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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MCKBDDEF_00001	9.06e-78	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MCKBDDEF_00002	3.15e-108	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MCKBDDEF_00003	3.15e-99	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MCKBDDEF_00004	4.77e-73	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MCKBDDEF_00005	1.41e-68	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MCKBDDEF_00006	2.8e-313	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MCKBDDEF_00007	9.96e-213	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MCKBDDEF_00008	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
MCKBDDEF_00009	5.44e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MCKBDDEF_00010	1.3e-99	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
MCKBDDEF_00011	7.06e-143	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MCKBDDEF_00012	3.34e-80	yqfX	-	-	S	-	-	-	membrane
MCKBDDEF_00013	1.97e-256	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MCKBDDEF_00014	8.76e-63	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
MCKBDDEF_00015	1.08e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MCKBDDEF_00016	1.12e-98	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MCKBDDEF_00017	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MCKBDDEF_00018	5.56e-288	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MCKBDDEF_00019	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MCKBDDEF_00020	2.72e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MCKBDDEF_00021	1.75e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MCKBDDEF_00022	5.88e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MCKBDDEF_00023	5.62e-184	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MCKBDDEF_00024	5.46e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MCKBDDEF_00025	2.5e-99	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MCKBDDEF_00026	3.42e-68	yqzD	-	-	-	-	-	-	-
MCKBDDEF_00027	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MCKBDDEF_00028	8.62e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MCKBDDEF_00029	5.38e-11	yqgO	-	-	-	-	-	-	-
MCKBDDEF_00030	3.61e-276	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MCKBDDEF_00031	9.1e-39	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
MCKBDDEF_00032	7.14e-229	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MCKBDDEF_00033	4.66e-280	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
MCKBDDEF_00034	8.94e-255	yqgU	-	-	-	-	-	-	-
MCKBDDEF_00035	2.99e-65	dglA	-	-	S	-	-	-	Thiamine-binding protein
MCKBDDEF_00036	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
MCKBDDEF_00037	3.45e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MCKBDDEF_00038	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MCKBDDEF_00039	1.91e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
MCKBDDEF_00041	8.33e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MCKBDDEF_00042	6.23e-303	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MCKBDDEF_00043	2.62e-238	yqxL	-	-	P	-	-	-	Mg2 transporter protein
MCKBDDEF_00044	3.84e-258	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MCKBDDEF_00045	9.79e-235	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MCKBDDEF_00046	4.46e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MCKBDDEF_00047	2.27e-93	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
MCKBDDEF_00048	3.14e-26	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
MCKBDDEF_00049	2.66e-99	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MCKBDDEF_00050	2.62e-78	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
MCKBDDEF_00051	8.16e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
MCKBDDEF_00052	2.8e-70	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MCKBDDEF_00053	1.28e-153	yqxM	-	-	-	ko:K19433	-	ko00000	-
MCKBDDEF_00054	3.13e-101	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MCKBDDEF_00055	1.82e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
MCKBDDEF_00056	2.75e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
MCKBDDEF_00057	2.71e-31	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
MCKBDDEF_00058	8.78e-195	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MCKBDDEF_00059	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MCKBDDEF_00060	4.04e-265	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MCKBDDEF_00061	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MCKBDDEF_00062	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MCKBDDEF_00063	3.18e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MCKBDDEF_00064	1.58e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MCKBDDEF_00065	5.64e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MCKBDDEF_00066	7e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MCKBDDEF_00067	7.65e-83	yqhP	-	-	-	-	-	-	-
MCKBDDEF_00068	7.33e-221	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
MCKBDDEF_00069	9.4e-117	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MCKBDDEF_00070	2.11e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MCKBDDEF_00071	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MCKBDDEF_00072	9.89e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MCKBDDEF_00073	1.27e-220	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MCKBDDEF_00074	6.93e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MCKBDDEF_00075	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MCKBDDEF_00076	3.72e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MCKBDDEF_00077	5.23e-261	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MCKBDDEF_00078	4.27e-130	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MCKBDDEF_00079	2.35e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MCKBDDEF_00080	2.74e-94	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MCKBDDEF_00081	4.67e-86	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MCKBDDEF_00082	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MCKBDDEF_00083	1.36e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_00084	2.2e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MCKBDDEF_00085	8.75e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MCKBDDEF_00086	8.28e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCKBDDEF_00087	2.67e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCKBDDEF_00088	9.49e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MCKBDDEF_00089	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MCKBDDEF_00090	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MCKBDDEF_00091	4.38e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MCKBDDEF_00092	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MCKBDDEF_00093	8.85e-304	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MCKBDDEF_00094	6.11e-187	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MCKBDDEF_00095	2.48e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MCKBDDEF_00098	2.28e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MCKBDDEF_00100	1.15e-145	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
MCKBDDEF_00101	1.96e-131	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MCKBDDEF_00103	1.39e-136	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
MCKBDDEF_00104	1.1e-174	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MCKBDDEF_00105	2.78e-272	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MCKBDDEF_00106	4.16e-198	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MCKBDDEF_00107	2.06e-259	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MCKBDDEF_00108	2.52e-263	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MCKBDDEF_00109	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MCKBDDEF_00110	2.32e-204	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MCKBDDEF_00111	6.25e-47	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MCKBDDEF_00112	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MCKBDDEF_00113	1.67e-195	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
MCKBDDEF_00114	2.61e-260	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MCKBDDEF_00115	3.45e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
MCKBDDEF_00116	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MCKBDDEF_00117	4.56e-221	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MCKBDDEF_00118	9.83e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MCKBDDEF_00119	1.78e-284	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MCKBDDEF_00120	4.77e-216	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MCKBDDEF_00121	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MCKBDDEF_00122	3.23e-172	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MCKBDDEF_00123	4.25e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MCKBDDEF_00124	2.89e-163	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MCKBDDEF_00125	4.58e-219	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MCKBDDEF_00126	3.45e-85	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_00128	1.33e-95	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MCKBDDEF_00129	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MCKBDDEF_00130	1.06e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MCKBDDEF_00131	1.68e-190	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MCKBDDEF_00132	1.3e-34	yqzJ	-	-	-	-	-	-	-
MCKBDDEF_00133	1.92e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MCKBDDEF_00134	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MCKBDDEF_00135	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MCKBDDEF_00136	3.37e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MCKBDDEF_00137	1.29e-188	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MCKBDDEF_00138	7.32e-247	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MCKBDDEF_00139	6.43e-66	-	-	-	S	-	-	-	GlpM protein
MCKBDDEF_00140	1.42e-196	-	-	-	K	-	-	-	LysR substrate binding domain
MCKBDDEF_00141	4.32e-122	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MCKBDDEF_00142	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MCKBDDEF_00145	1.85e-312	-	6.1.3.1, 6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MCKBDDEF_00146	7.97e-168	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MCKBDDEF_00147	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00148	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00149	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00150	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00151	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00152	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00153	0.0	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MCKBDDEF_00154	1.9e-279	-	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MCKBDDEF_00155	5.31e-304	-	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MCKBDDEF_00156	1.38e-174	-	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MCKBDDEF_00157	1.95e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MCKBDDEF_00158	6.83e-224	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MCKBDDEF_00159	2.39e-180	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MCKBDDEF_00160	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MCKBDDEF_00161	2.58e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MCKBDDEF_00162	7.67e-96	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCKBDDEF_00164	2.91e-238	yueF	-	-	S	-	-	-	transporter activity
MCKBDDEF_00166	9.19e-76	-	-	-	S	-	-	-	YolD-like protein
MCKBDDEF_00167	7.74e-298	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MCKBDDEF_00168	4.67e-114	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MCKBDDEF_00169	1.71e-80	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
MCKBDDEF_00170	1.76e-224	yqkA	-	-	K	-	-	-	GrpB protein
MCKBDDEF_00171	2.2e-79	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
MCKBDDEF_00172	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
MCKBDDEF_00173	2.27e-223	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MCKBDDEF_00174	1.45e-11	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
MCKBDDEF_00175	1.08e-216	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MCKBDDEF_00176	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
MCKBDDEF_00177	1.04e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MCKBDDEF_00178	6.89e-279	yqxK	-	-	L	-	-	-	DNA helicase
MCKBDDEF_00179	1.34e-74	ansR	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_00180	1.3e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
MCKBDDEF_00181	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MCKBDDEF_00182	2.4e-311	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MCKBDDEF_00183	4.12e-310	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MCKBDDEF_00184	3.39e-31	-	-	-	-	-	-	-	-
MCKBDDEF_00185	7.07e-40	yqkK	-	-	-	-	-	-	-
MCKBDDEF_00186	3.53e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MCKBDDEF_00187	4.56e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MCKBDDEF_00188	9.51e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
MCKBDDEF_00189	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MCKBDDEF_00190	4.97e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MCKBDDEF_00191	1.1e-192	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MCKBDDEF_00192	1.43e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MCKBDDEF_00193	4.86e-77	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MCKBDDEF_00194	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MCKBDDEF_00195	7.94e-173	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCKBDDEF_00196	3.86e-142	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
MCKBDDEF_00197	2.85e-103	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MCKBDDEF_00198	8.19e-244	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MCKBDDEF_00199	1.51e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MCKBDDEF_00200	5.32e-142	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MCKBDDEF_00201	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MCKBDDEF_00202	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MCKBDDEF_00203	2.11e-197	ypuA	-	-	S	-	-	-	Secreted protein
MCKBDDEF_00204	4.12e-104	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MCKBDDEF_00205	1.42e-107	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
MCKBDDEF_00206	6.56e-131	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MCKBDDEF_00207	4.92e-71	ypuD	-	-	-	-	-	-	-
MCKBDDEF_00208	1.08e-267	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MCKBDDEF_00209	3.97e-144	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MCKBDDEF_00210	1.8e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MCKBDDEF_00211	6.92e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MCKBDDEF_00212	2.74e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCKBDDEF_00213	4.51e-118	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MCKBDDEF_00215	2.09e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MCKBDDEF_00216	2.73e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MCKBDDEF_00217	6.14e-122	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
MCKBDDEF_00218	1.62e-275	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MCKBDDEF_00219	3.75e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MCKBDDEF_00220	8.99e-116	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MCKBDDEF_00221	1.49e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MCKBDDEF_00222	4.31e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MCKBDDEF_00223	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MCKBDDEF_00224	4.39e-252	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MCKBDDEF_00225	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_00226	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_00227	3.22e-135	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MCKBDDEF_00228	5.62e-254	rsiX	-	-	-	-	-	-	-
MCKBDDEF_00229	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCKBDDEF_00230	2.16e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MCKBDDEF_00231	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MCKBDDEF_00232	7.41e-254	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MCKBDDEF_00233	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MCKBDDEF_00234	1.09e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MCKBDDEF_00235	1.5e-132	ypbE	-	-	M	-	-	-	Lysin motif
MCKBDDEF_00236	1.92e-111	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
MCKBDDEF_00237	1.15e-189	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MCKBDDEF_00238	3.35e-137	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MCKBDDEF_00239	1.81e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MCKBDDEF_00240	1.85e-239	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MCKBDDEF_00241	7.48e-155	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MCKBDDEF_00242	1.92e-204	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MCKBDDEF_00243	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MCKBDDEF_00244	3.83e-76	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
MCKBDDEF_00245	7.86e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
MCKBDDEF_00246	5.8e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MCKBDDEF_00247	5.73e-264	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MCKBDDEF_00248	1.98e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MCKBDDEF_00249	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
MCKBDDEF_00250	6.19e-136	yphA	-	-	-	-	-	-	-
MCKBDDEF_00251	9.53e-317	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MCKBDDEF_00252	4.93e-244	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MCKBDDEF_00253	3.25e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MCKBDDEF_00254	3.4e-173	yphF	-	-	-	-	-	-	-
MCKBDDEF_00255	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MCKBDDEF_00256	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MCKBDDEF_00257	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MCKBDDEF_00258	6.23e-47	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MCKBDDEF_00259	3.96e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MCKBDDEF_00260	7.76e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MCKBDDEF_00261	2.29e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MCKBDDEF_00262	8.53e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MCKBDDEF_00263	3.54e-181	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MCKBDDEF_00264	9.75e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MCKBDDEF_00265	7.47e-259	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MCKBDDEF_00266	2.93e-79	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MCKBDDEF_00267	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MCKBDDEF_00268	2.37e-211	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MCKBDDEF_00269	2.46e-169	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MCKBDDEF_00270	2.05e-147	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
MCKBDDEF_00271	1.42e-289	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MCKBDDEF_00272	7.71e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MCKBDDEF_00273	7.15e-256	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MCKBDDEF_00274	1.24e-260	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MCKBDDEF_00275	3.46e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MCKBDDEF_00276	1.76e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MCKBDDEF_00277	2.6e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MCKBDDEF_00278	3.34e-101	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MCKBDDEF_00279	2.86e-127	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MCKBDDEF_00280	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MCKBDDEF_00281	4.02e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MCKBDDEF_00282	7.24e-134	ypjA	-	-	S	-	-	-	membrane
MCKBDDEF_00283	2.05e-182	ypjB	-	-	S	-	-	-	sporulation protein
MCKBDDEF_00284	1.97e-55	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MCKBDDEF_00285	5.09e-212	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MCKBDDEF_00286	4.31e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MCKBDDEF_00287	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MCKBDDEF_00288	3.98e-188	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MCKBDDEF_00289	6.19e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MCKBDDEF_00290	7.44e-169	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MCKBDDEF_00291	2.98e-268	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MCKBDDEF_00292	3.99e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MCKBDDEF_00293	7.73e-231	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MCKBDDEF_00294	1.14e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MCKBDDEF_00295	1.99e-202	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MCKBDDEF_00296	2.41e-84	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MCKBDDEF_00297	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MCKBDDEF_00298	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MCKBDDEF_00299	2.27e-103	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_00300	1.46e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MCKBDDEF_00301	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MCKBDDEF_00302	3.42e-167	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MCKBDDEF_00303	1.02e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MCKBDDEF_00304	1.04e-118	ypoC	-	-	-	-	-	-	-
MCKBDDEF_00305	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MCKBDDEF_00306	8.84e-146	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MCKBDDEF_00307	4.72e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MCKBDDEF_00308	0.000542	-	-	-	-	ko:K06430	-	ko00000	-
MCKBDDEF_00312	1.85e-74	yppG	-	-	S	-	-	-	YppG-like protein
MCKBDDEF_00313	1.85e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MCKBDDEF_00314	1.21e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MCKBDDEF_00315	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MCKBDDEF_00316	1.99e-302	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MCKBDDEF_00318	9.36e-48	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
MCKBDDEF_00319	1.33e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MCKBDDEF_00320	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MCKBDDEF_00321	5.46e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MCKBDDEF_00322	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
MCKBDDEF_00324	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
MCKBDDEF_00325	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MCKBDDEF_00326	4.72e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MCKBDDEF_00327	2.4e-296	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
MCKBDDEF_00328	1.05e-05	-	-	-	-	-	-	-	-
MCKBDDEF_00329	3.79e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
MCKBDDEF_00330	1.21e-08	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MCKBDDEF_00331	3.81e-67	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
MCKBDDEF_00332	2.52e-136	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MCKBDDEF_00333	5.13e-268	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MCKBDDEF_00334	2.09e-116	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MCKBDDEF_00335	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MCKBDDEF_00336	8.23e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
MCKBDDEF_00337	2.44e-10	-	-	-	-	-	-	-	-
MCKBDDEF_00338	3.33e-210	ypcP	-	-	L	-	-	-	5'3' exonuclease
MCKBDDEF_00340	7.37e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
MCKBDDEF_00341	2.79e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MCKBDDEF_00342	2.06e-159	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
MCKBDDEF_00343	6.59e-40	ypeQ	-	-	S	-	-	-	Zinc-finger
MCKBDDEF_00344	9.27e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MCKBDDEF_00345	5.19e-17	degR	-	-	-	-	-	-	-
MCKBDDEF_00346	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MCKBDDEF_00347	1.49e-274	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MCKBDDEF_00348	2.3e-227	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MCKBDDEF_00349	9.26e-112	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MCKBDDEF_00350	7.66e-127	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MCKBDDEF_00351	5.44e-202	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MCKBDDEF_00352	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MCKBDDEF_00353	4.8e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MCKBDDEF_00354	8.22e-171	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
MCKBDDEF_00355	6.48e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
MCKBDDEF_00356	6.22e-204	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MCKBDDEF_00357	6.07e-117	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MCKBDDEF_00358	1.35e-147	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MCKBDDEF_00359	1.5e-142	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MCKBDDEF_00360	5.8e-224	yplP	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_00361	1.42e-307	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MCKBDDEF_00362	8.98e-55	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
MCKBDDEF_00363	2.43e-135	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MCKBDDEF_00364	6.09e-175	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MCKBDDEF_00365	5.59e-126	ypmS	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_00366	3.35e-89	ypoP	-	-	K	-	-	-	transcriptional
MCKBDDEF_00367	2.82e-132	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MCKBDDEF_00368	4.61e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MCKBDDEF_00369	3.43e-134	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MCKBDDEF_00370	0.0	yokA	-	-	L	-	-	-	Recombinase
MCKBDDEF_00371	4.29e-109	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MCKBDDEF_00372	4.26e-109	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
MCKBDDEF_00373	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MCKBDDEF_00374	2.6e-66	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MCKBDDEF_00376	3.41e-216	-	-	-	S	-	-	-	amine dehydrogenase activity
MCKBDDEF_00378	6.38e-259	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MCKBDDEF_00379	1.24e-50	yoqH	-	-	M	-	-	-	LysM domain
MCKBDDEF_00384	4.14e-94	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MCKBDDEF_00385	6.87e-277	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
MCKBDDEF_00386	1.88e-223	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
MCKBDDEF_00387	3.12e-90	cgeA	-	-	-	ko:K06319	-	ko00000	-
MCKBDDEF_00388	1.64e-62	cgeC	-	-	-	ko:K06321	-	ko00000	-
MCKBDDEF_00389	8.84e-316	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
MCKBDDEF_00390	5.71e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
MCKBDDEF_00392	1.19e-83	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
MCKBDDEF_00393	1.69e-312	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MCKBDDEF_00394	1.19e-161	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MCKBDDEF_00395	4.64e-160	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MCKBDDEF_00396	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MCKBDDEF_00397	9.87e-204	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
MCKBDDEF_00398	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
MCKBDDEF_00399	8.13e-62	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
MCKBDDEF_00400	2.45e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MCKBDDEF_00401	1.9e-161	yodN	-	-	-	-	-	-	-
MCKBDDEF_00403	9.77e-34	yozD	-	-	S	-	-	-	YozD-like protein
MCKBDDEF_00404	5.88e-131	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MCKBDDEF_00405	1.16e-72	yodL	-	-	S	-	-	-	YodL-like
MCKBDDEF_00407	1.05e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MCKBDDEF_00408	7.76e-193	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MCKBDDEF_00409	6.87e-50	yodI	-	-	-	-	-	-	-
MCKBDDEF_00410	6.12e-166	yodH	-	-	Q	-	-	-	Methyltransferase
MCKBDDEF_00411	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MCKBDDEF_00412	5.86e-168	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_00413	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MCKBDDEF_00414	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
MCKBDDEF_00415	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MCKBDDEF_00416	1.97e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MCKBDDEF_00417	1.09e-221	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MCKBDDEF_00418	2.43e-140	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MCKBDDEF_00419	1.35e-138	yodC	-	-	C	-	-	-	nitroreductase
MCKBDDEF_00420	1.2e-74	yodB	-	-	K	-	-	-	transcriptional
MCKBDDEF_00421	2.74e-92	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
MCKBDDEF_00422	1.5e-88	iolK	-	-	S	-	-	-	tautomerase
MCKBDDEF_00424	4.87e-106	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
MCKBDDEF_00425	4.91e-209	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MCKBDDEF_00426	5.2e-31	-	-	-	-	-	-	-	-
MCKBDDEF_00427	8.09e-80	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MCKBDDEF_00428	1.57e-162	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MCKBDDEF_00429	1.68e-192	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MCKBDDEF_00430	2.39e-310	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
MCKBDDEF_00432	4.5e-142	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MCKBDDEF_00433	1.13e-276	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MCKBDDEF_00434	3.47e-287	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MCKBDDEF_00435	6.26e-143	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MCKBDDEF_00436	4.2e-209	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
MCKBDDEF_00437	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
MCKBDDEF_00438	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MCKBDDEF_00439	7.41e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MCKBDDEF_00440	1.98e-179	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MCKBDDEF_00441	2.82e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MCKBDDEF_00442	4.17e-298	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MCKBDDEF_00443	8.22e-213	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MCKBDDEF_00444	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
MCKBDDEF_00445	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MCKBDDEF_00446	1.11e-41	yozC	-	-	-	-	-	-	-
MCKBDDEF_00448	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
MCKBDDEF_00449	6.36e-50	yocN	-	-	-	-	-	-	-
MCKBDDEF_00450	1.87e-57	yozN	-	-	-	-	-	-	-
MCKBDDEF_00451	2.29e-116	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MCKBDDEF_00452	4.98e-13	yocN	-	-	-	-	-	-	-
MCKBDDEF_00453	2.71e-13	yocL	-	-	-	-	-	-	-
MCKBDDEF_00454	4.5e-79	yocK	-	-	T	-	-	-	general stress protein
MCKBDDEF_00456	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MCKBDDEF_00457	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MCKBDDEF_00458	9.79e-168	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
MCKBDDEF_00460	3.72e-238	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
MCKBDDEF_00461	2.27e-123	yocC	-	-	-	-	-	-	-
MCKBDDEF_00462	4.8e-179	-	-	-	J	-	-	-	Protein required for attachment to host cells
MCKBDDEF_00463	8.99e-116	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MCKBDDEF_00464	1.19e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MCKBDDEF_00465	6.33e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MCKBDDEF_00466	1.57e-118	yobW	-	-	-	-	-	-	-
MCKBDDEF_00467	1.98e-174	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MCKBDDEF_00468	8.84e-121	yobS	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_00469	9.78e-169	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MCKBDDEF_00470	1.05e-70	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
MCKBDDEF_00471	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MCKBDDEF_00472	3.25e-72	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MCKBDDEF_00473	5.5e-56	-	-	-	-	-	-	-	-
MCKBDDEF_00474	1.63e-128	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MCKBDDEF_00476	2.99e-22	yoaF	-	-	-	-	-	-	-
MCKBDDEF_00477	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MCKBDDEF_00478	4.74e-243	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCKBDDEF_00479	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MCKBDDEF_00480	1.1e-261	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MCKBDDEF_00481	2.12e-176	yoxB	-	-	-	-	-	-	-
MCKBDDEF_00482	3.03e-50	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MCKBDDEF_00483	1.73e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MCKBDDEF_00484	8.13e-82	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MCKBDDEF_00485	3.42e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MCKBDDEF_00486	2.82e-259	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MCKBDDEF_00487	7.8e-207	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_00488	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MCKBDDEF_00489	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MCKBDDEF_00490	1.77e-239	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MCKBDDEF_00491	2.6e-199	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_00492	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MCKBDDEF_00493	3.29e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
MCKBDDEF_00494	1.95e-255	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
MCKBDDEF_00495	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MCKBDDEF_00496	6.69e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MCKBDDEF_00497	3.97e-125	-	-	-	L	-	-	-	Integrase
MCKBDDEF_00499	2.13e-124	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
MCKBDDEF_00500	7.44e-312	yoeA	-	-	V	-	-	-	MATE efflux family protein
MCKBDDEF_00501	1.16e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MCKBDDEF_00502	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MCKBDDEF_00503	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_00504	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_00505	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_00506	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_00507	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
MCKBDDEF_00508	1.96e-84	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MCKBDDEF_00509	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MCKBDDEF_00510	1.79e-266	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MCKBDDEF_00511	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MCKBDDEF_00512	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MCKBDDEF_00513	2.77e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MCKBDDEF_00514	3.48e-214	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MCKBDDEF_00515	1.67e-176	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MCKBDDEF_00516	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MCKBDDEF_00517	5.33e-135	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MCKBDDEF_00518	3.16e-144	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MCKBDDEF_00519	2.26e-95	yngA	-	-	S	-	-	-	membrane
MCKBDDEF_00520	8.7e-184	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MCKBDDEF_00521	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MCKBDDEF_00522	3.25e-272	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MCKBDDEF_00523	7.45e-167	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MCKBDDEF_00524	1.12e-246	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MCKBDDEF_00525	3.74e-284	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MCKBDDEF_00526	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
MCKBDDEF_00527	8.91e-162	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MCKBDDEF_00528	7.47e-156	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MCKBDDEF_00529	1.18e-177	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MCKBDDEF_00530	6.75e-288	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MCKBDDEF_00531	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_00532	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_00533	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_00534	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MCKBDDEF_00535	8.84e-316	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
MCKBDDEF_00536	6.28e-163	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MCKBDDEF_00537	5.65e-311	-	-	-	T	-	-	-	Histidine kinase
MCKBDDEF_00538	1.43e-67	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
MCKBDDEF_00539	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
MCKBDDEF_00540	1.44e-270	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
MCKBDDEF_00542	4.6e-13	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
MCKBDDEF_00543	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
MCKBDDEF_00544	4.51e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
MCKBDDEF_00545	2e-199	yndG	-	-	S	-	-	-	DoxX-like family
MCKBDDEF_00546	1.07e-284	exuT	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	Sugar (and other) transporter
MCKBDDEF_00547	2.14e-232	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
MCKBDDEF_00548	5.86e-191	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MCKBDDEF_00549	3.96e-271	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
MCKBDDEF_00550	5.27e-147	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
MCKBDDEF_00551	1.26e-243	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MCKBDDEF_00552	1.15e-233	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MCKBDDEF_00553	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MCKBDDEF_00554	1.82e-63	ynfC	-	-	-	-	-	-	-
MCKBDDEF_00555	5.42e-20	-	-	-	-	-	-	-	-
MCKBDDEF_00556	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MCKBDDEF_00557	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MCKBDDEF_00558	9.94e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MCKBDDEF_00559	2.6e-120	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MCKBDDEF_00560	2.67e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MCKBDDEF_00561	7.79e-70	yneQ	-	-	-	-	-	-	-
MCKBDDEF_00562	2.94e-97	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MCKBDDEF_00563	1.73e-44	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
MCKBDDEF_00565	8.17e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MCKBDDEF_00566	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MCKBDDEF_00567	1.47e-20	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
MCKBDDEF_00568	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
MCKBDDEF_00569	7.01e-82	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
MCKBDDEF_00570	1.18e-98	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MCKBDDEF_00571	2.27e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MCKBDDEF_00572	7.09e-76	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MCKBDDEF_00573	3.14e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MCKBDDEF_00574	1.97e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MCKBDDEF_00575	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MCKBDDEF_00576	1.08e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MCKBDDEF_00577	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MCKBDDEF_00578	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
MCKBDDEF_00579	5.22e-145	yneB	-	-	L	-	-	-	resolvase
MCKBDDEF_00580	1.01e-67	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MCKBDDEF_00581	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MCKBDDEF_00583	3.2e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MCKBDDEF_00584	1.04e-183	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
MCKBDDEF_00585	1.74e-11	-	-	-	-	-	-	-	-
MCKBDDEF_00586	1.37e-182	yndL	-	-	S	-	-	-	Replication protein
MCKBDDEF_00587	6.07e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MCKBDDEF_00588	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
MCKBDDEF_00591	9.28e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MCKBDDEF_00592	3.33e-152	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
MCKBDDEF_00593	6.88e-257	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCKBDDEF_00594	4.55e-139	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MCKBDDEF_00595	3.28e-128	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MCKBDDEF_00596	1.64e-77	yoaP	-	-	K	-	-	-	YoaP-like
MCKBDDEF_00597	1.34e-94	yoaP	-	-	K	-	-	-	YoaP-like
MCKBDDEF_00599	2.75e-39	-	-	-	-	-	-	-	-
MCKBDDEF_00601	2.78e-24	-	-	-	-	-	-	-	-
MCKBDDEF_00602	3.63e-96	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
MCKBDDEF_00603	8.07e-235	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MCKBDDEF_00604	8.43e-73	dinB	-	-	S	-	-	-	DinB family
MCKBDDEF_00605	2.21e-27	-	-	-	-	-	-	-	-
MCKBDDEF_00609	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MCKBDDEF_00610	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
MCKBDDEF_00611	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MCKBDDEF_00612	9.04e-278	xylR	-	-	GK	-	-	-	ROK family
MCKBDDEF_00613	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MCKBDDEF_00614	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MCKBDDEF_00615	3.19e-265	mrjp	-	-	G	-	-	-	Major royal jelly protein
MCKBDDEF_00616	4.7e-51	-	-	-	T	-	-	-	Histidine kinase
MCKBDDEF_00617	2.1e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
MCKBDDEF_00621	4.5e-115	-	-	-	-	-	-	-	-
MCKBDDEF_00622	1.03e-28	-	-	-	-	-	-	-	-
MCKBDDEF_00623	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MCKBDDEF_00624	4.39e-88	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
MCKBDDEF_00625	1.01e-311	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MCKBDDEF_00626	2.7e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MCKBDDEF_00627	1.55e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MCKBDDEF_00628	1.86e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MCKBDDEF_00629	2.24e-141	ymaB	-	-	S	-	-	-	MutT family
MCKBDDEF_00630	5.77e-244	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCKBDDEF_00631	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCKBDDEF_00632	1.61e-88	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MCKBDDEF_00633	9.42e-29	ymzA	-	-	-	-	-	-	-
MCKBDDEF_00634	2.86e-57	-	-	-	-	-	-	-	-
MCKBDDEF_00635	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MCKBDDEF_00636	7.32e-219	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MCKBDDEF_00637	5.96e-77	ymaF	-	-	S	-	-	-	YmaF family
MCKBDDEF_00639	1.82e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MCKBDDEF_00640	5.05e-70	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MCKBDDEF_00641	1.11e-100	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MCKBDDEF_00642	5.4e-161	ymaC	-	-	S	-	-	-	Replication protein
MCKBDDEF_00643	4.29e-06	-	-	-	-	-	-	-	-
MCKBDDEF_00644	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
MCKBDDEF_00645	2.78e-82	ymzB	-	-	-	-	-	-	-
MCKBDDEF_00646	4.46e-153	yoaK	-	-	S	-	-	-	Membrane
MCKBDDEF_00647	4.27e-102	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MCKBDDEF_00648	6.55e-292	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MCKBDDEF_00649	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
MCKBDDEF_00650	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MCKBDDEF_00651	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00652	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00653	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MCKBDDEF_00654	3.42e-180	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MCKBDDEF_00655	5.05e-186	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
MCKBDDEF_00656	3.63e-309	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MCKBDDEF_00657	5.27e-49	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
MCKBDDEF_00658	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MCKBDDEF_00659	3.7e-233	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
MCKBDDEF_00660	1.35e-206	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MCKBDDEF_00661	1.16e-165	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
MCKBDDEF_00663	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MCKBDDEF_00664	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MCKBDDEF_00665	7.09e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MCKBDDEF_00666	2.11e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MCKBDDEF_00667	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MCKBDDEF_00668	7.11e-274	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MCKBDDEF_00669	8.3e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MCKBDDEF_00670	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MCKBDDEF_00671	3.72e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MCKBDDEF_00672	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MCKBDDEF_00673	5.01e-275	pbpX	-	-	V	-	-	-	Beta-lactamase
MCKBDDEF_00674	3.06e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MCKBDDEF_00675	4.64e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MCKBDDEF_00676	9.58e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MCKBDDEF_00677	5.76e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MCKBDDEF_00678	3.14e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MCKBDDEF_00679	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MCKBDDEF_00680	2.88e-164	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MCKBDDEF_00681	8.28e-310	ymfH	-	-	S	-	-	-	zinc protease
MCKBDDEF_00682	1.12e-306	albE	-	-	S	-	-	-	Peptidase M16
MCKBDDEF_00683	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
MCKBDDEF_00684	9.88e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MCKBDDEF_00685	3.16e-296	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_00686	4.48e-172	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_00687	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MCKBDDEF_00688	6.32e-42	-	-	-	S	-	-	-	YlzJ-like protein
MCKBDDEF_00689	2.27e-166	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MCKBDDEF_00690	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MCKBDDEF_00691	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MCKBDDEF_00692	2e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MCKBDDEF_00693	1.74e-249	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MCKBDDEF_00694	1.36e-137	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MCKBDDEF_00695	4.51e-204	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
MCKBDDEF_00696	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
MCKBDDEF_00697	5.91e-299	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MCKBDDEF_00698	4.15e-232	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MCKBDDEF_00699	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MCKBDDEF_00700	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MCKBDDEF_00701	2.6e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MCKBDDEF_00702	1.73e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MCKBDDEF_00703	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MCKBDDEF_00704	3.88e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MCKBDDEF_00705	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MCKBDDEF_00706	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MCKBDDEF_00707	6.76e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MCKBDDEF_00708	4.04e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MCKBDDEF_00709	1.9e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MCKBDDEF_00710	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MCKBDDEF_00711	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MCKBDDEF_00712	1.15e-296	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MCKBDDEF_00713	2.57e-272	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MCKBDDEF_00714	3.8e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MCKBDDEF_00715	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MCKBDDEF_00716	1.94e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MCKBDDEF_00717	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MCKBDDEF_00718	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MCKBDDEF_00719	7.07e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MCKBDDEF_00720	5.85e-94	ylxL	-	-	-	-	-	-	-
MCKBDDEF_00721	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCKBDDEF_00722	2.86e-113	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MCKBDDEF_00723	3.42e-142	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MCKBDDEF_00724	2.49e-105	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
MCKBDDEF_00725	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MCKBDDEF_00726	1.42e-248	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MCKBDDEF_00727	6.35e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
MCKBDDEF_00728	7.94e-250	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MCKBDDEF_00729	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MCKBDDEF_00730	2.53e-242	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MCKBDDEF_00731	5.74e-168	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MCKBDDEF_00732	3.15e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MCKBDDEF_00733	1.48e-142	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MCKBDDEF_00734	9.34e-144	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MCKBDDEF_00735	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
MCKBDDEF_00736	8.47e-245	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MCKBDDEF_00737	5.43e-230	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MCKBDDEF_00738	1.81e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MCKBDDEF_00739	2.79e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MCKBDDEF_00740	8.9e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MCKBDDEF_00741	3e-260	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
MCKBDDEF_00742	1.98e-88	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
MCKBDDEF_00743	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
MCKBDDEF_00744	5.19e-309	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MCKBDDEF_00745	1.96e-122	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MCKBDDEF_00746	2.48e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MCKBDDEF_00747	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MCKBDDEF_00748	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MCKBDDEF_00749	8.81e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MCKBDDEF_00750	2.8e-84	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MCKBDDEF_00751	2.77e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MCKBDDEF_00752	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MCKBDDEF_00753	7.38e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MCKBDDEF_00754	6.29e-220	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MCKBDDEF_00755	3.83e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MCKBDDEF_00756	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MCKBDDEF_00757	7.32e-216	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MCKBDDEF_00758	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MCKBDDEF_00759	2.02e-270	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MCKBDDEF_00760	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
MCKBDDEF_00761	0.0	ylqG	-	-	-	-	-	-	-
MCKBDDEF_00762	3.37e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCKBDDEF_00763	5.09e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MCKBDDEF_00764	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MCKBDDEF_00765	5.67e-176	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MCKBDDEF_00766	1.51e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MCKBDDEF_00767	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
MCKBDDEF_00768	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MCKBDDEF_00769	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MCKBDDEF_00770	1.47e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MCKBDDEF_00771	8.01e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MCKBDDEF_00772	1.57e-184	-	-	-	S	-	-	-	Phosphotransferase enzyme family
MCKBDDEF_00773	1.87e-224	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MCKBDDEF_00774	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MCKBDDEF_00775	1.23e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MCKBDDEF_00776	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MCKBDDEF_00777	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MCKBDDEF_00778	3.76e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MCKBDDEF_00779	3.14e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MCKBDDEF_00780	4.38e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MCKBDDEF_00781	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MCKBDDEF_00782	9.75e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MCKBDDEF_00783	4.15e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MCKBDDEF_00784	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MCKBDDEF_00785	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_00786	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MCKBDDEF_00787	4.34e-152	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MCKBDDEF_00788	3.42e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MCKBDDEF_00789	6.22e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MCKBDDEF_00790	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MCKBDDEF_00791	2.03e-177	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MCKBDDEF_00792	1.52e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MCKBDDEF_00793	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MCKBDDEF_00794	2.64e-221	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MCKBDDEF_00795	2.89e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MCKBDDEF_00796	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MCKBDDEF_00797	2.09e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MCKBDDEF_00798	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MCKBDDEF_00799	4.91e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MCKBDDEF_00800	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MCKBDDEF_00801	2.14e-198	yloC	-	-	S	-	-	-	stress-induced protein
MCKBDDEF_00802	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MCKBDDEF_00803	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MCKBDDEF_00804	6.27e-106	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MCKBDDEF_00805	4.15e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
MCKBDDEF_00806	5.9e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MCKBDDEF_00807	6.76e-143	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MCKBDDEF_00808	1.77e-283	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MCKBDDEF_00809	1.21e-228	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MCKBDDEF_00810	9.88e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MCKBDDEF_00812	8.96e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MCKBDDEF_00813	3.66e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MCKBDDEF_00814	7.36e-222	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MCKBDDEF_00815	1.18e-179	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MCKBDDEF_00816	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MCKBDDEF_00817	8.86e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MCKBDDEF_00818	1.55e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MCKBDDEF_00819	1.47e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MCKBDDEF_00820	2.81e-296	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MCKBDDEF_00821	8.98e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MCKBDDEF_00822	5.35e-216	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MCKBDDEF_00823	1.02e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MCKBDDEF_00824	4.75e-80	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MCKBDDEF_00825	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MCKBDDEF_00826	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MCKBDDEF_00827	6.12e-182	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MCKBDDEF_00828	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MCKBDDEF_00829	4.61e-85	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MCKBDDEF_00830	3.68e-161	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MCKBDDEF_00831	9.55e-206	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MCKBDDEF_00832	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
MCKBDDEF_00833	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MCKBDDEF_00834	8.04e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MCKBDDEF_00835	9.33e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCKBDDEF_00836	7.35e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCKBDDEF_00837	8.23e-218	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MCKBDDEF_00838	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
MCKBDDEF_00839	2.61e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MCKBDDEF_00840	1.57e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MCKBDDEF_00841	2.67e-179	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MCKBDDEF_00842	7.87e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MCKBDDEF_00843	3.29e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MCKBDDEF_00844	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MCKBDDEF_00845	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MCKBDDEF_00846	7.04e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MCKBDDEF_00847	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MCKBDDEF_00848	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MCKBDDEF_00849	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MCKBDDEF_00850	2.4e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
MCKBDDEF_00851	8.23e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MCKBDDEF_00852	1.03e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MCKBDDEF_00853	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MCKBDDEF_00854	2.85e-210	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MCKBDDEF_00855	1.14e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
MCKBDDEF_00856	1.27e-110	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MCKBDDEF_00857	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MCKBDDEF_00858	3.3e-115	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MCKBDDEF_00859	5.23e-295	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MCKBDDEF_00860	8.8e-240	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MCKBDDEF_00861	2.48e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MCKBDDEF_00862	9.73e-276	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MCKBDDEF_00863	8.3e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MCKBDDEF_00864	7.68e-116	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MCKBDDEF_00865	3.94e-57	ylbG	-	-	S	-	-	-	UPF0298 protein
MCKBDDEF_00866	2.74e-96	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MCKBDDEF_00867	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
MCKBDDEF_00868	1.03e-87	ylbD	-	-	S	-	-	-	Putative coat protein
MCKBDDEF_00869	3.97e-255	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MCKBDDEF_00870	9.59e-96	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
MCKBDDEF_00871	4.12e-79	ylbA	-	-	S	-	-	-	YugN-like family
MCKBDDEF_00872	8.46e-211	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MCKBDDEF_00873	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MCKBDDEF_00874	5.92e-142	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MCKBDDEF_00875	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MCKBDDEF_00876	3.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MCKBDDEF_00877	2.07e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MCKBDDEF_00878	3.47e-214	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MCKBDDEF_00879	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MCKBDDEF_00880	8.59e-272	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MCKBDDEF_00881	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MCKBDDEF_00882	5.18e-221	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MCKBDDEF_00883	1.75e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MCKBDDEF_00884	2.7e-313	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MCKBDDEF_00885	5.45e-138	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MCKBDDEF_00886	6.78e-46	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_00887	2.44e-65	-	-	-	S	-	-	-	YlaH-like protein
MCKBDDEF_00888	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MCKBDDEF_00889	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MCKBDDEF_00890	2.83e-62	ylaE	-	-	-	-	-	-	-
MCKBDDEF_00892	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MCKBDDEF_00893	1.07e-107	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MCKBDDEF_00894	7.8e-194	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MCKBDDEF_00895	3.33e-33	ykzI	-	-	-	-	-	-	-
MCKBDDEF_00896	8.15e-155	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MCKBDDEF_00897	3.83e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MCKBDDEF_00898	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MCKBDDEF_00899	8.08e-192	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MCKBDDEF_00900	7.97e-59	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MCKBDDEF_00901	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MCKBDDEF_00902	2.08e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MCKBDDEF_00903	1.01e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MCKBDDEF_00904	6.68e-262	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MCKBDDEF_00905	3.73e-264	-	-	-	V	-	-	-	Beta-lactamase
MCKBDDEF_00906	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
MCKBDDEF_00907	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00908	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00909	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00910	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00911	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
MCKBDDEF_00912	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MCKBDDEF_00913	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MCKBDDEF_00914	1.32e-132	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MCKBDDEF_00915	7.91e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MCKBDDEF_00916	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MCKBDDEF_00917	1.51e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MCKBDDEF_00918	4.45e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MCKBDDEF_00919	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MCKBDDEF_00920	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MCKBDDEF_00921	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MCKBDDEF_00922	5.27e-197	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
MCKBDDEF_00923	1.68e-312	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MCKBDDEF_00924	6.37e-60	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
MCKBDDEF_00925	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MCKBDDEF_00926	4.47e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
MCKBDDEF_00927	1.2e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MCKBDDEF_00928	1.08e-214	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MCKBDDEF_00929	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MCKBDDEF_00930	3.68e-50	ykoA	-	-	-	-	-	-	-
MCKBDDEF_00931	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MCKBDDEF_00932	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MCKBDDEF_00933	5.54e-213	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MCKBDDEF_00934	9.28e-170	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_00935	2.98e-269	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MCKBDDEF_00936	2.38e-157	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_00937	1.64e-245	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MCKBDDEF_00938	7.69e-139	yknW	-	-	S	-	-	-	Yip1 domain
MCKBDDEF_00939	2.06e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MCKBDDEF_00940	7.17e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MCKBDDEF_00941	3.21e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MCKBDDEF_00942	2.78e-309	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MCKBDDEF_00943	1.41e-240	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MCKBDDEF_00944	1.93e-139	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MCKBDDEF_00945	6.93e-216	yknT	-	-	-	ko:K06437	-	ko00000	-
MCKBDDEF_00946	3.04e-126	rok	-	-	K	-	-	-	Repressor of ComK
MCKBDDEF_00947	1.92e-102	ykuV	-	-	CO	-	-	-	thiol-disulfide
MCKBDDEF_00948	1.73e-178	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MCKBDDEF_00949	2.15e-52	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MCKBDDEF_00950	7.99e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MCKBDDEF_00951	2.89e-129	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MCKBDDEF_00952	2.16e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MCKBDDEF_00953	1.95e-219	ykuO	-	-	-	-	-	-	-
MCKBDDEF_00954	6.12e-115	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MCKBDDEF_00955	1.32e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_00956	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
MCKBDDEF_00957	3.09e-35	ykzF	-	-	S	-	-	-	Antirepressor AbbA
MCKBDDEF_00958	4.35e-120	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
MCKBDDEF_00959	3.63e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_00960	1.82e-295	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MCKBDDEF_00962	1.5e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCKBDDEF_00963	3.66e-197	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
MCKBDDEF_00964	2.55e-116	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_00965	4.6e-308	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_00966	5.07e-108	ykyB	-	-	S	-	-	-	YkyB-like protein
MCKBDDEF_00967	3.2e-212	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MCKBDDEF_00968	6.38e-15	-	-	-	-	-	-	-	-
MCKBDDEF_00969	3.28e-275	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MCKBDDEF_00970	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_00971	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MCKBDDEF_00972	2.94e-168	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
MCKBDDEF_00973	1.4e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MCKBDDEF_00974	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MCKBDDEF_00975	3.53e-256	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MCKBDDEF_00976	3.63e-50	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_00977	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MCKBDDEF_00978	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MCKBDDEF_00979	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MCKBDDEF_00980	4.61e-198	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MCKBDDEF_00981	1.01e-224	ykvZ	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_00983	4.71e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MCKBDDEF_00984	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MCKBDDEF_00985	8.57e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
MCKBDDEF_00986	2.66e-306	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCKBDDEF_00987	8.42e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MCKBDDEF_00988	7.17e-39	-	-	-	-	-	-	-	-
MCKBDDEF_00989	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_00990	6e-59	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
MCKBDDEF_00991	3.91e-42	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MCKBDDEF_00992	2.47e-168	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MCKBDDEF_00993	2.54e-77	ykvN	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_00995	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MCKBDDEF_00996	1.76e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MCKBDDEF_00997	6.25e-103	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MCKBDDEF_00998	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MCKBDDEF_00999	6.57e-254	-	-	-	-	-	-	-	-
MCKBDDEF_01000	1.73e-228	ykvI	-	-	S	-	-	-	membrane
MCKBDDEF_01001	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MCKBDDEF_01002	7.27e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MCKBDDEF_01003	4.04e-169	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MCKBDDEF_01004	3.91e-100	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MCKBDDEF_01005	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MCKBDDEF_01007	2.05e-121	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MCKBDDEF_01008	2.61e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MCKBDDEF_01009	9.47e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MCKBDDEF_01010	7.51e-287	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MCKBDDEF_01011	1.04e-290	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MCKBDDEF_01012	1.57e-190	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MCKBDDEF_01013	2.44e-287	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MCKBDDEF_01014	4.44e-251	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MCKBDDEF_01016	1.31e-113	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MCKBDDEF_01017	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_01018	3.74e-241	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
MCKBDDEF_01019	3.07e-32	ykzE	-	-	-	-	-	-	-
MCKBDDEF_01020	3e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
MCKBDDEF_01021	1.62e-309	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MCKBDDEF_01022	6.35e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MCKBDDEF_01023	1.62e-161	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
MCKBDDEF_01024	5.7e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
MCKBDDEF_01025	3.6e-250	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
MCKBDDEF_01026	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCKBDDEF_01027	2.91e-173	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MCKBDDEF_01028	1.43e-131	ykoX	-	-	S	-	-	-	membrane-associated protein
MCKBDDEF_01029	3.42e-202	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MCKBDDEF_01030	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MCKBDDEF_01031	3.81e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MCKBDDEF_01032	5.46e-105	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MCKBDDEF_01033	5.25e-37	ykoL	-	-	-	-	-	-	-
MCKBDDEF_01034	1.11e-23	-	-	-	-	-	-	-	-
MCKBDDEF_01035	1.23e-69	tnrA	-	-	K	-	-	-	transcriptional
MCKBDDEF_01036	3.52e-309	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MCKBDDEF_01038	1.27e-309	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
MCKBDDEF_01039	4.66e-126	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MCKBDDEF_01040	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_01041	2.18e-169	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MCKBDDEF_01042	1.28e-189	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MCKBDDEF_01043	2.58e-226	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MCKBDDEF_01044	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MCKBDDEF_01045	1.98e-133	-	-	-	S	-	-	-	AAA ATPase domain
MCKBDDEF_01046	1.78e-175	-	-	-	M	-	-	-	PFAM Collagen triple helix repeat (20 copies)
MCKBDDEF_01047	7.1e-275	-	-	-	M	-	-	-	Glycosyl transferase family 2
MCKBDDEF_01049	6.7e-82	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MCKBDDEF_01050	3.2e-91	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MCKBDDEF_01051	9.88e-111	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
MCKBDDEF_01052	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MCKBDDEF_01053	7.94e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MCKBDDEF_01054	1.77e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MCKBDDEF_01055	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MCKBDDEF_01056	4.97e-64	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MCKBDDEF_01057	2.37e-68	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MCKBDDEF_01058	7.43e-130	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MCKBDDEF_01059	3.06e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
MCKBDDEF_01060	3.44e-203	ykgA	-	-	E	-	-	-	Amidinotransferase
MCKBDDEF_01061	3.43e-262	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MCKBDDEF_01062	6.62e-231	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_01063	2.55e-216	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MCKBDDEF_01064	4.3e-255	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MCKBDDEF_01065	1.09e-223	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MCKBDDEF_01066	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MCKBDDEF_01067	4.37e-241	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_01068	1.89e-226	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCKBDDEF_01069	3.98e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCKBDDEF_01070	4.36e-200	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MCKBDDEF_01071	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
MCKBDDEF_01072	1.07e-275	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MCKBDDEF_01074	1.56e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MCKBDDEF_01075	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MCKBDDEF_01076	4.3e-228	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MCKBDDEF_01077	2.64e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MCKBDDEF_01078	1.2e-140	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
MCKBDDEF_01079	1.22e-226	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MCKBDDEF_01080	1.89e-172	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MCKBDDEF_01081	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
MCKBDDEF_01082	2.02e-214	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MCKBDDEF_01083	4.7e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
MCKBDDEF_01084	3.87e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MCKBDDEF_01085	3.67e-177	xepA	-	-	-	-	-	-	-
MCKBDDEF_01086	1.32e-39	xkdX	-	-	-	-	-	-	-
MCKBDDEF_01088	4.87e-109	-	-	-	-	-	-	-	-
MCKBDDEF_01089	8.92e-38	-	-	-	-	-	-	-	-
MCKBDDEF_01090	4.1e-112	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MCKBDDEF_01091	4.38e-212	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MCKBDDEF_01092	4.74e-75	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MCKBDDEF_01093	2.51e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MCKBDDEF_01094	2.66e-206	xkdQ	-	-	G	-	-	-	NLP P60 protein
MCKBDDEF_01095	6.56e-145	xkdP	-	-	S	-	-	-	Lysin motif
MCKBDDEF_01096	5.5e-272	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MCKBDDEF_01097	4.33e-27	-	-	-	-	-	-	-	-
MCKBDDEF_01098	2.09e-95	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MCKBDDEF_01099	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
MCKBDDEF_01100	2.31e-287	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MCKBDDEF_01101	1.45e-20	-	-	-	-	-	-	-	-
MCKBDDEF_01102	1.05e-74	xkdJ	-	-	-	-	-	-	-
MCKBDDEF_01103	8.03e-76	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MCKBDDEF_01104	1.42e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MCKBDDEF_01105	3.6e-60	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MCKBDDEF_01106	8.3e-203	xkdG	-	-	S	-	-	-	Phage capsid family
MCKBDDEF_01107	8.8e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MCKBDDEF_01108	5.17e-304	xkdE3	-	-	S	-	-	-	portal protein
MCKBDDEF_01109	1.36e-262	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MCKBDDEF_01110	1.24e-142	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
MCKBDDEF_01111	3.05e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MCKBDDEF_01115	2.94e-194	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
MCKBDDEF_01117	6.52e-75	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MCKBDDEF_01118	6.51e-145	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MCKBDDEF_01119	2.63e-142	yjqB	-	-	S	-	-	-	phage-related replication protein
MCKBDDEF_01120	9.51e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
MCKBDDEF_01121	1.94e-220	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MCKBDDEF_01123	2.68e-275	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MCKBDDEF_01124	8.38e-103	yjoA	-	-	S	-	-	-	DinB family
MCKBDDEF_01125	3.21e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MCKBDDEF_01126	3.25e-243	lcnDR2	-	-	V	-	-	-	Domain of unknown function (DUF4135)
MCKBDDEF_01129	2.77e-276	lanT	-	-	V	ko:K06148,ko:K13409,ko:K20344,ko:K20386	ko02010,ko02024,ko04626,map02010,map02024,map04626	ko00000,ko00001,ko00002,ko02000,ko02044	Peptidase C39 family
MCKBDDEF_01130	0.0	lcnDR2	-	-	V	-	-	-	Lanthionine synthetase C-like protein
MCKBDDEF_01132	1.26e-75	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCKBDDEF_01133	4.67e-50	-	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_01135	7.74e-86	-	-	-	S	-	-	-	ABC-2 family transporter protein
MCKBDDEF_01136	1.11e-132	-	-	-	V	ko:K01990,ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_01137	4.91e-167	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MCKBDDEF_01138	1.83e-112	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MCKBDDEF_01139	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MCKBDDEF_01140	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MCKBDDEF_01141	1.24e-235	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MCKBDDEF_01142	0.0	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
MCKBDDEF_01143	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MCKBDDEF_01144	1.76e-279	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MCKBDDEF_01145	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MCKBDDEF_01146	4.96e-118	yjlB	-	-	S	-	-	-	Cupin domain
MCKBDDEF_01147	2.38e-226	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MCKBDDEF_01148	3.08e-166	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_01149	3.6e-158	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
MCKBDDEF_01150	4.13e-188	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MCKBDDEF_01151	1.73e-40	-	-	-	-	-	-	-	-
MCKBDDEF_01152	1.64e-283	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MCKBDDEF_01153	3.25e-291	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MCKBDDEF_01154	2.2e-117	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MCKBDDEF_01155	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
MCKBDDEF_01156	3.92e-129	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
MCKBDDEF_01157	1.48e-90	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
MCKBDDEF_01158	1.91e-31	yjfB	-	-	S	-	-	-	Putative motility protein
MCKBDDEF_01160	2.89e-135	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MCKBDDEF_01161	1.19e-68	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MCKBDDEF_01162	1.69e-46	-	-	-	-	-	-	-	-
MCKBDDEF_01163	1.62e-158	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MCKBDDEF_01164	1.62e-176	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MCKBDDEF_01165	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MCKBDDEF_01166	8.91e-67	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MCKBDDEF_01167	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCKBDDEF_01168	4.28e-274	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MCKBDDEF_01169	2.09e-242	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MCKBDDEF_01170	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MCKBDDEF_01171	1.34e-281	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MCKBDDEF_01172	1.06e-106	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MCKBDDEF_01173	0.0	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
MCKBDDEF_01174	3.12e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MCKBDDEF_01175	1.64e-210	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
MCKBDDEF_01176	3.27e-78	-	-	-	E	-	-	-	Glyoxalase-like domain
MCKBDDEF_01180	4.74e-247	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
MCKBDDEF_01182	9.34e-51	-	-	-	-	-	-	-	-
MCKBDDEF_01183	1.42e-29	-	-	-	-	-	-	-	-
MCKBDDEF_01184	1.14e-26	-	-	-	-	-	-	-	-
MCKBDDEF_01186	1.37e-271	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MCKBDDEF_01187	3.93e-271	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MCKBDDEF_01188	1.23e-164	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MCKBDDEF_01189	6.97e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MCKBDDEF_01190	2.48e-96	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCKBDDEF_01191	4.32e-48	-	-	-	K	-	-	-	SpoVT / AbrB like domain
MCKBDDEF_01192	3.53e-171	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MCKBDDEF_01193	4.59e-160	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MCKBDDEF_01194	2.06e-181	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MCKBDDEF_01195	2.48e-48	-	-	-	-	-	-	-	-
MCKBDDEF_01196	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MCKBDDEF_01197	2.57e-51	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
MCKBDDEF_01198	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MCKBDDEF_01201	8.37e-73	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MCKBDDEF_01202	9.7e-71	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
MCKBDDEF_01203	4.1e-43	cotW	-	-	-	ko:K06341	-	ko00000	-
MCKBDDEF_01204	1.51e-99	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MCKBDDEF_01205	2.48e-120	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
MCKBDDEF_01206	2.1e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
MCKBDDEF_01207	7.96e-124	yjbX	-	-	S	-	-	-	Spore coat protein
MCKBDDEF_01208	6.85e-180	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MCKBDDEF_01209	4.3e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MCKBDDEF_01210	1.52e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MCKBDDEF_01211	1.81e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MCKBDDEF_01212	5.5e-42	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
MCKBDDEF_01213	4.57e-268	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MCKBDDEF_01214	8.09e-139	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
MCKBDDEF_01215	5.26e-175	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MCKBDDEF_01216	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MCKBDDEF_01217	3.05e-183	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MCKBDDEF_01218	2.35e-211	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MCKBDDEF_01219	2.07e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MCKBDDEF_01220	1.56e-139	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MCKBDDEF_01221	4.78e-79	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MCKBDDEF_01222	1.72e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_01223	3.12e-152	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MCKBDDEF_01224	2.03e-92	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
MCKBDDEF_01225	1.22e-219	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MCKBDDEF_01226	1.06e-25	-	-	-	-	-	-	-	-
MCKBDDEF_01227	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MCKBDDEF_01228	9.45e-281	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MCKBDDEF_01229	9.78e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MCKBDDEF_01230	4.59e-140	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
MCKBDDEF_01231	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MCKBDDEF_01232	2.55e-131	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCKBDDEF_01233	3.5e-295	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
MCKBDDEF_01234	1.42e-216	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_01235	1.5e-256	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_01236	6.93e-208	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCKBDDEF_01237	1.46e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCKBDDEF_01238	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MCKBDDEF_01239	4.85e-232	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MCKBDDEF_01240	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MCKBDDEF_01241	1.67e-198	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCKBDDEF_01242	5.76e-217	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCKBDDEF_01243	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MCKBDDEF_01244	7.23e-238	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_01245	8.37e-232	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_01246	7.48e-190	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MCKBDDEF_01247	9.08e-299	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MCKBDDEF_01248	3.78e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MCKBDDEF_01249	2.72e-42	yjzB	-	-	-	-	-	-	-
MCKBDDEF_01250	6.46e-37	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
MCKBDDEF_01251	4.67e-213	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
MCKBDDEF_01252	1.67e-134	yjaV	-	-	-	-	-	-	-
MCKBDDEF_01253	3.04e-176	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MCKBDDEF_01254	1.24e-31	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MCKBDDEF_01255	7.21e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
MCKBDDEF_01256	8.28e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MCKBDDEF_01257	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MCKBDDEF_01258	2.31e-257	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MCKBDDEF_01259	3.98e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MCKBDDEF_01260	5.17e-175	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MCKBDDEF_01261	2.99e-289	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MCKBDDEF_01262	5.84e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MCKBDDEF_01263	1.18e-121	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MCKBDDEF_01264	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
MCKBDDEF_01265	1.12e-103	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MCKBDDEF_01266	1.33e-67	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MCKBDDEF_01267	8.73e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MCKBDDEF_01268	5.08e-197	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MCKBDDEF_01269	1.49e-11	-	-	-	-	-	-	-	-
MCKBDDEF_01270	1.5e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
MCKBDDEF_01271	6.41e-106	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
MCKBDDEF_01272	4.62e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MCKBDDEF_01273	5.5e-203	yitS	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_01275	1.79e-307	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MCKBDDEF_01276	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MCKBDDEF_01277	8.51e-219	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
MCKBDDEF_01278	7.54e-205	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MCKBDDEF_01279	3.69e-78	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
MCKBDDEF_01280	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MCKBDDEF_01281	1.8e-104	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MCKBDDEF_01282	1.6e-103	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MCKBDDEF_01283	5.57e-238	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MCKBDDEF_01284	1.71e-95	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
MCKBDDEF_01285	1.48e-114	yisT	-	-	S	-	-	-	DinB family
MCKBDDEF_01286	4.31e-31	-	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
MCKBDDEF_01287	4.72e-206	yisR	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_01288	6.12e-312	yisQ	-	-	V	-	-	-	Mate efflux family protein
MCKBDDEF_01289	1.81e-169	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
MCKBDDEF_01290	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MCKBDDEF_01291	2.17e-123	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MCKBDDEF_01292	2.22e-78	yisL	-	-	S	-	-	-	UPF0344 protein
MCKBDDEF_01293	1.54e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MCKBDDEF_01294	1.59e-11	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MCKBDDEF_01295	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
MCKBDDEF_01296	6.59e-48	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
MCKBDDEF_01297	8.51e-109	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
MCKBDDEF_01298	3e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
MCKBDDEF_01299	1.09e-82	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
MCKBDDEF_01300	6.66e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
MCKBDDEF_01301	6.24e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
MCKBDDEF_01302	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
MCKBDDEF_01303	4.7e-283	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MCKBDDEF_01304	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MCKBDDEF_01305	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MCKBDDEF_01306	5.11e-153	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MCKBDDEF_01307	3.6e-122	yhjR	-	-	S	-	-	-	Rubrerythrin
MCKBDDEF_01308	1.06e-139	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
MCKBDDEF_01309	1.78e-266	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_01310	9.85e-262	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
MCKBDDEF_01311	4.89e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MCKBDDEF_01312	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
MCKBDDEF_01313	3.32e-119	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MCKBDDEF_01314	2.23e-142	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
MCKBDDEF_01315	4.12e-79	yhjD	-	-	-	-	-	-	-
MCKBDDEF_01316	5.59e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MCKBDDEF_01317	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MCKBDDEF_01318	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
MCKBDDEF_01319	1.23e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
MCKBDDEF_01320	1.49e-161	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
MCKBDDEF_01321	4.93e-82	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MCKBDDEF_01322	2.09e-87	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MCKBDDEF_01323	1.09e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
MCKBDDEF_01324	3.87e-42	yhzC	-	-	S	-	-	-	IDEAL
MCKBDDEF_01325	3.88e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCKBDDEF_01326	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MCKBDDEF_01327	1.87e-275	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MCKBDDEF_01328	7.56e-116	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MCKBDDEF_01329	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MCKBDDEF_01330	2.38e-251	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MCKBDDEF_01331	6.03e-134	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MCKBDDEF_01332	7.33e-192	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MCKBDDEF_01333	1.57e-261	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MCKBDDEF_01334	3.56e-298	yhfN	-	-	O	-	-	-	Peptidase M48
MCKBDDEF_01335	7.96e-85	yhfM	-	-	-	-	-	-	-
MCKBDDEF_01336	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MCKBDDEF_01337	1.05e-141	yhfK	-	-	GM	-	-	-	NmrA-like family
MCKBDDEF_01338	6.47e-242	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MCKBDDEF_01339	4.01e-181	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MCKBDDEF_01341	3.43e-282	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCKBDDEF_01342	2.11e-250	yhfE	-	-	G	-	-	-	peptidase M42
MCKBDDEF_01344	5.92e-235	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MCKBDDEF_01345	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MCKBDDEF_01346	4.41e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_01347	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MCKBDDEF_01348	4.49e-232	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MCKBDDEF_01349	8.58e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MCKBDDEF_01350	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MCKBDDEF_01351	3.1e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MCKBDDEF_01352	3.98e-311	yhfA	-	-	C	-	-	-	membrane
MCKBDDEF_01353	1.53e-286	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MCKBDDEF_01354	1.75e-161	ecsC	-	-	S	-	-	-	EcsC protein family
MCKBDDEF_01355	6.41e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MCKBDDEF_01356	3.02e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MCKBDDEF_01357	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MCKBDDEF_01358	5.91e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MCKBDDEF_01359	1.43e-100	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
MCKBDDEF_01360	2.55e-24	-	-	-	-	-	-	-	-
MCKBDDEF_01361	4.74e-55	yhaH	-	-	S	-	-	-	YtxH-like protein
MCKBDDEF_01362	4.73e-146	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MCKBDDEF_01363	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
MCKBDDEF_01364	1.29e-123	yhaK	-	-	S	-	-	-	Putative zincin peptidase
MCKBDDEF_01365	1.36e-183	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MCKBDDEF_01366	4.95e-44	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MCKBDDEF_01367	2.48e-226	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MCKBDDEF_01368	0.0	yhaN	-	-	L	-	-	-	AAA domain
MCKBDDEF_01369	7.47e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
MCKBDDEF_01370	4.82e-277	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MCKBDDEF_01371	3.92e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_01372	5.99e-21	-	-	-	S	-	-	-	YhzD-like protein
MCKBDDEF_01373	1.18e-174	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
MCKBDDEF_01375	3.62e-111	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MCKBDDEF_01376	1.41e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
MCKBDDEF_01377	0.0	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
MCKBDDEF_01378	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
MCKBDDEF_01379	2.95e-205	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MCKBDDEF_01380	1.74e-258	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
MCKBDDEF_01381	2.32e-70	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MCKBDDEF_01382	7.84e-264	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MCKBDDEF_01383	1.54e-272	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MCKBDDEF_01384	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MCKBDDEF_01385	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
MCKBDDEF_01386	3.3e-39	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MCKBDDEF_01388	7.8e-142	yheG	-	-	GM	-	-	-	NAD(P)H-binding
MCKBDDEF_01389	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MCKBDDEF_01390	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MCKBDDEF_01392	2.49e-110	-	-	-	T	-	-	-	universal stress protein
MCKBDDEF_01393	3.12e-123	ymcC	-	-	S	-	-	-	Membrane
MCKBDDEF_01394	1.43e-113	pksA	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_01395	3.99e-196	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MCKBDDEF_01396	4.01e-200	nodB1	-	-	G	-	-	-	deacetylase
MCKBDDEF_01397	7.18e-181	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MCKBDDEF_01398	4.51e-260	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MCKBDDEF_01399	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
MCKBDDEF_01400	1.49e-164	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MCKBDDEF_01401	4.97e-79	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCKBDDEF_01402	2.9e-70	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCKBDDEF_01403	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MCKBDDEF_01404	9.1e-300	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MCKBDDEF_01405	4.05e-286	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MCKBDDEF_01406	1.19e-93	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
MCKBDDEF_01407	2.28e-306	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MCKBDDEF_01408	9.21e-142	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MCKBDDEF_01409	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MCKBDDEF_01410	6.88e-257	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
MCKBDDEF_01411	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
MCKBDDEF_01412	8.02e-265	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MCKBDDEF_01413	1.78e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
MCKBDDEF_01414	1.58e-205	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCKBDDEF_01415	6.39e-259	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MCKBDDEF_01416	8.17e-209	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_01417	2.8e-171	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MCKBDDEF_01418	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MCKBDDEF_01419	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MCKBDDEF_01420	0.0	ygxB	-	-	M	-	-	-	Conserved TM helix
MCKBDDEF_01421	3.79e-96	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MCKBDDEF_01422	1.04e-297	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MCKBDDEF_01423	2.94e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MCKBDDEF_01424	1.16e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
MCKBDDEF_01425	9.77e-116	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
MCKBDDEF_01426	1.56e-143	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCKBDDEF_01427	8.75e-262	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_01428	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MCKBDDEF_01429	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MCKBDDEF_01430	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MCKBDDEF_01431	2.83e-199	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MCKBDDEF_01432	5.16e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MCKBDDEF_01433	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MCKBDDEF_01434	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MCKBDDEF_01435	3.41e-161	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MCKBDDEF_01436	6.12e-91	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MCKBDDEF_01437	7.37e-90	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
MCKBDDEF_01438	2.27e-216	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MCKBDDEF_01439	1.3e-136	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MCKBDDEF_01440	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MCKBDDEF_01441	4.45e-151	yhcQ	-	-	M	-	-	-	Spore coat protein
MCKBDDEF_01442	1.85e-204	yhcP	-	-	-	-	-	-	-
MCKBDDEF_01443	2.69e-122	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MCKBDDEF_01444	1.74e-72	yhcM	-	-	-	-	-	-	-
MCKBDDEF_01445	4.31e-292	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCKBDDEF_01446	1.01e-234	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
MCKBDDEF_01447	5.86e-190	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MCKBDDEF_01448	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MCKBDDEF_01449	2.23e-209	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MCKBDDEF_01450	1.6e-89	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_01451	1.41e-72	yhcC	-	-	-	-	-	-	-
MCKBDDEF_01452	9.09e-129	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MCKBDDEF_01453	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MCKBDDEF_01454	1.54e-132	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
MCKBDDEF_01455	4.15e-98	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
MCKBDDEF_01456	5.45e-279	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MCKBDDEF_01457	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MCKBDDEF_01458	1.23e-07	-	-	-	-	-	-	-	-
MCKBDDEF_01459	2.02e-94	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MCKBDDEF_01460	3.99e-85	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MCKBDDEF_01461	4.63e-139	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
MCKBDDEF_01462	4.84e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MCKBDDEF_01463	2.08e-225	yhbB	-	-	S	-	-	-	Putative amidase domain
MCKBDDEF_01464	2.08e-287	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MCKBDDEF_01465	7.82e-147	yhzB	-	-	S	-	-	-	B3/4 domain
MCKBDDEF_01467	9.41e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_01468	1.29e-106	ygaO	-	-	-	-	-	-	-
MCKBDDEF_01469	3.39e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCKBDDEF_01470	1.17e-270	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MCKBDDEF_01471	8.27e-186	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MCKBDDEF_01472	7.12e-229	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
MCKBDDEF_01473	1.5e-178	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MCKBDDEF_01474	4.68e-234	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
MCKBDDEF_01475	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MCKBDDEF_01476	3.29e-168	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_01477	3.14e-169	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_01478	8.8e-162	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCKBDDEF_01479	1.17e-178	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MCKBDDEF_01480	9.91e-288	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
MCKBDDEF_01482	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
MCKBDDEF_01483	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MCKBDDEF_01484	1.57e-172	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MCKBDDEF_01485	4.79e-259	-	-	-	C	-	-	-	Na+/H+ antiporter family
MCKBDDEF_01502	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MCKBDDEF_01503	1.12e-212	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
MCKBDDEF_01504	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
MCKBDDEF_01505	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MCKBDDEF_01506	3.28e-110	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MCKBDDEF_01507	2.79e-313	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MCKBDDEF_01508	5.27e-239	ygaE	-	-	S	-	-	-	Membrane
MCKBDDEF_01509	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MCKBDDEF_01510	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MCKBDDEF_01511	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
MCKBDDEF_01512	7.33e-07	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MCKBDDEF_01513	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCKBDDEF_01514	2.54e-50	yfhS	-	-	-	-	-	-	-
MCKBDDEF_01515	9.18e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MCKBDDEF_01516	2.94e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MCKBDDEF_01517	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MCKBDDEF_01518	1.57e-235	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MCKBDDEF_01519	6.8e-219	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MCKBDDEF_01520	2.99e-57	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
MCKBDDEF_01521	3.85e-120	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
MCKBDDEF_01522	2.57e-59	yfhJ	-	-	S	-	-	-	WVELL protein
MCKBDDEF_01523	3.34e-214	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
MCKBDDEF_01525	2.86e-268	yfhI	-	-	EGP	-	-	-	-transporter
MCKBDDEF_01526	1.12e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MCKBDDEF_01527	3.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MCKBDDEF_01528	3.34e-212	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MCKBDDEF_01530	3.61e-34	yfhD	-	-	S	-	-	-	YfhD-like protein
MCKBDDEF_01531	1.94e-136	yfhC	-	-	C	-	-	-	nitroreductase
MCKBDDEF_01532	7.26e-209	yfhB	-	-	S	-	-	-	PhzF family
MCKBDDEF_01533	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MCKBDDEF_01534	7.97e-108	yfiV	-	-	K	-	-	-	transcriptional
MCKBDDEF_01535	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MCKBDDEF_01536	1.14e-128	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MCKBDDEF_01537	2.36e-60	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MCKBDDEF_01538	0.0	-	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MCKBDDEF_01539	7.69e-236	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MCKBDDEF_01540	1.79e-144	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MCKBDDEF_01541	5.62e-126	padR	-	-	K	-	-	-	transcriptional
MCKBDDEF_01542	7.58e-217	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MCKBDDEF_01543	4.72e-205	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MCKBDDEF_01544	5.54e-82	yfiD3	-	-	S	-	-	-	DoxX
MCKBDDEF_01545	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MCKBDDEF_01546	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MCKBDDEF_01547	1.89e-279	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
MCKBDDEF_01548	3.72e-228	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
MCKBDDEF_01549	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MCKBDDEF_01550	9.01e-178	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MCKBDDEF_01551	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MCKBDDEF_01552	6.64e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
MCKBDDEF_01553	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MCKBDDEF_01554	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MCKBDDEF_01555	5.38e-272	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MCKBDDEF_01556	1.52e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MCKBDDEF_01557	6.48e-243	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MCKBDDEF_01558	6.01e-115	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
MCKBDDEF_01559	3.47e-244	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MCKBDDEF_01560	1.64e-62	-	-	-	S	-	-	-	YfzA-like protein
MCKBDDEF_01561	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MCKBDDEF_01562	5.07e-201	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MCKBDDEF_01563	3.71e-235	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
MCKBDDEF_01565	1.09e-190	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MCKBDDEF_01566	2.8e-139	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MCKBDDEF_01567	4.57e-138	-	-	-	K	-	-	-	Two component transcriptional regulator, winged helix family
MCKBDDEF_01568	8.75e-92	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin ABC transporter permease
MCKBDDEF_01569	1.12e-103	-	-	-	S	ko:K19310	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacitracin ABC transporter permease
MCKBDDEF_01570	4.82e-184	-	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MCKBDDEF_01571	3.59e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MCKBDDEF_01572	7.99e-37	yfjT	-	-	-	-	-	-	-
MCKBDDEF_01573	2.92e-282	yfkA	-	-	S	-	-	-	YfkB-like domain
MCKBDDEF_01574	5.2e-189	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
MCKBDDEF_01575	1.62e-185	yfkD	-	-	S	-	-	-	YfkD-like protein
MCKBDDEF_01576	1.4e-237	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
MCKBDDEF_01577	4.6e-265	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_01578	6.71e-12	-	-	-	-	-	-	-	-
MCKBDDEF_01579	1.95e-185	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MCKBDDEF_01580	3.7e-70	yfkI	-	-	S	-	-	-	gas vesicle protein
MCKBDDEF_01581	1.69e-112	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MCKBDDEF_01582	1.47e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MCKBDDEF_01583	6.98e-252	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_01584	3.38e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MCKBDDEF_01585	5.86e-208	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MCKBDDEF_01586	6.43e-239	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MCKBDDEF_01587	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MCKBDDEF_01588	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MCKBDDEF_01589	1.02e-246	yibE	-	-	S	-	-	-	YibE/F-like protein
MCKBDDEF_01590	6e-167	yibF	-	-	S	-	-	-	YibE/F-like protein
MCKBDDEF_01591	2.93e-158	frp	-	-	C	-	-	-	nitroreductase
MCKBDDEF_01592	1.18e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MCKBDDEF_01593	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MCKBDDEF_01594	1.57e-313	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MCKBDDEF_01595	5.99e-50	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MCKBDDEF_01596	6.73e-51	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MCKBDDEF_01597	1.18e-103	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MCKBDDEF_01598	8.46e-84	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
MCKBDDEF_01599	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MCKBDDEF_01600	2.02e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
MCKBDDEF_01601	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MCKBDDEF_01602	9.02e-176	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MCKBDDEF_01603	1.67e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MCKBDDEF_01604	1.98e-26	yflI	-	-	-	-	-	-	-
MCKBDDEF_01605	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
MCKBDDEF_01606	2.82e-155	yflK	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_01607	4.77e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MCKBDDEF_01608	1.74e-278	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MCKBDDEF_01609	1.4e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MCKBDDEF_01610	1.65e-286	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MCKBDDEF_01611	5.87e-228	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MCKBDDEF_01612	1.38e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MCKBDDEF_01613	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MCKBDDEF_01615	7.54e-07	-	-	-	S	-	-	-	domain, Protein
MCKBDDEF_01621	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MCKBDDEF_01622	3.93e-309	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MCKBDDEF_01623	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
MCKBDDEF_01624	7.35e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
MCKBDDEF_01625	1.84e-236	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
MCKBDDEF_01626	9.42e-83	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
MCKBDDEF_01627	1.78e-264	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MCKBDDEF_01628	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MCKBDDEF_01629	5.93e-263	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
MCKBDDEF_01630	2.05e-89	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
MCKBDDEF_01631	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MCKBDDEF_01632	1.2e-265	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MCKBDDEF_01633	1.72e-214	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MCKBDDEF_01634	2.85e-169	yfmS	-	-	NT	-	-	-	chemotaxis protein
MCKBDDEF_01635	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MCKBDDEF_01636	8.39e-313	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
MCKBDDEF_01637	1.56e-277	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_01638	1.99e-238	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MCKBDDEF_01639	7.24e-285	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
MCKBDDEF_01640	1.9e-229	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MCKBDDEF_01641	3.93e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
MCKBDDEF_01642	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
MCKBDDEF_01643	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MCKBDDEF_01645	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MCKBDDEF_01646	2.28e-250	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MCKBDDEF_01647	2.19e-267	yetM	-	-	CH	-	-	-	FAD binding domain
MCKBDDEF_01648	3.45e-116	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MCKBDDEF_01649	1.8e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MCKBDDEF_01650	1.82e-73	-	-	-	H	-	-	-	riboflavin kinase activity
MCKBDDEF_01651	1.34e-31	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MCKBDDEF_01652	6.28e-197	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MCKBDDEF_01653	3.78e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCKBDDEF_01654	1.11e-72	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MCKBDDEF_01655	8.99e-157	yetF	-	-	S	-	-	-	membrane
MCKBDDEF_01656	5.92e-05	-	-	-	-	-	-	-	-
MCKBDDEF_01657	1.39e-123	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MCKBDDEF_01658	1.48e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
MCKBDDEF_01659	1.62e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
MCKBDDEF_01660	2.67e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
MCKBDDEF_01661	2.21e-138	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
MCKBDDEF_01663	3.12e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MCKBDDEF_01664	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
MCKBDDEF_01665	2.38e-101	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MCKBDDEF_01666	7.72e-68	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MCKBDDEF_01667	2.57e-60	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MCKBDDEF_01668	8.27e-67	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MCKBDDEF_01669	2.31e-80	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MCKBDDEF_01670	6.78e-176	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MCKBDDEF_01671	9.62e-203	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MCKBDDEF_01672	0.0	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MCKBDDEF_01673	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MCKBDDEF_01674	7.33e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MCKBDDEF_01675	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MCKBDDEF_01676	3.16e-197	yerO	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_01677	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCKBDDEF_01678	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MCKBDDEF_01679	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCKBDDEF_01680	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MCKBDDEF_01681	1.44e-158	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MCKBDDEF_01682	2.19e-249	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
MCKBDDEF_01683	5.54e-286	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MCKBDDEF_01684	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MCKBDDEF_01685	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MCKBDDEF_01686	8.71e-164	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MCKBDDEF_01687	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
MCKBDDEF_01688	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_01689	4.95e-246	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
MCKBDDEF_01690	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MCKBDDEF_01691	1.03e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
MCKBDDEF_01692	8.44e-300	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MCKBDDEF_01693	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MCKBDDEF_01694	9.96e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MCKBDDEF_01695	1.46e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MCKBDDEF_01696	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MCKBDDEF_01697	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MCKBDDEF_01698	1.34e-166	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MCKBDDEF_01699	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MCKBDDEF_01700	2.79e-165	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MCKBDDEF_01701	2.59e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MCKBDDEF_01702	4.56e-287	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MCKBDDEF_01703	3.78e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MCKBDDEF_01704	2.21e-38	yebG	-	-	S	-	-	-	NETI protein
MCKBDDEF_01705	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
MCKBDDEF_01707	2.16e-168	yebC	-	-	M	-	-	-	Membrane
MCKBDDEF_01708	1.23e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MCKBDDEF_01709	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
MCKBDDEF_01710	1.9e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MCKBDDEF_01711	5.95e-102	-	-	-	-	-	-	-	-
MCKBDDEF_01712	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MCKBDDEF_01713	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MCKBDDEF_01714	3.13e-274	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MCKBDDEF_01715	3.25e-225	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MCKBDDEF_01716	4.33e-315	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MCKBDDEF_01717	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MCKBDDEF_01718	2.02e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
MCKBDDEF_01720	7.08e-195	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MCKBDDEF_01721	1.6e-82	ydjM	-	-	M	-	-	-	Lytic transglycolase
MCKBDDEF_01722	1e-248	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MCKBDDEF_01723	1.87e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MCKBDDEF_01724	9.73e-194	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MCKBDDEF_01725	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
MCKBDDEF_01726	3.22e-223	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
MCKBDDEF_01727	4.16e-160	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
MCKBDDEF_01728	3.49e-226	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MCKBDDEF_01729	9.58e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MCKBDDEF_01730	3.61e-41	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
MCKBDDEF_01731	5.78e-219	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MCKBDDEF_01732	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
MCKBDDEF_01733	1.69e-255	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MCKBDDEF_01734	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
MCKBDDEF_01735	2.41e-98	yfiJ	-	-	T	-	-	-	helix_turn_helix, Lux Regulon
MCKBDDEF_01736	0.0	pbpX	-	-	V	-	-	-	Beta-lactamase
MCKBDDEF_01737	2.24e-127	-	-	-	S	-	-	-	Putative sensor
MCKBDDEF_01738	0.0	yvfT	-	-	T	-	-	-	helix_turn_helix, Lux Regulon
MCKBDDEF_01739	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MCKBDDEF_01740	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MCKBDDEF_01741	2.27e-162	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MCKBDDEF_01742	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
MCKBDDEF_01743	1.92e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MCKBDDEF_01744	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MCKBDDEF_01745	1.29e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MCKBDDEF_01746	2.84e-115	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MCKBDDEF_01747	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MCKBDDEF_01748	6.49e-245	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MCKBDDEF_01749	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MCKBDDEF_01750	1.02e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MCKBDDEF_01751	9.02e-113	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MCKBDDEF_01752	4e-233	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MCKBDDEF_01755	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MCKBDDEF_01758	0.0	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MCKBDDEF_01759	1.64e-236	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
MCKBDDEF_01760	1.7e-111	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MCKBDDEF_01761	1.04e-212	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MCKBDDEF_01762	0.0	ybeC	-	-	E	-	-	-	amino acid
MCKBDDEF_01763	3.63e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_01764	4.48e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MCKBDDEF_01765	1.73e-64	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MCKBDDEF_01766	1.23e-276	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MCKBDDEF_01767	1.55e-152	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MCKBDDEF_01768	7.17e-172	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MCKBDDEF_01769	1.29e-246	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MCKBDDEF_01770	2.49e-127	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MCKBDDEF_01772	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
MCKBDDEF_01775	1.94e-290	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MCKBDDEF_01776	2.67e-153	ydhC	-	-	K	-	-	-	FCD
MCKBDDEF_01777	9.74e-209	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Isocitrate/isopropylmalate dehydrogenase
MCKBDDEF_01778	1.34e-187	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MCKBDDEF_01779	1.35e-146	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MCKBDDEF_01780	2.1e-190	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MCKBDDEF_01781	6.89e-192	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MCKBDDEF_01782	5.09e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
MCKBDDEF_01783	3.66e-157	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MCKBDDEF_01784	7.49e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MCKBDDEF_01785	3.76e-286	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MCKBDDEF_01786	1.59e-267	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MCKBDDEF_01787	1.08e-249	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MCKBDDEF_01788	4.59e-189	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MCKBDDEF_01789	7.5e-127	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MCKBDDEF_01790	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MCKBDDEF_01791	3.41e-171	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
MCKBDDEF_01792	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
MCKBDDEF_01793	3.28e-141	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCKBDDEF_01794	1.91e-272	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_01795	1.71e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
MCKBDDEF_01796	3.35e-84	yraF	-	-	M	-	-	-	Spore coat protein
MCKBDDEF_01797	3.04e-282	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MCKBDDEF_01798	1.19e-33	yraE	-	-	-	ko:K06440	-	ko00000	-
MCKBDDEF_01799	5.09e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
MCKBDDEF_01800	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MCKBDDEF_01801	2.5e-200	ydeK	-	-	EG	-	-	-	-transporter
MCKBDDEF_01802	1.2e-132	ydeS	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_01803	3.57e-249	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MCKBDDEF_01805	3.59e-147	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_01806	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MCKBDDEF_01807	5.68e-281	nhaC_1	-	-	C	-	-	-	antiporter
MCKBDDEF_01808	4.93e-85	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MCKBDDEF_01809	9.05e-258	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
MCKBDDEF_01810	2.07e-212	-	-	-	S	-	-	-	Sodium Bile acid symporter family
MCKBDDEF_01811	1.19e-68	ydeH	-	-	-	-	-	-	-
MCKBDDEF_01812	2.9e-254	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MCKBDDEF_01814	3.29e-36	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
MCKBDDEF_01815	2.58e-37	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
MCKBDDEF_01816	1.88e-98	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
MCKBDDEF_01817	1.63e-131	yrkC	-	-	G	-	-	-	Cupin domain
MCKBDDEF_01819	9.68e-251	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
MCKBDDEF_01820	5.11e-214	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MCKBDDEF_01821	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
MCKBDDEF_01823	4.11e-82	-	-	-	G	-	-	-	Cupin domain
MCKBDDEF_01824	6.08e-102	-	-	-	S	-	-	-	DinB superfamily
MCKBDDEF_01825	1.45e-233	-	-	-	S	-	-	-	Patatin-like phospholipase
MCKBDDEF_01826	9.96e-69	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MCKBDDEF_01827	1.48e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
MCKBDDEF_01828	8.33e-156	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MCKBDDEF_01829	1.25e-166	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MCKBDDEF_01830	6.46e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
MCKBDDEF_01831	1.6e-251	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
MCKBDDEF_01832	3.64e-129	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
MCKBDDEF_01833	1.42e-76	-	-	-	P	-	-	-	Rhodanese Homology Domain
MCKBDDEF_01834	9.32e-107	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
MCKBDDEF_01835	1.53e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_01836	8.42e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MCKBDDEF_01837	3.87e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MCKBDDEF_01838	1.97e-241	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MCKBDDEF_01839	2.22e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MCKBDDEF_01840	4.07e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_01841	1.59e-85	-	-	-	S	-	-	-	YjbR
MCKBDDEF_01842	2.13e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MCKBDDEF_01843	1.41e-93	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
MCKBDDEF_01844	1.04e-65	ohrR	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_01845	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
MCKBDDEF_01847	3.49e-175	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MCKBDDEF_01848	3.81e-56	-	-	-	-	-	-	-	-
MCKBDDEF_01850	9.77e-150	-	-	-	S	-	-	-	ATPase (AAA superfamily
MCKBDDEF_01859	2.88e-74	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MCKBDDEF_01860	1.78e-21	-	-	-	-	-	-	-	-
MCKBDDEF_01861	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MCKBDDEF_01862	5.75e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MCKBDDEF_01863	1.61e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCKBDDEF_01864	7.1e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MCKBDDEF_01865	9.77e-71	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MCKBDDEF_01866	1.25e-241	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MCKBDDEF_01867	1.73e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MCKBDDEF_01868	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MCKBDDEF_01869	1.05e-186	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MCKBDDEF_01870	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MCKBDDEF_01871	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MCKBDDEF_01872	3.83e-277	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MCKBDDEF_01873	1.29e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MCKBDDEF_01874	1.09e-75	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MCKBDDEF_01875	2.96e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MCKBDDEF_01876	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MCKBDDEF_01877	1.96e-108	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MCKBDDEF_01878	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MCKBDDEF_01879	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MCKBDDEF_01880	2.52e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MCKBDDEF_01881	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
MCKBDDEF_01882	6.66e-159	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MCKBDDEF_01883	9.35e-14	-	-	-	S	-	-	-	Fur-regulated basic protein A
MCKBDDEF_01884	1.13e-15	-	-	-	S	-	-	-	Fur-regulated basic protein B
MCKBDDEF_01885	2.15e-261	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MCKBDDEF_01886	5.4e-69	ydbL	-	-	-	-	-	-	-
MCKBDDEF_01887	3.47e-167	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MCKBDDEF_01888	3.37e-221	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_01889	8.61e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
MCKBDDEF_01890	1.59e-286	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCKBDDEF_01891	3.67e-153	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MCKBDDEF_01892	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MCKBDDEF_01893	2.58e-253	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MCKBDDEF_01894	1.92e-198	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
MCKBDDEF_01895	1.01e-79	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
MCKBDDEF_01896	2.65e-78	ydbB	-	-	G	-	-	-	Cupin domain
MCKBDDEF_01897	2.34e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MCKBDDEF_01898	1.09e-181	ydbA	-	-	P	-	-	-	EcsC protein family
MCKBDDEF_01899	2.87e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
MCKBDDEF_01900	5.32e-94	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
MCKBDDEF_01901	1.95e-45	ydaT	-	-	-	-	-	-	-
MCKBDDEF_01903	1.08e-287	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MCKBDDEF_01904	7.45e-54	-	-	-	-	-	-	-	-
MCKBDDEF_01905	1.65e-127	-	-	-	-	-	-	-	-
MCKBDDEF_01906	2.53e-114	-	-	-	-	-	-	-	-
MCKBDDEF_01908	2.69e-12	-	-	-	-	-	-	-	-
MCKBDDEF_01910	1.65e-267	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MCKBDDEF_01912	2.27e-101	-	-	-	-	-	-	-	-
MCKBDDEF_01913	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MCKBDDEF_01914	1.04e-74	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MCKBDDEF_01915	0.0	ydaO	-	-	E	-	-	-	amino acid
MCKBDDEF_01916	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
MCKBDDEF_01917	2.16e-301	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MCKBDDEF_01918	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
MCKBDDEF_01919	2.67e-189	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
MCKBDDEF_01920	1.34e-256	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MCKBDDEF_01921	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MCKBDDEF_01922	3.25e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MCKBDDEF_01923	6.54e-63	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MCKBDDEF_01924	2.54e-176	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MCKBDDEF_01925	1.83e-101	ydaG	-	-	S	-	-	-	general stress protein
MCKBDDEF_01926	1.3e-145	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MCKBDDEF_01927	7.9e-125	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MCKBDDEF_01928	9.37e-208	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCKBDDEF_01929	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
MCKBDDEF_01930	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MCKBDDEF_01931	2.57e-221	ycsN	-	-	S	-	-	-	Oxidoreductase
MCKBDDEF_01932	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MCKBDDEF_01933	5.95e-75	yczJ	-	-	S	-	-	-	biosynthesis
MCKBDDEF_01935	2.23e-149	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MCKBDDEF_01936	2.69e-166	kipR	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_01937	1.03e-241	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MCKBDDEF_01938	2.7e-174	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MCKBDDEF_01939	1.4e-191	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MCKBDDEF_01940	2.66e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MCKBDDEF_01941	8.34e-179	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MCKBDDEF_01942	1.1e-176	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MCKBDDEF_01944	1.38e-85	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MCKBDDEF_01945	1.21e-265	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MCKBDDEF_01946	4.11e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MCKBDDEF_01947	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MCKBDDEF_01948	1.59e-71	-	-	-	-	-	-	-	-
MCKBDDEF_01949	4.26e-138	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MCKBDDEF_01950	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
MCKBDDEF_01951	2.05e-131	ycnI	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_01952	4.85e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCKBDDEF_01953	8.27e-191	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
MCKBDDEF_01954	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MCKBDDEF_01955	2.17e-287	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MCKBDDEF_01956	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MCKBDDEF_01957	2.76e-70	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MCKBDDEF_01958	8.02e-59	ycnE	-	-	S	-	-	-	Monooxygenase
MCKBDDEF_01959	1.97e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
MCKBDDEF_01960	4.47e-197	ycnC	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_01961	4.87e-314	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MCKBDDEF_01962	3.24e-222	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MCKBDDEF_01963	4.63e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_01964	1.64e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCKBDDEF_01965	3.85e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCKBDDEF_01966	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MCKBDDEF_01968	1.2e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MCKBDDEF_01969	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
MCKBDDEF_01970	2.6e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_01971	6.53e-309	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
MCKBDDEF_01972	1.62e-158	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MCKBDDEF_01973	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
MCKBDDEF_01974	2.3e-275	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MCKBDDEF_01975	2.28e-169	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_01976	1.49e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MCKBDDEF_01977	5.21e-182	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MCKBDDEF_01978	4.43e-120	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCKBDDEF_01979	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCKBDDEF_01980	1.86e-248	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
MCKBDDEF_01981	2.82e-300	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
MCKBDDEF_01982	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MCKBDDEF_01984	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
MCKBDDEF_01985	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
MCKBDDEF_01986	6.81e-100	yclD	-	-	-	-	-	-	-
MCKBDDEF_01987	2.83e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
MCKBDDEF_01988	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MCKBDDEF_01989	1.4e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MCKBDDEF_01990	5.96e-206	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
MCKBDDEF_01991	8.63e-121	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MCKBDDEF_01992	3.53e-153	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MCKBDDEF_01993	3.24e-168	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MCKBDDEF_01994	3.11e-144	yczE	-	-	S	ko:K07149	-	ko00000	membrane
MCKBDDEF_01995	1.3e-167	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
MCKBDDEF_01996	5.72e-316	-	-	-	E	-	-	-	Aminotransferase class I and II
MCKBDDEF_01997	3.56e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
MCKBDDEF_01998	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MCKBDDEF_01999	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_02000	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_02001	4.1e-84	hxlR	-	-	K	-	-	-	transcriptional
MCKBDDEF_02002	5.21e-138	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MCKBDDEF_02003	1.22e-121	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MCKBDDEF_02004	1.88e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MCKBDDEF_02005	6.79e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
MCKBDDEF_02006	1.37e-43	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MCKBDDEF_02007	9.5e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
MCKBDDEF_02008	2.2e-95	yckC	-	-	S	-	-	-	membrane
MCKBDDEF_02009	7.17e-281	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MCKBDDEF_02010	1.73e-290	yciC	-	-	S	-	-	-	GTPases (G3E family)
MCKBDDEF_02011	4.05e-285	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MCKBDDEF_02012	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
MCKBDDEF_02013	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MCKBDDEF_02014	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MCKBDDEF_02015	3.45e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MCKBDDEF_02016	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MCKBDDEF_02017	3.33e-242	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MCKBDDEF_02018	1.43e-290	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MCKBDDEF_02019	6.34e-311	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MCKBDDEF_02020	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MCKBDDEF_02021	9.61e-217	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MCKBDDEF_02022	8.94e-183	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
MCKBDDEF_02023	3.29e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MCKBDDEF_02024	1.01e-134	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MCKBDDEF_02025	2.75e-287	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_02026	5.46e-188	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
MCKBDDEF_02027	2.44e-141	tmrB	-	-	S	-	-	-	AAA domain
MCKBDDEF_02028	2.77e-06	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MCKBDDEF_02029	1.29e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MCKBDDEF_02030	3.22e-146	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
MCKBDDEF_02031	1.15e-314	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MCKBDDEF_02032	4.19e-192	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MCKBDDEF_02033	1.11e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
MCKBDDEF_02034	2.82e-100	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MCKBDDEF_02035	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
MCKBDDEF_02036	6.6e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MCKBDDEF_02037	5.7e-32	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MCKBDDEF_02038	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MCKBDDEF_02039	4.41e-106	ycgB	-	-	-	-	-	-	-
MCKBDDEF_02040	8.03e-294	ycgA	-	-	S	-	-	-	Membrane
MCKBDDEF_02041	4.59e-270	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
MCKBDDEF_02042	2.85e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MCKBDDEF_02043	2.45e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MCKBDDEF_02044	1.28e-292	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MCKBDDEF_02045	2.59e-276	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
MCKBDDEF_02046	4.74e-246	yceH	-	-	P	-	-	-	Belongs to the TelA family
MCKBDDEF_02047	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MCKBDDEF_02048	2.12e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
MCKBDDEF_02049	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MCKBDDEF_02050	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MCKBDDEF_02051	4.06e-140	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MCKBDDEF_02052	6.94e-237	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCKBDDEF_02053	1.19e-174	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MCKBDDEF_02054	5.69e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MCKBDDEF_02055	3.64e-214	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MCKBDDEF_02056	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MCKBDDEF_02057	1.23e-178	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MCKBDDEF_02058	5.77e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MCKBDDEF_02059	1.79e-121	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MCKBDDEF_02060	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MCKBDDEF_02061	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MCKBDDEF_02062	6.27e-224	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
MCKBDDEF_02063	9e-129	yccK	-	-	C	-	-	-	Aldo keto reductase
MCKBDDEF_02064	6.12e-69	yccK	-	-	C	-	-	-	Aldo keto reductase
MCKBDDEF_02065	9.7e-252	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MCKBDDEF_02066	3.29e-147	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MCKBDDEF_02067	1.8e-250	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MCKBDDEF_02068	1.04e-128	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MCKBDDEF_02069	1.68e-311	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MCKBDDEF_02070	1.92e-263	ycbU	-	-	E	-	-	-	Selenocysteine lyase
MCKBDDEF_02071	4.68e-152	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MCKBDDEF_02072	4.24e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MCKBDDEF_02073	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MCKBDDEF_02074	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
MCKBDDEF_02075	1.44e-99	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MCKBDDEF_02076	1.63e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MCKBDDEF_02077	2.56e-72	ydfQ	-	-	CO	-	-	-	Thioredoxin
MCKBDDEF_02078	1.14e-83	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
MCKBDDEF_02079	2.06e-233	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MCKBDDEF_02080	9.49e-143	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
MCKBDDEF_02081	2.12e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MCKBDDEF_02082	4.85e-35	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
MCKBDDEF_02083	2.46e-08	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
MCKBDDEF_02084	5.81e-221	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
MCKBDDEF_02085	1.26e-278	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_02086	1.11e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MCKBDDEF_02087	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MCKBDDEF_02088	1.69e-229	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
MCKBDDEF_02089	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MCKBDDEF_02090	8.33e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MCKBDDEF_02091	1.17e-271	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCKBDDEF_02092	5.76e-245	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MCKBDDEF_02093	8.67e-55	ybfN	-	-	-	-	-	-	-
MCKBDDEF_02094	7.49e-195	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MCKBDDEF_02095	4.26e-113	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MCKBDDEF_02096	1.56e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MCKBDDEF_02097	1.87e-270	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MCKBDDEF_02098	8.67e-255	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MCKBDDEF_02099	1.14e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MCKBDDEF_02100	2.1e-71	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
MCKBDDEF_02101	4.73e-176	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MCKBDDEF_02103	8.96e-67	-	-	-	S	ko:K19169	-	ko00000,ko02048	DNA-sulfur modification-associated
MCKBDDEF_02104	1.14e-25	-	-	-	S	ko:K19169	-	ko00000,ko02048	DNA-sulfur modification-associated
MCKBDDEF_02105	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MCKBDDEF_02107	1.66e-266	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
MCKBDDEF_02108	5.8e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MCKBDDEF_02109	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
MCKBDDEF_02110	8.18e-211	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
MCKBDDEF_02111	6.28e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MCKBDDEF_02113	5.3e-62	-	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MCKBDDEF_02114	0.0	ybeC	-	-	E	-	-	-	amino acid
MCKBDDEF_02115	7.84e-55	ybyB	-	-	-	-	-	-	-
MCKBDDEF_02116	4.16e-143	yqeB	-	-	-	-	-	-	-
MCKBDDEF_02117	1.01e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
MCKBDDEF_02118	6.08e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
MCKBDDEF_02119	2.34e-35	-	-	-	-	-	-	-	-
MCKBDDEF_02120	1.32e-252	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MCKBDDEF_02121	3.18e-263	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MCKBDDEF_02122	6.21e-214	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MCKBDDEF_02123	2.04e-141	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
MCKBDDEF_02124	2.38e-253	-	-	-	T	-	-	-	COG4585 Signal transduction histidine kinase
MCKBDDEF_02125	1.07e-118	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MCKBDDEF_02126	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MCKBDDEF_02128	5.62e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MCKBDDEF_02129	9.9e-68	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
MCKBDDEF_02130	6.05e-135	yxaC	-	-	M	-	-	-	effector of murein hydrolase
MCKBDDEF_02131	1.03e-206	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
MCKBDDEF_02133	4.5e-15	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MCKBDDEF_02134	0.0	-	-	-	V	ko:K02004,ko:K11632	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MCKBDDEF_02135	6.57e-176	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_02136	2.32e-235	-	-	-	T	ko:K19168	-	ko00000,ko02048	Histidine kinase
MCKBDDEF_02137	8.72e-163	-	-	-	T	ko:K11630	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_02138	1.42e-138	-	-	-	S	-	-	-	ABC-2 family transporter protein
MCKBDDEF_02139	2.14e-199	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MCKBDDEF_02140	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MCKBDDEF_02141	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MCKBDDEF_02142	7.18e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_02143	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MCKBDDEF_02144	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MCKBDDEF_02145	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MCKBDDEF_02151	1.93e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
MCKBDDEF_02152	7.13e-110	ybbJ	-	-	J	-	-	-	acetyltransferase
MCKBDDEF_02153	3.84e-207	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MCKBDDEF_02154	5.86e-310	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MCKBDDEF_02155	2.56e-308	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MCKBDDEF_02156	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MCKBDDEF_02157	2.61e-299	ybbC	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_02158	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MCKBDDEF_02159	1.21e-219	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MCKBDDEF_02160	1.8e-225	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCKBDDEF_02161	1.43e-229	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCKBDDEF_02162	1.35e-143	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
MCKBDDEF_02163	1.08e-222	ybaS	-	-	S	-	-	-	Na -dependent transporter
MCKBDDEF_02164	2.62e-286	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MCKBDDEF_02165	3.13e-253	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MCKBDDEF_02166	7.74e-231	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
MCKBDDEF_02167	1.22e-311	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MCKBDDEF_02168	3.31e-281	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MCKBDDEF_02169	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MCKBDDEF_02175	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MCKBDDEF_02176	6.38e-183	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MCKBDDEF_02177	1.25e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MCKBDDEF_02178	1.95e-102	gerD	-	-	-	ko:K06294	-	ko00000	-
MCKBDDEF_02179	9e-254	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MCKBDDEF_02180	2.31e-172	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MCKBDDEF_02181	9.25e-103	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MCKBDDEF_02182	9.4e-110	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
MCKBDDEF_02183	1.76e-185	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
MCKBDDEF_02184	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MCKBDDEF_02185	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MCKBDDEF_02186	3.56e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MCKBDDEF_02187	7.93e-178	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCKBDDEF_02188	2.09e-191	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCKBDDEF_02189	1.45e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCKBDDEF_02190	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MCKBDDEF_02191	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCKBDDEF_02192	4.61e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MCKBDDEF_02193	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MCKBDDEF_02194	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MCKBDDEF_02195	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MCKBDDEF_02196	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MCKBDDEF_02197	4.34e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MCKBDDEF_02198	1.34e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MCKBDDEF_02199	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MCKBDDEF_02200	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MCKBDDEF_02201	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MCKBDDEF_02202	8.29e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MCKBDDEF_02203	3.14e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MCKBDDEF_02204	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MCKBDDEF_02205	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCKBDDEF_02206	5.43e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MCKBDDEF_02207	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MCKBDDEF_02208	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MCKBDDEF_02209	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MCKBDDEF_02210	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MCKBDDEF_02211	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MCKBDDEF_02212	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MCKBDDEF_02213	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MCKBDDEF_02214	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MCKBDDEF_02215	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MCKBDDEF_02216	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MCKBDDEF_02217	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MCKBDDEF_02218	1.77e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MCKBDDEF_02219	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MCKBDDEF_02220	2.33e-239	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
MCKBDDEF_02221	2.35e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MCKBDDEF_02222	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MCKBDDEF_02223	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MCKBDDEF_02224	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MCKBDDEF_02225	5.94e-46	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MCKBDDEF_02226	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCKBDDEF_02227	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCKBDDEF_02228	1.2e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MCKBDDEF_02229	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MCKBDDEF_02230	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MCKBDDEF_02231	8.66e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MCKBDDEF_02232	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MCKBDDEF_02233	1.28e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MCKBDDEF_02234	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MCKBDDEF_02235	1.39e-150	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MCKBDDEF_02236	4.03e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MCKBDDEF_02237	1.01e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCKBDDEF_02238	4.11e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MCKBDDEF_02239	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MCKBDDEF_02240	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MCKBDDEF_02241	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MCKBDDEF_02242	3.02e-111	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MCKBDDEF_02243	2.38e-158	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MCKBDDEF_02244	8.6e-251	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MCKBDDEF_02245	7.66e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MCKBDDEF_02246	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MCKBDDEF_02247	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MCKBDDEF_02248	1.63e-258	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MCKBDDEF_02249	1.14e-83	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
MCKBDDEF_02250	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MCKBDDEF_02251	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MCKBDDEF_02261	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MCKBDDEF_02262	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MCKBDDEF_02263	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MCKBDDEF_02264	8.67e-40	yazB	-	-	K	-	-	-	transcriptional
MCKBDDEF_02265	3.34e-117	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MCKBDDEF_02266	1.13e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MCKBDDEF_02267	2.24e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MCKBDDEF_02268	2.83e-206	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MCKBDDEF_02269	2.97e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MCKBDDEF_02270	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MCKBDDEF_02271	2.09e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MCKBDDEF_02272	1.16e-193	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
MCKBDDEF_02273	1.3e-205	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MCKBDDEF_02274	8.14e-178	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MCKBDDEF_02275	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MCKBDDEF_02276	1.05e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MCKBDDEF_02277	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MCKBDDEF_02278	3.3e-236	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MCKBDDEF_02279	5.38e-166	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MCKBDDEF_02280	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MCKBDDEF_02283	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MCKBDDEF_02284	6.94e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MCKBDDEF_02285	7.53e-118	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MCKBDDEF_02286	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
MCKBDDEF_02287	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MCKBDDEF_02288	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MCKBDDEF_02289	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCKBDDEF_02290	8.02e-119	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MCKBDDEF_02291	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MCKBDDEF_02292	1.1e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MCKBDDEF_02293	1.74e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MCKBDDEF_02294	3.57e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MCKBDDEF_02295	2.47e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MCKBDDEF_02296	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MCKBDDEF_02297	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MCKBDDEF_02298	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MCKBDDEF_02299	5.67e-197	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MCKBDDEF_02300	2.73e-206	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MCKBDDEF_02301	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MCKBDDEF_02302	3.08e-52	veg	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_02303	6.71e-208	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MCKBDDEF_02304	2.07e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MCKBDDEF_02305	7.62e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MCKBDDEF_02306	3.23e-306	yabE	-	-	T	-	-	-	protein conserved in bacteria
MCKBDDEF_02307	1.02e-182	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MCKBDDEF_02308	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MCKBDDEF_02309	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MCKBDDEF_02310	1.65e-209	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MCKBDDEF_02311	6.96e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MCKBDDEF_02312	3.99e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MCKBDDEF_02313	3.08e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MCKBDDEF_02314	9e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MCKBDDEF_02315	1.9e-233	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MCKBDDEF_02316	2.98e-94	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MCKBDDEF_02317	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_02318	1.9e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MCKBDDEF_02319	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MCKBDDEF_02320	2.32e-242	yaaN	-	-	P	-	-	-	Belongs to the TelA family
MCKBDDEF_02321	7.19e-137	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MCKBDDEF_02322	4.46e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
MCKBDDEF_02325	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MCKBDDEF_02326	6.44e-50	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
MCKBDDEF_02327	5.4e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MCKBDDEF_02328	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MCKBDDEF_02329	9.8e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MCKBDDEF_02330	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MCKBDDEF_02331	2.48e-111	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MCKBDDEF_02332	1.44e-128	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MCKBDDEF_02333	5.59e-275	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MCKBDDEF_02334	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MCKBDDEF_02335	7.51e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MCKBDDEF_02337	1.9e-257	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MCKBDDEF_02338	1.3e-284	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MCKBDDEF_02339	2.86e-139	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MCKBDDEF_02340	1.29e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MCKBDDEF_02341	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MCKBDDEF_02342	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MCKBDDEF_02343	8.24e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
MCKBDDEF_02346	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MCKBDDEF_02347	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCKBDDEF_02348	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCKBDDEF_02349	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MCKBDDEF_02350	3.2e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MCKBDDEF_02351	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MCKBDDEF_02352	8.47e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MCKBDDEF_02353	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MCKBDDEF_02355	1.99e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MCKBDDEF_02356	2.12e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MCKBDDEF_02357	7.7e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MCKBDDEF_02358	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MCKBDDEF_02359	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MCKBDDEF_02360	2.29e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MCKBDDEF_02361	1.1e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MCKBDDEF_02362	1.23e-172	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MCKBDDEF_02363	8.27e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MCKBDDEF_02364	8.14e-143	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MCKBDDEF_02365	2.62e-105	yhhY	-	-	K	-	-	-	FR47-like protein
MCKBDDEF_02366	4.77e-225	yyaD	-	-	S	-	-	-	Membrane
MCKBDDEF_02367	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_02368	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MCKBDDEF_02369	5.42e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MCKBDDEF_02370	2.9e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MCKBDDEF_02371	1.37e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MCKBDDEF_02372	4.51e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MCKBDDEF_02373	3.63e-136	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MCKBDDEF_02374	3.38e-128	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MCKBDDEF_02375	3.29e-184	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MCKBDDEF_02376	6.62e-230	ccpB	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02377	4.88e-88	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCKBDDEF_02378	1.88e-316	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
MCKBDDEF_02379	2.84e-208	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MCKBDDEF_02380	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MCKBDDEF_02383	4.54e-91	ynaF	-	-	-	-	-	-	-
MCKBDDEF_02384	1.02e-106	-	-	-	-	-	-	-	-
MCKBDDEF_02385	1.53e-36	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MCKBDDEF_02386	6.35e-167	-	-	-	EG	-	-	-	EamA-like transporter family
MCKBDDEF_02387	1.29e-313	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MCKBDDEF_02388	2.35e-176	bdh	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MCKBDDEF_02389	4.21e-212	-	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02390	4.76e-87	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MCKBDDEF_02391	3.34e-211	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
MCKBDDEF_02392	1.49e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MCKBDDEF_02393	1.3e-99	yybA	-	-	K	-	-	-	transcriptional
MCKBDDEF_02394	1.48e-191	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MCKBDDEF_02395	2.77e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MCKBDDEF_02396	1.62e-145	ydgI	-	-	C	-	-	-	nitroreductase
MCKBDDEF_02397	1.12e-73	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MCKBDDEF_02398	5.87e-201	-	-	-	G	-	-	-	Major Facilitator Superfamily
MCKBDDEF_02399	2.63e-115	-	-	-	S	-	-	-	PFAM DinB family protein
MCKBDDEF_02400	3.82e-149	-	-	-	K	-	-	-	FCD domain
MCKBDDEF_02401	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MCKBDDEF_02402	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MCKBDDEF_02403	1.02e-197	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MCKBDDEF_02404	2.95e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MCKBDDEF_02405	4.56e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02406	3.33e-111	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MCKBDDEF_02408	1.95e-201	yybS	-	-	S	-	-	-	membrane
MCKBDDEF_02409	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MCKBDDEF_02410	1.58e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MCKBDDEF_02411	1.7e-157	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
MCKBDDEF_02412	2.15e-157	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
MCKBDDEF_02413	5.98e-302	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MCKBDDEF_02414	6.57e-297	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
MCKBDDEF_02415	6.38e-259	-	-	-	S	-	-	-	Ecdysteroid kinase
MCKBDDEF_02416	1.79e-305	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MCKBDDEF_02417	5.12e-25	yycC	-	-	K	-	-	-	YycC-like protein
MCKBDDEF_02419	7.68e-39	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MCKBDDEF_02420	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MCKBDDEF_02421	1.57e-94	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCKBDDEF_02422	1.06e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MCKBDDEF_02427	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_02428	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_02429	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_02430	2.81e-194	yycI	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_02431	5.69e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MCKBDDEF_02432	1.63e-278	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MCKBDDEF_02433	2.5e-14	phoP1	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_02434	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MCKBDDEF_02435	2.31e-243	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
MCKBDDEF_02436	0.0	-	-	-	-	-	-	-	-
MCKBDDEF_02437	4.27e-257	-	-	-	S	-	-	-	Major Facilitator Superfamily
MCKBDDEF_02438	0.0	-	-	-	S	-	-	-	ABC transporter
MCKBDDEF_02439	6.44e-189	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
MCKBDDEF_02440	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MCKBDDEF_02441	9.38e-58	sdpR	-	-	K	-	-	-	transcriptional
MCKBDDEF_02442	1.99e-89	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MCKBDDEF_02443	1.95e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MCKBDDEF_02444	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MCKBDDEF_02445	1.86e-212	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MCKBDDEF_02446	9.49e-262	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MCKBDDEF_02448	2.92e-113	yycN	-	-	K	-	-	-	Acetyltransferase
MCKBDDEF_02449	6.14e-233	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MCKBDDEF_02450	6.82e-171	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MCKBDDEF_02451	2.21e-275	yycP	-	-	-	-	-	-	-
MCKBDDEF_02454	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MCKBDDEF_02455	3.12e-116	-	-	-	K	-	-	-	NAD+ binding
MCKBDDEF_02456	8.08e-97	-	-	-	F	-	-	-	5-carbamoylmethyl uridine residue modification
MCKBDDEF_02457	0.0	-	-	-	L	-	-	-	AAA domain
MCKBDDEF_02458	5.2e-26	-	-	-	-	-	-	-	-
MCKBDDEF_02459	9.35e-233	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MCKBDDEF_02460	1.03e-237	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MCKBDDEF_02461	3.73e-119	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MCKBDDEF_02462	3.46e-77	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MCKBDDEF_02463	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MCKBDDEF_02464	1.91e-197	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MCKBDDEF_02465	4.92e-110	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MCKBDDEF_02466	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
MCKBDDEF_02467	1.51e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MCKBDDEF_02468	3.95e-292	-	-	-	S	-	-	-	Fic/DOC family
MCKBDDEF_02469	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
MCKBDDEF_02470	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
MCKBDDEF_02471	2.59e-160	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
MCKBDDEF_02472	7.8e-97	yxaI	-	-	S	-	-	-	membrane protein domain
MCKBDDEF_02473	7.67e-256	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MCKBDDEF_02474	1.21e-67	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MCKBDDEF_02475	2.5e-85	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
MCKBDDEF_02476	1.58e-187	yxaL	-	-	S	-	-	-	PQQ-like domain
MCKBDDEF_02477	0.0	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MCKBDDEF_02478	5.42e-275	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MCKBDDEF_02479	1.01e-254	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MCKBDDEF_02480	4.12e-255	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_02481	3.72e-132	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCKBDDEF_02482	5.9e-193	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MCKBDDEF_02484	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MCKBDDEF_02485	4.5e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MCKBDDEF_02486	3.94e-221	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MCKBDDEF_02487	6.09e-175	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MCKBDDEF_02488	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MCKBDDEF_02489	3.45e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MCKBDDEF_02490	5.42e-229	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MCKBDDEF_02491	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MCKBDDEF_02492	4.62e-223	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MCKBDDEF_02493	1.23e-292	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MCKBDDEF_02494	6.3e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MCKBDDEF_02495	6.24e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
MCKBDDEF_02496	2.68e-192	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MCKBDDEF_02497	1.35e-202	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MCKBDDEF_02498	1.05e-167	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MCKBDDEF_02499	9.21e-166	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	permease
MCKBDDEF_02500	7.54e-211	-	-	-	V	ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_02501	1.51e-174	yvrH	-	-	T	-	-	-	Transcriptional regulator
MCKBDDEF_02502	0.0	-	-	-	T	-	-	-	Histidine kinase
MCKBDDEF_02503	1.09e-157	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_02504	4.59e-223	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_02505	6.61e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_02506	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MCKBDDEF_02507	4.9e-76	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MCKBDDEF_02508	1.61e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MCKBDDEF_02509	2.27e-08	-	-	-	L	-	-	-	Helix-hairpin-helix motif
MCKBDDEF_02510	6.89e-08	yxeD	-	-	-	-	-	-	-
MCKBDDEF_02511	9.43e-34	yxeE	-	-	-	-	-	-	-
MCKBDDEF_02514	2.32e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MCKBDDEF_02515	1.12e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MCKBDDEF_02516	1.17e-144	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MCKBDDEF_02517	4.04e-265	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MCKBDDEF_02518	1.1e-296	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MCKBDDEF_02519	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MCKBDDEF_02520	1.32e-222	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MCKBDDEF_02521	3.7e-298	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
MCKBDDEF_02522	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MCKBDDEF_02523	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
MCKBDDEF_02524	2.45e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MCKBDDEF_02525	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MCKBDDEF_02527	4.36e-225	-	-	-	L	-	-	-	AlwI restriction endonuclease
MCKBDDEF_02528	3.9e-232	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
MCKBDDEF_02529	5.59e-58	-	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MCKBDDEF_02530	1.86e-18	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
MCKBDDEF_02531	5.71e-130	-	-	-	L	-	-	-	Replication protein
MCKBDDEF_02532	4.69e-39	-	-	-	-	-	-	-	-
MCKBDDEF_02534	7.64e-53	-	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02537	1.41e-93	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
MCKBDDEF_02538	8.44e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MCKBDDEF_02539	1.05e-254	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MCKBDDEF_02540	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MCKBDDEF_02541	1e-279	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MCKBDDEF_02542	1.91e-183	bglS	-	-	M	-	-	-	licheninase activity
MCKBDDEF_02543	1.35e-282	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MCKBDDEF_02544	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MCKBDDEF_02545	2.68e-67	yxiS	-	-	-	-	-	-	-
MCKBDDEF_02546	8.8e-125	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
MCKBDDEF_02547	9.51e-267	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MCKBDDEF_02548	1.83e-163	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MCKBDDEF_02549	6.59e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MCKBDDEF_02550	6.11e-111	yxjI	-	-	S	-	-	-	LURP-one-related
MCKBDDEF_02553	6.94e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MCKBDDEF_02554	2.28e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MCKBDDEF_02555	2.68e-120	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MCKBDDEF_02556	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MCKBDDEF_02557	2.63e-208	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MCKBDDEF_02558	2.62e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_02559	8.1e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MCKBDDEF_02560	3.19e-287	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
MCKBDDEF_02561	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MCKBDDEF_02562	1.12e-241	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
MCKBDDEF_02563	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
MCKBDDEF_02564	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
MCKBDDEF_02565	3.07e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MCKBDDEF_02566	3.43e-77	-	-	-	S	-	-	-	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MCKBDDEF_02567	5.75e-131	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MCKBDDEF_02568	0.00047	-	-	-	T	-	-	-	helix_turn_helix, Lux Regulon
MCKBDDEF_02569	7.05e-24	ypdB	-	-	KT	ko:K02477,ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MCKBDDEF_02572	1.81e-127	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MCKBDDEF_02574	8.52e-314	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MCKBDDEF_02575	2.26e-245	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MCKBDDEF_02576	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MCKBDDEF_02577	8.82e-266	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MCKBDDEF_02578	1.58e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MCKBDDEF_02579	1.27e-29	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MCKBDDEF_02580	1.93e-139	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MCKBDDEF_02581	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MCKBDDEF_02582	1.41e-302	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCKBDDEF_02583	3.22e-65	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MCKBDDEF_02584	1.18e-66	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MCKBDDEF_02585	6.3e-291	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MCKBDDEF_02586	6.17e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MCKBDDEF_02587	7.58e-213	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MCKBDDEF_02588	1.38e-230	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCKBDDEF_02589	4.69e-220	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCKBDDEF_02590	1.08e-143	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MCKBDDEF_02591	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MCKBDDEF_02592	4.46e-66	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
MCKBDDEF_02593	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCKBDDEF_02594	1.18e-67	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MCKBDDEF_02595	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MCKBDDEF_02596	1.35e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MCKBDDEF_02597	4.21e-287	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MCKBDDEF_02598	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_02599	2.56e-293	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
MCKBDDEF_02600	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_02601	7.08e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MCKBDDEF_02602	7.57e-215	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MCKBDDEF_02603	1.85e-151	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MCKBDDEF_02604	3.64e-208	gspA	-	-	M	-	-	-	General stress
MCKBDDEF_02605	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MCKBDDEF_02606	2.71e-314	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCKBDDEF_02607	1.06e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
MCKBDDEF_02608	5.11e-285	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MCKBDDEF_02609	9.24e-217	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
MCKBDDEF_02610	1.01e-174	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
MCKBDDEF_02611	9.1e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
MCKBDDEF_02612	6.47e-144	ywbG	-	-	M	-	-	-	effector of murein hydrolase
MCKBDDEF_02613	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MCKBDDEF_02614	4.83e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02615	1.02e-172	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MCKBDDEF_02616	5.8e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MCKBDDEF_02617	5.15e-308	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
MCKBDDEF_02618	3.09e-145	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MCKBDDEF_02619	1.58e-168	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
MCKBDDEF_02620	7.2e-166	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
MCKBDDEF_02622	6.43e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MCKBDDEF_02623	2e-80	gtcA	-	-	S	-	-	-	GtrA-like protein
MCKBDDEF_02624	4.22e-288	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MCKBDDEF_02625	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MCKBDDEF_02626	5.74e-48	ydaS	-	-	S	-	-	-	membrane
MCKBDDEF_02627	3.14e-228	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MCKBDDEF_02628	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MCKBDDEF_02629	4.91e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MCKBDDEF_02630	6.76e-84	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MCKBDDEF_02631	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MCKBDDEF_02632	1.24e-99	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
MCKBDDEF_02633	7.63e-271	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MCKBDDEF_02634	1.14e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
MCKBDDEF_02635	1.34e-235	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCKBDDEF_02636	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MCKBDDEF_02638	4.68e-196	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MCKBDDEF_02639	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MCKBDDEF_02640	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MCKBDDEF_02641	3.52e-26	ywdA	-	-	-	-	-	-	-
MCKBDDEF_02642	3.39e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MCKBDDEF_02643	1.32e-74	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
MCKBDDEF_02645	7.67e-85	ywdD	-	-	-	-	-	-	-
MCKBDDEF_02647	3.29e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
MCKBDDEF_02648	7.22e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MCKBDDEF_02649	1.06e-60	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
MCKBDDEF_02650	5.38e-291	ywdJ	-	-	F	-	-	-	Xanthine uracil
MCKBDDEF_02651	2.17e-76	ywdK	-	-	S	-	-	-	small membrane protein
MCKBDDEF_02652	6.51e-88	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MCKBDDEF_02653	5.24e-183	spsA	-	-	M	-	-	-	Spore Coat
MCKBDDEF_02654	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
MCKBDDEF_02655	3.57e-282	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MCKBDDEF_02656	6.71e-206	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
MCKBDDEF_02657	7.09e-274	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
MCKBDDEF_02658	7.11e-172	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
MCKBDDEF_02659	5.91e-235	spsG	-	-	M	-	-	-	Spore Coat
MCKBDDEF_02660	1.63e-176	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MCKBDDEF_02661	6.14e-232	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MCKBDDEF_02662	4.55e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MCKBDDEF_02663	1.15e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
MCKBDDEF_02664	1.32e-221	bcrA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_02665	1.48e-153	-	-	-	S	-	-	-	ABC-2 family transporter protein
MCKBDDEF_02666	2.37e-96	-	-	-	-	-	-	-	-
MCKBDDEF_02667	6.09e-161	-	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_02668	2.04e-203	-	-	-	T	-	-	-	Histidine kinase
MCKBDDEF_02669	3.15e-314	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MCKBDDEF_02670	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MCKBDDEF_02671	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MCKBDDEF_02672	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MCKBDDEF_02673	2.43e-265	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MCKBDDEF_02674	1.11e-283	ywfA	-	-	EGP	-	-	-	-transporter
MCKBDDEF_02675	3.85e-144	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MCKBDDEF_02676	1.19e-176	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MCKBDDEF_02677	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCKBDDEF_02678	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MCKBDDEF_02679	8.14e-265	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MCKBDDEF_02680	2.21e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MCKBDDEF_02681	2.94e-181	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
MCKBDDEF_02682	4.87e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MCKBDDEF_02683	2.03e-225	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MCKBDDEF_02684	9.79e-213	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MCKBDDEF_02685	4.54e-210	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_02686	8.76e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MCKBDDEF_02688	1.51e-234	-	-	-	-	-	-	-	-
MCKBDDEF_02691	1.32e-190	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MCKBDDEF_02692	1.65e-211	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_02693	3.78e-120	-	-	-	S	-	-	-	membrane
MCKBDDEF_02694	1.08e-67	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
MCKBDDEF_02695	2.48e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
MCKBDDEF_02696	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
MCKBDDEF_02697	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MCKBDDEF_02698	2.02e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
MCKBDDEF_02699	9.94e-316	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
MCKBDDEF_02700	4.16e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02701	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MCKBDDEF_02702	3.84e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
MCKBDDEF_02703	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
MCKBDDEF_02704	1.32e-14	-	-	-	-	-	-	-	-
MCKBDDEF_02705	1.23e-69	-	-	-	-	-	-	-	-
MCKBDDEF_02706	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MCKBDDEF_02707	1.58e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MCKBDDEF_02708	1.73e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MCKBDDEF_02710	1.38e-103	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MCKBDDEF_02711	3.01e-294	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
MCKBDDEF_02712	5.82e-307	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
MCKBDDEF_02714	2.21e-94	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_02715	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MCKBDDEF_02716	4.27e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MCKBDDEF_02717	5.43e-167	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
MCKBDDEF_02718	5.69e-22	ywiC	-	-	S	-	-	-	YwiC-like protein
MCKBDDEF_02719	2.91e-109	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
MCKBDDEF_02720	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MCKBDDEF_02721	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MCKBDDEF_02722	1.48e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
MCKBDDEF_02723	2.41e-158	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
MCKBDDEF_02724	3.02e-136	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MCKBDDEF_02725	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MCKBDDEF_02726	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MCKBDDEF_02727	1.13e-58	ywjC	-	-	-	-	-	-	-
MCKBDDEF_02728	8.09e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MCKBDDEF_02729	6.69e-283	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MCKBDDEF_02730	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MCKBDDEF_02731	8.4e-76	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MCKBDDEF_02732	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MCKBDDEF_02733	6.67e-120	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MCKBDDEF_02734	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
MCKBDDEF_02735	5.51e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MCKBDDEF_02736	2.22e-144	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MCKBDDEF_02737	5.55e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MCKBDDEF_02738	1.43e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MCKBDDEF_02739	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MCKBDDEF_02740	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MCKBDDEF_02741	5.56e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MCKBDDEF_02742	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MCKBDDEF_02743	2.02e-202	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MCKBDDEF_02744	8.54e-123	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MCKBDDEF_02745	6.14e-87	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCKBDDEF_02746	1.11e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MCKBDDEF_02747	1.4e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MCKBDDEF_02748	1.71e-78	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MCKBDDEF_02749	1.88e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MCKBDDEF_02750	2.02e-97	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
MCKBDDEF_02751	3.6e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MCKBDDEF_02752	1.36e-118	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MCKBDDEF_02753	1.2e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MCKBDDEF_02754	6.74e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MCKBDDEF_02755	3.68e-125	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MCKBDDEF_02756	1.99e-299	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MCKBDDEF_02757	6.42e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MCKBDDEF_02758	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
MCKBDDEF_02759	3e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MCKBDDEF_02760	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCKBDDEF_02761	1.66e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MCKBDDEF_02762	2.77e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCKBDDEF_02763	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MCKBDDEF_02764	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MCKBDDEF_02765	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MCKBDDEF_02766	8.24e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MCKBDDEF_02767	4.15e-117	ywmA	-	-	-	-	-	-	-
MCKBDDEF_02768	2.25e-45	ywzB	-	-	S	-	-	-	membrane
MCKBDDEF_02769	8.35e-175	ywmB	-	-	S	-	-	-	TATA-box binding
MCKBDDEF_02770	7.05e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MCKBDDEF_02771	4.93e-243	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MCKBDDEF_02772	2.59e-160	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MCKBDDEF_02773	1.5e-158	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MCKBDDEF_02775	1.06e-185	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MCKBDDEF_02776	3.1e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MCKBDDEF_02777	6.28e-116	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MCKBDDEF_02778	3.66e-108	ywmF	-	-	S	-	-	-	Peptidase M50
MCKBDDEF_02779	2.01e-16	csbD	-	-	K	-	-	-	CsbD-like
MCKBDDEF_02780	2.86e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
MCKBDDEF_02781	1.07e-81	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
MCKBDDEF_02782	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MCKBDDEF_02783	3.61e-87	ywnA	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02785	5.3e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
MCKBDDEF_02786	6.88e-80	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MCKBDDEF_02787	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MCKBDDEF_02788	6.01e-89	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
MCKBDDEF_02790	2.76e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
MCKBDDEF_02791	2.17e-187	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MCKBDDEF_02792	4.67e-95	ywnJ	-	-	S	-	-	-	VanZ like family
MCKBDDEF_02793	1.17e-131	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MCKBDDEF_02794	1.72e-266	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MCKBDDEF_02795	1.07e-75	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
MCKBDDEF_02796	1.32e-291	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MCKBDDEF_02797	1.13e-132	yjgF	-	-	Q	-	-	-	Isochorismatase family
MCKBDDEF_02798	2.31e-311	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
MCKBDDEF_02799	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
MCKBDDEF_02800	4.1e-272	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_02801	3.58e-93	ywoH	-	-	K	-	-	-	transcriptional
MCKBDDEF_02802	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MCKBDDEF_02803	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MCKBDDEF_02804	2e-171	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MCKBDDEF_02805	4.45e-186	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MCKBDDEF_02806	1.34e-257	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
MCKBDDEF_02807	3.15e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MCKBDDEF_02808	1.87e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MCKBDDEF_02809	1.52e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
MCKBDDEF_02810	4.49e-82	ywpG	-	-	-	-	-	-	-
MCKBDDEF_02811	1.47e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MCKBDDEF_02812	1.18e-181	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MCKBDDEF_02813	1.51e-201	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MCKBDDEF_02814	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MCKBDDEF_02815	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
MCKBDDEF_02816	1.74e-21	-	-	-	-	-	-	-	-
MCKBDDEF_02817	8.29e-151	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MCKBDDEF_02818	2.12e-155	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MCKBDDEF_02819	5.03e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MCKBDDEF_02820	8.72e-314	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MCKBDDEF_02821	1.2e-191	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MCKBDDEF_02824	2.97e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
MCKBDDEF_02825	0.0	ywqJ	-	-	S	-	-	-	Pre-toxin TG
MCKBDDEF_02826	5.28e-113	-	-	-	-	-	-	-	-
MCKBDDEF_02827	1.66e-65	-	-	-	-	-	-	-	-
MCKBDDEF_02829	7.58e-123	-	-	-	-	-	-	-	-
MCKBDDEF_02830	4.84e-170	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MCKBDDEF_02831	5.92e-203	-	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02832	2.58e-121	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
MCKBDDEF_02834	2.47e-113	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MCKBDDEF_02835	2e-130	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
MCKBDDEF_02836	3.53e-110	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MCKBDDEF_02837	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MCKBDDEF_02839	2.33e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MCKBDDEF_02840	6.3e-22	-	-	-	-	-	-	-	-
MCKBDDEF_02841	5.34e-269	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MCKBDDEF_02842	2.49e-183	cotB	-	-	-	ko:K06325	-	ko00000	-
MCKBDDEF_02843	3.43e-163	ywrJ	-	-	-	-	-	-	-
MCKBDDEF_02844	1.04e-306	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MCKBDDEF_02846	5.35e-215	alsR	-	-	K	-	-	-	LysR substrate binding domain
MCKBDDEF_02847	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MCKBDDEF_02848	5.71e-191	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MCKBDDEF_02849	1.75e-123	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
MCKBDDEF_02850	2.39e-115	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
MCKBDDEF_02851	1.15e-206	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MCKBDDEF_02852	4.4e-204	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MCKBDDEF_02853	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MCKBDDEF_02854	1.38e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MCKBDDEF_02855	2.94e-203	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MCKBDDEF_02856	3.66e-229	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MCKBDDEF_02857	5.06e-260	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
MCKBDDEF_02858	1.03e-245	-	-	-	E	-	-	-	Spore germination protein
MCKBDDEF_02859	1.26e-241	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MCKBDDEF_02861	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
MCKBDDEF_02862	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
MCKBDDEF_02863	1.39e-280	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MCKBDDEF_02864	4.04e-29	ywtC	-	-	-	-	-	-	-
MCKBDDEF_02865	6.43e-303	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MCKBDDEF_02866	6.84e-74	yttA	-	-	S	-	-	-	Pfam Transposase IS66
MCKBDDEF_02867	6.43e-203	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MCKBDDEF_02868	1.14e-229	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02869	1.99e-314	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MCKBDDEF_02870	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
MCKBDDEF_02871	8.96e-274	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MCKBDDEF_02872	1.66e-249	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MCKBDDEF_02873	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MCKBDDEF_02874	1.07e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MCKBDDEF_02875	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MCKBDDEF_02876	2.57e-272	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MCKBDDEF_02877	2.13e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MCKBDDEF_02878	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MCKBDDEF_02879	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MCKBDDEF_02880	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MCKBDDEF_02881	1.45e-194	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MCKBDDEF_02882	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MCKBDDEF_02883	2.64e-211	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MCKBDDEF_02884	2.86e-267	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MCKBDDEF_02885	4.48e-204	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MCKBDDEF_02886	1.86e-64	-	-	-	-	-	-	-	-
MCKBDDEF_02887	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
MCKBDDEF_02888	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MCKBDDEF_02889	4.92e-150	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MCKBDDEF_02890	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCKBDDEF_02891	4.87e-280	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
MCKBDDEF_02892	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MCKBDDEF_02893	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MCKBDDEF_02894	3.49e-148	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
MCKBDDEF_02895	4.68e-184	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MCKBDDEF_02896	4.67e-303	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MCKBDDEF_02897	3.12e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MCKBDDEF_02898	1.16e-235	yvhJ	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02899	2.94e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MCKBDDEF_02900	3.44e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MCKBDDEF_02901	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCKBDDEF_02902	1.03e-202	degV	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_02903	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MCKBDDEF_02904	3.56e-57	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
MCKBDDEF_02905	1.01e-99	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MCKBDDEF_02906	5.47e-98	yvyF	-	-	S	-	-	-	flagellar protein
MCKBDDEF_02907	6.14e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
MCKBDDEF_02908	3.64e-104	yvyG	-	-	NOU	-	-	-	FlgN protein
MCKBDDEF_02909	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MCKBDDEF_02910	1.4e-207	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MCKBDDEF_02911	2.8e-108	yviE	-	-	-	-	-	-	-
MCKBDDEF_02912	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MCKBDDEF_02913	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MCKBDDEF_02914	6.97e-153	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MCKBDDEF_02915	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MCKBDDEF_02916	5.79e-88	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MCKBDDEF_02917	4.35e-10	fliT	-	-	N	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MCKBDDEF_02918	1.35e-89	-	-	-	-	-	-	-	-
MCKBDDEF_02919	2.28e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MCKBDDEF_02920	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MCKBDDEF_02921	6.64e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MCKBDDEF_02922	6.85e-192	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MCKBDDEF_02923	5.11e-59	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MCKBDDEF_02924	8.68e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MCKBDDEF_02925	2.48e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MCKBDDEF_02926	7.31e-306	ywoF	-	-	P	-	-	-	Right handed beta helix region
MCKBDDEF_02927	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MCKBDDEF_02928	2.47e-73	swrA	-	-	S	-	-	-	Swarming motility protein
MCKBDDEF_02929	7.21e-281	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MCKBDDEF_02930	9.44e-240	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MCKBDDEF_02932	1.24e-33	-	-	-	Q	-	-	-	Thioesterase domain
MCKBDDEF_02933	2.93e-298	yvkA	-	-	P	-	-	-	-transporter
MCKBDDEF_02934	2.32e-144	yvkB	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02935	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
MCKBDDEF_02936	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_02937	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MCKBDDEF_02938	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MCKBDDEF_02939	3.29e-43	yvkN	-	-	-	-	-	-	-
MCKBDDEF_02940	4.87e-66	yvlA	-	-	-	-	-	-	-
MCKBDDEF_02941	5.54e-219	yvlB	-	-	S	-	-	-	Putative adhesin
MCKBDDEF_02942	4.01e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MCKBDDEF_02943	7.66e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MCKBDDEF_02944	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MCKBDDEF_02945	1.27e-135	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MCKBDDEF_02946	2.13e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MCKBDDEF_02947	6.1e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MCKBDDEF_02948	3.89e-285	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MCKBDDEF_02949	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MCKBDDEF_02950	5.27e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MCKBDDEF_02951	9.48e-157	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MCKBDDEF_02952	5.93e-111	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MCKBDDEF_02953	5.06e-178	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
MCKBDDEF_02954	1.22e-269	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MCKBDDEF_02955	2.14e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MCKBDDEF_02956	2.72e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MCKBDDEF_02957	1.17e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MCKBDDEF_02958	9.83e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MCKBDDEF_02959	2.67e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MCKBDDEF_02960	8e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MCKBDDEF_02961	9.88e-145	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MCKBDDEF_02962	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MCKBDDEF_02963	3.82e-156	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_02964	1.36e-245	sasA	-	-	T	-	-	-	Histidine kinase
MCKBDDEF_02965	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MCKBDDEF_02966	4.64e-202	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
MCKBDDEF_02967	3.13e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MCKBDDEF_02968	2.98e-112	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MCKBDDEF_02969	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MCKBDDEF_02970	1.28e-225	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MCKBDDEF_02971	7.32e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MCKBDDEF_02972	3.23e-49	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MCKBDDEF_02973	6.65e-182	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MCKBDDEF_02974	5.54e-105	-	-	-	M	-	-	-	Ribonuclease
MCKBDDEF_02975	1.69e-232	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCKBDDEF_02976	4.41e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MCKBDDEF_02977	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MCKBDDEF_02978	1.3e-69	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MCKBDDEF_02979	8.57e-134	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MCKBDDEF_02980	2.2e-205	yvdE	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_02981	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
MCKBDDEF_02982	1.49e-261	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MCKBDDEF_02983	1.1e-279	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MCKBDDEF_02984	5.29e-178	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MCKBDDEF_02985	3.08e-137	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MCKBDDEF_02986	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
MCKBDDEF_02987	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MCKBDDEF_02988	4.27e-120	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MCKBDDEF_02989	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MCKBDDEF_02990	3.17e-234	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MCKBDDEF_02991	4.05e-285	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
MCKBDDEF_02992	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MCKBDDEF_02994	1.31e-45	-	-	-	-	-	-	-	-
MCKBDDEF_02995	0.0	-	-	-	I	-	-	-	Pfam Lipase (class 3)
MCKBDDEF_02996	5e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MCKBDDEF_02997	2.29e-52	-	-	-	I	-	-	-	Pfam Lipase (class 3)
MCKBDDEF_02998	4.22e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MCKBDDEF_03000	1.01e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MCKBDDEF_03001	1.9e-119	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCKBDDEF_03002	4.16e-143	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
MCKBDDEF_03003	2.32e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
MCKBDDEF_03004	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MCKBDDEF_03005	1.99e-99	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
MCKBDDEF_03006	1.17e-155	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MCKBDDEF_03007	7.67e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MCKBDDEF_03008	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MCKBDDEF_03009	1.23e-277	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
MCKBDDEF_03010	2.74e-206	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
MCKBDDEF_03011	4.98e-272	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MCKBDDEF_03012	3.44e-262	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
MCKBDDEF_03013	6.27e-247	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MCKBDDEF_03014	2.6e-257	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
MCKBDDEF_03015	2.46e-248	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MCKBDDEF_03016	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCKBDDEF_03017	2.73e-140	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MCKBDDEF_03018	7.66e-77	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MCKBDDEF_03019	1.11e-281	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MCKBDDEF_03020	2.24e-237	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
MCKBDDEF_03021	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
MCKBDDEF_03022	2.67e-308	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MCKBDDEF_03023	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MCKBDDEF_03024	3.62e-155	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MCKBDDEF_03025	3.57e-281	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MCKBDDEF_03026	3.55e-172	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MCKBDDEF_03027	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MCKBDDEF_03028	1.44e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MCKBDDEF_03030	2.49e-07	-	-	-	S	ko:K07483	-	ko00000	leucine-zipper of insertion element IS481
MCKBDDEF_03031	1.37e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MCKBDDEF_03032	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MCKBDDEF_03033	1.9e-195	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
MCKBDDEF_03034	1.79e-214	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MCKBDDEF_03035	2.47e-146	-	-	-	S	ko:K07149	-	ko00000	Membrane
MCKBDDEF_03036	1.51e-232	yhjM	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_03037	4.71e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MCKBDDEF_03038	6.36e-204	yvbV	-	-	EG	-	-	-	EamA-like transporter family
MCKBDDEF_03039	1.24e-199	yvbU	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_03041	1.08e-242	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCKBDDEF_03042	4.51e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MCKBDDEF_03043	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MCKBDDEF_03045	3.44e-239	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MCKBDDEF_03046	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MCKBDDEF_03047	6.6e-276	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MCKBDDEF_03048	2.58e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MCKBDDEF_03049	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MCKBDDEF_03050	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MCKBDDEF_03051	1.63e-301	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
MCKBDDEF_03052	0.0	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MCKBDDEF_03053	1.83e-277	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MCKBDDEF_03054	3.35e-217	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
MCKBDDEF_03055	8.99e-293	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MCKBDDEF_03056	2.95e-187	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
MCKBDDEF_03057	2.89e-185	-	-	-	C	-	-	-	WbqC-like protein family
MCKBDDEF_03058	1.9e-163	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
MCKBDDEF_03059	4.84e-229	-	-	-	-	-	-	-	-
MCKBDDEF_03060	2.56e-268	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MCKBDDEF_03061	1.29e-105	yvbK	-	-	K	-	-	-	acetyltransferase
MCKBDDEF_03062	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MCKBDDEF_03063	7.3e-155	yvbI	-	-	M	-	-	-	Membrane
MCKBDDEF_03064	1.88e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
MCKBDDEF_03065	6.82e-128	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MCKBDDEF_03066	5.16e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MCKBDDEF_03067	4.63e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MCKBDDEF_03068	4.61e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MCKBDDEF_03069	6.21e-141	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MCKBDDEF_03070	3.42e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MCKBDDEF_03071	1.66e-267	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MCKBDDEF_03072	3.4e-146	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MCKBDDEF_03073	1.8e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MCKBDDEF_03074	2.09e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MCKBDDEF_03075	1.55e-161	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_03076	1.15e-155	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MCKBDDEF_03077	6.04e-173	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MCKBDDEF_03078	1.34e-158	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MCKBDDEF_03079	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MCKBDDEF_03080	2.44e-69	yvaP	-	-	K	-	-	-	transcriptional
MCKBDDEF_03081	3.52e-96	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MCKBDDEF_03082	9.53e-93	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
MCKBDDEF_03083	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
MCKBDDEF_03084	4.58e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MCKBDDEF_03085	1.7e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MCKBDDEF_03086	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MCKBDDEF_03087	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MCKBDDEF_03089	1.06e-39	-	-	-	S	-	-	-	Phage integrase family
MCKBDDEF_03092	1.88e-06	-	-	-	L	-	-	-	AAA ATPase domain
MCKBDDEF_03094	1.13e-179	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MCKBDDEF_03095	3.82e-204	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
MCKBDDEF_03096	3.69e-129	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MCKBDDEF_03097	5.65e-166	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MCKBDDEF_03098	2.91e-187	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MCKBDDEF_03099	7.29e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MCKBDDEF_03100	2.36e-155	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MCKBDDEF_03101	8.64e-179	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MCKBDDEF_03102	3.54e-232	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCKBDDEF_03103	3.52e-62	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
MCKBDDEF_03104	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MCKBDDEF_03105	1.03e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MCKBDDEF_03106	9.62e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MCKBDDEF_03107	2.81e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MCKBDDEF_03108	1.88e-39	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
MCKBDDEF_03109	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MCKBDDEF_03110	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MCKBDDEF_03111	1.84e-137	bdbD	-	-	O	-	-	-	Thioredoxin
MCKBDDEF_03112	3.05e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MCKBDDEF_03113	1.1e-189	-	-	-	S	-	-	-	Metallo-peptidase family M12
MCKBDDEF_03114	1.3e-138	yvgT	-	-	S	-	-	-	membrane
MCKBDDEF_03115	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MCKBDDEF_03116	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MCKBDDEF_03117	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MCKBDDEF_03118	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MCKBDDEF_03119	1.32e-111	yvgO	-	-	-	-	-	-	-
MCKBDDEF_03120	7.23e-200	yvgN	-	-	S	-	-	-	reductase
MCKBDDEF_03121	5.2e-255	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MCKBDDEF_03122	1.22e-249	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MCKBDDEF_03123	1.66e-218	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MCKBDDEF_03124	7.24e-245	-	-	-	T	-	-	-	Histidine kinase
MCKBDDEF_03125	4.32e-148	yfiK	-	-	K	-	-	-	Regulator
MCKBDDEF_03126	2.33e-126	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MCKBDDEF_03127	1.95e-178	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MCKBDDEF_03128	3.88e-211	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
MCKBDDEF_03129	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
MCKBDDEF_03130	4.11e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MCKBDDEF_03131	1.29e-20	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
MCKBDDEF_03132	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MCKBDDEF_03133	1.28e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MCKBDDEF_03134	3.29e-238	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCKBDDEF_03135	2.27e-224	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCKBDDEF_03136	1.39e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MCKBDDEF_03137	8.36e-89	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
MCKBDDEF_03138	8.91e-295	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MCKBDDEF_03139	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
MCKBDDEF_03140	3.23e-134	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MCKBDDEF_03141	1.67e-50	-	-	-	-	-	-	-	-
MCKBDDEF_03142	7.74e-172	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_03143	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
MCKBDDEF_03144	3.79e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MCKBDDEF_03145	8.63e-181	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MCKBDDEF_03146	1.93e-214	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MCKBDDEF_03147	7.3e-227	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCKBDDEF_03148	3.18e-281	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MCKBDDEF_03149	1.54e-131	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MCKBDDEF_03150	2.77e-289	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_03151	3.14e-66	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
MCKBDDEF_03152	9.74e-134	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MCKBDDEF_03153	1.43e-192	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MCKBDDEF_03154	2.99e-162	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MCKBDDEF_03155	3.48e-247	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_03156	8.35e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCKBDDEF_03157	2.93e-260	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MCKBDDEF_03158	2.16e-244	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MCKBDDEF_03159	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MCKBDDEF_03160	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
MCKBDDEF_03161	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MCKBDDEF_03162	1.8e-200	yuxN	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_03163	2.68e-32	-	-	-	-	-	-	-	-
MCKBDDEF_03164	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_03165	3.7e-163	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_03166	1.26e-303	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MCKBDDEF_03167	2.39e-102	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MCKBDDEF_03168	1.29e-195	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MCKBDDEF_03169	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MCKBDDEF_03170	7.61e-60	-	-	-	S	-	-	-	YusW-like protein
MCKBDDEF_03171	1.29e-192	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MCKBDDEF_03172	2.15e-52	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
MCKBDDEF_03173	2.83e-239	apbA	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MCKBDDEF_03174	4.14e-176	-	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
MCKBDDEF_03175	2.31e-201	-	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_03176	4.52e-202	yusT	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
MCKBDDEF_03177	1.81e-169	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MCKBDDEF_03178	1.24e-86	yusQ	-	-	S	-	-	-	Tautomerase enzyme
MCKBDDEF_03179	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
MCKBDDEF_03180	1.31e-89	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MCKBDDEF_03181	5.21e-71	yusN	-	-	M	-	-	-	Coat F domain
MCKBDDEF_03182	3.2e-58	-	-	-	-	-	-	-	-
MCKBDDEF_03183	8.5e-212	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MCKBDDEF_03184	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MCKBDDEF_03185	1.56e-277	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MCKBDDEF_03186	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MCKBDDEF_03187	7.13e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MCKBDDEF_03188	4.16e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MCKBDDEF_03189	1.8e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MCKBDDEF_03190	1.08e-82	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
MCKBDDEF_03191	1.64e-72	yusE	-	-	CO	-	-	-	Thioredoxin
MCKBDDEF_03192	1.29e-76	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
MCKBDDEF_03193	3.71e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MCKBDDEF_03194	1.91e-134	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MCKBDDEF_03195	9e-187	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MCKBDDEF_03196	5.13e-84	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MCKBDDEF_03197	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MCKBDDEF_03198	1.23e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MCKBDDEF_03199	2.31e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MCKBDDEF_03200	5.15e-100	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MCKBDDEF_03201	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MCKBDDEF_03202	2.94e-200	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MCKBDDEF_03203	6.17e-104	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
MCKBDDEF_03205	1.16e-48	-	-	-	-	-	-	-	-
MCKBDDEF_03206	2.72e-261	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MCKBDDEF_03207	5.74e-86	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
MCKBDDEF_03209	1.75e-28	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MCKBDDEF_03210	4.36e-94	-	-	-	-	-	-	-	-
MCKBDDEF_03212	2.73e-211	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MCKBDDEF_03213	1.57e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MCKBDDEF_03214	2.12e-312	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MCKBDDEF_03215	1.68e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MCKBDDEF_03216	8.84e-210	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MCKBDDEF_03217	2.16e-205	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MCKBDDEF_03218	4.84e-172	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MCKBDDEF_03219	4.53e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCKBDDEF_03220	4.09e-217	bsn	-	-	L	-	-	-	Ribonuclease
MCKBDDEF_03221	9.02e-295	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MCKBDDEF_03222	2.32e-299	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MCKBDDEF_03223	4.28e-274	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_03224	3.55e-30	-	-	-	-	-	-	-	-
MCKBDDEF_03225	2.77e-12	-	-	-	-	-	-	-	-
MCKBDDEF_03227	8.78e-18	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
MCKBDDEF_03228	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MCKBDDEF_03229	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MCKBDDEF_03230	3.04e-80	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
MCKBDDEF_03231	1.8e-217	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MCKBDDEF_03232	3.01e-186	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MCKBDDEF_03233	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MCKBDDEF_03234	2.75e-167	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MCKBDDEF_03235	8.24e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MCKBDDEF_03236	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MCKBDDEF_03237	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_03238	1.55e-95	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MCKBDDEF_03239	1.38e-178	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MCKBDDEF_03240	1.75e-108	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MCKBDDEF_03241	1.55e-250	yutH	-	-	S	-	-	-	Spore coat protein
MCKBDDEF_03242	8.26e-308	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MCKBDDEF_03243	5.41e-250	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MCKBDDEF_03244	6.76e-217	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MCKBDDEF_03245	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MCKBDDEF_03246	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MCKBDDEF_03247	1.34e-72	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_03248	4.03e-264	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MCKBDDEF_03249	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MCKBDDEF_03250	1.49e-273	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MCKBDDEF_03251	2.25e-207	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MCKBDDEF_03252	3.25e-81	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MCKBDDEF_03253	9.01e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MCKBDDEF_03254	4.15e-122	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MCKBDDEF_03256	5.3e-44	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
MCKBDDEF_03258	6.54e-157	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MCKBDDEF_03259	5.92e-93	-	-	-	CP	-	-	-	Membrane
MCKBDDEF_03260	2.32e-39	-	-	-	-	-	-	-	-
MCKBDDEF_03261	1.35e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MCKBDDEF_03263	4.19e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MCKBDDEF_03264	3.42e-300	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MCKBDDEF_03265	2.45e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
MCKBDDEF_03266	9.86e-153	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_03267	8.29e-100	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MCKBDDEF_03268	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MCKBDDEF_03269	8.19e-276	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MCKBDDEF_03270	3.73e-131	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MCKBDDEF_03271	1.13e-155	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
MCKBDDEF_03272	1.72e-209	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
MCKBDDEF_03273	2.03e-170	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MCKBDDEF_03274	3.2e-285	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MCKBDDEF_03275	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
MCKBDDEF_03276	7.94e-220	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
MCKBDDEF_03277	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCKBDDEF_03278	9.15e-45	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
MCKBDDEF_03279	3.06e-171	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
MCKBDDEF_03280	5.7e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MCKBDDEF_03281	1.22e-290	yukF	-	-	QT	-	-	-	Transcriptional regulator
MCKBDDEF_03282	1.94e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
MCKBDDEF_03283	5.28e-53	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MCKBDDEF_03284	6.52e-275	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MCKBDDEF_03285	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MCKBDDEF_03286	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MCKBDDEF_03287	8.01e-102	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
MCKBDDEF_03288	2.04e-169	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCKBDDEF_03289	1.57e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MCKBDDEF_03290	2.81e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MCKBDDEF_03291	2.67e-238	yueF	-	-	S	-	-	-	transporter activity
MCKBDDEF_03292	6.33e-46	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
MCKBDDEF_03293	5.46e-51	yueH	-	-	S	-	-	-	YueH-like protein
MCKBDDEF_03294	7.94e-90	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MCKBDDEF_03295	8.02e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
MCKBDDEF_03296	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MCKBDDEF_03297	5.64e-295	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
MCKBDDEF_03298	4.23e-67	yuzC	-	-	-	-	-	-	-
MCKBDDEF_03300	2.66e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
MCKBDDEF_03301	6.21e-190	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Polyprenyl synthetase
MCKBDDEF_03303	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_03304	1.23e-54	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_03305	8.07e-148	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MCKBDDEF_03306	4e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
MCKBDDEF_03307	1.21e-78	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MCKBDDEF_03308	5.47e-52	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MCKBDDEF_03309	1.23e-101	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MCKBDDEF_03310	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MCKBDDEF_03311	8.54e-67	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MCKBDDEF_03312	6.3e-90	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MCKBDDEF_03313	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MCKBDDEF_03315	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MCKBDDEF_03316	2.72e-238	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MCKBDDEF_03317	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_03318	4.98e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MCKBDDEF_03319	6.58e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MCKBDDEF_03320	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MCKBDDEF_03321	9.25e-101	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MCKBDDEF_03322	5.29e-95	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_03323	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MCKBDDEF_03324	3.4e-259	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MCKBDDEF_03325	3.22e-152	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
MCKBDDEF_03326	2.81e-88	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MCKBDDEF_03327	2.88e-289	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_03328	1.92e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MCKBDDEF_03329	4.25e-55	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
MCKBDDEF_03330	1.64e-199	yugF	-	-	I	-	-	-	Hydrolase
MCKBDDEF_03331	3.75e-109	alaR	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_03332	1.68e-266	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MCKBDDEF_03333	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MCKBDDEF_03334	3.14e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MCKBDDEF_03335	2.24e-284	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MCKBDDEF_03336	1.37e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
MCKBDDEF_03337	4.34e-152	ycaC	-	-	Q	-	-	-	Isochorismatase family
MCKBDDEF_03338	1.32e-131	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
MCKBDDEF_03339	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MCKBDDEF_03341	8.53e-95	yugN	-	-	S	-	-	-	YugN-like family
MCKBDDEF_03342	4.84e-231	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
MCKBDDEF_03343	4.93e-35	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
MCKBDDEF_03344	2.16e-23	-	-	-	-	-	-	-	-
MCKBDDEF_03345	1.67e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MCKBDDEF_03346	1.63e-296	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MCKBDDEF_03347	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MCKBDDEF_03348	7.72e-98	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MCKBDDEF_03349	2.01e-242	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MCKBDDEF_03350	6.59e-55	-	-	-	-	-	-	-	-
MCKBDDEF_03351	2.22e-179	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MCKBDDEF_03352	1.32e-315	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MCKBDDEF_03353	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MCKBDDEF_03354	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MCKBDDEF_03355	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MCKBDDEF_03356	6.95e-127	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MCKBDDEF_03357	1.29e-235	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MCKBDDEF_03358	9.96e-251	yubA	-	-	S	-	-	-	transporter activity
MCKBDDEF_03359	6.56e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MCKBDDEF_03361	4.37e-68	yjcN	-	-	-	-	-	-	-
MCKBDDEF_03362	3.73e-157	-	-	-	G	-	-	-	Cupin
MCKBDDEF_03363	1.07e-280	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MCKBDDEF_03364	2.58e-191	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MCKBDDEF_03365	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MCKBDDEF_03366	9.28e-121	yuaB	-	-	-	-	-	-	-
MCKBDDEF_03367	7.09e-125	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MCKBDDEF_03368	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MCKBDDEF_03369	1.74e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MCKBDDEF_03370	6.79e-141	-	-	-	S	-	-	-	MOSC domain
MCKBDDEF_03371	2.98e-104	yuaE	-	-	S	-	-	-	DinB superfamily
MCKBDDEF_03372	5.61e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MCKBDDEF_03373	1.08e-277	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MCKBDDEF_03374	6.67e-123	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MCKBDDEF_03376	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MCKBDDEF_03398	1.82e-102	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MCKBDDEF_03399	3.03e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MCKBDDEF_03400	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MCKBDDEF_03401	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MCKBDDEF_03402	2.52e-199	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MCKBDDEF_03403	7.52e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MCKBDDEF_03404	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MCKBDDEF_03405	2.88e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MCKBDDEF_03406	1.92e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
MCKBDDEF_03407	1.06e-234	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MCKBDDEF_03408	4.48e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MCKBDDEF_03409	1.23e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MCKBDDEF_03410	9.31e-137	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MCKBDDEF_03411	8.41e-54	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MCKBDDEF_03412	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MCKBDDEF_03413	1.26e-100	ytkA	-	-	S	-	-	-	YtkA-like
MCKBDDEF_03415	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MCKBDDEF_03416	1.23e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
MCKBDDEF_03417	1.01e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MCKBDDEF_03418	5.66e-169	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MCKBDDEF_03419	3.39e-181	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MCKBDDEF_03420	1.07e-237	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MCKBDDEF_03421	1.84e-188	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MCKBDDEF_03422	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
MCKBDDEF_03423	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MCKBDDEF_03424	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MCKBDDEF_03425	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MCKBDDEF_03426	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MCKBDDEF_03427	4.06e-84	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MCKBDDEF_03428	6.95e-194	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MCKBDDEF_03429	2.02e-271	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MCKBDDEF_03430	1.49e-184	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
MCKBDDEF_03432	1.26e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MCKBDDEF_03433	5.76e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
MCKBDDEF_03434	1.43e-52	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
MCKBDDEF_03436	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MCKBDDEF_03437	4.38e-209	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_03438	4.31e-213	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MCKBDDEF_03439	2.68e-228	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MCKBDDEF_03440	2.02e-206	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MCKBDDEF_03441	2.12e-161	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_03442	4.75e-288	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MCKBDDEF_03443	9.07e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_03444	6.12e-222	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
MCKBDDEF_03445	4.63e-174	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MCKBDDEF_03446	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MCKBDDEF_03447	1.55e-162	ywaF	-	-	S	-	-	-	Integral membrane protein
MCKBDDEF_03448	3.35e-269	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MCKBDDEF_03449	4.59e-175	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MCKBDDEF_03450	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
MCKBDDEF_03451	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MCKBDDEF_03452	3.51e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
MCKBDDEF_03453	6.9e-111	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
MCKBDDEF_03454	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MCKBDDEF_03455	2.88e-184	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MCKBDDEF_03456	2.44e-212	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MCKBDDEF_03457	3.24e-310	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MCKBDDEF_03458	7.81e-239	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_03459	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
MCKBDDEF_03460	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MCKBDDEF_03461	3.73e-299	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MCKBDDEF_03462	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCKBDDEF_03463	5.02e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MCKBDDEF_03464	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MCKBDDEF_03465	2.58e-163	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MCKBDDEF_03466	1.75e-276	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
MCKBDDEF_03467	1.48e-290	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MCKBDDEF_03468	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
MCKBDDEF_03469	6.81e-222	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MCKBDDEF_03470	6.34e-132	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MCKBDDEF_03471	1.47e-216	ytlQ	-	-	-	-	-	-	-
MCKBDDEF_03472	1.61e-224	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MCKBDDEF_03473	2.93e-199	ytmP	-	-	M	-	-	-	Phosphotransferase
MCKBDDEF_03474	5.51e-60	ytzH	-	-	S	-	-	-	YtzH-like protein
MCKBDDEF_03475	1.07e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MCKBDDEF_03476	4.38e-208	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MCKBDDEF_03477	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MCKBDDEF_03478	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
MCKBDDEF_03479	5.06e-259	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MCKBDDEF_03480	1.94e-100	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MCKBDDEF_03481	5.47e-76	ytpP	-	-	CO	-	-	-	Thioredoxin
MCKBDDEF_03482	2.4e-190	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MCKBDDEF_03483	2.08e-139	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MCKBDDEF_03484	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MCKBDDEF_03485	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MCKBDDEF_03486	5.38e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MCKBDDEF_03487	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MCKBDDEF_03488	1.19e-57	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MCKBDDEF_03489	1.54e-249	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MCKBDDEF_03490	1.39e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MCKBDDEF_03491	5.2e-186	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MCKBDDEF_03492	4.99e-154	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MCKBDDEF_03493	1.94e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MCKBDDEF_03494	2.06e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
MCKBDDEF_03495	2.84e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MCKBDDEF_03496	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MCKBDDEF_03497	5.98e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MCKBDDEF_03498	8.79e-64	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
MCKBDDEF_03499	2.86e-160	ygaZ	-	-	E	-	-	-	AzlC protein
MCKBDDEF_03500	9.06e-190	-	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_03501	1.43e-192	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MCKBDDEF_03502	2.39e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MCKBDDEF_03504	1.65e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MCKBDDEF_03506	1.58e-284	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MCKBDDEF_03507	2.3e-23	-	-	-	-	-	-	-	-
MCKBDDEF_03509	7.11e-19	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MCKBDDEF_03510	9e-60	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
MCKBDDEF_03512	3.13e-133	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MCKBDDEF_03513	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MCKBDDEF_03514	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MCKBDDEF_03515	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
MCKBDDEF_03516	5.2e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MCKBDDEF_03517	2.82e-140	yttP	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_03518	1.99e-194	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MCKBDDEF_03519	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MCKBDDEF_03520	9.7e-309	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MCKBDDEF_03521	1.12e-265	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MCKBDDEF_03522	2.09e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MCKBDDEF_03523	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MCKBDDEF_03524	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MCKBDDEF_03525	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
MCKBDDEF_03526	2.32e-196	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MCKBDDEF_03527	6.39e-235	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MCKBDDEF_03528	2.77e-114	yteJ	-	-	S	-	-	-	RDD family
MCKBDDEF_03529	1.22e-154	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MCKBDDEF_03530	4.77e-100	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MCKBDDEF_03531	1.36e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MCKBDDEF_03532	8.37e-232	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MCKBDDEF_03533	2.33e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MCKBDDEF_03534	1.64e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MCKBDDEF_03535	2.49e-296	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MCKBDDEF_03536	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MCKBDDEF_03538	8.38e-184	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MCKBDDEF_03539	4.16e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MCKBDDEF_03540	7.89e-304	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MCKBDDEF_03541	3.57e-62	ytpI	-	-	S	-	-	-	YtpI-like protein
MCKBDDEF_03542	2.14e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MCKBDDEF_03543	7.04e-32	-	-	-	-	-	-	-	-
MCKBDDEF_03544	2.64e-114	ytrI	-	-	-	-	-	-	-
MCKBDDEF_03545	4.94e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MCKBDDEF_03546	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MCKBDDEF_03547	4.23e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MCKBDDEF_03548	8.46e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MCKBDDEF_03549	1.15e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MCKBDDEF_03550	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MCKBDDEF_03551	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MCKBDDEF_03552	3.42e-84	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MCKBDDEF_03553	4.05e-247	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MCKBDDEF_03554	5.65e-96	ytwI	-	-	S	-	-	-	membrane
MCKBDDEF_03555	9.5e-84	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MCKBDDEF_03556	1.35e-69	-	-	-	-	-	-	-	-
MCKBDDEF_03557	1.42e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MCKBDDEF_03558	1.08e-307	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MCKBDDEF_03559	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MCKBDDEF_03560	2.38e-164	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MCKBDDEF_03561	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MCKBDDEF_03562	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MCKBDDEF_03563	1.64e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MCKBDDEF_03564	2.84e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MCKBDDEF_03565	5.08e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MCKBDDEF_03566	4.54e-205	ytbE	-	-	S	-	-	-	reductase
MCKBDDEF_03567	8e-259	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
MCKBDDEF_03568	1.69e-89	ytcD	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_03569	1.48e-247	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MCKBDDEF_03570	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MCKBDDEF_03571	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MCKBDDEF_03572	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MCKBDDEF_03573	2.02e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MCKBDDEF_03574	1.05e-138	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MCKBDDEF_03575	1.99e-197	ytxC	-	-	S	-	-	-	YtxC-like family
MCKBDDEF_03576	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MCKBDDEF_03577	1.2e-192	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MCKBDDEF_03578	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCKBDDEF_03579	1.05e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MCKBDDEF_03580	1.59e-68	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
MCKBDDEF_03581	3.1e-147	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MCKBDDEF_03582	1.79e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MCKBDDEF_03583	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MCKBDDEF_03584	2.3e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MCKBDDEF_03585	1.34e-56	ysdA	-	-	S	-	-	-	Membrane
MCKBDDEF_03586	6.58e-88	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MCKBDDEF_03587	1.85e-263	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MCKBDDEF_03588	1.11e-237	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MCKBDDEF_03589	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MCKBDDEF_03590	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MCKBDDEF_03591	3.43e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MCKBDDEF_03592	6.57e-180	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MCKBDDEF_03593	1.58e-283	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MCKBDDEF_03594	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MCKBDDEF_03595	4.38e-215	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MCKBDDEF_03596	1.18e-191	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
MCKBDDEF_03597	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MCKBDDEF_03598	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MCKBDDEF_03599	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MCKBDDEF_03600	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
MCKBDDEF_03601	5.07e-261	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MCKBDDEF_03602	1.07e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MCKBDDEF_03603	2.2e-171	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCKBDDEF_03604	2.19e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MCKBDDEF_03605	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MCKBDDEF_03606	3.08e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCKBDDEF_03607	1.47e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MCKBDDEF_03608	6.04e-109	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MCKBDDEF_03609	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MCKBDDEF_03610	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MCKBDDEF_03611	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MCKBDDEF_03612	1.12e-93	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
MCKBDDEF_03613	2.11e-50	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
MCKBDDEF_03614	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MCKBDDEF_03615	6.22e-134	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_03616	1.43e-177	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MCKBDDEF_03617	1.23e-177	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MCKBDDEF_03618	2.48e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MCKBDDEF_03619	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MCKBDDEF_03620	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MCKBDDEF_03621	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MCKBDDEF_03622	1.74e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MCKBDDEF_03623	2.45e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MCKBDDEF_03624	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MCKBDDEF_03625	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MCKBDDEF_03626	4.34e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MCKBDDEF_03627	8.94e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MCKBDDEF_03628	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_03629	3.77e-97	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MCKBDDEF_03630	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MCKBDDEF_03631	5.21e-254	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MCKBDDEF_03632	1.18e-169	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MCKBDDEF_03633	1.59e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MCKBDDEF_03634	9.55e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MCKBDDEF_03639	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MCKBDDEF_03640	2.06e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MCKBDDEF_03641	2.75e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MCKBDDEF_03642	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MCKBDDEF_03643	4.12e-253	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MCKBDDEF_03644	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MCKBDDEF_03645	1.53e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MCKBDDEF_03646	3.33e-241	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
MCKBDDEF_03647	2.18e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MCKBDDEF_03648	3.28e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MCKBDDEF_03649	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MCKBDDEF_03650	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MCKBDDEF_03651	1.79e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MCKBDDEF_03652	1.6e-113	ysxD	-	-	-	-	-	-	-
MCKBDDEF_03653	4.36e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MCKBDDEF_03654	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MCKBDDEF_03655	5.19e-223	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MCKBDDEF_03656	1.56e-181	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MCKBDDEF_03657	3.43e-236	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MCKBDDEF_03658	2.68e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MCKBDDEF_03659	3.06e-300	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MCKBDDEF_03660	1.89e-251	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MCKBDDEF_03661	4.38e-35	-	-	-	-	-	-	-	-
MCKBDDEF_03662	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MCKBDDEF_03663	2.28e-308	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MCKBDDEF_03664	1.27e-171	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MCKBDDEF_03665	8.52e-207	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
MCKBDDEF_03666	2.36e-130	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MCKBDDEF_03667	2.5e-164	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MCKBDDEF_03668	1.06e-234	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MCKBDDEF_03669	4.34e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MCKBDDEF_03670	6.14e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MCKBDDEF_03671	4.62e-153	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MCKBDDEF_03672	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MCKBDDEF_03673	1.39e-188	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MCKBDDEF_03674	4.19e-205	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MCKBDDEF_03675	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MCKBDDEF_03676	1.42e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MCKBDDEF_03677	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MCKBDDEF_03678	2.87e-137	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MCKBDDEF_03679	2.89e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MCKBDDEF_03680	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MCKBDDEF_03681	8.16e-206	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MCKBDDEF_03682	1.96e-120	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MCKBDDEF_03683	7.79e-283	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MCKBDDEF_03684	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MCKBDDEF_03685	1.23e-194	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MCKBDDEF_03686	4.96e-271	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MCKBDDEF_03687	6.31e-250	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MCKBDDEF_03688	8.92e-61	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MCKBDDEF_03690	1.21e-120	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MCKBDDEF_03691	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MCKBDDEF_03692	3.57e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MCKBDDEF_03693	9.76e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MCKBDDEF_03694	5.79e-246	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MCKBDDEF_03695	8.2e-293	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MCKBDDEF_03696	2.09e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MCKBDDEF_03697	9.08e-81	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MCKBDDEF_03698	4.79e-142	yrbG	-	-	S	-	-	-	membrane
MCKBDDEF_03699	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MCKBDDEF_03700	3.45e-68	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MCKBDDEF_03701	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MCKBDDEF_03702	1.26e-111	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MCKBDDEF_03703	2.23e-62	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MCKBDDEF_03704	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MCKBDDEF_03705	5.1e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MCKBDDEF_03706	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MCKBDDEF_03707	2.86e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MCKBDDEF_03708	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MCKBDDEF_03711	4.97e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MCKBDDEF_03712	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MCKBDDEF_03713	9.74e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MCKBDDEF_03714	7.55e-303	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MCKBDDEF_03715	9.19e-84	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MCKBDDEF_03716	4.24e-269	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MCKBDDEF_03717	3.55e-282	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MCKBDDEF_03718	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MCKBDDEF_03719	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MCKBDDEF_03720	3.14e-103	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MCKBDDEF_03721	8.4e-42	yrzR	-	-	-	-	-	-	-
MCKBDDEF_03722	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
MCKBDDEF_03723	1.54e-138	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MCKBDDEF_03724	1.13e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MCKBDDEF_03725	3.14e-189	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MCKBDDEF_03726	4.45e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MCKBDDEF_03727	1.15e-237	yrrI	-	-	S	-	-	-	AI-2E family transporter
MCKBDDEF_03728	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MCKBDDEF_03729	1.1e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MCKBDDEF_03730	2.72e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MCKBDDEF_03731	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MCKBDDEF_03732	4.67e-258	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MCKBDDEF_03733	2.32e-153	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MCKBDDEF_03734	3.64e-221	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
MCKBDDEF_03735	1.09e-311	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
MCKBDDEF_03736	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MCKBDDEF_03737	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MCKBDDEF_03738	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
MCKBDDEF_03739	2.92e-123	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MCKBDDEF_03740	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
MCKBDDEF_03741	2.83e-152	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
MCKBDDEF_03742	8.02e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MCKBDDEF_03743	1.61e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MCKBDDEF_03744	2.56e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MCKBDDEF_03745	1.92e-46	yrhC	-	-	S	-	-	-	YrhC-like protein
MCKBDDEF_03746	6.49e-104	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MCKBDDEF_03747	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
MCKBDDEF_03748	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MCKBDDEF_03749	3.96e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
MCKBDDEF_03750	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
MCKBDDEF_03751	9.01e-121	yrhH	-	-	Q	-	-	-	methyltransferase
MCKBDDEF_03752	4.77e-130	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
MCKBDDEF_03753	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MCKBDDEF_03754	9.68e-273	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_03755	2.17e-210	yybE	-	-	K	-	-	-	Transcriptional regulator
MCKBDDEF_03756	1.13e-107	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MCKBDDEF_03757	2.81e-232	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
MCKBDDEF_03758	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
MCKBDDEF_03759	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MCKBDDEF_03760	3.44e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MCKBDDEF_03761	2.9e-168	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MCKBDDEF_03762	2.91e-187	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MCKBDDEF_03763	2.06e-190	supH	-	-	S	-	-	-	hydrolase
MCKBDDEF_03764	4.76e-121	-	-	-	S	-	-	-	DinB family
MCKBDDEF_03765	8.64e-105	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
MCKBDDEF_03766	1.95e-282	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
MCKBDDEF_03767	4.56e-34	-	-	-	K	-	-	-	acetyltransferase
MCKBDDEF_03768	5.27e-126	yqaC	-	-	F	-	-	-	adenylate kinase activity
MCKBDDEF_03769	2.4e-132	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MCKBDDEF_03771	8.05e-278	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MCKBDDEF_03773	7.69e-159	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
MCKBDDEF_03774	1.27e-306	yrkQ	-	-	T	-	-	-	Histidine kinase
MCKBDDEF_03775	1.84e-91	psiE	-	-	S	ko:K13256	-	ko00000	Belongs to the PsiE family
MCKBDDEF_03776	2.6e-118	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MCKBDDEF_03777	1.03e-201	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
MCKBDDEF_03779	2.52e-68	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCKBDDEF_03780	1.03e-60	-	-	-	D	-	-	-	nuclear chromosome segregation
MCKBDDEF_03781	1.63e-77	yqaQ	-	-	L	-	-	-	Transposase
MCKBDDEF_03782	3.43e-77	yjcP	-	-	-	-	-	-	-
MCKBDDEF_03783	3.83e-61	-	-	-	S	-	-	-	YjcQ protein
MCKBDDEF_03784	4.67e-16	-	-	-	-	-	-	-	-
MCKBDDEF_03785	7.78e-91	-	-	-	K	-	-	-	MerR family transcriptional regulator
MCKBDDEF_03786	1.04e-174	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Aldo/keto reductase family
MCKBDDEF_03788	1.6e-26	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MCKBDDEF_03789	1.62e-140	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MCKBDDEF_03790	5.83e-35	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MCKBDDEF_03791	2.85e-46	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCKBDDEF_03792	1.36e-80	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MCKBDDEF_03793	3.28e-279	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MCKBDDEF_03794	5.88e-32	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MCKBDDEF_03795	4.93e-138	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
MCKBDDEF_03796	8.09e-181	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MCKBDDEF_03797	3.99e-176	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MCKBDDEF_03799	5.51e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MCKBDDEF_03800	3.23e-271	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MCKBDDEF_03801	1.2e-200	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MCKBDDEF_03802	1.81e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MCKBDDEF_03803	2.89e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MCKBDDEF_03804	6.89e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MCKBDDEF_03805	4.65e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MCKBDDEF_03806	5.67e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
MCKBDDEF_03807	1.19e-192	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MCKBDDEF_03808	2.81e-134	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MCKBDDEF_03809	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MCKBDDEF_03810	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MCKBDDEF_03811	3.84e-234	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MCKBDDEF_03812	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MCKBDDEF_03813	2.51e-260	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MCKBDDEF_03814	2.14e-278	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MCKBDDEF_03815	2.1e-71	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
MCKBDDEF_03816	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MCKBDDEF_03817	3.95e-274	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MCKBDDEF_03818	2.73e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MCKBDDEF_03819	5.18e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MCKBDDEF_03820	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MCKBDDEF_03821	4.93e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MCKBDDEF_03822	1.09e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MCKBDDEF_03823	1.01e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MCKBDDEF_03824	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MCKBDDEF_03825	1.37e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MCKBDDEF_03826	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MCKBDDEF_03827	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MCKBDDEF_03828	1.28e-293	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MCKBDDEF_03829	4.78e-177	yqfA	-	-	S	-	-	-	UPF0365 protein
MCKBDDEF_03830	1.52e-77	yqfB	-	-	-	-	-	-	-
MCKBDDEF_03831	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MCKBDDEF_03832	3.72e-282	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MCKBDDEF_03833	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MCKBDDEF_03834	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MCKBDDEF_03835	4.13e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MCKBDDEF_03836	6.41e-84	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MCKBDDEF_03837	1.92e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MCKBDDEF_03838	1.42e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MCKBDDEF_03839	6e-24	-	-	-	S	-	-	-	YqzL-like protein
MCKBDDEF_03840	8.73e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MCKBDDEF_03841	5.19e-223	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MCKBDDEF_03842	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MCKBDDEF_03843	5.89e-145	ccpN	-	-	K	-	-	-	CBS domain
MCKBDDEF_03844	5.46e-192	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MCKBDDEF_03845	5.52e-112	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MCKBDDEF_03846	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MCKBDDEF_03847	3.97e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MCKBDDEF_03848	9.68e-83	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants