ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
FGFKEIIK_00001 1.43e-153 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
FGFKEIIK_00002 4.73e-221 yeiH - - S - - - Membrane
FGFKEIIK_00005 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
FGFKEIIK_00006 1.69e-128 XK27_10720 - - D - - - peptidase activity
FGFKEIIK_00007 8.54e-98 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
FGFKEIIK_00008 1.33e-07 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
FGFKEIIK_00009 2.9e-43 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
FGFKEIIK_00010 2.82e-132 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
FGFKEIIK_00011 1.1e-143 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
FGFKEIIK_00012 3.85e-72 hsdS 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K07317 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
FGFKEIIK_00013 1.21e-112 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_00014 9.08e-51 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_00015 7.07e-40 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_00016 9.84e-225 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_00017 1.29e-40 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_00018 4.58e-156 - - - L - - - Transposase
FGFKEIIK_00019 1.53e-212 - - - L ko:K07497 - ko00000 integrase core domain
FGFKEIIK_00020 8.77e-56 cspA - - K ko:K03704 - ko00000,ko03000 Cold-Shock Protein
FGFKEIIK_00021 2.63e-44 - - - K - - - Cold shock protein domain
FGFKEIIK_00022 2.45e-211 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
FGFKEIIK_00023 1.2e-207 whiA - - K ko:K09762 - ko00000 May be required for sporulation
FGFKEIIK_00024 3.04e-232 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
FGFKEIIK_00025 2.08e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
FGFKEIIK_00026 1.88e-176 yejC - - S - - - cyclic nucleotide-binding protein
FGFKEIIK_00027 2.81e-22 - - - D - - - nuclear chromosome segregation
FGFKEIIK_00028 2.72e-122 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
FGFKEIIK_00029 7.17e-172 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
FGFKEIIK_00030 1.17e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
FGFKEIIK_00031 3.72e-159 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FGFKEIIK_00032 1.84e-83 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
FGFKEIIK_00033 1.82e-17 - - - - - - - -
FGFKEIIK_00034 2.05e-42 - - - - - - - -
FGFKEIIK_00036 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
FGFKEIIK_00037 3.85e-279 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
FGFKEIIK_00038 1.32e-106 ypmB - - S - - - Protein conserved in bacteria
FGFKEIIK_00039 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
FGFKEIIK_00040 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
FGFKEIIK_00041 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
FGFKEIIK_00042 9.61e-247 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
FGFKEIIK_00043 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FGFKEIIK_00044 6.01e-246 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
FGFKEIIK_00045 6.79e-91 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
FGFKEIIK_00046 4.43e-82 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FGFKEIIK_00047 2.52e-30 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FGFKEIIK_00048 3e-121 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
FGFKEIIK_00049 1.27e-71 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
FGFKEIIK_00050 5.78e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
FGFKEIIK_00051 2.47e-222 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
FGFKEIIK_00052 1.98e-40 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 rRNA binding
FGFKEIIK_00053 0.0 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_00054 9.94e-209 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_00055 1.68e-106 - - - L - - - Helix-turn-helix domain
FGFKEIIK_00056 1.5e-28 - - - L - - - Helix-turn-helix domain
FGFKEIIK_00057 0.0 vpr 3.4.21.96 - O ko:K01361,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
FGFKEIIK_00058 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
FGFKEIIK_00059 2.52e-263 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
FGFKEIIK_00060 1.92e-36 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
FGFKEIIK_00061 7.99e-283 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_00062 1.53e-212 - - - L ko:K07497 - ko00000 integrase core domain
FGFKEIIK_00063 3.22e-156 - - - L - - - Transposase
FGFKEIIK_00064 1.11e-114 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FGFKEIIK_00065 2.38e-53 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FGFKEIIK_00066 1.19e-49 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FGFKEIIK_00067 4.04e-86 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FGFKEIIK_00068 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
FGFKEIIK_00069 6.6e-158 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
FGFKEIIK_00070 5.7e-124 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FGFKEIIK_00071 1.52e-122 - - - S - - - ECF transporter, substrate-specific component
FGFKEIIK_00072 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
FGFKEIIK_00073 2.2e-212 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
FGFKEIIK_00074 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGFKEIIK_00076 9.47e-282 - - - L - - - Belongs to the 'phage' integrase family
FGFKEIIK_00077 5.02e-37 - - - K - - - transcriptional
FGFKEIIK_00078 2.15e-27 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
FGFKEIIK_00082 1.9e-30 - - - - - - - -
FGFKEIIK_00083 1.88e-191 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
FGFKEIIK_00084 0.0 - - - S ko:K06919 - ko00000 DNA primase
FGFKEIIK_00088 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
FGFKEIIK_00089 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
FGFKEIIK_00090 3.19e-25 - - - L ko:K07483 - ko00000 transposase activity
FGFKEIIK_00091 9.69e-72 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_00092 5.03e-43 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_00093 2.06e-46 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_00094 1.09e-311 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FGFKEIIK_00095 4.98e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FGFKEIIK_00096 2.07e-301 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
FGFKEIIK_00097 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FGFKEIIK_00098 3.08e-14 - - - S - - - D-Ala-teichoic acid biosynthesis protein
FGFKEIIK_00099 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
FGFKEIIK_00100 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
FGFKEIIK_00101 2.1e-135 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
FGFKEIIK_00102 4.29e-228 - - - S - - - 37-kD nucleoid-associated bacterial protein
FGFKEIIK_00103 1.24e-298 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGFKEIIK_00104 1.2e-140 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FGFKEIIK_00105 3.18e-199 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FGFKEIIK_00106 5.57e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGFKEIIK_00107 2.65e-145 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
FGFKEIIK_00108 4.54e-240 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FGFKEIIK_00109 1.92e-197 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
FGFKEIIK_00110 1.77e-236 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
FGFKEIIK_00111 6.83e-227 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
FGFKEIIK_00112 1.39e-61 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
FGFKEIIK_00113 7.72e-295 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
FGFKEIIK_00114 1.93e-12 - - - - - - - -
FGFKEIIK_00115 5.37e-41 - - - - - - - -
FGFKEIIK_00116 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FGFKEIIK_00117 2.95e-186 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division protein DivIVA
FGFKEIIK_00118 4.82e-184 ylmH - - T ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 S4 RNA-binding domain
FGFKEIIK_00119 2.56e-46 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
FGFKEIIK_00120 1.04e-124 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
FGFKEIIK_00121 1.14e-158 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FGFKEIIK_00122 2.64e-303 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FGFKEIIK_00123 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FGFKEIIK_00124 1.01e-237 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
FGFKEIIK_00125 1.9e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGFKEIIK_00126 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGFKEIIK_00127 2.68e-12 - - - S - - - Protein of unknown function (DUF3165)
FGFKEIIK_00128 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
FGFKEIIK_00129 1.76e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
FGFKEIIK_00130 7.8e-38 yqgQ - - S - - - protein conserved in bacteria
FGFKEIIK_00131 5.82e-105 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
FGFKEIIK_00132 3.18e-118 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
FGFKEIIK_00133 4.5e-150 pppA 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
FGFKEIIK_00134 1.71e-288 - - - V - - - D-alanyl-D-alanine carboxypeptidase
FGFKEIIK_00135 6.73e-145 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
FGFKEIIK_00136 2.71e-236 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
FGFKEIIK_00137 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FGFKEIIK_00138 2.18e-73 - - - S - - - Domain of unknown function (DUF4430)
FGFKEIIK_00139 4.09e-95 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
FGFKEIIK_00140 5.7e-188 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
FGFKEIIK_00141 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
FGFKEIIK_00142 1.85e-128 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
FGFKEIIK_00143 2.66e-77 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
FGFKEIIK_00144 1.13e-09 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
FGFKEIIK_00145 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
FGFKEIIK_00146 1.73e-169 - - - S - - - Protein conserved in bacteria
FGFKEIIK_00147 0.0 - - - S - - - KAP family P-loop domain
FGFKEIIK_00148 4.17e-163 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
FGFKEIIK_00151 4.75e-82 - - - - - - - -
FGFKEIIK_00152 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
FGFKEIIK_00153 1.45e-131 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
FGFKEIIK_00154 4.34e-07 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
FGFKEIIK_00155 1.03e-27 - - - S - - - Protein of unknown function (DUF2974)
FGFKEIIK_00156 4.51e-14 - - - S - - - Protein of unknown function (DUF2974)
FGFKEIIK_00157 6.94e-146 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGFKEIIK_00158 1.14e-35 - - - P - - - Hemerythrin HHE cation binding domain protein
FGFKEIIK_00159 2.83e-196 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
FGFKEIIK_00160 2.49e-105 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGFKEIIK_00161 1.02e-149 pgm - - G - - - Phosphoglycerate mutase
FGFKEIIK_00162 3.13e-222 - - - S ko:K07025 - ko00000 hydrolase
FGFKEIIK_00163 2.16e-29 - - - - - - - -
FGFKEIIK_00164 4.3e-216 - - - M - - - LysM domain
FGFKEIIK_00165 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
FGFKEIIK_00166 7.54e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_00167 0.0 - - - L - - - helicase
FGFKEIIK_00168 1.83e-86 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
FGFKEIIK_00170 6.38e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
FGFKEIIK_00171 0.0 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_00172 2.97e-45 XK27_12190 - - S - - - protein conserved in bacteria
FGFKEIIK_00174 1.09e-112 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
FGFKEIIK_00175 1.8e-308 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_00176 3.62e-60 - - - S - - - CHY zinc finger
FGFKEIIK_00177 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
FGFKEIIK_00178 1.23e-228 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
FGFKEIIK_00180 1.66e-91 ytxH - - S - - - General stress protein
FGFKEIIK_00181 1.14e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FGFKEIIK_00182 1.51e-190 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FGFKEIIK_00183 3.49e-219 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FGFKEIIK_00184 1.45e-55 WQ51_05770 - - KT - - - PspC domain
FGFKEIIK_00185 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
FGFKEIIK_00187 4.63e-199 XK27_03015 - - S ko:K07089 - ko00000 permease
FGFKEIIK_00188 4.65e-189 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
FGFKEIIK_00189 6.13e-236 - - - S - - - CRISPR-associated protein Csn2 subfamily St
FGFKEIIK_00190 8.44e-71 - - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FGFKEIIK_00191 1.61e-221 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FGFKEIIK_00192 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FGFKEIIK_00193 3.1e-124 - - - - - - - -
FGFKEIIK_00194 2.23e-35 - - - E - - - GDSL-like Lipase/Acylhydrolase
FGFKEIIK_00195 1.61e-54 - - - S - - - CAAX protease self-immunity
FGFKEIIK_00196 7.8e-35 - - - S - - - CAAX protease self-immunity
FGFKEIIK_00197 2.15e-45 - - - - - - - -
FGFKEIIK_00199 4.98e-85 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
FGFKEIIK_00200 3.12e-77 - - - S - - - Protein of unknown function (DUF1722)
FGFKEIIK_00202 3.82e-95 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
FGFKEIIK_00203 1.24e-85 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
FGFKEIIK_00204 3.6e-51 - - - L ko:K07483 - ko00000 transposase activity
FGFKEIIK_00205 6.38e-249 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_00206 5.56e-124 - - - - - - - -
FGFKEIIK_00207 7.72e-66 - - - J - - - Acetyltransferase (GNAT) domain
FGFKEIIK_00208 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGFKEIIK_00209 5.21e-126 mip - - S - - - hydroperoxide reductase activity
FGFKEIIK_00210 1.56e-256 - - - I - - - acyl-CoA dehydrogenase
FGFKEIIK_00211 4.07e-199 ydiA - - P ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 C4-dicarboxylate transporter malic acid transport protein
FGFKEIIK_00212 0.0 msrR - - K - - - Transcriptional regulator
FGFKEIIK_00213 3.43e-197 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
FGFKEIIK_00214 2.28e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGFKEIIK_00215 6.18e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
FGFKEIIK_00216 6.06e-223 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
FGFKEIIK_00217 1.48e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
FGFKEIIK_00218 1.92e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
FGFKEIIK_00219 1.29e-279 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGFKEIIK_00220 1.24e-258 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGFKEIIK_00221 4.21e-208 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGFKEIIK_00222 8.04e-158 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
FGFKEIIK_00223 1.45e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
FGFKEIIK_00224 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
FGFKEIIK_00225 2.22e-34 WQ51_00785 - - - - - - -
FGFKEIIK_00226 1.75e-314 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FGFKEIIK_00227 1.03e-101 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
FGFKEIIK_00228 1.03e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
FGFKEIIK_00229 6.38e-130 yyaQ - - V - - - Protein conserved in bacteria
FGFKEIIK_00230 2.03e-35 XK27_07735 - - S - - - YjbR
FGFKEIIK_00231 1.34e-235 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
FGFKEIIK_00232 7e-268 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
FGFKEIIK_00233 1.08e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
FGFKEIIK_00234 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGFKEIIK_00235 5.69e-105 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
FGFKEIIK_00236 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FGFKEIIK_00237 1.5e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
FGFKEIIK_00238 5.15e-93 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
FGFKEIIK_00239 1.63e-168 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
FGFKEIIK_00240 2.68e-137 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FGFKEIIK_00241 1.16e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
FGFKEIIK_00242 1.16e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FGFKEIIK_00243 9.96e-85 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
FGFKEIIK_00244 2.18e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGFKEIIK_00245 1.21e-69 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
FGFKEIIK_00246 5.77e-81 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
FGFKEIIK_00247 7.55e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGFKEIIK_00248 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
FGFKEIIK_00249 5.03e-192 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FGFKEIIK_00250 9.86e-202 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGFKEIIK_00251 5.04e-29 - - - I - - - Alpha/beta hydrolase family
FGFKEIIK_00252 2.87e-47 yugF - - I - - - carboxylic ester hydrolase activity
FGFKEIIK_00253 7.29e-61 - - - K ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
FGFKEIIK_00254 1.27e-135 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
FGFKEIIK_00255 9.87e-12 - - - - - - - -
FGFKEIIK_00256 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
FGFKEIIK_00257 1.23e-101 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
FGFKEIIK_00258 7.69e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
FGFKEIIK_00259 3.24e-151 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
FGFKEIIK_00260 1.15e-47 ykuJ - - S - - - protein conserved in bacteria
FGFKEIIK_00261 3.17e-231 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGFKEIIK_00262 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
FGFKEIIK_00263 7.82e-111 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
FGFKEIIK_00264 1.29e-64 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
FGFKEIIK_00265 2.73e-84 - - - S - - - oxidoreductase
FGFKEIIK_00266 1.83e-74 - - - S - - - oxidoreductase
FGFKEIIK_00267 3.82e-295 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
FGFKEIIK_00268 2.5e-90 - - - M - - - Pfam SNARE associated Golgi protein
FGFKEIIK_00269 2.58e-131 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
FGFKEIIK_00272 1.44e-268 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
FGFKEIIK_00275 3.44e-22 - - - S - - - Protein of unknown function (DUF2969)
FGFKEIIK_00276 4.29e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
FGFKEIIK_00277 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FGFKEIIK_00278 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FGFKEIIK_00279 1.49e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FGFKEIIK_00280 1.1e-20 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
FGFKEIIK_00281 5.22e-41 - - - S - - - Domain of unknown function (DUF1912)
FGFKEIIK_00282 8.67e-228 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
FGFKEIIK_00283 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
FGFKEIIK_00284 1.93e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
FGFKEIIK_00285 5.14e-287 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FGFKEIIK_00286 4.94e-29 - - - - - - - -
FGFKEIIK_00287 7.02e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FGFKEIIK_00288 5.15e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FGFKEIIK_00289 3.13e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
FGFKEIIK_00290 1.76e-297 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
FGFKEIIK_00291 3.81e-35 - - - K - - - hmm pf08876
FGFKEIIK_00292 1.01e-151 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
FGFKEIIK_00293 9.03e-29 - - - S - - - Protein of unknown function (DUF3114)
FGFKEIIK_00294 6.47e-209 - - - S - - - Protein of unknown function (DUF3114)
FGFKEIIK_00295 1.12e-217 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FGFKEIIK_00296 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGFKEIIK_00297 5.47e-29 - - - - - - - -
FGFKEIIK_00298 0.0 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
FGFKEIIK_00299 2.09e-244 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
FGFKEIIK_00300 1.95e-14 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
FGFKEIIK_00301 3e-59 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
FGFKEIIK_00302 9.15e-10 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
FGFKEIIK_00304 2.99e-151 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FGFKEIIK_00305 1.47e-41 - - - - - - - -
FGFKEIIK_00306 8.64e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
FGFKEIIK_00307 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGFKEIIK_00308 9.21e-244 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
FGFKEIIK_00309 1.5e-231 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
FGFKEIIK_00310 2.38e-224 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
FGFKEIIK_00311 6.57e-195 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
FGFKEIIK_00312 3.96e-137 - - - J ko:K09962 - ko00000 protein conserved in bacteria
FGFKEIIK_00313 9.49e-317 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGFKEIIK_00314 2.16e-57 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
FGFKEIIK_00315 1.29e-24 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 alanine dehydrogenase activity
FGFKEIIK_00316 1.5e-279 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
FGFKEIIK_00317 3.68e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
FGFKEIIK_00318 8.88e-147 - - - S - - - VIT family
FGFKEIIK_00319 4.31e-182 - - - F - - - Phosphorylase superfamily
FGFKEIIK_00321 5.22e-37 XK27_00085 - - K ko:K07729 - ko00000,ko03000 Transcriptional
FGFKEIIK_00322 6.51e-249 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
FGFKEIIK_00323 1.79e-157 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
FGFKEIIK_00324 8.21e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
FGFKEIIK_00325 2.67e-278 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
FGFKEIIK_00326 4.15e-170 rr02 - - KT - - - response regulator
FGFKEIIK_00327 8.65e-293 hk02 - - T - - - signal transduction protein with a C-terminal ATPase domain
FGFKEIIK_00328 7.37e-158 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FGFKEIIK_00329 4.12e-253 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FGFKEIIK_00330 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_00331 0.0 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_00333 0.0 - - - M - - - the current gene model (or a revised gene model) may contain a
FGFKEIIK_00334 3.02e-59 - - - M - - - YSIRK type signal peptide
FGFKEIIK_00335 2.72e-126 - - - S - - - MucBP domain
FGFKEIIK_00338 5.72e-149 hrtB - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
FGFKEIIK_00339 1.31e-155 - - - L - - - Transposase
FGFKEIIK_00340 1.04e-210 - - - L ko:K07497 - ko00000 integrase core domain
FGFKEIIK_00341 5.19e-61 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_00342 1.62e-152 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_00343 1.25e-23 - - - L - - - Integrase core domain
FGFKEIIK_00344 8.12e-243 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_00345 2.46e-69 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
FGFKEIIK_00346 3.14e-101 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGFKEIIK_00347 4.71e-37 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 efflux transmembrane transporter activity
FGFKEIIK_00348 2.27e-46 - - - V ko:K02004 - ko00000,ko00002,ko02000 efflux transmembrane transporter activity
FGFKEIIK_00349 2.28e-23 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
FGFKEIIK_00350 2.69e-49 yknX - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGFKEIIK_00351 2.61e-34 yknX - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGFKEIIK_00352 2.11e-171 - - - S - - - Putative SAM-dependent methyltransferase
FGFKEIIK_00353 1.8e-308 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_00354 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
FGFKEIIK_00355 9.61e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
FGFKEIIK_00356 8.28e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
FGFKEIIK_00357 2.02e-288 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
FGFKEIIK_00358 6.68e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FGFKEIIK_00359 1.71e-208 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
FGFKEIIK_00360 6.92e-101 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FGFKEIIK_00361 1.21e-215 lysR - - K - - - transcriptional regulator (lysR family)
FGFKEIIK_00366 4.58e-156 - - - L - - - Transposase
FGFKEIIK_00367 1.53e-212 - - - L ko:K07497 - ko00000 integrase core domain
FGFKEIIK_00368 1.5e-180 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGFKEIIK_00369 1.02e-177 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
FGFKEIIK_00370 6.05e-93 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
FGFKEIIK_00371 6.07e-33 - 2.7.1.208, 2.7.1.211 - G ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGFKEIIK_00373 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
FGFKEIIK_00374 1.42e-52 ynzC - - S - - - UPF0291 protein
FGFKEIIK_00375 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
FGFKEIIK_00376 2.48e-226 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
FGFKEIIK_00377 2.41e-79 - - - S - - - membrane
FGFKEIIK_00378 1.54e-80 - - - - - - - -
FGFKEIIK_00379 1.94e-34 - - - - - - - -
FGFKEIIK_00380 1.99e-69 - - - - - - - -
FGFKEIIK_00381 1.98e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
FGFKEIIK_00382 4.96e-116 yjbB - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
FGFKEIIK_00383 3.41e-192 XK27_04800 - - S - - - Sucrose-6F-phosphate phosphohydrolase
FGFKEIIK_00384 7.94e-141 mur1 - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 mannosyl-glycoprotein
FGFKEIIK_00385 3.22e-71 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
FGFKEIIK_00386 1.39e-297 amt - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter
FGFKEIIK_00387 1.46e-205 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FGFKEIIK_00388 2.84e-73 yabA - - L - - - Involved in initiation control of chromosome replication
FGFKEIIK_00389 8.56e-179 yaaT - - S - - - stage 0 sporulation protein
FGFKEIIK_00390 5.52e-207 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
FGFKEIIK_00391 5.91e-143 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FGFKEIIK_00392 6.58e-175 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FGFKEIIK_00393 7.86e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGFKEIIK_00394 3.51e-293 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
FGFKEIIK_00395 6.23e-97 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
FGFKEIIK_00396 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGFKEIIK_00397 9.48e-204 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGFKEIIK_00398 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGFKEIIK_00399 3.66e-115 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGFKEIIK_00400 1.78e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase F(0) sector subunit b
FGFKEIIK_00401 4.44e-160 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
FGFKEIIK_00402 5.88e-23 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGFKEIIK_00403 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FGFKEIIK_00404 7.34e-63 - 2.3.1.128, 5.2.1.8 - J ko:K03768,ko:K03790 - ko00000,ko01000,ko03009,ko03110 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGFKEIIK_00405 1.88e-139 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FGFKEIIK_00406 3.61e-17 coiA - - S ko:K06198 - ko00000 Competence protein
FGFKEIIK_00408 1.32e-195 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
FGFKEIIK_00409 1.5e-197 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
FGFKEIIK_00410 2.09e-303 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
FGFKEIIK_00411 2.44e-191 icaB - - G - - - deacetylase
FGFKEIIK_00412 3.91e-268 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
FGFKEIIK_00413 2.67e-166 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
FGFKEIIK_00414 4.21e-285 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FGFKEIIK_00415 5.78e-245 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGFKEIIK_00416 1.73e-291 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
FGFKEIIK_00417 4.68e-189 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
FGFKEIIK_00418 5.09e-126 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
FGFKEIIK_00419 9.52e-45 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
FGFKEIIK_00420 1.85e-241 - - - M - - - GBS Bsp-like repeat
FGFKEIIK_00421 1.67e-29 - - - M - - - GBS Bsp-like repeat
FGFKEIIK_00422 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGFKEIIK_00423 4.05e-224 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
FGFKEIIK_00424 1.38e-163 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
FGFKEIIK_00425 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
FGFKEIIK_00426 6.15e-234 coiA - - S ko:K06198 - ko00000 Competence protein
FGFKEIIK_00427 2.54e-211 - - - K - - - transcriptional regulator (lysR family)
FGFKEIIK_00428 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGFKEIIK_00432 4.56e-244 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
FGFKEIIK_00433 3.19e-90 sip - - M - - - LysM domain protein
FGFKEIIK_00434 7.35e-190 usp 3.5.1.104, 3.5.1.28 CBM50 S ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409 ko05133,map05133 ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000 pathogenesis
FGFKEIIK_00435 1.35e-46 yozE - - S - - - Belongs to the UPF0346 family
FGFKEIIK_00436 1.37e-205 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
FGFKEIIK_00437 3.91e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FGFKEIIK_00438 1.38e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
FGFKEIIK_00439 1.53e-100 sptS - - T - - - Histidine kinase
FGFKEIIK_00440 2.1e-24 - - - K - - - Acetyltransferase (GNAT) family
FGFKEIIK_00441 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
FGFKEIIK_00442 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
FGFKEIIK_00443 4.4e-101 - - - K - - - DNA-binding transcription factor activity
FGFKEIIK_00444 3.88e-92 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
FGFKEIIK_00445 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
FGFKEIIK_00446 7.62e-271 nadR - - H - - - adenylyltransferase
FGFKEIIK_00447 9.06e-181 - - - F - - - AdP-ribose pyrophosphatase
FGFKEIIK_00448 1.12e-27 - - - S - - - Short repeat of unknown function (DUF308)
FGFKEIIK_00449 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
FGFKEIIK_00450 6.49e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FGFKEIIK_00451 4.46e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
FGFKEIIK_00452 2.26e-117 - - - S - - - EDD domain protein, DegV family
FGFKEIIK_00453 3.89e-84 WQ51_03320 - - S - - - cog cog4835
FGFKEIIK_00454 2.07e-172 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGFKEIIK_00455 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
FGFKEIIK_00456 1.99e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
FGFKEIIK_00457 1.13e-37 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
FGFKEIIK_00458 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
FGFKEIIK_00459 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
FGFKEIIK_00460 1.48e-290 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGFKEIIK_00461 1.8e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
FGFKEIIK_00463 1.32e-310 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
FGFKEIIK_00464 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGFKEIIK_00465 9.18e-47 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FGFKEIIK_00466 4.81e-168 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FGFKEIIK_00467 3.01e-64 - 2.7.1.202 - GT ko:K02768,ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
FGFKEIIK_00468 4.7e-70 - 2.7.1.202 - GT ko:K02768,ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
FGFKEIIK_00469 4.36e-210 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
FGFKEIIK_00470 1.37e-165 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
FGFKEIIK_00471 8.72e-111 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_00472 7.33e-310 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
FGFKEIIK_00473 9.38e-84 - - - L ko:K07498 - ko00000 Transposase
FGFKEIIK_00474 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FGFKEIIK_00475 9.33e-177 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
FGFKEIIK_00476 2.95e-205 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FGFKEIIK_00477 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
FGFKEIIK_00478 1.19e-93 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FGFKEIIK_00479 6.1e-88 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FGFKEIIK_00480 2.6e-297 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FGFKEIIK_00481 8.26e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
FGFKEIIK_00482 3.32e-211 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
FGFKEIIK_00483 1.31e-220 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
FGFKEIIK_00484 2.12e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGFKEIIK_00485 1.88e-224 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGFKEIIK_00486 2.67e-96 XK27_02735 - - K - - - Transcriptional regulator, MarR family
FGFKEIIK_00487 4.99e-180 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
FGFKEIIK_00488 1.77e-150 - - - S - - - Haloacid dehalogenase-like hydrolase
FGFKEIIK_00489 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
FGFKEIIK_00490 9.23e-246 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
FGFKEIIK_00491 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGFKEIIK_00492 3.96e-179 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
FGFKEIIK_00493 4.01e-132 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
FGFKEIIK_00494 9.03e-141 - - - S - - - Domain of unknown function (DUF1803)
FGFKEIIK_00495 9.95e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
FGFKEIIK_00503 1.18e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FGFKEIIK_00504 1.91e-158 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
FGFKEIIK_00505 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FGFKEIIK_00506 1.91e-143 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
FGFKEIIK_00507 6e-215 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
FGFKEIIK_00508 1.52e-57 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
FGFKEIIK_00509 9.82e-92 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
FGFKEIIK_00510 6.53e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
FGFKEIIK_00511 3.96e-177 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
FGFKEIIK_00512 7.76e-183 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
FGFKEIIK_00513 8.19e-190 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
FGFKEIIK_00514 2.77e-271 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
FGFKEIIK_00515 4.33e-62 ylbG - - S - - - UPF0298 protein
FGFKEIIK_00516 1.36e-96 ylbF - - S - - - Belongs to the UPF0342 family
FGFKEIIK_00517 2.64e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FGFKEIIK_00518 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FGFKEIIK_00519 5.84e-13 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
FGFKEIIK_00520 5.65e-286 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
FGFKEIIK_00521 1.76e-258 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
FGFKEIIK_00522 7.42e-114 pacL - - P - - - cation transport ATPase
FGFKEIIK_00523 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
FGFKEIIK_00524 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGFKEIIK_00525 5.54e-273 femA 2.3.2.17 - V ko:K11694 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
FGFKEIIK_00526 2.68e-49 - 3.2.2.10 - L ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
FGFKEIIK_00527 1.44e-29 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
FGFKEIIK_00528 9.81e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGFKEIIK_00529 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGFKEIIK_00530 2.19e-56 ylxQ - - J - - - ribosomal protein
FGFKEIIK_00531 6.68e-64 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
FGFKEIIK_00532 2.28e-270 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
FGFKEIIK_00533 3.06e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
FGFKEIIK_00534 1.29e-280 brpA - - K - - - Transcriptional
FGFKEIIK_00535 6.67e-120 - - - M - - - Acetyltransferase GNAT Family
FGFKEIIK_00536 1.54e-101 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
FGFKEIIK_00537 5.45e-315 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
FGFKEIIK_00538 1.46e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
FGFKEIIK_00539 1.84e-181 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
FGFKEIIK_00540 3.98e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
FGFKEIIK_00541 2.08e-162 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
FGFKEIIK_00542 8.21e-215 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
FGFKEIIK_00543 1.52e-81 manO - - S - - - protein conserved in bacteria
FGFKEIIK_00544 2.31e-306 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGFKEIIK_00545 1.92e-38 - - - L ko:K07483 - ko00000 transposase activity
FGFKEIIK_00546 1.74e-30 - - - L - - - Transposase
FGFKEIIK_00547 1.13e-66 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_00548 3.94e-35 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_00549 1.99e-45 - - - - - - - -
FGFKEIIK_00551 5.05e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
FGFKEIIK_00552 1.26e-212 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
FGFKEIIK_00553 4.48e-277 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
FGFKEIIK_00554 1.74e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FGFKEIIK_00555 0.0 covS - - T - - - Histidine kinase
FGFKEIIK_00556 2.69e-158 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FGFKEIIK_00557 1.14e-118 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
FGFKEIIK_00558 1.5e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
FGFKEIIK_00559 1.28e-308 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
FGFKEIIK_00560 1.98e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
FGFKEIIK_00561 4.58e-15 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 L-ascorbate 6-phosphate lactonase
FGFKEIIK_00562 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FGFKEIIK_00563 3.54e-191 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
FGFKEIIK_00564 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
FGFKEIIK_00565 5.41e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
FGFKEIIK_00566 5.95e-202 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
FGFKEIIK_00567 7.28e-268 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FGFKEIIK_00568 1.25e-143 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_00569 2.17e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGFKEIIK_00570 1.96e-82 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
FGFKEIIK_00571 1.48e-82 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
FGFKEIIK_00572 6.08e-112 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
FGFKEIIK_00573 1.26e-212 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
FGFKEIIK_00574 2.6e-196 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
FGFKEIIK_00575 7.28e-268 - - - EGP - - - Transmembrane secretion effector
FGFKEIIK_00576 0.0 - - - F - - - NUDIX domain
FGFKEIIK_00577 0.0 - - - Q - - - Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FGFKEIIK_00578 3.69e-196 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
FGFKEIIK_00579 4.48e-170 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
FGFKEIIK_00580 8.28e-177 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
FGFKEIIK_00581 5e-227 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
FGFKEIIK_00582 3.46e-204 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
FGFKEIIK_00583 4.71e-142 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FGFKEIIK_00584 1.83e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
FGFKEIIK_00585 2.74e-101 ureE - - O ko:K03187 - ko00000 enzyme active site formation
FGFKEIIK_00586 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
FGFKEIIK_00587 3.78e-72 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
FGFKEIIK_00588 1.02e-61 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
FGFKEIIK_00589 6.21e-124 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
FGFKEIIK_00590 8.86e-69 - - - S - - - Domain of unknown function (DUF4173)
FGFKEIIK_00591 3.67e-62 yhaI - - L - - - Membrane
FGFKEIIK_00592 1.34e-89 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
FGFKEIIK_00593 2.72e-36 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
FGFKEIIK_00594 4.79e-47 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
FGFKEIIK_00595 3.47e-78 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
FGFKEIIK_00596 4.54e-47 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
FGFKEIIK_00597 5.6e-45 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
FGFKEIIK_00598 1.03e-206 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
FGFKEIIK_00599 2.31e-148 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
FGFKEIIK_00600 3.25e-116 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FGFKEIIK_00601 3.83e-125 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FGFKEIIK_00602 1.1e-311 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
FGFKEIIK_00603 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
FGFKEIIK_00604 7.39e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
FGFKEIIK_00605 1.82e-178 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
FGFKEIIK_00606 7.56e-129 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FGFKEIIK_00607 5.32e-153 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FGFKEIIK_00608 3.26e-172 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
FGFKEIIK_00609 1.74e-111 ykuL - - S - - - CBS domain
FGFKEIIK_00610 7.82e-128 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
FGFKEIIK_00611 1.64e-236 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGFKEIIK_00612 1.89e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
FGFKEIIK_00613 5.74e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
FGFKEIIK_00614 2.12e-119 - - - K - - - transcriptional regulator
FGFKEIIK_00615 1.42e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
FGFKEIIK_00618 2e-144 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
FGFKEIIK_00619 1.86e-114 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
FGFKEIIK_00620 6.83e-169 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGFKEIIK_00621 3.32e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
FGFKEIIK_00622 1.52e-211 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FGFKEIIK_00623 3.41e-78 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_00624 1.17e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FGFKEIIK_00625 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FGFKEIIK_00626 1.24e-104 XK27_09675 - - K ko:K07105 - ko00000 -acetyltransferase
FGFKEIIK_00627 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
FGFKEIIK_00628 3.69e-27 XK27_11680 - - - - - - -
FGFKEIIK_00629 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
FGFKEIIK_00630 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
FGFKEIIK_00631 6.16e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
FGFKEIIK_00632 3.39e-67 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
FGFKEIIK_00633 8.82e-124 ypsA - - S - - - Belongs to the UPF0398 family
FGFKEIIK_00634 1.72e-141 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FGFKEIIK_00635 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
FGFKEIIK_00636 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
FGFKEIIK_00637 1.37e-99 yhaI - - L - - - Membrane
FGFKEIIK_00638 6.15e-195 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
FGFKEIIK_00639 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FGFKEIIK_00640 2.7e-84 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
FGFKEIIK_00641 3.44e-83 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
FGFKEIIK_00642 7.76e-30 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
FGFKEIIK_00643 7.03e-53 napB - - K - - - transcriptional
FGFKEIIK_00644 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
FGFKEIIK_00645 6.57e-176 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
FGFKEIIK_00646 1.89e-47 cof - - Q - - - phosphatase activity
FGFKEIIK_00647 6.76e-73 cof - - Q - - - phosphatase activity
FGFKEIIK_00648 1.17e-110 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
FGFKEIIK_00649 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
FGFKEIIK_00650 6.28e-35 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
FGFKEIIK_00651 4.01e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
FGFKEIIK_00652 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
FGFKEIIK_00653 1.17e-212 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
FGFKEIIK_00654 5.62e-75 WQ51_06355 - - S - - - TM2 domain
FGFKEIIK_00655 1.16e-57 - - - - - - - -
FGFKEIIK_00658 4.56e-40 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_00659 2.46e-24 - - - L ko:K07483 - ko00000 transposase activity
FGFKEIIK_00660 3.93e-49 - - - L - - - Transposase
FGFKEIIK_00661 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
FGFKEIIK_00662 6.35e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGFKEIIK_00663 8.63e-183 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_00664 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
FGFKEIIK_00665 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
FGFKEIIK_00666 2.21e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
FGFKEIIK_00667 1.83e-187 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
FGFKEIIK_00668 1.76e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGFKEIIK_00669 9.27e-66 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
FGFKEIIK_00670 3.92e-163 yeeN - - K - - - transcriptional regulatory protein
FGFKEIIK_00671 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
FGFKEIIK_00672 2e-201 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
FGFKEIIK_00673 1.13e-136 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
FGFKEIIK_00674 1.42e-197 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
FGFKEIIK_00675 3.56e-86 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
FGFKEIIK_00676 1.19e-207 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
FGFKEIIK_00677 1.73e-163 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_00678 8.76e-176 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FGFKEIIK_00679 1.28e-94 adcR - - K - - - transcriptional
FGFKEIIK_00680 1.03e-284 - - - EGP - - - Major facilitator Superfamily
FGFKEIIK_00681 2.41e-234 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGFKEIIK_00682 3.85e-201 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FGFKEIIK_00683 1.32e-29 - - - - - - - -
FGFKEIIK_00684 2.62e-85 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FGFKEIIK_00685 1.75e-78 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FGFKEIIK_00686 9.86e-54 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FGFKEIIK_00687 1.53e-82 - - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FGFKEIIK_00688 1.15e-43 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FGFKEIIK_00689 9.63e-38 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FGFKEIIK_00690 3.42e-50 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGFKEIIK_00691 4.52e-54 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGFKEIIK_00692 4.03e-14 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGFKEIIK_00693 9e-36 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGFKEIIK_00694 1.34e-178 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
FGFKEIIK_00695 5.77e-13 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
FGFKEIIK_00696 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
FGFKEIIK_00697 2.78e-98 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
FGFKEIIK_00698 2.95e-303 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGFKEIIK_00699 5.93e-299 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
FGFKEIIK_00700 1.82e-184 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
FGFKEIIK_00701 1.25e-248 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
FGFKEIIK_00702 4.29e-174 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
FGFKEIIK_00703 1.24e-195 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
FGFKEIIK_00704 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
FGFKEIIK_00705 3e-168 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
FGFKEIIK_00707 7.59e-10 - - - D - - - nuclear chromosome segregation
FGFKEIIK_00708 8.47e-126 - - - V - - - VanZ like family
FGFKEIIK_00709 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGFKEIIK_00710 2.59e-258 XK27_00055 - - P - - - Major Facilitator
FGFKEIIK_00711 4e-147 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
FGFKEIIK_00712 2.96e-145 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FGFKEIIK_00713 9.52e-303 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FGFKEIIK_00714 7.68e-65 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
FGFKEIIK_00715 5.22e-69 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
FGFKEIIK_00716 1.69e-32 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
FGFKEIIK_00717 3.09e-13 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
FGFKEIIK_00718 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FGFKEIIK_00719 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGFKEIIK_00720 3.73e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
FGFKEIIK_00721 0.0 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
FGFKEIIK_00722 7.42e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
FGFKEIIK_00723 4.45e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
FGFKEIIK_00724 1.08e-106 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
FGFKEIIK_00725 3.04e-110 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
FGFKEIIK_00726 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
FGFKEIIK_00727 3.71e-119 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
FGFKEIIK_00728 6.47e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FGFKEIIK_00729 5.87e-192 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
FGFKEIIK_00730 7.24e-102 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
FGFKEIIK_00731 1.22e-113 - - - - - - - -
FGFKEIIK_00732 1.13e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
FGFKEIIK_00733 4.51e-66 amd - - E - - - Peptidase dimerisation domain
FGFKEIIK_00737 9.65e-96 hmpT - - S - - - cog cog4720
FGFKEIIK_00738 3.02e-176 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
FGFKEIIK_00739 7.15e-177 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
FGFKEIIK_00740 4.64e-253 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FGFKEIIK_00741 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
FGFKEIIK_00742 2.58e-101 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGFKEIIK_00743 2.19e-250 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
FGFKEIIK_00744 7.28e-132 acmA 3.2.1.17 - NU ko:K01185,ko:K02395 - ko00000,ko01000,ko02035 amidase activity
FGFKEIIK_00745 7.71e-185 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
FGFKEIIK_00746 1.93e-49 ais - - G - - - alpha-ribazole phosphatase activity
FGFKEIIK_00747 1.6e-307 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
FGFKEIIK_00748 1.76e-52 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
FGFKEIIK_00749 3.89e-285 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
FGFKEIIK_00750 3.78e-117 - - - L ko:K07498 - ko00000 Transposase
FGFKEIIK_00751 4.04e-95 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
FGFKEIIK_00753 1.37e-219 - - - - - - - -
FGFKEIIK_00754 1.43e-52 - - - S - - - Helix-turn-helix domain
FGFKEIIK_00755 3.54e-132 int - - L - - - Belongs to the 'phage' integrase family
FGFKEIIK_00756 1.88e-63 int - - L - - - Belongs to the 'phage' integrase family
FGFKEIIK_00757 5.31e-120 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Divergent AAA domain protein
FGFKEIIK_00758 3.69e-236 - - - EGP - - - Major Facilitator Superfamily
FGFKEIIK_00759 8.01e-295 spaC2 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
FGFKEIIK_00760 0.0 - - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
FGFKEIIK_00762 5.98e-47 - - - K - - - sequence-specific DNA binding
FGFKEIIK_00763 1.8e-308 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_00764 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
FGFKEIIK_00765 7.02e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FGFKEIIK_00766 4e-234 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FGFKEIIK_00767 1.22e-42 - - - K - - - helix-turn-helix
FGFKEIIK_00768 1.29e-05 - - - K - - - PFAM helix-turn-helix domain protein
FGFKEIIK_00769 1.1e-199 yitS - - S - - - DegV family
FGFKEIIK_00770 1.62e-111 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
FGFKEIIK_00771 1.23e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGFKEIIK_00774 2.1e-90 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FGFKEIIK_00775 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
FGFKEIIK_00776 7.75e-145 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
FGFKEIIK_00777 1.9e-185 - - - S - - - SseB protein N-terminal domain
FGFKEIIK_00778 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
FGFKEIIK_00779 3.26e-294 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
FGFKEIIK_00780 3.96e-40 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
FGFKEIIK_00781 1.71e-193 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
FGFKEIIK_00782 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
FGFKEIIK_00783 2.83e-99 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
FGFKEIIK_00784 3.55e-109 - - - S - - - Putative small multi-drug export protein
FGFKEIIK_00785 1.73e-232 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGFKEIIK_00786 2.48e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
FGFKEIIK_00789 1.28e-102 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
FGFKEIIK_00790 1.88e-99 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 carboxypeptidase activity
FGFKEIIK_00792 1.2e-54 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_00793 3.79e-116 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_00794 1.29e-106 XK27_03570 - - S ko:K19784 - ko00000 reductase
FGFKEIIK_00795 1.44e-72 badR - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
FGFKEIIK_00796 4.88e-49 XK27_02060 - - S - - - Transglycosylase associated protein
FGFKEIIK_00797 4.87e-299 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
FGFKEIIK_00798 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FGFKEIIK_00812 1.27e-86 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
FGFKEIIK_00813 2.51e-261 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGFKEIIK_00814 2.06e-296 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
FGFKEIIK_00815 1.89e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
FGFKEIIK_00816 4.38e-134 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
FGFKEIIK_00818 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGFKEIIK_00820 2.17e-81 - - - KT - - - phosphorelay signal transduction system
FGFKEIIK_00821 1.06e-43 - - - S - - - Protein of unknown function (DUF3021)
FGFKEIIK_00822 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FGFKEIIK_00823 5.42e-75 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
FGFKEIIK_00824 1.36e-90 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
FGFKEIIK_00825 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
FGFKEIIK_00826 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGFKEIIK_00827 1.69e-181 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
FGFKEIIK_00828 1.03e-261 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FGFKEIIK_00829 2.66e-99 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGFKEIIK_00830 1.65e-305 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
FGFKEIIK_00831 6.22e-207 - - - S - - - CHAP domain
FGFKEIIK_00832 1.37e-41 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_00833 4.39e-66 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_00834 1.7e-117 - - - L ko:K07483 - ko00000 transposase activity
FGFKEIIK_00835 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
FGFKEIIK_00836 6.85e-132 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FGFKEIIK_00837 5.98e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
FGFKEIIK_00838 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FGFKEIIK_00839 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGFKEIIK_00840 1.75e-166 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
FGFKEIIK_00841 3.89e-46 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGFKEIIK_00842 2.58e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FGFKEIIK_00843 5.05e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
FGFKEIIK_00844 1.06e-278 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
FGFKEIIK_00845 2.75e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGFKEIIK_00846 3.54e-175 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
FGFKEIIK_00847 1.34e-115 mreD - - M ko:K03571 - ko00000,ko03036 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FGFKEIIK_00848 4.24e-183 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
FGFKEIIK_00867 8e-106 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_00868 7.11e-39 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_00869 1.39e-119 - - - L - - - Transposase
FGFKEIIK_00870 1.3e-209 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_00871 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGFKEIIK_00872 2.22e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
FGFKEIIK_00873 3.77e-307 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
FGFKEIIK_00874 2.66e-307 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
FGFKEIIK_00875 1.94e-05 - - - - - - - -
FGFKEIIK_00876 1.16e-80 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
FGFKEIIK_00877 3.77e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
FGFKEIIK_00878 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FGFKEIIK_00879 4.43e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
FGFKEIIK_00880 8.98e-111 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FGFKEIIK_00881 5.8e-116 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FGFKEIIK_00882 1.4e-40 yyzM - - S - - - Protein conserved in bacteria
FGFKEIIK_00883 1.29e-258 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FGFKEIIK_00884 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGFKEIIK_00885 7.94e-173 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
FGFKEIIK_00886 2.58e-261 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
FGFKEIIK_00887 1.79e-111 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FGFKEIIK_00888 3.66e-155 yveI - - S - - - Psort location CytoplasmicMembrane, score
FGFKEIIK_00892 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
FGFKEIIK_00893 0.0 ykpA - - S - - - abc transporter atp-binding protein
FGFKEIIK_00894 9.73e-196 XK27_10395 - - S - - - membrane
FGFKEIIK_00895 1.66e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
FGFKEIIK_00896 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
FGFKEIIK_00897 9.13e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FGFKEIIK_00898 5.21e-61 yaaA - - S - - - S4 domain protein YaaA
FGFKEIIK_00899 1.06e-299 albE - - S - - - Peptidase M16
FGFKEIIK_00900 1.88e-309 ymfH - - S - - - Peptidase M16
FGFKEIIK_00901 8.84e-185 ymfM - - S ko:K15539 - ko00000 sequence-specific DNA binding
FGFKEIIK_00902 7.67e-118 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FGFKEIIK_00903 4.68e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FGFKEIIK_00904 2.6e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FGFKEIIK_00905 1.73e-176 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FGFKEIIK_00906 1.37e-122 lytE - - M - - - LysM domain protein
FGFKEIIK_00907 1.41e-125 isaA - - M - - - Immunodominant staphylococcal antigen A
FGFKEIIK_00908 0.0 - - - S - - - Bacterial membrane protein, YfhO
FGFKEIIK_00909 9.38e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FGFKEIIK_00910 1.46e-101 - - - F - - - NUDIX domain
FGFKEIIK_00911 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
FGFKEIIK_00912 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
FGFKEIIK_00913 1.24e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
FGFKEIIK_00914 1.29e-312 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
FGFKEIIK_00915 3.05e-63 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
FGFKEIIK_00916 5.92e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGFKEIIK_00917 2.05e-09 - - - - - - - -
FGFKEIIK_00918 7.97e-73 XK27_04840 - - M ko:K08987 - ko00000 Membrane
FGFKEIIK_00919 3.98e-124 XK27_06935 - - K - - - transcriptional regulator
FGFKEIIK_00920 5.13e-270 XK27_06930 - - V ko:K01421 - ko00000 domain protein
FGFKEIIK_00921 7.22e-121 - - - S - - - Putative adhesin
FGFKEIIK_00922 1.58e-28 - - - S - - - Protein of unknown function (DUF1700)
FGFKEIIK_00923 1.91e-10 - - - S - - - Protein of unknown function (DUF1700)
FGFKEIIK_00924 4.32e-33 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
FGFKEIIK_00925 1.3e-26 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
FGFKEIIK_00926 7.54e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_00927 2.9e-18 XK27_06885 - - L - - - hydrolase
FGFKEIIK_00928 4.09e-123 XK27_06885 - - L - - - hydrolase
FGFKEIIK_00929 5.78e-35 - - - K - - - CsbD-like
FGFKEIIK_00930 4.11e-104 - - - S - - - Asp23 family, cell envelope-related function
FGFKEIIK_00931 7.53e-33 - - - S - - - Small integral membrane protein
FGFKEIIK_00932 1.88e-131 - - - - - - - -
FGFKEIIK_00933 7.98e-45 ytgB - - S - - - Membrane
FGFKEIIK_00935 8.43e-124 - - - S - - - Hydrophobic domain protein
FGFKEIIK_00936 1.03e-27 yegS 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 lipid kinase activity
FGFKEIIK_00938 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
FGFKEIIK_00939 4.33e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
FGFKEIIK_00940 2.66e-44 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
FGFKEIIK_00941 4.02e-80 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
FGFKEIIK_00942 6.96e-65 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
FGFKEIIK_00943 6.78e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
FGFKEIIK_00945 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
FGFKEIIK_00946 1.53e-215 XK27_01785 - - S - - - cog cog1284
FGFKEIIK_00947 4.85e-189 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
FGFKEIIK_00948 5.13e-149 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGFKEIIK_00949 1.31e-118 - - - K - - - acetyltransferase
FGFKEIIK_00950 7.68e-20 - - - - - - - -
FGFKEIIK_00951 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
FGFKEIIK_00952 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
FGFKEIIK_00953 2.7e-62 yrzB - - S - - - Belongs to the UPF0473 family
FGFKEIIK_00954 8.4e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FGFKEIIK_00955 3.4e-59 yrzL - - S - - - Belongs to the UPF0297 family
FGFKEIIK_00956 1.73e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
FGFKEIIK_00957 3.74e-303 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
FGFKEIIK_00959 6.11e-278 - - - L - - - Belongs to the 'phage' integrase family
FGFKEIIK_00960 1.95e-26 - - - S - - - Domain of unknown function (DUF3173)
FGFKEIIK_00961 2.81e-137 - - - L - - - Replication initiation factor
FGFKEIIK_00962 2.67e-53 - - - L - - - Replication initiation factor
FGFKEIIK_00963 1.59e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
FGFKEIIK_00964 5.53e-79 - - - K - - - sequence-specific DNA binding
FGFKEIIK_00965 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
FGFKEIIK_00966 1.85e-243 - - - C ko:K06871 - ko00000 Radical SAM
FGFKEIIK_00967 9.82e-21 - - - C ko:K06871 - ko00000 Radical SAM
FGFKEIIK_00969 4.66e-165 Z012_04635 - - K - - - sequence-specific DNA binding
FGFKEIIK_00970 3.79e-16 - - - K - - - Transcriptional activator, Rgg GadR MutR family
FGFKEIIK_00971 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
FGFKEIIK_00972 0.0 - - - KLT - - - serine threonine protein kinase
FGFKEIIK_00973 7.46e-200 - - - K ko:K20373,ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
FGFKEIIK_00975 5.63e-188 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_00976 7.94e-69 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_00977 3.96e-253 - 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Involved in molybdopterin and thiamine biosynthesis, family 2
FGFKEIIK_00978 3.14e-244 - - - EGP - - - Major Facilitator Superfamily
FGFKEIIK_00979 3.91e-109 flaR - - F - - - topology modulation protein
FGFKEIIK_00980 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FGFKEIIK_00981 2.29e-106 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGFKEIIK_00982 2.43e-47 - - - S - - - MORN repeat protein
FGFKEIIK_00983 0.0 XK27_09800 - - I - - - Acyltransferase
FGFKEIIK_00984 1.78e-240 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
FGFKEIIK_00985 7.41e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
FGFKEIIK_00986 7.78e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGFKEIIK_00987 2.13e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
FGFKEIIK_00988 6e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
FGFKEIIK_00989 7.19e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGFKEIIK_00990 1.99e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGFKEIIK_00991 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGFKEIIK_00992 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGFKEIIK_00993 3.58e-93 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGFKEIIK_00994 4.36e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
FGFKEIIK_00995 3.08e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FGFKEIIK_00996 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGFKEIIK_00997 5.67e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FGFKEIIK_00998 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGFKEIIK_00999 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGFKEIIK_01000 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGFKEIIK_01001 1.44e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGFKEIIK_01002 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FGFKEIIK_01003 9.94e-104 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGFKEIIK_01004 2e-32 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
FGFKEIIK_01005 1.03e-85 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
FGFKEIIK_01006 2.12e-293 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
FGFKEIIK_01007 2.61e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
FGFKEIIK_01008 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGFKEIIK_01009 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
FGFKEIIK_01010 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGFKEIIK_01011 1.57e-80 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FGFKEIIK_01012 5.37e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGFKEIIK_01013 2.13e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
FGFKEIIK_01014 3.04e-141 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
FGFKEIIK_01015 5.1e-12 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
FGFKEIIK_01016 2.41e-15 - - - H - - - gamma-glutamylcysteine synthetase
FGFKEIIK_01017 1.16e-79 - - - H - - - gamma-glutamylcysteine synthetase
FGFKEIIK_01018 1.52e-141 - 6.3.2.2 - H ko:K01919,ko:K06048 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 ergothioneine biosynthetic process
FGFKEIIK_01020 2.34e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
FGFKEIIK_01021 2.62e-179 - - - L - - - DNA integration
FGFKEIIK_01022 4.06e-289 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_01023 2.84e-46 - - - - - - - -
FGFKEIIK_01024 9.41e-265 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
FGFKEIIK_01025 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
FGFKEIIK_01026 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
FGFKEIIK_01027 1.8e-175 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
FGFKEIIK_01028 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
FGFKEIIK_01029 1.75e-80 cadC - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
FGFKEIIK_01030 9.73e-62 - - - S - - - Domain of unknown function (DUF4298)
FGFKEIIK_01031 7.64e-113 - - - L - - - Phage integrase family
FGFKEIIK_01032 1.51e-94 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
FGFKEIIK_01033 7.69e-18 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
FGFKEIIK_01035 1.6e-122 ywlG - - S - - - Belongs to the UPF0340 family
FGFKEIIK_01036 1.53e-112 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
FGFKEIIK_01037 2.66e-29 treR - - K ko:K03486,ko:K03710 - ko00000,ko03000 DNA-binding transcription factor activity
FGFKEIIK_01038 3.49e-72 treB 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS System
FGFKEIIK_01039 4.14e-87 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
FGFKEIIK_01040 4.39e-90 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
FGFKEIIK_01041 3.67e-49 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
FGFKEIIK_01042 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
FGFKEIIK_01043 9.31e-84 - 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
FGFKEIIK_01044 1.15e-165 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
FGFKEIIK_01045 1.16e-100 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
FGFKEIIK_01046 5.24e-49 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 hydroxyacid-oxoacid transhydrogenase activity
FGFKEIIK_01047 3.43e-77 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
FGFKEIIK_01048 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
FGFKEIIK_01049 1.12e-287 norN - - V - - - Mate efflux family protein
FGFKEIIK_01050 1.87e-76 asp - - S - - - cog cog1302
FGFKEIIK_01051 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
FGFKEIIK_01052 1.57e-11 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
FGFKEIIK_01053 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
FGFKEIIK_01054 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
FGFKEIIK_01055 2.89e-100 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
FGFKEIIK_01056 2.67e-250 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FGFKEIIK_01057 1.65e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGFKEIIK_01058 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
FGFKEIIK_01059 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGFKEIIK_01060 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGFKEIIK_01061 1.13e-90 - - - S - - - cog cog4699
FGFKEIIK_01062 1.89e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGFKEIIK_01063 1.22e-185 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
FGFKEIIK_01064 2.23e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
FGFKEIIK_01065 1.03e-75 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
FGFKEIIK_01066 9.03e-22 - - - NU - - - Type II secretory pathway pseudopilin
FGFKEIIK_01067 7.93e-94 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
FGFKEIIK_01068 7.17e-17 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
FGFKEIIK_01069 5.86e-227 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
FGFKEIIK_01070 8.04e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGFKEIIK_01071 5.36e-07 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
FGFKEIIK_01072 5.18e-44 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
FGFKEIIK_01073 7.87e-87 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
FGFKEIIK_01075 1.17e-143 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
FGFKEIIK_01076 1.17e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FGFKEIIK_01077 6.4e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
FGFKEIIK_01079 3.48e-73 ytpP - - CO - - - Thioredoxin
FGFKEIIK_01080 5.51e-147 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FGFKEIIK_01081 1.26e-245 yeeE - - S ko:K07112 - ko00000 Sulphur transport
FGFKEIIK_01082 2.25e-49 yeeD - - O ko:K07112 - ko00000 sulfur carrier activity
FGFKEIIK_01083 3.13e-86 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FGFKEIIK_01084 1.7e-117 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
FGFKEIIK_01086 1.41e-202 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
FGFKEIIK_01087 8.85e-85 - - - S ko:K07025 - ko00000 phosphatase activity
FGFKEIIK_01088 9.35e-64 - - - S ko:K07025 - ko00000 glycolate biosynthetic process
FGFKEIIK_01089 6.92e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
FGFKEIIK_01090 1.63e-281 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
FGFKEIIK_01091 2.82e-122 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FGFKEIIK_01092 2.39e-154 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
FGFKEIIK_01093 7.92e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
FGFKEIIK_01094 5.94e-238 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
FGFKEIIK_01095 9.39e-83 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
FGFKEIIK_01096 4.96e-82 nirC_1 - - P - - - Formate nitrite transporter
FGFKEIIK_01097 3.86e-182 XK27_09615 - - C ko:K19784 - ko00000 reductase
FGFKEIIK_01098 4.64e-77 XK27_09615 - - C ko:K19784 - ko00000 reductase
FGFKEIIK_01099 5.98e-100 - - - S - - - reductase
FGFKEIIK_01100 3.06e-27 XK27_09620 - - S - - - FMN reductase (NADPH) activity
FGFKEIIK_01101 7.02e-103 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
FGFKEIIK_01102 6.08e-280 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FGFKEIIK_01103 1.25e-15 - - - S - - - Mitochondrial biogenesis AIM24
FGFKEIIK_01104 2.42e-49 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
FGFKEIIK_01105 1.31e-113 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
FGFKEIIK_01106 3.28e-66 - - - S - - - Protein of unknown function (DUF3397)
FGFKEIIK_01107 1.69e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FGFKEIIK_01108 1.94e-155 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
FGFKEIIK_01109 1.82e-97 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
FGFKEIIK_01110 1.01e-104 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
FGFKEIIK_01111 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGFKEIIK_01112 3.19e-294 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
FGFKEIIK_01113 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
FGFKEIIK_01114 8.28e-73 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
FGFKEIIK_01115 1.8e-180 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FGFKEIIK_01116 7.21e-239 jag - - S ko:K06346 - ko00000 RNA-binding protein
FGFKEIIK_01117 0.0 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_01118 9.33e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
FGFKEIIK_01119 1.37e-45 - - - L ko:K07491 - ko00000 Transposase
FGFKEIIK_01120 3.46e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
FGFKEIIK_01123 1.18e-72 bta 1.8.1.8 - CO ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 cell redox homeostasis
FGFKEIIK_01124 2.59e-13 yneP - - L ko:K07107 - ko00000,ko01000 thioesterase
FGFKEIIK_01125 5.03e-183 - - - S - - - Macro domain protein
FGFKEIIK_01126 5.36e-68 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
FGFKEIIK_01127 1.14e-98 yneT - - S ko:K06929 - ko00000 CoA-binding protein
FGFKEIIK_01128 2.6e-184 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
FGFKEIIK_01129 1.05e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FGFKEIIK_01130 1.06e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
FGFKEIIK_01132 5.32e-209 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FGFKEIIK_01133 2.76e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
FGFKEIIK_01134 2.73e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
FGFKEIIK_01135 4.63e-236 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
FGFKEIIK_01136 4.81e-229 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
FGFKEIIK_01137 2.67e-185 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
FGFKEIIK_01138 4.89e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FGFKEIIK_01139 4.66e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
FGFKEIIK_01140 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGFKEIIK_01141 3.33e-242 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FGFKEIIK_01142 5.68e-143 - - - L - - - Transposase
FGFKEIIK_01143 4.11e-129 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_01144 4.35e-108 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_01145 3.23e-75 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_01146 2.46e-30 - - - L - - - Transposase
FGFKEIIK_01147 6.62e-62 - - - L ko:K07483 - ko00000 transposase activity
FGFKEIIK_01148 4.29e-57 - - - L ko:K07491 - ko00000 Transposase
FGFKEIIK_01149 9.51e-283 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
FGFKEIIK_01150 8.38e-42 - - - - - - - -
FGFKEIIK_01151 1.82e-17 - - - - - - - -
FGFKEIIK_01152 1.08e-113 - - - S - - - Fusaric acid resistance protein-like
FGFKEIIK_01153 1.12e-83 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
FGFKEIIK_01154 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
FGFKEIIK_01155 4.75e-53 sle1 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 CHAP domain protein
FGFKEIIK_01156 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FGFKEIIK_01157 6.45e-45 ykzG - - S - - - Belongs to the UPF0356 family
FGFKEIIK_01158 2.39e-156 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
FGFKEIIK_01159 6.26e-96 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
FGFKEIIK_01160 1.64e-238 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGFKEIIK_01161 7.27e-148 XK27_12120 - - E - - - AzlC protein
FGFKEIIK_01162 3.85e-63 azlD - - E - - - branched-chain amino acid
FGFKEIIK_01163 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
FGFKEIIK_01164 3.19e-146 spi 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
FGFKEIIK_01165 4.7e-206 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGFKEIIK_01166 5.78e-19 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FGFKEIIK_01167 3.39e-121 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
FGFKEIIK_01168 2.58e-69 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FGFKEIIK_01169 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FGFKEIIK_01170 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGFKEIIK_01175 6.75e-293 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
FGFKEIIK_01176 1.39e-50 XK27_05745 - - - - - - -
FGFKEIIK_01177 1.88e-62 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
FGFKEIIK_01178 2.07e-118 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FGFKEIIK_01179 2.03e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGFKEIIK_01181 5.06e-160 - - - S - - - Pfam PF06570
FGFKEIIK_01182 6.01e-218 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
FGFKEIIK_01183 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGFKEIIK_01186 1.13e-74 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
FGFKEIIK_01187 6.03e-55 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
FGFKEIIK_01189 2.5e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
FGFKEIIK_01190 1.43e-109 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
FGFKEIIK_01191 1.22e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGFKEIIK_01192 9.01e-81 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
FGFKEIIK_01193 2.67e-96 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGFKEIIK_01194 7.4e-227 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional
FGFKEIIK_01195 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
FGFKEIIK_01196 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
FGFKEIIK_01197 1.37e-219 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
FGFKEIIK_01198 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
FGFKEIIK_01200 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FGFKEIIK_01201 2.03e-251 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGFKEIIK_01202 1.01e-251 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGFKEIIK_01203 1.75e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
FGFKEIIK_01204 1.16e-244 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGFKEIIK_01205 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FGFKEIIK_01207 3.09e-223 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
FGFKEIIK_01208 0.0 - - - S - - - hydrolases of the HAD superfamily
FGFKEIIK_01209 1.77e-24 yebC - - M - - - Membrane
FGFKEIIK_01210 2.99e-127 yebC - - M - - - Membrane
FGFKEIIK_01211 9.03e-80 - - - KT - - - response to antibiotic
FGFKEIIK_01212 1.31e-98 - - - K - - - LytTr DNA-binding domain
FGFKEIIK_01213 2.47e-155 - - - S - - - membrane
FGFKEIIK_01214 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FGFKEIIK_01215 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
FGFKEIIK_01216 1.22e-161 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
FGFKEIIK_01217 2.59e-172 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_01218 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
FGFKEIIK_01219 1.43e-181 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FGFKEIIK_01220 8.59e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FGFKEIIK_01221 2.06e-31 - - - D - - - nuclear chromosome segregation
FGFKEIIK_01222 1.58e-42 - - - J - - - Protein of unknown function (DUF805)
FGFKEIIK_01225 3.81e-55 - - - - - - - -
FGFKEIIK_01226 2.52e-34 - - - - - - - -
FGFKEIIK_01227 6.56e-84 - - - - - - - -
FGFKEIIK_01228 1.54e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FGFKEIIK_01229 3.89e-62 ftsL - - D - - - cell division protein FtsL
FGFKEIIK_01230 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
FGFKEIIK_01231 8.08e-236 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGFKEIIK_01232 2.26e-303 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
FGFKEIIK_01234 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
FGFKEIIK_01235 4.03e-138 yutD - - J - - - protein conserved in bacteria
FGFKEIIK_01236 9.55e-287 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FGFKEIIK_01237 2.82e-122 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
FGFKEIIK_01239 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_01240 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_01241 4.89e-133 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
FGFKEIIK_01242 0.0 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
FGFKEIIK_01243 5.03e-311 mesE - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 Transport protein ComB
FGFKEIIK_01245 9.46e-298 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
FGFKEIIK_01246 3.68e-172 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
FGFKEIIK_01249 2.55e-33 - - - S - - - Bacteriocin class II with double-glycine leader peptide
FGFKEIIK_01250 0.000703 - - - - - - - -
FGFKEIIK_01254 1.53e-212 - - - L ko:K07497 - ko00000 integrase core domain
FGFKEIIK_01255 4.58e-156 - - - L - - - Transposase
FGFKEIIK_01256 4.64e-159 blpT - - - - - - -
FGFKEIIK_01257 9.35e-36 blpT - - - - - - -
FGFKEIIK_01258 1.31e-63 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
FGFKEIIK_01261 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
FGFKEIIK_01262 7.59e-212 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
FGFKEIIK_01263 2.69e-56 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
FGFKEIIK_01264 6.61e-179 cppA - - E - - - CppA N-terminal
FGFKEIIK_01265 1.97e-233 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
FGFKEIIK_01266 1.02e-151 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_01267 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
FGFKEIIK_01268 1.96e-113 - - - D - - - nuclear chromosome segregation
FGFKEIIK_01269 5.58e-60 hsdS_1 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
FGFKEIIK_01270 9.32e-112 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FGFKEIIK_01271 6.92e-190 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
FGFKEIIK_01272 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
FGFKEIIK_01273 2.53e-264 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGFKEIIK_01275 1.27e-195 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
FGFKEIIK_01276 5.95e-210 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_01277 1.61e-168 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
FGFKEIIK_01278 1.48e-13 - - - S - - - Protein of unknown function (DUF4059)
FGFKEIIK_01279 4.78e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
FGFKEIIK_01280 5.22e-120 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
FGFKEIIK_01281 7.91e-115 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGFKEIIK_01282 7.98e-252 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
FGFKEIIK_01283 1.51e-236 ytqA - - S ko:K07139 - ko00000 radical SAM protein
FGFKEIIK_01284 9e-127 mraW1 - - J - - - (SAM)-dependent
FGFKEIIK_01286 0.0 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
FGFKEIIK_01287 1.06e-184 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
FGFKEIIK_01288 1.17e-303 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
FGFKEIIK_01289 6.98e-202 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGFKEIIK_01292 7.54e-99 XK27_03180 - - T - - - universal stress protein
FGFKEIIK_01293 2.61e-303 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
FGFKEIIK_01294 6.34e-182 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FGFKEIIK_01295 3.02e-130 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
FGFKEIIK_01296 2.31e-197 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
FGFKEIIK_01297 1.96e-125 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGFKEIIK_01298 0.0 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
FGFKEIIK_01299 6.32e-42 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
FGFKEIIK_01300 7.49e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGFKEIIK_01301 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
FGFKEIIK_01302 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGFKEIIK_01303 9.12e-76 - - - - - - - -
FGFKEIIK_01304 3.49e-196 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
FGFKEIIK_01305 1.84e-127 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
FGFKEIIK_01306 2.78e-275 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
FGFKEIIK_01307 1.59e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
FGFKEIIK_01308 5.51e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGFKEIIK_01309 2.01e-139 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
FGFKEIIK_01310 9.81e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FGFKEIIK_01311 2.78e-179 XK27_06665 - - Q - - - Methyltransferase domain protein
FGFKEIIK_01312 4.36e-263 ylbM - - S - - - Belongs to the UPF0348 family
FGFKEIIK_01313 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
FGFKEIIK_01314 3.82e-140 - - - - - - - -
FGFKEIIK_01315 1.93e-67 - - - S - - - CD20-like family
FGFKEIIK_01316 4.47e-13 - - - - - - - -
FGFKEIIK_01317 6.15e-95 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
FGFKEIIK_01318 1.5e-171 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_01319 7.69e-232 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
FGFKEIIK_01320 8.46e-197 ytmP - - M - - - Phosphotransferase
FGFKEIIK_01321 4.36e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
FGFKEIIK_01323 3.35e-289 ytfP - - S ko:K07007 - ko00000 Flavoprotein
FGFKEIIK_01324 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
FGFKEIIK_01325 1.23e-82 XK27_02560 - - S - - - cog cog2151
FGFKEIIK_01326 8.12e-80 WQ51_02910 - - S - - - Protein of unknown function, DUF536
FGFKEIIK_01327 2.17e-134 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
FGFKEIIK_01328 6.01e-167 - - - K - - - transcriptional regulator, MerR family
FGFKEIIK_01329 6.16e-38 - - - L - - - transposase activity
FGFKEIIK_01330 5.31e-59 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FGFKEIIK_01332 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
FGFKEIIK_01333 7.11e-68 - - - - - - - -
FGFKEIIK_01334 2.72e-56 MA20_20425 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 - E ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
FGFKEIIK_01335 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGFKEIIK_01336 1.01e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
FGFKEIIK_01337 2.69e-231 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGFKEIIK_01338 2.28e-172 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
FGFKEIIK_01339 1.53e-128 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
FGFKEIIK_01340 1.37e-288 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FGFKEIIK_01341 6.12e-184 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
FGFKEIIK_01342 4.28e-97 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor, CopY TcrY family
FGFKEIIK_01343 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
FGFKEIIK_01344 9.48e-43 copZ - - P - - - Heavy metal-associated domain protein
FGFKEIIK_01345 9.64e-248 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
FGFKEIIK_01346 1.22e-148 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_01347 1.32e-147 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_01348 2.01e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
FGFKEIIK_01349 9.46e-200 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
FGFKEIIK_01353 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
FGFKEIIK_01354 1.63e-155 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
FGFKEIIK_01355 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FGFKEIIK_01356 1.09e-257 yjbB - - G - - - Permeases of the major facilitator superfamily
FGFKEIIK_01357 5.28e-203 rgg - - K - - - Transcriptional activator, Rgg GadR MutR family
FGFKEIIK_01358 4.57e-129 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
FGFKEIIK_01359 7.5e-83 yjqA - - S - - - Bacterial PH domain
FGFKEIIK_01360 5.05e-204 corA - - P - - - CorA-like protein
FGFKEIIK_01361 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
FGFKEIIK_01362 4.12e-56 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
FGFKEIIK_01363 1.5e-181 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
FGFKEIIK_01364 8.44e-186 nodB3 - - G - - - deacetylase
FGFKEIIK_01365 2.5e-183 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
FGFKEIIK_01366 2.9e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
FGFKEIIK_01367 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
FGFKEIIK_01368 2.13e-295 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGFKEIIK_01369 2.39e-126 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
FGFKEIIK_01370 1.06e-295 ytoI - - K - - - transcriptional regulator containing CBS domains
FGFKEIIK_01371 4.94e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
FGFKEIIK_01372 1.03e-205 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
FGFKEIIK_01373 3.26e-110 ccl - - S - - - cog cog4708
FGFKEIIK_01374 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGFKEIIK_01375 7.79e-237 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
FGFKEIIK_01376 1.43e-115 - - - L - - - Transposase DDE domain
FGFKEIIK_01377 1.22e-97 - - - S - - - QueT transporter
FGFKEIIK_01378 2.43e-202 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
FGFKEIIK_01379 2.67e-219 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
FGFKEIIK_01380 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
FGFKEIIK_01381 9.09e-50 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
FGFKEIIK_01382 1.93e-304 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
FGFKEIIK_01383 0.0 ydaO - - E - - - amino acid
FGFKEIIK_01384 1.17e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
FGFKEIIK_01385 1.29e-188 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FGFKEIIK_01386 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
FGFKEIIK_01387 1.49e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FGFKEIIK_01388 7.94e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGFKEIIK_01389 4.06e-219 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
FGFKEIIK_01390 5.6e-272 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
FGFKEIIK_01391 2e-179 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
FGFKEIIK_01392 1.79e-171 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
FGFKEIIK_01393 3.44e-263 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
FGFKEIIK_01394 4.81e-25 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
FGFKEIIK_01395 6.33e-71 XK27_08050 - - O - - - stress-induced mitochondrial fusion
FGFKEIIK_01396 1.61e-93 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
FGFKEIIK_01397 5.76e-124 - - - GK - - - ROK family
FGFKEIIK_01398 3.61e-267 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FGFKEIIK_01399 3.26e-135 - - - M - - - Acetyltransferase GNAT family
FGFKEIIK_01400 2.15e-280 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGFKEIIK_01401 3.47e-72 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
FGFKEIIK_01402 3.55e-79 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
FGFKEIIK_01404 4.04e-77 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
FGFKEIIK_01405 3.76e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 effector of murein hydrolase
FGFKEIIK_01406 1.07e-141 - - - S - - - IA, variant 1
FGFKEIIK_01407 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGFKEIIK_01408 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FGFKEIIK_01409 7.46e-149 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
FGFKEIIK_01410 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FGFKEIIK_01411 2.97e-210 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FGFKEIIK_01412 7.78e-69 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FGFKEIIK_01413 1.22e-140 csn2 - - S ko:K19137 - ko00000,ko02048 CRISPR-associated protein (Cas_Csn2)
FGFKEIIK_01415 1.61e-197 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
FGFKEIIK_01417 1.17e-40 ycaO - - O ko:K06889,ko:K07397,ko:K09136 - ko00000,ko03009 OsmC-like protein
FGFKEIIK_01418 1.25e-85 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
FGFKEIIK_01421 2.22e-173 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
FGFKEIIK_01422 8.41e-11 - - - S - - - Protein of unknown function (DUF4044)
FGFKEIIK_01423 1.9e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGFKEIIK_01424 1.84e-24 XK27_00735 - - - - - - -
FGFKEIIK_01425 8.35e-175 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
FGFKEIIK_01426 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
FGFKEIIK_01427 6.37e-40 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
FGFKEIIK_01428 3.3e-72 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
FGFKEIIK_01430 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FGFKEIIK_01431 2.15e-109 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
FGFKEIIK_01432 6.76e-185 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
FGFKEIIK_01433 7.6e-176 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
FGFKEIIK_01434 9.57e-268 arcT - - E - - - Aminotransferase
FGFKEIIK_01435 4.07e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
FGFKEIIK_01436 1.9e-27 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
FGFKEIIK_01437 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
FGFKEIIK_01438 3.03e-257 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FGFKEIIK_01439 1.98e-73 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
FGFKEIIK_01440 7.3e-216 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
FGFKEIIK_01441 3.02e-312 - - - - - - - -
FGFKEIIK_01442 1.9e-207 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
FGFKEIIK_01443 1.97e-160 - - - S - - - Glycosyl transferase family 2
FGFKEIIK_01444 3.81e-64 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
FGFKEIIK_01445 5.33e-272 rgpX3 - - S - - - polysaccharide biosynthetic process
FGFKEIIK_01446 1.33e-160 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 transferase activity, transferring glycosyl groups
FGFKEIIK_01447 1.31e-170 - - - S - - - Predicted membrane protein (DUF2142)
FGFKEIIK_01448 3.29e-285 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
FGFKEIIK_01449 5.23e-230 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
FGFKEIIK_01450 4.54e-183 rgpC - - GM ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
FGFKEIIK_01451 2.09e-287 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
FGFKEIIK_01452 1.35e-236 rgpE - GT2 M ko:K12998 - ko00000,ko01000,ko01003,ko01005 COG0463 Glycosyltransferases involved in cell wall biogenesis
FGFKEIIK_01453 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
FGFKEIIK_01454 1.61e-154 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
FGFKEIIK_01455 4.49e-167 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
FGFKEIIK_01456 2.81e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FGFKEIIK_01457 1.46e-77 XK27_04120 - - S - - - Putative amino acid metabolism
FGFKEIIK_01458 4.54e-264 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
FGFKEIIK_01459 2.07e-226 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGFKEIIK_01460 5.5e-134 yjbK - - S - - - Adenylate cyclase
FGFKEIIK_01461 1.24e-156 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
FGFKEIIK_01462 1.56e-193 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGFKEIIK_01463 1.81e-220 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
FGFKEIIK_01464 1.15e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
FGFKEIIK_01465 4.61e-101 - - - L - - - Transposase
FGFKEIIK_01466 4.08e-123 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_01467 1.24e-279 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
FGFKEIIK_01468 2.09e-51 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
FGFKEIIK_01469 7.95e-59 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FGFKEIIK_01470 1.72e-30 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FGFKEIIK_01471 2.84e-203 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
FGFKEIIK_01472 7.37e-60 - - - L ko:K07483 - ko00000 Transposase
FGFKEIIK_01473 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
FGFKEIIK_01474 4.4e-290 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_01475 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
FGFKEIIK_01476 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_01477 2.01e-213 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_01478 8.41e-260 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FGFKEIIK_01479 3.46e-218 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FGFKEIIK_01480 2.73e-172 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
FGFKEIIK_01481 2.9e-159 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_01482 2.43e-83 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
FGFKEIIK_01483 1.63e-190 - - - S - - - overlaps another CDS with the same product name
FGFKEIIK_01484 7.18e-193 XK27_02985 - - S - - - overlaps another CDS with the same product name
FGFKEIIK_01485 8.97e-309 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FGFKEIIK_01486 3.57e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
FGFKEIIK_01487 6.79e-62 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
FGFKEIIK_01488 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FGFKEIIK_01489 4.26e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGFKEIIK_01490 1.1e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGFKEIIK_01491 7.75e-170 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
FGFKEIIK_01492 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
FGFKEIIK_01493 4.61e-156 yvqF - - KT ko:K11622 ko02020,map02020 ko00000,ko00001 membrane
FGFKEIIK_01494 1.12e-224 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FGFKEIIK_01495 8.07e-148 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FGFKEIIK_01498 6.44e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGFKEIIK_01499 1.15e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
FGFKEIIK_01500 8.16e-241 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
FGFKEIIK_01501 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
FGFKEIIK_01502 1.17e-147 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
FGFKEIIK_01503 1.58e-39 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
FGFKEIIK_01504 2.67e-186 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
FGFKEIIK_01505 1.03e-80 - - - L - - - Transposase
FGFKEIIK_01506 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
FGFKEIIK_01507 1.91e-47 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
FGFKEIIK_01508 4.19e-124 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
FGFKEIIK_01509 8.99e-24 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
FGFKEIIK_01510 1.38e-276 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
FGFKEIIK_01511 1.18e-34 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_01512 6.92e-13 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_01513 1.4e-236 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
FGFKEIIK_01514 1.57e-280 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FGFKEIIK_01515 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
FGFKEIIK_01516 6.03e-248 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
FGFKEIIK_01517 1.19e-257 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
FGFKEIIK_01518 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 transporter
FGFKEIIK_01519 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
FGFKEIIK_01520 2.27e-293 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
FGFKEIIK_01521 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
FGFKEIIK_01522 1.48e-119 - - - - - - - -
FGFKEIIK_01524 7.51e-71 - - - L ko:K07483 - ko00000 transposase activity
FGFKEIIK_01525 2.1e-24 - - - L ko:K07483 - ko00000 transposase activity
FGFKEIIK_01526 6.28e-193 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_01527 7.24e-205 - - - K - - - Transcriptional activator, Rgg GadR MutR family
FGFKEIIK_01529 3.57e-24 - - - I - - - radical SAM domain protein
FGFKEIIK_01530 3.19e-290 - - - I - - - radical SAM domain protein
FGFKEIIK_01531 6.25e-227 - - - EGP - - - Major Facilitator Superfamily
FGFKEIIK_01532 5.73e-137 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
FGFKEIIK_01533 2.93e-10 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
FGFKEIIK_01534 1.31e-195 - - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MatE
FGFKEIIK_01535 1.62e-152 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_01536 1.47e-226 hrtB - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
FGFKEIIK_01538 0.0 - - - M - - - family 8
FGFKEIIK_01539 1.96e-12 - - - - - - - -
FGFKEIIK_01540 6.23e-11 - - - - - - - -
FGFKEIIK_01541 4.88e-140 - - - E - - - LysE type translocator
FGFKEIIK_01543 1.08e-14 - - - IQ - - - PFAM AMP-dependent synthetase and ligase
FGFKEIIK_01544 5.47e-44 - - - - - - - -
FGFKEIIK_01545 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGFKEIIK_01546 1.49e-81 - - - - - - - -
FGFKEIIK_01547 1.07e-86 - - - S - - - Signal peptide protein, YSIRK family
FGFKEIIK_01548 4.43e-71 saeR - - K ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
FGFKEIIK_01550 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
FGFKEIIK_01551 2.74e-231 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
FGFKEIIK_01552 2.63e-204 yvgN - - C - - - reductase
FGFKEIIK_01553 1.33e-136 - - - S - - - Protein of unknown function (DUF1275)
FGFKEIIK_01554 2.35e-142 ydgI - - C - - - Nitroreductase
FGFKEIIK_01555 1.19e-294 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FGFKEIIK_01556 1.07e-202 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
FGFKEIIK_01557 2.96e-100 ywnA_2 - - K - - - Transcriptional regulator
FGFKEIIK_01558 1.37e-192 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
FGFKEIIK_01559 3.47e-142 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
FGFKEIIK_01560 4.6e-294 yfnA - - E ko:K03294 - ko00000 amino acid
FGFKEIIK_01561 5.5e-34 csbD - - K - - - CsbD-like
FGFKEIIK_01562 3.23e-75 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
FGFKEIIK_01563 2.22e-85 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
FGFKEIIK_01564 4.2e-301 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
FGFKEIIK_01565 8.17e-241 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGFKEIIK_01566 2.78e-316 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
FGFKEIIK_01567 1.48e-153 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
FGFKEIIK_01568 4.96e-86 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
FGFKEIIK_01569 1e-99 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
FGFKEIIK_01570 2.13e-158 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FGFKEIIK_01571 9.46e-213 - - - T - - - Histidine kinase
FGFKEIIK_01572 8.96e-173 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
FGFKEIIK_01573 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
FGFKEIIK_01574 1.61e-120 - - - S ko:K06940 - ko00000 Fe-S-cluster oxidoreductase
FGFKEIIK_01577 7.76e-33 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 'abc transporter, ATP-binding protein
FGFKEIIK_01578 1.77e-158 - - - S - - - An automated process has identified a potential problem with this gene model
FGFKEIIK_01580 3.53e-54 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
FGFKEIIK_01581 1.05e-195 mutR - - K - - - Transcriptional activator, Rgg GadR MutR family
FGFKEIIK_01582 0.0 - 2.7.7.73, 2.7.7.80 - E ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 metalloendopeptidase activity
FGFKEIIK_01583 3.36e-272 - - - EGP - - - Major facilitator Superfamily
FGFKEIIK_01587 2.94e-203 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_01588 2.48e-171 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
FGFKEIIK_01589 5.97e-246 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FGFKEIIK_01590 4.01e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FGFKEIIK_01591 2.45e-128 - - - S ko:K01992 - ko00000,ko00002,ko02000 transport system, permease component
FGFKEIIK_01592 3.56e-189 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
FGFKEIIK_01594 2.3e-130 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
FGFKEIIK_01595 1.88e-39 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
FGFKEIIK_01596 4.85e-158 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
FGFKEIIK_01597 7.76e-168 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
FGFKEIIK_01598 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FGFKEIIK_01599 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGFKEIIK_01600 8.38e-42 - - - - - - - -
FGFKEIIK_01601 1.94e-16 - - - - - - - -
FGFKEIIK_01602 5.31e-120 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
FGFKEIIK_01603 2.9e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGFKEIIK_01604 6.31e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGFKEIIK_01605 1.69e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FGFKEIIK_01606 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
FGFKEIIK_01607 1.96e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGFKEIIK_01608 1.07e-120 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FGFKEIIK_01609 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FGFKEIIK_01612 2.66e-74 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
FGFKEIIK_01613 1.03e-304 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FGFKEIIK_01615 1.46e-112 - - - S - - - ECF-type riboflavin transporter, S component
FGFKEIIK_01616 4.85e-56 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
FGFKEIIK_01617 4.44e-108 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
FGFKEIIK_01618 3.43e-107 - - - S - - - ECF-type riboflavin transporter, S component
FGFKEIIK_01619 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
FGFKEIIK_01620 0.0 noxE - - P - - - NADH oxidase
FGFKEIIK_01621 2.06e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
FGFKEIIK_01622 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGFKEIIK_01623 6e-167 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
FGFKEIIK_01624 1.88e-67 ywkD - - E ko:K08234 - ko00000 COG0346 LactoylglutaTHIone lyase and related lyases
FGFKEIIK_01625 3.42e-212 ypuA - - S - - - secreted protein
FGFKEIIK_01626 1.28e-35 - - - L - - - Transposase (IS116 IS110 IS902 family)
FGFKEIIK_01627 3.37e-92 - - - L - - - Transposase (IS116 IS110 IS902 family)
FGFKEIIK_01629 8.44e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGFKEIIK_01630 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGFKEIIK_01631 3.36e-46 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
FGFKEIIK_01632 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FGFKEIIK_01633 8.58e-271 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
FGFKEIIK_01634 8.43e-282 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
FGFKEIIK_01635 3.31e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
FGFKEIIK_01636 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGFKEIIK_01637 0.0 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_01638 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
FGFKEIIK_01639 5.79e-39 - 6.3.2.2, 6.3.2.4 - F ko:K01919,ko:K01921 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502 ko00000,ko00001,ko00002,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
FGFKEIIK_01640 9.56e-245 yfmL - - L - - - DEAD DEAH box helicase
FGFKEIIK_01641 2.24e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
FGFKEIIK_01642 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
FGFKEIIK_01643 4.3e-169 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
FGFKEIIK_01644 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGFKEIIK_01645 1.02e-192 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
FGFKEIIK_01646 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
FGFKEIIK_01647 1.15e-160 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FGFKEIIK_01648 1.47e-217 ybbR - - S - - - Protein conserved in bacteria
FGFKEIIK_01649 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGFKEIIK_01650 2.86e-92 mesH - - S - - - GtrA-like protein
FGFKEIIK_01651 9.04e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
FGFKEIIK_01652 1.15e-189 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FGFKEIIK_01653 4.63e-18 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
FGFKEIIK_01654 3.79e-39 zupT - - P ko:K07238 - ko00000,ko02000 transporter
FGFKEIIK_01655 6.9e-261 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
FGFKEIIK_01656 7.83e-206 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FGFKEIIK_01657 4.07e-144 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
FGFKEIIK_01658 3.31e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
FGFKEIIK_01659 1.8e-308 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_01662 3.27e-277 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
FGFKEIIK_01663 7.79e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
FGFKEIIK_01664 6.89e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
FGFKEIIK_01665 1.2e-158 - - - S - - - tigr01906
FGFKEIIK_01666 2.41e-181 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
FGFKEIIK_01667 2.04e-17 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
FGFKEIIK_01668 1.5e-119 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
FGFKEIIK_01669 1.5e-30 XK27_08085 - - - - - - -
FGFKEIIK_01670 8.74e-49 - - - L ko:K07483 - ko00000 transposase activity
FGFKEIIK_01671 2.82e-29 - - - L - - - Transposase
FGFKEIIK_01672 2.66e-74 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_01673 1.74e-42 - - - L ko:K07497 - ko00000 Integrase core domain protein
FGFKEIIK_01675 3.66e-253 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGFKEIIK_01676 9.09e-235 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FGFKEIIK_01677 8.39e-151 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
FGFKEIIK_01678 2.16e-300 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FGFKEIIK_01679 4.07e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
FGFKEIIK_01680 2.08e-144 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FGFKEIIK_01681 1.75e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FGFKEIIK_01682 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FGFKEIIK_01683 7.31e-81 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FGFKEIIK_01684 7.62e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP
FGFKEIIK_01685 0.0 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
FGFKEIIK_01686 1.01e-251 - - - L ko:K07481 - ko00000 transposase, IS4 family
FGFKEIIK_01687 1.42e-286 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FGFKEIIK_01688 1.15e-152 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
FGFKEIIK_01689 4.43e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
FGFKEIIK_01690 4.46e-179 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
FGFKEIIK_01691 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
FGFKEIIK_01692 6.44e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGFKEIIK_01693 5.91e-234 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FGFKEIIK_01694 9.02e-163 dnaD - - - ko:K02086 - ko00000 -
FGFKEIIK_01695 3.81e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FGFKEIIK_01697 9.08e-314 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FGFKEIIK_01698 1.72e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease VII activity
FGFKEIIK_01699 1.35e-202 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
FGFKEIIK_01700 2.83e-203 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
FGFKEIIK_01701 1.72e-94 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
FGFKEIIK_01702 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
FGFKEIIK_01703 1.18e-190 WQ51_01275 - - S - - - DegV family
FGFKEIIK_01704 4.24e-185 ypmR - - E - - - lipolytic protein G-D-S-L family
FGFKEIIK_01705 2.09e-124 ypmS - - S - - - Protein conserved in bacteria
FGFKEIIK_01706 1.54e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FGFKEIIK_01708 2.31e-230 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
FGFKEIIK_01709 3.05e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FGFKEIIK_01710 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGFKEIIK_01711 7.51e-242 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
FGFKEIIK_01712 1.64e-57 ysdA - - L - - - Membrane
FGFKEIIK_01713 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGFKEIIK_01714 2.76e-146 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGFKEIIK_01715 8.12e-194 XK27_00020 - - J - - - Belongs to the SUA5 family
FGFKEIIK_01716 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
FGFKEIIK_01717 1.04e-239 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
FGFKEIIK_01718 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
FGFKEIIK_01719 0.0 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_01721 6.86e-11 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
FGFKEIIK_01722 1.68e-31 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
FGFKEIIK_01723 9.67e-49 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
FGFKEIIK_01726 2.91e-230 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
FGFKEIIK_01727 6.79e-191 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
FGFKEIIK_01728 2.68e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
FGFKEIIK_01729 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FGFKEIIK_01730 7.51e-194 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
FGFKEIIK_01731 3.12e-162 XK27_08875 - - O - - - Zinc-dependent metalloprotease
FGFKEIIK_01733 1.42e-97 ykuP - - C ko:K03839 - ko00000 Flavodoxin
FGFKEIIK_01734 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
FGFKEIIK_01735 1.27e-55 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
FGFKEIIK_01736 4.32e-279 - - - P - - - chloride
FGFKEIIK_01737 5.73e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FGFKEIIK_01740 2.71e-27 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
FGFKEIIK_01741 1.05e-209 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGFKEIIK_01742 1.12e-116 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
FGFKEIIK_01743 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FGFKEIIK_01744 2.38e-223 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FGFKEIIK_01745 5.75e-267 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGFKEIIK_01746 1.92e-19 - - - G - - - Domain of unknown function (DUF4832)
FGFKEIIK_01747 5.18e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
FGFKEIIK_01749 1.45e-296 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGFKEIIK_01750 4.09e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
FGFKEIIK_01751 6.78e-177 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
FGFKEIIK_01752 3.52e-143 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
FGFKEIIK_01753 8.31e-159 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_01754 9.79e-194 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
FGFKEIIK_01755 5.43e-180 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
FGFKEIIK_01756 2.49e-166 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FGFKEIIK_01757 9.32e-316 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FGFKEIIK_01758 1.46e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
FGFKEIIK_01759 2.51e-47 - - - F ko:K09790 - ko00000 Protein of unknown function (DUF454)
FGFKEIIK_01760 2.58e-294 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
FGFKEIIK_01761 5.66e-189 XK27_00835 - - S - - - hydrolases of the HAD superfamily
FGFKEIIK_01762 1.69e-60 XK27_00115 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
FGFKEIIK_01763 1.19e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
FGFKEIIK_01764 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
FGFKEIIK_01765 1.38e-174 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
FGFKEIIK_01766 2.9e-229 - - - S - - - Calcineurin-like phosphoesterase
FGFKEIIK_01767 1.52e-263 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FGFKEIIK_01768 5.35e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FGFKEIIK_01769 7.31e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
FGFKEIIK_01770 1.99e-209 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
FGFKEIIK_01771 2.48e-120 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
FGFKEIIK_01772 1.22e-231 XK27_05220 - - S - - - permease
FGFKEIIK_01773 1.34e-285 XK27_05225 - - G - - - COG0457 FOG TPR repeat
FGFKEIIK_01774 1.95e-127 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
FGFKEIIK_01775 4.32e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
FGFKEIIK_01776 1.12e-119 ebsA - - S - - - Family of unknown function (DUF5322)
FGFKEIIK_01777 3.03e-105 XK27_09115 - - M - - - LysM domain
FGFKEIIK_01778 1.44e-156 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
FGFKEIIK_01779 3.15e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FGFKEIIK_01780 5.79e-39 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
FGFKEIIK_01781 1.82e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FGFKEIIK_01782 1.15e-32 - - - L ko:K07491 - ko00000 Transposase
FGFKEIIK_01783 1.39e-111 XK27_03610 - - K - - - Gnat family
FGFKEIIK_01784 2.78e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
FGFKEIIK_01785 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
FGFKEIIK_01786 1.95e-145 ung2 - - L - - - Uracil-DNA glycosylase
FGFKEIIK_01789 7.14e-157 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FGFKEIIK_01790 3.95e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
FGFKEIIK_01791 5.38e-54 - - - S - - - Protein of unknown function (DUF1697)
FGFKEIIK_01792 3.56e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FGFKEIIK_01793 3.11e-80 clcA2 - - P - - - chloride
FGFKEIIK_01794 1.12e-86 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
FGFKEIIK_01795 2.67e-48 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
FGFKEIIK_01796 9.39e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
FGFKEIIK_01797 7.54e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_01798 0.0 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
FGFKEIIK_01799 3.83e-174 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
FGFKEIIK_01800 4.17e-142 capA - - M - - - biosynthesis protein
FGFKEIIK_01801 3.4e-143 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
FGFKEIIK_01802 2.55e-07 cpsE - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
FGFKEIIK_01803 0.0 cpsE - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
FGFKEIIK_01804 6.38e-29 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 group 1 family protein
FGFKEIIK_01805 7.14e-93 - - - L - - - Transposase DDE domain
FGFKEIIK_01806 4.35e-78 - - - L - - - Transposase DDE domain
FGFKEIIK_01807 9e-90 - - - M - - - Domain of unknown function (DUF4422)
FGFKEIIK_01808 1.04e-126 - - - - - - - -
FGFKEIIK_01809 1.98e-127 - - - M - - - group 2 family protein
FGFKEIIK_01810 3.62e-42 ywqD - - D - - - Capsular exopolysaccharide family
FGFKEIIK_01811 3.29e-110 - - - M - - - Glycosyltransferase like family 2
FGFKEIIK_01812 7.24e-303 cps1C - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
FGFKEIIK_01813 7.87e-216 wzx - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
FGFKEIIK_01814 2.63e-25 wzx - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
FGFKEIIK_01815 9.66e-275 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
FGFKEIIK_01816 2.45e-230 - - - L - - - Transposase
FGFKEIIK_01817 6.98e-124 - - - V - - - VanZ like family
FGFKEIIK_01818 6.28e-19 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
FGFKEIIK_01819 8.95e-91 supH 3.1.3.102, 3.1.3.104 - Q ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 phosphatase activity
FGFKEIIK_01820 2.23e-115 - - - G - - - Belongs to the phosphoglycerate mutase family
FGFKEIIK_01821 1.68e-254 XK27_12525 - - S - - - hmm pf01594
FGFKEIIK_01822 1.74e-22 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
FGFKEIIK_01823 1.96e-172 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
FGFKEIIK_01824 3.34e-52 - - - S - - - granule-associated protein
FGFKEIIK_01825 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
FGFKEIIK_01826 3.14e-38 - - - E - - - Lysophospholipase L1 and related esterases
FGFKEIIK_01827 3.75e-90 - - - E - - - GDSL-like protein
FGFKEIIK_01828 4.34e-200 - - - S - - - Phospholipase, patatin family
FGFKEIIK_01829 7.17e-106 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
FGFKEIIK_01830 4.7e-33 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
FGFKEIIK_01831 1.12e-31 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
FGFKEIIK_01832 5.27e-32 dacA1 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
FGFKEIIK_01833 5.21e-275 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FGFKEIIK_01834 6.69e-162 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGFKEIIK_01835 3.43e-299 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
FGFKEIIK_01836 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
FGFKEIIK_01837 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 CRISPR-associated helicase cas3
FGFKEIIK_01838 0.0 casA - - L ko:K19123 - ko00000,ko02048 the current gene model (or a revised gene model) may contain a frame shift
FGFKEIIK_01839 1.65e-134 casB - - S ko:K19046 - ko00000,ko02048 CRISPR system CASCADE complex protein CasB
FGFKEIIK_01840 2.89e-232 casC - - L ko:K19124 - ko00000,ko02048 CT1975-like protein
FGFKEIIK_01841 2.03e-171 casD - - S ko:K19125 - ko00000,ko02048 CRISPR system CASCADE complex protein CasD
FGFKEIIK_01842 6.11e-142 casE - - S ko:K19126 - ko00000,ko02048 CRISPR system CASCADE complex protein CasE
FGFKEIIK_01843 2.64e-216 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FGFKEIIK_01844 1.7e-206 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR-associated endoribonuclease Cas2
FGFKEIIK_01845 1.19e-65 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
FGFKEIIK_01846 5.9e-46 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
FGFKEIIK_01847 8.81e-105 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
FGFKEIIK_01848 2.53e-55 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
FGFKEIIK_01849 1.07e-236 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
FGFKEIIK_01850 3.38e-232 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FGFKEIIK_01851 1.05e-275 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FGFKEIIK_01852 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
FGFKEIIK_01853 3.13e-14 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
FGFKEIIK_01854 3.83e-79 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
FGFKEIIK_01855 1.84e-143 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
FGFKEIIK_01856 2.03e-158 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
FGFKEIIK_01857 1.89e-83 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
FGFKEIIK_01858 5.89e-70 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
FGFKEIIK_01859 4.24e-111 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
FGFKEIIK_01860 2.83e-41 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
FGFKEIIK_01861 1.91e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGFKEIIK_01862 1.02e-213 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGFKEIIK_01863 1.75e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
FGFKEIIK_01864 6.83e-232 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
FGFKEIIK_01865 3.04e-200 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
FGFKEIIK_01866 7.41e-297 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
FGFKEIIK_01867 0.0 ywbL - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
FGFKEIIK_01868 1.83e-156 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGFKEIIK_01869 4.79e-34 tatA - - U ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein secretion
FGFKEIIK_01871 5.89e-61 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
FGFKEIIK_01872 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
FGFKEIIK_01873 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
FGFKEIIK_01876 7.23e-238 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
FGFKEIIK_01877 1.88e-249 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
FGFKEIIK_01878 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
FGFKEIIK_01879 7.71e-148 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
FGFKEIIK_01880 1.75e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FGFKEIIK_01881 5.27e-193 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FGFKEIIK_01882 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
FGFKEIIK_01883 4.63e-201 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
FGFKEIIK_01884 2.07e-202 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
FGFKEIIK_01885 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
FGFKEIIK_01886 8.38e-184 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
FGFKEIIK_01887 1.99e-58 yktA - - S - - - Belongs to the UPF0223 family
FGFKEIIK_01888 7.52e-95 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
FGFKEIIK_01889 1.28e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
FGFKEIIK_01890 5.24e-195 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGFKEIIK_01891 5.47e-61 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
FGFKEIIK_01892 1.02e-124 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
FGFKEIIK_01893 3.31e-143 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
FGFKEIIK_01894 2.99e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FGFKEIIK_01895 5.48e-79 - - - S - - - haloacid dehalogenase-like hydrolase
FGFKEIIK_01896 6.24e-78 - - - Q - - - phosphatase activity
FGFKEIIK_01897 2.95e-307 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
FGFKEIIK_01898 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
FGFKEIIK_01899 7.07e-307 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
FGFKEIIK_01900 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FGFKEIIK_01901 4.64e-135 yfiF3 - - K - - - sequence-specific DNA binding
FGFKEIIK_01902 1.56e-45 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 nucleotide catabolic process
FGFKEIIK_01903 0.0 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
FGFKEIIK_01904 1.17e-05 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
FGFKEIIK_01905 1.02e-28 yecS - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 amino acid transport
FGFKEIIK_01906 8.93e-82 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_01907 0.0 dtpT - - E ko:K03305 - ko00000 transporter
FGFKEIIK_01908 6.37e-09 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 amidase activity
FGFKEIIK_01909 4.34e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGFKEIIK_01910 2.2e-158 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
FGFKEIIK_01911 1.46e-30 - - - S - - - Psort location Cytoplasmic, score
FGFKEIIK_01912 5.24e-10 - - - S - - - Psort location Cytoplasmic, score
FGFKEIIK_01913 2.24e-262 csm5 - - L ko:K19140 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm5 family
FGFKEIIK_01914 1.04e-215 csm4 - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
FGFKEIIK_01915 9.77e-152 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
FGFKEIIK_01916 1.29e-83 csm2 - - L ko:K19138 - ko00000,ko02048 Csm2 Type III-A
FGFKEIIK_01917 0.0 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
FGFKEIIK_01918 7.74e-174 cas6 - - S ko:K19091 - ko00000,ko01000,ko02048 CRISPR-associated endoribonuclease Cas6
FGFKEIIK_01919 7.15e-73 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FGFKEIIK_01920 5.07e-236 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FGFKEIIK_01921 7.37e-224 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FGFKEIIK_01922 8.38e-190 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
FGFKEIIK_01923 1.23e-124 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
FGFKEIIK_01924 3.54e-114 - - - S - - - TraX protein
FGFKEIIK_01925 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
FGFKEIIK_01927 1.89e-23 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
FGFKEIIK_01928 3.18e-31 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
FGFKEIIK_01929 6.95e-152 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
FGFKEIIK_01930 9.83e-187 - - - F - - - Phosphorylase superfamily
FGFKEIIK_01933 2.43e-103 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
FGFKEIIK_01934 3.95e-24 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
FGFKEIIK_01935 2.92e-11 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
FGFKEIIK_01936 2.78e-250 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
FGFKEIIK_01937 8.27e-269 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
FGFKEIIK_01938 3.17e-205 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
FGFKEIIK_01939 1.89e-127 - - - K - - - Transcriptional regulator, TetR family
FGFKEIIK_01940 9.28e-15 - - - - - - - -
FGFKEIIK_01941 3.51e-146 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
FGFKEIIK_01942 1.52e-125 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_01943 2e-207 - - - L ko:K07485 - ko00000 Transposase
FGFKEIIK_01945 5.45e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
FGFKEIIK_01946 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
FGFKEIIK_01947 9.01e-75 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
FGFKEIIK_01948 3.67e-174 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
FGFKEIIK_01949 3.68e-271 nirJ - - C ko:K06139,ko:K22227 - ko00000 radical SAM domain protein
FGFKEIIK_01951 7.54e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_01953 1.77e-200 - - - K - - - Transcriptional activator, Rgg GadR MutR family
FGFKEIIK_01954 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FGFKEIIK_01956 1.66e-57 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
FGFKEIIK_01957 2.52e-50 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
FGFKEIIK_01958 6.02e-64 pspE - - P ko:K03972 - ko00000 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGFKEIIK_01959 1.01e-99 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
FGFKEIIK_01960 1.4e-195 XK27_05470 - - E - - - Methionine synthase
FGFKEIIK_01961 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FGFKEIIK_01962 0.0 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
FGFKEIIK_01963 2.93e-157 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FGFKEIIK_01964 2.32e-195 - - - S - - - TraX protein
FGFKEIIK_01965 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGFKEIIK_01966 9.91e-204 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
FGFKEIIK_01967 4.4e-216 - - - GK - - - ROK family
FGFKEIIK_01968 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGFKEIIK_01969 1.46e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FGFKEIIK_01970 5.25e-165 - - - K - - - DNA-binding helix-turn-helix protein
FGFKEIIK_01971 1.3e-116 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
FGFKEIIK_01972 8e-113 niaX - - - ko:K16788 - ko00000,ko02000 -
FGFKEIIK_01973 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGFKEIIK_01974 9e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FGFKEIIK_01975 1.82e-162 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
FGFKEIIK_01976 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
FGFKEIIK_01977 4.62e-94 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
FGFKEIIK_01978 7.7e-39 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
FGFKEIIK_01979 1.65e-22 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
FGFKEIIK_01980 3.67e-78 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
FGFKEIIK_01981 2.8e-36 - - - - - - - -
FGFKEIIK_01982 2.18e-10 - - - - - - - -
FGFKEIIK_01983 4.5e-177 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGFKEIIK_01984 5.5e-203 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
FGFKEIIK_01985 5.28e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
FGFKEIIK_01986 3.92e-134 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
FGFKEIIK_01987 7.71e-77 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
FGFKEIIK_01988 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
FGFKEIIK_01989 8.86e-214 cpsY - - K - - - Transcriptional regulator
FGFKEIIK_01990 9.47e-107 - - - L ko:K07497 - ko00000 transposition
FGFKEIIK_01991 1.86e-153 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
FGFKEIIK_01992 4.73e-221 yeiH - - S - - - Membrane
FGFKEIIK_01995 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
FGFKEIIK_01996 1.69e-128 XK27_10720 - - D - - - peptidase activity
FGFKEIIK_01997 9.11e-112 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
FGFKEIIK_01998 1.33e-07 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
FGFKEIIK_01999 9.82e-203 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
FGFKEIIK_02000 1.1e-143 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
FGFKEIIK_02001 3.85e-72 hsdS 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K07317 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
FGFKEIIK_02002 1.21e-112 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_02003 9.08e-51 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_02004 7.07e-40 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_02005 6.38e-77 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
FGFKEIIK_02006 8.39e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
FGFKEIIK_02007 1.8e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
FGFKEIIK_02008 2.63e-243 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
FGFKEIIK_02009 2.21e-282 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_02010 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 P-type ATPase
FGFKEIIK_02011 9.84e-225 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_02012 1.29e-40 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FGFKEIIK_02013 4.58e-156 - - - L - - - Transposase
FGFKEIIK_02014 1.53e-212 - - - L ko:K07497 - ko00000 integrase core domain
FGFKEIIK_02015 8.77e-56 cspA - - K ko:K03704 - ko00000,ko03000 Cold-Shock Protein
FGFKEIIK_02016 2.63e-44 - - - K - - - Cold shock protein domain
FGFKEIIK_02017 1.19e-51 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 dipeptidase activity
FGFKEIIK_02018 1.16e-121 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
FGFKEIIK_02019 5.15e-190 whiA - - K ko:K09762 - ko00000 May be required for sporulation
FGFKEIIK_02020 2.06e-48 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
FGFKEIIK_02021 1.98e-39 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)