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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HCIEDONB_00001	1.4e-46	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HCIEDONB_00002	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HCIEDONB_00003	7.49e-209	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HCIEDONB_00004	6.59e-106	-	-	-	S	-	-	-	Heat induced stress protein YflT
HCIEDONB_00005	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HCIEDONB_00007	1.4e-154	-	-	-	S	-	-	-	Thiamine-binding protein
HCIEDONB_00008	8.33e-183	-	-	-	P	ko:K15599	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
HCIEDONB_00009	5.91e-243	M1-596	-	-	P	ko:K02051,ko:K15598	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HCIEDONB_00010	3.42e-180	-	-	-	P	ko:K02049,ko:K15600	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HCIEDONB_00011	4.92e-213	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCIEDONB_00012	2.66e-248	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HCIEDONB_00013	4.26e-309	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HCIEDONB_00014	1.38e-184	-	-	-	E	-	-	-	Belongs to the arginase family
HCIEDONB_00015	1e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HCIEDONB_00016	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCIEDONB_00017	3.21e-212	-	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HCIEDONB_00018	7.03e-62	-	-	-	S	-	-	-	Sodium pantothenate symporter
HCIEDONB_00019	1.53e-306	panF	-	-	H	ko:K14392	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCIEDONB_00022	4.08e-220	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mg2 transporter protein CorA family protein
HCIEDONB_00023	0.0	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HCIEDONB_00025	1.66e-269	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HCIEDONB_00026	2.82e-111	-	-	-	-	-	-	-	-
HCIEDONB_00027	1.08e-101	-	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HCIEDONB_00028	8.39e-180	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HCIEDONB_00030	1.86e-129	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HCIEDONB_00031	8.36e-81	-	-	-	K	-	-	-	transcriptional
HCIEDONB_00032	0.0	-	6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCIEDONB_00033	0.0	-	-	-	I	-	-	-	Acyl-CoA dehydrogenase, middle domain
HCIEDONB_00034	1.81e-224	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEDONB_00035	2.33e-200	yokD	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	aminoglycoside
HCIEDONB_00036	6.37e-296	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCIEDONB_00037	1.14e-91	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCIEDONB_00038	4.69e-39	-	-	-	-	-	-	-	-
HCIEDONB_00039	1.89e-111	-	-	-	-	-	-	-	-
HCIEDONB_00040	1.31e-290	yfkA	-	-	S	-	-	-	YfkB-like domain
HCIEDONB_00042	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HCIEDONB_00043	1.25e-62	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HCIEDONB_00044	1.24e-59	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HCIEDONB_00045	1.46e-42	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HCIEDONB_00046	2.68e-113	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HCIEDONB_00047	2.02e-108	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HCIEDONB_00049	2.8e-230	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_00050	2.79e-120	hxlB	4.1.2.43, 5.3.1.27	-	M	ko:K08093,ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	arabinose-5-phosphate isomerase activity
HCIEDONB_00051	1.84e-189	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HCIEDONB_00053	1.25e-189	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	BAAT / Acyl-CoA thioester hydrolase C terminal
HCIEDONB_00054	7.76e-188	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
HCIEDONB_00055	1.53e-58	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
HCIEDONB_00056	2.07e-147	-	-	-	M	-	-	-	Spore coat protein
HCIEDONB_00057	1.1e-176	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCIEDONB_00058	6.41e-197	morA	-	-	S	-	-	-	Aldo/keto reductase family
HCIEDONB_00059	6.45e-124	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
HCIEDONB_00060	1.37e-315	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Calcineurin-like phosphoesterase superfamily domain
HCIEDONB_00061	0.0	-	-	-	L	-	-	-	AAA domain
HCIEDONB_00062	8.37e-198	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HCIEDONB_00063	7.69e-310	-	-	-	V	-	-	-	Mate efflux family protein
HCIEDONB_00064	2.42e-87	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HCIEDONB_00065	3.32e-77	-	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HCIEDONB_00066	3.06e-144	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HCIEDONB_00067	9.51e-284	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HCIEDONB_00068	2.06e-137	-	4.1.3.17	-	H	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	ko00000,ko00001,ko01000	Methyltransferase
HCIEDONB_00069	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha-galactosidase
HCIEDONB_00070	1.4e-65	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCIEDONB_00071	0.0	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCIEDONB_00072	1.23e-182	ubiE	-	-	Q	-	-	-	Methyltransferase type 11
HCIEDONB_00073	1.53e-52	-	-	-	-	-	-	-	-
HCIEDONB_00074	9.16e-209	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
HCIEDONB_00075	2.07e-189	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HCIEDONB_00076	1.97e-113	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
HCIEDONB_00077	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HCIEDONB_00078	0.0	-	-	-	FH	ko:K03457	-	ko00000	Permease for cytosine/purines, uracil, thiamine, allantoin
HCIEDONB_00079	7.77e-103	yjhE	-	-	S	-	-	-	Phage tail protein
HCIEDONB_00081	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCIEDONB_00082	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HCIEDONB_00083	0.0	-	-	-	EGP	-	-	-	the major facilitator superfamily
HCIEDONB_00084	1.14e-142	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCIEDONB_00085	3.02e-113	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HCIEDONB_00086	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HCIEDONB_00087	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
HCIEDONB_00088	1.95e-176	lppC	-	-	M	-	-	-	5'-nucleotidase, lipoprotein e(P4)
HCIEDONB_00091	1.67e-270	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HCIEDONB_00092	1.52e-21	-	-	-	-	-	-	-	-
HCIEDONB_00093	8.45e-283	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCIEDONB_00094	6.74e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HCIEDONB_00095	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HCIEDONB_00096	1.24e-258	mro	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HCIEDONB_00097	4.51e-236	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_00098	1.15e-43	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HCIEDONB_00099	9.05e-22	-	-	-	-	-	-	-	-
HCIEDONB_00101	2.63e-207	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HCIEDONB_00102	6.3e-91	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCIEDONB_00103	1.3e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HCIEDONB_00104	7.11e-224	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HCIEDONB_00106	0.0	bmr3_1	-	-	P	ko:K18935	-	ko00000,ko02000	Major facilitator superfamily
HCIEDONB_00107	6.27e-270	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCIEDONB_00108	3.13e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCIEDONB_00109	2.38e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HCIEDONB_00110	1.97e-242	cwlS	-	CBM50	M	ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HCIEDONB_00111	1.28e-313	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HCIEDONB_00112	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HCIEDONB_00113	6.75e-226	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HCIEDONB_00114	3.57e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HCIEDONB_00115	1.96e-223	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HCIEDONB_00116	2.8e-159	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCIEDONB_00117	0.0	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HCIEDONB_00118	3.3e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_00120	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HCIEDONB_00121	1.63e-171	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HCIEDONB_00122	2.2e-91	yvyF	-	-	S	-	-	-	flagellar protein
HCIEDONB_00123	1.24e-52	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HCIEDONB_00124	1.23e-100	yvyG	-	-	NOU	-	-	-	FlgN protein
HCIEDONB_00125	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HCIEDONB_00126	1.7e-204	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HCIEDONB_00127	9.57e-106	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HCIEDONB_00128	3.42e-45	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HCIEDONB_00129	1.96e-31	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HCIEDONB_00130	1.67e-123	-	-	-	U	-	-	-	SEC-C motif
HCIEDONB_00131	7.07e-235	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HCIEDONB_00132	2.19e-125	-	-	-	K	ko:K02443	-	ko00000,ko03000	Glycerol-3-phosphate responsive antiterminator
HCIEDONB_00133	1.52e-145	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HCIEDONB_00134	1.62e-191	-	-	-	G	-	-	-	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCIEDONB_00135	6.64e-187	-	-	-	G	ko:K10709	-	ko00000	myo-inosose-2 dehydratase activity
HCIEDONB_00136	2.8e-311	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HCIEDONB_00138	1.66e-84	-	-	-	E	-	-	-	COG1113 Gamma-aminobutyrate permease and related permeases
HCIEDONB_00139	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_00140	4.05e-103	-	-	-	E	-	-	-	COG1113 Gamma-aminobutyrate permease and related permeases
HCIEDONB_00141	0.0	-	-	-	O	-	-	-	AAA domain
HCIEDONB_00143	3.6e-137	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HCIEDONB_00145	5.15e-79	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
HCIEDONB_00146	1.7e-289	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HCIEDONB_00147	1.94e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HCIEDONB_00148	8.14e-75	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HCIEDONB_00149	8.95e-127	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCIEDONB_00150	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HCIEDONB_00151	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCIEDONB_00152	5.23e-230	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCIEDONB_00153	7.2e-201	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HCIEDONB_00154	8.82e-68	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HCIEDONB_00156	6.23e-175	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HCIEDONB_00157	2.14e-201	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HCIEDONB_00158	1.19e-181	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	peptidase
HCIEDONB_00159	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCIEDONB_00160	3.66e-315	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
HCIEDONB_00161	5.45e-232	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HCIEDONB_00162	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HCIEDONB_00163	2.65e-289	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCIEDONB_00164	1.25e-211	fatD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEDONB_00165	6.17e-212	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEDONB_00166	1.61e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCIEDONB_00167	5.02e-228	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HCIEDONB_00168	6.09e-57	fdxA	-	-	C	-	-	-	4Fe-4S binding domain
HCIEDONB_00169	4.18e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5316)
HCIEDONB_00170	2.13e-160	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEDONB_00171	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HCIEDONB_00173	0.0	hemG	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HCIEDONB_00174	1.36e-209	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HCIEDONB_00175	3.03e-208	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HCIEDONB_00176	1.06e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HCIEDONB_00177	4.85e-194	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCIEDONB_00178	2.06e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCIEDONB_00179	1.17e-220	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCIEDONB_00180	0.0	-	-	-	-	-	-	-	-
HCIEDONB_00181	1.1e-73	-	-	-	P	-	-	-	EamA-like transporter family
HCIEDONB_00182	7.44e-66	-	-	-	S	ko:K12962	ko01503,map01503	ko00000,ko00001,ko00002,ko01005,ko02000	EamA-like transporter family
HCIEDONB_00183	2.51e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HCIEDONB_00184	2.74e-46	csbA	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_00186	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCIEDONB_00187	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCIEDONB_00188	7.34e-95	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HCIEDONB_00189	8.19e-287	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HCIEDONB_00190	9.92e-184	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HCIEDONB_00191	1.07e-198	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCIEDONB_00192	5.63e-272	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCIEDONB_00193	0.0	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCIEDONB_00194	1.44e-186	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HCIEDONB_00195	1.17e-290	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HCIEDONB_00196	4.37e-224	yvlB	-	-	S	-	-	-	Putative adhesin
HCIEDONB_00197	2.84e-61	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HCIEDONB_00198	1.74e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCIEDONB_00199	3.87e-197	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCIEDONB_00200	1.2e-155	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HCIEDONB_00201	1.25e-114	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HCIEDONB_00202	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HCIEDONB_00203	2.68e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCIEDONB_00204	1.35e-111	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Nudix hydrolase
HCIEDONB_00205	2.87e-216	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HCIEDONB_00206	1.76e-232	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HCIEDONB_00207	6.78e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HCIEDONB_00208	6.85e-55	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HCIEDONB_00209	7.57e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCIEDONB_00211	7.17e-205	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_00212	2.16e-22	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_00213	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCIEDONB_00214	3.3e-39	B4168_3115	-	-	S	ko:K06419	-	ko00000	spore protein
HCIEDONB_00215	1.92e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCIEDONB_00216	3.47e-212	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HCIEDONB_00217	7.34e-293	-	-	-	HJ	-	-	-	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
HCIEDONB_00218	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HCIEDONB_00219	1.48e-271	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HCIEDONB_00220	0.0	-	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HCIEDONB_00221	3.57e-261	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HCIEDONB_00222	1.58e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HCIEDONB_00223	3.08e-207	yhaX	-	-	S	-	-	-	hydrolases of the HAD superfamily
HCIEDONB_00224	2.29e-179	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HCIEDONB_00225	7.99e-37	-	-	-	S	-	-	-	YhzD-like protein
HCIEDONB_00226	9.1e-165	-	-	-	P	-	-	-	Integral membrane protein TerC family
HCIEDONB_00228	1.5e-204	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
HCIEDONB_00229	3.2e-207	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
HCIEDONB_00230	1.64e-304	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HCIEDONB_00231	0.0	yhaN	-	-	L	-	-	-	AAA domain
HCIEDONB_00232	7.73e-230	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HCIEDONB_00233	2.41e-37	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HCIEDONB_00234	7.15e-198	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCIEDONB_00235	5.46e-14	-	-	-	-	-	-	-	-
HCIEDONB_00236	9.77e-71	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HCIEDONB_00237	8.28e-135	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HCIEDONB_00238	3.41e-47	yhaH	-	-	S	-	-	-	YtxH-like protein
HCIEDONB_00239	5.63e-108	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HCIEDONB_00240	4.71e-98	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HCIEDONB_00241	3.54e-177	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HCIEDONB_00242	1.1e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HCIEDONB_00243	1.07e-285	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HCIEDONB_00244	2.57e-309	yhfA	-	-	C	-	-	-	membrane
HCIEDONB_00245	1.12e-121	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HCIEDONB_00246	1.75e-256	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HCIEDONB_00247	8.07e-233	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HCIEDONB_00248	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HCIEDONB_00249	7.94e-134	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_00250	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HCIEDONB_00251	2.34e-224	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HCIEDONB_00252	4.6e-172	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HCIEDONB_00253	4.73e-15	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HCIEDONB_00254	6.84e-91	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HCIEDONB_00255	1.7e-211	-	-	-	EG	-	-	-	EamA-like transporter family
HCIEDONB_00256	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCIEDONB_00257	8.96e-134	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HCIEDONB_00258	2.58e-85	ytkA	-	-	S	-	-	-	YtkA-like
HCIEDONB_00259	1.07e-30	yhfH	-	-	S	-	-	-	YhfH-like protein
HCIEDONB_00260	4.71e-238	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HCIEDONB_00261	0.0	lcfB_2	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Activates fatty acids by binding to coenzyme A
HCIEDONB_00262	2.64e-153	ygaZ	-	-	E	-	-	-	AzlC protein
HCIEDONB_00263	1.11e-56	-	-	-	S	-	-	-	branched-chain amino acid
HCIEDONB_00264	2.52e-301	yhfN	-	-	O	-	-	-	Peptidase M48
HCIEDONB_00266	5.07e-125	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HCIEDONB_00267	4.3e-185	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HCIEDONB_00269	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HCIEDONB_00270	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HCIEDONB_00271	6.43e-41	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HCIEDONB_00272	8.26e-96	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HCIEDONB_00273	2.75e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HCIEDONB_00274	2.32e-144	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HCIEDONB_00275	1.44e-42	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HCIEDONB_00276	2.95e-285	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HCIEDONB_00277	1.41e-209	yisK	3.7.1.5	-	Q	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	ko00000,ko00001,ko01000	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HCIEDONB_00278	1.12e-78	yisL	-	-	S	-	-	-	UPF0344 protein
HCIEDONB_00279	1.68e-137	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HCIEDONB_00280	5.96e-206	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEDONB_00281	1.92e-204	yitS	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_00282	2.49e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HCIEDONB_00283	1.16e-199	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HCIEDONB_00284	1.14e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HCIEDONB_00285	2.94e-38	yjzC	-	-	S	-	-	-	YjzC-like protein
HCIEDONB_00286	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCIEDONB_00287	9.83e-186	-	-	-	GM	-	-	-	ADP-glyceromanno-heptose 6-epimerase activity
HCIEDONB_00289	3.78e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCIEDONB_00290	5.3e-303	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCIEDONB_00291	1.2e-196	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HCIEDONB_00292	9.27e-248	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCIEDONB_00293	4.46e-226	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCIEDONB_00294	1.22e-221	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEDONB_00295	5.05e-188	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
HCIEDONB_00296	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HCIEDONB_00297	1.07e-188	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HCIEDONB_00298	7.49e-236	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HCIEDONB_00299	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_00300	1.87e-65	-	-	-	S	-	-	-	Domain of unknown function (DUF3899)
HCIEDONB_00301	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HCIEDONB_00302	4.74e-197	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEDONB_00303	1.38e-231	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEDONB_00304	1.22e-248	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCIEDONB_00305	3.97e-227	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCIEDONB_00306	8.61e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCIEDONB_00307	5.92e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HCIEDONB_00308	1.58e-305	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HCIEDONB_00309	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HCIEDONB_00310	3.25e-09	-	-	-	-	-	-	-	-
HCIEDONB_00311	1.72e-207	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HCIEDONB_00312	1.66e-96	yjbI	-	-	S	ko:K06886	-	ko00000	COG2346 Truncated hemoglobins
HCIEDONB_00313	4.97e-160	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HCIEDONB_00314	4.92e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_00315	6.64e-82	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HCIEDONB_00316	4.66e-156	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HCIEDONB_00317	1.84e-196	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCIEDONB_00318	4.56e-210	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HCIEDONB_00319	7.35e-174	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HCIEDONB_00320	3.82e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HCIEDONB_00323	5.8e-110	-	-	-	S	ko:K06343,ko:K06344	-	ko00000	Spore coat protein
HCIEDONB_00324	9.04e-78	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HCIEDONB_00326	2.23e-102	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCIEDONB_00327	4.13e-109	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HCIEDONB_00328	5.76e-243	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HCIEDONB_00329	3.54e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HCIEDONB_00331	2.02e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HCIEDONB_00333	9.37e-96	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCIEDONB_00334	4.73e-123	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HCIEDONB_00335	1.56e-173	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HCIEDONB_00341	1.87e-214	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HCIEDONB_00342	4.1e-73	-	-	-	-	-	-	-	-
HCIEDONB_00343	4.6e-171	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HCIEDONB_00344	1.54e-217	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCIEDONB_00345	9.58e-271	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HCIEDONB_00346	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Papain family cysteine protease
HCIEDONB_00349	1.64e-283	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HCIEDONB_00350	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HCIEDONB_00351	3.2e-11	-	-	-	L	-	-	-	Transposase domain (DUF772)
HCIEDONB_00354	3.17e-91	-	-	-	S	ko:K09136	-	ko00000,ko03009	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HCIEDONB_00355	1.06e-41	-	-	-	C	-	-	-	Nitroreductase family
HCIEDONB_00359	1.64e-282	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HCIEDONB_00360	4.38e-102	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HCIEDONB_00361	3.72e-20	-	-	-	D	-	-	-	nuclear chromosome segregation
HCIEDONB_00362	1.04e-49	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HCIEDONB_00363	8.1e-36	-	-	-	-	-	-	-	-
HCIEDONB_00364	0.0	-	6.2.1.16	-	I	ko:K01907	ko00280,ko00650,map00280,map00650	ko00000,ko00001,ko01000,ko01004	AMP-dependent synthetase
HCIEDONB_00365	4.29e-119	-	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HCIEDONB_00366	4.16e-129	-	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HCIEDONB_00367	6.86e-108	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HCIEDONB_00368	1.14e-12	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HCIEDONB_00369	3.11e-99	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HCIEDONB_00370	1.79e-289	-	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HCIEDONB_00371	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_00372	1.14e-64	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HCIEDONB_00373	9.98e-77	-	-	-	N	-	-	-	domain, Protein
HCIEDONB_00374	4.19e-53	-	-	-	-	-	-	-	-
HCIEDONB_00377	4.03e-227	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HCIEDONB_00378	1.9e-231	gp17a	-	-	S	-	-	-	Mu-like prophage FluMu protein gp28
HCIEDONB_00379	3.91e-54	-	-	-	-	-	-	-	-
HCIEDONB_00381	2.07e-111	-	-	-	-	-	-	-	-
HCIEDONB_00383	2.49e-119	-	-	-	-	-	-	-	-
HCIEDONB_00384	7.4e-14	-	-	-	K	-	-	-	Helix-turn-helix
HCIEDONB_00385	3.51e-165	-	-	-	S	-	-	-	Family of unknown function (DUF5309)
HCIEDONB_00386	4.53e-44	-	-	-	-	-	-	-	-
HCIEDONB_00388	5.09e-40	-	-	-	-	-	-	-	-
HCIEDONB_00389	3.19e-130	-	-	-	N	-	-	-	COG3209 Rhs family protein
HCIEDONB_00390	3.14e-57	-	-	-	-	-	-	-	-
HCIEDONB_00391	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_00392	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_00394	1.27e-173	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase SAM-like domain
HCIEDONB_00396	4.66e-200	-	-	-	K	-	-	-	Sensory domain found in PocR
HCIEDONB_00397	9.59e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCIEDONB_00398	1.79e-268	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HCIEDONB_00399	9.07e-77	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_00400	5.58e-186	ldhA	1.1.1.28	-	CH	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HCIEDONB_00401	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
HCIEDONB_00403	1.08e-122	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HCIEDONB_00404	1.09e-221	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEDONB_00406	9.18e-63	-	-	-	-	-	-	-	-
HCIEDONB_00407	9.01e-178	-	4.1.1.77	-	Q	ko:K01617	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	COG3971 2-keto-4-pentenoate hydratase
HCIEDONB_00408	9.69e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HCIEDONB_00409	4.3e-297	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HCIEDONB_00410	2.42e-160	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HCIEDONB_00411	1.12e-99	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
HCIEDONB_00412	1.92e-237	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HCIEDONB_00413	6.2e-265	kinA	2.7.13.3	-	T	ko:K02491,ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCIEDONB_00414	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCIEDONB_00415	2.92e-108	-	-	-	-	-	-	-	-
HCIEDONB_00416	5.2e-184	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HCIEDONB_00417	2.87e-39	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HCIEDONB_00418	3.9e-27	-	-	-	S	-	-	-	Stage 0 Sporulation Regulatory protein
HCIEDONB_00420	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCIEDONB_00421	6.16e-109	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCIEDONB_00422	5.24e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HCIEDONB_00423	2.26e-06	-	-	-	S	ko:K06376	-	ko00000	Spo0E like sporulation regulatory protein
HCIEDONB_00424	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HCIEDONB_00425	3.38e-230	ykvI	-	-	S	-	-	-	membrane
HCIEDONB_00426	9.45e-138	-	-	-	S	ko:K07052	-	ko00000	Abortive infection protein
HCIEDONB_00427	6.02e-37	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_00428	2.45e-48	-	-	-	-	-	-	-	-
HCIEDONB_00429	2.6e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HCIEDONB_00430	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCIEDONB_00431	1.23e-179	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEDONB_00432	4.34e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HCIEDONB_00433	1.38e-272	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCIEDONB_00434	5.49e-207	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HCIEDONB_00435	1.02e-112	ykyB	-	-	S	-	-	-	YkyB-like protein
HCIEDONB_00436	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HCIEDONB_00437	0.0	-	-	-	T	-	-	-	Diguanylate cyclase
HCIEDONB_00438	9.15e-45	-	-	-	-	-	-	-	-
HCIEDONB_00439	1.01e-179	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEDONB_00440	5.57e-217	-	3.5.1.4	-	C	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Acetamidase
HCIEDONB_00441	7.13e-52	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_00442	7.02e-103	ykuL	-	-	S	-	-	-	CBS domain
HCIEDONB_00443	4.04e-203	ccpC	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_00444	2.06e-122	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCIEDONB_00445	2.59e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCIEDONB_00446	1.25e-26	-	-	-	S	-	-	-	YhfH-like protein
HCIEDONB_00447	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCIEDONB_00448	1.63e-39	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HCIEDONB_00449	3.06e-261	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCIEDONB_00450	2.48e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCIEDONB_00451	1.41e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCIEDONB_00452	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCIEDONB_00453	2.98e-45	-	-	-	-	-	-	-	-
HCIEDONB_00454	9.82e-09	-	-	-	S	-	-	-	SR1 protein
HCIEDONB_00455	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HCIEDONB_00457	2.12e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HCIEDONB_00458	2.85e-153	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HCIEDONB_00459	3.19e-33	-	-	-	-	-	-	-	-
HCIEDONB_00460	3.57e-194	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HCIEDONB_00461	1.1e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HCIEDONB_00462	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HCIEDONB_00463	2.12e-70	ylaH	-	-	S	-	-	-	YlaH-like protein
HCIEDONB_00464	0.0	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HCIEDONB_00465	1.87e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HCIEDONB_00466	1.4e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HCIEDONB_00467	1.55e-275	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HCIEDONB_00468	3.65e-224	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HCIEDONB_00469	1.21e-212	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HCIEDONB_00470	3.71e-261	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HCIEDONB_00471	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HCIEDONB_00472	2.95e-147	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HCIEDONB_00473	1.39e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HCIEDONB_00474	5.83e-225	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HCIEDONB_00475	9.34e-85	ylbA	-	-	S	-	-	-	YugN-like family
HCIEDONB_00476	3e-251	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HCIEDONB_00477	6.59e-111	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein, possibly involved in aromatic compounds catabolism
HCIEDONB_00478	5e-92	ylbD	-	-	S	-	-	-	Putative coat protein
HCIEDONB_00479	5.16e-50	ylbE	-	-	S	-	-	-	YlbE-like protein
HCIEDONB_00480	6.19e-86	-	-	-	-	-	-	-	-
HCIEDONB_00481	3.1e-96	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HCIEDONB_00482	7.56e-62	ylbG	-	-	S	-	-	-	UPF0298 protein
HCIEDONB_00483	7.42e-89	-	-	-	S	-	-	-	Methylthioribose kinase
HCIEDONB_00484	4.06e-140	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HCIEDONB_00485	6.3e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCIEDONB_00486	2.23e-280	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HCIEDONB_00487	1.43e-179	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HCIEDONB_00488	1.77e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HCIEDONB_00489	1.07e-304	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HCIEDONB_00490	1.06e-124	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HCIEDONB_00491	7.12e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HCIEDONB_00492	7.2e-109	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HCIEDONB_00493	1.12e-119	ylbP	-	-	K	-	-	-	n-acetyltransferase
HCIEDONB_00494	2.95e-207	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCIEDONB_00495	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HCIEDONB_00496	1.96e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HCIEDONB_00497	4.43e-222	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCIEDONB_00498	1.18e-69	ftsL	-	-	D	-	-	-	Essential cell division protein
HCIEDONB_00499	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HCIEDONB_00500	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HCIEDONB_00501	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCIEDONB_00502	6.04e-103	-	-	-	M	-	-	-	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HCIEDONB_00503	2.75e-219	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCIEDONB_00504	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCIEDONB_00505	2.87e-249	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HCIEDONB_00506	9.87e-262	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCIEDONB_00507	1.19e-156	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCIEDONB_00508	5.19e-174	-	-	-	L	-	-	-	PFAM Transposase, Mutator
HCIEDONB_00509	5.93e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCIEDONB_00510	1.59e-247	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCIEDONB_00511	8.88e-217	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HCIEDONB_00512	5.54e-156	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEDONB_00513	7.67e-177	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEDONB_00514	2.63e-58	ylmC	-	-	S	-	-	-	sporulation protein
HCIEDONB_00515	2.47e-113	-	-	-	M	-	-	-	3D domain
HCIEDONB_00516	3.47e-206	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HCIEDONB_00517	1.97e-158	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HCIEDONB_00518	2.44e-99	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCIEDONB_00519	3e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HCIEDONB_00520	6.37e-185	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HCIEDONB_00521	1.73e-96	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HCIEDONB_00522	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCIEDONB_00524	3.89e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCIEDONB_00525	1.18e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCIEDONB_00526	2.2e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCIEDONB_00527	3.89e-211	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HCIEDONB_00528	2.97e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCIEDONB_00529	1.36e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HCIEDONB_00530	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HCIEDONB_00531	1.18e-180	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HCIEDONB_00532	6.86e-229	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCIEDONB_00533	1.14e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCIEDONB_00534	1.45e-144	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCIEDONB_00535	3.19e-157	-	-	-	S	-	-	-	Nuclease-related domain
HCIEDONB_00536	2.17e-266	-	-	-	L	-	-	-	Transposase IS4 family protein
HCIEDONB_00537	2.19e-215	-	-	-	K	-	-	-	AraC-like ligand binding domain
HCIEDONB_00538	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HCIEDONB_00539	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HCIEDONB_00540	2.74e-205	rhaD	4.1.2.19	-	G	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HCIEDONB_00541	2.72e-42	fucO	1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K13954,ko:K17067	ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00640,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00640,map00680,map01100,map01110,map01120,map01130,map01200,map01220	ko00000,ko00001,ko01000	hydroxyacid-oxoacid transhydrogenase activity
HCIEDONB_00542	8.38e-98	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HCIEDONB_00543	7.33e-135	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCIEDONB_00544	7.13e-311	-	-	-	EGP	-	-	-	Major facilitator superfamily
HCIEDONB_00545	0.0	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HCIEDONB_00546	2.57e-128	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HCIEDONB_00547	1.39e-134	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCIEDONB_00548	1.4e-245	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HCIEDONB_00549	1.41e-206	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
HCIEDONB_00550	0.0	-	-	-	S	ko:K07077	-	ko00000	FAD binding domain
HCIEDONB_00551	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HCIEDONB_00552	8.15e-94	-	-	-	L	ko:K07499	-	ko00000	Transposase
HCIEDONB_00553	1.02e-13	-	-	-	L	ko:K07494	-	ko00000	DDE superfamily endonuclease
HCIEDONB_00554	2.03e-116	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HCIEDONB_00555	8.75e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HCIEDONB_00556	1.2e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HCIEDONB_00558	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HCIEDONB_00559	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HCIEDONB_00560	8.39e-200	yloC	-	-	S	-	-	-	stress-induced protein
HCIEDONB_00561	1.83e-60	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HCIEDONB_00562	2.24e-140	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HCIEDONB_00563	4e-40	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCIEDONB_00564	2.01e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCIEDONB_00565	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCIEDONB_00566	4.09e-106	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCIEDONB_00567	2.69e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCIEDONB_00568	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCIEDONB_00569	1.1e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HCIEDONB_00570	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HCIEDONB_00571	1.47e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCIEDONB_00572	6.41e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HCIEDONB_00573	5.94e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HCIEDONB_00574	1.22e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HCIEDONB_00575	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_00576	1.27e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_00577	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HCIEDONB_00578	2.05e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HCIEDONB_00579	1.56e-199	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HCIEDONB_00580	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCIEDONB_00581	2.08e-126	fapR	-	-	Q	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HCIEDONB_00582	6.2e-264	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCIEDONB_00583	1.24e-209	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
HCIEDONB_00584	1.04e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HCIEDONB_00585	1.64e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCIEDONB_00586	2.2e-170	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCIEDONB_00587	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HCIEDONB_00588	2.69e-230	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCIEDONB_00589	4.33e-69	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCIEDONB_00590	1.81e-309	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCIEDONB_00591	5.58e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HCIEDONB_00592	1.76e-47	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HCIEDONB_00593	1.68e-81	-	-	-	S	-	-	-	YlqD protein
HCIEDONB_00594	4.35e-120	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCIEDONB_00595	1.15e-180	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HCIEDONB_00596	6.22e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCIEDONB_00597	9.01e-132	sipS	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HCIEDONB_00598	2.33e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCIEDONB_00599	2.21e-179	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCIEDONB_00600	2.46e-288	-	-	-	D	-	-	-	nuclear chromosome segregation
HCIEDONB_00601	3.12e-61	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HCIEDONB_00602	5.38e-271	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HCIEDONB_00603	1.08e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HCIEDONB_00604	1.53e-209	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HCIEDONB_00605	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCIEDONB_00606	1.37e-216	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HCIEDONB_00607	3.26e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCIEDONB_00608	1.01e-298	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCIEDONB_00609	1.32e-173	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HCIEDONB_00610	9.37e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HCIEDONB_00611	1.41e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HCIEDONB_00612	1.88e-54	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body complex protein FliE
HCIEDONB_00613	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HCIEDONB_00614	2.06e-216	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HCIEDONB_00615	1e-168	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HCIEDONB_00616	1.79e-315	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HCIEDONB_00617	2.11e-93	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HCIEDONB_00618	1.55e-84	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HCIEDONB_00619	0.0	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control
HCIEDONB_00620	1.94e-137	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Required for flagellar hook formation. May act as a scaffolding protein
HCIEDONB_00621	3.59e-102	flg	-	-	N	-	-	-	Putative flagellar
HCIEDONB_00622	1.55e-174	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HCIEDONB_00623	4.65e-86	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HCIEDONB_00624	6.39e-234	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HCIEDONB_00625	3.36e-249	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HCIEDONB_00626	2.57e-78	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HCIEDONB_00627	3.93e-150	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HCIEDONB_00628	1.16e-139	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HCIEDONB_00629	3.82e-52	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HCIEDONB_00630	5.99e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HCIEDONB_00631	2.15e-241	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HCIEDONB_00632	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HCIEDONB_00633	3.88e-263	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HCIEDONB_00634	2.83e-202	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HCIEDONB_00635	2.22e-152	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HCIEDONB_00636	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HCIEDONB_00637	2.9e-90	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HCIEDONB_00638	1.34e-145	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HCIEDONB_00639	2.35e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HCIEDONB_00640	3.37e-175	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEDONB_00641	7.3e-112	ylxL	-	-	-	-	-	-	-
HCIEDONB_00642	1.05e-175	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HCIEDONB_00643	2.14e-201	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCIEDONB_00644	2.67e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HCIEDONB_00645	3.09e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCIEDONB_00646	5.46e-189	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCIEDONB_00647	7.71e-186	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HCIEDONB_00648	5.08e-262	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HCIEDONB_00649	9.48e-300	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HCIEDONB_00650	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCIEDONB_00651	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCIEDONB_00652	2.23e-107	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HCIEDONB_00653	1.72e-285	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HCIEDONB_00654	2.27e-59	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HCIEDONB_00655	2.13e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
HCIEDONB_00656	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCIEDONB_00657	4.54e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HCIEDONB_00658	6.7e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCIEDONB_00659	7.07e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCIEDONB_00660	6.65e-234	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HCIEDONB_00661	5e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCIEDONB_00662	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HCIEDONB_00663	1.41e-266	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HCIEDONB_00664	1.06e-297	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HCIEDONB_00665	2.52e-51	ymxH	-	-	S	-	-	-	YlmC YmxH family
HCIEDONB_00666	4.38e-243	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HCIEDONB_00667	2.17e-141	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HCIEDONB_00668	8.48e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCIEDONB_00669	2.86e-287	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HCIEDONB_00670	2.83e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCIEDONB_00671	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCIEDONB_00672	1.18e-169	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HCIEDONB_00673	4.69e-47	-	-	-	S	-	-	-	YlzJ-like protein
HCIEDONB_00674	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HCIEDONB_00675	1.43e-252	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HCIEDONB_00676	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCIEDONB_00677	3.06e-239	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HCIEDONB_00678	3.76e-219	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HCIEDONB_00679	4.38e-303	albE	-	-	S	-	-	-	Peptidase M16
HCIEDONB_00680	4.28e-312	ymfH	-	-	S	-	-	-	zinc protease
HCIEDONB_00681	2.69e-186	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HCIEDONB_00682	2.25e-54	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HCIEDONB_00683	5.9e-188	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HCIEDONB_00684	1.15e-212	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HCIEDONB_00685	1.53e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCIEDONB_00686	5.38e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HCIEDONB_00687	1.53e-243	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCIEDONB_00688	1.41e-304	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HCIEDONB_00689	1.02e-194	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HCIEDONB_00690	1.21e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HCIEDONB_00691	8.92e-219	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HCIEDONB_00692	1.05e-314	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HCIEDONB_00693	2.31e-267	-	-	-	E	ko:K14052	-	ko00000,ko02000	Amino acid permease
HCIEDONB_00694	0.0	-	-	-	KT	-	-	-	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HCIEDONB_00695	0.0	-	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HCIEDONB_00696	0.0	-	2.6.1.82	-	E	ko:K09251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCIEDONB_00697	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HCIEDONB_00698	1.8e-84	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HCIEDONB_00699	4.31e-128	-	-	-	S	ko:K06328	-	ko00000	Outer spore coat protein E (CotE)
HCIEDONB_00700	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCIEDONB_00701	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCIEDONB_00702	3.69e-54	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HCIEDONB_00703	7.59e-31	-	-	-	S	-	-	-	protein secretion by the type IV secretion system
HCIEDONB_00705	9e-08	-	-	-	-	-	-	-	-
HCIEDONB_00706	3.36e-248	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCIEDONB_00707	1.4e-48	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HCIEDONB_00709	4.44e-224	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HCIEDONB_00710	3.13e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCIEDONB_00711	7.1e-313	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HCIEDONB_00712	6.27e-217	ypcP	-	-	L	-	-	-	5'3' exonuclease
HCIEDONB_00714	1.59e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
HCIEDONB_00715	4.69e-43	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HCIEDONB_00716	3.17e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HCIEDONB_00717	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HCIEDONB_00718	3.21e-110	-	-	-	-	-	-	-	-
HCIEDONB_00719	3.18e-155	ypgQ	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HCIEDONB_00720	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HCIEDONB_00721	4.7e-220	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HCIEDONB_00722	2.03e-96	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HCIEDONB_00723	9.63e-136	ypjP	-	-	S	-	-	-	YpjP-like protein
HCIEDONB_00724	3.07e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCIEDONB_00725	2.38e-119	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCIEDONB_00726	7.44e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HCIEDONB_00727	3.38e-179	-	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related esterases
HCIEDONB_00728	3.38e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_00729	0.0	rsmF	-	-	J	-	-	-	RNA-binding PUA-like domain of methyltransferase RsmF
HCIEDONB_00730	3.7e-133	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCIEDONB_00731	5.45e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HCIEDONB_00732	1.66e-25	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HCIEDONB_00733	1.08e-308	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	CHASE3 domain
HCIEDONB_00734	2.13e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HCIEDONB_00735	4.5e-149	yodN	-	-	-	-	-	-	-
HCIEDONB_00736	1.12e-33	yozD	-	-	S	-	-	-	YozD-like protein
HCIEDONB_00738	1.34e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HCIEDONB_00739	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HCIEDONB_00740	3.48e-88	ypoP	-	-	K	-	-	-	transcriptional
HCIEDONB_00741	5.42e-150	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HCIEDONB_00742	2.75e-316	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HCIEDONB_00744	5.31e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCIEDONB_00745	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HCIEDONB_00746	5.34e-182	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HCIEDONB_00747	1.48e-137	pap2c	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HCIEDONB_00749	0.0	yfnI	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HCIEDONB_00750	1.54e-135	laaE	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_00751	1.69e-77	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
HCIEDONB_00752	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HCIEDONB_00753	2.88e-290	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HCIEDONB_00754	5.43e-157	csrR	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEDONB_00755	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCIEDONB_00756	3.9e-105	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HCIEDONB_00757	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HCIEDONB_00758	7.32e-270	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HCIEDONB_00759	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HCIEDONB_00760	8.87e-120	rok	-	-	S	-	-	-	Repressor of ComK
HCIEDONB_00761	5.55e-154	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCIEDONB_00763	6.68e-206	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HCIEDONB_00764	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCIEDONB_00765	3.34e-245	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HCIEDONB_00766	4.17e-164	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HCIEDONB_00767	1.59e-136	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Proton-coupled thiamine transporter YuaJ
HCIEDONB_00768	2.45e-211	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HCIEDONB_00769	8.76e-104	-	-	-	S	-	-	-	Domain in cystathionine beta-synthase and other proteins.
HCIEDONB_00770	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HCIEDONB_00771	5.18e-139	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HCIEDONB_00772	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCIEDONB_00773	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HCIEDONB_00774	1.99e-146	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HCIEDONB_00775	1.45e-230	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HCIEDONB_00776	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
HCIEDONB_00777	2.7e-91	-	-	-	S	-	-	-	CHY zinc finger
HCIEDONB_00778	1.42e-269	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HCIEDONB_00779	9.1e-141	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HCIEDONB_00780	2.26e-286	hisD	1.1.1.23, 1.1.1.308	-	E	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCIEDONB_00781	4.74e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HCIEDONB_00782	9.55e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCIEDONB_00783	9.01e-164	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HCIEDONB_00784	7.72e-179	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCIEDONB_00785	4e-156	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HCIEDONB_00786	2.08e-54	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
HCIEDONB_00787	5.13e-309	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
HCIEDONB_00788	4.98e-223	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HCIEDONB_00789	7.49e-283	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
HCIEDONB_00790	3.99e-158	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HCIEDONB_00791	1.62e-174	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HCIEDONB_00792	6.33e-49	-	-	-	-	-	-	-	-
HCIEDONB_00793	1.42e-62	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
HCIEDONB_00794	6.56e-273	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HCIEDONB_00795	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HCIEDONB_00796	1.07e-44	-	-	-	S	-	-	-	ATP synthase, subunit b
HCIEDONB_00797	2.61e-132	msrA	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCIEDONB_00799	1.15e-43	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HCIEDONB_00800	1.7e-154	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HCIEDONB_00801	6.01e-217	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HCIEDONB_00802	7.1e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF1292)
HCIEDONB_00803	1.41e-63	yxiS	-	-	-	-	-	-	-
HCIEDONB_00804	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HCIEDONB_00805	4.63e-175	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HCIEDONB_00806	1.62e-232	bceS	2.7.13.3	-	T	ko:K11629	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HCIEDONB_00807	1.39e-165	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEDONB_00808	4.93e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1672)
HCIEDONB_00810	0.0	-	-	-	-	-	-	-	-
HCIEDONB_00811	2.11e-22	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_00812	1.24e-94	-	-	-	K	-	-	-	Helix-turn-helix domain
HCIEDONB_00813	5.19e-257	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HCIEDONB_00814	5.83e-251	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HCIEDONB_00815	3.71e-24	-	-	-	-	-	-	-	-
HCIEDONB_00816	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HCIEDONB_00817	1.24e-258	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HCIEDONB_00818	4.68e-194	-	-	-	-	-	-	-	-
HCIEDONB_00821	1.73e-304	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HCIEDONB_00822	4.07e-72	-	-	-	S	ko:K13628,ko:K15724	-	ko00000,ko03016	Heme biosynthesis protein HemY
HCIEDONB_00823	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HCIEDONB_00824	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HCIEDONB_00825	5.78e-57	-	-	-	S	-	-	-	Small, acid-soluble spore proteins, alpha/beta type
HCIEDONB_00826	4.43e-82	-	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
HCIEDONB_00827	6.2e-142	-	-	-	M	-	-	-	effector of murein hydrolase
HCIEDONB_00828	0.0	alkK	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCIEDONB_00829	3.9e-149	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	lytic transglycosylase activity
HCIEDONB_00830	5.89e-33	ydaS	-	-	S	-	-	-	membrane
HCIEDONB_00831	1.14e-26	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HCIEDONB_00832	5.79e-52	-	-	-	-	-	-	-	-
HCIEDONB_00833	5.12e-306	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HCIEDONB_00834	3.51e-26	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HCIEDONB_00835	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HCIEDONB_00836	1.76e-06	-	-	-	S	-	-	-	Fur-regulated basic protein B
HCIEDONB_00837	4.72e-28	sspN	-	-	S	ko:K06431	-	ko00000	Small acid-soluble spore protein N family
HCIEDONB_00838	1.26e-42	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HCIEDONB_00839	1.91e-98	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HCIEDONB_00840	1.69e-69	yneQ	-	-	-	-	-	-	-
HCIEDONB_00841	1.65e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HCIEDONB_00842	2.15e-131	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCIEDONB_00843	3.06e-94	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HCIEDONB_00844	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCIEDONB_00845	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCIEDONB_00846	1.69e-185	-	-	-	-	-	-	-	-
HCIEDONB_00847	2.47e-270	-	-	-	G	-	-	-	Major facilitator superfamily
HCIEDONB_00848	1.97e-191	-	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCIEDONB_00849	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HCIEDONB_00850	1.07e-90	-	-	-	E	-	-	-	Glyoxalase
HCIEDONB_00851	1.28e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4023)
HCIEDONB_00855	2.79e-254	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HCIEDONB_00857	1.75e-133	-	-	-	S	-	-	-	oxidoreductase activity
HCIEDONB_00858	5.69e-122	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HCIEDONB_00860	3.06e-262	icd	1.1.1.41, 1.1.1.42, 1.1.1.85	-	CE	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HCIEDONB_00861	2.17e-205	-	-	-	S	-	-	-	Methyltransferase domain
HCIEDONB_00865	1.39e-178	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HCIEDONB_00866	5.05e-121	yvbK	-	-	K	-	-	-	acetyltransferase
HCIEDONB_00867	6.79e-120	-	-	-	J	-	-	-	acetyltransferase
HCIEDONB_00868	7.96e-91	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HCIEDONB_00869	4.77e-100	-	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
HCIEDONB_00870	6.52e-63	-	-	-	F	-	-	-	nucleoside 2-deoxyribosyltransferase
HCIEDONB_00871	1.14e-145	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCIEDONB_00872	9.98e-87	-	-	-	Q	-	-	-	methyltransferase
HCIEDONB_00873	1.99e-158	-	2.5.1.2	-	M	ko:K10811	ko00730,map00730	ko00000,ko00001,ko01000	transport
HCIEDONB_00874	8.39e-314	thiP	-	-	F	-	-	-	Permease for cytosine/purines, uracil, thiamine, allantoin
HCIEDONB_00875	3.69e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HCIEDONB_00876	7.41e-177	fabG5	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HCIEDONB_00877	6.89e-170	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCIEDONB_00878	1.01e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HCIEDONB_00879	1.34e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCIEDONB_00880	6.67e-158	yflK	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_00881	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HCIEDONB_00882	1.62e-57	-	-	-	-	-	-	-	-
HCIEDONB_00884	9.48e-108	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HCIEDONB_00886	1.88e-273	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCIEDONB_00887	4.18e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCIEDONB_00888	8.58e-250	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
HCIEDONB_00889	6.85e-178	ssuC	-	-	P	ko:K15599	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
HCIEDONB_00890	2.94e-237	-	-	-	P	ko:K02051,ko:K15598	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HCIEDONB_00891	1.87e-97	-	-	-	S	ko:K06991	-	ko00000	Glyoxalase bleomycin resistance protein dioxygenase
HCIEDONB_00892	7.71e-183	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
HCIEDONB_00893	1.78e-164	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
HCIEDONB_00894	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HCIEDONB_00895	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HCIEDONB_00896	1.31e-141	-	-	-	-	-	-	-	-
HCIEDONB_00897	4.29e-173	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HCIEDONB_00898	0.0	dapE	-	-	E	-	-	-	Peptidase dimerisation domain
HCIEDONB_00899	3.5e-224	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HCIEDONB_00900	6.98e-241	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCIEDONB_00901	2.64e-242	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCIEDONB_00902	6.89e-278	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCIEDONB_00903	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCIEDONB_00904	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HCIEDONB_00905	9.18e-243	-	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	Mechanosensitive ion channel
HCIEDONB_00906	2.64e-246	-	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HCIEDONB_00907	3.11e-73	-	-	-	I	-	-	-	SCP-2 sterol transfer family
HCIEDONB_00908	1.32e-219	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HCIEDONB_00909	1.8e-129	ymdB	-	-	S	-	-	-	Appr-1'-p processing enzyme
HCIEDONB_00910	1.65e-35	sspH	-	-	S	ko:K06425	-	ko00000	small acid-soluble spore protein
HCIEDONB_00911	5.17e-175	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEDONB_00912	3.07e-264	-	2.3.1.16, 2.3.1.9	-	I	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HCIEDONB_00913	0.0	-	6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCIEDONB_00914	1.16e-81	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HCIEDONB_00915	4.01e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HCIEDONB_00916	2.03e-125	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HCIEDONB_00917	1.83e-79	-	-	-	-	-	-	-	-
HCIEDONB_00918	3.38e-104	-	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCIEDONB_00919	1.9e-232	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HCIEDONB_00920	5.19e-170	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HCIEDONB_00921	3.14e-275	-	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HCIEDONB_00922	1.28e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HCIEDONB_00923	1.99e-189	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HCIEDONB_00924	5.92e-201	-	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HCIEDONB_00925	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HCIEDONB_00926	1.68e-254	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
HCIEDONB_00927	2.8e-277	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCIEDONB_00928	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCIEDONB_00929	1.32e-250	-	-	-	G	ko:K07190	ko04020,ko04910,ko04922,map04020,map04910,map04922	ko00000,ko00001	Glycosyl hydrolases family 15
HCIEDONB_00931	1.19e-31	-	-	-	S	-	-	-	YpzG-like protein
HCIEDONB_00932	5.98e-116	-	-	-	Q	-	-	-	protein disulfide oxidoreductase activity
HCIEDONB_00933	3.08e-123	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HCIEDONB_00935	3.46e-155	XK27_06885	-	-	L	-	-	-	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HCIEDONB_00936	5.39e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HCIEDONB_00937	1.03e-100	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
HCIEDONB_00938	2.41e-106	-	-	-	V	-	-	-	VanZ like family
HCIEDONB_00939	3.76e-217	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HCIEDONB_00940	6.27e-219	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCIEDONB_00941	1.87e-74	-	-	-	-	-	-	-	-
HCIEDONB_00942	6.74e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HCIEDONB_00943	1.52e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HCIEDONB_00944	5.09e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1450)
HCIEDONB_00945	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCIEDONB_00946	3.34e-92	-	-	-	I	-	-	-	MaoC like domain
HCIEDONB_00947	1.59e-104	-	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HCIEDONB_00948	1.29e-198	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HCIEDONB_00949	1.58e-34	dld	1.1.2.4	-	C	ko:K00102	ko00620,map00620	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HCIEDONB_00950	3.69e-282	dld	1.1.2.4	-	C	ko:K00102	ko00620,map00620	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HCIEDONB_00952	1.97e-256	selU	-	-	S	ko:K06917	-	ko00000,ko01000,ko03016	tRNA 2-selenouridine synthase
HCIEDONB_00953	4.42e-249	selD	2.7.9.3	-	E	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	Synthesizes selenophosphate from selenide and ATP
HCIEDONB_00954	3.42e-175	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HCIEDONB_00955	4.41e-247	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
HCIEDONB_00956	7.11e-293	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCIEDONB_00957	4.84e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCIEDONB_00958	1.52e-93	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HCIEDONB_00959	2.59e-277	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HCIEDONB_00960	4.44e-295	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
HCIEDONB_00961	8.07e-164	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCIEDONB_00962	2.55e-166	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HCIEDONB_00963	2.53e-67	tnrA	-	-	K	-	-	-	transcriptional
HCIEDONB_00964	3.93e-140	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCIEDONB_00965	3.77e-32	-	-	-	S	-	-	-	Virus attachment protein p12 family
HCIEDONB_00966	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HCIEDONB_00967	1.97e-63	-	-	-	P	ko:K04758	-	ko00000,ko02000	COG1918 Fe2 transport system protein A
HCIEDONB_00968	4.4e-290	-	2.6.1.83	-	E	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCIEDONB_00969	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HCIEDONB_00970	2.21e-295	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCIEDONB_00971	1.89e-227	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCIEDONB_00972	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HCIEDONB_00973	1.12e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HCIEDONB_00974	4.74e-287	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HCIEDONB_00975	8.33e-183	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HCIEDONB_00976	1.11e-299	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HCIEDONB_00977	6.35e-256	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HCIEDONB_00979	3.71e-105	-	-	-	-	-	-	-	-
HCIEDONB_00980	2.42e-197	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
HCIEDONB_00981	1.02e-112	-	-	-	-	-	-	-	-
HCIEDONB_00982	2.54e-42	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HCIEDONB_00984	2.2e-224	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HCIEDONB_00985	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HCIEDONB_00986	1.36e-136	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HCIEDONB_00987	9.17e-100	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HCIEDONB_00988	1.09e-100	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HCIEDONB_00989	1.96e-77	yneI	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HCIEDONB_00990	1.01e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HCIEDONB_00991	1.25e-38	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HCIEDONB_00992	2.67e-101	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HCIEDONB_00993	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCIEDONB_00994	5.7e-44	ynzC	-	-	S	-	-	-	UPF0291 protein
HCIEDONB_00995	3.69e-150	yneB	-	-	L	-	-	-	resolvase
HCIEDONB_00996	1.94e-76	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HCIEDONB_00997	3.86e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCIEDONB_00998	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HCIEDONB_00999	1.01e-86	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HCIEDONB_01000	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HCIEDONB_01001	3.54e-47	-	-	-	-	-	-	-	-
HCIEDONB_01002	4.41e-169	-	-	-	O	-	-	-	prohibitin homologues
HCIEDONB_01003	4.36e-46	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
HCIEDONB_01004	3.44e-212	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
HCIEDONB_01005	2.74e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCIEDONB_01006	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HCIEDONB_01007	3.3e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HCIEDONB_01008	2.07e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCIEDONB_01009	1.56e-132	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HCIEDONB_01010	2.98e-62	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
HCIEDONB_01011	0.0	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HCIEDONB_01012	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HCIEDONB_01013	3.62e-100	hspc4-1	-	-	O	-	-	-	Belongs to the small heat shock protein (HSP20) family
HCIEDONB_01014	3.92e-110	yppG	-	-	S	-	-	-	YppG-like protein
HCIEDONB_01015	1.13e-81	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
HCIEDONB_01019	1.65e-145	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCIEDONB_01020	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HCIEDONB_01021	1.07e-159	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCIEDONB_01022	5.25e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HCIEDONB_01023	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HCIEDONB_01024	7.45e-278	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HCIEDONB_01025	6.71e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_01026	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HCIEDONB_01027	8.4e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HCIEDONB_01028	1.84e-203	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HCIEDONB_01029	8.05e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HCIEDONB_01030	9.42e-232	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCIEDONB_01031	1.42e-289	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCIEDONB_01032	9.14e-283	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HCIEDONB_01033	3.29e-171	ypjG	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HCIEDONB_01034	1.15e-191	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCIEDONB_01035	3.2e-76	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HCIEDONB_01036	3.32e-206	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HCIEDONB_01037	1.88e-106	queT	-	-	S	-	-	-	QueT transporter
HCIEDONB_01038	3.83e-137	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HCIEDONB_01039	5.43e-184	ypjB	-	-	S	-	-	-	sporulation protein
HCIEDONB_01040	2.97e-142	ypjA	-	-	S	-	-	-	membrane
HCIEDONB_01041	1.52e-190	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HCIEDONB_01042	2.94e-164	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HCIEDONB_01043	5.32e-129	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HCIEDONB_01044	1.46e-111	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HCIEDONB_01045	3.68e-130	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HCIEDONB_01046	2.54e-305	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HCIEDONB_01047	4.07e-305	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCIEDONB_01048	3.72e-261	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HCIEDONB_01049	1.79e-267	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HCIEDONB_01050	6.31e-79	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HCIEDONB_01051	8.11e-262	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HCIEDONB_01052	4e-279	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HCIEDONB_01053	4.49e-187	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HCIEDONB_01054	4.75e-101	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HCIEDONB_01055	1.32e-224	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HCIEDONB_01056	1.1e-164	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HCIEDONB_01057	2.12e-184	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HCIEDONB_01058	1.85e-44	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HCIEDONB_01059	1.54e-56	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCIEDONB_01060	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HCIEDONB_01061	1.7e-175	yphF	-	-	-	-	-	-	-
HCIEDONB_01062	7.83e-13	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HCIEDONB_01063	7.9e-246	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HCIEDONB_01064	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HCIEDONB_01065	2.35e-13	yphA	-	-	-	-	-	-	-
HCIEDONB_01066	9.95e-21	-	-	-	S	-	-	-	YpzI-like protein
HCIEDONB_01067	2.71e-260	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HCIEDONB_01068	2.98e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HCIEDONB_01069	1.84e-153	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HCIEDONB_01070	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HCIEDONB_01071	4.17e-193	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HCIEDONB_01072	4.87e-164	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HCIEDONB_01073	2.85e-243	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HCIEDONB_01074	2.28e-310	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HCIEDONB_01075	7.27e-145	-	-	-	NOT	ko:K16511	-	ko00000	Negative regulator of genetic competence (MecA)
HCIEDONB_01076	5.66e-184	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HCIEDONB_01077	8.41e-54	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HCIEDONB_01078	1.24e-60	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HCIEDONB_01079	2.19e-135	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HCIEDONB_01080	1.47e-104	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HCIEDONB_01082	7.6e-133	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HCIEDONB_01083	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HCIEDONB_01084	2.83e-261	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HCIEDONB_01085	1.69e-54	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HCIEDONB_01086	1.58e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCIEDONB_01087	1.29e-174	-	-	-	M	-	-	-	COG0739 Membrane proteins related to metalloendopeptidases
HCIEDONB_01088	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCIEDONB_01089	2.06e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEDONB_01090	2.11e-292	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HCIEDONB_01091	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HCIEDONB_01092	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HCIEDONB_01093	5.38e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HCIEDONB_01094	3.96e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HCIEDONB_01095	1.94e-124	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HCIEDONB_01096	1.37e-271	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HCIEDONB_01097	7.85e-139	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCIEDONB_01098	5.61e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCIEDONB_01099	1.13e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HCIEDONB_01100	1.28e-82	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCIEDONB_01101	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCIEDONB_01102	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HCIEDONB_01103	2.47e-137	spoVAEA	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
HCIEDONB_01104	1.75e-95	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
HCIEDONB_01105	4.9e-145	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HCIEDONB_01106	8.59e-171	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEDONB_01107	8.55e-99	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HCIEDONB_01108	4.34e-75	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HCIEDONB_01109	2.58e-274	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HCIEDONB_01110	8.9e-216	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HCIEDONB_01111	2.06e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HCIEDONB_01112	1.5e-111	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HCIEDONB_01113	1.09e-136	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HCIEDONB_01114	5.16e-292	yqxK	-	-	L	-	-	-	DNA helicase
HCIEDONB_01115	2.68e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HCIEDONB_01116	9.85e-08	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HCIEDONB_01117	1.52e-210	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HCIEDONB_01118	1.86e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HCIEDONB_01120	2.78e-140	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HCIEDONB_01121	5.35e-270	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HCIEDONB_01122	2.21e-225	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HCIEDONB_01123	1.82e-311	yaaH_2	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HCIEDONB_01124	1.17e-73	yqiX	-	-	S	-	-	-	YolD-like protein
HCIEDONB_01125	4.05e-306	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCIEDONB_01126	4.46e-184	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEDONB_01127	1.86e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCIEDONB_01128	1.32e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCIEDONB_01129	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCIEDONB_01130	7.08e-292	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCIEDONB_01131	1.04e-102	-	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HCIEDONB_01132	1.76e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HCIEDONB_01133	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_01134	1.86e-123	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_01135	4.43e-100	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HCIEDONB_01136	3.74e-211	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HCIEDONB_01137	8.54e-275	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCIEDONB_01138	6.64e-233	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCIEDONB_01139	9.84e-236	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCIEDONB_01140	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCIEDONB_01141	1.53e-265	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HCIEDONB_01142	1.39e-64	-	-	-	T	-	-	-	transcription factor binding
HCIEDONB_01143	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HCIEDONB_01144	7.59e-48	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HCIEDONB_01145	1.1e-175	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HCIEDONB_01146	3.14e-182	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HCIEDONB_01148	6.03e-307	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HCIEDONB_01149	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HCIEDONB_01150	2.26e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HCIEDONB_01151	4.13e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HCIEDONB_01152	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCIEDONB_01153	1.52e-203	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HCIEDONB_01154	4.77e-42	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCIEDONB_01155	5.25e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCIEDONB_01156	3.88e-203	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCIEDONB_01157	3.5e-84	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCIEDONB_01158	7.54e-90	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_01159	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HCIEDONB_01160	2.67e-106	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCIEDONB_01161	1.12e-110	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HCIEDONB_01162	1.55e-142	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HCIEDONB_01163	2.58e-139	spoIIIAF	-	-	S	ko:K06395	-	ko00000	stage III sporulation protein AF
HCIEDONB_01164	2.12e-258	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HCIEDONB_01165	2.48e-78	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HCIEDONB_01166	3.6e-38	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HCIEDONB_01167	4.88e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HCIEDONB_01168	7.61e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HCIEDONB_01169	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCIEDONB_01170	1.52e-242	yqhT	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HCIEDONB_01171	2.25e-105	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HCIEDONB_01172	5.22e-112	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HCIEDONB_01173	3.08e-212	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HCIEDONB_01174	9.04e-18	yqhP	-	-	-	-	-	-	-
HCIEDONB_01175	1.53e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HCIEDONB_01176	1.21e-218	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HCIEDONB_01177	2.21e-225	paaX	-	-	K	ko:K02616	-	ko00000,ko03000	PaaX-like protein
HCIEDONB_01178	1.11e-281	pcaF	2.3.1.174, 2.3.1.223	-	I	ko:K02615	ko00360,ko01120,map00360,map01120	ko00000,ko00001,ko01000	Belongs to the thiolase family
HCIEDONB_01179	2.32e-196	hbd	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
HCIEDONB_01180	0.0	-	1.2.1.3, 1.2.1.8	-	C	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HCIEDONB_01181	7.88e-34	paaG	5.3.3.18	-	I	ko:K15866	ko00360,ko01120,map00360,map01120	ko00000,ko00001,ko01000	Enoyl-CoA hydratase
HCIEDONB_01182	2.69e-128	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HCIEDONB_01183	0.0	nrdA	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HCIEDONB_01184	2.74e-205	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HCIEDONB_01185	3.28e-87	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HCIEDONB_01186	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HCIEDONB_01187	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HCIEDONB_01188	2.03e-273	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HCIEDONB_01189	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HCIEDONB_01190	5.31e-200	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HCIEDONB_01191	3.69e-14	yqzE	-	-	S	-	-	-	YqzE-like protein
HCIEDONB_01192	2.04e-129	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HCIEDONB_01193	5.35e-81	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HCIEDONB_01194	1.27e-109	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	COG4940 Competence protein ComGF
HCIEDONB_01196	2.18e-101	comGD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	COG2165 Type II secretory pathway, pseudopilin PulG
HCIEDONB_01197	2.38e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HCIEDONB_01198	1.32e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HCIEDONB_01199	5.55e-267	comGA	-	-	NU	ko:K02243,ko:K02652	-	ko00000,ko00002,ko02035,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HCIEDONB_01200	1.29e-168	-	-	-	K	-	-	-	Helix-turn-helix domain
HCIEDONB_01201	1.31e-48	B4168_0554	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HCIEDONB_01202	2.01e-159	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HCIEDONB_01203	1.57e-30	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HCIEDONB_01204	5.87e-229	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HCIEDONB_01205	1.39e-40	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_01206	7.01e-267	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
HCIEDONB_01208	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HCIEDONB_01209	1.33e-70	yqzD	-	-	-	-	-	-	-
HCIEDONB_01210	0.0	pbpA	-	-	M	ko:K21465	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HCIEDONB_01211	5.85e-275	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HCIEDONB_01212	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HCIEDONB_01213	4.46e-72	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HCIEDONB_01214	1.11e-259	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HCIEDONB_01215	1.48e-146	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HCIEDONB_01216	1.33e-100	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HCIEDONB_01217	5.71e-181	zurM	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HCIEDONB_01218	5.46e-183	zurA	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HCIEDONB_01219	1.94e-27	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HCIEDONB_01220	3.61e-221	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HCIEDONB_01221	2.19e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCIEDONB_01222	7.05e-306	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCIEDONB_01224	1.66e-09	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HCIEDONB_01225	2.81e-231	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HCIEDONB_01226	2.86e-268	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCIEDONB_01227	1.43e-144	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HCIEDONB_01228	1.79e-84	cccA	-	-	C	ko:K13300	-	ko00000	Cytochrome C oxidase, cbb3-type, subunit III
HCIEDONB_01229	8.27e-112	-	-	-	-	-	-	-	-
HCIEDONB_01230	4.85e-258	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCIEDONB_01231	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCIEDONB_01232	3.84e-190	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCIEDONB_01233	4.15e-145	ccpN	-	-	K	-	-	-	CBS domain
HCIEDONB_01234	1.02e-184	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HCIEDONB_01235	8.43e-13	-	-	-	S	-	-	-	YqzL-like protein
HCIEDONB_01236	3.22e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCIEDONB_01237	6.81e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HCIEDONB_01238	8.37e-108	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCIEDONB_01239	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HCIEDONB_01240	4.98e-223	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HCIEDONB_01241	5.57e-290	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HCIEDONB_01242	1.56e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HCIEDONB_01243	1.07e-93	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HCIEDONB_01244	3.56e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HCIEDONB_01245	9.76e-64	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HCIEDONB_01246	9.67e-200	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HCIEDONB_01247	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HCIEDONB_01248	1.14e-174	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCIEDONB_01249	2.28e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HCIEDONB_01250	4.98e-272	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCIEDONB_01251	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HCIEDONB_01252	1.37e-126	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCIEDONB_01253	1.59e-243	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCIEDONB_01254	5.45e-280	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HCIEDONB_01255	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCIEDONB_01256	1.12e-286	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HCIEDONB_01257	4.85e-257	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HCIEDONB_01258	3.34e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HCIEDONB_01259	1.41e-241	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HCIEDONB_01260	1.18e-11	-	-	-	S	-	-	-	YqzM-like protein
HCIEDONB_01261	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HCIEDONB_01262	2.64e-146	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	COG2131 Deoxycytidylate deaminase
HCIEDONB_01263	2.72e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HCIEDONB_01264	1.62e-190	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCIEDONB_01265	6.43e-189	-	-	-	S	-	-	-	Methyltransferase domain
HCIEDONB_01266	1.02e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCIEDONB_01267	9.63e-130	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HCIEDONB_01268	2.28e-137	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCIEDONB_01269	2.57e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HCIEDONB_01270	3.2e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCIEDONB_01271	2.28e-272	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HCIEDONB_01272	1.11e-122	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HCIEDONB_01273	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HCIEDONB_01274	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HCIEDONB_01275	2.51e-261	ysfB	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HCIEDONB_01276	0.0	mco	-	-	Q	-	-	-	multicopper oxidases
HCIEDONB_01277	6.52e-98	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HCIEDONB_01278	4.63e-88	perX	-	-	S	-	-	-	DsrE/DsrF-like family
HCIEDONB_01279	1.14e-52	-	-	-	O	-	-	-	Glutaredoxin
HCIEDONB_01280	2.12e-72	-	-	-	P	-	-	-	Rhodanese Homology Domain
HCIEDONB_01281	0.0	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCIEDONB_01282	1.49e-31	-	-	-	S	ko:K08982	-	ko00000	Short C-terminal domain
HCIEDONB_01283	1.34e-297	mco	-	-	Q	-	-	-	multicopper oxidases
HCIEDONB_01284	1.32e-92	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HCIEDONB_01285	2.05e-42	-	-	-	S	ko:K08982	-	ko00000	Short C-terminal domain
HCIEDONB_01286	3.37e-126	stoA	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HCIEDONB_01288	2.06e-138	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HCIEDONB_01289	3.73e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HCIEDONB_01290	9.65e-79	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCIEDONB_01291	1.25e-86	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCIEDONB_01292	7.02e-151	-	-	-	S	-	-	-	VIT family
HCIEDONB_01293	5.45e-204	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HCIEDONB_01294	7.73e-22	sda	-	-	S	ko:K06371	-	ko00000	Sporulation inhibitor A
HCIEDONB_01295	3.27e-123	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCIEDONB_01296	3.64e-162	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEDONB_01298	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HCIEDONB_01299	3.96e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HCIEDONB_01301	2.49e-11	-	-	-	S	-	-	-	YrhC-like protein
HCIEDONB_01302	3.02e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCIEDONB_01303	2.82e-40	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HCIEDONB_01304	2.18e-99	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HCIEDONB_01305	7.42e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCIEDONB_01306	3.05e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HCIEDONB_01307	1.83e-148	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HCIEDONB_01308	6.42e-262	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCIEDONB_01309	9.07e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HCIEDONB_01310	7.49e-91	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCIEDONB_01311	2.76e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HCIEDONB_01312	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCIEDONB_01313	8.49e-245	yrrI	-	-	S	-	-	-	AI-2E family transporter
HCIEDONB_01315	3.5e-40	yrzR	-	-	-	-	-	-	-
HCIEDONB_01316	2.64e-88	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HCIEDONB_01317	9.11e-77	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
HCIEDONB_01318	2.49e-09	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
HCIEDONB_01319	1.52e-79	pdh	1.4.1.20	-	E	ko:K00270	ko00350,ko00360,ko00400,ko01100,ko01110,ko01130,map00350,map00360,map00400,map01100,map01110,map01130	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HCIEDONB_01321	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCIEDONB_01322	4.88e-162	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HCIEDONB_01323	7.16e-282	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCIEDONB_01324	1.22e-269	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HCIEDONB_01325	5.06e-94	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_01326	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_01327	7.17e-104	-	-	-	-	-	-	-	-
HCIEDONB_01328	1.28e-174	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Short-chain dehydrogenase reductase sdr
HCIEDONB_01329	3.06e-299	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HCIEDONB_01330	3.52e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HCIEDONB_01331	1e-222	ybaS	-	-	S	-	-	-	Na -dependent transporter
HCIEDONB_01333	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HCIEDONB_01334	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HCIEDONB_01336	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HCIEDONB_01337	0.0	yhcA5	-	-	EGP	-	-	-	the major facilitator superfamily
HCIEDONB_01338	3.83e-147	emrA	-	-	V	-	-	-	Barrel-sandwich domain of CusB or HlyD membrane-fusion
HCIEDONB_01339	5.15e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HCIEDONB_01340	2.76e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCIEDONB_01341	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCIEDONB_01342	1.2e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCIEDONB_01343	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HCIEDONB_01344	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HCIEDONB_01345	6.7e-72	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HCIEDONB_01346	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCIEDONB_01347	4.76e-137	yrbG	-	-	S	-	-	-	membrane
HCIEDONB_01348	3.79e-83	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HCIEDONB_01349	4.27e-66	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HCIEDONB_01350	1.07e-287	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCIEDONB_01351	1.42e-246	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCIEDONB_01352	4.52e-37	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HCIEDONB_01353	7.19e-235	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCIEDONB_01354	6.45e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCIEDONB_01355	2.12e-165	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HCIEDONB_01356	2.01e-245	-	-	-	M	-	-	-	choline kinase involved in LPS biosynthesis
HCIEDONB_01357	4.16e-222	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HCIEDONB_01358	8.93e-124	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HCIEDONB_01359	2.34e-203	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HCIEDONB_01360	4.36e-98	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HCIEDONB_01361	2.41e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCIEDONB_01362	3.03e-127	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HCIEDONB_01363	5.39e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HCIEDONB_01364	5.66e-70	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HCIEDONB_01365	2.58e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HCIEDONB_01366	0.0	rng	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	ribonuclease, Rne Rng family
HCIEDONB_01367	9.19e-209	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HCIEDONB_01368	5.41e-173	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HCIEDONB_01369	9e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HCIEDONB_01370	1.38e-156	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HCIEDONB_01371	2.23e-113	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HCIEDONB_01372	9.97e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HCIEDONB_01373	1.34e-233	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HCIEDONB_01374	4.65e-158	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HCIEDONB_01375	2.44e-219	spoIIB	-	-	-	ko:K06380	-	ko00000	-
HCIEDONB_01376	8.38e-183	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HCIEDONB_01377	1.77e-145	-	-	-	-	ko:K02664	-	ko00000,ko02035,ko02044	-
HCIEDONB_01378	3.48e-134	-	-	-	NU	ko:K02663	-	ko00000,ko02035,ko02044	PFAM Fimbrial assembly family protein
HCIEDONB_01379	4.37e-241	-	-	-	NU	ko:K02662,ko:K02663	-	ko00000,ko02035,ko02044	COG4972 Tfp pilus assembly protein, ATPase PilM
HCIEDONB_01380	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_01381	8.08e-28	-	-	-	NU	ko:K02650	ko02020,map02020	ko00000,ko00001,ko02035,ko02044	cell adhesion
HCIEDONB_01382	1.45e-262	pilC	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	type II secretion system
HCIEDONB_01383	4.58e-247	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	twitching motility protein
HCIEDONB_01384	0.0	pilB	-	-	NU	ko:K02243,ko:K02652	-	ko00000,ko00002,ko02035,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HCIEDONB_01385	3.08e-269	-	-	-	V	-	-	-	G5
HCIEDONB_01386	8.26e-164	-	-	-	S	-	-	-	PRC-barrel domain
HCIEDONB_01387	6.01e-236	-	-	-	-	-	-	-	-
HCIEDONB_01388	1.85e-307	-	-	-	NU	-	-	-	Pilus assembly protein PilX
HCIEDONB_01389	4.02e-110	-	-	-	-	-	-	-	-
HCIEDONB_01390	9.73e-06	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HCIEDONB_01391	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HCIEDONB_01392	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCIEDONB_01393	3.74e-36	-	-	-	-	-	-	-	-
HCIEDONB_01394	1.21e-287	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HCIEDONB_01395	4.72e-304	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HCIEDONB_01396	9.69e-317	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HCIEDONB_01397	6.18e-237	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HCIEDONB_01398	9.06e-187	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HCIEDONB_01399	1.26e-217	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HCIEDONB_01400	8.69e-191	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HCIEDONB_01401	1.09e-308	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HCIEDONB_01402	3.11e-116	ysxD	-	-	-	-	-	-	-
HCIEDONB_01403	8.22e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HCIEDONB_01404	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HCIEDONB_01405	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HCIEDONB_01406	1.2e-299	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCIEDONB_01407	6.4e-282	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCIEDONB_01408	3.56e-234	-	-	-	S	-	-	-	chaperone-mediated protein folding
HCIEDONB_01409	1.08e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HCIEDONB_01410	1.26e-61	-	-	-	-	-	-	-	-
HCIEDONB_01415	4.92e-120	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HCIEDONB_01416	3.72e-138	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCIEDONB_01417	1.59e-245	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HCIEDONB_01418	4.29e-32	yraE	-	-	-	ko:K06440	-	ko00000	-
HCIEDONB_01419	1.46e-61	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HCIEDONB_01420	1.76e-281	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HCIEDONB_01421	5.35e-81	yraF	-	-	M	-	-	-	Spore coat protein
HCIEDONB_01422	2.16e-43	yraG	-	-	S	ko:K06440	-	ko00000	Spore Coat Protein
HCIEDONB_01423	7.48e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HCIEDONB_01424	9.88e-105	ysmB	-	-	K	-	-	-	transcriptional
HCIEDONB_01425	2.51e-120	-	-	-	S	-	-	-	GDYXXLXY protein
HCIEDONB_01426	2.11e-249	-	-	-	S	-	-	-	Predicted membrane protein (DUF2157)
HCIEDONB_01428	3.8e-43	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_01429	1.33e-114	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HCIEDONB_01430	8.45e-193	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HCIEDONB_01431	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HCIEDONB_01432	7.21e-136	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HCIEDONB_01433	4.17e-107	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HCIEDONB_01434	1.86e-285	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HCIEDONB_01435	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCIEDONB_01436	9.61e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HCIEDONB_01437	1.66e-221	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HCIEDONB_01438	3.94e-174	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HCIEDONB_01439	5e-177	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HCIEDONB_01440	5.75e-135	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_01441	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCIEDONB_01442	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCIEDONB_01443	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HCIEDONB_01444	2.58e-115	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HCIEDONB_01445	3.12e-61	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HCIEDONB_01446	7.89e-217	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCIEDONB_01447	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCIEDONB_01448	1.56e-256	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCIEDONB_01449	1.1e-177	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCIEDONB_01450	2.36e-42	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HCIEDONB_01451	8.04e-101	-	-	-	-	-	-	-	-
HCIEDONB_01452	0.0	-	-	-	L	-	-	-	Transposase
HCIEDONB_01453	3.97e-295	-	-	-	L	ko:K07486	-	ko00000	COG3547 Transposase and inactivated derivatives
HCIEDONB_01454	4.39e-191	-	-	-	S	-	-	-	Domain of unknown function (DUF4405)
HCIEDONB_01455	8.95e-65	-	-	-	-	-	-	-	-
HCIEDONB_01456	1.32e-74	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HCIEDONB_01457	1.22e-155	M1-1017	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HCIEDONB_01458	1.43e-73	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_01459	1.54e-15	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HCIEDONB_01460	2.72e-163	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HCIEDONB_01461	6.34e-227	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCIEDONB_01462	9.73e-132	-	-	-	S	ko:K19784	-	ko00000	NAD(P)H-dependent FMN reductase
HCIEDONB_01463	1.38e-211	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HCIEDONB_01464	1.62e-229	-	-	-	C	-	-	-	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HCIEDONB_01465	3.94e-123	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCIEDONB_01466	0.0	-	-	-	M	-	-	-	O-Antigen ligase
HCIEDONB_01467	1.36e-101	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HCIEDONB_01469	3.16e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCIEDONB_01470	4.3e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HCIEDONB_01471	8.37e-145	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCIEDONB_01472	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_01473	1.64e-284	-	-	-	G	-	-	-	Transmembrane secretion effector
HCIEDONB_01474	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCIEDONB_01475	3.3e-197	ytxC	-	-	S	-	-	-	YtxC-like family
HCIEDONB_01476	1.5e-227	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HCIEDONB_01477	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HCIEDONB_01478	4.02e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCIEDONB_01479	9.61e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCIEDONB_01480	1.2e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCIEDONB_01481	5.02e-141	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HCIEDONB_01482	2e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCIEDONB_01483	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCIEDONB_01484	2.75e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HCIEDONB_01485	2.57e-311	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HCIEDONB_01486	1.08e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HCIEDONB_01487	5.22e-97	-	-	-	S	-	-	-	Membrane
HCIEDONB_01488	2.16e-231	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HCIEDONB_01489	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HCIEDONB_01490	1.38e-226	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCIEDONB_01491	8.01e-228	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HCIEDONB_01492	2.01e-209	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCIEDONB_01493	3.79e-290	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HCIEDONB_01494	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HCIEDONB_01495	1.23e-69	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HCIEDONB_01496	7.28e-117	ytrI	-	-	-	-	-	-	-
HCIEDONB_01497	5.84e-224	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HCIEDONB_01498	6.6e-59	ytpI	-	-	S	-	-	-	YtpI-like protein
HCIEDONB_01499	2.88e-306	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HCIEDONB_01500	1.57e-165	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HCIEDONB_01501	4.51e-261	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HCIEDONB_01502	8.71e-258	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HCIEDONB_01503	4.68e-104	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCIEDONB_01504	6.19e-201	-	-	-	S	-	-	-	EcsC protein family
HCIEDONB_01505	2.07e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCIEDONB_01506	2.05e-230	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HCIEDONB_01507	7.88e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCIEDONB_01508	1.39e-96	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HCIEDONB_01509	5.22e-153	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HCIEDONB_01510	6.64e-116	yteJ	-	-	S	-	-	-	RDD family
HCIEDONB_01511	1.7e-236	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HCIEDONB_01512	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HCIEDONB_01513	7.27e-38	B4168_3115	-	-	S	ko:K06419	-	ko00000	spore protein
HCIEDONB_01514	1.25e-284	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCIEDONB_01515	2.38e-273	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HCIEDONB_01516	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCIEDONB_01517	1.07e-151	yttP	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_01518	2.3e-111	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HCIEDONB_01519	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HCIEDONB_01520	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCIEDONB_01521	3.84e-186	-	-	-	-	-	-	-	-
HCIEDONB_01522	5.58e-94	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCIEDONB_01523	4.01e-236	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HCIEDONB_01524	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HCIEDONB_01525	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
HCIEDONB_01526	1.4e-301	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCIEDONB_01527	3.86e-196	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HCIEDONB_01528	9.99e-269	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_01529	7.73e-22	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HCIEDONB_01530	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HCIEDONB_01531	4.84e-114	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HCIEDONB_01532	4.24e-248	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HCIEDONB_01533	1.01e-111	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HCIEDONB_01534	1.45e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HCIEDONB_01535	1.16e-102	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HCIEDONB_01536	1.55e-114	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HCIEDONB_01537	2.53e-303	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HCIEDONB_01538	4.82e-155	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HCIEDONB_01539	2.75e-111	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HCIEDONB_01540	6.26e-259	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HCIEDONB_01541	5.26e-166	-	3.6.3.29	-	P	ko:K02017	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCIEDONB_01542	8.94e-162	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HCIEDONB_01543	2.29e-157	-	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Molybdenum ABC transporter
HCIEDONB_01544	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HCIEDONB_01545	1.16e-154	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HCIEDONB_01546	6.93e-154	acuB	-	-	S	ko:K04767	-	ko00000	Acetoin utilization protein AcuB
HCIEDONB_01547	9.26e-296	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HCIEDONB_01548	2.93e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HCIEDONB_01549	3.79e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HCIEDONB_01550	1.51e-52	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HCIEDONB_01551	2.32e-85	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCIEDONB_01552	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HCIEDONB_01553	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HCIEDONB_01554	9.16e-128	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCIEDONB_01555	7.55e-142	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCIEDONB_01556	3.03e-186	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HCIEDONB_01557	9.98e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
HCIEDONB_01558	2.86e-267	rsbU	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
HCIEDONB_01559	2.15e-198	-	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	chemotaxis
HCIEDONB_01560	0.0	-	2.7.13.3	-	T	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	Histidine kinase
HCIEDONB_01561	6.29e-206	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HCIEDONB_01562	1.73e-33	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HCIEDONB_01564	1.13e-93	-	-	-	-	-	-	-	-
HCIEDONB_01565	1.07e-119	yjjX	-	-	F	-	-	-	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HCIEDONB_01566	3.18e-262	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HCIEDONB_01567	2.11e-69	ytzB	-	-	S	-	-	-	small secreted protein
HCIEDONB_01568	1.06e-216	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HCIEDONB_01569	9.87e-175	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCIEDONB_01570	2.45e-79	ytzH	-	-	S	-	-	-	YtzH-like protein
HCIEDONB_01571	2.25e-201	ytmP	-	-	M	-	-	-	Phosphotransferase
HCIEDONB_01572	5.12e-199	ytlQ	-	-	-	-	-	-	-
HCIEDONB_01573	4.8e-139	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HCIEDONB_01575	4.89e-204	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HCIEDONB_01576	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HCIEDONB_01577	9e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HCIEDONB_01578	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCIEDONB_01579	1.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HCIEDONB_01580	7.61e-13	-	-	-	-	-	-	-	-
HCIEDONB_01582	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HCIEDONB_01583	2.51e-237	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HCIEDONB_01584	9.55e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HCIEDONB_01585	1.37e-134	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HCIEDONB_01587	2.36e-272	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HCIEDONB_01588	5.29e-198	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HCIEDONB_01589	1.29e-107	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HCIEDONB_01590	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HCIEDONB_01591	2.15e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCIEDONB_01592	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HCIEDONB_01593	1.28e-89	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
HCIEDONB_01594	2.33e-265	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HCIEDONB_01595	1.02e-131	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
HCIEDONB_01596	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HCIEDONB_01597	3.29e-235	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HCIEDONB_01598	1.18e-179	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCIEDONB_01599	2.93e-170	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCIEDONB_01600	9.28e-109	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HCIEDONB_01601	2.31e-52	-	-	-	-	-	-	-	-
HCIEDONB_01602	6.23e-102	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HCIEDONB_01603	1.27e-54	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HCIEDONB_01604	4.9e-208	adcA	-	-	P	ko:K09815,ko:K09818	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HCIEDONB_01605	2.35e-32	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HCIEDONB_01606	1.86e-266	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HCIEDONB_01607	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HCIEDONB_01608	3.73e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HCIEDONB_01609	1.4e-197	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HCIEDONB_01610	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HCIEDONB_01611	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HCIEDONB_01612	6.2e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HCIEDONB_01633	1.62e-57	-	-	-	-	-	-	-	-
HCIEDONB_01634	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HCIEDONB_01635	2.82e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HCIEDONB_01637	2.03e-296	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
HCIEDONB_01638	4.22e-36	-	-	-	-	-	-	-	-
HCIEDONB_01639	1.01e-198	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HCIEDONB_01640	1.13e-150	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HCIEDONB_01641	1.22e-217	-	-	-	S	-	-	-	Protein of unknown function (DUF1646)
HCIEDONB_01642	2.02e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCIEDONB_01643	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HCIEDONB_01644	1.19e-41	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
HCIEDONB_01645	1.64e-74	csoR_2	-	-	S	ko:K21600	-	ko00000,ko03000	protein conserved in bacteria
HCIEDONB_01646	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
HCIEDONB_01648	3.2e-91	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HCIEDONB_01649	1.46e-97	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HCIEDONB_01650	5.33e-287	-	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HCIEDONB_01651	5.91e-38	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HCIEDONB_01652	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCIEDONB_01654	4.34e-39	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
HCIEDONB_01655	5.55e-42	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
HCIEDONB_01657	1.69e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2933)
HCIEDONB_01659	0.0	-	-	-	T	-	-	-	Histidine kinase
HCIEDONB_01660	2.51e-165	-	-	-	KT	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEDONB_01661	4.45e-128	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HCIEDONB_01662	2.88e-131	ypiA	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HCIEDONB_01664	4.44e-223	nodB1	-	-	G	-	-	-	deacetylase
HCIEDONB_01667	1.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HCIEDONB_01669	4.15e-313	-	-	-	P	-	-	-	Voltage gated chloride channel
HCIEDONB_01670	5.53e-65	-	-	-	P	-	-	-	Rhodanese domain protein
HCIEDONB_01671	6.22e-52	csoR	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_01672	2.22e-187	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HCIEDONB_01673	1.45e-92	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HCIEDONB_01674	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HCIEDONB_01675	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HCIEDONB_01677	3.26e-292	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HCIEDONB_01678	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HCIEDONB_01679	2.31e-165	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HCIEDONB_01680	4.12e-314	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
HCIEDONB_01682	1.03e-128	msmG	-	-	G	ko:K02026,ko:K10122	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCIEDONB_01683	5.59e-135	-	-	-	P	ko:K10121	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HCIEDONB_01684	2.82e-160	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Arabinose-binding protein
HCIEDONB_01685	6.07e-188	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HCIEDONB_01686	4.35e-165	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HCIEDONB_01687	5.85e-187	lacY	-	-	G	ko:K02532	-	ko00000,ko02000	Permeases of the major facilitator superfamily
HCIEDONB_01688	1.77e-307	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HCIEDONB_01689	5.19e-174	-	-	-	L	-	-	-	PFAM Transposase, Mutator
HCIEDONB_01690	1.56e-60	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HCIEDONB_01691	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HCIEDONB_01692	9.81e-165	-	-	-	I	-	-	-	Acyl-transferase
HCIEDONB_01693	7.17e-258	-	-	-	M	-	-	-	Glycosyl transferase family 2
HCIEDONB_01694	3.96e-180	fabG9	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HCIEDONB_01695	1.75e-100	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HCIEDONB_01696	3.24e-270	solA	1.5.3.1	-	E	ko:K00301,ko:K02846	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HCIEDONB_01697	4.31e-278	-	1.5.3.1	-	E	ko:K00303	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HCIEDONB_01698	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCIEDONB_01699	9.54e-218	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	ornithine cyclodeaminase
HCIEDONB_01702	9.28e-234	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HCIEDONB_01703	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HCIEDONB_01704	1.11e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HCIEDONB_01705	1.9e-113	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HCIEDONB_01706	9.05e-85	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HCIEDONB_01707	4.29e-40	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCIEDONB_01708	7.94e-249	yqjM1	-	-	C	-	-	-	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HCIEDONB_01709	1.53e-210	-	-	-	S	-	-	-	reductase
HCIEDONB_01710	2.52e-202	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
HCIEDONB_01711	3.32e-303	-	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_01712	3.54e-06	-	-	-	-	-	-	-	-
HCIEDONB_01713	2.75e-143	ppiA	5.2.1.8	-	O	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCIEDONB_01714	1.29e-88	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HCIEDONB_01715	4.49e-262	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HCIEDONB_01716	7.74e-86	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HCIEDONB_01717	2.69e-74	yuzC	-	-	-	-	-	-	-
HCIEDONB_01719	3.89e-246	gerKB	-	-	E	ko:K06296	-	ko00000,ko02000	Spore germination protein
HCIEDONB_01720	1.16e-285	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HCIEDONB_01721	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HCIEDONB_01723	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HCIEDONB_01724	7.5e-139	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_01725	1.04e-61	yuiB	-	-	S	-	-	-	Putative membrane protein
HCIEDONB_01726	1.21e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HCIEDONB_01727	1.4e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HCIEDONB_01728	1.18e-71	-	-	-	S	-	-	-	response to antibiotic
HCIEDONB_01729	4.36e-100	-	-	-	S	-	-	-	response to antibiotic
HCIEDONB_01730	1.17e-90	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HCIEDONB_01731	4.8e-83	yutM	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HCIEDONB_01732	3.46e-80	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_01733	6.83e-50	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HCIEDONB_01734	4.28e-254	yutH	-	-	S	-	-	-	Spore coat protein
HCIEDONB_01735	5.12e-112	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HCIEDONB_01736	2.79e-177	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCIEDONB_01737	1.26e-95	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HCIEDONB_01738	4.18e-64	yutD	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_01739	3.37e-220	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HCIEDONB_01740	8.26e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HCIEDONB_01741	4.78e-162	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HCIEDONB_01742	3.71e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
HCIEDONB_01743	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HCIEDONB_01744	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HCIEDONB_01745	2.18e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HCIEDONB_01746	1.58e-302	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCIEDONB_01747	1.01e-309	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HCIEDONB_01748	2.3e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HCIEDONB_01750	6.58e-68	yusE	-	-	CO	-	-	-	Thioredoxin
HCIEDONB_01751	1.7e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HCIEDONB_01752	8.99e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HCIEDONB_01753	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HCIEDONB_01754	5.89e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HCIEDONB_01755	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HCIEDONB_01756	3.69e-21	-	-	-	S	-	-	-	YuzL-like protein
HCIEDONB_01757	8.24e-56	-	-	-	-	-	-	-	-
HCIEDONB_01758	2.73e-73	yusN	-	-	M	-	-	-	Coat F domain
HCIEDONB_01759	7.48e-261	-	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HCIEDONB_01760	1.4e-73	ydbP	-	-	CO	-	-	-	Thioredoxin
HCIEDONB_01761	0.0	cls2	-	-	I	-	-	-	PLD-like domain
HCIEDONB_01762	2.88e-10	-	-	-	-	-	-	-	-
HCIEDONB_01763	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HCIEDONB_01765	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
HCIEDONB_01766	7.61e-247	M1-600	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HCIEDONB_01767	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HCIEDONB_01768	4.97e-138	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HCIEDONB_01769	3.17e-184	-	-	-	G	-	-	-	Polysaccharide deacetylase
HCIEDONB_01770	1.96e-312	ugtP5	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Monogalactosyldiacylglycerol (MGDG) synthase
HCIEDONB_01771	4.34e-184	-	-	-	-	-	-	-	-
HCIEDONB_01772	9.54e-113	-	-	-	S	-	-	-	Putative zinc-finger
HCIEDONB_01773	1.34e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HCIEDONB_01774	1.93e-286	ykoN	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HCIEDONB_01775	0.0	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HCIEDONB_01776	9.15e-214	-	-	-	NU	ko:K02650	ko02020,map02020	ko00000,ko00001,ko02035,ko02044	cell adhesion
HCIEDONB_01777	1.1e-95	-	-	-	NU	ko:K02650	ko02020,map02020	ko00000,ko00001,ko02035,ko02044	cell adhesion
HCIEDONB_01778	2.26e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HCIEDONB_01779	1.82e-228	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HCIEDONB_01780	6.51e-214	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HCIEDONB_01781	3.54e-182	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEDONB_01782	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HCIEDONB_01783	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HCIEDONB_01784	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HCIEDONB_01785	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HCIEDONB_01786	4.4e-246	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HCIEDONB_01787	5.43e-156	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HCIEDONB_01788	9.33e-177	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
HCIEDONB_01789	2.08e-10	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
HCIEDONB_01790	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_01791	1.27e-26	-	-	-	-	-	-	-	-
HCIEDONB_01793	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HCIEDONB_01794	4.99e-72	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HCIEDONB_01795	9.66e-253	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_01796	1.63e-68	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_01797	1.18e-07	-	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HCIEDONB_01798	5.88e-277	-	-	-	O	-	-	-	Peptidase S53
HCIEDONB_01799	3.94e-49	XK26_06125	-	-	S	-	-	-	Transcriptional Coactivator p15 (PC4)
HCIEDONB_01801	7.44e-38	-	-	-	D	-	-	-	nuclear chromosome segregation
HCIEDONB_01802	1.15e-49	-	-	-	-	-	-	-	-
HCIEDONB_01803	1.09e-46	-	-	-	-	-	-	-	-
HCIEDONB_01804	2.15e-126	-	-	-	-	-	-	-	-
HCIEDONB_01805	5.69e-207	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_01807	9.83e-106	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HCIEDONB_01808	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCIEDONB_01809	2.93e-181	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HCIEDONB_01810	1.07e-39	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HCIEDONB_01812	3.5e-308	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCIEDONB_01813	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HCIEDONB_01814	9.52e-164	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCIEDONB_01815	2.06e-279	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HCIEDONB_01816	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCIEDONB_01817	1.2e-238	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HCIEDONB_01818	6.4e-54	XAC3035	-	-	O	ko:K06191	-	ko00000	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HCIEDONB_01819	1.44e-309	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HCIEDONB_01820	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_01822	1.09e-05	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HCIEDONB_01823	2.74e-112	-	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HCIEDONB_01825	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HCIEDONB_01826	1.91e-42	-	-	-	-	-	-	-	-
HCIEDONB_01828	1.57e-102	-	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HCIEDONB_01829	1.6e-172	-	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HCIEDONB_01831	1.66e-24	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_01832	1.82e-21	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_01833	1.64e-25	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_01834	2.73e-209	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_01835	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HCIEDONB_01836	2.54e-112	nhaX	-	-	T	-	-	-	Universal stress protein
HCIEDONB_01838	1.26e-242	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCIEDONB_01839	1.01e-228	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HCIEDONB_01840	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HCIEDONB_01841	1.78e-241	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCIEDONB_01842	7.38e-225	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEDONB_01843	4.48e-206	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEDONB_01844	2.4e-168	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HCIEDONB_01845	8.77e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HCIEDONB_01846	2.04e-60	yhdB	-	-	S	-	-	-	YhdB-like protein
HCIEDONB_01848	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HCIEDONB_01849	4.35e-238	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HCIEDONB_01850	7.2e-174	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HCIEDONB_01851	2.13e-101	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HCIEDONB_01852	3.01e-112	bdbA	-	-	CO	-	-	-	Thioredoxin
HCIEDONB_01853	2.35e-117	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HCIEDONB_01854	5.31e-149	ykaA	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
HCIEDONB_01855	4.46e-229	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HCIEDONB_01856	1.74e-135	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HCIEDONB_01858	3.3e-282	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HCIEDONB_01859	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HCIEDONB_01861	1.89e-114	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCIEDONB_01862	2.47e-220	yhbB	-	-	S	-	-	-	Putative amidase domain
HCIEDONB_01863	9.08e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HCIEDONB_01864	6.11e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HCIEDONB_01865	2.95e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HCIEDONB_01866	1.29e-110	yhjR	-	-	S	-	-	-	Rubrerythrin
HCIEDONB_01867	6.5e-212	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HCIEDONB_01868	2.8e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HCIEDONB_01869	8.56e-151	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HCIEDONB_01870	2.38e-169	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HCIEDONB_01871	7.14e-192	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
HCIEDONB_01873	5.98e-209	-	-	-	L	ko:K07494	-	ko00000	DDE superfamily endonuclease
HCIEDONB_01875	4.81e-274	-	1.1.1.1	-	C	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HCIEDONB_01876	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase
HCIEDONB_01877	1.15e-185	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCIEDONB_01878	2.04e-129	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
HCIEDONB_01879	3.03e-118	-	-	-	-	-	-	-	-
HCIEDONB_01880	1.36e-220	bcrB	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HCIEDONB_01881	2.75e-213	bcrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCIEDONB_01882	7.71e-186	-	-	-	E	-	-	-	G-D-S-L family
HCIEDONB_01883	3.08e-43	-	-	-	-	-	-	-	-
HCIEDONB_01885	2.63e-223	-	-	-	S	-	-	-	High confidence in function and specificity
HCIEDONB_01886	4.85e-167	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEDONB_01887	0.0	ykoH	-	-	T	-	-	-	Histidine kinase
HCIEDONB_01888	3.04e-141	-	-	-	-	-	-	-	-
HCIEDONB_01889	6.23e-55	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HCIEDONB_01891	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_01892	0.0	-	-	-	L	-	-	-	Mu transposase, C-terminal
HCIEDONB_01893	2.94e-194	-	-	-	U	-	-	-	AAA domain
HCIEDONB_01894	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_01897	8.14e-105	-	-	-	K	-	-	-	AraC-like ligand binding domain
HCIEDONB_01898	4.97e-165	pbg	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HCIEDONB_01899	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_01901	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_01902	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
HCIEDONB_01903	4.47e-118	-	-	-	L	-	-	-	Transposase
HCIEDONB_01904	4.63e-236	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_01905	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_01906	4.23e-190	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HCIEDONB_01907	2.01e-265	adhC	1.1.1.1, 1.1.1.90	-	C	ko:K00001,ko:K00055	ko00010,ko00071,ko00350,ko00360,ko00622,ko00623,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00360,map00622,map00623,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HCIEDONB_01909	4.21e-242	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCIEDONB_01910	2.45e-39	yetF3	-	-	K	-	-	-	membrane
HCIEDONB_01911	4.12e-31	yetF3	-	-	K	-	-	-	membrane
HCIEDONB_01927	1.39e-58	-	-	-	-	-	-	-	-
HCIEDONB_01930	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HCIEDONB_01931	1.07e-208	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HCIEDONB_01932	3.29e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
HCIEDONB_01933	3.99e-179	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HCIEDONB_01934	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HCIEDONB_01935	3.33e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HCIEDONB_01936	7.99e-108	arcR	-	-	K	ko:K21828	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_01937	2.25e-139	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HCIEDONB_01938	8.36e-236	-	-	-	E	ko:K03758	-	ko00000,ko02000	amino acid
HCIEDONB_01939	5.71e-184	arcB	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCIEDONB_01940	1.17e-221	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine deiminase
HCIEDONB_01941	2.85e-107	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HCIEDONB_01942	2.29e-130	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HCIEDONB_01943	2.97e-86	-	-	-	P	ko:K08713	-	ko00000,ko02000	Ion transport
HCIEDONB_01944	6.38e-315	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HCIEDONB_01945	4.73e-241	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HCIEDONB_01946	5.87e-182	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCIEDONB_01947	1.5e-185	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HCIEDONB_01948	4.53e-137	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCIEDONB_01949	7.1e-292	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HCIEDONB_01950	1.63e-71	-	-	-	-	-	-	-	-
HCIEDONB_01951	1.41e-53	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HCIEDONB_01952	5.71e-241	ygaE	-	-	S	-	-	-	Membrane
HCIEDONB_01953	2.41e-200	yleF	-	-	K	-	-	-	transcriptional
HCIEDONB_01954	0.0	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCIEDONB_01955	4.28e-197	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCIEDONB_01956	1.16e-265	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HCIEDONB_01957	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HCIEDONB_01958	5.7e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HCIEDONB_01959	1.49e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
HCIEDONB_01960	2.95e-23	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HCIEDONB_01961	1.13e-169	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEDONB_01962	1.59e-211	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_01963	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HCIEDONB_01965	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HCIEDONB_01966	6.32e-42	-	-	-	-	-	-	-	-
HCIEDONB_01968	2.22e-183	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
HCIEDONB_01969	3.12e-61	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
HCIEDONB_01970	2.85e-252	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HCIEDONB_01971	5.26e-234	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HCIEDONB_01972	3.78e-29	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
HCIEDONB_01973	8.2e-68	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HCIEDONB_01974	2.6e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HCIEDONB_01975	2.54e-09	-	-	-	S	-	-	-	YfhE-like protein
HCIEDONB_01976	1.2e-33	yfhD	-	-	S	-	-	-	YfhD-like protein
HCIEDONB_01977	3.41e-187	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCIEDONB_01978	1.6e-291	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCIEDONB_01979	0.0	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HCIEDONB_01980	2.2e-229	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCIEDONB_01981	8.84e-140	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase
HCIEDONB_01982	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCIEDONB_01983	2.23e-262	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HCIEDONB_01984	7.95e-107	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCIEDONB_01985	8.15e-242	bacG	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCIEDONB_01987	5.35e-12	-	-	-	-	-	-	-	-
HCIEDONB_01988	1.29e-113	-	-	-	S	-	-	-	Stage II sporulation protein M
HCIEDONB_01989	6.86e-163	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HCIEDONB_01991	1.48e-62	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
HCIEDONB_01993	0.0	-	-	-	-	-	-	-	-
HCIEDONB_01994	4.79e-35	-	-	-	-	-	-	-	-
HCIEDONB_01996	2.3e-80	-	-	-	-	-	-	-	-
HCIEDONB_01997	7.15e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HCIEDONB_01999	3.4e-146	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCIEDONB_02000	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCIEDONB_02002	3.47e-209	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
HCIEDONB_02003	2.39e-165	-	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HCIEDONB_02004	9.93e-266	-	-	-	Q	-	-	-	Male sterility protein
HCIEDONB_02005	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCIEDONB_02007	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HCIEDONB_02008	1.15e-234	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIEDONB_02009	1.06e-277	sgaA	-	-	E	-	-	-	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HCIEDONB_02010	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIEDONB_02011	1.1e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HCIEDONB_02012	5.41e-275	-	-	-	S	-	-	-	HAD-hyrolase-like
HCIEDONB_02013	1.34e-240	tdcB_1	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HCIEDONB_02014	1.04e-141	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCIEDONB_02015	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCIEDONB_02016	9.78e-257	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HCIEDONB_02017	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HCIEDONB_02018	6.29e-250	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HCIEDONB_02019	1.9e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HCIEDONB_02020	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HCIEDONB_02021	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HCIEDONB_02022	8.71e-313	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HCIEDONB_02023	2.47e-191	rsbRD	-	-	T	ko:K17763	-	ko00000,ko03021	STAS domain
HCIEDONB_02024	8.6e-312	-	-	-	-	-	-	-	-
HCIEDONB_02025	2.03e-07	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HCIEDONB_02026	9.99e-269	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_02027	7.73e-22	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HCIEDONB_02028	1.21e-70	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HCIEDONB_02029	1.18e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HCIEDONB_02030	3.78e-273	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HCIEDONB_02031	8.1e-281	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major facilitator superfamily
HCIEDONB_02032	2.21e-176	-	-	-	T	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain
HCIEDONB_02033	0.0	ypdA3	2.7.13.3	-	T	ko:K02478,ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HCIEDONB_02034	1.08e-248	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HCIEDONB_02037	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HCIEDONB_02038	4.07e-138	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_02039	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HCIEDONB_02040	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2397)
HCIEDONB_02041	9.64e-295	-	-	-	S	-	-	-	Protein of unknown function (DUF2398)
HCIEDONB_02042	0.0	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
HCIEDONB_02043	0.0	-	-	-	S	-	-	-	Protein of unknown function N-terminus (DUF3323)
HCIEDONB_02044	2.66e-112	-	-	-	-	-	-	-	-
HCIEDONB_02046	9.34e-271	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HCIEDONB_02047	1.51e-200	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
HCIEDONB_02048	8.52e-41	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_02049	9.63e-100	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HCIEDONB_02050	4.88e-79	-	-	-	-	ko:K06327	-	ko00000	-
HCIEDONB_02051	7.26e-303	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCIEDONB_02052	3.76e-97	-	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HCIEDONB_02053	0.0	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
HCIEDONB_02054	1.79e-113	-	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HCIEDONB_02055	2.75e-116	-	-	-	S	-	-	-	AAA domain
HCIEDONB_02056	3.02e-44	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
HCIEDONB_02057	6.99e-136	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
HCIEDONB_02058	3.34e-267	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_02059	2.69e-22	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HCIEDONB_02060	1.37e-84	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
HCIEDONB_02061	1.19e-35	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
HCIEDONB_02062	4.22e-245	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCIEDONB_02063	4.5e-66	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCIEDONB_02064	7.39e-184	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCIEDONB_02065	4.44e-201	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HCIEDONB_02066	3.32e-240	fabH5	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
HCIEDONB_02067	8.01e-77	-	-	-	-	-	-	-	-
HCIEDONB_02069	0.0	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HCIEDONB_02071	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HCIEDONB_02072	1.77e-130	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HCIEDONB_02073	2.59e-89	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCIEDONB_02074	0.0	-	3.6.3.16	-	D	ko:K01551	-	ko00000,ko01000,ko02000	Anion-transporting ATPase
HCIEDONB_02075	4.68e-75	-	-	-	S	-	-	-	Arsenical resistance operon trans-acting repressor ArsD
HCIEDONB_02076	2e-112	-	-	-	Q	-	-	-	methyltransferase
HCIEDONB_02077	4.4e-231	-	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
HCIEDONB_02078	2.3e-114	padR	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
HCIEDONB_02079	9.13e-61	-	-	-	K	ko:K03892	-	ko00000,ko03000	Helix-turn-helix domain
HCIEDONB_02080	1.03e-98	-	-	-	-	-	-	-	-
HCIEDONB_02081	5.55e-185	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
HCIEDONB_02082	6.34e-191	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HCIEDONB_02083	5.38e-309	-	-	-	L	ko:K07486	-	ko00000	COG3547 Transposase and inactivated derivatives
HCIEDONB_02084	1.34e-241	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Major facilitator superfamily
HCIEDONB_02085	2.82e-186	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
HCIEDONB_02086	8.73e-122	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HCIEDONB_02087	5.4e-204	-	-	-	S	-	-	-	Pfam:DUF303
HCIEDONB_02088	3.34e-144	-	-	-	L	-	-	-	PFAM transposase IS4 family protein
HCIEDONB_02089	4.96e-251	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
HCIEDONB_02090	1.43e-251	-	-	-	-	-	-	-	-
HCIEDONB_02091	4.04e-25	-	-	-	S	-	-	-	permease
HCIEDONB_02092	1.93e-197	-	-	-	S	-	-	-	permease
HCIEDONB_02093	5.59e-41	-	-	-	-	-	-	-	-
HCIEDONB_02094	2.45e-199	-	-	-	L	-	-	-	resolvase
HCIEDONB_02095	7.26e-260	-	-	-	L	ko:K07486	-	ko00000	Transposase IS116/IS110/IS902 family
HCIEDONB_02096	1.69e-277	-	-	-	S	-	-	-	permease
HCIEDONB_02097	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_02098	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02099	2.52e-137	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
HCIEDONB_02100	0.0	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	PFAM DNA methylase
HCIEDONB_02101	0.0	-	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HCIEDONB_02102	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCIEDONB_02103	3.76e-212	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HCIEDONB_02104	2.32e-189	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HCIEDONB_02105	1.28e-37	yfjT	-	-	-	-	-	-	-
HCIEDONB_02106	3.16e-188	yfkD	-	-	S	-	-	-	YfkD-like protein
HCIEDONB_02107	1.17e-230	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HCIEDONB_02108	2.06e-279	yfkF	-	-	EGP	-	-	-	Major facilitator superfamily
HCIEDONB_02109	4.82e-191	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HCIEDONB_02110	6.01e-45	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HCIEDONB_02111	3.85e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HCIEDONB_02112	3.88e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HCIEDONB_02113	6.56e-186	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HCIEDONB_02114	5.98e-174	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HCIEDONB_02115	3.26e-76	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HCIEDONB_02117	4.69e-79	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HCIEDONB_02118	1.96e-291	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HCIEDONB_02119	1.11e-188	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HCIEDONB_02120	1.63e-110	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HCIEDONB_02121	5.68e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HCIEDONB_02122	8.54e-277	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HCIEDONB_02123	3.61e-119	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HCIEDONB_02124	7.06e-271	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HCIEDONB_02125	1.6e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HCIEDONB_02126	1.34e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCIEDONB_02127	5.26e-148	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HCIEDONB_02128	4.1e-130	-	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HCIEDONB_02130	1.39e-160	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HCIEDONB_02132	0.0	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HCIEDONB_02133	1.11e-139	-	-	-	-	-	-	-	-
HCIEDONB_02134	2.92e-89	-	-	-	S	-	-	-	response to pH
HCIEDONB_02135	7.57e-134	-	-	-	-	-	-	-	-
HCIEDONB_02136	9.99e-196	ypuA	-	-	S	-	-	-	Secreted protein
HCIEDONB_02137	4.13e-277	-	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HCIEDONB_02138	2.02e-288	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCIEDONB_02139	1.35e-140	gpmB	-	-	G	ko:K15640	-	ko00000	Histidine phosphatase superfamily (branch 1)
HCIEDONB_02140	1.98e-91	-	-	-	K	-	-	-	Transcriptional
HCIEDONB_02141	5.19e-174	-	-	-	L	-	-	-	PFAM Transposase, Mutator
HCIEDONB_02142	2.23e-250	-	-	-	L	-	-	-	Transposase IS4 family protein
HCIEDONB_02143	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02144	8.27e-49	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_02145	7.57e-60	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_02146	6.24e-98	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_02147	3.98e-39	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCIEDONB_02148	1.59e-243	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCIEDONB_02149	1.11e-92	-	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
HCIEDONB_02150	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4277)
HCIEDONB_02151	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase, Cas3
HCIEDONB_02152	2.23e-185	cas5h	-	-	S	ko:K19116	-	ko00000,ko02048	CRISPR-associated protein Cas5
HCIEDONB_02153	1.62e-227	-	-	-	L	ko:K19115	-	ko00000,ko02048	CRISPR-associated protein Cas7
HCIEDONB_02154	0.0	csh	-	-	-	ko:K19114	-	ko00000,ko02048	-
HCIEDONB_02155	1.23e-166	-	-	-	L	ko:K19091	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA)
HCIEDONB_02156	0.0	snf	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HCIEDONB_02157	1.87e-139	-	-	-	C	-	-	-	Nitroreductase family
HCIEDONB_02158	7.63e-117	-	1.8.5.2	-	S	ko:K16937	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	DoxX
HCIEDONB_02159	1.11e-263	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCIEDONB_02160	3.26e-151	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HCIEDONB_02161	1.35e-46	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HCIEDONB_02162	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HCIEDONB_02163	8.81e-266	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_02164	3.83e-22	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HCIEDONB_02165	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HCIEDONB_02166	5.18e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_02167	4.89e-262	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HCIEDONB_02168	3.42e-124	-	-	-	D	-	-	-	Hemerythrin HHE cation binding
HCIEDONB_02169	1.58e-42	-	-	-	-	-	-	-	-
HCIEDONB_02170	2.24e-195	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HCIEDONB_02171	1.16e-76	-	-	-	S	-	-	-	Nitrous oxide-stimulated promoter
HCIEDONB_02172	5e-111	-	-	-	G	ko:K02755,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HCIEDONB_02173	0.0	yfiG	-	-	U	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HCIEDONB_02174	2.72e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HCIEDONB_02176	5.58e-94	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HCIEDONB_02177	2.48e-71	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HCIEDONB_02178	4.05e-73	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HCIEDONB_02179	0.0	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCIEDONB_02180	7.02e-245	yhdN	-	-	C	-	-	-	Aldo keto reductase
HCIEDONB_02182	7.82e-80	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HCIEDONB_02183	4.03e-130	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HCIEDONB_02184	8.74e-235	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase DhaK, subunit
HCIEDONB_02185	6.46e-224	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HCIEDONB_02186	2.7e-176	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HCIEDONB_02187	2.84e-300	-	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HCIEDONB_02188	9.16e-215	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HCIEDONB_02189	3.78e-61	ywdJ	-	-	F	-	-	-	Xanthine uracil
HCIEDONB_02190	1.17e-267	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_02191	2.69e-22	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HCIEDONB_02192	4.97e-192	ywdJ	-	-	F	-	-	-	Xanthine uracil
HCIEDONB_02193	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HCIEDONB_02194	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCIEDONB_02196	1.6e-127	-	-	-	O	-	-	-	HI0933-like protein
HCIEDONB_02199	1.21e-103	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCIEDONB_02200	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HCIEDONB_02201	1.13e-174	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HCIEDONB_02203	3.09e-214	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HCIEDONB_02204	2.15e-22	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HCIEDONB_02205	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HCIEDONB_02206	3.93e-270	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HCIEDONB_02207	0.0	-	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	AMP-dependent synthetase
HCIEDONB_02208	0.0	-	6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCIEDONB_02209	0.0	pspF	-	-	KT	-	-	-	Transcriptional regulator
HCIEDONB_02210	4.28e-121	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HCIEDONB_02211	5.48e-122	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Triosephosphate isomerase
HCIEDONB_02212	7.41e-187	dhaK	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dihydroxyacetone kinase DhaK, subunit
HCIEDONB_02213	4.9e-43	-	2.2.1.10, 4.1.2.13	-	G	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	DeoC/LacD family aldolase
HCIEDONB_02214	1.87e-158	-	4.1.2.28, 4.3.3.7	-	EM	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HCIEDONB_02215	2.87e-89	dhaL	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	S	ko:K00863,ko:K05879	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak2
HCIEDONB_02216	1.57e-214	-	-	-	G	ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HCIEDONB_02217	4.31e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
HCIEDONB_02219	5.65e-172	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HCIEDONB_02221	1.07e-80	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
HCIEDONB_02222	3.67e-125	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCIEDONB_02223	3.66e-139	-	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Bacterial fructose-1,6-bisphosphatase, glpX-encoded
HCIEDONB_02225	5.61e-293	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HCIEDONB_02226	1.88e-307	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HCIEDONB_02227	0.0	lysP	-	-	E	ko:K11733	-	ko00000,ko02000	amino acid
HCIEDONB_02228	4.09e-145	ycfA	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_02229	9.55e-255	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HCIEDONB_02230	1.68e-167	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HCIEDONB_02231	9.11e-92	-	-	-	S	-	-	-	Hemerythrin HHE cation binding domain
HCIEDONB_02232	3.42e-69	-	-	-	-	-	-	-	-
HCIEDONB_02233	3.01e-58	-	-	-	-	-	-	-	-
HCIEDONB_02234	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCIEDONB_02235	0.0	-	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HCIEDONB_02236	2.17e-128	-	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
HCIEDONB_02237	3.24e-156	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	nitrate reductase, gamma subunit
HCIEDONB_02238	3.89e-265	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HCIEDONB_02239	1.58e-207	fda	4.1.2.13	-	G	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	Belongs to the class I fructose-bisphosphate aldolase family
HCIEDONB_02240	2.14e-298	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HCIEDONB_02241	4.29e-56	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02242	1.51e-254	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02243	7.46e-120	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
HCIEDONB_02245	4.13e-309	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02246	0.0	-	-	-	L	-	-	-	Transposase DDE domain group 1
HCIEDONB_02247	0.0	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	AAA domain (dynein-related subfamily)
HCIEDONB_02248	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HCIEDONB_02249	1.64e-103	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
HCIEDONB_02250	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
HCIEDONB_02251	3.02e-36	-	-	-	-	-	-	-	-
HCIEDONB_02252	3.84e-146	-	-	-	E	-	-	-	LysE type translocator
HCIEDONB_02253	6.36e-108	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HCIEDONB_02254	1.21e-103	crr	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HCIEDONB_02255	3.63e-199	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HCIEDONB_02256	3.15e-258	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02257	1.66e-109	-	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HCIEDONB_02258	1.04e-134	-	-	-	L	-	-	-	Integrase
HCIEDONB_02259	0.0	-	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HCIEDONB_02260	1.6e-82	-	-	-	K	ko:K21903	-	ko00000,ko03000	transcriptional
HCIEDONB_02261	1.21e-210	mleR	-	-	K	-	-	-	LysR substrate binding domain
HCIEDONB_02262	6.87e-117	-	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	4Fe-4S single cluster domain
HCIEDONB_02263	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HCIEDONB_02264	1.37e-248	-	-	-	U	-	-	-	protein localization to endoplasmic reticulum
HCIEDONB_02265	2.45e-246	bdhA	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HCIEDONB_02266	1.68e-252	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HCIEDONB_02267	1.72e-268	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_02268	2.02e-268	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_02269	2.69e-22	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HCIEDONB_02270	1.19e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HCIEDONB_02271	3.2e-197	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HCIEDONB_02272	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HCIEDONB_02273	3.65e-90	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCIEDONB_02274	2.25e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCIEDONB_02275	1.59e-226	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HCIEDONB_02276	0.000147	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HCIEDONB_02278	3.63e-05	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_02279	3.33e-211	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_02280	2.67e-116	-	-	-	S	-	-	-	Pyridoxamine 5'phosphate oxidase-like, FMN-binding
HCIEDONB_02281	4.11e-13	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_02282	7e-220	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_02283	4.52e-140	-	-	-	S	-	-	-	Domain of unkown function (DUF1775)
HCIEDONB_02284	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HCIEDONB_02285	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCIEDONB_02286	9.07e-167	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
HCIEDONB_02287	4.81e-228	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HCIEDONB_02288	0.0	-	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HCIEDONB_02289	2.7e-68	-	-	-	-	-	-	-	-
HCIEDONB_02291	1.62e-297	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HCIEDONB_02292	5.88e-277	-	2.3.1.179	-	IQ	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
HCIEDONB_02293	2.13e-152	ureH	-	-	S	-	-	-	PFAM Nickel cobalt transporter, high-affinity
HCIEDONB_02294	1.39e-295	-	-	-	C	-	-	-	Domain of unknown function (DUF2088)
HCIEDONB_02295	2.44e-243	pdxA	1.1.1.408, 1.1.1.409	-	H	ko:K22024	-	ko00000,ko01000	Belongs to the PdxA family
HCIEDONB_02296	2.05e-312	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
HCIEDONB_02297	0.0	-	-	-	K	-	-	-	Propionate catabolism activator
HCIEDONB_02298	1.02e-191	-	-	-	S	ko:K06864	-	ko00000	NAD synthase
HCIEDONB_02299	4.72e-301	-	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HCIEDONB_02301	6.38e-112	-	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HCIEDONB_02302	9.72e-188	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HCIEDONB_02303	4.11e-173	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HCIEDONB_02304	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02305	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_02306	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02307	1.78e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HCIEDONB_02308	2.49e-232	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HCIEDONB_02309	0.0	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HCIEDONB_02310	0.0	estB	-	-	V	-	-	-	Belongs to the UPF0214 family
HCIEDONB_02311	5.16e-309	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_02313	1.58e-96	-	-	-	-	-	-	-	-
HCIEDONB_02314	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HCIEDONB_02315	0.0	yfiB	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HCIEDONB_02316	4.89e-105	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HCIEDONB_02317	3.5e-132	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HCIEDONB_02318	5.51e-158	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HCIEDONB_02319	9.44e-196	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HCIEDONB_02320	1.79e-200	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HCIEDONB_02321	8.98e-263	iolT	-	-	U	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HCIEDONB_02322	1.86e-181	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HCIEDONB_02323	6.04e-259	-	-	-	S	-	-	-	Oxidoreductase
HCIEDONB_02324	1.5e-190	-	-	-	G	-	-	-	Xylose isomerase
HCIEDONB_02325	2.73e-249	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HCIEDONB_02326	1.71e-193	-	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
HCIEDONB_02327	1.12e-258	-	-	-	U	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HCIEDONB_02328	1.77e-157	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCIEDONB_02329	1.13e-164	iolJ	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HCIEDONB_02330	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HCIEDONB_02331	2.77e-186	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HCIEDONB_02332	3.27e-167	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HCIEDONB_02333	2.12e-312	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCIEDONB_02334	3.46e-157	cwlS	-	CBM50	M	ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HCIEDONB_02335	1.28e-77	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HCIEDONB_02336	3.08e-107	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HCIEDONB_02337	4.06e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HCIEDONB_02338	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HCIEDONB_02339	0.0	-	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HCIEDONB_02340	4.79e-229	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HCIEDONB_02341	6.18e-52	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	belongs to the aldehyde dehydrogenase family
HCIEDONB_02342	4.1e-144	-	-	-	P	-	-	-	Integral membrane protein TerC family
HCIEDONB_02343	6.58e-88	-	-	-	-	-	-	-	-
HCIEDONB_02345	2.68e-200	XK27_04815	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HCIEDONB_02346	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HCIEDONB_02347	2.26e-33	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HCIEDONB_02348	1.62e-123	ssuE	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
HCIEDONB_02349	1.14e-175	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HCIEDONB_02350	6.48e-166	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCIEDONB_02351	1.44e-275	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HCIEDONB_02352	1.52e-218	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HCIEDONB_02353	9.16e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCIEDONB_02354	1.45e-05	-	-	-	-	-	-	-	-
HCIEDONB_02355	3.69e-111	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HCIEDONB_02356	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HCIEDONB_02357	5e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HCIEDONB_02358	1.39e-144	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HCIEDONB_02359	2.53e-301	deoA	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HCIEDONB_02360	4.09e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HCIEDONB_02361	4.09e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HCIEDONB_02362	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HCIEDONB_02363	1.27e-271	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HCIEDONB_02364	1.67e-290	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HCIEDONB_02365	1.51e-148	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HCIEDONB_02366	2.83e-213	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HCIEDONB_02367	9.65e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
HCIEDONB_02368	9.67e-174	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HCIEDONB_02369	4.13e-230	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HCIEDONB_02370	1.15e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HCIEDONB_02371	1.89e-274	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HCIEDONB_02372	6.48e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HCIEDONB_02373	1.55e-167	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HCIEDONB_02374	4.82e-147	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HCIEDONB_02375	2.89e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HCIEDONB_02376	6.65e-280	hipO3	-	-	S	ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
HCIEDONB_02377	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HCIEDONB_02378	1.58e-292	-	-	-	M	-	-	-	FFAT motif binding
HCIEDONB_02379	6.6e-124	-	-	-	I	-	-	-	Domain of unknown function (DUF4430)
HCIEDONB_02380	3.34e-120	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HCIEDONB_02381	1.73e-135	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HCIEDONB_02382	8.28e-54	-	-	-	G	-	-	-	PTS system fructose IIA component
HCIEDONB_02383	2.39e-105	-	-	-	-	-	-	-	-
HCIEDONB_02384	3.39e-97	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HCIEDONB_02385	3.09e-159	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HCIEDONB_02386	1.04e-125	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HCIEDONB_02387	1.83e-192	-	-	-	C	ko:K08317	-	ko00000,ko01000	glycerol dehydrogenase
HCIEDONB_02388	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02389	1.29e-10	-	-	-	C	ko:K08317	-	ko00000,ko01000	Iron-containing alcohol dehydrogenase
HCIEDONB_02390	1.2e-183	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HCIEDONB_02391	2.84e-152	-	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase, C-terminal domain
HCIEDONB_02393	1.32e-141	gntR	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HCIEDONB_02394	3.42e-162	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HCIEDONB_02395	1.06e-11	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HCIEDONB_02397	1.16e-145	-	-	-	M	-	-	-	Methyltransferase
HCIEDONB_02398	1.64e-263	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HCIEDONB_02399	1.47e-50	-	-	-	S	-	-	-	Protein of unknown function DUF86
HCIEDONB_02400	9.56e-54	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HCIEDONB_02401	1.42e-245	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HCIEDONB_02403	2.25e-106	-	1.1.1.53	-	IQ	ko:K00038	ko00140,ko01100,map00140,map01100	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEDONB_02404	7.7e-252	-	-	-	L	-	-	-	High confidence in function and specificity
HCIEDONB_02405	4.76e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2750)
HCIEDONB_02406	7.23e-28	mutR	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
HCIEDONB_02407	2.01e-140	-	-	-	EGP	-	-	-	Major Facilitator
HCIEDONB_02408	6.61e-182	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HCIEDONB_02409	1.61e-187	-	-	-	S	-	-	-	Protein of unknown function
HCIEDONB_02410	3.19e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
HCIEDONB_02411	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4277)
HCIEDONB_02412	3.63e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
HCIEDONB_02413	0.0	-	-	-	-	-	-	-	-
HCIEDONB_02414	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02415	1.92e-39	-	-	-	-	-	-	-	-
HCIEDONB_02416	1.66e-304	-	-	-	L	-	-	-	Transposase DDE domain group 1
HCIEDONB_02418	4.27e-186	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PFAM Phosphotransferase system, mannose fructose sorbose family IID component
HCIEDONB_02419	1.59e-173	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HCIEDONB_02420	2.02e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HCIEDONB_02421	9.99e-93	-	-	-	G	-	-	-	PTS system fructose IIA component
HCIEDONB_02422	2.04e-314	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02423	2.94e-194	-	-	-	U	-	-	-	AAA domain
HCIEDONB_02424	0.0	-	-	-	L	-	-	-	Mu transposase, C-terminal
HCIEDONB_02426	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02427	3.25e-78	-	-	-	K	ko:K19505	-	ko00000,ko03000	PFAM sigma-54 factor interaction domain-containing protein
HCIEDONB_02428	0.0	-	-	-	K	ko:K19505	-	ko00000,ko03000	PTS system fructose IIA component
HCIEDONB_02429	7.39e-56	-	-	-	K	ko:K19505	-	ko00000,ko03000	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HCIEDONB_02430	7.04e-13	-	-	-	L	ko:K07494	-	ko00000	DDE superfamily endonuclease
HCIEDONB_02432	1.05e-68	-	-	-	Q	-	-	-	Isochorismatase family
HCIEDONB_02433	1.65e-122	-	-	-	S	-	-	-	S4 RNA-binding domain
HCIEDONB_02434	1.63e-235	-	-	-	-	-	-	-	-
HCIEDONB_02435	1.33e-66	yxjI	-	-	S	-	-	-	LURP-one-related
HCIEDONB_02436	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCIEDONB_02437	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCIEDONB_02438	1.95e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HCIEDONB_02439	3.88e-199	-	-	-	Q	-	-	-	N-acetyltransferase
HCIEDONB_02441	4.74e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HCIEDONB_02443	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCIEDONB_02444	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCIEDONB_02445	2.67e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCIEDONB_02446	4.12e-313	aceA	4.1.3.1	-	C	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Isocitrate lyase
HCIEDONB_02447	0.0	aceB	2.3.3.9	-	C	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the malate synthase family
HCIEDONB_02448	1.18e-275	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HCIEDONB_02449	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCIEDONB_02450	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HCIEDONB_02451	6.38e-167	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HCIEDONB_02452	4.29e-70	yerC	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_02453	1.08e-242	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HCIEDONB_02454	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HCIEDONB_02455	3.43e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HCIEDONB_02456	2.16e-283	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HCIEDONB_02457	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HCIEDONB_02458	6.71e-134	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCIEDONB_02459	3.33e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HCIEDONB_02460	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCIEDONB_02461	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCIEDONB_02462	9.08e-165	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCIEDONB_02463	7.94e-54	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCIEDONB_02464	8.29e-161	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HCIEDONB_02465	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCIEDONB_02466	4.49e-279	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCIEDONB_02467	8.48e-106	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCIEDONB_02468	3.36e-42	yebG	-	-	S	-	-	-	NETI protein
HCIEDONB_02469	1.09e-117	yebE	-	-	S	-	-	-	UPF0316 protein
HCIEDONB_02470	6.13e-175	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	dithiol-disulfide isomerase involved in polyketide biosynthesis
HCIEDONB_02471	9.4e-57	-	-	-	-	-	-	-	-
HCIEDONB_02472	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HCIEDONB_02473	7.54e-284	gltT	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCIEDONB_02474	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCIEDONB_02475	3.05e-199	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HCIEDONB_02476	1.5e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HCIEDONB_02477	0.000343	-	-	-	D	-	-	-	nuclear chromosome segregation
HCIEDONB_02478	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HCIEDONB_02479	2.02e-271	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HCIEDONB_02480	2.8e-150	yfiK	-	-	K	-	-	-	Regulator
HCIEDONB_02481	5.61e-252	-	-	-	T	-	-	-	Histidine kinase
HCIEDONB_02482	3.21e-216	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HCIEDONB_02483	2.67e-252	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HCIEDONB_02484	6.19e-263	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HCIEDONB_02485	4.79e-245	-	1.13.11.4	-	Q	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	ko00000,ko00001,ko01000	Cupin domain
HCIEDONB_02486	2.32e-197	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_02487	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_02488	3.8e-108	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_02490	0.0	citT_1	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HCIEDONB_02491	5.95e-63	-	-	-	L	-	-	-	deoxyribonuclease I activity
HCIEDONB_02492	0.0	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCIEDONB_02494	5.15e-91	-	-	-	-	-	-	-	-
HCIEDONB_02495	3.96e-163	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCIEDONB_02496	5.59e-78	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_02497	6.51e-122	padR	-	-	K	-	-	-	transcriptional
HCIEDONB_02498	4.57e-124	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HCIEDONB_02499	7.47e-148	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HCIEDONB_02500	1.17e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_02501	3.16e-112	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCIEDONB_02502	2.59e-212	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCIEDONB_02503	2.72e-50	lysE	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HCIEDONB_02504	1e-195	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_02505	1.21e-48	yeeD	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
HCIEDONB_02506	8.23e-247	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
HCIEDONB_02507	1.78e-308	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HCIEDONB_02508	9.68e-221	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEDONB_02509	1.77e-10	-	-	-	-	ko:K07213	ko04978,map04978	ko00000,ko00001	-
HCIEDONB_02510	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
HCIEDONB_02511	1.25e-241	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HCIEDONB_02512	6.61e-180	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCIEDONB_02513	2.32e-239	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEDONB_02514	1.31e-121	-	-	-	-	-	-	-	-
HCIEDONB_02516	8.67e-233	-	-	-	P	-	-	-	Major facilitator superfamily
HCIEDONB_02517	5.26e-15	-	-	-	EGP	-	-	-	Major facilitator superfamily
HCIEDONB_02518	9.99e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HCIEDONB_02519	9.48e-43	-	-	-	-	-	-	-	-
HCIEDONB_02520	4.08e-43	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HCIEDONB_02521	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HCIEDONB_02522	7.49e-197	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCIEDONB_02523	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCIEDONB_02524	1.14e-139	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HCIEDONB_02525	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_02526	3.02e-254	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HCIEDONB_02527	0.0	ykoS	-	-	-	-	-	-	-
HCIEDONB_02528	1.84e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HCIEDONB_02529	1.5e-88	yngA	-	-	S	-	-	-	GtrA-like protein
HCIEDONB_02530	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCIEDONB_02531	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCIEDONB_02532	6.51e-161	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HCIEDONB_02533	2.21e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HCIEDONB_02534	2.26e-167	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HCIEDONB_02535	1.97e-159	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCIEDONB_02537	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HCIEDONB_02538	3.3e-236	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCIEDONB_02539	1.35e-106	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HCIEDONB_02540	5.03e-165	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HCIEDONB_02541	1.41e-108	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HCIEDONB_02543	9.4e-57	-	-	-	-	-	-	-	-
HCIEDONB_02544	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HCIEDONB_02557	1.09e-120	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HCIEDONB_02558	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HCIEDONB_02559	9.22e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HCIEDONB_02560	2.37e-176	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEDONB_02561	8.05e-106	rsbW	2.7.11.1	-	T	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HCIEDONB_02562	5.11e-80	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HCIEDONB_02563	1.65e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HCIEDONB_02564	5.15e-91	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HCIEDONB_02565	3.41e-73	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HCIEDONB_02566	1.24e-195	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HCIEDONB_02567	1.25e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HCIEDONB_02568	1.47e-55	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HCIEDONB_02569	8.36e-278	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCIEDONB_02570	4.94e-245	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HCIEDONB_02571	5.48e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCIEDONB_02572	3.46e-137	ydcA	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
HCIEDONB_02573	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCIEDONB_02574	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02575	3.66e-82	-	-	-	-	-	-	-	-
HCIEDONB_02576	3.56e-138	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HCIEDONB_02577	6.6e-158	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HCIEDONB_02578	6.84e-226	yvdE	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_02579	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HCIEDONB_02580	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
HCIEDONB_02581	4.79e-311	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HCIEDONB_02582	7.1e-310	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HCIEDONB_02583	9.8e-197	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HCIEDONB_02584	6.02e-185	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HCIEDONB_02585	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
HCIEDONB_02586	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HCIEDONB_02587	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCIEDONB_02588	9.1e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HCIEDONB_02589	5.71e-192	-	-	-	-	-	-	-	-
HCIEDONB_02590	5.74e-301	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HCIEDONB_02591	1.34e-108	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HCIEDONB_02592	0.0	-	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HCIEDONB_02594	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HCIEDONB_02595	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HCIEDONB_02597	3.69e-92	ywpF	-	-	S	-	-	-	YwpF-like protein
HCIEDONB_02598	5.41e-84	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HCIEDONB_02600	4.3e-96	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCIEDONB_02601	1.5e-192	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HCIEDONB_02602	9.06e-187	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HCIEDONB_02603	4.13e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HCIEDONB_02605	3.27e-57	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HCIEDONB_02606	7.35e-174	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HCIEDONB_02607	4.86e-235	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HCIEDONB_02608	8.89e-305	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCIEDONB_02609	2.39e-174	ywmB	-	-	S	-	-	-	TATA-box binding
HCIEDONB_02610	1.1e-46	ywzB	-	-	S	-	-	-	membrane
HCIEDONB_02611	1.03e-87	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HCIEDONB_02612	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCIEDONB_02613	4.28e-192	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCIEDONB_02614	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCIEDONB_02615	6.07e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCIEDONB_02616	1.46e-68	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCIEDONB_02617	1.21e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCIEDONB_02618	4.65e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HCIEDONB_02619	1.2e-69	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase I chain
HCIEDONB_02620	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCIEDONB_02621	1.41e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCIEDONB_02622	1.66e-304	-	-	-	L	-	-	-	Transposase DDE domain group 1
HCIEDONB_02623	2.1e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HCIEDONB_02624	1.04e-103	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HCIEDONB_02625	3.19e-271	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Chemotaxis
HCIEDONB_02626	1.36e-105	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCIEDONB_02627	2.36e-118	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HCIEDONB_02628	2.57e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCIEDONB_02629	1.87e-170	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HCIEDONB_02630	4.34e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCIEDONB_02631	4.23e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCIEDONB_02633	4.8e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HCIEDONB_02634	2.24e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HCIEDONB_02635	7.11e-293	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCIEDONB_02636	1.74e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HCIEDONB_02637	1.79e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCIEDONB_02638	1.51e-148	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCIEDONB_02639	1.58e-203	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HCIEDONB_02640	2.03e-80	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
HCIEDONB_02641	1.76e-278	-	-	-	-	-	-	-	-
HCIEDONB_02642	1.56e-190	-	-	-	-	-	-	-	-
HCIEDONB_02643	2.05e-162	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCIEDONB_02644	8.23e-88	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HCIEDONB_02645	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCIEDONB_02646	9.54e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCIEDONB_02647	6.37e-160	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCIEDONB_02648	0.0	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HCIEDONB_02649	0.0	icmF	5.4.99.13	-	EI	ko:K11942	-	ko00000,ko01000	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HCIEDONB_02650	1.66e-32	icmF	5.4.99.13	-	EI	ko:K11942	-	ko00000,ko01000	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HCIEDONB_02651	1.24e-145	kstR2_2	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_02652	2.03e-272	acdA	1.3.8.1, 1.3.8.7	-	I	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	acyl-CoA dehydrogenase
HCIEDONB_02653	6.5e-268	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HCIEDONB_02654	1.62e-275	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
HCIEDONB_02655	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HCIEDONB_02656	2.05e-277	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HCIEDONB_02657	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HCIEDONB_02658	6.52e-98	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_02659	2.87e-213	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HCIEDONB_02660	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HCIEDONB_02661	2.16e-119	ywhD	-	-	S	-	-	-	YwhD family
HCIEDONB_02662	2.8e-151	ywhC	-	-	S	-	-	-	Peptidase M50
HCIEDONB_02663	2.69e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HCIEDONB_02664	2.42e-117	ywgA	-	-	-	ko:K09388	-	ko00000	-
HCIEDONB_02665	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HCIEDONB_02667	3.35e-140	rsfA	-	-	S	ko:K06314	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_02668	2.4e-194	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HCIEDONB_02669	3.02e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HCIEDONB_02670	9.48e-188	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HCIEDONB_02671	1.26e-105	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HCIEDONB_02672	1.86e-77	ywdK	-	-	S	-	-	-	small membrane protein
HCIEDONB_02673	1.53e-46	-	-	-	S	-	-	-	Family of unknown function (DUF5327)
HCIEDONB_02674	1.57e-170	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCIEDONB_02675	5.3e-71	-	-	-	S	-	-	-	Heat induced stress protein YflT
HCIEDONB_02676	3.71e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCIEDONB_02677	1.75e-198	-	-	-	L	-	-	-	Archaeal putative transposase ISC1217
HCIEDONB_02678	1.74e-26	-	-	-	S	-	-	-	Circ_ocin_uber circular bacteriocin, circularin A uberolysin family protein
HCIEDONB_02679	0.0	-	-	-	-	-	-	-	-
HCIEDONB_02680	1.38e-54	-	-	-	S	-	-	-	Stage II sporulation protein M
HCIEDONB_02681	3.74e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCIEDONB_02684	1.36e-130	-	-	-	S	-	-	-	ABC-2 family transporter protein
HCIEDONB_02685	8.32e-138	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HCIEDONB_02686	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_02688	2.14e-262	-	-	-	-	-	-	-	-
HCIEDONB_02689	9.44e-194	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HCIEDONB_02690	9.13e-81	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HCIEDONB_02691	4.69e-167	bshB2	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HCIEDONB_02692	3.59e-206	ycsE	-	-	S	-	-	-	hydrolases of the HAD superfamily
HCIEDONB_02693	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HCIEDONB_02694	2.15e-298	phoA	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HCIEDONB_02695	4.01e-200	murR	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_02696	1.18e-195	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCIEDONB_02697	1.73e-19	-	-	-	-	-	-	-	-
HCIEDONB_02698	7.86e-97	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCIEDONB_02700	1.43e-152	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HCIEDONB_02701	4.35e-77	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HCIEDONB_02702	3.16e-233	ywbI	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_02703	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HCIEDONB_02704	2.19e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF1646)
HCIEDONB_02706	0.0	-	-	-	L	-	-	-	Transposase
HCIEDONB_02707	3.75e-98	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HCIEDONB_02708	5.6e-170	yjjP	-	-	S	-	-	-	Putative threonine/serine exporter
HCIEDONB_02709	3.87e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HCIEDONB_02710	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HCIEDONB_02711	1.82e-165	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HCIEDONB_02712	0.0	lytS	2.7.13.3	-	T	ko:K02478,ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCIEDONB_02714	1.29e-195	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HCIEDONB_02715	2.47e-145	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HCIEDONB_02716	1.86e-244	metN_1	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCIEDONB_02717	5.43e-182	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HCIEDONB_02718	2.55e-130	-	-	-	-	-	-	-	-
HCIEDONB_02719	3.18e-282	-	-	-	NU	ko:K18640	-	ko00000,ko04812	Pilus assembly protein
HCIEDONB_02720	7.44e-295	yisQ	-	-	V	-	-	-	Mate efflux family protein
HCIEDONB_02721	9.44e-190	gspA	-	-	M	-	-	-	Glycosyl transferase family 8
HCIEDONB_02722	2.81e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HCIEDONB_02723	0.0	-	-	-	EGP	-	-	-	the major facilitator superfamily
HCIEDONB_02724	6.98e-285	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HCIEDONB_02725	0.0	poxB	1.2.5.1	-	EH	ko:K00156	ko00620,map00620	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HCIEDONB_02726	2.46e-289	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
HCIEDONB_02727	1.72e-213	-	-	-	L	-	-	-	Transposase DDE domain group 1
HCIEDONB_02728	1.23e-34	-	-	-	O	-	-	-	cellulase activity
HCIEDONB_02729	7.55e-261	ugpC	3.6.3.20	-	P	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HCIEDONB_02730	1.58e-212	ugpA	-	-	G	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HCIEDONB_02731	7.14e-189	ugpE	-	-	P	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter permease
HCIEDONB_02733	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter substrate-binding protein
HCIEDONB_02734	1.24e-190	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HCIEDONB_02735	1.79e-130	-	-	-	S	-	-	-	Domain of unknown function (DUF2935)
HCIEDONB_02737	0.0	-	-	-	M	ko:K20276	ko02024,map02024	ko00000,ko00001	Non-essential cell division protein that could be required for efficient cell constriction
HCIEDONB_02738	3.58e-27	-	-	-	O	ko:K20276	ko02024,map02024	ko00000,ko00001	M6 family metalloprotease domain protein
HCIEDONB_02739	7.09e-253	-	-	-	L	ko:K07486	-	ko00000	Transposase IS116/IS110/IS902 family
HCIEDONB_02740	1.6e-245	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_02741	8.9e-56	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_02742	1.6e-140	yhhQ_2	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HCIEDONB_02743	9.24e-128	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HCIEDONB_02744	0.0	-	-	-	S	ko:K06994,ko:K07003	-	ko00000	MMPL domain protein
HCIEDONB_02745	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HCIEDONB_02746	4.71e-56	-	-	-	T	-	-	-	diguanylate cyclase activity
HCIEDONB_02747	6.63e-174	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HCIEDONB_02748	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HCIEDONB_02749	7.57e-210	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HCIEDONB_02750	1.76e-303	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase
HCIEDONB_02751	8.75e-285	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
HCIEDONB_02752	4.18e-263	-	-	-	S	-	-	-	Domain of unknown function (DUF1611_N) Rossmann-like domain
HCIEDONB_02753	5.02e-276	-	-	-	E	-	-	-	Alanine racemase, N-terminal domain
HCIEDONB_02754	5.03e-193	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HCIEDONB_02755	1.96e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCIEDONB_02756	7.93e-151	glnP7	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	amino acid ABC transporter
HCIEDONB_02757	3.96e-146	glnP9	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	amino acid ABC transporter
HCIEDONB_02758	0.0	mqo	1.1.5.4	-	S	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	malate quinone oxidoreductase
HCIEDONB_02759	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HCIEDONB_02760	1.47e-86	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HCIEDONB_02761	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
HCIEDONB_02762	1.58e-139	-	-	-	-	-	-	-	-
HCIEDONB_02763	3.95e-103	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCIEDONB_02764	7.53e-283	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCIEDONB_02765	3.54e-185	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HCIEDONB_02766	5.87e-182	yycI	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_02767	3.89e-316	yycH	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_02768	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCIEDONB_02769	5.26e-173	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEDONB_02773	1.69e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCIEDONB_02774	1.84e-316	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HCIEDONB_02775	9.21e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HCIEDONB_02776	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HCIEDONB_02777	2.54e-198	yybS	-	-	S	-	-	-	membrane
HCIEDONB_02778	7.33e-50	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCIEDONB_02779	1.66e-107	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCIEDONB_02780	3.01e-63	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HCIEDONB_02781	5.44e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HCIEDONB_02782	3.86e-281	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HCIEDONB_02783	2.6e-149	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HCIEDONB_02784	9.56e-266	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCIEDONB_02785	1.51e-260	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCIEDONB_02786	3.73e-44	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_02787	1.7e-207	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HCIEDONB_02788	1.52e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HCIEDONB_02789	1.16e-152	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HCIEDONB_02790	3.79e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HCIEDONB_02791	6.81e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HCIEDONB_02792	2.69e-195	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HCIEDONB_02793	1.97e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HCIEDONB_02794	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCIEDONB_02795	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCIEDONB_02796	2.94e-142	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HCIEDONB_02797	5.78e-174	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCIEDONB_02798	7.56e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCIEDONB_02799	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCIEDONB_02800	1.7e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCIEDONB_02801	1.4e-44	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HCIEDONB_02802	1.77e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCIEDONB_02803	9.35e-16	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HCIEDONB_02804	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCIEDONB_02805	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCIEDONB_02806	1.38e-251	M1-161	-	-	T	-	-	-	HD domain
HCIEDONB_02807	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HCIEDONB_02810	9.4e-57	-	-	-	-	-	-	-	-
HCIEDONB_02811	6.44e-49	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HCIEDONB_02812	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HCIEDONB_02813	2.41e-155	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCIEDONB_02814	3.54e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_02815	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HCIEDONB_02816	1.99e-237	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HCIEDONB_02817	3.27e-191	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HCIEDONB_02818	1.06e-87	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HCIEDONB_02819	2.49e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HCIEDONB_02820	3.38e-63	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HCIEDONB_02821	1.47e-208	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCIEDONB_02822	6.07e-77	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HCIEDONB_02823	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCIEDONB_02824	1.7e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HCIEDONB_02825	9.16e-138	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCIEDONB_02826	2.94e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCIEDONB_02827	1.66e-213	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HCIEDONB_02828	8.34e-51	veg	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_02829	4.78e-46	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HCIEDONB_02830	6.21e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCIEDONB_02831	1.24e-198	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HCIEDONB_02832	8.83e-81	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HCIEDONB_02833	2.1e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HCIEDONB_02835	1.7e-185	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCIEDONB_02836	3.85e-108	-	-	-	L	-	-	-	Transposase
HCIEDONB_02837	7.26e-55	-	-	-	L	-	-	-	Transposase, IS4 family protein
HCIEDONB_02838	1.53e-26	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCIEDONB_02839	2.6e-82	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HCIEDONB_02840	2.83e-104	-	-	-	-	-	-	-	-
HCIEDONB_02841	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCIEDONB_02842	1.32e-224	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCIEDONB_02843	5.06e-144	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HCIEDONB_02844	1.38e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCIEDONB_02845	1.79e-50	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HCIEDONB_02846	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCIEDONB_02847	1.62e-118	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HCIEDONB_02848	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCIEDONB_02849	8.25e-249	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HCIEDONB_02850	1.58e-55	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HCIEDONB_02851	1.23e-67	yabP	-	-	S	-	-	-	Sporulation protein YabP
HCIEDONB_02852	2.41e-142	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HCIEDONB_02853	7.06e-79	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HCIEDONB_02854	7.71e-85	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HCIEDONB_02856	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HCIEDONB_02857	9.97e-162	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HCIEDONB_02858	3.24e-225	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HCIEDONB_02859	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCIEDONB_02860	3.38e-122	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HCIEDONB_02861	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCIEDONB_02862	2e-205	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HCIEDONB_02863	5.07e-204	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCIEDONB_02864	6.25e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HCIEDONB_02865	3.2e-204	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HCIEDONB_02866	3.1e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCIEDONB_02867	8.14e-125	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HCIEDONB_02868	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HCIEDONB_02869	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HCIEDONB_02870	1.39e-58	-	-	-	-	-	-	-	-
HCIEDONB_02878	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HCIEDONB_02879	5.65e-58	-	-	-	-	-	-	-	-
HCIEDONB_02880	1.91e-233	yaaC	-	-	S	-	-	-	YaaC-like Protein
HCIEDONB_02881	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HCIEDONB_02882	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HCIEDONB_02883	9.82e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HCIEDONB_02884	6.53e-133	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HCIEDONB_02885	7.45e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCIEDONB_02886	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_02888	5.93e-163	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HCIEDONB_02889	2.33e-155	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HCIEDONB_02890	1.69e-292	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HCIEDONB_02892	3.07e-114	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCIEDONB_02893	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCIEDONB_02894	1.82e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCIEDONB_02895	4.93e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCIEDONB_02896	1.29e-10	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HCIEDONB_02897	1.98e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HCIEDONB_02898	8.58e-10	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HCIEDONB_02899	2.86e-267	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_02900	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HCIEDONB_02903	1.39e-58	-	-	-	-	-	-	-	-
HCIEDONB_02904	6.38e-97	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HCIEDONB_02905	3.03e-129	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HCIEDONB_02906	7.89e-246	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HCIEDONB_02907	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HCIEDONB_02908	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCIEDONB_02909	3.52e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HCIEDONB_02910	3.12e-151	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HCIEDONB_02911	5.64e-107	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HCIEDONB_02912	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCIEDONB_02913	3.55e-155	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HCIEDONB_02914	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HCIEDONB_02915	7.96e-91	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCIEDONB_02916	1.75e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCIEDONB_02917	7.49e-117	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HCIEDONB_02918	1.75e-143	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HCIEDONB_02919	5.24e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCIEDONB_02920	5.67e-123	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HCIEDONB_02921	2.39e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCIEDONB_02922	1.62e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCIEDONB_02924	8.48e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCIEDONB_02925	2.76e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCIEDONB_02926	5.13e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HCIEDONB_02927	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCIEDONB_02928	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCIEDONB_02929	9.09e-50	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HCIEDONB_02930	4.16e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCIEDONB_02931	3.41e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCIEDONB_02932	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCIEDONB_02933	1.25e-285	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCIEDONB_02934	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_02935	1.82e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HCIEDONB_02936	1.51e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCIEDONB_02937	3.29e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HCIEDONB_02938	4.16e-56	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCIEDONB_02939	2.07e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCIEDONB_02940	9.87e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCIEDONB_02941	1.59e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCIEDONB_02942	7.14e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCIEDONB_02943	2.03e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCIEDONB_02944	2.44e-36	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HCIEDONB_02945	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCIEDONB_02946	1.48e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCIEDONB_02947	2.15e-75	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCIEDONB_02948	9.01e-121	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCIEDONB_02949	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCIEDONB_02950	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCIEDONB_02951	7.45e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCIEDONB_02952	1.22e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCIEDONB_02953	5.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCIEDONB_02954	2.65e-32	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HCIEDONB_02955	3.48e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HCIEDONB_02956	1.14e-292	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCIEDONB_02957	3.31e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCIEDONB_02958	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCIEDONB_02959	6.28e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCIEDONB_02960	9.37e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCIEDONB_02961	9.96e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCIEDONB_02962	8.7e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HCIEDONB_02964	8.45e-202	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCIEDONB_02965	4.72e-207	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCIEDONB_02966	2.18e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCIEDONB_02967	3.42e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCIEDONB_02968	2.28e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCIEDONB_02969	1.05e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HCIEDONB_02970	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HCIEDONB_02971	1.48e-236	-	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HCIEDONB_02972	9.5e-182	-	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HCIEDONB_02974	2.35e-289	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HCIEDONB_02975	6.73e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HCIEDONB_02976	0.0	lysP	-	-	E	ko:K11733	-	ko00000,ko02000	amino acid
HCIEDONB_02977	1.73e-107	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HCIEDONB_02978	2.59e-169	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HCIEDONB_02979	1.82e-253	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HCIEDONB_02980	1.26e-118	gerD	-	-	S	ko:K06294	-	ko00000	Spore gernimation protein
HCIEDONB_02981	1.42e-131	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HCIEDONB_02982	1.13e-271	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_02983	1.42e-83	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HCIEDONB_02984	9.93e-269	-	-	-	S	-	-	-	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
HCIEDONB_02985	1.81e-223	-	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_02986	3.38e-73	-	-	-	G	-	-	-	Cupin domain
HCIEDONB_02987	5.04e-99	-	-	-	-	-	-	-	-
HCIEDONB_02988	1.69e-174	pdaB	-	-	G	-	-	-	xylanase chitin deacetylase
HCIEDONB_02989	1.37e-41	-	-	-	-	-	-	-	-
HCIEDONB_02990	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HCIEDONB_02991	6.34e-231	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HCIEDONB_02992	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HCIEDONB_02993	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HCIEDONB_02994	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HCIEDONB_02995	1.39e-58	-	-	-	-	-	-	-	-
HCIEDONB_03005	1.39e-163	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HCIEDONB_03006	2.17e-92	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HCIEDONB_03008	3.19e-41	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HCIEDONB_03009	2.36e-36	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCIEDONB_03010	1.64e-19	-	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
HCIEDONB_03011	3.67e-73	-	-	-	S	-	-	-	DNA binding
HCIEDONB_03012	1.49e-21	-	-	-	S	-	-	-	Helix-turn-helix domain
HCIEDONB_03018	5.29e-173	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HCIEDONB_03019	3.3e-159	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HCIEDONB_03020	7.7e-37	-	-	-	L	-	-	-	Replication initiation and membrane attachment
HCIEDONB_03021	2e-114	-	-	-	L	-	-	-	Bacterial dnaA protein
HCIEDONB_03025	1.09e-61	-	-	-	S	-	-	-	dUTPase
HCIEDONB_03026	7.73e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HCIEDONB_03029	3.62e-24	-	-	-	-	-	-	-	-
HCIEDONB_03030	6.44e-85	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HCIEDONB_03032	5.14e-08	-	-	-	-	-	-	-	-
HCIEDONB_03033	4.37e-48	yqaQ	-	-	L	-	-	-	Transposase
HCIEDONB_03034	6.02e-237	-	-	-	KL	-	-	-	PFAM DNA methylase N-4 N-6 domain protein
HCIEDONB_03035	1.59e-36	-	-	-	-	-	-	-	-
HCIEDONB_03036	4.55e-110	-	-	-	-	-	-	-	-
HCIEDONB_03037	3.61e-253	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
HCIEDONB_03038	4.2e-192	-	-	-	S	-	-	-	portal protein
HCIEDONB_03039	3.06e-160	-	-	-	M	-	-	-	Phage minor capsid protein 2
HCIEDONB_03040	2.76e-28	-	-	-	-	-	-	-	-
HCIEDONB_03041	1.61e-44	-	-	-	-	-	-	-	-
HCIEDONB_03042	5.56e-156	-	-	-	-	-	-	-	-
HCIEDONB_03043	3.2e-20	-	-	-	-	-	-	-	-
HCIEDONB_03046	1.07e-37	-	-	-	S	-	-	-	Minor capsid protein
HCIEDONB_03047	3.06e-50	-	-	-	S	-	-	-	Minor capsid protein from bacteriophage
HCIEDONB_03048	1.22e-62	-	-	-	N	-	-	-	Belongs to the glycosyl hydrolase family 6
HCIEDONB_03050	4.75e-66	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
HCIEDONB_03051	1.16e-151	-	-	-	L	-	-	-	Transglycosylase SLT domain
HCIEDONB_03052	1.47e-202	-	-	-	S	-	-	-	Phage tail protein
HCIEDONB_03053	5.16e-63	-	-	-	S	-	-	-	Phage minor structural protein
HCIEDONB_03054	1.09e-103	-	-	-	-	-	-	-	-
HCIEDONB_03057	1.71e-51	-	-	-	-	-	-	-	-
HCIEDONB_03059	3.29e-153	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HCIEDONB_03062	4.94e-214	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HCIEDONB_03064	3.78e-126	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HCIEDONB_03065	1.36e-150	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HCIEDONB_03067	6.33e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCIEDONB_03068	4.36e-283	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_03069	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCIEDONB_03070	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCIEDONB_03072	3.32e-129	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
HCIEDONB_03073	2.41e-185	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HCIEDONB_03075	3.7e-275	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HCIEDONB_03076	1.29e-259	-	-	-	EGP	-	-	-	COG2814 Arabinose efflux permease
HCIEDONB_03077	6.28e-84	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HCIEDONB_03078	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_03079	3.05e-108	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HCIEDONB_03080	1.02e-178	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HCIEDONB_03081	0.0	-	-	-	NT	ko:K03406,ko:K06595	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Chemoreceptor zinc-binding domain
HCIEDONB_03082	1.05e-153	-	-	-	S	-	-	-	Putative adhesin
HCIEDONB_03083	1.08e-120	XK27_04830	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HCIEDONB_03084	5.08e-72	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
HCIEDONB_03085	7.93e-278	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HCIEDONB_03086	0.0	-	-	-	EGP	-	-	-	Major facilitator superfamily
HCIEDONB_03087	1.37e-129	-	-	-	Q	-	-	-	Isochorismatase family
HCIEDONB_03088	1.52e-136	-	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_03089	7.19e-48	-	-	-	-	-	-	-	-
HCIEDONB_03090	3.11e-160	-	-	-	-	-	-	-	-
HCIEDONB_03091	5.64e-59	ltaA	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	L-allo-threonine aldolase activity
HCIEDONB_03092	3.19e-264	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCIEDONB_03093	5.81e-218	-	-	-	F	-	-	-	ATP-grasp domain
HCIEDONB_03094	1.71e-264	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HCIEDONB_03095	6.93e-63	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HCIEDONB_03096	1.4e-236	ywcH1	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCIEDONB_03098	8.64e-275	-	-	-	G	-	-	-	Major Facilitator Superfamily
HCIEDONB_03099	6.88e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HCIEDONB_03101	6.05e-113	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HCIEDONB_03102	8.53e-95	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
HCIEDONB_03104	3.47e-89	-	-	-	E	-	-	-	lactoylglutathione lyase activity
HCIEDONB_03105	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_03106	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_03107	1.82e-294	lmrP	-	-	E	ko:K08152	-	ko00000,ko02000	Transmembrane secretion effector
HCIEDONB_03108	1.32e-97	yycN	-	-	K	-	-	-	FR47-like protein
HCIEDONB_03109	8.96e-92	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HCIEDONB_03110	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4277)
HCIEDONB_03111	3.86e-66	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HCIEDONB_03112	4.9e-158	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HCIEDONB_03113	4.75e-07	-	-	-	-	-	-	-	-
HCIEDONB_03114	1.01e-290	mvaA	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Hydroxymethylglutaryl-coenzyme A reductase
HCIEDONB_03115	5.24e-281	mvaS	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HCIEDONB_03116	1.05e-271	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HCIEDONB_03117	2.99e-71	-	-	-	S	-	-	-	DsrE/DsrF-like family
HCIEDONB_03118	7.5e-100	-	-	-	-	-	-	-	-
HCIEDONB_03119	2.07e-235	-	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIEDONB_03121	3.8e-225	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HCIEDONB_03122	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HCIEDONB_03123	5.39e-106	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HCIEDONB_03124	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCIEDONB_03125	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HCIEDONB_03126	2.13e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HCIEDONB_03127	5.23e-295	-	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HCIEDONB_03129	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HCIEDONB_03130	6.36e-162	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
HCIEDONB_03131	4.78e-218	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
HCIEDONB_03132	1.07e-104	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HCIEDONB_03133	3.15e-255	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCIEDONB_03134	1.02e-177	-	-	-	T	ko:K21562	-	ko00000,ko03000	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HCIEDONB_03135	0.0	-	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HCIEDONB_03136	7.15e-43	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HCIEDONB_03138	0.0	nrdA	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCIEDONB_03139	4.41e-113	-	-	-	C	-	-	-	Flavodoxin
HCIEDONB_03140	3.79e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCIEDONB_03141	5.73e-143	-	-	-	I	-	-	-	Belongs to the PlsY family
HCIEDONB_03142	4.53e-264	crtQ	-	-	M	ko:K10211	ko00906,map00906	ko00000,ko00001,ko01000	Glycosyl transferase family 21
HCIEDONB_03143	5.23e-205	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_03144	1.14e-27	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_03145	3.26e-25	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_03146	1.8e-120	-	-	-	Q	-	-	-	Thioesterase superfamily
HCIEDONB_03147	5.18e-221	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HCIEDONB_03148	8.58e-65	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HCIEDONB_03149	2.27e-71	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HCIEDONB_03150	2.67e-178	yfcA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HCIEDONB_03151	4.84e-233	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEDONB_03152	1.68e-232	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEDONB_03153	1.13e-225	fhuD9	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HCIEDONB_03154	5.06e-193	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCIEDONB_03155	2.89e-251	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HCIEDONB_03156	1.98e-147	-	-	-	-	-	-	-	-
HCIEDONB_03157	2.69e-145	-	-	-	-	-	-	-	-
HCIEDONB_03158	3.77e-139	-	-	-	-	-	-	-	-
HCIEDONB_03159	1.96e-165	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HCIEDONB_03160	7.59e-245	-	-	-	T	ko:K17763	-	ko00000,ko03021	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
HCIEDONB_03161	5.12e-306	bbsG	1.3.8.7	-	I	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	COG1960 Acyl-CoA dehydrogenases
HCIEDONB_03162	2.37e-175	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEDONB_03163	1.87e-221	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCIEDONB_03164	5.9e-91	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCIEDONB_03165	2.1e-123	-	-	-	K	-	-	-	Transcriptional regulator
HCIEDONB_03166	2.01e-67	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HCIEDONB_03167	1.77e-261	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HCIEDONB_03168	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCIEDONB_03169	1.07e-127	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HCIEDONB_03170	1.29e-107	-	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HCIEDONB_03171	4.57e-142	-	3.6.3.21	-	E	ko:K02028,ko:K10038	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCIEDONB_03172	2.43e-290	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
HCIEDONB_03173	6.67e-183	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HCIEDONB_03174	9.06e-182	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HCIEDONB_03175	1.53e-161	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HCIEDONB_03176	2.46e-130	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HCIEDONB_03177	1.83e-123	ywhH	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HCIEDONB_03178	1.99e-261	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HCIEDONB_03179	0.0	-	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCIEDONB_03180	1.78e-242	-	-	-	T	ko:K20971	ko02025,map02025	ko00000,ko00001,ko01001,ko02022	Diguanylate cyclase, GGDEF domain
HCIEDONB_03182	2.46e-219	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HCIEDONB_03183	7.95e-220	-	-	-	S	-	-	-	Nuclease-related domain
HCIEDONB_03184	4.98e-25	-	-	-	-	-	-	-	-
HCIEDONB_03185	1.03e-66	-	-	-	-	-	-	-	-
HCIEDONB_03186	4.57e-217	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HCIEDONB_03187	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCIEDONB_03188	3.82e-139	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCIEDONB_03189	1.21e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases C terminal
HCIEDONB_03190	1.36e-220	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HCIEDONB_03191	1.63e-239	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases C terminal
HCIEDONB_03192	1.5e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
HCIEDONB_03193	4.91e-30	-	-	-	-	-	-	-	-
HCIEDONB_03194	5.25e-95	-	-	-	S	-	-	-	protein conserved in bacteria
HCIEDONB_03195	1.66e-304	-	-	-	L	-	-	-	Transposase DDE domain group 1
HCIEDONB_03196	9.71e-294	mtlA	2.7.1.197	-	G	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HCIEDONB_03197	1.02e-202	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCIEDONB_03198	1.78e-171	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	Mannitol dehydrogenase Rossmann domain
HCIEDONB_03199	1.18e-296	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HCIEDONB_03200	9.36e-143	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HCIEDONB_03201	6.35e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HCIEDONB_03202	7.37e-316	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HCIEDONB_03203	1.42e-247	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
HCIEDONB_03204	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_03205	1.13e-170	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HCIEDONB_03206	1.67e-222	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HCIEDONB_03207	1.22e-305	-	-	-	G	ko:K03535	-	ko00000,ko02000	Major Facilitator Superfamily
HCIEDONB_03208	1.62e-134	-	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HCIEDONB_03209	5.18e-122	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HCIEDONB_03210	4.58e-109	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HCIEDONB_03211	1.09e-292	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
HCIEDONB_03212	1.67e-222	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HCIEDONB_03213	3.49e-127	-	-	-	C	-	-	-	Nitroreductase family
HCIEDONB_03214	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HCIEDONB_03215	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HCIEDONB_03216	0.0	lysP	-	-	E	ko:K11733	-	ko00000,ko02000	amino acid
HCIEDONB_03218	1.08e-126	-	-	-	K	-	-	-	Cupin domain
HCIEDONB_03219	5.13e-268	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCIEDONB_03220	1.43e-179	potB	-	-	E	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1176 ABC-type spermidine putrescine transport system, permease component I
HCIEDONB_03221	7.93e-179	potC	-	-	E	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1177 ABC-type spermidine putrescine transport system, permease component II
HCIEDONB_03222	1.84e-261	potD	-	-	E	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0687 Spermidine putrescine-binding periplasmic protein
HCIEDONB_03224	0.0	-	-	-	H	-	-	-	HemY protein
HCIEDONB_03225	0.0	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HCIEDONB_03226	6.36e-171	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HCIEDONB_03227	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HCIEDONB_03228	4.16e-176	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HCIEDONB_03229	2.71e-280	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_03230	0.0	-	2.6.1.55	-	H	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	ko00000,ko00001,ko01000	Aminotransferase class-III
HCIEDONB_03231	4.96e-270	-	-	-	C	ko:K19954	-	ko00000,ko01000	alcohol dehydrogenase
HCIEDONB_03232	3.81e-294	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HCIEDONB_03233	0.0	pucI	-	-	FH	ko:K03457	-	ko00000	COG1953 Cytosine uracil thiamine allantoin permeases
HCIEDONB_03234	0.0	gltD	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HCIEDONB_03235	2.83e-300	preA	1.3.1.1	-	CF	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	dihydroorotate dehydrogenase
HCIEDONB_03236	0.0	hydA	3.5.2.2	-	F	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Amidohydrolase family
HCIEDONB_03238	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
HCIEDONB_03240	7.49e-282	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HCIEDONB_03241	1.15e-299	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HCIEDONB_03242	0.0	citS	2.7.13.3	-	T	ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HCIEDONB_03243	3.03e-158	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HCIEDONB_03244	1.07e-301	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HCIEDONB_03245	1.83e-234	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HCIEDONB_03247	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HCIEDONB_03249	3.68e-41	-	-	-	-	-	-	-	-
HCIEDONB_03252	3.6e-42	ydcG	-	-	K	ko:K07729	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HCIEDONB_03253	1.55e-129	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HCIEDONB_03254	3.29e-191	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCIEDONB_03255	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCIEDONB_03256	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HCIEDONB_03257	1.05e-277	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCIEDONB_03258	5.87e-156	-	-	-	K	ko:K10914,ko:K21828	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HCIEDONB_03261	1.24e-170	-	-	-	D	ko:K07322	-	ko00000	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HCIEDONB_03262	5.24e-124	-	-	-	S	-	-	-	Belongs to the UPF0312 family
HCIEDONB_03263	3.25e-274	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HCIEDONB_03266	1.93e-243	cnpD2	-	-	T	-	-	-	HD domain
HCIEDONB_03268	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HCIEDONB_03270	0.0	ydaO	-	-	E	-	-	-	amino acid
HCIEDONB_03271	3.25e-188	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCIEDONB_03272	1.83e-33	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HCIEDONB_03273	2.74e-223	ydbI	-	-	S	-	-	-	AI-2E family transporter
HCIEDONB_03274	9.76e-172	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HCIEDONB_03276	2.08e-176	glnH	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HCIEDONB_03277	1.04e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCIEDONB_03278	1.53e-151	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCIEDONB_03279	3.63e-91	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HCIEDONB_03280	4.99e-252	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HCIEDONB_03281	4.18e-71	yodB	-	-	K	-	-	-	transcriptional
HCIEDONB_03282	4.02e-299	-	-	-	S	-	-	-	SNARE associated Golgi protein
HCIEDONB_03283	3.32e-135	yngC	-	-	S	-	-	-	membrane-associated protein
HCIEDONB_03284	1.23e-208	msrR	-	-	K	-	-	-	COG1316 Transcriptional regulator
HCIEDONB_03286	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HCIEDONB_03287	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HCIEDONB_03288	1.03e-21	csbD	-	-	S	-	-	-	Belongs to the UPF0337 (CsbD) family
HCIEDONB_03289	1.62e-115	-	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	ComK protein
HCIEDONB_03290	6.99e-136	-	2.7.7.6	-	K	ko:K00960	-	ko00000,ko01000	Belongs to the sigma-70 factor family. ECF subfamily
HCIEDONB_03291	1.99e-194	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HCIEDONB_03292	2.06e-154	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HCIEDONB_03293	6.23e-149	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HCIEDONB_03294	8.34e-179	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HCIEDONB_03295	1.22e-191	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HCIEDONB_03296	3.2e-23	cpsE	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HCIEDONB_03297	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
HCIEDONB_03298	1.95e-79	cpsE	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HCIEDONB_03299	7.34e-43	-	-	-	S	-	-	-	Membrane protein involved in the export of O-antigen and teichoic acid
HCIEDONB_03300	2.11e-45	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
HCIEDONB_03302	8.48e-44	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HCIEDONB_03303	2.49e-33	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HCIEDONB_03304	8.15e-42	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HCIEDONB_03305	3.09e-240	-	2.7.7.13	-	G	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
HCIEDONB_03306	1.14e-295	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCIEDONB_03307	1.42e-115	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCIEDONB_03308	7.68e-135	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCIEDONB_03309	1.13e-283	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
HCIEDONB_03310	2.23e-70	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HCIEDONB_03312	7.11e-159	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HCIEDONB_03313	6.47e-23	-	3.2.2.24	-	O	ko:K05521	-	ko00000,ko01000	ADP-ribosylglycohydrolase
HCIEDONB_03314	1.29e-97	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HCIEDONB_03315	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HCIEDONB_03316	0.0	-	-	-	M	ko:K20276	ko02024,map02024	ko00000,ko00001	Non-essential cell division protein that could be required for efficient cell constriction
HCIEDONB_03317	1.68e-78	-	-	-	S	-	-	-	Helix-turn-helix
HCIEDONB_03318	2.69e-22	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HCIEDONB_03319	5.78e-268	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_03320	1.21e-121	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCIEDONB_03321	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCIEDONB_03322	1.82e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HCIEDONB_03323	7.07e-44	yodI	-	-	-	-	-	-	-
HCIEDONB_03324	7.51e-194	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HCIEDONB_03325	3.84e-171	yodH	-	-	Q	-	-	-	Methyltransferase
HCIEDONB_03326	2.23e-155	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HCIEDONB_03327	1.88e-89	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	N-4 methylation of cytosine
HCIEDONB_03328	4.1e-137	-	-	-	S	-	-	-	Protein of unknown function DUF262
HCIEDONB_03329	2.63e-51	-	-	-	-	-	-	-	-
HCIEDONB_03330	1.32e-67	-	-	-	L	-	-	-	Transposase
HCIEDONB_03331	3.38e-89	agaF	2.7.1.191	-	G	ko:K02744,ko:K02793	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HCIEDONB_03332	1.01e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HCIEDONB_03333	6.56e-182	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HCIEDONB_03334	2.81e-106	-	2.7.1.191	-	G	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HCIEDONB_03335	3.04e-171	-	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCIEDONB_03336	1.28e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HCIEDONB_03337	4.47e-126	-	-	-	K	-	-	-	Cupin domain
HCIEDONB_03338	0.0	-	3.5.2.14	-	EQ	ko:K01473	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit
HCIEDONB_03339	0.0	-	3.5.2.14	-	EQ	ko:K01474	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit
HCIEDONB_03340	0.0	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
HCIEDONB_03341	0.0	-	-	-	K	ko:K19505	-	ko00000,ko03000	PTS system fructose IIA component
HCIEDONB_03342	5.36e-97	-	2.7.1.191	-	G	ko:K02793,ko:K19506	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HCIEDONB_03343	8.95e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
HCIEDONB_03344	1.59e-173	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HCIEDONB_03345	1.61e-183	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PFAM Phosphotransferase system, mannose fructose sorbose family IID component
HCIEDONB_03346	2.67e-251	-	-	-	M	-	-	-	SIS domain
HCIEDONB_03347	3.28e-197	-	-	-	G	-	-	-	antiterminator
HCIEDONB_03348	2.47e-19	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCIEDONB_03349	2.45e-40	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	to PTS system galactitol-specific enzyme IIB component
HCIEDONB_03350	4.08e-251	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HCIEDONB_03352	3.75e-76	-	2.7.1.56	-	F	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HCIEDONB_03353	3.89e-109	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
HCIEDONB_03354	0.0	-	-	-	K	-	-	-	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HCIEDONB_03355	2.36e-270	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
HCIEDONB_03356	0.0	-	-	-	EQ	-	-	-	Hydantoinase oxoprolinase
HCIEDONB_03357	1.74e-291	-	-	-	F	ko:K10974	-	ko00000,ko02000	cytosine purines uracil thiamine allantoin
HCIEDONB_03358	1.92e-262	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
HCIEDONB_03359	0.0	apc3	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase
HCIEDONB_03360	4.48e-231	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HCIEDONB_03361	1.13e-89	-	-	-	S	-	-	-	YjbR
HCIEDONB_03362	1.52e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HCIEDONB_03363	1e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HCIEDONB_03364	0.0	-	-	-	L	-	-	-	Metallo-beta-lactamase superfamily
HCIEDONB_03365	1.37e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF3006)
HCIEDONB_03366	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HCIEDONB_03367	7.86e-242	csd1	-	-	S	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein, Csd1 family
HCIEDONB_03368	3.27e-27	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
HCIEDONB_03369	0.0	ybeC	-	-	E	-	-	-	amino acid
HCIEDONB_03371	0.0	-	-	-	O	-	-	-	cellulase activity
HCIEDONB_03372	1.18e-228	-	-	-	K	-	-	-	cell envelope-related transcriptional attenuator
HCIEDONB_03373	4.78e-79	-	-	-	-	-	-	-	-
HCIEDONB_03375	3.95e-223	ydhF	-	-	S	-	-	-	Oxidoreductase
HCIEDONB_03376	5.23e-192	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_03377	6.16e-13	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_03378	9.87e-70	-	-	-	S	-	-	-	Domain of unknown function (DUF3870)
HCIEDONB_03379	1.56e-299	-	1.3.99.32	-	I	ko:K16173	ko00362,ko01120,map00362,map01120	ko00000,ko00001,ko01000	Acyl-CoA dehydrogenase, N-terminal domain
HCIEDONB_03380	2.44e-286	-	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	acyl-CoA transferases carnitine dehydratase
HCIEDONB_03381	2.17e-243	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HCIEDONB_03382	2.67e-273	-	-	-	EGP	-	-	-	Major facilitator superfamily
HCIEDONB_03383	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
HCIEDONB_03384	2.39e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCIEDONB_03385	1.29e-66	ptcA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS cellobiose transporter subunit IIA
HCIEDONB_03386	2.15e-262	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HCIEDONB_03387	1.39e-296	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIEDONB_03388	1.9e-127	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	MFS/sugar transport protein
HCIEDONB_03389	2.07e-264	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_03390	7.73e-22	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HCIEDONB_03391	1.55e-94	ywoH	-	-	K	-	-	-	transcriptional
HCIEDONB_03392	1.22e-269	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HCIEDONB_03393	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
HCIEDONB_03394	7.06e-224	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HCIEDONB_03395	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HCIEDONB_03397	1.16e-141	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HCIEDONB_03398	3.92e-217	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCIEDONB_03399	1.02e-147	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HCIEDONB_03400	4.75e-267	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HCIEDONB_03401	3.4e-126	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HCIEDONB_03402	6.56e-131	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HCIEDONB_03403	3.8e-58	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEDONB_03404	2.22e-118	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEDONB_03405	3.83e-22	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HCIEDONB_03406	1.36e-266	-	-	-	L	ko:K07496	-	ko00000	Transposase
HCIEDONB_03407	3.96e-36	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEDONB_03408	2.94e-60	-	-	-	-	-	-	-	-
HCIEDONB_03409	6.55e-142	yjlB	-	-	S	-	-	-	Cupin domain
HCIEDONB_03410	4.15e-192	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
HCIEDONB_03411	1.06e-173	glx2	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HCIEDONB_03412	2.39e-223	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HCIEDONB_03413	5.57e-126	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HCIEDONB_03414	0.0	comM	-	-	O	ko:K07391	-	ko00000	Mg chelatase subunit ChlI
HCIEDONB_03415	1.69e-197	-	-	-	S	-	-	-	transposase or invertase
HCIEDONB_03416	3.69e-30	-	-	-	-	-	-	-	-
HCIEDONB_03417	4.5e-259	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HCIEDONB_03418	1.81e-316	xylT	-	-	U	ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HCIEDONB_03419	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HCIEDONB_03420	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HCIEDONB_03421	9.1e-281	xylR	-	-	GK	-	-	-	ROK family
HCIEDONB_03422	2.75e-267	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HCIEDONB_03423	2.24e-202	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HCIEDONB_03424	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HCIEDONB_03425	5.05e-259	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HCIEDONB_03426	1.39e-124	-	-	-	S	-	-	-	NYN domain
HCIEDONB_03427	1.06e-185	fnt	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HCIEDONB_03428	2.48e-55	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HCIEDONB_03429	1e-292	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HCIEDONB_03430	1.01e-180	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
HCIEDONB_03431	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCIEDONB_03432	5.36e-120	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HCIEDONB_03433	8.2e-210	XK27_10120	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HCIEDONB_03434	7.08e-156	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HCIEDONB_03435	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HCIEDONB_03436	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCIEDONB_03437	1.63e-278	adhB	1.1.1.1, 1.1.1.202	-	C	ko:K00001,ko:K00086	ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HCIEDONB_03438	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
HCIEDONB_03439	2.42e-69	xylS	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HCIEDONB_03440	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2339)
HCIEDONB_03441	3.62e-291	-	-	-	I	-	-	-	Acyl-CoA dehydrogenase, N-terminal domain
HCIEDONB_03442	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HCIEDONB_03443	2.1e-247	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HCIEDONB_03444	5.4e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HCIEDONB_03445	7.61e-173	phnE	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCIEDONB_03446	1.05e-183	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCIEDONB_03447	0.0	-	-	-	L	-	-	-	RNA-directed DNA polymerase (reverse transcriptase)
HCIEDONB_03448	8.61e-223	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HCIEDONB_03449	0.0	yfkN_2	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HCIEDONB_03450	5.3e-264	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HCIEDONB_03452	8.02e-59	-	-	-	-	-	-	-	-
HCIEDONB_03453	9.61e-172	-	-	-	T	-	-	-	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HCIEDONB_03454	2.86e-57	-	-	-	-	-	-	-	-
HCIEDONB_03456	9.7e-69	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
HCIEDONB_03457	2.74e-24	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
HCIEDONB_03458	1.18e-170	-	-	-	T	-	-	-	Histidine kinase
HCIEDONB_03459	9.79e-168	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HCIEDONB_03461	4.24e-216	-	3.5.1.4	-	C	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Acetamidase
HCIEDONB_03462	9.45e-315	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
HCIEDONB_03463	1.43e-30	-	-	-	S	-	-	-	Zinc-ribbon containing domain
HCIEDONB_03464	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HCIEDONB_03465	2.66e-157	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HCIEDONB_03466	2.84e-287	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCIEDONB_03467	6.79e-79	-	-	-	-	-	-	-	-
HCIEDONB_03468	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4277)
HCIEDONB_03471	7.6e-216	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HCIEDONB_03472	9.81e-279	-	-	-	EGP	-	-	-	Major facilitator superfamily
HCIEDONB_03473	1.82e-254	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HCIEDONB_03474	3.26e-23	-	-	-	S	-	-	-	YvrJ protein family
HCIEDONB_03475	8.05e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HCIEDONB_03476	2.97e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF1659)
HCIEDONB_03477	0.0	wprA	-	-	O	ko:K13274,ko:K20276	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HCIEDONB_03478	1.16e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HCIEDONB_03479	1.19e-66	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCIEDONB_03480	2.83e-69	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HCIEDONB_03481	1.58e-106	-	-	-	-	-	-	-	-
HCIEDONB_03482	9.22e-317	celD	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIEDONB_03483	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HCIEDONB_03484	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
HCIEDONB_03485	5.7e-199	kdsA	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the KdsA family
HCIEDONB_03486	2.04e-226	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the SIS family. GutQ KpsF subfamily
HCIEDONB_03487	1.26e-211	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCIEDONB_03488	1.34e-09	-	-	-	S	-	-	-	ABC-2 family transporter protein
HCIEDONB_03489	1.95e-293	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HCIEDONB_03490	3.84e-278	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HCIEDONB_03492	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
HCIEDONB_03493	5.43e-190	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCIEDONB_03494	4.5e-279	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCIEDONB_03495	6.14e-298	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCIEDONB_03496	4.26e-169	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HCIEDONB_03497	1.77e-178	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HCIEDONB_03498	2.27e-69	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HCIEDONB_03499	2.06e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HCIEDONB_03500	1.85e-205	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCIEDONB_03501	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HCIEDONB_03502	0.0	-	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HCIEDONB_03503	3.93e-114	-	-	-	-	-	-	-	-
HCIEDONB_03504	1.23e-188	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HCIEDONB_03505	4.8e-170	ycdF	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Short-chain dehydrogenase reductase sdr
HCIEDONB_03506	2.31e-44	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HCIEDONB_03507	5.74e-142	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HCIEDONB_03508	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HCIEDONB_03509	9.13e-210	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HCIEDONB_03510	3.57e-158	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HCIEDONB_03511	7.87e-213	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HCIEDONB_03512	3.03e-38	-	-	-	-	-	-	-	-
HCIEDONB_03513	0.0	ppc	4.1.1.31	-	C	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HCIEDONB_03514	3.52e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCIEDONB_03515	2.23e-155	yabE	-	-	S	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	3D domain
HCIEDONB_03517	1.56e-127	-	-	-	KT	-	-	-	HD domain
HCIEDONB_03518	0.0	pip	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HCIEDONB_03519	1.23e-63	yqgV	-	-	S	-	-	-	Thiamine-binding protein
HCIEDONB_03520	1.56e-254	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HCIEDONB_03521	0.0	-	-	-	S	-	-	-	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HCIEDONB_03522	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
HCIEDONB_03523	1.41e-109	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HCIEDONB_03524	9.73e-228	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
HCIEDONB_03525	3.45e-174	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HCIEDONB_03526	1.04e-217	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HCIEDONB_03527	2.74e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)