHEMI_03635 4.56e-267 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MCCBHEMI_03636 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MCCBHEMI_03637 5.74e-48 ydaS - - S - - - membrane
MCCBHEMI_03638 3.01e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MCCBHEMI_03639 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MCCBHEMI_03640 2.84e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MCCBHEMI_03641 1.08e-80 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MCCBHEMI_03642 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
MCCBHEMI_03643 1.83e-91 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
MCCBHEMI_03644 7e-267 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MCCBHEMI_03645 1.1e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
MCCBHEMI_03646 1.07e-36 - - - S - - - PFAM Stress responsive alpha-beta barrel
MCCBHEMI_03647 2.83e-55 - - - S - - - Ketosteroid isomerase-related protein
MCCBHEMI_03648 2.02e-160 ucpA - - IQ - - - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCCBHEMI_03649 1.32e-152 - - - K - - - WYL domain
MCCBHEMI_03650 6.39e-234 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCCBHEMI_03651 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MCCBHEMI_03653 2.18e-167 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MCCBHEMI_03654 9.04e-317 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_03655 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MCCBHEMI_03656 6.09e-27 ywdA - - - - - - -
MCCBHEMI_03657 1.38e-185 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MCCBHEMI_03659 1.01e-186 ywdF - - S - - - Glycosyltransferase like family 2
MCCBHEMI_03660 2.42e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MCCBHEMI_03661 2.41e-57 ywdI - - S - - - Family of unknown function (DUF5327)
MCCBHEMI_03664 2.89e-84 hxlR - - K - - - transcriptional
MCCBHEMI_03665 1.31e-131 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
MCCBHEMI_03666 1.73e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
MCCBHEMI_03667 2.67e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
MCCBHEMI_03668 2.99e-85 nin - - S - - - Competence protein J (ComJ)
MCCBHEMI_03669 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MCCBHEMI_03670 7.52e-65 - - - S - - - Protein of unknown function (DUF2680)
MCCBHEMI_03671 4.26e-93 yckC - - S - - - membrane
MCCBHEMI_03672 1.24e-276 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MCCBHEMI_03673 3.59e-283 yciC - - S - - - GTPases (G3E family)
MCCBHEMI_03674 1.41e-49 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MCCBHEMI_03675 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MCCBHEMI_03676 8.14e-73 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
MCCBHEMI_03677 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MCCBHEMI_03678 2.31e-233 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MCCBHEMI_03679 6.5e-287 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
MCCBHEMI_03680 2.11e-309 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MCCBHEMI_03681 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MCCBHEMI_03682 1.53e-213 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MCCBHEMI_03683 7.09e-179 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
MCCBHEMI_03684 3.16e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
MCCBHEMI_03685 2.04e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MCCBHEMI_03686 1.12e-286 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_03687 1.3e-168 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
MCCBHEMI_03688 3.54e-189 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MCCBHEMI_03689 6.25e-144 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
MCCBHEMI_03690 6.78e-295 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MCCBHEMI_03691 2.72e-188 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MCCBHEMI_03692 3.18e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
MCCBHEMI_03693 3.16e-97 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
MCCBHEMI_03694 0.0 mdr - - EGP - - - the major facilitator superfamily
MCCBHEMI_03695 2.21e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MCCBHEMI_03696 5.26e-17 - - - S - - - RDD family
MCCBHEMI_03697 1.04e-53 ycgB - - - - - - -
MCCBHEMI_03698 8.16e-287 ycgA - - S - - - Membrane
MCCBHEMI_03699 1.92e-262 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
MCCBHEMI_03700 4.54e-207 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MCCBHEMI_03701 3.48e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MCCBHEMI_03702 2.12e-291 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MCCBHEMI_03704 2.54e-267 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
MCCBHEMI_03705 1.36e-245 yceH - - P - - - Belongs to the TelA family
MCCBHEMI_03706 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
MCCBHEMI_03707 4.28e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
MCCBHEMI_03708 3.36e-136 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MCCBHEMI_03709 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MCCBHEMI_03710 9.56e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
MCCBHEMI_03711 8.68e-231 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCCBHEMI_03712 1.38e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MCCBHEMI_03713 1.15e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MCCBHEMI_03714 2.33e-213 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MCCBHEMI_03715 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MCCBHEMI_03716 1.26e-171 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
MCCBHEMI_03717 3.74e-221 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
MCCBHEMI_03718 3.75e-114 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MCCBHEMI_03719 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MCCBHEMI_03720 6.62e-299 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MCCBHEMI_03721 8.9e-208 ycdA - - S - - - Domain of unknown function (DUF5105)
MCCBHEMI_03722 1.84e-210 yccK - - C - - - Aldo keto reductase
MCCBHEMI_03723 8.53e-246 yccF - - K ko:K07039 - ko00000 SEC-C motif
MCCBHEMI_03724 1.44e-141 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MCCBHEMI_03725 3.35e-125 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MCCBHEMI_03726 3.1e-307 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
MCCBHEMI_03727 1.58e-246 ycbU - - E - - - Selenocysteine lyase
MCCBHEMI_03728 1.7e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MCCBHEMI_03729 4.75e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MCCBHEMI_03730 5.03e-35 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MCCBHEMI_03731 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
MCCBHEMI_03732 3.67e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
MCCBHEMI_03733 4.68e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
MCCBHEMI_03734 3.23e-75 ydfQ - - CO - - - Thioredoxin
MCCBHEMI_03735 3.27e-83 ydfP - - S ko:K15977 - ko00000 DoxX
MCCBHEMI_03736 1.02e-233 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MCCBHEMI_03737 4.7e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
MCCBHEMI_03738 1.23e-197 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MCCBHEMI_03739 3.3e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
MCCBHEMI_03740 9.37e-158 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
MCCBHEMI_03741 2.43e-197 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
MCCBHEMI_03742 2.93e-261 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MCCBHEMI_03743 1.85e-239 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MCCBHEMI_03744 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MCCBHEMI_03745 2.57e-224 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
MCCBHEMI_03746 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MCCBHEMI_03747 1.73e-247 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MCCBHEMI_03748 4.32e-265 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCCBHEMI_03749 1.78e-239 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
MCCBHEMI_03750 8.03e-51 ybfN - - - - - - -
MCCBHEMI_03751 4.85e-191 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MCCBHEMI_03752 3.37e-110 ybfM - - S - - - SNARE associated Golgi protein
MCCBHEMI_03753 9.04e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MCCBHEMI_03754 4.22e-267 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MCCBHEMI_03755 2.15e-241 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
MCCBHEMI_03756 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
MCCBHEMI_03757 1.92e-105 - - - S - - - LXG domain of WXG superfamily
MCCBHEMI_03759 3e-158 ybfI - - K - - - AraC-like ligand binding domain
MCCBHEMI_03760 1.57e-146 ybfH - - EG - - - EamA-like transporter family
MCCBHEMI_03761 1.16e-13 ybfG - - M - - - Domain of unknown function (DUF1906)
MCCBHEMI_03762 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
MCCBHEMI_03764 6.44e-261 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
MCCBHEMI_03765 1.43e-23 - - - S - - - Protein of unknown function (DUF2651)
MCCBHEMI_03766 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
MCCBHEMI_03767 2.63e-209 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
MCCBHEMI_03768 3.11e-23 - - - S - - - Protein of unknown function (DUF2651)
MCCBHEMI_03770 1.77e-60 - - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MCCBHEMI_03771 0.0 ybeC - - E - - - amino acid
MCCBHEMI_03772 2.17e-52 ybyB - - - - - - -
MCCBHEMI_03773 4.25e-136 yqeB - - - - - - -
MCCBHEMI_03774 2.48e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
MCCBHEMI_03775 1.05e-102 - - - S - - - Domain of unknown function (DUF4879)
MCCBHEMI_03776 3.22e-33 - - - - - - - -
MCCBHEMI_03777 1.82e-229 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MCCBHEMI_03778 2.75e-241 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MCCBHEMI_03779 7.12e-204 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MCCBHEMI_03780 3.19e-129 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
MCCBHEMI_03781 1.07e-233 - - - T - - - COG4585 Signal transduction histidine kinase
MCCBHEMI_03782 1.86e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MCCBHEMI_03783 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MCCBHEMI_03784 1.27e-89 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MCCBHEMI_03785 1.15e-66 - - - S ko:K06518 - ko00000,ko02000 LrgA family
MCCBHEMI_03786 3.49e-134 yxaC - - M - - - effector of murein hydrolase
MCCBHEMI_03787 3.42e-196 dkgB - - S - - - Aldo/keto reductase family
MCCBHEMI_03788 5.85e-117 - - - H - - - Tellurite resistance protein TehB
MCCBHEMI_03790 0.0 - - - KLT - - - Protein kinase domain
MCCBHEMI_03791 1.15e-128 - - - S - - - ABC-2 family transporter protein
MCCBHEMI_03792 3.33e-187 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MCCBHEMI_03793 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MCCBHEMI_03794 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MCCBHEMI_03795 1.57e-291 ybbR - - S - - - protein conserved in bacteria
MCCBHEMI_03796 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MCCBHEMI_03797 1.7e-146 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MCCBHEMI_03798 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MCCBHEMI_03804 6.2e-98 ybbK - - S - - - Protein of unknown function (DUF523)
MCCBHEMI_03805 9.36e-106 ybbJ - - J - - - acetyltransferase
MCCBHEMI_03806 1.28e-205 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MCCBHEMI_03807 1.41e-301 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_03808 6.18e-300 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
MCCBHEMI_03809 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
MCCBHEMI_03810 4.44e-291 ybbC - - S - - - protein conserved in bacteria
MCCBHEMI_03811 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
MCCBHEMI_03812 2.25e-215 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
MCCBHEMI_03813 5.16e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCCBHEMI_03814 5.99e-224 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCCBHEMI_03815 2.71e-127 ybbA - - S ko:K07017 - ko00000 Putative esterase
MCCBHEMI_03816 7.81e-216 ybaS - - S - - - Na -dependent transporter
MCCBHEMI_03817 2.05e-283 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MCCBHEMI_03818 4.64e-255 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MCCBHEMI_03819 3.02e-228 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
MCCBHEMI_03820 4.97e-311 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MCCBHEMI_03821 3.78e-271 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
MCCBHEMI_03824 2.44e-218 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MCCBHEMI_03825 1.75e-110 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
MCCBHEMI_03826 2.21e-157 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
MCCBHEMI_03827 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MCCBHEMI_03828 2.43e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MCCBHEMI_03829 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
MCCBHEMI_03830 5.96e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MCCBHEMI_03831 1.51e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MCCBHEMI_03832 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MCCBHEMI_03833 1.11e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MCCBHEMI_03834 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
MCCBHEMI_03835 9.24e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MCCBHEMI_03836 1.24e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MCCBHEMI_03837 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MCCBHEMI_03838 8.33e-193 ydjC - - S - - - Abhydrolase domain containing 18
MCCBHEMI_03839 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
MCCBHEMI_03840 3.26e-253 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MCCBHEMI_03841 6.64e-313 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
MCCBHEMI_03842 6.74e-218 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MCCBHEMI_03843 1.47e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
MCCBHEMI_03844 4.36e-143 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
MCCBHEMI_03845 6.45e-222 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MCCBHEMI_03846 3.97e-156 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
MCCBHEMI_03847 4.64e-200 ydjI - - S - - - virion core protein (lumpy skin disease virus)
MCCBHEMI_03848 0.0 oatA - - I - - - Acyltransferase family
MCCBHEMI_03849 8.19e-186 rsiV - - S - - - Protein of unknown function (DUF3298)
MCCBHEMI_03850 8.88e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MCCBHEMI_03851 1.12e-245 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
MCCBHEMI_03852 7.91e-83 ydjM - - M - - - Lytic transglycolase
MCCBHEMI_03853 6.13e-189 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
MCCBHEMI_03855 9.6e-47 ydjO - - S - - - Cold-inducible protein YdjO
MCCBHEMI_03856 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
MCCBHEMI_03857 5.17e-307 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MCCBHEMI_03858 6.34e-180 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MCCBHEMI_03859 7.99e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
MCCBHEMI_03860 1.42e-254 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MCCBHEMI_03861 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
MCCBHEMI_03862 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MCCBHEMI_03863 3.03e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MCCBHEMI_03864 2.6e-316 - - - S - - - Domain of unknown function (DUF4179)
MCCBHEMI_03865 2.04e-268 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MCCBHEMI_03866 1.2e-165 yebC - - M - - - Membrane
MCCBHEMI_03868 7.62e-120 yebE - - S - - - UPF0316 protein
MCCBHEMI_03869 7.68e-39 yebG - - S - - - NETI protein
MCCBHEMI_03870 1.87e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MCCBHEMI_03871 3.44e-282 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MCCBHEMI_03872 1.05e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MCCBHEMI_03873 4.62e-164 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MCCBHEMI_03874 8.96e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MCCBHEMI_03875 7.47e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MCCBHEMI_03876 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MCCBHEMI_03877 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MCCBHEMI_03878 2.53e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MCCBHEMI_03879 9.17e-131 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MCCBHEMI_03880 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MCCBHEMI_03881 6.36e-295 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MCCBHEMI_03882 4.48e-81 - - - K - - - helix_turn_helix ASNC type
MCCBHEMI_03883 1.2e-174 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
MCCBHEMI_03884 2.32e-33 - - - S - - - Protein of unknown function (DUF2892)
MCCBHEMI_03885 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
MCCBHEMI_03886 1.85e-241 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
MCCBHEMI_03887 2.03e-67 yerC - - S - - - protein conserved in bacteria
MCCBHEMI_03888 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
MCCBHEMI_03889 5.04e-163 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MCCBHEMI_03890 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MCCBHEMI_03891 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MCCBHEMI_03892 1.59e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
MCCBHEMI_03893 3.53e-230 yerI - - S - - - homoserine kinase type II (protein kinase fold)
MCCBHEMI_03894 7.98e-156 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MCCBHEMI_03895 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MCCBHEMI_03896 1.05e-59 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCCBHEMI_03897 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MCCBHEMI_03898 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCCBHEMI_03899 4.11e-189 yerO - - K - - - Transcriptional regulator
MCCBHEMI_03900 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MCCBHEMI_03901 8.56e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MCCBHEMI_03902 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MCCBHEMI_03903 9.2e-164 - - - - - - - -
MCCBHEMI_03904 3.57e-146 cll - - - - - - -
MCCBHEMI_03905 3.68e-48 - - - S - - - Plasmid maintenance system killer
MCCBHEMI_03906 1.99e-168 - - - K - - - Pfam:DUF955
MCCBHEMI_03908 1.12e-79 - - - S - - - Protein of unknown function, DUF600
MCCBHEMI_03909 4.26e-99 - - - S - - - Protein of unknown function, DUF600
MCCBHEMI_03910 7.73e-104 - - - S - - - Protein of unknown function, DUF600
MCCBHEMI_03911 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
MCCBHEMI_03912 4.43e-162 yeeN - - K - - - transcriptional regulatory protein
MCCBHEMI_03914 1.61e-137 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
MCCBHEMI_03915 1.32e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
MCCBHEMI_03916 1.34e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
MCCBHEMI_03917 4.26e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
MCCBHEMI_03918 4.44e-111 yesJ - - K - - - Acetyltransferase (GNAT) family
MCCBHEMI_03920 1.26e-147 yetF - - S - - - membrane
MCCBHEMI_03921 1.77e-69 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
MCCBHEMI_03922 2.02e-82 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCCBHEMI_03923 3.41e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MCCBHEMI_03924 9.52e-30 - - - S - - - Uncharacterized small protein (DUF2292)
MCCBHEMI_03925 1.5e-72 - - - H - - - riboflavin kinase activity
MCCBHEMI_03926 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
MCCBHEMI_03927 1.77e-109 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MCCBHEMI_03928 2.87e-247 yetM - - CH - - - FAD binding domain
MCCBHEMI_03929 1.13e-250 yetN - - S - - - Protein of unknown function (DUF3900)
MCCBHEMI_03930 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MCCBHEMI_03932 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MCCBHEMI_03933 1.4e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
MCCBHEMI_03934 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
MCCBHEMI_03935 2.78e-222 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
MCCBHEMI_03936 1.08e-270 yfnE - - S - - - Glycosyltransferase like family 2
MCCBHEMI_03937 5.43e-227 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
MCCBHEMI_03938 5.57e-271 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MCCBHEMI_03939 4.95e-305 yfnA - - E ko:K03294 - ko00000 amino acid
MCCBHEMI_03940 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MCCBHEMI_03941 3.69e-165 yfmS - - NT - - - chemotaxis protein
MCCBHEMI_03942 1.93e-211 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MCCBHEMI_03943 2.92e-257 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
MCCBHEMI_03944 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MCCBHEMI_03945 8.36e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
MCCBHEMI_03946 3.06e-249 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
MCCBHEMI_03947 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MCCBHEMI_03948 3.3e-260 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
MCCBHEMI_03949 6.53e-229 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
MCCBHEMI_03950 1.39e-32 - - - S - - - Protein of unknown function (DUF3212)
MCCBHEMI_03951 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
MCCBHEMI_03952 3.18e-299 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MCCBHEMI_03953 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MCCBHEMI_03956 5.81e-63 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
MCCBHEMI_03957 1.1e-256 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MCCBHEMI_03958 3.96e-71 - - - - - - - -
MCCBHEMI_03959 6.85e-99 - - - K - - - Transcriptional regulator
MCCBHEMI_03960 5.18e-125 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MCCBHEMI_03961 3.05e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
MCCBHEMI_03962 1.9e-15 - - - S - - - Protein of unknown function (DUF3888)
MCCBHEMI_03963 9.37e-90 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
MCCBHEMI_03964 5.32e-143 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MCCBHEMI_03965 1.17e-130 - - - S - - - Protein of unknown function (DUF2812)
MCCBHEMI_03966 6.49e-65 - - - K - - - Transcriptional regulator PadR-like family
MCCBHEMI_03967 2.32e-299 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MCCBHEMI_03968 1.97e-238 ydeG - - EGP - - - Major facilitator superfamily
MCCBHEMI_03969 4.07e-219 - - - S - - - Patatin-like phospholipase
MCCBHEMI_03971 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
MCCBHEMI_03972 2.32e-93 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCCBHEMI_03973 4.9e-195 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
MCCBHEMI_03974 4.74e-191 - - - S - - - SNARE associated Golgi protein
MCCBHEMI_03975 1.39e-123 yrkC - - G - - - Cupin domain
MCCBHEMI_03976 3.52e-106 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
MCCBHEMI_03977 1.04e-187 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
MCCBHEMI_03979 1.52e-240 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MCCBHEMI_03980 4.13e-62 ydeH - - - - - - -
MCCBHEMI_03981 5.42e-208 - - - S - - - Sodium Bile acid symporter family
MCCBHEMI_03982 2.29e-251 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
MCCBHEMI_03983 3.08e-79 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MCCBHEMI_03984 3.66e-277 nhaC_1 - - C - - - antiporter
MCCBHEMI_03985 3.98e-315 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MCCBHEMI_03986 1.28e-131 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
MCCBHEMI_03987 1.64e-238 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
MCCBHEMI_03988 2.13e-129 ydeS - - K - - - Transcriptional regulator
MCCBHEMI_03989 3.48e-191 ydeK - - EG - - - -transporter
MCCBHEMI_03990 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MCCBHEMI_03991 1.16e-62 yraD - - M ko:K06439 - ko00000 Spore coat protein
MCCBHEMI_03992 1.45e-34 yraE - - - ko:K06440 - ko00000 -
MCCBHEMI_03993 3.98e-278 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MCCBHEMI_03994 3.92e-83 yraF - - M - - - Spore coat protein
MCCBHEMI_03995 1.16e-47 yraG - - - ko:K06440 - ko00000 -
MCCBHEMI_03996 2.47e-164 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
MCCBHEMI_03997 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
MCCBHEMI_03998 1.06e-117 ynaD - - J - - - Acetyltransferase (GNAT) domain
MCCBHEMI_03999 1.43e-190 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MCCBHEMI_04000 1.89e-248 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
MCCBHEMI_04001 7.2e-264 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MCCBHEMI_04002 2.24e-33 tnpB - - L - - - Belongs to the 'phage' integrase family
MCCBHEMI_04003 2.91e-248 recN - - L ko:K03631,ko:K07459 - ko00000,ko03400 DNA synthesis involved in DNA repair
MCCBHEMI_04004 2.08e-208 ygxA - - S - - - Nucleotidyltransferase-like
MCCBHEMI_04005 2.71e-74 ygzB - - S - - - UPF0295 protein
MCCBHEMI_04006 6.8e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MCCBHEMI_04007 1.9e-109 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
MCCBHEMI_04008 1.27e-309 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MCCBHEMI_04009 1.76e-237 ygaE - - S - - - Membrane
MCCBHEMI_04010 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
MCCBHEMI_04011 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MCCBHEMI_04012 1.4e-49 ygaB - - S - - - YgaB-like protein
MCCBHEMI_04013 9.58e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
MCCBHEMI_04014 1.73e-169 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCCBHEMI_04015 1.47e-49 yfhS - - - - - - -
MCCBHEMI_04016 1.9e-258 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
MCCBHEMI_04017 4.29e-229 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
MCCBHEMI_04018 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MCCBHEMI_04019 4.51e-235 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MCCBHEMI_04020 7.32e-214 - - - S - - - Alpha/beta hydrolase family
MCCBHEMI_04021 5.95e-50 yfhL - - S - - - SdpI/YhfL protein family
MCCBHEMI_04022 1.14e-112 yfhK - - T - - - Bacterial SH3 domain homologues
MCCBHEMI_04023 1.49e-58 yfhJ - - S - - - WVELL protein
MCCBHEMI_04024 3.29e-205 mpr - - M - - - Belongs to the peptidase S1B family
MCCBHEMI_04026 9.55e-267 yfhI - - EGP - - - -transporter
MCCBHEMI_04027 3.24e-60 yfhH - - S - - - Protein of unknown function (DUF1811)
MCCBHEMI_04028 2.27e-176 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MCCBHEMI_04029 7.53e-209 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
MCCBHEMI_04031 6.01e-33 yfhD - - S - - - YfhD-like protein
MCCBHEMI_04032 4.39e-133 yfhC - - C - - - nitroreductase
MCCBHEMI_04033 4.95e-191 yfhB - - S - - - PhzF family
MCCBHEMI_04034 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MCCBHEMI_04035 1.43e-101 yfiV - - K - - - transcriptional
MCCBHEMI_04036 0.0 yfiU - - EGP - - - the major facilitator superfamily
MCCBHEMI_04037 3.53e-123 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
MCCBHEMI_04038 1.37e-59 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MCCBHEMI_04039 1.45e-224 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MCCBHEMI_04040 1.29e-128 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MCCBHEMI_04041 1e-119 padR - - K - - - transcriptional
MCCBHEMI_04042 1.15e-211 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MCCBHEMI_04043 5.67e-197 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MCCBHEMI_04044 7.86e-82 yfiD3 - - S - - - DoxX
MCCBHEMI_04045 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MCCBHEMI_04046 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
MCCBHEMI_04047 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
MCCBHEMI_04048 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MCCBHEMI_04049 1.28e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MCCBHEMI_04050 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MCCBHEMI_04051 3.29e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
MCCBHEMI_04052 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
MCCBHEMI_04053 1.04e-305 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MCCBHEMI_04054 1.51e-262 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MCCBHEMI_04055 5.7e-237 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MCCBHEMI_04056 1.15e-236 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MCCBHEMI_04057 2.86e-102 yfjM - - S - - - Psort location Cytoplasmic, score
MCCBHEMI_04058 1.4e-240 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MCCBHEMI_04059 1.06e-59 - - - S - - - YfzA-like protein
MCCBHEMI_04060 8.54e-244 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)