ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HLADNGJO_00001 4.74e-23 - - - - - - - -
HLADNGJO_00002 1.19e-41 - - - S - - - Transglycosylase associated protein
HLADNGJO_00003 3.37e-96 asp1 - - S - - - Asp23 family, cell envelope-related function
HLADNGJO_00004 3.87e-114 - - - - - - - -
HLADNGJO_00005 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HLADNGJO_00006 5.47e-197 is18 - - L - - - COG2801 Transposase and inactivated derivatives
HLADNGJO_00007 1.21e-264 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLADNGJO_00008 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLADNGJO_00009 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HLADNGJO_00010 3.59e-240 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HLADNGJO_00011 1.85e-200 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HLADNGJO_00012 8.91e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLADNGJO_00013 2.19e-87 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HLADNGJO_00014 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLADNGJO_00015 3.02e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HLADNGJO_00016 1.52e-93 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HLADNGJO_00017 3.81e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HLADNGJO_00018 1.57e-165 - - - F - - - glutamine amidotransferase
HLADNGJO_00019 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HLADNGJO_00020 1.39e-314 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HLADNGJO_00021 8.57e-248 - 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HLADNGJO_00022 3.81e-227 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
HLADNGJO_00023 3.92e-217 - - - G - - - Phosphotransferase enzyme family
HLADNGJO_00024 1.95e-221 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HLADNGJO_00025 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HLADNGJO_00026 2.74e-203 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HLADNGJO_00027 2.87e-271 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HLADNGJO_00029 6.83e-135 - - - IQ - - - KR domain
HLADNGJO_00030 8.28e-292 - - - L - - - MULE transposase domain
HLADNGJO_00031 1.03e-16 - - - IQ - - - KR domain
HLADNGJO_00032 5.25e-197 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HLADNGJO_00033 1.19e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_00034 1.68e-149 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
HLADNGJO_00035 3.39e-147 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
HLADNGJO_00037 3.05e-108 - - - S - - - MmgE/PrpD family
HLADNGJO_00038 3.62e-215 - 4.3.2.2, 5.5.1.2 - F ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminus
HLADNGJO_00039 1.71e-184 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 Peptidase dimerisation domain
HLADNGJO_00040 5.02e-99 yxeO - - E ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HLADNGJO_00041 1.2e-98 yxeN - - U ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
HLADNGJO_00042 5.11e-60 yxeL - - K - - - acetyltransferase
HLADNGJO_00043 3.6e-77 yxeM - - ET ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HLADNGJO_00045 1.87e-270 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HLADNGJO_00046 1.98e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HLADNGJO_00047 5.22e-111 - - - K - - - Transcriptional regulator
HLADNGJO_00048 1.27e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLADNGJO_00049 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLADNGJO_00050 5.1e-74 - - - - - - - -
HLADNGJO_00051 1.05e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLADNGJO_00052 9.06e-232 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HLADNGJO_00053 4.82e-72 - - - - - - - -
HLADNGJO_00055 5.81e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HLADNGJO_00056 1.34e-51 - - - S - - - integral membrane protein
HLADNGJO_00057 1.08e-53 - - - S - - - integral membrane protein
HLADNGJO_00058 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLADNGJO_00059 3.4e-178 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLADNGJO_00060 7.71e-185 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HLADNGJO_00061 2.14e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLADNGJO_00062 5.6e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HLADNGJO_00063 2.09e-90 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HLADNGJO_00064 1.66e-51 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HLADNGJO_00065 5.02e-270 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HLADNGJO_00066 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
HLADNGJO_00067 8.45e-97 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HLADNGJO_00068 6.66e-135 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HLADNGJO_00069 2.01e-05 - - - K - - - LysR substrate binding domain
HLADNGJO_00070 2.62e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLADNGJO_00071 1.03e-202 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HLADNGJO_00072 5.05e-136 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLADNGJO_00073 1.55e-151 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HLADNGJO_00074 3.82e-133 cadD - - P - - - Cadmium resistance transporter
HLADNGJO_00075 1.41e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_00076 5.98e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_00078 9.49e-283 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HLADNGJO_00080 2.06e-66 - - - T - - - Transcriptional regulatory protein, C terminal
HLADNGJO_00081 1.04e-77 - - - T - - - His Kinase A (phosphoacceptor) domain
HLADNGJO_00082 1.73e-71 - - - C - - - FMN binding
HLADNGJO_00083 5.67e-258 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLADNGJO_00084 1.84e-138 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HLADNGJO_00085 4.58e-289 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HLADNGJO_00086 1.14e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HLADNGJO_00087 9.59e-104 - - - K - - - 2 iron, 2 sulfur cluster binding
HLADNGJO_00088 0.0 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HLADNGJO_00089 8.79e-284 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLADNGJO_00090 4.15e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HLADNGJO_00091 4.92e-141 - - - C - - - aldo keto reductase
HLADNGJO_00092 3.72e-145 pgm1 - - G - - - phosphoglycerate mutase
HLADNGJO_00094 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLADNGJO_00095 1.56e-255 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HLADNGJO_00096 1.52e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
HLADNGJO_00097 4.55e-74 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HLADNGJO_00098 5.43e-183 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLADNGJO_00099 3.25e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HLADNGJO_00100 1.21e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLADNGJO_00101 5.12e-132 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HLADNGJO_00102 2.12e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HLADNGJO_00103 3.18e-140 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HLADNGJO_00104 8.77e-73 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HLADNGJO_00105 4.67e-186 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HLADNGJO_00106 2.55e-215 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
HLADNGJO_00107 3.33e-63 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLADNGJO_00108 5.21e-11 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLADNGJO_00109 1.12e-123 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLADNGJO_00110 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_00111 1.96e-258 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLADNGJO_00112 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HLADNGJO_00113 1.39e-86 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLADNGJO_00114 1.21e-244 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLADNGJO_00115 3.87e-80 - - - - - - - -
HLADNGJO_00116 2.36e-213 - - - L ko:K07497 - ko00000 Integrase core domain
HLADNGJO_00117 1.68e-61 - - - L ko:K07483 - ko00000 Transposase
HLADNGJO_00118 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HLADNGJO_00119 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HLADNGJO_00120 6.65e-121 ybcH - - D ko:K06889 - ko00000 Alpha beta
HLADNGJO_00121 1.02e-69 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HLADNGJO_00122 7.82e-240 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLADNGJO_00123 3.05e-220 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLADNGJO_00124 2.17e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HLADNGJO_00126 1.37e-196 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
HLADNGJO_00127 2.2e-227 - - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HLADNGJO_00128 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HLADNGJO_00129 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HLADNGJO_00130 3.04e-23 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_00131 2.12e-74 - - - L - - - Helix-turn-helix domain
HLADNGJO_00132 8.1e-316 - - - U - - - Belongs to the major facilitator superfamily
HLADNGJO_00133 2.15e-235 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HLADNGJO_00134 3.22e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLADNGJO_00135 1.49e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLADNGJO_00136 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLADNGJO_00137 5.5e-67 ylxQ - - J - - - ribosomal protein
HLADNGJO_00138 5.27e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HLADNGJO_00139 6.7e-283 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HLADNGJO_00140 8.99e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HLADNGJO_00141 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HLADNGJO_00142 4.36e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HLADNGJO_00143 1.43e-250 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HLADNGJO_00144 1.17e-262 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HLADNGJO_00145 1.19e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HLADNGJO_00146 1.09e-273 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
HLADNGJO_00147 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLADNGJO_00148 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLADNGJO_00149 8.02e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HLADNGJO_00150 1.17e-173 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HLADNGJO_00151 7.73e-185 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLADNGJO_00152 6.51e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLADNGJO_00153 4.64e-54 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HLADNGJO_00154 2.04e-87 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HLADNGJO_00155 4.14e-198 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLADNGJO_00156 3.14e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HLADNGJO_00157 7.65e-62 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HLADNGJO_00158 6.86e-176 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HLADNGJO_00159 3.06e-150 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HLADNGJO_00160 1.05e-36 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HLADNGJO_00161 1.97e-49 ynzC - - S - - - UPF0291 protein
HLADNGJO_00162 4.36e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLADNGJO_00163 9.01e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HLADNGJO_00164 2.76e-155 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
HLADNGJO_00165 1.52e-307 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
HLADNGJO_00166 1.12e-109 lutC - - S ko:K00782 - ko00000 LUD domain
HLADNGJO_00167 7.2e-38 - - - M - - - LPXTG-motif cell wall anchor domain protein
HLADNGJO_00168 1.54e-67 - - - M - - - LPXTG-motif cell wall anchor domain protein
HLADNGJO_00169 1.99e-11 - - - Q - - - Signal peptide protein, YSIRK family
HLADNGJO_00170 3.02e-35 yitW - - S - - - DNA methyltransferase
HLADNGJO_00171 3.09e-141 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HLADNGJO_00172 4.67e-82 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HLADNGJO_00174 2.94e-255 - - - L - - - MULE transposase domain
HLADNGJO_00176 5.81e-193 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_00177 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HLADNGJO_00178 4.76e-275 - - - G - - - Major Facilitator Superfamily
HLADNGJO_00179 2.46e-215 - - - L ko:K07497 - ko00000 Integrase core domain
HLADNGJO_00180 1.01e-61 - - - L ko:K07483 - ko00000 Transposase
HLADNGJO_00181 4.47e-20 - - - G - - - Major Facilitator Superfamily
HLADNGJO_00182 7.88e-215 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLADNGJO_00183 2.01e-20 - 2.1.1.144, 2.1.1.197 - FG ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 trans-aconitate 2-methyltransferase activity
HLADNGJO_00184 9.25e-55 tnp1216 - - L ko:K07498 - ko00000 DDE domain
HLADNGJO_00185 1.78e-297 yagE - - E - - - Amino acid permease
HLADNGJO_00186 1.4e-279 - - - S - - - Domain of unknown function (DUF389)
HLADNGJO_00187 1.58e-70 - - - - - - - -
HLADNGJO_00188 1.94e-86 - - - - - - - -
HLADNGJO_00189 2.2e-66 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HLADNGJO_00190 5.51e-133 - - - K - - - Bacterial regulatory proteins, tetR family
HLADNGJO_00191 9.5e-52 - - - L ko:K07483 - ko00000 Transposase
HLADNGJO_00192 9.8e-28 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLADNGJO_00193 0.0 ybeC - - E - - - amino acid
HLADNGJO_00194 1.08e-287 - - - L - - - MULE transposase domain
HLADNGJO_00195 1.27e-09 - - - - - - - -
HLADNGJO_00196 6.51e-36 - - - - - - - -
HLADNGJO_00197 8.47e-155 - - - M - - - lysozyme activity
HLADNGJO_00201 7.07e-271 - - - S - - - peptidoglycan catabolic process
HLADNGJO_00203 3.63e-250 - - - S - - - peptidoglycan catabolic process
HLADNGJO_00204 2.01e-50 - - - S - - - Pfam:Phage_TAC_12
HLADNGJO_00205 3.25e-107 - - - S - - - Phage major tail protein 2
HLADNGJO_00206 6.25e-57 - - - - - - - -
HLADNGJO_00207 3.55e-56 - - - S - - - exonuclease activity
HLADNGJO_00208 7.85e-63 - - - S - - - Phage gp6-like head-tail connector protein
HLADNGJO_00209 2.23e-153 - - - - - - - -
HLADNGJO_00210 8.09e-86 - - - S - - - aminoacyl-tRNA ligase activity
HLADNGJO_00212 2.18e-175 - - - S - - - Phage Mu protein F like protein
HLADNGJO_00213 2.82e-262 - - - S - - - Phage portal protein, SPP1 Gp6-like
HLADNGJO_00214 6.32e-193 yqaT - - S ko:K06909 - ko00000 Phage terminase, large subunit
HLADNGJO_00215 6.82e-60 - - - L ko:K07474 - ko00000 Terminase small subunit
HLADNGJO_00224 1.5e-23 - - - S - - - Protein of unknown function (DUF1064)
HLADNGJO_00225 3.37e-14 - - - K - - - Cro/C1-type HTH DNA-binding domain
HLADNGJO_00229 9.04e-50 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HLADNGJO_00230 1.89e-63 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
HLADNGJO_00233 1.49e-89 - - - S - - - Single-strand binding protein family
HLADNGJO_00234 9.96e-210 - - - S - - - PDDEXK-like domain of unknown function (DUF3799)
HLADNGJO_00235 6.68e-216 - - - S - - - DNA metabolic process
HLADNGJO_00238 3.08e-05 - - - P - - - Helix-turn-helix domain
HLADNGJO_00239 7.65e-26 - - - K - - - Protein of unknown function (DUF739)
HLADNGJO_00240 9.09e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
HLADNGJO_00241 6.54e-41 - - - E - - - Zn peptidase
HLADNGJO_00244 7.1e-43 - - - - - - - -
HLADNGJO_00245 2.94e-156 int2 - - L - - - Belongs to the 'phage' integrase family
HLADNGJO_00247 4.52e-126 - - - - - - - -
HLADNGJO_00248 1.36e-100 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HLADNGJO_00249 9.05e-232 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HLADNGJO_00251 1.02e-19 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HLADNGJO_00252 1.94e-289 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_00253 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Aluminium induced protein
HLADNGJO_00254 5.38e-272 - - - L - - - Transposase and inactivated derivatives, IS30 family
HLADNGJO_00256 2.24e-11 - - - S - - - Bacterial transferase hexapeptide (six repeats)
HLADNGJO_00257 5.6e-153 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HLADNGJO_00258 6.09e-254 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
HLADNGJO_00259 2.47e-13 - - - K - - - transcriptional
HLADNGJO_00260 1.56e-67 - - - S - - - Sugar efflux transporter for intercellular exchange
HLADNGJO_00261 3.03e-74 - - - S - - - Antibiotic biosynthesis monooxygenase
HLADNGJO_00262 2.05e-59 - - - S - - - Protein conserved in bacteria
HLADNGJO_00263 4.67e-127 ydeQ - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
HLADNGJO_00264 3.32e-303 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_00265 1.47e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_00266 3.71e-194 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HLADNGJO_00267 7.82e-239 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLADNGJO_00268 1.64e-81 - - - S - - - Domain of unknown function (DUF4440)
HLADNGJO_00269 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLADNGJO_00270 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HLADNGJO_00271 1.3e-199 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HLADNGJO_00272 8.64e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLADNGJO_00273 2.87e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLADNGJO_00274 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLADNGJO_00275 3.97e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_00277 5.48e-70 - - - S - - - mazG nucleotide pyrophosphohydrolase
HLADNGJO_00278 5.34e-140 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HLADNGJO_00279 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLADNGJO_00280 1.15e-299 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLADNGJO_00281 9.97e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLADNGJO_00282 1.15e-208 - - - S - - - Tetratricopeptide repeat
HLADNGJO_00283 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLADNGJO_00284 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HLADNGJO_00285 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLADNGJO_00286 2.9e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HLADNGJO_00287 1.9e-235 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HLADNGJO_00288 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HLADNGJO_00289 8.66e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HLADNGJO_00290 7.3e-128 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HLADNGJO_00291 1.38e-252 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HLADNGJO_00292 2.51e-115 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLADNGJO_00293 1.27e-128 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HLADNGJO_00294 1.08e-62 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HLADNGJO_00295 1.45e-277 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HLADNGJO_00296 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HLADNGJO_00297 1.14e-176 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HLADNGJO_00298 1.55e-65 yktA - - S - - - Belongs to the UPF0223 family
HLADNGJO_00299 8.59e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLADNGJO_00300 2.18e-215 - - - L - - - PFAM Integrase catalytic region
HLADNGJO_00301 4.35e-30 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
HLADNGJO_00302 6.12e-98 - - - - - - - -
HLADNGJO_00303 8.83e-43 ykzG - - S - - - Belongs to the UPF0356 family
HLADNGJO_00304 2.95e-239 - - - I - - - Diacylglycerol kinase catalytic
HLADNGJO_00305 2.39e-98 - - - P - - - ArsC family
HLADNGJO_00306 1.55e-227 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLADNGJO_00307 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLADNGJO_00308 9.37e-159 - - - S - - - repeat protein
HLADNGJO_00309 1.11e-156 pgm6 - - G - - - phosphoglycerate mutase
HLADNGJO_00310 1.08e-218 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HLADNGJO_00311 0.0 - - - S - - - amidohydrolase
HLADNGJO_00312 1.7e-283 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLADNGJO_00313 7.86e-77 XK27_04120 - - S - - - Putative amino acid metabolism
HLADNGJO_00314 3.26e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLADNGJO_00315 2.68e-08 - - - - - - - -
HLADNGJO_00316 1.28e-126 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HLADNGJO_00317 9.99e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HLADNGJO_00318 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLADNGJO_00320 6.19e-143 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HLADNGJO_00321 7.15e-186 ylmH - - S - - - S4 domain protein
HLADNGJO_00322 7.27e-56 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HLADNGJO_00323 2.49e-100 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLADNGJO_00324 9.01e-294 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLADNGJO_00325 4.88e-300 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLADNGJO_00326 5.43e-193 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLADNGJO_00327 2.06e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLADNGJO_00328 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLADNGJO_00329 4.46e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLADNGJO_00330 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HLADNGJO_00331 5.28e-31 ftsL - - D - - - Cell division protein FtsL
HLADNGJO_00332 5.37e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLADNGJO_00333 7.65e-104 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HLADNGJO_00334 6.91e-76 - - - - - - - -
HLADNGJO_00335 4.5e-12 - - - S - - - Protein of unknown function (DUF4044)
HLADNGJO_00336 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HLADNGJO_00337 2.01e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLADNGJO_00338 3.9e-208 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HLADNGJO_00339 4.62e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HLADNGJO_00340 3.12e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HLADNGJO_00341 9.49e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLADNGJO_00342 5.24e-159 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HLADNGJO_00343 1.03e-147 yjbH - - Q - - - Thioredoxin
HLADNGJO_00344 2.06e-263 coiA - - S ko:K06198 - ko00000 Competence protein
HLADNGJO_00345 8.81e-152 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLADNGJO_00346 1.12e-90 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLADNGJO_00367 8.34e-101 - - - - - - - -
HLADNGJO_00368 1.01e-142 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HLADNGJO_00369 2.65e-21 - - - S - - - Protein of unknown function (DUF1461)
HLADNGJO_00370 8.33e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLADNGJO_00371 9.43e-127 yutD - - S - - - Protein of unknown function (DUF1027)
HLADNGJO_00372 2.73e-147 - - - S - - - Calcineurin-like phosphoesterase
HLADNGJO_00373 6.46e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLADNGJO_00374 3.57e-202 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HLADNGJO_00379 7.01e-51 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HLADNGJO_00380 0.000787 - - - K - - - ParB-like nuclease domain
HLADNGJO_00383 4.33e-116 - - - M - - - hydrolase, family 25
HLADNGJO_00384 8.54e-28 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
HLADNGJO_00387 3.33e-71 - - - - - - - -
HLADNGJO_00392 9.01e-38 - - - M - - - CHAP domain
HLADNGJO_00393 1.65e-150 - - - S - - - Phage tail protein
HLADNGJO_00394 0.0 - - - S - - - peptidoglycan catabolic process
HLADNGJO_00395 7.6e-54 - - - S - - - Bacteriophage Gp15 protein
HLADNGJO_00397 8.66e-15 - - - N - - - domain, Protein
HLADNGJO_00398 2.94e-12 - - - S - - - Minor capsid protein from bacteriophage
HLADNGJO_00399 3.22e-25 - - - S - - - Minor capsid protein
HLADNGJO_00400 3.76e-39 - - - S - - - Minor capsid protein
HLADNGJO_00402 2.02e-106 - - - - - - - -
HLADNGJO_00403 1.57e-30 - - - S - - - Phage minor structural protein GP20
HLADNGJO_00404 1.01e-140 - - - S - - - Phage minor capsid protein 2
HLADNGJO_00405 5.1e-189 - - - S - - - Phage portal protein, SPP1 Gp6-like
HLADNGJO_00406 4.6e-218 - - - S - - - Pfam:Terminase_3C
HLADNGJO_00407 5.89e-18 - - - S - - - Terminase small subunit
HLADNGJO_00408 1.9e-36 - - - S - - - Terminase small subunit
HLADNGJO_00410 9.17e-63 - - - K - - - Domain of unknown function (DUF4417)
HLADNGJO_00416 7.16e-101 - - - Q - - - DNA (cytosine-5-)-methyltransferase activity
HLADNGJO_00421 2.82e-51 rusA - - L - - - Endodeoxyribonuclease RusA
HLADNGJO_00426 2.9e-53 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HLADNGJO_00427 9.34e-79 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
HLADNGJO_00428 4.73e-20 - - - S - - - Single-strand binding protein family
HLADNGJO_00429 6.01e-211 - - - S - - - PDDEXK-like domain of unknown function (DUF3799)
HLADNGJO_00430 2.88e-225 - - - S - - - DNA metabolic process
HLADNGJO_00436 3.44e-33 - - - - - - - -
HLADNGJO_00437 1.25e-169 - - - K - - - Phage regulatory protein
HLADNGJO_00438 2.88e-20 - - - K - - - Helix-turn-helix XRE-family like proteins
HLADNGJO_00439 4.37e-29 - - - K - - - sequence-specific DNA binding
HLADNGJO_00442 1.81e-31 - - - - - - - -
HLADNGJO_00443 1.34e-280 - - - S - - - Recombinase
HLADNGJO_00445 2.13e-212 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HLADNGJO_00446 1.33e-228 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HLADNGJO_00447 0.0 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
HLADNGJO_00448 1.87e-110 - - - M - - - PFAM NLP P60 protein
HLADNGJO_00449 5.01e-172 yebC - - K - - - Transcriptional regulatory protein
HLADNGJO_00450 1.4e-181 - - - - - - - -
HLADNGJO_00451 5.94e-238 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HLADNGJO_00452 1.26e-271 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HLADNGJO_00453 4.62e-92 - - - - - - - -
HLADNGJO_00454 5.14e-68 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLADNGJO_00455 4.32e-200 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HLADNGJO_00456 1.75e-193 - - - S - - - haloacid dehalogenase-like hydrolase
HLADNGJO_00457 1.62e-204 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_00458 3.33e-123 - - - S ko:K07095 - ko00000 Phosphoesterase
HLADNGJO_00459 2.65e-140 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLADNGJO_00460 6.11e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HLADNGJO_00461 2.49e-123 yslB - - S - - - Protein of unknown function (DUF2507)
HLADNGJO_00462 8.83e-285 - - - P - - - Chloride transporter, ClC family
HLADNGJO_00463 1.66e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HLADNGJO_00464 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLADNGJO_00465 2.23e-119 cvpA - - S - - - Colicin V production protein
HLADNGJO_00466 3.2e-211 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLADNGJO_00467 3.99e-55 yrzB - - S - - - Belongs to the UPF0473 family
HLADNGJO_00468 4.97e-97 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLADNGJO_00469 1.06e-57 yrzL - - S - - - Belongs to the UPF0297 family
HLADNGJO_00470 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLADNGJO_00471 8.44e-301 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLADNGJO_00472 3.41e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HLADNGJO_00473 1.11e-68 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HLADNGJO_00474 1.26e-225 - 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 queuine tRNA-ribosyltransferase activity
HLADNGJO_00475 8.49e-242 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLADNGJO_00476 1.77e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLADNGJO_00477 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLADNGJO_00478 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLADNGJO_00479 2.27e-305 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HLADNGJO_00480 7.88e-245 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLADNGJO_00481 8.95e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HLADNGJO_00482 1.79e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLADNGJO_00483 2.69e-150 - - - S - - - Helix-turn-helix domain
HLADNGJO_00484 0.0 ymfH - - S - - - Peptidase M16
HLADNGJO_00485 3.68e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
HLADNGJO_00486 3.88e-204 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HLADNGJO_00487 4.86e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_00488 3.81e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HLADNGJO_00489 9.04e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HLADNGJO_00490 1.37e-187 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HLADNGJO_00491 1.34e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HLADNGJO_00492 5.3e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
HLADNGJO_00493 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HLADNGJO_00494 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLADNGJO_00495 3.11e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLADNGJO_00499 2.16e-50 - - - S - - - zinc-ribbon domain
HLADNGJO_00500 1.61e-52 - - - - - - - -
HLADNGJO_00503 3.88e-50 - - - M - - - LysM domain
HLADNGJO_00504 3.17e-260 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HLADNGJO_00505 3.95e-278 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
HLADNGJO_00506 2.03e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLADNGJO_00507 5.83e-273 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HLADNGJO_00508 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLADNGJO_00509 5.1e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLADNGJO_00513 1.62e-268 - - - M - - - hydrolase, family 25
HLADNGJO_00514 3.54e-38 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
HLADNGJO_00520 1.51e-49 - - - - - - - -
HLADNGJO_00525 1.34e-33 - - - M - - - CHAP domain
HLADNGJO_00526 2.14e-98 - - - S - - - Phage tail protein
HLADNGJO_00527 2.23e-154 - - - S - - - peptidoglycan catabolic process
HLADNGJO_00528 1.07e-45 - - - S - - - Bacteriophage Gp15 protein
HLADNGJO_00529 9.57e-07 - - - - - - - -
HLADNGJO_00530 1.4e-37 - - - N - - - Belongs to the glycosyl hydrolase family 6
HLADNGJO_00532 6.05e-23 - - - S - - - Minor capsid protein
HLADNGJO_00533 3.32e-38 - - - S - - - Minor capsid protein
HLADNGJO_00535 4.44e-104 - - - - - - - -
HLADNGJO_00536 3.68e-24 - - - S - - - Phage minor structural protein GP20
HLADNGJO_00537 1.88e-115 - - - S - - - Phage minor capsid protein 2
HLADNGJO_00538 1.18e-184 - - - S - - - Phage portal protein, SPP1 Gp6-like
HLADNGJO_00539 1.14e-208 - - - S - - - Pfam:Terminase_3C
HLADNGJO_00540 1.57e-60 - - - - - - - -
HLADNGJO_00541 1.08e-51 - - - S - - - RloB-like protein
HLADNGJO_00542 5.35e-149 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
HLADNGJO_00544 1.18e-291 - - - L - - - MULE transposase domain
HLADNGJO_00546 7.69e-33 - - - L - - - Psort location Cytoplasmic, score
HLADNGJO_00547 9.59e-107 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLADNGJO_00548 2.82e-198 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HLADNGJO_00549 1.99e-225 - - - L ko:K07455 - ko00000,ko03400 RecT family
HLADNGJO_00554 7.56e-80 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
HLADNGJO_00555 8e-08 - - - K - - - Helix-turn-helix XRE-family like proteins
HLADNGJO_00556 2.86e-25 - - - K - - - Helix-turn-helix domain
HLADNGJO_00560 8.41e-41 - - - S - - - Bacterial PH domain
HLADNGJO_00561 3.23e-270 int3 - - L - - - Belongs to the 'phage' integrase family
HLADNGJO_00563 1.25e-15 - - - S - - - YjcQ protein
HLADNGJO_00564 7.09e-189 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLADNGJO_00565 2.3e-173 - - - S - - - Membrane
HLADNGJO_00566 1.52e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
HLADNGJO_00567 8.04e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HLADNGJO_00568 4.72e-301 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HLADNGJO_00570 6.08e-107 uspA - - T - - - universal stress protein
HLADNGJO_00571 1.7e-195 - - - K - - - Helix-turn-helix XRE-family like proteins
HLADNGJO_00572 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_00573 5.85e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HLADNGJO_00574 9.42e-232 - - - S - - - Protein of unknown function (DUF2785)
HLADNGJO_00576 5.09e-283 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HLADNGJO_00577 7.67e-43 - - - S - - - Protein of unknown function (DUF2969)
HLADNGJO_00578 9.42e-234 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HLADNGJO_00579 4.64e-276 - - - M - - - EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HLADNGJO_00580 8.07e-40 - - - S - - - Protein of unknown function (DUF1146)
HLADNGJO_00581 1.19e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HLADNGJO_00582 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLADNGJO_00583 1.78e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLADNGJO_00584 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLADNGJO_00585 1.23e-119 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLADNGJO_00586 5.83e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLADNGJO_00587 2.13e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLADNGJO_00588 5.66e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HLADNGJO_00589 2.12e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HLADNGJO_00590 2.24e-164 yibF - - S - - - overlaps another CDS with the same product name
HLADNGJO_00591 2e-252 yibE - - S - - - overlaps another CDS with the same product name
HLADNGJO_00592 3.86e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLADNGJO_00593 5.2e-293 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLADNGJO_00594 8.28e-251 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLADNGJO_00595 3.18e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLADNGJO_00596 5.36e-208 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLADNGJO_00597 1.78e-139 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HLADNGJO_00598 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HLADNGJO_00599 7.49e-181 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
HLADNGJO_00600 2.31e-63 - - - - - - - -
HLADNGJO_00601 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLADNGJO_00602 2.65e-245 ampC - - V - - - Beta-lactamase
HLADNGJO_00603 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HLADNGJO_00604 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_00605 1.02e-102 - - - K - - - Winged helix-turn-helix DNA-binding
HLADNGJO_00606 3.24e-10 - - - - - - - -
HLADNGJO_00608 2.67e-75 - - - - - - - -
HLADNGJO_00610 6.37e-169 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
HLADNGJO_00611 5.46e-186 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLADNGJO_00612 3.74e-205 yvgN - - S - - - Aldo keto reductase
HLADNGJO_00613 2.11e-157 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HLADNGJO_00614 5e-111 - - - K - - - GNAT family
HLADNGJO_00616 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HLADNGJO_00617 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
HLADNGJO_00618 1.88e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
HLADNGJO_00619 1.12e-64 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_00620 3.02e-126 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_00621 1.37e-290 - - - L - - - MULE transposase domain
HLADNGJO_00623 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Xylulose kinase
HLADNGJO_00624 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HLADNGJO_00625 0.0 xylT - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLADNGJO_00626 9.01e-276 xylR - - GK - - - ROK family
HLADNGJO_00627 5.03e-196 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HLADNGJO_00628 0.0 yclK - - T - - - Histidine kinase
HLADNGJO_00629 2.8e-170 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HLADNGJO_00631 4.47e-314 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_00632 1.8e-76 manO - - S - - - Domain of unknown function (DUF956)
HLADNGJO_00633 1.37e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HLADNGJO_00634 3.38e-164 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HLADNGJO_00635 2.22e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HLADNGJO_00636 1.5e-231 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HLADNGJO_00637 8.77e-117 - - - K - - - Domain of unknown function (DUF1836)
HLADNGJO_00638 4.46e-191 yitS - - S - - - EDD domain protein, DegV family
HLADNGJO_00639 3.15e-163 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HLADNGJO_00640 1.12e-211 - - - K - - - LysR substrate binding domain
HLADNGJO_00641 6.96e-222 - - - S - - - Conserved hypothetical protein 698
HLADNGJO_00642 4.55e-111 lytE - - M - - - Lysin motif
HLADNGJO_00643 2.13e-193 XK27_02985 - - S - - - Sucrose-6F-phosphate phosphohydrolase
HLADNGJO_00644 5.83e-263 oatA - - I - - - Acyltransferase
HLADNGJO_00645 2.55e-68 - - - - - - - -
HLADNGJO_00646 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLADNGJO_00647 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLADNGJO_00648 2.4e-151 ybbR - - S - - - YbbR-like protein
HLADNGJO_00649 1.61e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLADNGJO_00650 2.34e-212 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HLADNGJO_00651 4e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HLADNGJO_00652 5.51e-118 - - - K - - - Acetyltransferase (GNAT) domain
HLADNGJO_00653 2.44e-104 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HLADNGJO_00654 9.74e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HLADNGJO_00655 5.28e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLADNGJO_00656 2.36e-139 - - - - - - - -
HLADNGJO_00657 4.66e-110 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLADNGJO_00658 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLADNGJO_00659 6.82e-46 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HLADNGJO_00660 0.0 eriC - - P ko:K03281 - ko00000 chloride
HLADNGJO_00661 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HLADNGJO_00662 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLADNGJO_00663 2.92e-184 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLADNGJO_00664 4.22e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HLADNGJO_00665 2.64e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLADNGJO_00666 3.82e-23 - - - - - - - -
HLADNGJO_00670 2.96e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLADNGJO_00671 4.88e-154 - 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HLADNGJO_00672 2.34e-214 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HLADNGJO_00673 2.33e-239 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HLADNGJO_00674 3.72e-204 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HLADNGJO_00675 1.52e-262 - - - - - - - -
HLADNGJO_00676 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLADNGJO_00677 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLADNGJO_00679 1.24e-145 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HLADNGJO_00680 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HLADNGJO_00681 4.18e-176 - - - S - - - haloacid dehalogenase-like hydrolase
HLADNGJO_00682 1.59e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HLADNGJO_00683 2.39e-254 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HLADNGJO_00684 7.3e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HLADNGJO_00685 2.83e-199 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HLADNGJO_00686 4.74e-166 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLADNGJO_00687 1.21e-212 - - - L - - - PFAM Integrase catalytic region
HLADNGJO_00688 4.35e-30 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
HLADNGJO_00689 2.23e-101 yphH - - S - - - Cupin domain
HLADNGJO_00690 6.21e-241 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLADNGJO_00691 2.97e-287 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HLADNGJO_00692 6.89e-185 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HLADNGJO_00693 7.64e-220 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HLADNGJO_00694 9.09e-236 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HLADNGJO_00695 2.64e-209 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLADNGJO_00696 1.68e-227 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLADNGJO_00697 4.15e-69 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HLADNGJO_00698 1.97e-70 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
HLADNGJO_00699 1.45e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLADNGJO_00700 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLADNGJO_00701 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_00702 4.64e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLADNGJO_00703 1.07e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HLADNGJO_00704 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HLADNGJO_00705 1.7e-148 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HLADNGJO_00706 6.81e-40 - - - - - - - -
HLADNGJO_00707 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_00708 0.0 ydaO - - E - - - amino acid
HLADNGJO_00709 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLADNGJO_00710 5.71e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLADNGJO_00711 8.05e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLADNGJO_00712 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HLADNGJO_00713 1.04e-224 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLADNGJO_00714 6.8e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HLADNGJO_00715 1.55e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HLADNGJO_00716 2.69e-181 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HLADNGJO_00717 2.25e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLADNGJO_00718 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HLADNGJO_00719 1.13e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLADNGJO_00720 3.46e-94 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLADNGJO_00721 1.32e-291 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLADNGJO_00722 2.67e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HLADNGJO_00723 2.76e-219 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HLADNGJO_00724 4.18e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLADNGJO_00725 5.58e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLADNGJO_00726 2.27e-98 - - - K - - - Transcriptional regulator, MarR family
HLADNGJO_00727 3.83e-100 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLADNGJO_00729 2.11e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLADNGJO_00730 1.93e-143 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HLADNGJO_00731 2.38e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HLADNGJO_00732 1.61e-274 arcT - - E - - - Aminotransferase
HLADNGJO_00733 8.37e-282 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HLADNGJO_00734 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HLADNGJO_00735 3.45e-305 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HLADNGJO_00736 4.08e-218 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HLADNGJO_00737 2.08e-239 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLADNGJO_00738 7.82e-203 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
HLADNGJO_00739 8.55e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HLADNGJO_00740 6.78e-221 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HLADNGJO_00741 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HLADNGJO_00742 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HLADNGJO_00743 4.02e-189 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HLADNGJO_00744 2.83e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLADNGJO_00745 2.47e-74 yabA - - L - - - Involved in initiation control of chromosome replication
HLADNGJO_00746 2.36e-247 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HLADNGJO_00747 7.84e-71 yaaQ - - S - - - Cyclic-di-AMP receptor
HLADNGJO_00748 2.41e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLADNGJO_00749 2.06e-28 - - - S - - - Protein of unknown function (DUF2508)
HLADNGJO_00750 6.48e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLADNGJO_00751 3.97e-60 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLADNGJO_00752 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLADNGJO_00754 3.69e-113 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLADNGJO_00755 6.56e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HLADNGJO_00756 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLADNGJO_00757 8.93e-250 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLADNGJO_00758 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HLADNGJO_00759 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HLADNGJO_00760 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HLADNGJO_00761 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HLADNGJO_00762 4.17e-237 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HLADNGJO_00763 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HLADNGJO_00764 8.24e-71 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLADNGJO_00765 3.88e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLADNGJO_00766 2.22e-312 steT - - E ko:K03294 - ko00000 amino acid
HLADNGJO_00767 1.96e-156 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLADNGJO_00768 3.34e-68 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLADNGJO_00769 8.34e-127 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HLADNGJO_00770 2.04e-31 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLADNGJO_00771 7.09e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HLADNGJO_00772 5.57e-135 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HLADNGJO_00773 1.01e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLADNGJO_00774 1.25e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLADNGJO_00775 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HLADNGJO_00776 9.63e-130 ywlG - - S - - - Belongs to the UPF0340 family
HLADNGJO_00777 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLADNGJO_00778 4.73e-265 yacL - - S - - - domain protein
HLADNGJO_00779 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLADNGJO_00780 3.55e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HLADNGJO_00781 6.52e-73 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HLADNGJO_00782 5.86e-157 - 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLADNGJO_00783 3.45e-144 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HLADNGJO_00784 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HLADNGJO_00785 3.77e-214 - - - I - - - alpha/beta hydrolase fold
HLADNGJO_00786 7.78e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLADNGJO_00787 1.25e-212 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HLADNGJO_00788 9.16e-241 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HLADNGJO_00789 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HLADNGJO_00791 6.97e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HLADNGJO_00792 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HLADNGJO_00793 2.71e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLADNGJO_00794 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLADNGJO_00795 8.7e-166 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HLADNGJO_00796 1.56e-170 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HLADNGJO_00797 5.68e-150 - - - - - - - -
HLADNGJO_00800 2.36e-212 - - - S - - - Calcineurin-like phosphoesterase
HLADNGJO_00801 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HLADNGJO_00802 3.91e-258 - - - D - - - nuclear chromosome segregation
HLADNGJO_00803 2.89e-186 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_00804 4.87e-89 - - - L - - - PFAM transposase, IS4 family protein
HLADNGJO_00806 3.65e-61 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_00807 2.87e-306 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
HLADNGJO_00808 2.83e-198 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HLADNGJO_00809 5.85e-225 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HLADNGJO_00810 1.13e-77 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_00813 8.34e-101 - - - - - - - -
HLADNGJO_00816 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HLADNGJO_00817 2.64e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLADNGJO_00818 3.89e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLADNGJO_00819 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLADNGJO_00820 5.21e-126 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HLADNGJO_00821 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLADNGJO_00822 1.65e-113 yabR - - J ko:K07571 - ko00000 RNA binding
HLADNGJO_00823 5.88e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HLADNGJO_00824 2.47e-53 yabO - - J - - - S4 domain protein
HLADNGJO_00825 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLADNGJO_00826 1.32e-130 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLADNGJO_00827 4.51e-148 - - - S - - - (CBS) domain
HLADNGJO_00828 7.09e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HLADNGJO_00829 6.25e-268 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLADNGJO_00830 1.18e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLADNGJO_00831 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLADNGJO_00832 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLADNGJO_00833 1.34e-202 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HLADNGJO_00834 1.66e-119 lemA - - S ko:K03744 - ko00000 LemA family
HLADNGJO_00835 7.41e-61 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLADNGJO_00836 1.32e-158 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HLADNGJO_00837 1.21e-36 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
HLADNGJO_00838 3.85e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HLADNGJO_00839 4.36e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLADNGJO_00840 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLADNGJO_00841 2.16e-97 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLADNGJO_00842 5.23e-97 ywiB - - S - - - Domain of unknown function (DUF1934)
HLADNGJO_00843 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HLADNGJO_00844 1.01e-184 yidA - - S - - - hydrolase
HLADNGJO_00845 6.2e-77 - - - - - - - -
HLADNGJO_00846 6.73e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLADNGJO_00847 9.91e-302 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLADNGJO_00848 2.13e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HLADNGJO_00849 2.81e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
HLADNGJO_00850 1.98e-123 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HLADNGJO_00851 4.92e-213 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HLADNGJO_00852 4.04e-205 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLADNGJO_00853 6.18e-206 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLADNGJO_00854 6.51e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLADNGJO_00855 3.29e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HLADNGJO_00856 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLADNGJO_00857 2.01e-208 yunF - - F - - - Protein of unknown function DUF72
HLADNGJO_00858 2.38e-272 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HLADNGJO_00859 1.9e-164 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HLADNGJO_00860 9.16e-240 - - - - - - - -
HLADNGJO_00861 5.79e-288 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HLADNGJO_00862 7.95e-222 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HLADNGJO_00863 0.0 - - - L - - - DNA helicase
HLADNGJO_00864 6.37e-259 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLADNGJO_00865 9.46e-199 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HLADNGJO_00867 3.03e-181 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HLADNGJO_00869 4.97e-120 - - - K - - - Transcriptional regulator
HLADNGJO_00870 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HLADNGJO_00871 5.19e-251 adh1 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HLADNGJO_00872 2.85e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_00873 8.15e-108 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_00874 1.06e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
HLADNGJO_00875 2.81e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HLADNGJO_00876 1.58e-159 - - - C - - - nitroreductase
HLADNGJO_00877 3.02e-226 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HLADNGJO_00878 3.06e-157 cpkA 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Amino acid kinase family
HLADNGJO_00879 0.000595 - - - S - - - Protein of unknown function (DUF2877)
HLADNGJO_00881 1.04e-53 - - - C - - - Protein of unknown function (DUF1116)
HLADNGJO_00882 3.99e-85 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
HLADNGJO_00883 2.12e-78 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
HLADNGJO_00884 1.39e-232 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLADNGJO_00885 8.34e-101 - - - - - - - -
HLADNGJO_00886 2e-203 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HLADNGJO_00887 1.05e-49 - - - - - - - -
HLADNGJO_00888 5.93e-26 - - - - - - - -
HLADNGJO_00889 9.56e-303 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
HLADNGJO_00890 4.45e-181 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_00891 1.04e-199 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLADNGJO_00892 7.99e-196 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HLADNGJO_00893 4.6e-130 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
HLADNGJO_00894 0.0 - - - M - - - Iron Transport-associated domain
HLADNGJO_00895 3.23e-118 - - - - - - - -
HLADNGJO_00896 8.58e-71 - 4.1.1.44 - O ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HLADNGJO_00897 2.02e-116 - - - P - - - Cadmium resistance transporter
HLADNGJO_00898 2.62e-07 - - - C - - - Aldo/keto reductase family
HLADNGJO_00900 5.11e-06 - - - S - - - CsbD-like
HLADNGJO_00901 4.22e-50 - - - C - - - Aldo keto reductase
HLADNGJO_00902 4.56e-06 - - - K - - - LysR substrate binding domain
HLADNGJO_00903 5.7e-56 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HLADNGJO_00905 2.48e-135 - 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha/beta hydrolase family
HLADNGJO_00906 3.17e-156 pnb - - C - - - nitroreductase
HLADNGJO_00908 2.85e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_00909 8.15e-108 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_00911 8.34e-101 - - - - - - - -
HLADNGJO_00912 6.87e-117 yejD 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 nucleoside 2-deoxyribosyltransferase
HLADNGJO_00913 6.23e-36 - - - EGP - - - Major Facilitator
HLADNGJO_00914 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HLADNGJO_00915 2.79e-69 - - - S - - - Cupredoxin-like domain
HLADNGJO_00916 4.36e-67 - - - S - - - Cupredoxin-like domain
HLADNGJO_00917 2.47e-227 - - - - - - - -
HLADNGJO_00918 6.98e-286 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HLADNGJO_00919 1.15e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLADNGJO_00920 1.66e-308 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HLADNGJO_00921 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HLADNGJO_00922 1.13e-139 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLADNGJO_00923 4.8e-251 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HLADNGJO_00924 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLADNGJO_00925 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLADNGJO_00926 4.87e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLADNGJO_00927 1.36e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLADNGJO_00928 1.51e-174 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HLADNGJO_00929 8.78e-15 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
HLADNGJO_00930 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HLADNGJO_00931 3.8e-219 hrpQ 4.6.1.1 - T ko:K01768,ko:K03220,ko:K10914 ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111 ko00000,ko00001,ko00002,ko01000,ko02044,ko03000 histone H2A K63-linked ubiquitination
HLADNGJO_00932 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLADNGJO_00933 1.44e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLADNGJO_00934 1.17e-105 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLADNGJO_00935 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HLADNGJO_00936 9.91e-224 ydbI - - K - - - AI-2E family transporter
HLADNGJO_00937 1.4e-11 - - - K - - - Bacterial regulatory proteins, tetR family
HLADNGJO_00938 1.66e-32 - - - K - - - transcriptional regulator
HLADNGJO_00939 2.82e-86 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_00940 5.09e-161 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_00941 7.25e-87 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_00942 4.72e-303 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_00943 1.42e-291 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HLADNGJO_00944 7.7e-130 - - - S ko:K07002 - ko00000 Serine hydrolase
HLADNGJO_00945 3.16e-78 - - - S - - - branched-chain amino acid
HLADNGJO_00946 8.39e-178 - - - E - - - AzlC protein
HLADNGJO_00947 4.61e-267 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HLADNGJO_00948 2.18e-267 hpk31 - - T - - - Histidine kinase
HLADNGJO_00949 1.44e-156 vanR - - K - - - response regulator
HLADNGJO_00950 9.58e-122 - - - S ko:K09705 - ko00000 Cupin superfamily (DUF985)
HLADNGJO_00951 3.08e-53 - - - L - - - MULE transposase domain
HLADNGJO_00952 5.95e-05 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
HLADNGJO_00953 6.28e-271 - - - L - - - Transposase and inactivated derivatives, IS30 family
HLADNGJO_00954 1.11e-106 cps2J - - S - - - Polysaccharide biosynthesis protein
HLADNGJO_00955 8.73e-56 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HLADNGJO_00956 6.26e-169 cps4I - - M - - - Glycosyltransferase like family 2
HLADNGJO_00957 5.96e-218 - - - - - - - -
HLADNGJO_00958 8.85e-159 cps4G - - M - - - Glycosyltransferase Family 4
HLADNGJO_00959 8.67e-237 cps4F - - M - - - Glycosyl transferases group 1
HLADNGJO_00960 3.59e-121 tuaA - - M - - - Bacterial sugar transferase
HLADNGJO_00961 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_00962 5.27e-107 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HLADNGJO_00963 9.33e-177 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HLADNGJO_00964 1.36e-146 ywqD - - D - - - Capsular exopolysaccharide family
HLADNGJO_00965 5.79e-171 epsB - - M - - - biosynthesis protein
HLADNGJO_00966 4.94e-222 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HLADNGJO_00967 6.97e-264 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLADNGJO_00968 6.25e-171 - - - S - - - Protein of unknown function (DUF1129)
HLADNGJO_00969 7.12e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLADNGJO_00970 6.22e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HLADNGJO_00971 2.51e-187 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HLADNGJO_00972 2.32e-209 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HLADNGJO_00973 5.01e-171 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HLADNGJO_00974 2.31e-185 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HLADNGJO_00975 8.94e-272 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
HLADNGJO_00976 3.64e-316 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HLADNGJO_00977 1.56e-175 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_00978 3.64e-284 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLADNGJO_00980 4.91e-240 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HLADNGJO_00982 2.24e-300 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLADNGJO_00983 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HLADNGJO_00984 1.05e-277 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLADNGJO_00985 1.69e-09 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HLADNGJO_00986 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLADNGJO_00987 3.06e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HLADNGJO_00988 3.78e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLADNGJO_00989 4.8e-310 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLADNGJO_00990 7.39e-106 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HLADNGJO_00991 6.26e-309 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLADNGJO_00992 2.85e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_00993 1.16e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_00994 2.41e-279 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HLADNGJO_00995 3.68e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLADNGJO_00996 2.44e-244 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLADNGJO_00997 2.71e-197 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HLADNGJO_00998 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HLADNGJO_00999 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HLADNGJO_01000 2.21e-61 - - - - - - - -
HLADNGJO_01001 2.9e-21 gntT - - EG - - - gluconate transmembrane transporter activity
HLADNGJO_01002 6.19e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLADNGJO_01003 5.85e-169 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLADNGJO_01004 8.04e-124 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLADNGJO_01005 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HLADNGJO_01006 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLADNGJO_01007 2.81e-212 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLADNGJO_01008 1.58e-122 - - - K - - - transcriptional regulator
HLADNGJO_01009 1.13e-166 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HLADNGJO_01010 2.15e-242 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HLADNGJO_01011 3.67e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HLADNGJO_01012 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HLADNGJO_01013 1.26e-210 - - - C - - - Aldo keto reductase
HLADNGJO_01014 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HLADNGJO_01015 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HLADNGJO_01016 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLADNGJO_01017 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
HLADNGJO_01018 2.33e-47 - - - - - - - -
HLADNGJO_01019 2.69e-275 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HLADNGJO_01020 1.02e-233 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLADNGJO_01021 7.51e-22 - - - D ko:K06889 - ko00000 Alpha beta
HLADNGJO_01022 4.31e-173 - - - D ko:K06889 - ko00000 Alpha beta
HLADNGJO_01023 1.04e-244 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLADNGJO_01024 2.14e-72 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 transmembrane transport
HLADNGJO_01025 6.48e-55 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 transmembrane transport
HLADNGJO_01026 7.69e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HLADNGJO_01027 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HLADNGJO_01028 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HLADNGJO_01029 1.09e-223 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HLADNGJO_01030 3.03e-94 ywnA - - K - - - Transcriptional regulator
HLADNGJO_01031 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLADNGJO_01032 9.52e-270 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HLADNGJO_01033 6.41e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HLADNGJO_01034 2.29e-182 yycI - - S - - - YycH protein
HLADNGJO_01035 3.63e-306 yycH - - S - - - YycH protein
HLADNGJO_01036 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLADNGJO_01037 4.31e-167 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HLADNGJO_01040 1.97e-64 - - - - - - - -
HLADNGJO_01041 6.24e-268 - - - E - - - Major Facilitator Superfamily
HLADNGJO_01042 4.28e-309 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HLADNGJO_01043 2.63e-99 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HLADNGJO_01044 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HLADNGJO_01045 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLADNGJO_01046 2.67e-164 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLADNGJO_01047 6.02e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HLADNGJO_01048 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLADNGJO_01049 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLADNGJO_01050 2.5e-258 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLADNGJO_01051 1.45e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HLADNGJO_01052 5.29e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLADNGJO_01053 9.49e-317 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLADNGJO_01054 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HLADNGJO_01055 6.22e-74 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLADNGJO_01056 4.99e-187 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLADNGJO_01057 5.25e-198 jag - - S ko:K06346 - ko00000 R3H domain protein
HLADNGJO_01058 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLADNGJO_01059 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLADNGJO_01060 2.44e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_01061 5.98e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_01062 2.07e-75 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLADNGJO_01063 4.35e-284 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HLADNGJO_01064 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HLADNGJO_01065 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLADNGJO_01066 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLADNGJO_01067 1.16e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HLADNGJO_01068 7.62e-216 - - - L - - - PFAM Integrase catalytic region
HLADNGJO_01069 3.8e-31 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
HLADNGJO_01070 6.82e-73 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_01071 9.75e-299 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_01072 1.46e-207 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HLADNGJO_01073 8.27e-111 - - - L - - - nuclease
HLADNGJO_01074 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLADNGJO_01075 3.46e-68 - - - - - - - -
HLADNGJO_01076 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HLADNGJO_01077 5.52e-241 - - - E - - - Zinc-binding dehydrogenase
HLADNGJO_01078 3.89e-139 - - - K - - - Bacterial regulatory proteins, tetR family
HLADNGJO_01079 2.85e-209 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HLADNGJO_01080 2.9e-158 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_01081 7.5e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HLADNGJO_01082 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_01083 3.55e-61 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HLADNGJO_01084 3.29e-315 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLADNGJO_01085 5.18e-182 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HLADNGJO_01086 1.11e-35 - - - - - - - -
HLADNGJO_01087 2.79e-137 - - - - - - - -
HLADNGJO_01088 6.55e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLADNGJO_01089 3.04e-140 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HLADNGJO_01090 8.76e-73 - - - - - - - -
HLADNGJO_01091 2.32e-161 yrkL - - S - - - Flavodoxin-like fold
HLADNGJO_01093 7.89e-85 yeaO - - S - - - Protein of unknown function, DUF488
HLADNGJO_01094 2e-150 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HLADNGJO_01095 2.43e-264 - - - S - - - associated with various cellular activities
HLADNGJO_01096 2.24e-273 - - - S - - - Putative metallopeptidase domain
HLADNGJO_01097 8.5e-61 - - - - - - - -
HLADNGJO_01098 1.73e-290 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HLADNGJO_01099 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HLADNGJO_01100 2.01e-119 ymdB - - S - - - Macro domain protein
HLADNGJO_01101 8.79e-188 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HLADNGJO_01102 5.18e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLADNGJO_01103 4.23e-217 - 1.1.1.399, 1.1.1.95 - CH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLADNGJO_01104 9.08e-71 - - - - - - - -
HLADNGJO_01105 1.09e-180 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HLADNGJO_01106 3.51e-154 - - - U ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLADNGJO_01107 2.05e-174 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_01108 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_01109 1.21e-48 - - - - - - - -
HLADNGJO_01110 2.44e-125 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HLADNGJO_01111 3.38e-185 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HLADNGJO_01112 1.63e-232 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
HLADNGJO_01113 2.95e-285 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLADNGJO_01114 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HLADNGJO_01115 8.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HLADNGJO_01116 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HLADNGJO_01117 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HLADNGJO_01118 2.77e-157 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_01119 1.16e-156 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_01120 4.43e-118 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_01121 1.23e-12 - - - L - - - Helix-turn-helix domain
HLADNGJO_01122 8.85e-133 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HLADNGJO_01123 4.11e-150 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_01124 3.46e-225 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HLADNGJO_01125 0.0 dld 1.1.5.12 - C ko:K03777 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-lactate dehydrogenase, membrane binding
HLADNGJO_01126 2.72e-189 - - - L - - - 4.5 Transposon and IS
HLADNGJO_01127 1.9e-39 - - - L ko:K07483 - ko00000 Transposase
HLADNGJO_01128 1.76e-160 - - - S - - - Membrane
HLADNGJO_01129 1.29e-298 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLADNGJO_01130 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HLADNGJO_01131 4.82e-229 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HLADNGJO_01132 9.39e-181 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLADNGJO_01133 1.07e-103 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HLADNGJO_01134 2.13e-106 usp5 - - T - - - universal stress protein
HLADNGJO_01135 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLADNGJO_01136 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLADNGJO_01137 2.96e-265 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HLADNGJO_01138 1.81e-98 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
HLADNGJO_01139 3.05e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HLADNGJO_01140 0.0 yhdP - - S - - - Transporter associated domain
HLADNGJO_01141 3.4e-116 - - - GM - - - epimerase
HLADNGJO_01142 1.7e-112 - - - K - - - Domain of unknown function (DUF1836)
HLADNGJO_01143 1.25e-197 - - - G - - - Xylose isomerase domain protein TIM barrel
HLADNGJO_01144 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HLADNGJO_01145 3.78e-167 - - - - - - - -
HLADNGJO_01146 4.23e-115 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLADNGJO_01147 3.81e-169 gntR - - K - - - UbiC transcription regulator-associated domain protein
HLADNGJO_01148 4.33e-191 - - - S - - - haloacid dehalogenase-like hydrolase
HLADNGJO_01149 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HLADNGJO_01151 0.0 potE - - E - - - Amino Acid
HLADNGJO_01152 3.91e-178 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HLADNGJO_01153 3.2e-199 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLADNGJO_01154 2.15e-203 - - - - - - - -
HLADNGJO_01155 3.61e-245 - 2.7.1.53 - G ko:K00880 ko00040,ko00053,map00040,map00053 ko00000,ko00001,ko01000 Xylulose kinase
HLADNGJO_01156 6.57e-180 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
HLADNGJO_01157 1.76e-174 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HLADNGJO_01158 1.19e-66 - - - G - - - Xylose isomerase domain protein TIM barrel
HLADNGJO_01159 3.34e-303 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
HLADNGJO_01160 1.48e-186 - - - S - - - Amidohydrolase
HLADNGJO_01161 5.46e-85 - - - G - - - Domain of unknown function (DUF386)
HLADNGJO_01162 2.45e-236 - - - G - - - Sugar (and other) transporter
HLADNGJO_01163 3.05e-81 - - - G - - - Domain of unknown function (DUF386)
HLADNGJO_01164 1.55e-65 - - - K - - - DeoR C terminal sensor domain
HLADNGJO_01165 6.81e-51 - - - - - - - -
HLADNGJO_01166 2.17e-228 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
HLADNGJO_01167 2.01e-79 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLADNGJO_01168 8.15e-280 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HLADNGJO_01169 7.79e-34 sgaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HLADNGJO_01170 3.64e-118 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
HLADNGJO_01171 9.79e-65 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
HLADNGJO_01172 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLADNGJO_01173 5.16e-48 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_01174 1.54e-141 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_01175 1.24e-160 rcfB - - K - - - Crp-like helix-turn-helix domain
HLADNGJO_01176 1.24e-305 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
HLADNGJO_01177 2.36e-168 larB - - S ko:K06898 - ko00000 AIR carboxylase
HLADNGJO_01178 1.52e-300 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HLADNGJO_01179 1.33e-166 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HLADNGJO_01180 1.14e-191 larE - - S ko:K06864 - ko00000 NAD synthase
HLADNGJO_01181 4.84e-233 hoxN - - U ko:K07241 - ko00000,ko02000 High-affinity nickel-transport protein
HLADNGJO_01182 5.96e-154 tnp1216 - - L ko:K07498 - ko00000 DDE domain
HLADNGJO_01183 3.1e-46 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLADNGJO_01184 5.46e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLADNGJO_01185 1.97e-174 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
HLADNGJO_01186 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLADNGJO_01187 2.72e-314 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
HLADNGJO_01188 3.45e-175 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HLADNGJO_01190 2.16e-98 uspA3 - - T - - - universal stress protein
HLADNGJO_01191 6.25e-78 - - - - - - - -
HLADNGJO_01192 1.25e-09 - - - - - - - -
HLADNGJO_01193 1.58e-202 - - - - - - - -
HLADNGJO_01194 2.22e-98 - - - K - - - Transcriptional regulator
HLADNGJO_01195 1.77e-238 ybcH - - D ko:K06889 - ko00000 Alpha beta
HLADNGJO_01196 1.1e-94 - - - O - - - OsmC-like protein
HLADNGJO_01197 9.62e-247 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
HLADNGJO_01198 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HLADNGJO_01199 8.87e-23 - - - - - - - -
HLADNGJO_01200 1.44e-147 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HLADNGJO_01201 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_01202 1.17e-130 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HLADNGJO_01203 3.41e-231 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HLADNGJO_01204 1.51e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HLADNGJO_01205 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HLADNGJO_01206 6.69e-47 copZ - - P - - - Heavy-metal-associated domain
HLADNGJO_01207 8.02e-130 dpsB - - P - - - Belongs to the Dps family
HLADNGJO_01208 7.69e-142 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
HLADNGJO_01209 1.3e-110 - - - - - - - -
HLADNGJO_01210 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLADNGJO_01211 1.35e-161 pgm3 - - G - - - phosphoglycerate mutase family
HLADNGJO_01212 5.62e-192 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HLADNGJO_01213 2.15e-299 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HLADNGJO_01214 3.77e-217 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HLADNGJO_01215 1.12e-212 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HLADNGJO_01216 8.27e-182 yceF - - P ko:K05794 - ko00000 membrane
HLADNGJO_01217 3.45e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HLADNGJO_01218 4.92e-288 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_01219 3.32e-211 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLADNGJO_01220 3.52e-311 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_01221 9.89e-207 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HLADNGJO_01222 1.98e-234 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HLADNGJO_01223 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HLADNGJO_01224 2.27e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HLADNGJO_01225 1.29e-298 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HLADNGJO_01226 2.17e-286 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HLADNGJO_01228 9.28e-171 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_01229 3.76e-193 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HLADNGJO_01230 4.65e-230 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HLADNGJO_01231 0.0 - - - S - - - ABC transporter, ATP-binding protein
HLADNGJO_01232 1.64e-262 yngD - - S ko:K07097 - ko00000 DHHA1 domain
HLADNGJO_01233 8.3e-141 yciB - - M - - - ErfK YbiS YcfS YnhG
HLADNGJO_01234 1.64e-108 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
HLADNGJO_01235 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLADNGJO_01236 1.32e-217 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
HLADNGJO_01237 8.41e-235 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
HLADNGJO_01238 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HLADNGJO_01239 2.41e-148 - - - S - - - HAD hydrolase, family IA, variant
HLADNGJO_01240 2.73e-227 - 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HLADNGJO_01241 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HLADNGJO_01242 1.15e-260 yhdG - - E ko:K03294 - ko00000 Amino Acid
HLADNGJO_01243 8.97e-95 - - - F - - - Nudix hydrolase
HLADNGJO_01244 9.61e-137 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HLADNGJO_01245 2.97e-109 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HLADNGJO_01246 4.69e-10 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HLADNGJO_01247 1.66e-215 - - - - - - - -
HLADNGJO_01248 1.38e-251 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HLADNGJO_01249 4.23e-122 - - - K - - - Transcriptional regulator (TetR family)
HLADNGJO_01250 2.88e-308 yhgE - - V ko:K01421 - ko00000 domain protein
HLADNGJO_01251 2.78e-172 - - - L - - - Transposase and inactivated derivatives, IS30 family
HLADNGJO_01252 4.87e-159 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLADNGJO_01253 6.54e-70 - - - - - - - -
HLADNGJO_01254 5.88e-10 - - - - - - - -
HLADNGJO_01256 1.3e-169 - 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 UDP-N-acetylglucosamine 2-epimerase
HLADNGJO_01257 1.23e-134 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLADNGJO_01258 4.47e-127 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_01259 1.83e-69 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_01260 0.0 - - - E - - - amino acid
HLADNGJO_01261 3.55e-173 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HLADNGJO_01262 3.75e-267 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HLADNGJO_01263 5.91e-297 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLADNGJO_01264 5.5e-155 pgm3 - - G - - - phosphoglycerate mutase
HLADNGJO_01265 2.5e-153 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HLADNGJO_01266 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HLADNGJO_01267 2.34e-205 - - - EG - - - EamA-like transporter family
HLADNGJO_01268 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLADNGJO_01269 2.9e-172 - - - IQ - - - dehydrogenase reductase
HLADNGJO_01270 2.05e-137 - - - K - - - acetyltransferase
HLADNGJO_01271 1.61e-223 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HLADNGJO_01272 3.62e-165 sptS - - T - - - Histidine kinase
HLADNGJO_01273 1.65e-101 dltr - - K - - - response regulator
HLADNGJO_01274 1.65e-146 - - - T - - - Region found in RelA / SpoT proteins
HLADNGJO_01275 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HLADNGJO_01276 0.0 - 1.7.2.5 - P ko:K04561 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Cytochrome C and Quinol oxidase polypeptide I
HLADNGJO_01277 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
HLADNGJO_01278 5.49e-11 - - - S - - - Domain of unknown function (DUF4767)
HLADNGJO_01279 5.32e-108 - - - - - - - -
HLADNGJO_01280 1.17e-135 - - - S - - - Domain of unknown function (DUF4767)
HLADNGJO_01281 6.7e-72 - - - K - - - Helix-turn-helix domain
HLADNGJO_01282 5.38e-222 - 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HLADNGJO_01283 1.1e-07 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
HLADNGJO_01284 3.9e-94 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
HLADNGJO_01285 2.52e-66 ybjQ - - S - - - Belongs to the UPF0145 family
HLADNGJO_01286 5.84e-48 - 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLADNGJO_01287 3.15e-86 - 2.2.1.7 - HI ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 1-deoxy-D-xylulose-5-phosphate synthase
HLADNGJO_01288 6.22e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_01289 7.29e-54 - - - L - - - Transposase, IS116 IS110 IS902 family
HLADNGJO_01290 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HLADNGJO_01291 1.21e-149 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_01292 2.99e-133 - - - T - - - Histidine kinase-like ATPases
HLADNGJO_01293 5.47e-125 XK27_10500 - - K - - - response regulator
HLADNGJO_01294 8.87e-287 - - - L - - - MULE transposase domain
HLADNGJO_01295 1.91e-150 - - - K - - - Bacterial regulatory proteins, tetR family
HLADNGJO_01296 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_01297 6.09e-72 - - - S - - - FMN_bind
HLADNGJO_01298 2.94e-217 - - - M ko:K02004 - ko00000,ko00002,ko02000 Membrane
HLADNGJO_01299 7.96e-30 XK27_06785 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HLADNGJO_01300 4.59e-133 - - - K - - - Transcriptional regulator
HLADNGJO_01301 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLADNGJO_01302 4.13e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLADNGJO_01303 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HLADNGJO_01304 2.74e-68 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HLADNGJO_01305 2.52e-200 yneP - - L ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HLADNGJO_01306 3.59e-10 - - - S - - - NADPH-dependent FMN reductase
HLADNGJO_01307 1.28e-107 - - - S - - - NADPH-dependent FMN reductase
HLADNGJO_01308 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
HLADNGJO_01309 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLADNGJO_01310 3.57e-59 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_01311 7.29e-290 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_01313 9.56e-196 - - - S ko:K07088 - ko00000 Membrane transport protein
HLADNGJO_01314 5.57e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HLADNGJO_01315 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
HLADNGJO_01316 1.2e-264 - - - EGP - - - Major Facilitator
HLADNGJO_01317 1.55e-274 ycsG - - P - - - Natural resistance-associated macrophage protein
HLADNGJO_01318 5.84e-172 - - - S ko:K07160 - ko00000 LamB/YcsF family
HLADNGJO_01319 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HLADNGJO_01320 2.33e-89 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLADNGJO_01321 3.48e-245 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HLADNGJO_01322 4.42e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HLADNGJO_01323 2.31e-95 - - - K - - - helix_turn_helix, mercury resistance
HLADNGJO_01324 4.35e-108 - - - S - - - Psort location Cytoplasmic, score
HLADNGJO_01325 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HLADNGJO_01326 1.03e-123 - - - K - - - Acetyltransferase (GNAT) family
HLADNGJO_01327 3.07e-135 - - - NU - - - mannosyl-glycoprotein
HLADNGJO_01328 5.59e-250 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HLADNGJO_01329 9.01e-33 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HLADNGJO_01330 4.27e-274 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HLADNGJO_01331 1.62e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLADNGJO_01332 8.11e-52 - - - S - - - Cytochrome B5
HLADNGJO_01335 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HLADNGJO_01336 2.79e-125 - - - K - - - transcriptional regulator
HLADNGJO_01337 2.72e-93 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HLADNGJO_01338 0.0 - - - L - - - Helicase C-terminal domain protein
HLADNGJO_01339 5.37e-72 - - - S - - - MazG-like family
HLADNGJO_01340 5.35e-139 - - - I - - - PAP2 superfamily
HLADNGJO_01341 2.12e-253 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HLADNGJO_01342 1.28e-126 - - - - - - - -
HLADNGJO_01343 9.93e-285 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HLADNGJO_01344 5.35e-217 - - - V - - - Beta-lactamase enzyme family
HLADNGJO_01345 0.0 potE - - E - - - Amino Acid
HLADNGJO_01347 2.74e-144 - - - - - - - -
HLADNGJO_01348 2.72e-212 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
HLADNGJO_01349 1.71e-211 - - - K - - - LysR substrate binding domain
HLADNGJO_01350 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HLADNGJO_01351 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HLADNGJO_01352 6.77e-249 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
HLADNGJO_01353 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLADNGJO_01354 1.87e-139 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLADNGJO_01355 2e-81 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_01356 2.22e-204 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_01357 1.22e-57 - - - I - - - alpha/beta hydrolase fold
HLADNGJO_01358 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase N-terminal domain
HLADNGJO_01359 0.0 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
HLADNGJO_01360 1.73e-97 - - - K - - - AraC-like ligand binding domain
HLADNGJO_01361 7.92e-170 - - - EGP - - - Major Facilitator Superfamily
HLADNGJO_01362 1.61e-214 - 3.2.1.37, 3.2.1.55 GH43,GH51 G ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HLADNGJO_01363 1.59e-185 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HLADNGJO_01364 1.86e-260 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
HLADNGJO_01365 3.88e-64 nlhH_1 - - I ko:K01066 - ko00000,ko01000 acetylesterase activity
HLADNGJO_01366 2.71e-198 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_01367 1.23e-27 - - - L - - - Helix-turn-helix domain
HLADNGJO_01368 4.5e-98 mleR - - K - - - LysR family
HLADNGJO_01369 5.92e-287 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HLADNGJO_01370 1.43e-233 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HLADNGJO_01371 2.48e-117 - - - S - - - NADPH-dependent FMN reductase
HLADNGJO_01372 1.26e-280 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLADNGJO_01373 5.27e-269 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HLADNGJO_01374 7.13e-288 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HLADNGJO_01375 9.16e-209 mleR2 - - K - - - LysR family transcriptional regulator
HLADNGJO_01376 0.0 - - - S - - - Putative threonine/serine exporter
HLADNGJO_01377 2.42e-155 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HLADNGJO_01378 1.92e-241 - - - I - - - Alpha beta
HLADNGJO_01379 7.04e-139 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HLADNGJO_01380 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLADNGJO_01382 4.08e-215 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HLADNGJO_01383 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
HLADNGJO_01384 3.85e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HLADNGJO_01385 1.7e-259 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
HLADNGJO_01386 2.74e-315 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLADNGJO_01387 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HLADNGJO_01388 1.35e-149 - - - S - - - Domain of unknown function (DUF4811)
HLADNGJO_01389 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HLADNGJO_01390 3.98e-96 - - - K - - - MerR HTH family regulatory protein
HLADNGJO_01391 1.4e-78 - - - - - - - -
HLADNGJO_01392 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLADNGJO_01393 9.28e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLADNGJO_01394 2.37e-28 elaA - - S ko:K02348 - ko00000 acyltransferase COG2153
HLADNGJO_01395 2.49e-110 - - - T - - - Belongs to the universal stress protein A family
HLADNGJO_01396 2e-143 - - - S - - - VIT family
HLADNGJO_01397 9.24e-151 - - - S - - - membrane
HLADNGJO_01398 2.07e-207 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HLADNGJO_01399 2.51e-158 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HLADNGJO_01400 1.26e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HLADNGJO_01401 1.36e-161 - - - S - - - Putative threonine/serine exporter
HLADNGJO_01402 3.33e-106 - - - S - - - Threonine/Serine exporter, ThrE
HLADNGJO_01403 3.13e-149 - - - I - - - phosphatase
HLADNGJO_01404 2.43e-199 - - - I - - - alpha/beta hydrolase fold
HLADNGJO_01406 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HLADNGJO_01407 4.69e-151 dgk2 - - F - - - deoxynucleoside kinase
HLADNGJO_01413 5.16e-15 fabG1 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLADNGJO_01414 1.16e-56 - - - IQ - - - reductase
HLADNGJO_01415 7.14e-191 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HLADNGJO_01416 3.92e-68 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HLADNGJO_01417 7.94e-92 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
HLADNGJO_01418 2.84e-72 rmeB - - K - - - transcriptional regulator, MerR family
HLADNGJO_01419 2.1e-148 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLADNGJO_01420 1.02e-95 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Hexapeptide repeat of succinyl-transferase
HLADNGJO_01421 6.07e-154 - - - J - - - 2'-5' RNA ligase superfamily
HLADNGJO_01422 1.69e-170 XK27_07210 - - S - - - B3 4 domain
HLADNGJO_01423 1.37e-247 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HLADNGJO_01424 6.36e-103 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HLADNGJO_01425 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLADNGJO_01426 8.51e-137 - - - K - - - Bacterial regulatory proteins, tetR family
HLADNGJO_01427 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLADNGJO_01428 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLADNGJO_01429 4.14e-173 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HLADNGJO_01430 3.02e-275 - - - - - - - -
HLADNGJO_01431 1.77e-40 pilD 3.4.23.43 - NOU ko:K02236,ko:K02506,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 aspartic-type endopeptidase activity
HLADNGJO_01432 3.58e-93 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLADNGJO_01433 4.15e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLADNGJO_01434 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLADNGJO_01435 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_01436 3.14e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HLADNGJO_01437 5.89e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLADNGJO_01438 1.56e-137 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HLADNGJO_01439 2.76e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLADNGJO_01440 3.32e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLADNGJO_01441 1.51e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLADNGJO_01442 2.63e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLADNGJO_01443 3.43e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLADNGJO_01444 2.78e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLADNGJO_01445 1.35e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HLADNGJO_01446 4.48e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLADNGJO_01447 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLADNGJO_01448 1.28e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLADNGJO_01449 1.75e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLADNGJO_01450 2.46e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLADNGJO_01451 7.64e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLADNGJO_01452 2.4e-120 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLADNGJO_01453 5.55e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLADNGJO_01454 3.59e-113 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLADNGJO_01455 6.96e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HLADNGJO_01456 3.5e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HLADNGJO_01457 5.51e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLADNGJO_01458 3.59e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLADNGJO_01459 1.69e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLADNGJO_01460 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HLADNGJO_01461 1.32e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLADNGJO_01462 8.02e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLADNGJO_01463 3.48e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLADNGJO_01464 1.02e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HLADNGJO_01465 2.49e-192 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLADNGJO_01466 2.06e-201 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLADNGJO_01467 2.37e-178 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLADNGJO_01468 4.68e-187 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLADNGJO_01469 5.57e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLADNGJO_01470 2.78e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HLADNGJO_01471 7.25e-264 - - - S - - - interspecies interaction between organisms
HLADNGJO_01472 4.28e-178 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HLADNGJO_01473 2.33e-142 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HLADNGJO_01474 9.17e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLADNGJO_01475 7.47e-280 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLADNGJO_01476 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HLADNGJO_01477 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLADNGJO_01478 1.94e-233 camS - - S - - - sex pheromone
HLADNGJO_01479 9.93e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLADNGJO_01480 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLADNGJO_01481 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLADNGJO_01482 8.8e-238 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HLADNGJO_01483 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLADNGJO_01484 1.67e-74 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HLADNGJO_01485 3.24e-62 - - - K - - - Psort location Cytoplasmic, score
HLADNGJO_01486 2.22e-101 - - - Q - - - Methyltransferase domain
HLADNGJO_01488 0.0 - - - L - - - Recombinase
HLADNGJO_01489 0.0 - - - L - - - Recombinase zinc beta ribbon domain
HLADNGJO_01490 2.15e-41 - - - - - - - -
HLADNGJO_01491 2.33e-172 - - - M - - - Glycosyl hydrolases family 25
HLADNGJO_01492 3.43e-82 - - - S - - - Bacteriophage holin family
HLADNGJO_01493 5.04e-79 - - - S - - - Phage head-tail joining protein
HLADNGJO_01494 5.76e-53 - - - S - - - Phage gp6-like head-tail connector protein
HLADNGJO_01495 1e-253 - - - S - - - Phage capsid family
HLADNGJO_01496 2.85e-141 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HLADNGJO_01497 3.67e-292 - - - S - - - Phage portal protein
HLADNGJO_01498 2.5e-197 - - - S - - - overlaps another CDS with the same product name
HLADNGJO_01499 2.4e-41 - - - S - - - Domain of unknown function (DUF5049)
HLADNGJO_01500 7.59e-101 - - - S - - - Psort location Cytoplasmic, score
HLADNGJO_01502 1.9e-291 - - - KL - - - DNA methylase
HLADNGJO_01503 6.35e-126 - - - - - - - -
HLADNGJO_01504 1.18e-291 - - - L - - - MULE transposase domain
HLADNGJO_01505 6.4e-97 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH nucleases
HLADNGJO_01506 1.06e-105 - - - - - - - -
HLADNGJO_01507 0.0 - - - L - - - SNF2 family N-terminal domain
HLADNGJO_01508 6.15e-62 - - - S - - - VRR_NUC
HLADNGJO_01509 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
HLADNGJO_01510 3.05e-91 - - - S - - - Psort location Cytoplasmic, score
HLADNGJO_01511 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase
HLADNGJO_01512 8.71e-125 - - - S - - - Protein of unknown function (DUF2815)
HLADNGJO_01513 5.77e-267 - - - L - - - Protein of unknown function (DUF2800)
HLADNGJO_01514 1.66e-58 - - - - - - - -
HLADNGJO_01515 1.8e-31 - - - - - - - -
HLADNGJO_01517 9.28e-292 - - - - - - - -
HLADNGJO_01518 0.0 - - - - - - - -
HLADNGJO_01519 1.63e-52 - - - K - - - Cro/C1-type HTH DNA-binding domain
HLADNGJO_01520 0.0 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
HLADNGJO_01521 0.0 res 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
HLADNGJO_01522 2.61e-298 - - - K - - - DNA binding
HLADNGJO_01523 0.0 - - - L - - - helicase activity
HLADNGJO_01525 1.36e-65 - - - K - - - TRANSCRIPTIONal
HLADNGJO_01526 1.59e-108 - - - K - - - Helix-turn-helix XRE-family like proteins
HLADNGJO_01527 3.32e-112 - - - K - - - Psort location CytoplasmicMembrane, score
HLADNGJO_01528 2.14e-147 - - - S ko:K07126 - ko00000 Sel1-like repeats.
HLADNGJO_01529 1.01e-83 - - - S - - - YjbR
HLADNGJO_01531 5.92e-157 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HLADNGJO_01532 1.37e-138 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLADNGJO_01533 9.21e-19 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
HLADNGJO_01534 1.23e-29 - - - D ko:K19158 - ko00000,ko01000,ko02048 mRNA cleavage
HLADNGJO_01535 1.06e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HLADNGJO_01536 7.77e-127 - - - L - - - Transposase and inactivated derivatives, IS30 family
HLADNGJO_01537 2.4e-60 - - - L - - - MULE transposase domain
HLADNGJO_01538 2.18e-28 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HLADNGJO_01539 2.06e-166 - - - M - - - domain protein
HLADNGJO_01540 2.38e-108 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_01541 2.1e-216 - - - L ko:K07497 - ko00000 Integrase core domain
HLADNGJO_01542 1.68e-61 - - - L ko:K07483 - ko00000 Transposase
HLADNGJO_01543 2.38e-75 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_01544 1.07e-247 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HLADNGJO_01546 2.29e-96 - 3.5.3.18 - E ko:K01482 - ko00000,ko01000,ko04147 Amidinotransferase
HLADNGJO_01547 5.51e-116 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HLADNGJO_01548 0.0 sufI - - Q - - - Multicopper oxidase
HLADNGJO_01549 1.28e-67 - - - K - - - 2 iron, 2 sulfur cluster binding
HLADNGJO_01550 5.95e-120 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HLADNGJO_01551 3.51e-154 - - - Q - - - Methyltransferase domain
HLADNGJO_01553 1.58e-132 - - - S - - - CAAX protease self-immunity
HLADNGJO_01554 1.52e-129 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLADNGJO_01555 6.99e-101 - - - EGP - - - Major Facilitator Superfamily
HLADNGJO_01556 7.78e-61 - - - EGP - - - Major Facilitator Superfamily
HLADNGJO_01557 2.39e-131 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLADNGJO_01558 9.31e-275 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HLADNGJO_01559 1.05e-134 - - - - - - - -
HLADNGJO_01560 4.16e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HLADNGJO_01561 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HLADNGJO_01562 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_01563 2.89e-44 yneR - - S - - - Belongs to the HesB IscA family
HLADNGJO_01564 2.58e-180 - - - S - - - NADPH-dependent FMN reductase
HLADNGJO_01565 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HLADNGJO_01566 7.48e-205 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HLADNGJO_01567 1.8e-134 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HLADNGJO_01568 2.11e-82 - - - S - - - Domain of unknown function (DUF4828)
HLADNGJO_01569 3.33e-242 mocA - - S - - - Oxidoreductase
HLADNGJO_01570 1.42e-305 yfmL - - L - - - DEAD DEAH box helicase
HLADNGJO_01573 1.38e-98 gtcA - - S - - - Teichoic acid glycosylation protein
HLADNGJO_01574 3.91e-100 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HLADNGJO_01575 1.17e-214 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HLADNGJO_01576 2.96e-100 XK27_08315 - - M - - - Sulfatase
HLADNGJO_01577 0.0 XK27_08315 - - M - - - Sulfatase
HLADNGJO_01578 5.86e-192 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HLADNGJO_01579 4.37e-43 - - - S - - - Protein of unknown function (DUF2922)
HLADNGJO_01581 1.18e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HLADNGJO_01582 1.73e-152 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HLADNGJO_01583 1.71e-191 cps1D - - M - - - Domain of unknown function (DUF4422)
HLADNGJO_01584 5.64e-41 - - - M - - - biosynthesis protein
HLADNGJO_01585 7.17e-84 - - - M - - - Domain of unknown function (DUF4422)
HLADNGJO_01586 6.46e-84 - - - - - - - -
HLADNGJO_01587 6.13e-107 - - - M - - - transferase activity, transferring glycosyl groups
HLADNGJO_01588 1.11e-94 - - - M - - - Core-2/I-Branching enzyme
HLADNGJO_01589 3.14e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HLADNGJO_01590 1.31e-275 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HLADNGJO_01591 9.46e-87 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
HLADNGJO_01592 1.28e-78 - - - S - - - enterobacterial common antigen metabolic process
HLADNGJO_01593 6.95e-60 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HLADNGJO_01594 2.95e-210 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLADNGJO_01595 3.74e-47 - - - M - - - KxYKxGKxW signal domain protein
HLADNGJO_01596 2.85e-68 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HLADNGJO_01597 8.03e-10 - - - - - - - -
HLADNGJO_01598 6.59e-204 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HLADNGJO_01599 1.99e-217 yueF - - S - - - AI-2E family transporter
HLADNGJO_01600 2.97e-34 - - - S - - - Psort location CytoplasmicMembrane, score
HLADNGJO_01601 6.32e-211 ykoT - - M - - - Glycosyl transferase family 2
HLADNGJO_01602 1.14e-239 - - - S - - - Psort location CytoplasmicMembrane, score
HLADNGJO_01603 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HLADNGJO_01604 2.13e-93 - - - S - - - Bacterial membrane protein, YfhO
HLADNGJO_01605 1.4e-26 - - - S - - - Glycosyltransferase like family 2
HLADNGJO_01606 2.03e-130 - - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
HLADNGJO_01607 1.78e-214 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLADNGJO_01608 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
HLADNGJO_01609 1.8e-217 - - - L ko:K07497 - ko00000 Integrase core domain
HLADNGJO_01610 5.95e-84 - - - K - - - Transcriptional regulator, GntR family
HLADNGJO_01611 1.64e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_01614 6.53e-313 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HLADNGJO_01615 2.57e-207 - - - EG - - - EamA-like transporter family
HLADNGJO_01616 1.22e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLADNGJO_01617 1.91e-181 - - - G - - - MucBP domain
HLADNGJO_01618 6.63e-125 - - - S - - - Pfam:DUF3816
HLADNGJO_01619 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLADNGJO_01620 4.98e-142 pncA - - Q - - - Isochorismatase family
HLADNGJO_01621 5.03e-166 - - - F - - - NUDIX domain
HLADNGJO_01622 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HLADNGJO_01623 2.41e-07 - - - - - - - -
HLADNGJO_01624 2.14e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HLADNGJO_01625 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLADNGJO_01626 3.79e-292 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HLADNGJO_01627 3.81e-255 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HLADNGJO_01628 5.64e-231 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLADNGJO_01629 2.81e-53 - - - S - - - Protein of unknown function (DUF1797)
HLADNGJO_01632 8.34e-101 - - - - - - - -
HLADNGJO_01643 3.21e-05 - - - K - - - Transcriptional regulator
HLADNGJO_01644 9.58e-19 ebrB - - U ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HLADNGJO_01645 3.37e-183 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HLADNGJO_01646 1.11e-145 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HLADNGJO_01647 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HLADNGJO_01648 2.99e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLADNGJO_01649 5.71e-204 - - - O - - - Uncharacterized protein family (UPF0051)
HLADNGJO_01650 3.07e-300 - - - F ko:K03458 - ko00000 Permease
HLADNGJO_01651 1.31e-250 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
HLADNGJO_01652 4.25e-90 - - - M - - - LysM domain protein
HLADNGJO_01653 3.6e-112 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
HLADNGJO_01654 2.79e-102 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HLADNGJO_01655 1.44e-157 - - - K - - - Transcriptional regulator, TetR family
HLADNGJO_01658 4.14e-300 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_01659 3.32e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_01661 3.91e-31 - - - - - - - -
HLADNGJO_01662 1.37e-315 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HLADNGJO_01663 3.59e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HLADNGJO_01664 0.0 - - - EGP - - - Major Facilitator
HLADNGJO_01665 3.16e-125 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HLADNGJO_01666 4.58e-64 - - - - - - - -
HLADNGJO_01667 3.78e-271 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLADNGJO_01668 1.87e-180 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLADNGJO_01669 8.48e-284 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLADNGJO_01670 1.39e-161 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HLADNGJO_01671 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HLADNGJO_01672 9.88e-57 - - - - - - - -
HLADNGJO_01673 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HLADNGJO_01674 4.71e-81 - - - S - - - Domain of unknown function DUF302
HLADNGJO_01675 3.79e-195 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLADNGJO_01676 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HLADNGJO_01677 8.2e-113 - - - T - - - Belongs to the universal stress protein A family
HLADNGJO_01678 0.0 - - - S - - - Putative peptidoglycan binding domain
HLADNGJO_01679 2.3e-240 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLADNGJO_01680 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
HLADNGJO_01681 1.21e-143 - - - - - - - -
HLADNGJO_01682 6.39e-235 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HLADNGJO_01683 4.99e-153 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLADNGJO_01684 9.96e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLADNGJO_01685 6.44e-122 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HLADNGJO_01686 9.27e-133 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HLADNGJO_01687 5.82e-309 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HLADNGJO_01688 5.55e-137 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HLADNGJO_01689 7.33e-258 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HLADNGJO_01691 4.86e-53 - - - - - - - -
HLADNGJO_01693 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HLADNGJO_01694 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HLADNGJO_01695 3.95e-73 yheA - - S - - - Belongs to the UPF0342 family
HLADNGJO_01696 1.5e-229 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HLADNGJO_01697 3.63e-195 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLADNGJO_01699 2.49e-100 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HLADNGJO_01700 3.68e-171 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_01701 1.55e-274 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HLADNGJO_01702 9.51e-161 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLADNGJO_01703 6.83e-76 - - - S - - - Small secreted protein
HLADNGJO_01704 1.53e-72 ytpP - - CO - - - Thioredoxin
HLADNGJO_01705 1.11e-152 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLADNGJO_01706 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HLADNGJO_01707 1.24e-146 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HLADNGJO_01708 5.44e-177 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
HLADNGJO_01709 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLADNGJO_01710 7.57e-208 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLADNGJO_01711 4.15e-137 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLADNGJO_01712 3.44e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLADNGJO_01713 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HLADNGJO_01714 6.27e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HLADNGJO_01715 6.95e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLADNGJO_01716 5.22e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HLADNGJO_01717 4.67e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLADNGJO_01718 2.58e-24 - - - S - - - Protein of unknown function (DUF1275)
HLADNGJO_01719 7.57e-33 - - - S - - - Protein of unknown function (DUF1275)
HLADNGJO_01720 6.88e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HLADNGJO_01721 6.57e-275 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HLADNGJO_01722 1.38e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HLADNGJO_01723 1.62e-120 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLADNGJO_01724 5.53e-145 yqeK - - H - - - Hydrolase, HD family
HLADNGJO_01725 1.14e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLADNGJO_01726 7.76e-182 yqeM - - Q - - - Methyltransferase
HLADNGJO_01727 2.38e-273 ylbM - - S - - - Belongs to the UPF0348 family
HLADNGJO_01728 2.79e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HLADNGJO_01729 7.89e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HLADNGJO_01730 1.38e-155 csrR - - K - - - response regulator
HLADNGJO_01731 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLADNGJO_01732 1.55e-297 - - - V - - - MatE
HLADNGJO_01733 4.54e-91 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLADNGJO_01734 5.83e-199 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLADNGJO_01735 8.13e-62 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HLADNGJO_01736 4.52e-181 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLADNGJO_01737 4.08e-117 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HLADNGJO_01738 1.44e-78 yodB - - K - - - Transcriptional regulator, HxlR family
HLADNGJO_01739 4.45e-253 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLADNGJO_01740 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLADNGJO_01741 5.91e-151 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HLADNGJO_01742 1.81e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLADNGJO_01743 0.0 - - - S - - - membrane
HLADNGJO_01744 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HLADNGJO_01745 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HLADNGJO_01746 3.66e-127 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLADNGJO_01747 7.12e-150 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HLADNGJO_01748 1.14e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HLADNGJO_01749 1.83e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HLADNGJO_01750 5.91e-93 yqhL - - P - - - Rhodanese-like protein
HLADNGJO_01751 3.51e-33 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HLADNGJO_01752 1.04e-219 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLADNGJO_01753 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HLADNGJO_01754 4.76e-19 - - - - - - - -
HLADNGJO_01755 1.1e-200 - - - - - - - -
HLADNGJO_01756 2.34e-226 - - - - - - - -
HLADNGJO_01757 3.15e-120 - - - S - - - Protein conserved in bacteria
HLADNGJO_01759 1.29e-148 - - - K - - - Transcriptional regulator
HLADNGJO_01760 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HLADNGJO_01761 1.2e-70 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HLADNGJO_01762 8.74e-62 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HLADNGJO_01763 4.18e-263 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HLADNGJO_01764 2.1e-94 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HLADNGJO_01765 9.82e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLADNGJO_01766 1.16e-205 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLADNGJO_01767 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLADNGJO_01768 2.32e-25 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLADNGJO_01769 2.41e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HLADNGJO_01770 1.14e-189 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HLADNGJO_01771 9.93e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HLADNGJO_01772 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HLADNGJO_01774 1.03e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HLADNGJO_01775 1.9e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLADNGJO_01776 2.38e-274 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLADNGJO_01777 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLADNGJO_01778 5.61e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLADNGJO_01779 5.57e-316 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLADNGJO_01780 1.68e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HLADNGJO_01781 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HLADNGJO_01782 9.22e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLADNGJO_01783 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HLADNGJO_01784 3.05e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HLADNGJO_01785 5.82e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HLADNGJO_01786 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
HLADNGJO_01787 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HLADNGJO_01788 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLADNGJO_01789 8.95e-215 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLADNGJO_01790 1.65e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLADNGJO_01791 3.28e-165 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLADNGJO_01792 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HLADNGJO_01793 1.37e-294 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLADNGJO_01794 1.72e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLADNGJO_01795 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_01796 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLADNGJO_01798 5.3e-48 - - - - - - - -
HLADNGJO_01799 1.41e-40 - - - - - - - -
HLADNGJO_01800 7.18e-170 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
HLADNGJO_01801 5.7e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HLADNGJO_01802 7.93e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HLADNGJO_01803 1.74e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HLADNGJO_01804 8.24e-19 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLADNGJO_01805 4.29e-138 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLADNGJO_01806 2.78e-158 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HLADNGJO_01807 4.94e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HLADNGJO_01808 3.08e-52 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HLADNGJO_01809 2.4e-99 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLADNGJO_01810 2.22e-182 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HLADNGJO_01811 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HLADNGJO_01812 6.59e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLADNGJO_01813 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 CRISPR-associated helicase cas3
HLADNGJO_01814 2.2e-176 casA - - L ko:K19123 - ko00000,ko02048 the current gene model (or a revised gene model) may contain a frame shift
HLADNGJO_01815 1.59e-51 - - - S ko:K19046 - ko00000,ko02048 CRISPR-associated protein Cse2 (CRISPR_cse2)
HLADNGJO_01816 1.56e-163 casC - - L ko:K19124 - ko00000,ko02048 CT1975-like protein
HLADNGJO_01817 6.61e-81 casD - - S ko:K19125 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
HLADNGJO_01818 9.63e-90 casE - - S ko:K19126 - ko00000,ko02048 CRISPR_assoc
HLADNGJO_01819 2.53e-159 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLADNGJO_01820 2.24e-97 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas2CT1978)
HLADNGJO_01821 7.57e-195 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_01822 1.56e-73 ycsI - - S - - - Protein of unknown function (DUF1445)
HLADNGJO_01823 1.62e-230 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HLADNGJO_01824 1.55e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLADNGJO_01825 5.1e-265 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HLADNGJO_01826 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HLADNGJO_01827 9.19e-213 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLADNGJO_01828 5.29e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HLADNGJO_01829 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HLADNGJO_01830 9.53e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLADNGJO_01831 2.85e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HLADNGJO_01832 3.39e-120 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLADNGJO_01833 5.29e-263 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLADNGJO_01834 4.08e-271 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HLADNGJO_01835 1.29e-231 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HLADNGJO_01836 3.08e-214 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HLADNGJO_01837 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HLADNGJO_01838 6.66e-115 ypmB - - S - - - Protein conserved in bacteria
HLADNGJO_01839 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HLADNGJO_01840 4.14e-173 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HLADNGJO_01841 4.45e-189 ypuA - - S - - - Protein of unknown function (DUF1002)
HLADNGJO_01842 2.25e-241 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HLADNGJO_01843 6.64e-205 - - - EG - - - EamA-like transporter family
HLADNGJO_01844 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HLADNGJO_01845 1.4e-151 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLADNGJO_01846 1.26e-143 ypsA - - S - - - Belongs to the UPF0398 family
HLADNGJO_01847 2.08e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLADNGJO_01848 0.0 fusA1 - - J - - - elongation factor G
HLADNGJO_01849 1.07e-271 - - - S ko:K06915 - ko00000 AAA-like domain
HLADNGJO_01850 1.65e-106 - - - F - - - Hydrolase, NUDIX family
HLADNGJO_01851 3.68e-278 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HLADNGJO_01852 1.23e-206 arcT - - E - - - Dipeptidase
HLADNGJO_01853 6.42e-256 arcD - - S - - - C4-dicarboxylate anaerobic carrier
HLADNGJO_01854 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HLADNGJO_01855 1.15e-08 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_01856 2.9e-62 - - - L ko:K07483 - ko00000 Transposase
HLADNGJO_01857 5.07e-113 - - - L ko:K07497 - ko00000 Integrase core domain
HLADNGJO_01858 1.08e-267 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_01859 1.43e-153 yckA - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLADNGJO_01860 8.4e-200 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HLADNGJO_01861 1.36e-139 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HLADNGJO_01862 3.77e-93 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HLADNGJO_01863 1e-91 esbA - - S - - - Family of unknown function (DUF5322)
HLADNGJO_01864 1.27e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLADNGJO_01865 3e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HLADNGJO_01866 1.2e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HLADNGJO_01867 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HLADNGJO_01868 3.59e-154 - 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HLADNGJO_01869 3.5e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HLADNGJO_01870 7.67e-30 - - - S - - - Enoyl-(Acyl carrier protein) reductase
HLADNGJO_01871 5.86e-276 - - - L - - - Transposase and inactivated derivatives, IS30 family
HLADNGJO_01872 3.89e-75 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HLADNGJO_01873 2.51e-237 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
HLADNGJO_01874 2.94e-97 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLADNGJO_01875 5.59e-290 - - - L - - - MULE transposase domain
HLADNGJO_01876 1.29e-137 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_01877 0.0 FbpA - - K - - - Fibronectin-binding protein
HLADNGJO_01878 4.02e-205 - - - S - - - EDD domain protein, DegV family
HLADNGJO_01879 1.14e-128 - - - - - - - -
HLADNGJO_01880 1.55e-170 yaaA - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HLADNGJO_01881 1.76e-153 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HLADNGJO_01882 1.24e-146 ylbE - - GM - - - NAD(P)H-binding
HLADNGJO_01883 5.71e-126 - - - K - - - Acetyltransferase (GNAT) domain
HLADNGJO_01884 9.87e-203 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLADNGJO_01885 1.45e-297 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HLADNGJO_01886 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HLADNGJO_01887 6.93e-158 azlC - - E - - - azaleucine resistance protein AzlC
HLADNGJO_01888 7.76e-72 azlD - - E - - - Branched-chain amino acid transport
HLADNGJO_01889 4.9e-232 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HLADNGJO_01890 7.41e-229 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HLADNGJO_01891 4.26e-276 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLADNGJO_01892 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HLADNGJO_01893 2.03e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HLADNGJO_01894 7.39e-276 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HLADNGJO_01895 8.37e-43 rlrB - - K - - - LysR substrate binding domain protein
HLADNGJO_01896 7.1e-59 rlrB - - K - - - LysR substrate binding domain protein
HLADNGJO_01897 1.04e-270 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
HLADNGJO_01898 0.0 yhdP - - S - - - Transporter associated domain
HLADNGJO_01899 1.8e-271 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HLADNGJO_01900 7.61e-203 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
HLADNGJO_01901 1.53e-214 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HLADNGJO_01902 3.52e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLADNGJO_01903 6.43e-17 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLADNGJO_01904 1.08e-258 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLADNGJO_01905 2.25e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLADNGJO_01906 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HLADNGJO_01907 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HLADNGJO_01908 4.64e-36 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HLADNGJO_01909 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLADNGJO_01911 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HLADNGJO_01912 1.47e-66 - - - - - - - -
HLADNGJO_01913 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HLADNGJO_01915 7.61e-299 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HLADNGJO_01916 1.91e-199 - - - S - - - Alpha beta hydrolase
HLADNGJO_01917 1.3e-203 - - - GM - - - NAD(P)H-binding
HLADNGJO_01918 1.29e-195 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
HLADNGJO_01921 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HLADNGJO_01923 2.03e-272 - - - G - - - Major Facilitator Superfamily
HLADNGJO_01924 7.56e-15 aroH 5.4.99.5 - E ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
HLADNGJO_01925 7.65e-272 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HLADNGJO_01926 1.34e-132 - - - - - - - -
HLADNGJO_01927 1.58e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HLADNGJO_01928 2.37e-250 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HLADNGJO_01929 2.61e-117 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HLADNGJO_01930 9.06e-279 aspB3 - - E - - - DegT/DnrJ/EryC1/StrS aminotransferase family
HLADNGJO_01931 2.41e-235 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLADNGJO_01932 3.65e-226 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HLADNGJO_01933 6.35e-201 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HLADNGJO_01934 1.25e-31 - - - S - - - Virus attachment protein p12 family
HLADNGJO_01935 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HLADNGJO_01936 8.17e-45 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HLADNGJO_01937 2.69e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HLADNGJO_01938 8.98e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HLADNGJO_01939 2.6e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLADNGJO_01940 2.5e-109 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HLADNGJO_01941 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HLADNGJO_01942 3.05e-238 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HLADNGJO_01943 6.79e-183 - - - EG - - - EamA-like transporter family
HLADNGJO_01944 0.0 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HLADNGJO_01945 1.04e-26 - - - S - - - Domain of unknown function (DUF1858)
HLADNGJO_01946 3.62e-72 yitW - - S - - - Iron-sulfur cluster assembly protein
HLADNGJO_01947 1.55e-292 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HLADNGJO_01948 1.23e-181 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HLADNGJO_01949 5.1e-219 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLADNGJO_01950 4.07e-76 - - - S - - - Flavodoxin
HLADNGJO_01951 7.91e-95 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
HLADNGJO_01952 2.34e-47 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
HLADNGJO_01953 4.09e-250 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HLADNGJO_01954 3.15e-276 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Major Facilitator Superfamily
HLADNGJO_01955 2.36e-77 - - - S - - - Iron-sulfur cluster assembly protein
HLADNGJO_01956 1.65e-210 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HLADNGJO_01957 4.84e-170 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLADNGJO_01959 3.49e-217 - - - H - - - geranyltranstransferase activity
HLADNGJO_01960 2.07e-236 - - - - - - - -
HLADNGJO_01961 1.99e-53 - - - - - - - -
HLADNGJO_01962 1.83e-150 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HLADNGJO_01963 9.81e-241 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
HLADNGJO_01964 8.62e-102 nreA - - T ko:K10851 ko02020,map02020 ko00000,ko00001 GAF domain
HLADNGJO_01965 6.94e-54 - - - - - - - -
HLADNGJO_01966 7.14e-128 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HLADNGJO_01967 5.5e-108 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HLADNGJO_01968 8.99e-295 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
HLADNGJO_01969 1.79e-111 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HLADNGJO_01970 6.23e-244 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HLADNGJO_01971 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLADNGJO_01972 0.0 - 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HLADNGJO_01973 2.15e-132 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
HLADNGJO_01974 2.14e-164 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
HLADNGJO_01975 3.71e-236 - - - - - - - -
HLADNGJO_01976 1.01e-99 - - - - - - - -
HLADNGJO_01977 1.52e-82 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HLADNGJO_01978 2.77e-50 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HLADNGJO_01980 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HLADNGJO_01981 6.9e-124 - - - V - - - VanZ like family
HLADNGJO_01982 2.95e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HLADNGJO_01983 1.59e-80 - - - - - - - -
HLADNGJO_01984 8.05e-233 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
HLADNGJO_01985 2.34e-301 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HLADNGJO_01986 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HLADNGJO_01987 4.77e-219 - - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
HLADNGJO_01988 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_01990 6.03e-61 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HLADNGJO_01992 2.95e-106 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HLADNGJO_01993 3.92e-55 - - - - - - - -
HLADNGJO_01994 2.99e-218 - - - GK - - - ROK family
HLADNGJO_01995 1.23e-165 - - - C - - - Oxidoreductase NAD-binding domain
HLADNGJO_01996 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HLADNGJO_01997 6.33e-133 - - - K - - - Acetyltransferase (GNAT) family
HLADNGJO_01998 2.51e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLADNGJO_01999 1.73e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLADNGJO_02000 2.58e-71 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLADNGJO_02003 1.55e-66 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_02004 2.38e-301 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HLADNGJO_02005 4.94e-91 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HLADNGJO_02006 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLADNGJO_02007 9.81e-94 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HLADNGJO_02008 1.45e-129 - - - K - - - DNA-templated transcription, initiation
HLADNGJO_02010 0.0 - - - L - - - Type III restriction enzyme, res subunit
HLADNGJO_02011 4.51e-71 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
HLADNGJO_02013 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HLADNGJO_02014 6.4e-149 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_02015 7.72e-57 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HLADNGJO_02016 6.4e-95 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HLADNGJO_02017 1.11e-45 rmeB - - K - - - transcriptional regulator, MerR family
HLADNGJO_02018 3.24e-60 yrfB - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
HLADNGJO_02019 1.36e-144 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HLADNGJO_02020 3.81e-74 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphotyrosine protein phosphatase
HLADNGJO_02022 4.83e-277 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HLADNGJO_02023 0.0 guaD 3.5.4.3 - F ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
HLADNGJO_02024 5.19e-48 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HLADNGJO_02025 1.59e-130 - - - E - - - Zinc-binding dehydrogenase
HLADNGJO_02026 1.32e-39 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
HLADNGJO_02027 4.93e-287 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HLADNGJO_02028 1.35e-197 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HLADNGJO_02029 8.93e-185 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HLADNGJO_02031 1.81e-277 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HLADNGJO_02033 8.9e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HLADNGJO_02034 5.05e-128 - - - K - - - Virulence activator alpha C-term
HLADNGJO_02035 3.37e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HLADNGJO_02036 6.12e-33 - - - S - - - SNARE associated Golgi protein
HLADNGJO_02037 6.02e-17 - - - S - - - SNARE associated Golgi protein
HLADNGJO_02038 2.62e-302 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HLADNGJO_02039 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLADNGJO_02041 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HLADNGJO_02043 2.5e-236 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HLADNGJO_02044 4.96e-84 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HLADNGJO_02045 3.89e-209 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HLADNGJO_02046 1.72e-212 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HLADNGJO_02047 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLADNGJO_02048 3.06e-206 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HLADNGJO_02050 3.77e-289 - - - - - - - -
HLADNGJO_02051 1.67e-249 flp - - V - - - Beta-lactamase
HLADNGJO_02052 8.23e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
HLADNGJO_02053 2.08e-159 - - - S ko:K07090 - ko00000 membrane transporter protein
HLADNGJO_02054 1.1e-237 XK27_12525 - - S - - - AI-2E family transporter
HLADNGJO_02055 2.2e-272 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HLADNGJO_02056 8.16e-206 rssA - - S - - - Phospholipase, patatin family
HLADNGJO_02057 4.52e-213 - - - K - - - LysR substrate binding domain
HLADNGJO_02058 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HLADNGJO_02059 2.52e-108 - - - S - - - Domain of unknown function (DUF4352)
HLADNGJO_02060 7.06e-145 yicL - - EG - - - EamA-like transporter family
HLADNGJO_02061 2.65e-84 - - - - - - - -
HLADNGJO_02064 3.05e-46 - - - - - - - -
HLADNGJO_02065 3.96e-89 - - - S - - - pyridoxamine 5-phosphate
HLADNGJO_02066 4.75e-228 - - - K - - - WYL domain
HLADNGJO_02067 6.62e-312 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HLADNGJO_02068 1.65e-53 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HLADNGJO_02069 2.86e-215 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HLADNGJO_02070 7.93e-270 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HLADNGJO_02071 3.19e-221 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
HLADNGJO_02072 4.32e-278 - - - G - - - Transporter, major facilitator family protein
HLADNGJO_02073 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HLADNGJO_02074 1.2e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HLADNGJO_02075 1.34e-74 yuxO - - Q - - - Thioesterase superfamily
HLADNGJO_02076 2.71e-43 - - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HLADNGJO_02077 2.72e-27 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLADNGJO_02078 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HLADNGJO_02079 1.33e-205 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HLADNGJO_02080 8.63e-09 - - - C - - - Domain of unknown function (DUF4145)
HLADNGJO_02081 3.37e-291 - - - L - - - MULE transposase domain
HLADNGJO_02082 7.18e-156 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HLADNGJO_02083 4.64e-184 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HLADNGJO_02084 3.38e-122 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HLADNGJO_02085 7.73e-13 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLADNGJO_02086 9.68e-67 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HLADNGJO_02087 5.38e-138 - - - GK - - - ROK family
HLADNGJO_02088 7.78e-235 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HLADNGJO_02089 6.08e-17 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HLADNGJO_02090 1.91e-21 ISPlu1B - - L ko:K07482 - ko00000 IS30 family
HLADNGJO_02091 5.38e-272 - - - L - - - Transposase and inactivated derivatives, IS30 family
HLADNGJO_02092 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
HLADNGJO_02093 1.72e-36 XK27_02560 - - S - - - Pfam:DUF59
HLADNGJO_02094 2.32e-166 yocS - - S ko:K03453 - ko00000 Transporter
HLADNGJO_02095 9.7e-309 - - - EGP ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
HLADNGJO_02096 3.51e-250 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HLADNGJO_02097 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLADNGJO_02098 2.56e-141 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLADNGJO_02099 2.14e-187 XK27_00020 - - J - - - Telomere recombination
HLADNGJO_02100 3.39e-06 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HLADNGJO_02101 2.23e-44 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HLADNGJO_02102 0.000602 - - - G - - - COG2513 PEP phosphonomutase and related enzymes
HLADNGJO_02103 3.07e-20 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
HLADNGJO_02104 1.18e-105 - - - G ko:K08368,ko:K08369 - ko00000,ko02000 Major Facilitator
HLADNGJO_02105 6.45e-06 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HLADNGJO_02106 2.3e-73 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLADNGJO_02107 1.66e-38 - - - IQ - - - oxidoreductase activity
HLADNGJO_02108 4e-67 - - - C - - - Flavodoxin
HLADNGJO_02109 4.03e-104 yicL - - EG - - - EamA-like transporter family
HLADNGJO_02110 3.44e-64 yicL - - EG - - - EamA-like transporter family
HLADNGJO_02111 3.77e-139 - - - L - - - Integrase
HLADNGJO_02112 2.43e-28 - - - K - - - transcriptional regulator
HLADNGJO_02113 9.75e-20 - - - K - - - transcriptional regulator
HLADNGJO_02114 2.8e-119 - - - GM - - - NmrA-like family
HLADNGJO_02115 1.9e-32 - - - C - - - Flavodoxin
HLADNGJO_02116 1.08e-94 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HLADNGJO_02117 5.23e-97 - - - O ko:K07397 - ko00000 OsmC-like protein
HLADNGJO_02118 7.28e-101 ywnA - - K - - - Transcriptional regulator
HLADNGJO_02119 2.33e-208 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
HLADNGJO_02120 1.8e-138 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HLADNGJO_02121 3.14e-179 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_02122 7.95e-132 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
HLADNGJO_02123 2.15e-234 - - - C - - - Zinc-binding dehydrogenase
HLADNGJO_02124 2.03e-250 bdhA 1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4 - C ko:K00004,ko:K00008,ko:K00098 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HLADNGJO_02125 1.41e-109 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HLADNGJO_02126 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_02127 3.07e-159 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HLADNGJO_02128 5.89e-231 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLADNGJO_02129 1.77e-260 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
HLADNGJO_02130 2.81e-121 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HLADNGJO_02131 2.42e-301 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
HLADNGJO_02132 1.57e-194 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HLADNGJO_02133 1.85e-105 - - - S - - - ECF-type riboflavin transporter, S component
HLADNGJO_02134 4.95e-113 yvgN - - C - - - Aldo keto reductase
HLADNGJO_02135 8.28e-37 yvgN - - C - - - Aldo keto reductase
HLADNGJO_02136 6.16e-208 - - - S - - - DUF218 domain
HLADNGJO_02138 3.31e-125 - 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HLADNGJO_02139 2.21e-210 - - - I - - - alpha/beta hydrolase fold
HLADNGJO_02140 4e-92 - - - S - - - Phage minor capsid protein 2
HLADNGJO_02141 2.64e-45 - - - S - - - Phage minor capsid protein 2
HLADNGJO_02144 1.81e-274 - - - E - - - Aminotransferase
HLADNGJO_02145 3.01e-110 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
HLADNGJO_02146 2.02e-64 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
HLADNGJO_02147 3.18e-315 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HLADNGJO_02148 1.32e-125 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
HLADNGJO_02150 4.91e-107 - - - S - - - Fic/DOC family
HLADNGJO_02151 1.22e-118 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HLADNGJO_02152 3.14e-140 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HLADNGJO_02153 5.43e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HLADNGJO_02154 0.0 - - - E ko:K03758 - ko00000,ko02000 Amino acid permease
HLADNGJO_02155 1.02e-153 - - - M - - - racemase activity, acting on amino acids and derivatives
HLADNGJO_02156 1.05e-195 - - - C - - - NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
HLADNGJO_02157 8.82e-11 eriC - - P ko:K03281 - ko00000 chloride
HLADNGJO_02158 1.01e-10 eriC - - P ko:K03281 - ko00000 chloride
HLADNGJO_02159 1.53e-47 eriC - - P ko:K03281 - ko00000 chloride
HLADNGJO_02160 1.38e-06 eriC - - P ko:K03281 - ko00000 chloride
HLADNGJO_02161 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_02162 1e-22 ycnB - - U - - - Belongs to the major facilitator superfamily
HLADNGJO_02163 4.3e-312 yhjX - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HLADNGJO_02164 8.95e-151 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HLADNGJO_02165 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HLADNGJO_02167 0.0 - - - EP - - - Psort location Cytoplasmic, score
HLADNGJO_02168 3.75e-307 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
HLADNGJO_02169 2.4e-312 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HLADNGJO_02170 4.02e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HLADNGJO_02171 3.6e-122 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HLADNGJO_02172 4.65e-100 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HLADNGJO_02173 7.86e-92 - - - S - - - Belongs to the HesB IscA family
HLADNGJO_02174 4.6e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HLADNGJO_02175 2.53e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HLADNGJO_02176 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLADNGJO_02177 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLADNGJO_02178 2.14e-133 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLADNGJO_02179 9.3e-220 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HLADNGJO_02180 3.04e-196 - - - D - - - DNA integration
HLADNGJO_02181 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLADNGJO_02182 2.55e-212 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HLADNGJO_02183 8.69e-182 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLADNGJO_02184 1.46e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLADNGJO_02185 2.1e-49 yozE - - S - - - Belongs to the UPF0346 family
HLADNGJO_02186 2.85e-135 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HLADNGJO_02187 2.46e-217 - - - E - - - lipolytic protein G-D-S-L family
HLADNGJO_02188 1.2e-146 cat 2.3.1.79 - S ko:K00661,ko:K18234 - ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
HLADNGJO_02189 4.15e-278 - 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase
HLADNGJO_02190 9.45e-198 WQ51_01275 - - S - - - EDD domain protein, DegV family
HLADNGJO_02191 8.06e-141 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HLADNGJO_02192 4.4e-122 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLADNGJO_02193 3.08e-243 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLADNGJO_02194 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HLADNGJO_02195 3.59e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLADNGJO_02196 1.29e-211 - - - L - - - Phage integrase, N-terminal SAM-like domain
HLADNGJO_02197 1.46e-299 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HLADNGJO_02198 2.65e-53 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLADNGJO_02199 3.68e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HLADNGJO_02200 4.63e-275 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HLADNGJO_02201 2.29e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HLADNGJO_02202 4.37e-76 - - - M - - - Lysin motif
HLADNGJO_02203 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HLADNGJO_02204 1.34e-254 - - - S - - - Helix-turn-helix domain
HLADNGJO_02205 2.03e-112 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLADNGJO_02206 1.18e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HLADNGJO_02207 3.74e-130 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLADNGJO_02208 3.39e-182 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLADNGJO_02209 1.29e-88 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLADNGJO_02210 8.52e-175 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HLADNGJO_02211 6.26e-215 yitL - - S ko:K00243 - ko00000 S1 domain
HLADNGJO_02212 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HLADNGJO_02213 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HLADNGJO_02215 2.52e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HLADNGJO_02216 4.2e-202 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLADNGJO_02217 3.4e-163 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HLADNGJO_02218 5.64e-153 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HLADNGJO_02219 3.38e-293 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HLADNGJO_02220 7.39e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLADNGJO_02221 5.66e-277 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HLADNGJO_02222 1.1e-181 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLADNGJO_02223 3.12e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLADNGJO_02224 1.56e-278 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLADNGJO_02225 4.28e-113 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLADNGJO_02226 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLADNGJO_02227 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HLADNGJO_02228 7.15e-232 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLADNGJO_02229 1.36e-213 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLADNGJO_02230 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLADNGJO_02231 6.64e-154 - - - - - - - -
HLADNGJO_02232 1.55e-70 - - - - - - - -
HLADNGJO_02233 5.4e-69 - - - S - - - Cag pathogenicity island, type IV secretory system
HLADNGJO_02234 6.62e-133 - - - - - - - -
HLADNGJO_02235 4.26e-69 - - - - - - - -
HLADNGJO_02236 0.0 traA - - L - - - MobA MobL family protein
HLADNGJO_02237 5.67e-36 - - - - - - - -
HLADNGJO_02238 2.96e-55 - - - - - - - -
HLADNGJO_02239 5.68e-163 - - - S - - - protein conserved in bacteria
HLADNGJO_02240 5.93e-37 - - - - - - - -
HLADNGJO_02241 1.15e-57 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
HLADNGJO_02242 1.78e-209 repA - - S - - - Replication initiator protein A
HLADNGJO_02244 4.33e-190 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HLADNGJO_02245 7.2e-46 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
HLADNGJO_02247 4.18e-132 - - - - - - - -
HLADNGJO_02248 1.65e-102 - - - - - - - -
HLADNGJO_02249 7.28e-132 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HLADNGJO_02250 1.92e-122 - - - S - - - Serine hydrolase
HLADNGJO_02251 0.0 - - - M - - - Cna protein B-type domain
HLADNGJO_02253 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HLADNGJO_02254 2.76e-235 - - - L - - - Psort location Cytoplasmic, score
HLADNGJO_02255 3.79e-26 - - - - - - - -
HLADNGJO_02256 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HLADNGJO_02257 1.16e-84 - - - - - - - -
HLADNGJO_02258 1.98e-194 - - - - - - - -
HLADNGJO_02259 1.33e-82 - - - - - - - -
HLADNGJO_02260 0.0 traK - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
HLADNGJO_02262 1.82e-102 - - - - - - - -
HLADNGJO_02263 2.01e-123 - - - - - - - -
HLADNGJO_02264 4.77e-269 - - - M - - - CHAP domain
HLADNGJO_02265 5.42e-287 - - - S - - - WXG100 protein secretion system (Wss), protein YukC
HLADNGJO_02267 1.72e-26 - - - K - - - LytTr DNA-binding domain
HLADNGJO_02268 8.3e-36 - - - S - - - Protein of unknown function (DUF3021)
HLADNGJO_02269 1.53e-287 - - - L - - - MULE transposase domain
HLADNGJO_02270 6.71e-72 saeR - - T ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HLADNGJO_02271 2.6e-105 saeS 2.7.13.3 - T ko:K10681 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phospho-acceptor) domain
HLADNGJO_02272 2.74e-63 - - - - - - - -
HLADNGJO_02273 1.31e-287 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HLADNGJO_02274 1.25e-103 - - - S - - - Fic/DOC family
HLADNGJO_02275 1.42e-190 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HLADNGJO_02276 1.24e-66 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HLADNGJO_02277 0.0 traA - - L - - - MobA MobL family protein
HLADNGJO_02278 2.71e-34 - - - - - - - -
HLADNGJO_02279 5.7e-52 - - - - - - - -
HLADNGJO_02280 6.94e-59 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
HLADNGJO_02281 5.76e-189 repA - - S - - - Replication initiator protein A
HLADNGJO_02282 1.48e-50 - - - - - - - -
HLADNGJO_02283 6.41e-247 - - - NU - - - StbA protein
HLADNGJO_02284 2.21e-114 - - - L ko:K07497 - ko00000 hmm pf00665
HLADNGJO_02285 8.07e-18 - - - L - - - Winged helix-turn helix
HLADNGJO_02287 2.83e-58 - - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
HLADNGJO_02288 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HLADNGJO_02289 1.57e-74 usp2 - - T - - - Belongs to the universal stress protein A family
HLADNGJO_02290 8.93e-218 - - - L ko:K07497 - ko00000 Integrase core domain
HLADNGJO_02291 2.04e-61 - - - L ko:K07483 - ko00000 Transposase
HLADNGJO_02292 3.07e-123 tnpR1 - - L - - - Resolvase, N terminal domain
HLADNGJO_02293 7.18e-314 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HLADNGJO_02294 7.08e-108 pnuC - - H ko:K03811 - ko00000,ko02000 Nicotinamide mononucleotide transporter
HLADNGJO_02295 0.0 - - - M - - - Cna protein B-type domain
HLADNGJO_02296 2.02e-148 - - - - - - - -
HLADNGJO_02297 2.31e-11 - - - S - - - Helix-turn-helix of DDE superfamily endonuclease
HLADNGJO_02298 1.15e-46 - - - L - - - Integrase
HLADNGJO_02299 5.8e-50 - - - S - - - SnoaL-like domain
HLADNGJO_02300 4.49e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
HLADNGJO_02301 1.26e-73 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLADNGJO_02302 1.27e-39 - - - L - - - Integrase
HLADNGJO_02305 6.06e-51 - - - IU - - - cell wall organization
HLADNGJO_02307 0.0 essC - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
HLADNGJO_02308 4.72e-82 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HLADNGJO_02311 1.23e-130 esaA - - V - - - type VII secretion protein EsaA
HLADNGJO_02312 5.7e-28 - - - S - - - Proteins of 100 residues with WXG
HLADNGJO_02313 4.14e-108 - - - M - - - LysM domain protein
HLADNGJO_02314 0.0 traA - - L - - - MobA MobL family protein
HLADNGJO_02315 3.36e-42 - - - - - - - -
HLADNGJO_02316 9.59e-216 - 2.7.1.176 - S ko:K16214 - ko00000,ko01000,ko02048 Zeta toxin
HLADNGJO_02317 6.53e-58 - - - S - - - Bacterial epsilon antitoxin
HLADNGJO_02318 6.17e-55 - - - - - - - -
HLADNGJO_02319 4.9e-222 repA - - S - - - Replication initiator protein A
HLADNGJO_02321 7.02e-58 - - - - - - - -
HLADNGJO_02322 2.24e-247 - - - NU - - - StbA protein
HLADNGJO_02323 5.92e-55 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
HLADNGJO_02324 1.6e-138 - - - K - - - Bacterial regulatory proteins, tetR family
HLADNGJO_02325 0.0 - - - EGP - - - Major Facilitator
HLADNGJO_02326 2.29e-295 - - - E - - - X-Pro dipeptidyl-peptidase (S15 family)
HLADNGJO_02327 9.9e-09 - - - T - - - Response regulator receiver domain protein
HLADNGJO_02328 2.51e-59 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)