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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HLCLCPOC_00001	8.95e-315	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLCLCPOC_00002	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLCLCPOC_00003	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HLCLCPOC_00004	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLCLCPOC_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLCLCPOC_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLCLCPOC_00007	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HLCLCPOC_00008	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLCLCPOC_00009	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLCLCPOC_00010	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HLCLCPOC_00011	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HLCLCPOC_00012	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HLCLCPOC_00013	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HLCLCPOC_00014	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLCLCPOC_00015	1.88e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLCLCPOC_00017	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HLCLCPOC_00018	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HLCLCPOC_00019	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HLCLCPOC_00020	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HLCLCPOC_00021	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HLCLCPOC_00022	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HLCLCPOC_00023	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HLCLCPOC_00025	2.4e-183	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HLCLCPOC_00026	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HLCLCPOC_00027	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HLCLCPOC_00028	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HLCLCPOC_00029	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HLCLCPOC_00030	2.54e-50	-	-	-	-	-	-	-	-
HLCLCPOC_00032	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HLCLCPOC_00033	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLCLCPOC_00034	1.02e-312	yycH	-	-	S	-	-	-	YycH protein
HLCLCPOC_00035	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HLCLCPOC_00036	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HLCLCPOC_00037	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HLCLCPOC_00038	1.74e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLCLCPOC_00039	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_00040	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HLCLCPOC_00041	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HLCLCPOC_00042	2.24e-155	pnb	-	-	C	-	-	-	nitroreductase
HLCLCPOC_00043	2.02e-85	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HLCLCPOC_00044	5.25e-149	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HLCLCPOC_00045	0.0	-	-	-	C	-	-	-	FMN_bind
HLCLCPOC_00046	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HLCLCPOC_00047	8.51e-107	-	-	-	K	-	-	-	LysR family
HLCLCPOC_00048	4.28e-83	-	-	-	K	-	-	-	LysR family
HLCLCPOC_00049	2.49e-95	-	-	-	C	-	-	-	FMN binding
HLCLCPOC_00050	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLCLCPOC_00051	4.06e-211	-	-	-	S	-	-	-	KR domain
HLCLCPOC_00052	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HLCLCPOC_00053	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HLCLCPOC_00054	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HLCLCPOC_00055	3.83e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HLCLCPOC_00056	6.27e-248	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLCLCPOC_00057	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HLCLCPOC_00058	3.97e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HLCLCPOC_00059	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HLCLCPOC_00060	1.65e-106	-	-	-	S	-	-	-	ASCH
HLCLCPOC_00061	3.06e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HLCLCPOC_00062	1.67e-220	-	-	-	K	-	-	-	WYL domain
HLCLCPOC_00063	1.34e-151	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLCLCPOC_00064	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HLCLCPOC_00065	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HLCLCPOC_00066	1.9e-79	-	-	-	S	-	-	-	Protein of unknown function
HLCLCPOC_00067	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HLCLCPOC_00068	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HLCLCPOC_00069	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HLCLCPOC_00070	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HLCLCPOC_00071	3.49e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLCLCPOC_00072	1.71e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HLCLCPOC_00073	2.58e-214	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HLCLCPOC_00074	9.06e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HLCLCPOC_00075	2.38e-99	-	-	-	-	-	-	-	-
HLCLCPOC_00076	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HLCLCPOC_00077	3.42e-180	-	-	-	-	-	-	-	-
HLCLCPOC_00078	4.07e-05	-	-	-	-	-	-	-	-
HLCLCPOC_00079	3.67e-180	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HLCLCPOC_00080	1.67e-54	-	-	-	-	-	-	-	-
HLCLCPOC_00081	3.52e-165	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLCLCPOC_00082	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HLCLCPOC_00083	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HLCLCPOC_00084	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HLCLCPOC_00085	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HLCLCPOC_00086	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HLCLCPOC_00087	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HLCLCPOC_00088	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HLCLCPOC_00089	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLCLCPOC_00090	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HLCLCPOC_00091	3.94e-224	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HLCLCPOC_00092	1.79e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLCLCPOC_00093	3.03e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLCLCPOC_00094	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLCLCPOC_00095	1.97e-259	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HLCLCPOC_00096	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HLCLCPOC_00097	0.0	-	-	-	L	-	-	-	HIRAN domain
HLCLCPOC_00098	3.55e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HLCLCPOC_00099	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HLCLCPOC_00100	1.73e-157	-	-	-	-	-	-	-	-
HLCLCPOC_00101	4.17e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HLCLCPOC_00102	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HLCLCPOC_00103	2.48e-199	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLCLCPOC_00104	2.81e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLCLCPOC_00105	2.44e-127	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HLCLCPOC_00106	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HLCLCPOC_00107	8.08e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
HLCLCPOC_00108	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HLCLCPOC_00109	1.47e-143	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HLCLCPOC_00110	9.35e-101	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_00111	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLCLCPOC_00112	1.11e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HLCLCPOC_00113	4.46e-88	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLCLCPOC_00114	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HLCLCPOC_00115	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLCLCPOC_00116	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HLCLCPOC_00118	2.16e-204	morA	-	-	S	-	-	-	reductase
HLCLCPOC_00119	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HLCLCPOC_00120	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HLCLCPOC_00121	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HLCLCPOC_00122	6.97e-126	-	-	-	-	-	-	-	-
HLCLCPOC_00123	0.0	-	-	-	-	-	-	-	-
HLCLCPOC_00124	4.2e-264	-	-	-	C	-	-	-	Oxidoreductase
HLCLCPOC_00125	4.46e-191	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HLCLCPOC_00126	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_00127	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HLCLCPOC_00129	3.08e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HLCLCPOC_00130	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HLCLCPOC_00131	6.34e-182	-	-	-	-	-	-	-	-
HLCLCPOC_00132	3.16e-191	-	-	-	-	-	-	-	-
HLCLCPOC_00133	3.37e-115	-	-	-	-	-	-	-	-
HLCLCPOC_00134	7.14e-185	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HLCLCPOC_00135	4.07e-216	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_00136	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HLCLCPOC_00137	9.77e-152	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HLCLCPOC_00138	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HLCLCPOC_00139	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HLCLCPOC_00141	5.29e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_00142	2.74e-242	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HLCLCPOC_00143	1.58e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HLCLCPOC_00144	3.9e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HLCLCPOC_00145	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HLCLCPOC_00146	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLCLCPOC_00147	1.08e-244	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLCLCPOC_00148	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HLCLCPOC_00149	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HLCLCPOC_00150	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLCLCPOC_00151	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLCLCPOC_00152	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLCLCPOC_00153	1.01e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HLCLCPOC_00154	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HLCLCPOC_00155	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLCLCPOC_00156	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HLCLCPOC_00157	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HLCLCPOC_00158	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HLCLCPOC_00159	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HLCLCPOC_00160	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HLCLCPOC_00161	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLCLCPOC_00162	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HLCLCPOC_00163	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLCLCPOC_00164	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HLCLCPOC_00165	9.92e-212	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HLCLCPOC_00166	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HLCLCPOC_00167	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HLCLCPOC_00168	1.41e-158	mleR	-	-	K	-	-	-	LysR substrate binding domain
HLCLCPOC_00169	0.0	-	-	-	M	-	-	-	domain protein
HLCLCPOC_00171	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HLCLCPOC_00172	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HLCLCPOC_00173	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HLCLCPOC_00174	9.25e-103	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HLCLCPOC_00175	1.69e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLCLCPOC_00176	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HLCLCPOC_00177	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HLCLCPOC_00178	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HLCLCPOC_00179	6.33e-46	-	-	-	-	-	-	-	-
HLCLCPOC_00180	1.81e-15	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HLCLCPOC_00181	1.46e-206	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HLCLCPOC_00182	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLCLCPOC_00183	3.81e-18	-	-	-	-	-	-	-	-
HLCLCPOC_00184	5.08e-74	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLCLCPOC_00185	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLCLCPOC_00186	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HLCLCPOC_00187	2.13e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HLCLCPOC_00188	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLCLCPOC_00189	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HLCLCPOC_00190	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HLCLCPOC_00191	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HLCLCPOC_00192	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLCLCPOC_00193	4.02e-90	-	-	-	-	-	-	-	-
HLCLCPOC_00194	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HLCLCPOC_00195	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLCLCPOC_00196	2.22e-221	-	-	-	P	-	-	-	Major Facilitator Superfamily
HLCLCPOC_00197	7.88e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HLCLCPOC_00198	2.46e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HLCLCPOC_00199	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLCLCPOC_00200	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HLCLCPOC_00201	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HLCLCPOC_00202	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_00203	2.61e-282	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HLCLCPOC_00204	2.43e-111	-	-	-	-	-	-	-	-
HLCLCPOC_00205	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HLCLCPOC_00206	7.19e-68	-	-	-	-	-	-	-	-
HLCLCPOC_00207	1.22e-125	-	-	-	-	-	-	-	-
HLCLCPOC_00208	2.98e-90	-	-	-	-	-	-	-	-
HLCLCPOC_00209	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HLCLCPOC_00210	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HLCLCPOC_00211	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HLCLCPOC_00212	2.8e-161	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HLCLCPOC_00213	4.99e-296	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_00214	3.56e-52	-	-	-	-	-	-	-	-
HLCLCPOC_00215	2.18e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HLCLCPOC_00216	6.28e-272	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HLCLCPOC_00217	8.38e-258	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HLCLCPOC_00218	1.75e-51	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HLCLCPOC_00219	1.45e-93	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HLCLCPOC_00220	1.17e-244	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HLCLCPOC_00221	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HLCLCPOC_00222	1e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HLCLCPOC_00223	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HLCLCPOC_00224	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HLCLCPOC_00225	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HLCLCPOC_00226	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HLCLCPOC_00227	2.21e-56	-	-	-	-	-	-	-	-
HLCLCPOC_00228	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HLCLCPOC_00229	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HLCLCPOC_00230	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLCLCPOC_00231	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HLCLCPOC_00232	2.6e-185	-	-	-	-	-	-	-	-
HLCLCPOC_00233	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HLCLCPOC_00234	4.5e-303	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HLCLCPOC_00235	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLCLCPOC_00236	1.3e-203	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HLCLCPOC_00237	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HLCLCPOC_00238	9.53e-93	-	-	-	-	-	-	-	-
HLCLCPOC_00239	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_00240	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_00241	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLCLCPOC_00242	1.15e-152	-	-	-	-	-	-	-	-
HLCLCPOC_00243	2.92e-57	-	-	-	-	-	-	-	-
HLCLCPOC_00244	1.55e-55	-	-	-	-	-	-	-	-
HLCLCPOC_00245	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HLCLCPOC_00246	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLCLCPOC_00247	0.0	hpk2	-	-	T	-	-	-	Histidine kinase
HLCLCPOC_00248	1.1e-164	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HLCLCPOC_00249	2.42e-65	-	-	-	-	-	-	-	-
HLCLCPOC_00250	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HLCLCPOC_00251	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_00252	3.35e-75	-	-	-	-	-	-	-	-
HLCLCPOC_00253	2.87e-56	-	-	-	-	-	-	-	-
HLCLCPOC_00254	7.18e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLCLCPOC_00255	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HLCLCPOC_00256	1.49e-63	-	-	-	-	-	-	-	-
HLCLCPOC_00257	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HLCLCPOC_00258	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HLCLCPOC_00259	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HLCLCPOC_00260	3.39e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HLCLCPOC_00261	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HLCLCPOC_00262	1.84e-295	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HLCLCPOC_00263	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_00264	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_00265	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_00266	3.42e-76	-	-	-	M	-	-	-	Lysin motif
HLCLCPOC_00267	2.31e-95	-	-	-	M	-	-	-	LysM domain protein
HLCLCPOC_00268	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HLCLCPOC_00269	5.01e-226	-	-	-	-	-	-	-	-
HLCLCPOC_00270	2.8e-169	-	-	-	-	-	-	-	-
HLCLCPOC_00271	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HLCLCPOC_00272	2.04e-73	-	-	-	-	-	-	-	-
HLCLCPOC_00273	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLCLCPOC_00274	1.79e-100	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HLCLCPOC_00275	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_00276	1.17e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HLCLCPOC_00277	1.79e-52	-	-	-	-	-	-	-	-
HLCLCPOC_00278	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLCLCPOC_00279	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLCLCPOC_00280	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLCLCPOC_00281	5.09e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HLCLCPOC_00282	4.3e-124	-	-	-	K	-	-	-	Cupin domain
HLCLCPOC_00283	8.08e-110	-	-	-	S	-	-	-	ASCH
HLCLCPOC_00284	1.88e-111	-	-	-	K	-	-	-	GNAT family
HLCLCPOC_00285	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
HLCLCPOC_00286	2.06e-30	-	-	-	-	-	-	-	-
HLCLCPOC_00287	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HLCLCPOC_00288	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLCLCPOC_00289	1.08e-243	-	-	-	-	-	-	-	-
HLCLCPOC_00290	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HLCLCPOC_00291	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HLCLCPOC_00293	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HLCLCPOC_00294	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HLCLCPOC_00295	7.28e-42	-	-	-	-	-	-	-	-
HLCLCPOC_00296	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLCLCPOC_00297	6.4e-54	-	-	-	-	-	-	-	-
HLCLCPOC_00298	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HLCLCPOC_00299	2.48e-226	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLCLCPOC_00300	6.71e-80	-	-	-	S	-	-	-	CHY zinc finger
HLCLCPOC_00301	1.63e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLCLCPOC_00302	1.06e-278	-	-	-	-	-	-	-	-
HLCLCPOC_00303	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HLCLCPOC_00304	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HLCLCPOC_00305	3.93e-59	-	-	-	-	-	-	-	-
HLCLCPOC_00306	9.1e-112	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HLCLCPOC_00307	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HLCLCPOC_00308	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HLCLCPOC_00309	9e-227	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HLCLCPOC_00310	8.95e-60	-	-	-	-	-	-	-	-
HLCLCPOC_00311	3.51e-131	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HLCLCPOC_00312	6.87e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HLCLCPOC_00313	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HLCLCPOC_00314	1.08e-71	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HLCLCPOC_00315	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HLCLCPOC_00316	3.79e-293	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HLCLCPOC_00317	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HLCLCPOC_00318	1.52e-103	-	-	-	-	-	-	-	-
HLCLCPOC_00319	9.88e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLCLCPOC_00320	3.66e-224	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HLCLCPOC_00321	4.01e-206	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLCLCPOC_00322	1.17e-101	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HLCLCPOC_00323	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLCLCPOC_00324	4.47e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_00325	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HLCLCPOC_00326	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLCLCPOC_00327	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HLCLCPOC_00328	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLCLCPOC_00329	0.0	-	-	-	M	-	-	-	domain protein
HLCLCPOC_00330	1.12e-72	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HLCLCPOC_00332	2e-44	-	-	-	-	-	-	-	-
HLCLCPOC_00334	8.72e-24	-	-	-	-	-	-	-	-
HLCLCPOC_00335	3.27e-81	-	-	-	-	-	-	-	-
HLCLCPOC_00337	1.08e-152	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HLCLCPOC_00338	7.81e-263	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HLCLCPOC_00339	3.41e-187	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HLCLCPOC_00340	9.59e-212	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_00341	8.38e-192	-	-	-	S	-	-	-	hydrolase
HLCLCPOC_00342	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLCLCPOC_00343	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLCLCPOC_00346	3.81e-150	-	-	-	-	-	-	-	-
HLCLCPOC_00348	1.32e-141	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HLCLCPOC_00349	5.61e-169	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HLCLCPOC_00350	3.32e-166	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_00351	1.93e-31	plnF	-	-	-	-	-	-	-
HLCLCPOC_00352	8.82e-32	-	-	-	-	-	-	-	-
HLCLCPOC_00353	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HLCLCPOC_00354	6.78e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HLCLCPOC_00355	1.57e-141	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_00356	3.26e-151	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_00357	1.46e-140	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_00358	6.46e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_00359	5.5e-42	-	-	-	-	-	-	-	-
HLCLCPOC_00360	0.0	-	-	-	L	-	-	-	DNA helicase
HLCLCPOC_00361	5.87e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HLCLCPOC_00362	1.36e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLCLCPOC_00363	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HLCLCPOC_00364	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_00365	9.68e-34	-	-	-	-	-	-	-	-
HLCLCPOC_00366	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HLCLCPOC_00367	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_00368	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLCLCPOC_00369	6.97e-209	-	-	-	GK	-	-	-	ROK family
HLCLCPOC_00370	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HLCLCPOC_00371	3.43e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLCLCPOC_00372	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HLCLCPOC_00373	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HLCLCPOC_00374	1.82e-226	-	-	-	-	-	-	-	-
HLCLCPOC_00375	1.24e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HLCLCPOC_00376	3.74e-204	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HLCLCPOC_00377	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HLCLCPOC_00378	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLCLCPOC_00379	2.48e-203	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HLCLCPOC_00380	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HLCLCPOC_00381	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLCLCPOC_00382	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLCLCPOC_00383	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HLCLCPOC_00384	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLCLCPOC_00385	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HLCLCPOC_00386	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLCLCPOC_00387	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HLCLCPOC_00388	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HLCLCPOC_00389	1.34e-297	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLCLCPOC_00390	2.82e-196	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HLCLCPOC_00391	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLCLCPOC_00392	1.82e-232	-	-	-	S	-	-	-	DUF218 domain
HLCLCPOC_00393	3.53e-178	-	-	-	-	-	-	-	-
HLCLCPOC_00394	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
HLCLCPOC_00395	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HLCLCPOC_00396	2.68e-201	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HLCLCPOC_00397	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HLCLCPOC_00398	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLCLCPOC_00399	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLCLCPOC_00400	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLCLCPOC_00401	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HLCLCPOC_00402	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HLCLCPOC_00403	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HLCLCPOC_00404	2.3e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HLCLCPOC_00405	2.41e-37	-	-	-	-	-	-	-	-
HLCLCPOC_00406	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLCLCPOC_00407	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLCLCPOC_00408	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HLCLCPOC_00409	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
HLCLCPOC_00410	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HLCLCPOC_00411	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HLCLCPOC_00412	5.58e-195	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HLCLCPOC_00413	1.84e-189	-	-	-	-	-	-	-	-
HLCLCPOC_00414	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLCLCPOC_00415	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLCLCPOC_00416	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLCLCPOC_00417	1.43e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLCLCPOC_00418	4.28e-84	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HLCLCPOC_00419	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HLCLCPOC_00420	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HLCLCPOC_00421	3.03e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLCLCPOC_00422	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLCLCPOC_00423	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HLCLCPOC_00424	1.06e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HLCLCPOC_00425	1.79e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HLCLCPOC_00426	9.73e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HLCLCPOC_00427	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HLCLCPOC_00428	5.21e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HLCLCPOC_00429	2.63e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLCLCPOC_00430	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HLCLCPOC_00431	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HLCLCPOC_00432	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HLCLCPOC_00433	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLCLCPOC_00434	8.29e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLCLCPOC_00435	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLCLCPOC_00436	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HLCLCPOC_00437	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HLCLCPOC_00439	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HLCLCPOC_00440	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HLCLCPOC_00441	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLCLCPOC_00442	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HLCLCPOC_00443	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLCLCPOC_00444	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLCLCPOC_00445	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLCLCPOC_00446	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HLCLCPOC_00449	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HLCLCPOC_00452	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HLCLCPOC_00453	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLCLCPOC_00457	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HLCLCPOC_00458	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HLCLCPOC_00459	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HLCLCPOC_00460	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
HLCLCPOC_00461	4.33e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HLCLCPOC_00462	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLCLCPOC_00463	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLCLCPOC_00464	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HLCLCPOC_00465	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HLCLCPOC_00466	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLCLCPOC_00467	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLCLCPOC_00468	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HLCLCPOC_00469	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HLCLCPOC_00470	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HLCLCPOC_00471	3.76e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HLCLCPOC_00472	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HLCLCPOC_00473	1.19e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLCLCPOC_00475	3.36e-199	-	-	-	G	-	-	-	Peptidase_C39 like family
HLCLCPOC_00476	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HLCLCPOC_00477	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HLCLCPOC_00478	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HLCLCPOC_00479	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HLCLCPOC_00480	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HLCLCPOC_00481	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HLCLCPOC_00482	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HLCLCPOC_00483	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLCLCPOC_00484	2.18e-83	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HLCLCPOC_00485	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HLCLCPOC_00486	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLCLCPOC_00487	4.1e-176	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HLCLCPOC_00488	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLCLCPOC_00489	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HLCLCPOC_00490	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HLCLCPOC_00491	1.11e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLCLCPOC_00492	1.12e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HLCLCPOC_00493	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HLCLCPOC_00494	1.33e-157	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLCLCPOC_00495	8.47e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HLCLCPOC_00496	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HLCLCPOC_00497	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLCLCPOC_00498	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HLCLCPOC_00499	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLCLCPOC_00500	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLCLCPOC_00501	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLCLCPOC_00502	2.48e-176	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLCLCPOC_00503	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HLCLCPOC_00504	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HLCLCPOC_00505	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLCLCPOC_00506	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLCLCPOC_00507	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HLCLCPOC_00508	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLCLCPOC_00509	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLCLCPOC_00510	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLCLCPOC_00511	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLCLCPOC_00512	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLCLCPOC_00513	5.22e-229	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HLCLCPOC_00514	1.46e-87	-	-	-	L	-	-	-	nuclease
HLCLCPOC_00515	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLCLCPOC_00516	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HLCLCPOC_00517	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLCLCPOC_00518	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLCLCPOC_00519	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HLCLCPOC_00520	1.11e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HLCLCPOC_00521	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLCLCPOC_00522	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLCLCPOC_00523	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLCLCPOC_00524	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLCLCPOC_00525	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HLCLCPOC_00526	6.36e-153	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLCLCPOC_00527	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HLCLCPOC_00528	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLCLCPOC_00529	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HLCLCPOC_00530	1.53e-212	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLCLCPOC_00531	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HLCLCPOC_00532	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HLCLCPOC_00533	8.87e-269	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HLCLCPOC_00534	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HLCLCPOC_00535	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLCLCPOC_00536	2.65e-177	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HLCLCPOC_00537	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HLCLCPOC_00538	2.84e-241	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HLCLCPOC_00539	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HLCLCPOC_00540	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HLCLCPOC_00541	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HLCLCPOC_00542	7.63e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLCLCPOC_00543	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HLCLCPOC_00544	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLCLCPOC_00545	1.68e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_00546	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLCLCPOC_00547	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLCLCPOC_00548	0.0	ydaO	-	-	E	-	-	-	amino acid
HLCLCPOC_00549	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HLCLCPOC_00550	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HLCLCPOC_00551	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HLCLCPOC_00552	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HLCLCPOC_00553	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HLCLCPOC_00554	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLCLCPOC_00555	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLCLCPOC_00556	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLCLCPOC_00557	1.28e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HLCLCPOC_00558	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HLCLCPOC_00559	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLCLCPOC_00560	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HLCLCPOC_00561	2.22e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HLCLCPOC_00562	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HLCLCPOC_00563	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLCLCPOC_00564	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLCLCPOC_00565	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HLCLCPOC_00566	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HLCLCPOC_00567	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HLCLCPOC_00568	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLCLCPOC_00569	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLCLCPOC_00570	1.15e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HLCLCPOC_00571	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HLCLCPOC_00572	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HLCLCPOC_00573	0.0	nox	-	-	C	-	-	-	NADH oxidase
HLCLCPOC_00574	3.69e-206	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HLCLCPOC_00575	2.45e-310	-	-	-	-	-	-	-	-
HLCLCPOC_00576	8.36e-257	-	-	-	S	-	-	-	Protein conserved in bacteria
HLCLCPOC_00577	2.74e-277	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HLCLCPOC_00578	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HLCLCPOC_00579	8.49e-138	-	-	-	T	-	-	-	diguanylate cyclase activity
HLCLCPOC_00580	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLCLCPOC_00581	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HLCLCPOC_00582	4.7e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HLCLCPOC_00583	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HLCLCPOC_00584	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HLCLCPOC_00585	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HLCLCPOC_00586	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HLCLCPOC_00587	8.83e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HLCLCPOC_00588	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HLCLCPOC_00589	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLCLCPOC_00590	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLCLCPOC_00591	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLCLCPOC_00592	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLCLCPOC_00593	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HLCLCPOC_00594	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HLCLCPOC_00595	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HLCLCPOC_00596	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HLCLCPOC_00597	7e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HLCLCPOC_00598	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HLCLCPOC_00599	6.3e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLCLCPOC_00600	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLCLCPOC_00602	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HLCLCPOC_00603	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HLCLCPOC_00604	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLCLCPOC_00605	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HLCLCPOC_00606	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLCLCPOC_00607	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLCLCPOC_00608	5.11e-171	-	-	-	-	-	-	-	-
HLCLCPOC_00609	7.83e-142	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HLCLCPOC_00610	2.67e-198	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HLCLCPOC_00611	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HLCLCPOC_00612	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HLCLCPOC_00613	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLCLCPOC_00614	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLCLCPOC_00615	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HLCLCPOC_00616	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLCLCPOC_00617	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_00618	6.57e-136	-	-	-	-	-	-	-	-
HLCLCPOC_00619	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HLCLCPOC_00620	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLCLCPOC_00621	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HLCLCPOC_00622	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HLCLCPOC_00623	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HLCLCPOC_00624	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLCLCPOC_00625	8.47e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HLCLCPOC_00626	1.71e-210	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HLCLCPOC_00627	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HLCLCPOC_00628	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLCLCPOC_00629	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLCLCPOC_00630	5.68e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HLCLCPOC_00631	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLCLCPOC_00632	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HLCLCPOC_00633	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLCLCPOC_00634	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLCLCPOC_00635	3.15e-158	-	-	-	T	-	-	-	EAL domain
HLCLCPOC_00636	9.79e-191	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HLCLCPOC_00637	4.22e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_00638	1.7e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HLCLCPOC_00639	3.38e-70	-	-	-	-	-	-	-	-
HLCLCPOC_00640	2.49e-95	-	-	-	-	-	-	-	-
HLCLCPOC_00641	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HLCLCPOC_00642	7.34e-180	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HLCLCPOC_00643	1.15e-41	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HLCLCPOC_00644	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLCLCPOC_00645	4.13e-182	-	-	-	-	-	-	-	-
HLCLCPOC_00647	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HLCLCPOC_00648	3.88e-46	-	-	-	-	-	-	-	-
HLCLCPOC_00649	2.08e-117	-	-	-	V	-	-	-	VanZ like family
HLCLCPOC_00650	1.06e-314	-	-	-	EGP	-	-	-	Major Facilitator
HLCLCPOC_00651	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HLCLCPOC_00652	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HLCLCPOC_00653	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HLCLCPOC_00654	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HLCLCPOC_00655	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_00656	1.36e-27	-	-	-	-	-	-	-	-
HLCLCPOC_00657	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLCLCPOC_00658	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HLCLCPOC_00659	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HLCLCPOC_00660	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HLCLCPOC_00661	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HLCLCPOC_00662	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLCLCPOC_00663	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HLCLCPOC_00664	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HLCLCPOC_00665	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
HLCLCPOC_00666	1.09e-60	-	-	-	-	-	-	-	-
HLCLCPOC_00667	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HLCLCPOC_00668	6.12e-115	-	-	-	-	-	-	-	-
HLCLCPOC_00669	7.76e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HLCLCPOC_00670	3.05e-95	-	-	-	F	-	-	-	Nudix hydrolase
HLCLCPOC_00671	1.48e-27	-	-	-	-	-	-	-	-
HLCLCPOC_00672	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HLCLCPOC_00673	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HLCLCPOC_00674	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HLCLCPOC_00675	1.01e-188	-	-	-	-	-	-	-	-
HLCLCPOC_00676	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HLCLCPOC_00677	1.86e-267	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLCLCPOC_00678	5.1e-218	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLCLCPOC_00679	1.28e-54	-	-	-	-	-	-	-	-
HLCLCPOC_00681	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_00682	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLCLCPOC_00683	1.81e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLCLCPOC_00684	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLCLCPOC_00685	1e-107	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HLCLCPOC_00686	1.34e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HLCLCPOC_00687	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HLCLCPOC_00688	1.24e-179	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HLCLCPOC_00689	8.73e-315	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HLCLCPOC_00690	2.55e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLCLCPOC_00691	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HLCLCPOC_00692	3.08e-93	-	-	-	K	-	-	-	MarR family
HLCLCPOC_00693	8.85e-267	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLCLCPOC_00694	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLCLCPOC_00695	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_00696	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLCLCPOC_00697	1.88e-101	rppH3	-	-	F	-	-	-	NUDIX domain
HLCLCPOC_00698	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HLCLCPOC_00699	1.61e-36	-	-	-	-	-	-	-	-
HLCLCPOC_00700	2.23e-164	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HLCLCPOC_00701	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HLCLCPOC_00702	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HLCLCPOC_00703	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HLCLCPOC_00704	2.84e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HLCLCPOC_00705	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLCLCPOC_00706	3.59e-212	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HLCLCPOC_00707	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HLCLCPOC_00708	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HLCLCPOC_00710	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
HLCLCPOC_00712	4.77e-48	-	-	-	L	-	-	-	Helix-turn-helix domain
HLCLCPOC_00713	1.51e-22	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLCLCPOC_00714	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLCLCPOC_00715	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLCLCPOC_00716	1.38e-75	-	-	-	-	-	-	-	-
HLCLCPOC_00717	1.08e-71	-	-	-	-	-	-	-	-
HLCLCPOC_00718	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HLCLCPOC_00719	1.16e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_00720	3.08e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HLCLCPOC_00721	1.92e-301	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HLCLCPOC_00722	3.5e-299	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HLCLCPOC_00723	3.61e-61	-	-	-	S	-	-	-	MORN repeat
HLCLCPOC_00724	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HLCLCPOC_00725	7.38e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HLCLCPOC_00726	1.95e-116	-	-	-	-	-	-	-	-
HLCLCPOC_00727	5.74e-32	-	-	-	-	-	-	-	-
HLCLCPOC_00728	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HLCLCPOC_00729	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HLCLCPOC_00730	1.59e-189	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HLCLCPOC_00731	4.2e-208	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HLCLCPOC_00732	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HLCLCPOC_00733	2.19e-131	-	-	-	G	-	-	-	Glycogen debranching enzyme
HLCLCPOC_00734	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HLCLCPOC_00735	4.37e-108	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HLCLCPOC_00736	1.5e-285	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HLCLCPOC_00737	3.37e-60	-	-	-	S	-	-	-	MazG-like family
HLCLCPOC_00738	2.31e-117	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HLCLCPOC_00739	0.0	-	-	-	M	-	-	-	MucBP domain
HLCLCPOC_00740	1.42e-08	-	-	-	-	-	-	-	-
HLCLCPOC_00741	1.27e-115	-	-	-	S	-	-	-	AAA domain
HLCLCPOC_00742	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
HLCLCPOC_00743	1.09e-123	-	-	-	K	-	-	-	Helix-turn-helix domain
HLCLCPOC_00744	1.6e-219	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_00745	0.0	-	-	-	C	-	-	-	FMN_bind
HLCLCPOC_00747	3.54e-105	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_00748	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLCLCPOC_00749	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HLCLCPOC_00750	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HLCLCPOC_00751	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLCLCPOC_00752	1.08e-289	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HLCLCPOC_00753	5.44e-56	-	-	-	-	-	-	-	-
HLCLCPOC_00754	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HLCLCPOC_00755	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HLCLCPOC_00756	1.36e-208	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLCLCPOC_00757	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLCLCPOC_00758	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HLCLCPOC_00759	1.12e-243	-	-	-	-	-	-	-	-
HLCLCPOC_00760	3.28e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HLCLCPOC_00761	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HLCLCPOC_00762	4.77e-130	-	-	-	K	-	-	-	FR47-like protein
HLCLCPOC_00763	1.76e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HLCLCPOC_00764	7.32e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLCLCPOC_00765	0.0	xylP2	-	-	G	-	-	-	symporter
HLCLCPOC_00766	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLCLCPOC_00767	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HLCLCPOC_00768	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLCLCPOC_00769	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HLCLCPOC_00770	4.09e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HLCLCPOC_00771	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HLCLCPOC_00772	5.73e-114	-	-	-	-	-	-	-	-
HLCLCPOC_00773	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HLCLCPOC_00774	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HLCLCPOC_00775	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HLCLCPOC_00776	1.36e-77	-	-	-	-	-	-	-	-
HLCLCPOC_00777	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HLCLCPOC_00778	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HLCLCPOC_00779	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HLCLCPOC_00780	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HLCLCPOC_00781	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLCLCPOC_00782	2.05e-153	-	-	-	I	-	-	-	phosphatase
HLCLCPOC_00783	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLCLCPOC_00784	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HLCLCPOC_00785	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_00786	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLCLCPOC_00787	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HLCLCPOC_00788	1.06e-152	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HLCLCPOC_00789	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HLCLCPOC_00790	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLCLCPOC_00791	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLCLCPOC_00799	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HLCLCPOC_00800	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLCLCPOC_00801	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_00802	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLCLCPOC_00803	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLCLCPOC_00804	8.58e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HLCLCPOC_00805	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLCLCPOC_00806	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLCLCPOC_00807	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLCLCPOC_00808	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HLCLCPOC_00809	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLCLCPOC_00810	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HLCLCPOC_00811	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLCLCPOC_00812	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLCLCPOC_00813	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLCLCPOC_00814	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLCLCPOC_00815	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLCLCPOC_00816	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLCLCPOC_00817	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HLCLCPOC_00818	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLCLCPOC_00819	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLCLCPOC_00820	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLCLCPOC_00821	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLCLCPOC_00822	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLCLCPOC_00823	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLCLCPOC_00824	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLCLCPOC_00825	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLCLCPOC_00826	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HLCLCPOC_00827	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HLCLCPOC_00828	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLCLCPOC_00829	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLCLCPOC_00830	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLCLCPOC_00831	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLCLCPOC_00832	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLCLCPOC_00833	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLCLCPOC_00834	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HLCLCPOC_00835	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLCLCPOC_00836	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HLCLCPOC_00837	5.37e-112	-	-	-	S	-	-	-	NusG domain II
HLCLCPOC_00838	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HLCLCPOC_00839	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HLCLCPOC_00840	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLCLCPOC_00841	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLCLCPOC_00842	2.85e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLCLCPOC_00843	9.72e-184	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLCLCPOC_00844	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLCLCPOC_00845	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLCLCPOC_00846	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HLCLCPOC_00847	2.44e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HLCLCPOC_00848	1e-234	-	-	-	S	-	-	-	Membrane
HLCLCPOC_00849	2.61e-259	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HLCLCPOC_00850	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLCLCPOC_00851	2.35e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLCLCPOC_00852	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HLCLCPOC_00853	1.23e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HLCLCPOC_00854	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HLCLCPOC_00855	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HLCLCPOC_00856	2.01e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HLCLCPOC_00857	3.01e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HLCLCPOC_00858	6.33e-254	-	-	-	K	-	-	-	Helix-turn-helix domain
HLCLCPOC_00859	9.07e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HLCLCPOC_00860	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLCLCPOC_00861	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HLCLCPOC_00862	3e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLCLCPOC_00863	1.18e-66	-	-	-	-	-	-	-	-
HLCLCPOC_00864	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLCLCPOC_00865	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HLCLCPOC_00866	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HLCLCPOC_00867	5.51e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HLCLCPOC_00868	2.52e-240	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HLCLCPOC_00869	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HLCLCPOC_00870	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HLCLCPOC_00871	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HLCLCPOC_00873	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLCLCPOC_00874	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HLCLCPOC_00875	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HLCLCPOC_00876	4.35e-205	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HLCLCPOC_00877	6.5e-215	mleR	-	-	K	-	-	-	LysR family
HLCLCPOC_00878	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HLCLCPOC_00879	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HLCLCPOC_00880	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HLCLCPOC_00881	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HLCLCPOC_00882	2.56e-34	-	-	-	-	-	-	-	-
HLCLCPOC_00883	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HLCLCPOC_00884	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HLCLCPOC_00885	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HLCLCPOC_00886	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HLCLCPOC_00887	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HLCLCPOC_00888	1.27e-206	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HLCLCPOC_00889	2.11e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLCLCPOC_00890	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HLCLCPOC_00891	9.47e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HLCLCPOC_00892	2.92e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HLCLCPOC_00893	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLCLCPOC_00894	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HLCLCPOC_00895	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLCLCPOC_00896	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HLCLCPOC_00897	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLCLCPOC_00898	2.23e-261	camS	-	-	S	-	-	-	sex pheromone
HLCLCPOC_00899	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLCLCPOC_00900	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLCLCPOC_00901	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLCLCPOC_00902	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HLCLCPOC_00903	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLCLCPOC_00904	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_00905	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HLCLCPOC_00906	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_00907	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLCLCPOC_00908	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HLCLCPOC_00909	1.9e-186	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HLCLCPOC_00910	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HLCLCPOC_00911	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HLCLCPOC_00912	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HLCLCPOC_00913	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HLCLCPOC_00915	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HLCLCPOC_00916	5.73e-316	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_00917	1.12e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLCLCPOC_00919	7.62e-97	-	-	-	-	-	-	-	-
HLCLCPOC_00920	2.9e-139	-	-	-	-	-	-	-	-
HLCLCPOC_00921	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HLCLCPOC_00922	3.85e-280	pbpX	-	-	V	-	-	-	Beta-lactamase
HLCLCPOC_00923	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLCLCPOC_00924	1.01e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HLCLCPOC_00925	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLCLCPOC_00926	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLCLCPOC_00927	7.7e-43	-	-	-	E	-	-	-	Zn peptidase
HLCLCPOC_00928	1.6e-35	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLCLCPOC_00930	3.59e-69	pbpX2	-	-	V	-	-	-	Beta-lactamase
HLCLCPOC_00931	6.7e-25	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HLCLCPOC_00932	1.09e-61	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLCLCPOC_00933	1.57e-53	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HLCLCPOC_00934	3.21e-168	-	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
HLCLCPOC_00935	6.32e-68	-	-	-	G	-	-	-	Glycosyltransferase Family 4
HLCLCPOC_00936	1.46e-68	-	-	-	-	-	-	-	-
HLCLCPOC_00938	8.96e-49	-	-	-	G	-	-	-	PFAM glycoside hydrolase family 39
HLCLCPOC_00939	1.53e-187	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLCLCPOC_00940	1.37e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HLCLCPOC_00941	1.39e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLCLCPOC_00942	4.88e-200	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLCLCPOC_00943	1.05e-188	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HLCLCPOC_00944	5.99e-130	-	-	-	L	-	-	-	Integrase
HLCLCPOC_00945	2.02e-171	epsB	-	-	M	-	-	-	biosynthesis protein
HLCLCPOC_00946	7.38e-167	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HLCLCPOC_00947	1.62e-182	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HLCLCPOC_00948	1.14e-227	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HLCLCPOC_00949	8.04e-158	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HLCLCPOC_00950	6.72e-56	wcaA	-	-	M	-	-	-	Glycosyl transferase family 2
HLCLCPOC_00951	1.1e-44	-	-	-	M	-	-	-	Pfam:DUF1792
HLCLCPOC_00952	9.69e-175	-	-	-	M	-	-	-	Teichoic acid biosynthesis protein
HLCLCPOC_00953	3.06e-112	-	-	-	V	-	-	-	Glycosyl transferase, family 2
HLCLCPOC_00955	1.5e-105	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HLCLCPOC_00956	1.6e-240	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HLCLCPOC_00957	9.2e-24	cps2K	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
HLCLCPOC_00958	1.41e-169	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HLCLCPOC_00959	1.89e-228	cps3B	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HLCLCPOC_00960	6.91e-283	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HLCLCPOC_00961	6.79e-261	cps3D	-	-	-	-	-	-	-
HLCLCPOC_00962	2.92e-145	cps3E	-	-	-	-	-	-	-
HLCLCPOC_00963	1.73e-207	cps3F	-	-	-	-	-	-	-
HLCLCPOC_00964	1.03e-264	cps3H	-	-	-	-	-	-	-
HLCLCPOC_00965	5.06e-260	cps3I	-	-	G	-	-	-	Acyltransferase family
HLCLCPOC_00966	3.43e-189	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HLCLCPOC_00967	6.86e-175	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLCLCPOC_00968	0.0	-	-	-	M	-	-	-	domain protein
HLCLCPOC_00969	5.36e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLCLCPOC_00970	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HLCLCPOC_00971	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HLCLCPOC_00972	1.06e-68	-	-	-	-	-	-	-	-
HLCLCPOC_00973	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HLCLCPOC_00974	1.95e-41	-	-	-	-	-	-	-	-
HLCLCPOC_00975	1.64e-35	-	-	-	-	-	-	-	-
HLCLCPOC_00976	6.87e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HLCLCPOC_00977	1.9e-168	-	-	-	-	-	-	-	-
HLCLCPOC_00978	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HLCLCPOC_00979	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HLCLCPOC_00980	4.09e-172	lytE	-	-	M	-	-	-	NlpC/P60 family
HLCLCPOC_00981	8.01e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HLCLCPOC_00982	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HLCLCPOC_00983	2.97e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HLCLCPOC_00984	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HLCLCPOC_00985	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HLCLCPOC_00986	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HLCLCPOC_00987	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HLCLCPOC_00988	3.36e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HLCLCPOC_00989	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HLCLCPOC_00990	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HLCLCPOC_00991	0.0	-	-	-	-	-	-	-	-
HLCLCPOC_00992	1.74e-251	-	-	-	M	-	-	-	MucBP domain
HLCLCPOC_00993	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HLCLCPOC_00994	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLCLCPOC_00995	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HLCLCPOC_00996	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HLCLCPOC_00997	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLCLCPOC_00998	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLCLCPOC_00999	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLCLCPOC_01000	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLCLCPOC_01001	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HLCLCPOC_01002	2.5e-132	-	-	-	L	-	-	-	Integrase
HLCLCPOC_01003	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HLCLCPOC_01004	5.6e-41	-	-	-	-	-	-	-	-
HLCLCPOC_01005	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HLCLCPOC_01006	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLCLCPOC_01007	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HLCLCPOC_01008	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HLCLCPOC_01009	8.79e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLCLCPOC_01010	6.56e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLCLCPOC_01011	5.8e-291	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLCLCPOC_01012	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HLCLCPOC_01013	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLCLCPOC_01016	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HLCLCPOC_01028	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HLCLCPOC_01029	4.48e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HLCLCPOC_01030	1.25e-124	-	-	-	-	-	-	-	-
HLCLCPOC_01031	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLCLCPOC_01032	2.07e-200	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HLCLCPOC_01034	1.09e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLCLCPOC_01035	2.53e-240	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HLCLCPOC_01036	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HLCLCPOC_01037	7.89e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HLCLCPOC_01038	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLCLCPOC_01039	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLCLCPOC_01040	5.79e-158	-	-	-	-	-	-	-	-
HLCLCPOC_01041	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLCLCPOC_01042	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HLCLCPOC_01043	4.05e-309	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HLCLCPOC_01044	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HLCLCPOC_01045	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLCLCPOC_01046	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLCLCPOC_01047	9.32e-40	-	-	-	-	-	-	-	-
HLCLCPOC_01048	5.13e-138	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HLCLCPOC_01049	1.78e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HLCLCPOC_01050	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HLCLCPOC_01051	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HLCLCPOC_01052	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLCLCPOC_01053	9.06e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLCLCPOC_01054	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HLCLCPOC_01055	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLCLCPOC_01056	1.24e-259	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HLCLCPOC_01057	2.27e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLCLCPOC_01058	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLCLCPOC_01059	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLCLCPOC_01060	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HLCLCPOC_01061	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HLCLCPOC_01062	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLCLCPOC_01063	1.48e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HLCLCPOC_01065	1.72e-162	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HLCLCPOC_01066	7.2e-200	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_01067	6.05e-225	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HLCLCPOC_01069	9.49e-196	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLCLCPOC_01070	2.12e-84	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLCLCPOC_01071	5.48e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
HLCLCPOC_01072	1.55e-203	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HLCLCPOC_01073	3.27e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HLCLCPOC_01074	7.83e-140	-	-	-	-	-	-	-	-
HLCLCPOC_01075	6.18e-274	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HLCLCPOC_01076	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HLCLCPOC_01077	5.37e-74	-	-	-	-	-	-	-	-
HLCLCPOC_01078	4.56e-78	-	-	-	-	-	-	-	-
HLCLCPOC_01079	1.06e-146	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_01080	1.28e-110	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HLCLCPOC_01081	8.82e-119	-	-	-	-	-	-	-	-
HLCLCPOC_01082	7.12e-62	-	-	-	-	-	-	-	-
HLCLCPOC_01083	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HLCLCPOC_01086	4.29e-87	-	-	-	-	-	-	-	-
HLCLCPOC_01087	9.03e-16	-	-	-	-	-	-	-	-
HLCLCPOC_01088	3.89e-237	-	-	-	-	-	-	-	-
HLCLCPOC_01089	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HLCLCPOC_01090	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HLCLCPOC_01091	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HLCLCPOC_01092	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HLCLCPOC_01093	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HLCLCPOC_01094	5.16e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HLCLCPOC_01095	9.14e-146	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HLCLCPOC_01096	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HLCLCPOC_01097	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HLCLCPOC_01098	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HLCLCPOC_01099	2.69e-316	dinF	-	-	V	-	-	-	MatE
HLCLCPOC_01100	1.79e-42	-	-	-	-	-	-	-	-
HLCLCPOC_01103	3.48e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HLCLCPOC_01104	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HLCLCPOC_01105	4.64e-106	-	-	-	-	-	-	-	-
HLCLCPOC_01106	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HLCLCPOC_01107	6.25e-138	-	-	-	-	-	-	-	-
HLCLCPOC_01108	0.0	celR	-	-	K	-	-	-	PRD domain
HLCLCPOC_01109	2.7e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HLCLCPOC_01110	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HLCLCPOC_01111	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HLCLCPOC_01112	1.5e-310	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_01113	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLCLCPOC_01114	5.15e-252	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HLCLCPOC_01115	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HLCLCPOC_01116	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLCLCPOC_01117	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HLCLCPOC_01118	3.29e-132	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HLCLCPOC_01119	2.77e-271	arcT	-	-	E	-	-	-	Aminotransferase
HLCLCPOC_01120	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HLCLCPOC_01121	2.43e-18	-	-	-	-	-	-	-	-
HLCLCPOC_01122	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HLCLCPOC_01123	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HLCLCPOC_01124	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HLCLCPOC_01125	0.0	yhaN	-	-	L	-	-	-	AAA domain
HLCLCPOC_01126	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLCLCPOC_01127	7.82e-278	-	-	-	-	-	-	-	-
HLCLCPOC_01128	1.39e-232	-	-	-	M	-	-	-	Peptidase family S41
HLCLCPOC_01129	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HLCLCPOC_01130	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HLCLCPOC_01131	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HLCLCPOC_01132	3e-127	-	-	-	-	-	-	-	-
HLCLCPOC_01133	3.36e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HLCLCPOC_01134	5.27e-203	-	-	-	T	-	-	-	Histidine kinase
HLCLCPOC_01135	1.73e-134	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HLCLCPOC_01136	1.13e-78	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
HLCLCPOC_01137	2.26e-167	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HLCLCPOC_01138	1.18e-100	-	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HLCLCPOC_01139	3.3e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HLCLCPOC_01140	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLCLCPOC_01141	5.72e-90	-	-	-	S	-	-	-	NUDIX domain
HLCLCPOC_01142	0.0	-	-	-	S	-	-	-	membrane
HLCLCPOC_01143	1.22e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLCLCPOC_01144	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HLCLCPOC_01145	5.12e-285	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HLCLCPOC_01146	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HLCLCPOC_01147	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HLCLCPOC_01148	3.39e-138	-	-	-	-	-	-	-	-
HLCLCPOC_01149	2.71e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HLCLCPOC_01150	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_01151	3e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HLCLCPOC_01152	0.0	-	-	-	-	-	-	-	-
HLCLCPOC_01153	4.75e-80	-	-	-	-	-	-	-	-
HLCLCPOC_01154	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
HLCLCPOC_01155	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HLCLCPOC_01156	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HLCLCPOC_01157	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLCLCPOC_01158	7.9e-72	-	-	-	-	-	-	-	-
HLCLCPOC_01159	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HLCLCPOC_01160	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_01161	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_01162	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HLCLCPOC_01163	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLCLCPOC_01164	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLCLCPOC_01165	1.45e-145	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLCLCPOC_01166	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HLCLCPOC_01167	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HLCLCPOC_01168	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HLCLCPOC_01169	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HLCLCPOC_01170	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HLCLCPOC_01171	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HLCLCPOC_01172	4.28e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HLCLCPOC_01173	1.11e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLCLCPOC_01174	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HLCLCPOC_01175	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HLCLCPOC_01176	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HLCLCPOC_01177	8.54e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HLCLCPOC_01178	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HLCLCPOC_01179	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLCLCPOC_01180	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLCLCPOC_01181	9.54e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLCLCPOC_01182	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLCLCPOC_01183	4.73e-315	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HLCLCPOC_01184	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HLCLCPOC_01185	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLCLCPOC_01186	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLCLCPOC_01187	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HLCLCPOC_01188	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLCLCPOC_01189	4.59e-73	-	-	-	-	-	-	-	-
HLCLCPOC_01190	4.06e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HLCLCPOC_01191	7.09e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HLCLCPOC_01192	1.35e-82	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLCLCPOC_01193	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HLCLCPOC_01194	1.9e-315	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HLCLCPOC_01195	6.32e-114	-	-	-	-	-	-	-	-
HLCLCPOC_01196	3.3e-126	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HLCLCPOC_01197	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HLCLCPOC_01198	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HLCLCPOC_01199	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLCLCPOC_01200	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HLCLCPOC_01201	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLCLCPOC_01202	1.91e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HLCLCPOC_01203	1.09e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HLCLCPOC_01204	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HLCLCPOC_01205	9.55e-55	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLCLCPOC_01206	3.21e-52	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLCLCPOC_01207	1.13e-225	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLCLCPOC_01208	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLCLCPOC_01209	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HLCLCPOC_01210	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HLCLCPOC_01211	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLCLCPOC_01212	1.59e-217	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HLCLCPOC_01213	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HLCLCPOC_01214	2.36e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLCLCPOC_01215	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
HLCLCPOC_01216	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLCLCPOC_01217	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HLCLCPOC_01218	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLCLCPOC_01219	3.46e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLCLCPOC_01220	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLCLCPOC_01221	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLCLCPOC_01222	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLCLCPOC_01223	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HLCLCPOC_01224	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HLCLCPOC_01225	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLCLCPOC_01226	9.3e-144	-	-	-	S	-	-	-	membrane
HLCLCPOC_01227	2.33e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLCLCPOC_01228	8.38e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HLCLCPOC_01229	0.0	-	-	-	S	-	-	-	membrane
HLCLCPOC_01230	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLCLCPOC_01231	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLCLCPOC_01232	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLCLCPOC_01233	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HLCLCPOC_01234	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HLCLCPOC_01235	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HLCLCPOC_01236	1.56e-139	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HLCLCPOC_01237	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HLCLCPOC_01238	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HLCLCPOC_01239	2.23e-178	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HLCLCPOC_01240	2.29e-225	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLCLCPOC_01241	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HLCLCPOC_01242	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HLCLCPOC_01243	1.77e-205	-	-	-	-	-	-	-	-
HLCLCPOC_01244	1.34e-232	-	-	-	-	-	-	-	-
HLCLCPOC_01245	3.55e-127	-	-	-	S	-	-	-	Protein conserved in bacteria
HLCLCPOC_01246	3.11e-73	-	-	-	-	-	-	-	-
HLCLCPOC_01247	2.97e-41	-	-	-	-	-	-	-	-
HLCLCPOC_01251	9.81e-27	-	-	-	-	-	-	-	-
HLCLCPOC_01252	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_01253	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HLCLCPOC_01254	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HLCLCPOC_01255	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HLCLCPOC_01256	1.41e-244	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HLCLCPOC_01257	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLCLCPOC_01258	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HLCLCPOC_01259	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLCLCPOC_01260	1.38e-193	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLCLCPOC_01261	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLCLCPOC_01262	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLCLCPOC_01263	3.62e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLCLCPOC_01264	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HLCLCPOC_01265	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HLCLCPOC_01266	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HLCLCPOC_01267	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_01268	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLCLCPOC_01269	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLCLCPOC_01270	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLCLCPOC_01271	1.19e-73	-	-	-	-	-	-	-	-
HLCLCPOC_01272	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HLCLCPOC_01273	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLCLCPOC_01274	1.68e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLCLCPOC_01275	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLCLCPOC_01276	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLCLCPOC_01277	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLCLCPOC_01278	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HLCLCPOC_01279	7.83e-60	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HLCLCPOC_01280	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HLCLCPOC_01281	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLCLCPOC_01282	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HLCLCPOC_01283	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HLCLCPOC_01284	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HLCLCPOC_01285	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HLCLCPOC_01286	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HLCLCPOC_01287	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLCLCPOC_01288	3.09e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLCLCPOC_01289	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLCLCPOC_01290	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLCLCPOC_01291	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HLCLCPOC_01292	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLCLCPOC_01293	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLCLCPOC_01294	9.38e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLCLCPOC_01295	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HLCLCPOC_01296	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HLCLCPOC_01297	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLCLCPOC_01298	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HLCLCPOC_01299	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLCLCPOC_01300	3.2e-70	-	-	-	-	-	-	-	-
HLCLCPOC_01301	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLCLCPOC_01302	9.06e-112	-	-	-	-	-	-	-	-
HLCLCPOC_01303	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HLCLCPOC_01304	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HLCLCPOC_01306	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HLCLCPOC_01307	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HLCLCPOC_01308	7.03e-225	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HLCLCPOC_01309	8.61e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HLCLCPOC_01310	2.92e-138	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HLCLCPOC_01311	7.29e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HLCLCPOC_01312	2.79e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HLCLCPOC_01313	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HLCLCPOC_01314	3.53e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HLCLCPOC_01315	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HLCLCPOC_01316	4.84e-278	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HLCLCPOC_01317	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HLCLCPOC_01318	8.04e-254	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HLCLCPOC_01319	1.09e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HLCLCPOC_01320	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLCLCPOC_01321	1.33e-228	yneE	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_01322	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLCLCPOC_01323	9.77e-231	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLCLCPOC_01324	1.06e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLCLCPOC_01325	8.89e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HLCLCPOC_01326	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HLCLCPOC_01327	5.38e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLCLCPOC_01328	5.25e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLCLCPOC_01329	7.23e-93	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HLCLCPOC_01330	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HLCLCPOC_01331	6.17e-201	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLCLCPOC_01332	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HLCLCPOC_01333	3.13e-173	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HLCLCPOC_01334	1.01e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HLCLCPOC_01335	2.1e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HLCLCPOC_01336	1.46e-204	-	-	-	K	-	-	-	LysR substrate binding domain
HLCLCPOC_01337	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HLCLCPOC_01338	1.54e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLCLCPOC_01339	1.49e-121	-	-	-	K	-	-	-	transcriptional regulator
HLCLCPOC_01340	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HLCLCPOC_01341	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HLCLCPOC_01342	3.35e-111	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HLCLCPOC_01343	2.19e-07	-	-	-	K	-	-	-	transcriptional regulator
HLCLCPOC_01344	1.48e-71	-	-	-	-	-	-	-	-
HLCLCPOC_01345	2.02e-39	-	-	-	-	-	-	-	-
HLCLCPOC_01346	1.69e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HLCLCPOC_01347	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HLCLCPOC_01348	3.16e-64	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HLCLCPOC_01349	2.05e-55	-	-	-	-	-	-	-	-
HLCLCPOC_01350	4.98e-107	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HLCLCPOC_01351	3.05e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLCLCPOC_01352	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HLCLCPOC_01353	1.79e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HLCLCPOC_01354	1.51e-48	-	-	-	-	-	-	-	-
HLCLCPOC_01355	5.79e-21	-	-	-	-	-	-	-	-
HLCLCPOC_01356	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HLCLCPOC_01357	4e-40	-	-	-	S	-	-	-	CsbD-like
HLCLCPOC_01358	1.06e-53	-	-	-	-	-	-	-	-
HLCLCPOC_01359	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLCLCPOC_01360	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HLCLCPOC_01361	2.42e-280	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLCLCPOC_01362	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HLCLCPOC_01363	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HLCLCPOC_01364	1.52e-67	-	-	-	-	-	-	-	-
HLCLCPOC_01365	6.53e-58	-	-	-	-	-	-	-	-
HLCLCPOC_01366	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLCLCPOC_01367	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HLCLCPOC_01368	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HLCLCPOC_01369	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HLCLCPOC_01370	1.03e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HLCLCPOC_01371	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HLCLCPOC_01372	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HLCLCPOC_01373	9.62e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HLCLCPOC_01374	4.98e-250	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLCLCPOC_01375	1.03e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HLCLCPOC_01376	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HLCLCPOC_01377	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HLCLCPOC_01378	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HLCLCPOC_01379	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HLCLCPOC_01380	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HLCLCPOC_01381	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HLCLCPOC_01382	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HLCLCPOC_01384	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLCLCPOC_01385	1.41e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLCLCPOC_01386	3.19e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HLCLCPOC_01387	7.56e-109	-	-	-	T	-	-	-	Universal stress protein family
HLCLCPOC_01388	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLCLCPOC_01389	1.34e-232	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLCLCPOC_01390	8.03e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLCLCPOC_01391	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HLCLCPOC_01392	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLCLCPOC_01393	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HLCLCPOC_01394	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLCLCPOC_01396	4.11e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HLCLCPOC_01397	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLCLCPOC_01398	3.65e-308	-	-	-	P	-	-	-	Major Facilitator Superfamily
HLCLCPOC_01399	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HLCLCPOC_01400	2.26e-95	-	-	-	S	-	-	-	SnoaL-like domain
HLCLCPOC_01401	9.18e-254	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HLCLCPOC_01402	3.32e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HLCLCPOC_01403	1.64e-62	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLCLCPOC_01404	1.75e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HLCLCPOC_01405	1.44e-234	-	-	-	V	-	-	-	LD-carboxypeptidase
HLCLCPOC_01406	8.41e-97	XK27_05710	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLCLCPOC_01407	5.46e-157	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HLCLCPOC_01408	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLCLCPOC_01409	1.86e-246	-	-	-	-	-	-	-	-
HLCLCPOC_01410	6.59e-28	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HLCLCPOC_01411	1.99e-132	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HLCLCPOC_01412	8.53e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HLCLCPOC_01413	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HLCLCPOC_01414	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HLCLCPOC_01415	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HLCLCPOC_01416	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLCLCPOC_01417	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLCLCPOC_01418	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLCLCPOC_01419	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HLCLCPOC_01420	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HLCLCPOC_01421	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HLCLCPOC_01422	6.38e-92	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HLCLCPOC_01425	7.13e-112	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HLCLCPOC_01426	9.52e-25	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HLCLCPOC_01427	8.49e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HLCLCPOC_01428	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HLCLCPOC_01430	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
HLCLCPOC_01431	5.3e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_01432	9.28e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLCLCPOC_01433	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HLCLCPOC_01434	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_01435	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HLCLCPOC_01436	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HLCLCPOC_01437	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HLCLCPOC_01438	3.15e-29	-	-	-	-	-	-	-	-
HLCLCPOC_01439	1.23e-63	-	-	-	-	-	-	-	-
HLCLCPOC_01440	6.64e-189	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HLCLCPOC_01441	7.81e-264	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLCLCPOC_01443	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HLCLCPOC_01444	8.55e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HLCLCPOC_01445	2.13e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HLCLCPOC_01446	7.13e-311	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HLCLCPOC_01447	1.09e-178	-	-	-	-	-	-	-	-
HLCLCPOC_01448	4.51e-77	-	-	-	-	-	-	-	-
HLCLCPOC_01449	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HLCLCPOC_01450	9.59e-290	-	-	-	-	-	-	-	-
HLCLCPOC_01451	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HLCLCPOC_01452	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HLCLCPOC_01453	8.63e-275	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLCLCPOC_01454	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLCLCPOC_01455	4.87e-123	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HLCLCPOC_01456	1.73e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLCLCPOC_01457	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HLCLCPOC_01458	1.86e-86	-	-	-	-	-	-	-	-
HLCLCPOC_01459	1.83e-314	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HLCLCPOC_01460	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLCLCPOC_01461	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HLCLCPOC_01462	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HLCLCPOC_01463	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLCLCPOC_01464	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HLCLCPOC_01465	1.59e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HLCLCPOC_01466	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_01467	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLCLCPOC_01468	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLCLCPOC_01469	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLCLCPOC_01470	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HLCLCPOC_01471	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HLCLCPOC_01472	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HLCLCPOC_01473	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HLCLCPOC_01474	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HLCLCPOC_01475	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLCLCPOC_01476	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HLCLCPOC_01477	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLCLCPOC_01478	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLCLCPOC_01480	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HLCLCPOC_01481	7.05e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HLCLCPOC_01482	1.5e-161	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HLCLCPOC_01483	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HLCLCPOC_01484	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HLCLCPOC_01485	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HLCLCPOC_01486	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HLCLCPOC_01487	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HLCLCPOC_01488	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLCLCPOC_01489	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HLCLCPOC_01490	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLCLCPOC_01491	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLCLCPOC_01492	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_01493	6.46e-109	-	-	-	-	-	-	-	-
HLCLCPOC_01494	4.96e-289	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLCLCPOC_01495	5.66e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLCLCPOC_01496	9.1e-193	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HLCLCPOC_01497	7.1e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HLCLCPOC_01498	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLCLCPOC_01499	2.06e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HLCLCPOC_01500	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HLCLCPOC_01501	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HLCLCPOC_01502	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HLCLCPOC_01503	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HLCLCPOC_01504	5.15e-247	-	-	-	S	-	-	-	Helix-turn-helix domain
HLCLCPOC_01505	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLCLCPOC_01506	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLCLCPOC_01507	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLCLCPOC_01508	1.18e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLCLCPOC_01509	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLCLCPOC_01510	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HLCLCPOC_01511	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HLCLCPOC_01512	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HLCLCPOC_01513	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HLCLCPOC_01514	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HLCLCPOC_01515	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HLCLCPOC_01516	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HLCLCPOC_01518	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLCLCPOC_01519	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HLCLCPOC_01520	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLCLCPOC_01521	1.96e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HLCLCPOC_01522	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HLCLCPOC_01523	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HLCLCPOC_01524	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_01525	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLCLCPOC_01526	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HLCLCPOC_01527	2.65e-81	-	-	-	P	-	-	-	Rhodanese Homology Domain
HLCLCPOC_01528	1.75e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLCLCPOC_01529	3.34e-267	-	-	-	-	-	-	-	-
HLCLCPOC_01530	1.49e-281	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HLCLCPOC_01531	8.65e-221	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HLCLCPOC_01532	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HLCLCPOC_01533	1.05e-89	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HLCLCPOC_01534	3.49e-307	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLCLCPOC_01535	9.28e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HLCLCPOC_01536	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_01537	6.03e-270	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HLCLCPOC_01538	1.23e-230	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HLCLCPOC_01539	3.35e-148	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HLCLCPOC_01540	5.87e-177	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HLCLCPOC_01541	9.89e-138	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HLCLCPOC_01542	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HLCLCPOC_01543	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HLCLCPOC_01544	5.7e-146	-	-	-	GM	-	-	-	epimerase
HLCLCPOC_01545	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HLCLCPOC_01546	6.13e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_01547	1.86e-272	-	-	-	S	-	-	-	membrane
HLCLCPOC_01548	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
HLCLCPOC_01549	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLCLCPOC_01550	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_01551	3.72e-147	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HLCLCPOC_01552	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HLCLCPOC_01553	2.13e-168	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HLCLCPOC_01554	1.52e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
HLCLCPOC_01555	4.15e-145	-	-	-	GM	-	-	-	NmrA-like family
HLCLCPOC_01556	8.62e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HLCLCPOC_01557	3.86e-205	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_01558	9.29e-222	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HLCLCPOC_01560	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HLCLCPOC_01561	1.11e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HLCLCPOC_01562	4.7e-262	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLCLCPOC_01563	8.22e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HLCLCPOC_01564	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_01566	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HLCLCPOC_01567	5.9e-103	-	-	-	K	-	-	-	MarR family
HLCLCPOC_01568	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HLCLCPOC_01569	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HLCLCPOC_01570	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_01571	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLCLCPOC_01572	2.03e-251	-	-	-	-	-	-	-	-
HLCLCPOC_01573	2.59e-256	-	-	-	-	-	-	-	-
HLCLCPOC_01574	2.45e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_01575	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HLCLCPOC_01576	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLCLCPOC_01577	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLCLCPOC_01578	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HLCLCPOC_01579	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HLCLCPOC_01580	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HLCLCPOC_01581	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLCLCPOC_01582	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HLCLCPOC_01583	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLCLCPOC_01584	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HLCLCPOC_01585	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HLCLCPOC_01586	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HLCLCPOC_01587	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HLCLCPOC_01588	3.65e-166	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLCLCPOC_01589	7.36e-220	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HLCLCPOC_01590	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLCLCPOC_01591	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLCLCPOC_01592	2.15e-131	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLCLCPOC_01593	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HLCLCPOC_01594	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HLCLCPOC_01595	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HLCLCPOC_01596	3.23e-214	-	-	-	G	-	-	-	Fructosamine kinase
HLCLCPOC_01597	1.35e-147	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HLCLCPOC_01598	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLCLCPOC_01599	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLCLCPOC_01600	2.56e-76	-	-	-	-	-	-	-	-
HLCLCPOC_01601	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLCLCPOC_01602	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HLCLCPOC_01603	1.11e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HLCLCPOC_01604	4.78e-65	-	-	-	-	-	-	-	-
HLCLCPOC_01605	1.17e-65	-	-	-	-	-	-	-	-
HLCLCPOC_01606	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLCLCPOC_01607	1.38e-311	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLCLCPOC_01608	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLCLCPOC_01609	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HLCLCPOC_01610	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLCLCPOC_01611	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HLCLCPOC_01612	3.46e-265	pbpX2	-	-	V	-	-	-	Beta-lactamase
HLCLCPOC_01613	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLCLCPOC_01614	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HLCLCPOC_01615	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLCLCPOC_01616	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLCLCPOC_01617	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HLCLCPOC_01618	1.53e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HLCLCPOC_01619	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLCLCPOC_01620	9.8e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HLCLCPOC_01621	2.44e-245	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HLCLCPOC_01622	1.92e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HLCLCPOC_01623	1.63e-121	-	-	-	-	-	-	-	-
HLCLCPOC_01624	9.01e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HLCLCPOC_01625	0.0	-	-	-	G	-	-	-	Major Facilitator
HLCLCPOC_01626	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLCLCPOC_01627	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLCLCPOC_01628	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HLCLCPOC_01629	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HLCLCPOC_01630	2.58e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HLCLCPOC_01631	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HLCLCPOC_01632	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLCLCPOC_01633	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLCLCPOC_01634	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HLCLCPOC_01635	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HLCLCPOC_01636	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLCLCPOC_01637	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLCLCPOC_01638	8.63e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HLCLCPOC_01639	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLCLCPOC_01640	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HLCLCPOC_01641	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HLCLCPOC_01642	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLCLCPOC_01643	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HLCLCPOC_01644	3.4e-177	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HLCLCPOC_01645	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HLCLCPOC_01646	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HLCLCPOC_01647	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HLCLCPOC_01648	1.16e-28	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLCLCPOC_01649	2.16e-55	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLCLCPOC_01650	7.8e-123	-	-	-	-	-	-	-	-
HLCLCPOC_01651	6.35e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HLCLCPOC_01652	1.01e-100	-	-	-	-	-	-	-	-
HLCLCPOC_01653	3.81e-87	-	-	-	-	-	-	-	-
HLCLCPOC_01654	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HLCLCPOC_01655	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HLCLCPOC_01656	1.89e-282	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HLCLCPOC_01657	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLCLCPOC_01658	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLCLCPOC_01659	2.38e-294	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HLCLCPOC_01662	3.19e-50	-	-	-	S	-	-	-	Haemolysin XhlA
HLCLCPOC_01663	2.94e-260	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HLCLCPOC_01664	6.08e-73	-	-	-	-	-	-	-	-
HLCLCPOC_01667	2.27e-229	-	-	-	-	-	-	-	-
HLCLCPOC_01668	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HLCLCPOC_01669	0.0	-	-	-	S	-	-	-	Phage tail protein
HLCLCPOC_01670	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HLCLCPOC_01671	5.58e-06	-	-	-	-	-	-	-	-
HLCLCPOC_01673	1.73e-89	-	-	-	S	-	-	-	Phage tail tube protein
HLCLCPOC_01674	1.25e-33	-	-	-	-	-	-	-	-
HLCLCPOC_01675	2.3e-51	-	-	-	-	-	-	-	-
HLCLCPOC_01676	1.21e-32	-	-	-	S	-	-	-	Phage head-tail joining protein
HLCLCPOC_01677	5.37e-74	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HLCLCPOC_01678	4.52e-266	-	-	-	S	-	-	-	Phage capsid family
HLCLCPOC_01679	7.98e-163	-	-	-	S	-	-	-	Clp protease
HLCLCPOC_01680	1.57e-262	-	-	-	S	-	-	-	Phage portal protein
HLCLCPOC_01681	1.26e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HLCLCPOC_01682	2.28e-220	-	-	-	S	-	-	-	Phage Terminase
HLCLCPOC_01683	6.62e-59	-	-	-	L	-	-	-	Phage terminase, small subunit
HLCLCPOC_01684	6.69e-114	-	-	-	L	-	-	-	HNH nucleases
HLCLCPOC_01685	1.83e-21	-	-	-	-	-	-	-	-
HLCLCPOC_01687	2.71e-85	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HLCLCPOC_01688	5.53e-116	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HLCLCPOC_01689	1.75e-21	-	-	-	-	-	-	-	-
HLCLCPOC_01692	2.48e-58	-	-	-	-	-	-	-	-
HLCLCPOC_01694	1.19e-186	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HLCLCPOC_01695	1.53e-78	-	-	-	L	-	-	-	DnaD domain protein
HLCLCPOC_01701	1.38e-07	-	-	-	-	-	-	-	-
HLCLCPOC_01704	3.89e-82	-	-	-	S	-	-	-	DNA binding
HLCLCPOC_01705	1.67e-16	-	-	-	-	-	-	-	-
HLCLCPOC_01706	3.05e-107	-	-	-	K	-	-	-	Peptidase S24-like
HLCLCPOC_01713	9.66e-74	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLCLCPOC_01714	1.75e-43	-	-	-	-	-	-	-	-
HLCLCPOC_01715	4.15e-183	-	-	-	Q	-	-	-	Methyltransferase
HLCLCPOC_01716	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HLCLCPOC_01717	5.79e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HLCLCPOC_01718	4.57e-135	-	-	-	K	-	-	-	Helix-turn-helix domain
HLCLCPOC_01719	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLCLCPOC_01720	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HLCLCPOC_01721	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HLCLCPOC_01722	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLCLCPOC_01723	2.05e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLCLCPOC_01724	6.62e-62	-	-	-	-	-	-	-	-
HLCLCPOC_01725	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLCLCPOC_01726	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HLCLCPOC_01727	7.34e-219	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HLCLCPOC_01728	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HLCLCPOC_01729	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HLCLCPOC_01730	0.0	cps4J	-	-	S	-	-	-	MatE
HLCLCPOC_01731	1.61e-226	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HLCLCPOC_01732	2.9e-292	-	-	-	-	-	-	-	-
HLCLCPOC_01733	4.8e-229	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HLCLCPOC_01734	2.65e-248	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HLCLCPOC_01735	3.31e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HLCLCPOC_01736	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HLCLCPOC_01737	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HLCLCPOC_01738	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HLCLCPOC_01739	8.82e-164	epsB	-	-	M	-	-	-	biosynthesis protein
HLCLCPOC_01740	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLCLCPOC_01741	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_01742	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HLCLCPOC_01743	5.12e-31	-	-	-	-	-	-	-	-
HLCLCPOC_01744	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HLCLCPOC_01745	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HLCLCPOC_01746	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HLCLCPOC_01747	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLCLCPOC_01748	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLCLCPOC_01749	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLCLCPOC_01750	9.34e-201	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLCLCPOC_01751	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLCLCPOC_01752	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLCLCPOC_01753	2.22e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLCLCPOC_01754	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLCLCPOC_01755	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HLCLCPOC_01756	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HLCLCPOC_01757	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HLCLCPOC_01758	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HLCLCPOC_01759	3.16e-156	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HLCLCPOC_01760	3.01e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HLCLCPOC_01761	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLCLCPOC_01762	4.98e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HLCLCPOC_01763	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HLCLCPOC_01764	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HLCLCPOC_01765	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HLCLCPOC_01766	0.0	-	-	-	-	-	-	-	-
HLCLCPOC_01767	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HLCLCPOC_01768	2.12e-80	-	-	-	-	-	-	-	-
HLCLCPOC_01769	1.07e-37	-	-	-	-	-	-	-	-
HLCLCPOC_01770	7.38e-256	-	-	-	-	-	-	-	-
HLCLCPOC_01771	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HLCLCPOC_01772	4.1e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HLCLCPOC_01773	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HLCLCPOC_01774	1.02e-207	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HLCLCPOC_01775	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HLCLCPOC_01776	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLCLCPOC_01777	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HLCLCPOC_01778	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HLCLCPOC_01779	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLCLCPOC_01780	6.45e-111	-	-	-	-	-	-	-	-
HLCLCPOC_01781	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HLCLCPOC_01782	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLCLCPOC_01783	5.96e-241	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HLCLCPOC_01784	2.16e-39	-	-	-	-	-	-	-	-
HLCLCPOC_01785	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HLCLCPOC_01786	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLCLCPOC_01787	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLCLCPOC_01788	1.02e-155	-	-	-	S	-	-	-	repeat protein
HLCLCPOC_01789	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HLCLCPOC_01790	0.0	-	-	-	N	-	-	-	domain, Protein
HLCLCPOC_01791	1.22e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HLCLCPOC_01792	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HLCLCPOC_01793	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HLCLCPOC_01794	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HLCLCPOC_01795	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLCLCPOC_01796	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HLCLCPOC_01797	3.69e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HLCLCPOC_01798	1.68e-157	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLCLCPOC_01799	7.74e-47	-	-	-	-	-	-	-	-
HLCLCPOC_01800	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HLCLCPOC_01801	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLCLCPOC_01802	2.05e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HLCLCPOC_01803	2.57e-47	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLCLCPOC_01804	7.33e-101	-	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HLCLCPOC_01805	5.47e-95	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HLCLCPOC_01806	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLCLCPOC_01807	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HLCLCPOC_01808	1.19e-186	ylmH	-	-	S	-	-	-	S4 domain protein
HLCLCPOC_01809	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HLCLCPOC_01810	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLCLCPOC_01811	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLCLCPOC_01812	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLCLCPOC_01813	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLCLCPOC_01814	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLCLCPOC_01815	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLCLCPOC_01816	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLCLCPOC_01817	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLCLCPOC_01818	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HLCLCPOC_01819	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLCLCPOC_01820	1.35e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HLCLCPOC_01821	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HLCLCPOC_01822	4.99e-224	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HLCLCPOC_01823	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HLCLCPOC_01824	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLCLCPOC_01825	3.55e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HLCLCPOC_01826	2.17e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLCLCPOC_01828	6.46e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HLCLCPOC_01829	3.97e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLCLCPOC_01830	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HLCLCPOC_01831	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HLCLCPOC_01832	5.57e-247	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HLCLCPOC_01833	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HLCLCPOC_01834	1.27e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLCLCPOC_01835	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLCLCPOC_01836	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HLCLCPOC_01837	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HLCLCPOC_01838	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HLCLCPOC_01839	2.62e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HLCLCPOC_01840	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLCLCPOC_01841	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLCLCPOC_01842	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HLCLCPOC_01843	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HLCLCPOC_01865	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HLCLCPOC_01866	5.28e-83	-	-	-	-	-	-	-	-
HLCLCPOC_01867	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HLCLCPOC_01868	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLCLCPOC_01869	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HLCLCPOC_01870	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HLCLCPOC_01871	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLCLCPOC_01872	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HLCLCPOC_01873	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLCLCPOC_01874	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLCLCPOC_01875	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HLCLCPOC_01876	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLCLCPOC_01877	3.84e-237	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HLCLCPOC_01879	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HLCLCPOC_01880	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HLCLCPOC_01881	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HLCLCPOC_01882	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HLCLCPOC_01883	2.52e-241	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HLCLCPOC_01884	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HLCLCPOC_01885	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLCLCPOC_01886	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HLCLCPOC_01887	8.49e-66	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HLCLCPOC_01888	5.32e-209	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HLCLCPOC_01889	4.47e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HLCLCPOC_01890	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HLCLCPOC_01891	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLCLCPOC_01892	1.6e-96	-	-	-	-	-	-	-	-
HLCLCPOC_01893	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLCLCPOC_01894	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HLCLCPOC_01895	2.74e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLCLCPOC_01896	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLCLCPOC_01897	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HLCLCPOC_01898	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HLCLCPOC_01899	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLCLCPOC_01900	8.74e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HLCLCPOC_01901	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HLCLCPOC_01902	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HLCLCPOC_01903	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLCLCPOC_01904	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HLCLCPOC_01905	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HLCLCPOC_01906	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLCLCPOC_01907	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HLCLCPOC_01908	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLCLCPOC_01909	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLCLCPOC_01910	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HLCLCPOC_01911	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLCLCPOC_01912	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HLCLCPOC_01913	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLCLCPOC_01914	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HLCLCPOC_01915	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLCLCPOC_01916	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLCLCPOC_01917	2.07e-116	-	-	-	-	-	-	-	-
HLCLCPOC_01918	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HLCLCPOC_01919	1.35e-93	-	-	-	-	-	-	-	-
HLCLCPOC_01920	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLCLCPOC_01921	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLCLCPOC_01922	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HLCLCPOC_01923	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HLCLCPOC_01924	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLCLCPOC_01925	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HLCLCPOC_01926	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLCLCPOC_01927	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HLCLCPOC_01928	3.84e-316	ymfH	-	-	S	-	-	-	Peptidase M16
HLCLCPOC_01929	8.72e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HLCLCPOC_01930	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HLCLCPOC_01931	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLCLCPOC_01932	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HLCLCPOC_01933	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_01934	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HLCLCPOC_01935	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HLCLCPOC_01936	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HLCLCPOC_01937	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HLCLCPOC_01938	6.23e-183	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HLCLCPOC_01939	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HLCLCPOC_01940	4.7e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HLCLCPOC_01941	9.36e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HLCLCPOC_01942	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLCLCPOC_01943	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLCLCPOC_01944	3.3e-301	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HLCLCPOC_01945	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLCLCPOC_01946	2.22e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HLCLCPOC_01947	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLCLCPOC_01948	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HLCLCPOC_01949	1.07e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLCLCPOC_01950	1.15e-144	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HLCLCPOC_01951	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HLCLCPOC_01952	6.4e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HLCLCPOC_01953	2.63e-58	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLCLCPOC_01954	7.24e-291	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HLCLCPOC_01955	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HLCLCPOC_01956	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
HLCLCPOC_01957	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HLCLCPOC_01958	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HLCLCPOC_01959	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
HLCLCPOC_01960	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HLCLCPOC_01961	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HLCLCPOC_01962	1.34e-52	-	-	-	-	-	-	-	-
HLCLCPOC_01963	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HLCLCPOC_01964	8.1e-261	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HLCLCPOC_01965	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLCLCPOC_01966	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HLCLCPOC_01967	3.78e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HLCLCPOC_01968	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HLCLCPOC_01969	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HLCLCPOC_01970	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HLCLCPOC_01971	1.23e-190	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HLCLCPOC_01972	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLCLCPOC_01973	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLCLCPOC_01974	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HLCLCPOC_01975	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HLCLCPOC_01976	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HLCLCPOC_01977	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HLCLCPOC_01978	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HLCLCPOC_01979	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HLCLCPOC_01980	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLCLCPOC_01981	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HLCLCPOC_01982	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLCLCPOC_01983	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLCLCPOC_01984	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLCLCPOC_01985	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLCLCPOC_01986	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLCLCPOC_01987	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLCLCPOC_01988	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HLCLCPOC_01989	1.44e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HLCLCPOC_01990	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLCLCPOC_01991	1.24e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLCLCPOC_01992	1.79e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLCLCPOC_01993	1.99e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLCLCPOC_01994	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLCLCPOC_01995	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HLCLCPOC_01996	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HLCLCPOC_01997	2.5e-173	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HLCLCPOC_01998	2.36e-248	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HLCLCPOC_01999	2.65e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HLCLCPOC_02000	2.1e-41	-	-	-	-	-	-	-	-
HLCLCPOC_02001	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HLCLCPOC_02002	1.33e-77	-	-	-	-	-	-	-	-
HLCLCPOC_02003	5.54e-180	-	-	-	-	-	-	-	-
HLCLCPOC_02004	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HLCLCPOC_02005	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02006	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HLCLCPOC_02007	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HLCLCPOC_02009	1.59e-79	-	-	-	K	-	-	-	IrrE N-terminal-like domain
HLCLCPOC_02011	3.72e-58	-	-	-	S	-	-	-	Bacteriophage holin
HLCLCPOC_02012	7.86e-65	-	-	-	-	-	-	-	-
HLCLCPOC_02013	4.78e-222	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HLCLCPOC_02015	5.92e-104	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLCLCPOC_02018	1.05e-215	-	-	-	M	-	-	-	Prophage endopeptidase tail
HLCLCPOC_02019	4.16e-176	-	-	-	S	-	-	-	Phage tail protein
HLCLCPOC_02021	2e-311	-	-	-	D	-	-	-	domain protein
HLCLCPOC_02023	5.4e-92	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
HLCLCPOC_02024	3.54e-125	-	-	-	-	-	-	-	-
HLCLCPOC_02025	2.39e-61	-	-	-	-	-	-	-	-
HLCLCPOC_02026	2.66e-82	-	-	-	-	-	-	-	-
HLCLCPOC_02027	2.78e-51	-	-	-	-	-	-	-	-
HLCLCPOC_02028	5.75e-67	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HLCLCPOC_02029	7.32e-221	-	-	-	S	-	-	-	Phage major capsid protein E
HLCLCPOC_02030	1.35e-57	-	-	-	-	-	-	-	-
HLCLCPOC_02031	8.28e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HLCLCPOC_02032	2.82e-165	-	-	-	S	-	-	-	Phage Mu protein F like protein
HLCLCPOC_02033	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HLCLCPOC_02034	5.13e-167	-	-	-	S	-	-	-	Terminase-like family
HLCLCPOC_02035	9.61e-85	-	-	-	S	-	-	-	Terminase small subunit
HLCLCPOC_02036	7.99e-29	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLCLCPOC_02038	3e-39	-	-	-	-	-	-	-	-
HLCLCPOC_02039	1.38e-25	-	-	-	-	-	-	-	-
HLCLCPOC_02040	1.31e-11	-	-	-	-	-	-	-	-
HLCLCPOC_02041	1.96e-99	-	-	-	-	-	-	-	-
HLCLCPOC_02044	1.24e-105	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HLCLCPOC_02045	4.26e-07	-	-	-	-	-	-	-	-
HLCLCPOC_02046	3.3e-86	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HLCLCPOC_02047	5.51e-82	-	-	-	-	-	-	-	-
HLCLCPOC_02048	5.23e-77	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
HLCLCPOC_02050	2.49e-193	-	-	-	S	-	-	-	IstB-like ATP binding protein
HLCLCPOC_02051	2.18e-38	-	-	-	L	-	-	-	DnaD domain protein
HLCLCPOC_02052	6.58e-174	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
HLCLCPOC_02053	2.09e-189	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HLCLCPOC_02054	1.56e-94	-	-	-	-	-	-	-	-
HLCLCPOC_02056	8.32e-24	-	-	-	-	-	-	-	-
HLCLCPOC_02058	1.3e-111	-	-	-	-	-	-	-	-
HLCLCPOC_02059	6.59e-72	-	-	-	-	-	-	-	-
HLCLCPOC_02062	1.19e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HLCLCPOC_02067	4.23e-08	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLCLCPOC_02068	8.82e-24	-	-	-	K	ko:K22299	-	ko00000,ko03000	sequence-specific DNA binding
HLCLCPOC_02069	6.17e-08	-	-	-	K	ko:K22299	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HLCLCPOC_02071	1.57e-50	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
HLCLCPOC_02076	8.09e-141	-	-	-	K	-	-	-	SIR2-like domain
HLCLCPOC_02077	1.89e-278	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLCLCPOC_02079	1.98e-40	-	-	-	-	-	-	-	-
HLCLCPOC_02082	1.7e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
HLCLCPOC_02083	4.65e-70	-	-	-	-	-	-	-	-
HLCLCPOC_02084	1.14e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HLCLCPOC_02085	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HLCLCPOC_02086	9.13e-262	-	-	-	S	-	-	-	Phage portal protein
HLCLCPOC_02087	0.000349	-	-	-	-	-	-	-	-
HLCLCPOC_02088	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HLCLCPOC_02089	9.03e-108	-	-	-	L	-	-	-	overlaps another CDS with the same product name
HLCLCPOC_02090	3.14e-90	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
HLCLCPOC_02091	1.88e-70	-	-	-	S	-	-	-	Head-tail joining protein
HLCLCPOC_02092	6.46e-37	-	-	-	-	-	-	-	-
HLCLCPOC_02093	6.85e-113	-	-	-	-	-	-	-	-
HLCLCPOC_02094	1.22e-280	-	-	-	S	-	-	-	Virulence-associated protein E
HLCLCPOC_02095	2.13e-187	-	-	-	L	-	-	-	DNA replication protein
HLCLCPOC_02096	4.71e-47	-	-	-	-	-	-	-	-
HLCLCPOC_02097	2.3e-12	-	-	-	-	-	-	-	-
HLCLCPOC_02099	0.000204	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HLCLCPOC_02100	2.54e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLCLCPOC_02101	1.28e-51	-	-	-	-	-	-	-	-
HLCLCPOC_02102	9.28e-58	-	-	-	-	-	-	-	-
HLCLCPOC_02103	1.27e-109	-	-	-	K	-	-	-	MarR family
HLCLCPOC_02104	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HLCLCPOC_02105	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HLCLCPOC_02106	6.58e-24	-	-	-	-	-	-	-	-
HLCLCPOC_02107	3.26e-24	-	-	-	-	-	-	-	-
HLCLCPOC_02108	1.56e-22	-	-	-	-	-	-	-	-
HLCLCPOC_02109	9.35e-24	-	-	-	-	-	-	-	-
HLCLCPOC_02110	9.35e-24	-	-	-	-	-	-	-	-
HLCLCPOC_02111	9.35e-24	-	-	-	-	-	-	-	-
HLCLCPOC_02112	2.16e-26	-	-	-	-	-	-	-	-
HLCLCPOC_02113	4.63e-24	-	-	-	-	-	-	-	-
HLCLCPOC_02114	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HLCLCPOC_02115	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLCLCPOC_02116	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02117	2.1e-33	-	-	-	-	-	-	-	-
HLCLCPOC_02118	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HLCLCPOC_02119	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HLCLCPOC_02120	1.5e-276	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HLCLCPOC_02121	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HLCLCPOC_02122	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HLCLCPOC_02123	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HLCLCPOC_02124	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HLCLCPOC_02125	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HLCLCPOC_02127	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HLCLCPOC_02128	1.53e-63	-	-	-	-	-	-	-	-
HLCLCPOC_02129	1.96e-273	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HLCLCPOC_02130	1.1e-175	-	-	-	F	-	-	-	NUDIX domain
HLCLCPOC_02131	2.68e-32	-	-	-	-	-	-	-	-
HLCLCPOC_02133	4.72e-206	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLCLCPOC_02134	1.37e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HLCLCPOC_02135	4.17e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HLCLCPOC_02136	2.29e-48	-	-	-	-	-	-	-	-
HLCLCPOC_02137	1.11e-45	-	-	-	-	-	-	-	-
HLCLCPOC_02138	2.21e-275	-	-	-	T	-	-	-	diguanylate cyclase
HLCLCPOC_02139	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HLCLCPOC_02140	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HLCLCPOC_02141	9.95e-108	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLCLCPOC_02142	3.22e-42	-	-	-	-	-	-	-	-
HLCLCPOC_02143	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HLCLCPOC_02144	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLCLCPOC_02145	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HLCLCPOC_02146	2.04e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HLCLCPOC_02147	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HLCLCPOC_02148	2.55e-212	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HLCLCPOC_02149	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_02150	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLCLCPOC_02151	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02152	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HLCLCPOC_02153	1.11e-201	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HLCLCPOC_02154	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HLCLCPOC_02155	7.09e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HLCLCPOC_02156	3.68e-256	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HLCLCPOC_02157	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HLCLCPOC_02158	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HLCLCPOC_02159	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLCLCPOC_02160	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HLCLCPOC_02161	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLCLCPOC_02162	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HLCLCPOC_02163	1.11e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HLCLCPOC_02164	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HLCLCPOC_02165	2.2e-273	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HLCLCPOC_02166	1.3e-207	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HLCLCPOC_02167	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
HLCLCPOC_02168	2.09e-212	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HLCLCPOC_02169	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HLCLCPOC_02170	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HLCLCPOC_02171	1.44e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLCLCPOC_02172	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HLCLCPOC_02173	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLCLCPOC_02174	3.17e-235	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLCLCPOC_02175	1.45e-46	-	-	-	-	-	-	-	-
HLCLCPOC_02176	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HLCLCPOC_02177	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HLCLCPOC_02178	0.0	-	-	-	M	-	-	-	domain protein
HLCLCPOC_02179	7.35e-99	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HLCLCPOC_02180	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLCLCPOC_02181	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HLCLCPOC_02182	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HLCLCPOC_02183	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLCLCPOC_02184	1.44e-247	-	-	-	S	-	-	-	domain, Protein
HLCLCPOC_02185	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HLCLCPOC_02186	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
HLCLCPOC_02187	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HLCLCPOC_02188	7.74e-205	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLCLCPOC_02189	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HLCLCPOC_02190	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HLCLCPOC_02191	3.24e-147	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HLCLCPOC_02192	5e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HLCLCPOC_02193	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HLCLCPOC_02194	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLCLCPOC_02195	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLCLCPOC_02196	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HLCLCPOC_02197	2.66e-172	-	-	-	-	-	-	-	-
HLCLCPOC_02198	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_02199	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HLCLCPOC_02200	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HLCLCPOC_02201	3.25e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HLCLCPOC_02202	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HLCLCPOC_02203	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_02204	7.58e-210	-	-	-	-	-	-	-	-
HLCLCPOC_02206	8.36e-74	-	-	-	-	-	-	-	-
HLCLCPOC_02207	8.34e-65	-	-	-	-	-	-	-	-
HLCLCPOC_02208	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLCLCPOC_02209	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HLCLCPOC_02210	4.27e-89	-	-	-	-	-	-	-	-
HLCLCPOC_02211	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HLCLCPOC_02212	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HLCLCPOC_02213	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HLCLCPOC_02214	3.89e-62	-	-	-	-	-	-	-	-
HLCLCPOC_02215	1.57e-71	-	-	-	-	-	-	-	-
HLCLCPOC_02216	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HLCLCPOC_02217	4.05e-98	-	-	-	-	-	-	-	-
HLCLCPOC_02218	4.15e-78	-	-	-	-	-	-	-	-
HLCLCPOC_02219	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HLCLCPOC_02220	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HLCLCPOC_02221	8.42e-102	uspA3	-	-	T	-	-	-	universal stress protein
HLCLCPOC_02222	8.36e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HLCLCPOC_02223	2.73e-24	-	-	-	-	-	-	-	-
HLCLCPOC_02224	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
HLCLCPOC_02225	9.66e-97	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HLCLCPOC_02226	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HLCLCPOC_02227	3.96e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HLCLCPOC_02228	1.85e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLCLCPOC_02229	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HLCLCPOC_02230	1.79e-212	-	-	-	S	-	-	-	Putative esterase
HLCLCPOC_02231	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_02232	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLCLCPOC_02233	6.08e-179	-	-	-	-	-	-	-	-
HLCLCPOC_02234	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLCLCPOC_02235	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HLCLCPOC_02236	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HLCLCPOC_02237	5.4e-80	-	-	-	-	-	-	-	-
HLCLCPOC_02238	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLCLCPOC_02239	2.97e-76	-	-	-	-	-	-	-	-
HLCLCPOC_02240	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HLCLCPOC_02241	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HLCLCPOC_02242	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLCLCPOC_02243	1.17e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HLCLCPOC_02244	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLCLCPOC_02245	2.19e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HLCLCPOC_02246	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HLCLCPOC_02247	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLCLCPOC_02248	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HLCLCPOC_02249	2.91e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLCLCPOC_02250	4.34e-203	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLCLCPOC_02251	3.59e-26	-	-	-	-	-	-	-	-
HLCLCPOC_02252	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLCLCPOC_02253	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HLCLCPOC_02254	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HLCLCPOC_02255	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HLCLCPOC_02256	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HLCLCPOC_02257	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HLCLCPOC_02258	9.44e-219	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HLCLCPOC_02259	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLCLCPOC_02260	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLCLCPOC_02261	2.99e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLCLCPOC_02262	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HLCLCPOC_02263	4.77e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HLCLCPOC_02264	1.38e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLCLCPOC_02265	3.5e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HLCLCPOC_02266	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLCLCPOC_02267	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HLCLCPOC_02268	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HLCLCPOC_02269	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HLCLCPOC_02270	4.71e-208	-	-	-	GM	-	-	-	NmrA-like family
HLCLCPOC_02271	1.25e-199	-	-	-	T	-	-	-	EAL domain
HLCLCPOC_02272	2.62e-121	-	-	-	-	-	-	-	-
HLCLCPOC_02273	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HLCLCPOC_02274	3.16e-158	-	-	-	E	-	-	-	Methionine synthase
HLCLCPOC_02275	6.66e-281	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HLCLCPOC_02276	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HLCLCPOC_02277	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLCLCPOC_02278	4.04e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HLCLCPOC_02279	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLCLCPOC_02280	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLCLCPOC_02281	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLCLCPOC_02282	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLCLCPOC_02283	3.95e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HLCLCPOC_02284	6.77e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLCLCPOC_02285	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLCLCPOC_02286	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HLCLCPOC_02287	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HLCLCPOC_02288	1.16e-242	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HLCLCPOC_02289	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HLCLCPOC_02290	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HLCLCPOC_02291	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLCLCPOC_02292	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HLCLCPOC_02293	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02294	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HLCLCPOC_02295	4.76e-56	-	-	-	-	-	-	-	-
HLCLCPOC_02296	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HLCLCPOC_02297	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02298	3.41e-190	-	-	-	-	-	-	-	-
HLCLCPOC_02299	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HLCLCPOC_02300	1.08e-47	-	-	-	-	-	-	-	-
HLCLCPOC_02301	4.69e-94	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HLCLCPOC_02302	1.02e-113	-	-	-	-	-	-	-	-
HLCLCPOC_02303	1.98e-65	-	-	-	-	-	-	-	-
HLCLCPOC_02304	4.79e-13	-	-	-	-	-	-	-	-
HLCLCPOC_02305	2.49e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HLCLCPOC_02306	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HLCLCPOC_02307	1.52e-151	-	-	-	-	-	-	-	-
HLCLCPOC_02308	1.21e-69	-	-	-	-	-	-	-	-
HLCLCPOC_02310	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HLCLCPOC_02311	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HLCLCPOC_02312	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HLCLCPOC_02313	2.96e-41	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HLCLCPOC_02314	2.05e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HLCLCPOC_02315	2.28e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HLCLCPOC_02316	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HLCLCPOC_02317	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HLCLCPOC_02318	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HLCLCPOC_02319	9.97e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HLCLCPOC_02320	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
HLCLCPOC_02321	6.73e-287	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HLCLCPOC_02322	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HLCLCPOC_02323	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLCLCPOC_02324	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_02325	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_02326	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HLCLCPOC_02327	2.48e-315	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HLCLCPOC_02328	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLCLCPOC_02329	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLCLCPOC_02330	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HLCLCPOC_02331	1.31e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HLCLCPOC_02332	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HLCLCPOC_02333	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HLCLCPOC_02334	1.44e-155	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HLCLCPOC_02335	7.63e-107	-	-	-	-	-	-	-	-
HLCLCPOC_02336	5.06e-196	-	-	-	S	-	-	-	hydrolase
HLCLCPOC_02337	1.51e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLCLCPOC_02338	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HLCLCPOC_02339	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HLCLCPOC_02340	1.99e-115	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HLCLCPOC_02341	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HLCLCPOC_02342	2.35e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HLCLCPOC_02343	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HLCLCPOC_02344	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HLCLCPOC_02345	4.3e-44	-	-	-	-	-	-	-	-
HLCLCPOC_02346	2.1e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HLCLCPOC_02347	0.0	ycaM	-	-	E	-	-	-	amino acid
HLCLCPOC_02348	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HLCLCPOC_02349	1.42e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HLCLCPOC_02350	5.11e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HLCLCPOC_02351	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_02353	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HLCLCPOC_02354	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HLCLCPOC_02355	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLCLCPOC_02356	1.27e-143	-	-	-	-	-	-	-	-
HLCLCPOC_02357	2.18e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HLCLCPOC_02358	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
HLCLCPOC_02359	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HLCLCPOC_02360	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HLCLCPOC_02361	8.28e-127	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HLCLCPOC_02362	1.46e-49	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HLCLCPOC_02363	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLCLCPOC_02364	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HLCLCPOC_02365	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HLCLCPOC_02366	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02367	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HLCLCPOC_02368	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HLCLCPOC_02369	1.02e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HLCLCPOC_02370	1.14e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLCLCPOC_02371	2.1e-114	-	-	-	S	-	-	-	Membrane
HLCLCPOC_02372	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLCLCPOC_02373	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HLCLCPOC_02374	3.71e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLCLCPOC_02375	1.28e-75	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLCLCPOC_02376	1.46e-162	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HLCLCPOC_02377	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HLCLCPOC_02378	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HLCLCPOC_02379	5e-130	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HLCLCPOC_02380	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HLCLCPOC_02381	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HLCLCPOC_02382	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HLCLCPOC_02383	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLCLCPOC_02385	7.51e-77	-	-	-	M	-	-	-	LysM domain
HLCLCPOC_02386	3.92e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HLCLCPOC_02387	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02388	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLCLCPOC_02389	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLCLCPOC_02390	1.16e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HLCLCPOC_02391	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HLCLCPOC_02392	1.27e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HLCLCPOC_02393	1.07e-301	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HLCLCPOC_02394	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HLCLCPOC_02395	4.97e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02397	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLCLCPOC_02398	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HLCLCPOC_02399	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLCLCPOC_02400	2.15e-144	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLCLCPOC_02401	8.4e-112	-	-	-	-	-	-	-	-
HLCLCPOC_02402	6.25e-112	yvbK	-	-	K	-	-	-	GNAT family
HLCLCPOC_02403	9.76e-50	-	-	-	-	-	-	-	-
HLCLCPOC_02404	1.63e-63	-	-	-	-	-	-	-	-
HLCLCPOC_02405	2.22e-144	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HLCLCPOC_02406	4.39e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HLCLCPOC_02407	7.79e-203	-	-	-	K	-	-	-	LysR substrate binding domain
HLCLCPOC_02408	1.46e-133	-	-	-	GM	-	-	-	NAD(P)H-binding
HLCLCPOC_02409	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HLCLCPOC_02410	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLCLCPOC_02411	1.15e-179	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HLCLCPOC_02412	3.56e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HLCLCPOC_02413	1.64e-95	-	-	-	C	-	-	-	Flavodoxin
HLCLCPOC_02414	9.71e-161	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
HLCLCPOC_02415	1.96e-119	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HLCLCPOC_02416	3.52e-109	-	-	-	GM	-	-	-	NAD(P)H-binding
HLCLCPOC_02417	3.9e-138	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HLCLCPOC_02418	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_02420	5.16e-32	-	-	-	C	-	-	-	Flavodoxin
HLCLCPOC_02421	2e-27	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLCLCPOC_02422	2.11e-148	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLCLCPOC_02423	5.09e-167	-	-	-	C	-	-	-	Aldo keto reductase
HLCLCPOC_02424	7.42e-177	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HLCLCPOC_02425	2.35e-175	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HLCLCPOC_02426	5.55e-106	-	-	-	GM	-	-	-	NAD(P)H-binding
HLCLCPOC_02427	9.34e-30	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLCLCPOC_02428	1.81e-94	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLCLCPOC_02429	1.12e-117	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HLCLCPOC_02430	2.21e-46	-	-	-	-	-	-	-	-
HLCLCPOC_02431	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLCLCPOC_02432	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HLCLCPOC_02433	7.47e-164	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HLCLCPOC_02434	5.69e-80	-	-	-	-	-	-	-	-
HLCLCPOC_02435	9.15e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HLCLCPOC_02436	9.49e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HLCLCPOC_02437	1.86e-132	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HLCLCPOC_02438	1e-246	-	-	-	C	-	-	-	Aldo/keto reductase family
HLCLCPOC_02440	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLCLCPOC_02441	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLCLCPOC_02442	3.04e-312	-	-	-	EGP	-	-	-	Major Facilitator
HLCLCPOC_02445	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HLCLCPOC_02446	3.09e-141	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HLCLCPOC_02447	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLCLCPOC_02448	1.3e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HLCLCPOC_02449	9.05e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HLCLCPOC_02450	7.2e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HLCLCPOC_02451	6.3e-169	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HLCLCPOC_02452	2.34e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLCLCPOC_02453	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HLCLCPOC_02454	1.9e-189	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HLCLCPOC_02455	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HLCLCPOC_02456	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HLCLCPOC_02457	2e-266	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HLCLCPOC_02458	2.78e-222	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLCLCPOC_02459	1.44e-226	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HLCLCPOC_02460	3.71e-111	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
HLCLCPOC_02461	1.1e-186	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
HLCLCPOC_02462	4.03e-297	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HLCLCPOC_02463	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HLCLCPOC_02464	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLCLCPOC_02465	6.11e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HLCLCPOC_02466	0.0	-	-	-	-	-	-	-	-
HLCLCPOC_02467	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HLCLCPOC_02468	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HLCLCPOC_02469	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HLCLCPOC_02470	2.82e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HLCLCPOC_02471	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLCLCPOC_02472	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HLCLCPOC_02473	2.59e-107	-	-	-	-	-	-	-	-
HLCLCPOC_02474	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLCLCPOC_02475	1.59e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLCLCPOC_02476	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLCLCPOC_02477	3.7e-30	-	-	-	-	-	-	-	-
HLCLCPOC_02478	1.84e-134	-	-	-	-	-	-	-	-
HLCLCPOC_02479	5.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain
HLCLCPOC_02480	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HLCLCPOC_02481	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HLCLCPOC_02482	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HLCLCPOC_02483	1.61e-183	-	-	-	S	-	-	-	zinc-ribbon domain
HLCLCPOC_02485	4.29e-50	-	-	-	-	-	-	-	-
HLCLCPOC_02486	8.58e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HLCLCPOC_02487	4.07e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HLCLCPOC_02488	0.0	-	-	-	I	-	-	-	acetylesterase activity
HLCLCPOC_02489	6.34e-301	-	-	-	M	-	-	-	Collagen binding domain
HLCLCPOC_02490	2.82e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
HLCLCPOC_02491	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HLCLCPOC_02492	3.53e-227	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HLCLCPOC_02493	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HLCLCPOC_02494	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HLCLCPOC_02495	4.54e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HLCLCPOC_02496	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HLCLCPOC_02497	5.24e-124	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HLCLCPOC_02498	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
HLCLCPOC_02499	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HLCLCPOC_02500	6.24e-152	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLCLCPOC_02501	4.78e-197	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLCLCPOC_02502	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_02503	0.0	-	-	-	-	-	-	-	-
HLCLCPOC_02504	1.4e-82	-	-	-	-	-	-	-	-
HLCLCPOC_02505	2.62e-240	-	-	-	S	-	-	-	Cell surface protein
HLCLCPOC_02506	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HLCLCPOC_02507	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HLCLCPOC_02508	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLCLCPOC_02509	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HLCLCPOC_02510	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HLCLCPOC_02511	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HLCLCPOC_02512	4.23e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HLCLCPOC_02514	1.15e-43	-	-	-	-	-	-	-	-
HLCLCPOC_02515	2.93e-169	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HLCLCPOC_02516	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HLCLCPOC_02517	4.08e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLCLCPOC_02518	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLCLCPOC_02519	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLCLCPOC_02520	7.03e-62	-	-	-	-	-	-	-	-
HLCLCPOC_02521	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HLCLCPOC_02522	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HLCLCPOC_02523	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HLCLCPOC_02524	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02525	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HLCLCPOC_02526	4.8e-83	-	-	-	-	-	-	-	-
HLCLCPOC_02527	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HLCLCPOC_02528	1.21e-73	-	-	-	-	-	-	-	-
HLCLCPOC_02529	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HLCLCPOC_02530	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLCLCPOC_02531	8.23e-41	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLCLCPOC_02532	2.26e-99	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HLCLCPOC_02533	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HLCLCPOC_02534	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_02535	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLCLCPOC_02536	7.8e-238	-	-	-	GM	-	-	-	Male sterility protein
HLCLCPOC_02537	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLCLCPOC_02538	4.61e-101	-	-	-	M	-	-	-	LysM domain
HLCLCPOC_02539	1.43e-56	-	-	-	M	-	-	-	Lysin motif
HLCLCPOC_02540	7.68e-45	-	-	-	M	-	-	-	Lysin motif
HLCLCPOC_02541	1.4e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HLCLCPOC_02542	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HLCLCPOC_02543	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLCLCPOC_02544	3.57e-120	-	-	-	-	-	-	-	-
HLCLCPOC_02545	1.35e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HLCLCPOC_02546	6.14e-282	-	-	-	T	-	-	-	diguanylate cyclase
HLCLCPOC_02547	5.23e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLCLCPOC_02548	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HLCLCPOC_02549	8.21e-215	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HLCLCPOC_02550	4.33e-95	-	-	-	-	-	-	-	-
HLCLCPOC_02551	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLCLCPOC_02552	3.79e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HLCLCPOC_02553	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HLCLCPOC_02554	1.17e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HLCLCPOC_02555	5.51e-101	yphH	-	-	S	-	-	-	Cupin domain
HLCLCPOC_02556	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
HLCLCPOC_02557	3.83e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HLCLCPOC_02558	8.04e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
HLCLCPOC_02559	2.31e-277	-	-	-	-	-	-	-	-
HLCLCPOC_02560	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLCLCPOC_02561	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02562	1.65e-21	-	-	-	-	-	-	-	-
HLCLCPOC_02563	2.09e-286	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HLCLCPOC_02564	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
HLCLCPOC_02566	3.27e-91	-	-	-	-	-	-	-	-
HLCLCPOC_02567	1.01e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLCLCPOC_02568	0.0	-	-	-	E	-	-	-	Amino Acid
HLCLCPOC_02569	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HLCLCPOC_02570	1.16e-49	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HLCLCPOC_02571	1.41e-199	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HLCLCPOC_02572	1.31e-269	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HLCLCPOC_02573	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HLCLCPOC_02574	2.04e-56	-	-	-	S	-	-	-	Cupredoxin-like domain
HLCLCPOC_02575	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HLCLCPOC_02576	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HLCLCPOC_02577	3.28e-180	-	-	-	K	-	-	-	Helix-turn-helix domain
HLCLCPOC_02578	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HLCLCPOC_02579	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HLCLCPOC_02580	0.0	-	-	-	-	-	-	-	-
HLCLCPOC_02581	2.69e-99	-	-	-	-	-	-	-	-
HLCLCPOC_02582	2.85e-243	-	-	-	S	-	-	-	Cell surface protein
HLCLCPOC_02583	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HLCLCPOC_02584	1.33e-225	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HLCLCPOC_02585	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HLCLCPOC_02586	1.36e-148	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HLCLCPOC_02587	2.63e-242	ynjC	-	-	S	-	-	-	Cell surface protein
HLCLCPOC_02588	4.48e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HLCLCPOC_02589	1.47e-83	-	-	-	-	-	-	-	-
HLCLCPOC_02590	8.15e-306	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HLCLCPOC_02591	4.13e-157	-	-	-	-	-	-	-	-
HLCLCPOC_02592	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HLCLCPOC_02593	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLCLCPOC_02594	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
HLCLCPOC_02595	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HLCLCPOC_02596	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLCLCPOC_02597	4.63e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HLCLCPOC_02598	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HLCLCPOC_02599	3.21e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_02600	4.4e-215	-	-	-	GM	-	-	-	NmrA-like family
HLCLCPOC_02601	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLCLCPOC_02602	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HLCLCPOC_02603	2.7e-61	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HLCLCPOC_02604	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HLCLCPOC_02605	3.27e-170	-	-	-	S	-	-	-	KR domain
HLCLCPOC_02606	2.46e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_02607	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HLCLCPOC_02608	2.19e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HLCLCPOC_02609	1.97e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
HLCLCPOC_02610	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HLCLCPOC_02611	2.64e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_02612	7.05e-219	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HLCLCPOC_02613	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLCLCPOC_02614	1.81e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLCLCPOC_02615	1.58e-217	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLCLCPOC_02616	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_02617	3.89e-210	-	-	-	GM	-	-	-	NmrA-like family
HLCLCPOC_02618	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLCLCPOC_02619	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HLCLCPOC_02620	1.83e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLCLCPOC_02621	3.86e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLCLCPOC_02622	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLCLCPOC_02623	4.28e-233	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HLCLCPOC_02624	4.49e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HLCLCPOC_02625	1.12e-253	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HLCLCPOC_02626	5.65e-151	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_02627	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLCLCPOC_02628	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLCLCPOC_02629	7.53e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HLCLCPOC_02630	4.71e-209	-	-	-	K	-	-	-	LysR substrate binding domain
HLCLCPOC_02631	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HLCLCPOC_02632	0.0	-	-	-	S	-	-	-	MucBP domain
HLCLCPOC_02633	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HLCLCPOC_02634	1.85e-41	-	-	-	-	-	-	-	-
HLCLCPOC_02636	1.43e-186	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HLCLCPOC_02637	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLCLCPOC_02638	0.0	-	-	-	G	ko:K02752,ko:K02753,ko:K02755,ko:K02756,ko:K02757	ko00010,ko02060,map00010,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLCLCPOC_02639	1.53e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HLCLCPOC_02640	0.0	-	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLCLCPOC_02641	8.26e-307	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HLCLCPOC_02642	2.61e-64	sgaB	2.7.1.194, 2.7.1.200	-	G	ko:K02774,ko:K02822,ko:K03475	ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HLCLCPOC_02643	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLCLCPOC_02644	1.91e-280	-	-	-	S	-	-	-	Membrane
HLCLCPOC_02645	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HLCLCPOC_02646	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HLCLCPOC_02647	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HLCLCPOC_02648	7.55e-76	-	-	-	-	-	-	-	-
HLCLCPOC_02649	2.06e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HLCLCPOC_02650	6.14e-65	-	-	-	K	-	-	-	Helix-turn-helix domain
HLCLCPOC_02651	5.49e-261	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HLCLCPOC_02652	2.4e-112	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HLCLCPOC_02653	3.29e-154	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HLCLCPOC_02654	4.01e-142	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HLCLCPOC_02655	1.93e-139	-	-	-	GM	-	-	-	NAD(P)H-binding
HLCLCPOC_02656	8.89e-101	-	-	-	GM	-	-	-	SnoaL-like domain
HLCLCPOC_02657	0.0	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
HLCLCPOC_02658	2.52e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HLCLCPOC_02659	7.9e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_02660	1.34e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HLCLCPOC_02661	8.53e-45	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HLCLCPOC_02663	6.79e-53	-	-	-	-	-	-	-	-
HLCLCPOC_02664	4.13e-42	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLCLCPOC_02666	1.61e-12	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	Reverse transcriptase (RNA-dependent DNA polymerase)
HLCLCPOC_02667	1.71e-170	int3	-	-	L	-	-	-	Phage integrase SAM-like domain
HLCLCPOC_02670	8.82e-45	-	-	-	-	-	-	-	-
HLCLCPOC_02671	1.42e-100	-	-	-	-	-	-	-	-
HLCLCPOC_02673	9.76e-39	-	-	-	-	-	-	-	-
HLCLCPOC_02674	1.51e-30	-	-	-	S	-	-	-	Mor transcription activator family
HLCLCPOC_02675	1.78e-13	-	-	-	-	-	-	-	-
HLCLCPOC_02676	1.44e-16	-	-	-	S	-	-	-	Mor transcription activator family
HLCLCPOC_02678	2.35e-56	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLCLCPOC_02679	2.67e-265	-	-	-	S	-	-	-	Membrane
HLCLCPOC_02680	3e-222	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
HLCLCPOC_02682	2.34e-64	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
HLCLCPOC_02683	2.61e-66	-	-	-	-	ko:K19174	-	ko00000,ko02048	-
HLCLCPOC_02684	6.46e-79	-	-	-	L	ko:K19173	-	ko00000,ko02048	COG0433 Predicted ATPase
HLCLCPOC_02685	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HLCLCPOC_02686	1.4e-199	is18	-	-	L	-	-	-	Integrase core domain
HLCLCPOC_02687	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLCLCPOC_02688	6.52e-69	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HLCLCPOC_02689	5.82e-46	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_02690	1.67e-148	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
HLCLCPOC_02691	6.11e-09	-	-	-	S	-	-	-	Domain of unknown function (DUF4260)
HLCLCPOC_02692	1.11e-81	-	-	-	S	-	-	-	PFAM Metallo-beta-lactamase superfamily
HLCLCPOC_02693	5.02e-52	-	-	-	-	-	-	-	-
HLCLCPOC_02694	1.94e-153	-	-	-	Q	-	-	-	Methyltransferase domain
HLCLCPOC_02695	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLCLCPOC_02696	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HLCLCPOC_02697	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HLCLCPOC_02698	5.02e-151	-	-	-	-	-	-	-	-
HLCLCPOC_02699	4.45e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HLCLCPOC_02700	1.41e-211	-	-	-	-	-	-	-	-
HLCLCPOC_02701	2.27e-257	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HLCLCPOC_02702	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HLCLCPOC_02703	1.01e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HLCLCPOC_02704	2.29e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLCLCPOC_02706	5.01e-71	-	-	-	-	-	-	-	-
HLCLCPOC_02707	9.65e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLCLCPOC_02708	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HLCLCPOC_02709	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HLCLCPOC_02710	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HLCLCPOC_02711	3.61e-303	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLCLCPOC_02712	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HLCLCPOC_02713	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HLCLCPOC_02714	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HLCLCPOC_02715	1.91e-207	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLCLCPOC_02716	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLCLCPOC_02717	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HLCLCPOC_02718	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLCLCPOC_02719	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HLCLCPOC_02720	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLCLCPOC_02721	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HLCLCPOC_02722	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLCLCPOC_02723	4.27e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HLCLCPOC_02724	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HLCLCPOC_02725	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HLCLCPOC_02726	3.66e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLCLCPOC_02727	1.37e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HLCLCPOC_02728	5.69e-300	-	-	-	EK	-	-	-	Aminotransferase, class I
HLCLCPOC_02729	6.12e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HLCLCPOC_02730	8.59e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLCLCPOC_02731	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02732	3.6e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HLCLCPOC_02733	8.83e-127	-	-	-	KT	-	-	-	response to antibiotic
HLCLCPOC_02734	8.52e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HLCLCPOC_02735	6.03e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HLCLCPOC_02736	9.68e-202	-	-	-	S	-	-	-	Putative adhesin
HLCLCPOC_02737	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLCLCPOC_02738	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HLCLCPOC_02739	6.39e-234	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HLCLCPOC_02740	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HLCLCPOC_02741	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HLCLCPOC_02742	5.06e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLCLCPOC_02743	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLCLCPOC_02744	6.26e-101	-	-	-	-	-	-	-	-
HLCLCPOC_02745	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HLCLCPOC_02746	3.03e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HLCLCPOC_02747	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HLCLCPOC_02748	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HLCLCPOC_02749	1.35e-154	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HLCLCPOC_02750	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HLCLCPOC_02751	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HLCLCPOC_02752	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLCLCPOC_02753	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HLCLCPOC_02754	1.25e-198	-	-	-	GM	-	-	-	NmrA-like family
HLCLCPOC_02755	1.43e-44	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLCLCPOC_02756	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLCLCPOC_02757	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HLCLCPOC_02759	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HLCLCPOC_02760	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
HLCLCPOC_02761	1.16e-135	-	-	-	-	-	-	-	-
HLCLCPOC_02762	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HLCLCPOC_02763	7.43e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HLCLCPOC_02764	3.08e-47	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HLCLCPOC_02765	4.59e-216	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HLCLCPOC_02766	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HLCLCPOC_02767	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HLCLCPOC_02768	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HLCLCPOC_02769	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HLCLCPOC_02770	1.03e-34	-	-	-	-	-	-	-	-
HLCLCPOC_02771	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HLCLCPOC_02772	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HLCLCPOC_02773	2.85e-210	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HLCLCPOC_02774	3.85e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HLCLCPOC_02775	3.51e-252	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HLCLCPOC_02776	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HLCLCPOC_02777	8.36e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HLCLCPOC_02778	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLCLCPOC_02779	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLCLCPOC_02780	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLCLCPOC_02781	2.5e-188	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HLCLCPOC_02782	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLCLCPOC_02784	1.18e-82	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_02785	1.12e-186	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
HLCLCPOC_02786	2.45e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HLCLCPOC_02787	7.97e-108	-	-	-	-	-	-	-	-
HLCLCPOC_02788	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HLCLCPOC_02790	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HLCLCPOC_02791	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLCLCPOC_02792	2.19e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HLCLCPOC_02793	5.85e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HLCLCPOC_02794	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HLCLCPOC_02795	2.8e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HLCLCPOC_02796	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HLCLCPOC_02797	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HLCLCPOC_02798	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HLCLCPOC_02799	6.62e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLCLCPOC_02801	8.03e-28	-	-	-	-	-	-	-	-
HLCLCPOC_02802	1.59e-123	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HLCLCPOC_02803	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HLCLCPOC_02804	3.47e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HLCLCPOC_02805	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HLCLCPOC_02806	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HLCLCPOC_02807	1.3e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HLCLCPOC_02808	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLCLCPOC_02809	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HLCLCPOC_02810	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLCLCPOC_02811	4.41e-316	-	-	-	EGP	-	-	-	Major Facilitator
HLCLCPOC_02813	4.54e-54	-	-	-	-	-	-	-	-
HLCLCPOC_02814	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HLCLCPOC_02815	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HLCLCPOC_02816	4.41e-248	-	-	-	V	-	-	-	Beta-lactamase
HLCLCPOC_02817	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HLCLCPOC_02818	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLCLCPOC_02819	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HLCLCPOC_02820	7.39e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
HLCLCPOC_02821	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HLCLCPOC_02822	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HLCLCPOC_02823	4.29e-101	-	-	-	-	-	-	-	-
HLCLCPOC_02824	1.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HLCLCPOC_02825	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HLCLCPOC_02826	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HLCLCPOC_02828	2.82e-161	-	-	-	S	-	-	-	YjbR
HLCLCPOC_02829	3.19e-283	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HLCLCPOC_02830	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HLCLCPOC_02831	5.84e-255	glmS2	-	-	M	-	-	-	SIS domain
HLCLCPOC_02832	3.58e-36	-	-	-	S	-	-	-	Belongs to the LOG family
HLCLCPOC_02833	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HLCLCPOC_02834	9.04e-317	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HLCLCPOC_02835	2.48e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLCLCPOC_02836	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HLCLCPOC_02837	1.36e-209	-	-	-	GM	-	-	-	NmrA-like family
HLCLCPOC_02838	4.31e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HLCLCPOC_02839	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HLCLCPOC_02840	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HLCLCPOC_02841	1.7e-70	-	-	-	-	-	-	-	-
HLCLCPOC_02842	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HLCLCPOC_02843	2.11e-82	-	-	-	-	-	-	-	-
HLCLCPOC_02844	1.36e-112	-	-	-	-	-	-	-	-
HLCLCPOC_02845	3.22e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLCLCPOC_02846	2.27e-74	-	-	-	-	-	-	-	-
HLCLCPOC_02847	4.79e-21	-	-	-	-	-	-	-	-
HLCLCPOC_02848	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HLCLCPOC_02849	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HLCLCPOC_02850	1.63e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HLCLCPOC_02851	2.66e-155	-	-	-	S	-	-	-	membrane
HLCLCPOC_02852	2.55e-145	-	-	-	S	-	-	-	VIT family
HLCLCPOC_02853	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HLCLCPOC_02854	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HLCLCPOC_02855	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HLCLCPOC_02856	4.26e-54	-	-	-	-	-	-	-	-
HLCLCPOC_02857	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HLCLCPOC_02858	1.45e-313	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HLCLCPOC_02859	7.21e-35	-	-	-	-	-	-	-	-
HLCLCPOC_02860	2.55e-65	-	-	-	-	-	-	-	-
HLCLCPOC_02861	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HLCLCPOC_02862	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HLCLCPOC_02863	2.52e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HLCLCPOC_02864	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HLCLCPOC_02865	1.18e-98	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HLCLCPOC_02866	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HLCLCPOC_02867	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HLCLCPOC_02868	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLCLCPOC_02869	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLCLCPOC_02870	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HLCLCPOC_02871	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HLCLCPOC_02872	2.93e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HLCLCPOC_02873	1.21e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HLCLCPOC_02874	5.43e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HLCLCPOC_02875	4.88e-117	ymdB	-	-	S	-	-	-	Macro domain protein
HLCLCPOC_02876	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HLCLCPOC_02877	1.58e-66	-	-	-	-	-	-	-	-
HLCLCPOC_02878	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HLCLCPOC_02879	0.0	-	-	-	-	-	-	-	-
HLCLCPOC_02880	1.36e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HLCLCPOC_02881	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HLCLCPOC_02882	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HLCLCPOC_02883	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HLCLCPOC_02884	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLCLCPOC_02885	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HLCLCPOC_02886	4.45e-38	-	-	-	-	-	-	-	-
HLCLCPOC_02887	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HLCLCPOC_02888	2.04e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
HLCLCPOC_02889	6.18e-71	-	-	-	-	-	-	-	-
HLCLCPOC_02890	9.96e-82	-	-	-	-	-	-	-	-
HLCLCPOC_02892	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLCLCPOC_02893	6.97e-68	-	-	-	-	-	-	-	-
HLCLCPOC_02894	4.99e-52	-	-	-	-	-	-	-	-
HLCLCPOC_02895	1.22e-68	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HLCLCPOC_02896	7.98e-205	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HLCLCPOC_02897	8.52e-130	-	-	-	K	-	-	-	transcriptional regulator
HLCLCPOC_02898	1.24e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HLCLCPOC_02899	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLCLCPOC_02900	3.04e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HLCLCPOC_02901	2.93e-234	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HLCLCPOC_02902	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HLCLCPOC_02903	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLCLCPOC_02904	9.52e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HLCLCPOC_02905	6.85e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HLCLCPOC_02906	1.01e-26	-	-	-	-	-	-	-	-
HLCLCPOC_02907	2.03e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HLCLCPOC_02908	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HLCLCPOC_02909	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HLCLCPOC_02910	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HLCLCPOC_02911	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HLCLCPOC_02912	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HLCLCPOC_02913	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HLCLCPOC_02914	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HLCLCPOC_02915	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HLCLCPOC_02916	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HLCLCPOC_02917	7.83e-60	-	-	-	-	-	-	-	-
HLCLCPOC_02918	1.72e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HLCLCPOC_02919	1.03e-65	-	-	-	-	-	-	-	-
HLCLCPOC_02920	1.87e-316	-	-	-	S	-	-	-	Putative metallopeptidase domain
HLCLCPOC_02921	4.03e-283	-	-	-	S	-	-	-	associated with various cellular activities
HLCLCPOC_02922	1.6e-139	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLCLCPOC_02923	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HLCLCPOC_02924	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLCLCPOC_02925	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HLCLCPOC_02926	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HLCLCPOC_02927	1.11e-240	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLCLCPOC_02928	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HLCLCPOC_02929	5.63e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HLCLCPOC_02930	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HLCLCPOC_02931	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HLCLCPOC_02932	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLCLCPOC_02933	3.9e-143	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HLCLCPOC_02934	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HLCLCPOC_02935	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLCLCPOC_02936	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HLCLCPOC_02937	2.97e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HLCLCPOC_02938	3.32e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLCLCPOC_02939	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HLCLCPOC_02940	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HLCLCPOC_02941	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HLCLCPOC_02942	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HLCLCPOC_02943	7.07e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HLCLCPOC_02944	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLCLCPOC_02945	1.48e-247	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HLCLCPOC_02946	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HLCLCPOC_02947	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HLCLCPOC_02948	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLCLCPOC_02949	2.11e-171	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HLCLCPOC_02950	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLCLCPOC_02951	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HLCLCPOC_02952	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLCLCPOC_02953	1.2e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLCLCPOC_02954	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLCLCPOC_02955	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HLCLCPOC_02956	5.56e-212	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HLCLCPOC_02957	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HLCLCPOC_02958	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLCLCPOC_02959	2.09e-83	-	-	-	-	-	-	-	-
HLCLCPOC_02960	2.53e-198	estA	-	-	S	-	-	-	Putative esterase
HLCLCPOC_02961	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HLCLCPOC_02962	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLCLCPOC_02963	6.89e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HLCLCPOC_02964	1.69e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HLCLCPOC_02965	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HLCLCPOC_02966	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLCLCPOC_02967	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLCLCPOC_02968	8.75e-199	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HLCLCPOC_02969	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLCLCPOC_02970	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLCLCPOC_02971	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLCLCPOC_02972	1.85e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HLCLCPOC_02973	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HLCLCPOC_02974	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLCLCPOC_02975	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HLCLCPOC_02976	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HLCLCPOC_02978	2.83e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLCLCPOC_02979	7.09e-184	yxeH	-	-	S	-	-	-	hydrolase
HLCLCPOC_02980	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLCLCPOC_02981	1.68e-146	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HLCLCPOC_02982	1.43e-306	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HLCLCPOC_02983	1.04e-60	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HLCLCPOC_02984	6.42e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLCLCPOC_02985	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLCLCPOC_02986	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HLCLCPOC_02987	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HLCLCPOC_02988	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HLCLCPOC_02989	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HLCLCPOC_02990	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLCLCPOC_02991	3.05e-161	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HLCLCPOC_02992	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HLCLCPOC_02993	1.73e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HLCLCPOC_02994	6.83e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HLCLCPOC_02995	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HLCLCPOC_02996	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HLCLCPOC_02997	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HLCLCPOC_02998	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLCLCPOC_02999	3.44e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HLCLCPOC_03000	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HLCLCPOC_03001	1.13e-291	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HLCLCPOC_03002	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HLCLCPOC_03003	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HLCLCPOC_03004	1.06e-16	-	-	-	-	-	-	-	-
HLCLCPOC_03005	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HLCLCPOC_03006	7.17e-187	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HLCLCPOC_03007	4.32e-163	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HLCLCPOC_03008	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HLCLCPOC_03009	4.29e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HLCLCPOC_03010	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HLCLCPOC_03011	9.62e-19	-	-	-	-	-	-	-	-
HLCLCPOC_03012	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HLCLCPOC_03013	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HLCLCPOC_03015	1.14e-255	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HLCLCPOC_03016	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HLCLCPOC_03017	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HLCLCPOC_03018	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HLCLCPOC_03019	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HLCLCPOC_03020	5.04e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HLCLCPOC_03021	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HLCLCPOC_03022	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HLCLCPOC_03023	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HLCLCPOC_03024	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HLCLCPOC_03025	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HLCLCPOC_03026	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HLCLCPOC_03027	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLCLCPOC_03028	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HLCLCPOC_03029	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HLCLCPOC_03030	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HLCLCPOC_03031	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HLCLCPOC_03032	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HLCLCPOC_03033	1e-180	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HLCLCPOC_03034	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLCLCPOC_03035	4.02e-203	degV1	-	-	S	-	-	-	DegV family
HLCLCPOC_03036	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HLCLCPOC_03037	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HLCLCPOC_03039	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLCLCPOC_03040	0.0	-	-	-	-	-	-	-	-
HLCLCPOC_03042	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HLCLCPOC_03043	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
HLCLCPOC_03044	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLCLCPOC_03045	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLCLCPOC_03046	5.56e-172	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HLCLCPOC_03047	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLCLCPOC_03048	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLCLCPOC_03049	0.0	-	-	-	L	-	-	-	MobA MobL family protein
HLCLCPOC_03050	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HLCLCPOC_03051	1.11e-45	-	-	-	-	-	-	-	-
HLCLCPOC_03052	3.45e-245	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HLCLCPOC_03053	3.64e-33	-	-	-	-	-	-	-	-
HLCLCPOC_03055	1.27e-10	-	-	-	S	-	-	-	Putative Holin-like Toxin (Hol-Tox)
HLCLCPOC_03057	4.68e-71	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HLCLCPOC_03058	3.81e-66	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLCLCPOC_03059	8.36e-90	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HLCLCPOC_03060	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HLCLCPOC_03061	4.23e-190	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLCLCPOC_03062	2.95e-72	-	-	-	L	-	-	-	Domain of unknown function (DUF4158)
HLCLCPOC_03063	1.57e-75	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	Helix-turn-helix domain
HLCLCPOC_03064	0.0	arsA	3.6.3.16	-	D	ko:K01551	-	ko00000,ko01000,ko02000	Anion-transporting ATPase
HLCLCPOC_03065	3.42e-275	arsB	-	-	U	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HLCLCPOC_03066	3.16e-11	arsB	-	-	U	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HLCLCPOC_03067	2.47e-74	-	-	-	S	-	-	-	Arsenical resistance operon trans-acting repressor ArsD
HLCLCPOC_03068	2.14e-97	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLCLCPOC_03069	3.79e-26	-	-	-	-	-	-	-	-
HLCLCPOC_03070	6.96e-211	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HLCLCPOC_03071	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HLCLCPOC_03072	1.9e-45	-	-	-	L	ko:K07483	-	ko00000	Transposase
HLCLCPOC_03073	1.19e-177	-	-	-	L	-	-	-	Integrase core domain
HLCLCPOC_03074	5.69e-72	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HLCLCPOC_03076	1.65e-134	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HLCLCPOC_03077	6.93e-194	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HLCLCPOC_03078	3.57e-47	-	-	-	-	-	-	-	-
HLCLCPOC_03079	4.66e-228	repA	-	-	S	-	-	-	Replication initiator protein A
HLCLCPOC_03080	2.83e-58	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
HLCLCPOC_03081	1.35e-38	-	-	-	-	-	-	-	-
HLCLCPOC_03082	1.63e-162	-	-	-	S	-	-	-	protein conserved in bacteria
HLCLCPOC_03083	1.45e-54	-	-	-	-	-	-	-	-
HLCLCPOC_03084	1.69e-37	-	-	-	-	-	-	-	-