ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NNGKMAKP_00001 3.46e-39 - - - S - - - Belongs to the HesB IscA family
NNGKMAKP_00002 3.65e-86 icaB - - G - - - Polysaccharide deacetylase
NNGKMAKP_00004 3.12e-68 - - - K - - - LysR substrate binding domain
NNGKMAKP_00005 3.35e-152 - - - S - - - Conserved hypothetical protein 698
NNGKMAKP_00006 2.06e-253 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
NNGKMAKP_00007 3.1e-137 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNGKMAKP_00008 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NNGKMAKP_00009 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NNGKMAKP_00010 1.1e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NNGKMAKP_00011 1.81e-201 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NNGKMAKP_00012 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NNGKMAKP_00013 1.69e-193 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NNGKMAKP_00014 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNGKMAKP_00015 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNGKMAKP_00016 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NNGKMAKP_00017 6.48e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NNGKMAKP_00018 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NNGKMAKP_00019 1.5e-140 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
NNGKMAKP_00020 3.81e-147 - - - S - - - Glycosyl transferase family 2
NNGKMAKP_00021 2.26e-81 - - - D - - - peptidase
NNGKMAKP_00022 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NNGKMAKP_00023 4.74e-74 - - - - - - - -
NNGKMAKP_00024 9.13e-51 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NNGKMAKP_00025 2.22e-30 - - - S - - - Cytochrome B5
NNGKMAKP_00027 3.85e-80 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NNGKMAKP_00028 1.1e-242 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNGKMAKP_00029 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NNGKMAKP_00030 1.42e-135 yueF - - S - - - AI-2E family transporter
NNGKMAKP_00031 3.8e-201 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NNGKMAKP_00032 3.64e-144 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NNGKMAKP_00033 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NNGKMAKP_00034 5.7e-39 - - - - - - - -
NNGKMAKP_00035 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
NNGKMAKP_00036 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NNGKMAKP_00037 6.71e-24 galR - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NNGKMAKP_00038 8.35e-105 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NNGKMAKP_00039 1.3e-226 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NNGKMAKP_00040 4.41e-208 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NNGKMAKP_00041 4.02e-251 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NNGKMAKP_00042 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NNGKMAKP_00043 6.64e-131 - - - G - - - MucBP domain
NNGKMAKP_00044 4.34e-32 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
NNGKMAKP_00045 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
NNGKMAKP_00046 2.13e-22 - - - - - - - -
NNGKMAKP_00047 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NNGKMAKP_00048 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NNGKMAKP_00049 8.96e-204 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NNGKMAKP_00050 2.25e-164 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NNGKMAKP_00051 8.79e-166 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNGKMAKP_00052 3.45e-36 ykuJ - - S - - - Protein of unknown function (DUF1797)
NNGKMAKP_00053 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NNGKMAKP_00056 2.32e-109 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNGKMAKP_00057 1.95e-88 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NNGKMAKP_00058 2.8e-56 yodB - - K - - - Transcriptional regulator, HxlR family
NNGKMAKP_00059 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NNGKMAKP_00060 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNGKMAKP_00061 4.65e-163 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NNGKMAKP_00062 2.49e-126 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NNGKMAKP_00063 2e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNGKMAKP_00064 5.6e-17 - - - - - - - -
NNGKMAKP_00065 7.14e-183 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
NNGKMAKP_00066 5.19e-56 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
NNGKMAKP_00067 3.09e-149 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NNGKMAKP_00068 4.09e-95 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NNGKMAKP_00069 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NNGKMAKP_00070 3.59e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NNGKMAKP_00071 7.29e-72 yjcF - - J - - - HAD-hyrolase-like
NNGKMAKP_00072 9.43e-57 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NNGKMAKP_00073 1.19e-164 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNGKMAKP_00074 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NNGKMAKP_00075 1.07e-256 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NNGKMAKP_00076 2.6e-141 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NNGKMAKP_00077 5.97e-237 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NNGKMAKP_00078 1.5e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NNGKMAKP_00079 1.43e-112 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NNGKMAKP_00080 1.34e-172 - - - K - - - Transcriptional regulator
NNGKMAKP_00081 7.65e-185 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NNGKMAKP_00082 2.84e-148 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NNGKMAKP_00083 4.96e-219 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNGKMAKP_00084 3.69e-113 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NNGKMAKP_00086 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NNGKMAKP_00087 2.69e-218 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NNGKMAKP_00088 6.27e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NNGKMAKP_00089 2.06e-34 - - - S - - - Family of unknown function (DUF5322)
NNGKMAKP_00090 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NNGKMAKP_00091 2.15e-51 - - - - - - - -
NNGKMAKP_00095 3.89e-183 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
NNGKMAKP_00096 4.83e-98 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NNGKMAKP_00097 6.65e-131 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NNGKMAKP_00098 4.12e-231 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NNGKMAKP_00099 6.31e-93 - - - L - - - DNA alkylation repair enzyme
NNGKMAKP_00100 2.44e-174 - - - EG - - - EamA-like transporter family
NNGKMAKP_00101 3.9e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NNGKMAKP_00102 1.56e-256 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NNGKMAKP_00103 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NNGKMAKP_00104 1.24e-173 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NNGKMAKP_00105 5.68e-215 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NNGKMAKP_00106 9.91e-165 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NNGKMAKP_00107 1.21e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NNGKMAKP_00109 1.26e-119 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NNGKMAKP_00110 8.18e-202 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NNGKMAKP_00111 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
NNGKMAKP_00112 5.64e-256 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NNGKMAKP_00113 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NNGKMAKP_00114 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
NNGKMAKP_00115 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NNGKMAKP_00116 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NNGKMAKP_00117 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NNGKMAKP_00119 3.22e-53 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NNGKMAKP_00120 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NNGKMAKP_00121 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNGKMAKP_00122 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNGKMAKP_00123 3.11e-252 FbpA - - K - - - Fibronectin-binding protein
NNGKMAKP_00124 2.07e-52 - - - K - - - Transcriptional regulator
NNGKMAKP_00125 1.69e-147 - - - S - - - EDD domain protein, DegV family
NNGKMAKP_00126 2.25e-90 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
NNGKMAKP_00127 7.78e-53 - - - S - - - ASCH
NNGKMAKP_00128 3.05e-235 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NNGKMAKP_00129 1.16e-97 - - - S - - - Calcineurin-like phosphoesterase
NNGKMAKP_00130 2.08e-121 - - - EG - - - EamA-like transporter family
NNGKMAKP_00131 9.69e-102 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-type Na efflux pump, permease component
NNGKMAKP_00132 5.68e-141 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
NNGKMAKP_00133 2.83e-26 - - - K - - - Psort location Cytoplasmic, score
NNGKMAKP_00135 2.02e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNGKMAKP_00136 2.36e-288 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NNGKMAKP_00137 3.19e-220 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NNGKMAKP_00138 2.98e-77 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphatase family
NNGKMAKP_00139 1.65e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NNGKMAKP_00140 2.74e-39 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKMAKP_00141 1.36e-222 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NNGKMAKP_00142 6.2e-276 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKMAKP_00144 6.69e-115 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NNGKMAKP_00145 4.63e-199 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NNGKMAKP_00146 5.92e-40 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NNGKMAKP_00147 2.42e-88 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NNGKMAKP_00148 5.08e-197 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NNGKMAKP_00149 1.39e-104 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
NNGKMAKP_00150 3.58e-112 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NNGKMAKP_00151 1.1e-25 - - - M - - - Lysin motif
NNGKMAKP_00152 1.5e-154 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NNGKMAKP_00153 1.2e-78 - - - S - - - Helix-turn-helix domain
NNGKMAKP_00154 8.86e-277 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NNGKMAKP_00155 5.37e-237 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NNGKMAKP_00156 2.2e-264 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NNGKMAKP_00157 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NNGKMAKP_00158 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NNGKMAKP_00159 5.34e-135 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
NNGKMAKP_00160 2.99e-87 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNGKMAKP_00162 9.75e-103 - - - F - - - Hydrolase, nudix family
NNGKMAKP_00163 1.34e-73 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NNGKMAKP_00164 2.33e-87 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NNGKMAKP_00165 1.19e-11 - 2.3.1.178 - M ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 ko00000,ko00001,ko00002,ko01000 phosphinothricin N-acetyltransferase activity
NNGKMAKP_00166 2.09e-73 - - - M - - - GNAT acetyltransferase
NNGKMAKP_00167 8.63e-20 - - - - - - - -
NNGKMAKP_00169 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NNGKMAKP_00170 8.95e-50 - - - S - - - repeat protein
NNGKMAKP_00171 2.06e-129 pgm - - G - - - Phosphoglycerate mutase family
NNGKMAKP_00172 2.78e-87 - - - S - - - Psort location Cytoplasmic, score
NNGKMAKP_00173 8.94e-43 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NNGKMAKP_00174 1.56e-109 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NNGKMAKP_00175 1.28e-87 csm5 - - L ko:K19140 - ko00000,ko02048 RAMP superfamily
NNGKMAKP_00176 3.51e-81 - - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
NNGKMAKP_00177 2.7e-88 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
NNGKMAKP_00178 1.77e-36 - - - L ko:K19138 - ko00000,ko02048 Pfam:DUF310
NNGKMAKP_00179 2.75e-253 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
NNGKMAKP_00180 3.35e-42 - - - S - - - Pfam:DUF2276
NNGKMAKP_00181 9.78e-190 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
NNGKMAKP_00182 5.46e-256 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
NNGKMAKP_00183 1.42e-264 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NNGKMAKP_00184 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNGKMAKP_00185 1.38e-106 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NNGKMAKP_00186 1.37e-122 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNGKMAKP_00187 1.26e-170 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NNGKMAKP_00188 1.77e-33 yozE - - S - - - Belongs to the UPF0346 family
NNGKMAKP_00189 2.28e-68 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NNGKMAKP_00190 2.64e-100 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
NNGKMAKP_00192 2.15e-73 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NNGKMAKP_00193 7.86e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NNGKMAKP_00194 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_00195 2.46e-166 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NNGKMAKP_00196 4.56e-137 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NNGKMAKP_00197 2.69e-142 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNGKMAKP_00198 3.84e-87 - - - L - - - Phage integrase, N-terminal SAM-like domain
NNGKMAKP_00200 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NNGKMAKP_00201 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NNGKMAKP_00202 2.08e-148 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NNGKMAKP_00205 1.33e-127 - - - M - - - Glycosyltransferase like family 2
NNGKMAKP_00206 8.57e-107 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
NNGKMAKP_00207 4.01e-117 - - - M - - - transferase activity, transferring glycosyl groups
NNGKMAKP_00208 4.35e-160 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNGKMAKP_00209 2.1e-100 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NNGKMAKP_00210 3.11e-108 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NNGKMAKP_00211 5.71e-72 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
NNGKMAKP_00212 4.9e-300 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NNGKMAKP_00213 7.4e-180 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NNGKMAKP_00214 1.71e-46 ypmB - - S - - - Protein conserved in bacteria
NNGKMAKP_00215 1.06e-274 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NNGKMAKP_00216 6.38e-120 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NNGKMAKP_00217 3.59e-156 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NNGKMAKP_00218 3.26e-172 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NNGKMAKP_00219 4.98e-144 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NNGKMAKP_00220 2.94e-133 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NNGKMAKP_00221 1.24e-186 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NNGKMAKP_00222 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NNGKMAKP_00223 7.31e-63 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NNGKMAKP_00224 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NNGKMAKP_00225 8e-74 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NNGKMAKP_00226 6.94e-28 - - - - - - - -
NNGKMAKP_00228 7.39e-156 - - - K - - - LysR substrate binding domain
NNGKMAKP_00229 1.38e-242 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNGKMAKP_00230 3.68e-136 - - - S - - - Acyltransferase family
NNGKMAKP_00231 4.59e-201 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NNGKMAKP_00232 4.88e-292 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NNGKMAKP_00233 6.95e-96 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NNGKMAKP_00234 6.96e-175 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NNGKMAKP_00235 3.04e-283 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NNGKMAKP_00236 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNGKMAKP_00237 4.77e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNGKMAKP_00238 1.85e-40 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNGKMAKP_00239 8.62e-123 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NNGKMAKP_00240 7.34e-167 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NNGKMAKP_00241 3.35e-65 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NNGKMAKP_00242 3.53e-94 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NNGKMAKP_00243 2.86e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NNGKMAKP_00244 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NNGKMAKP_00245 2e-124 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NNGKMAKP_00246 2.92e-189 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NNGKMAKP_00247 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NNGKMAKP_00248 1.09e-187 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NNGKMAKP_00249 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NNGKMAKP_00250 6.09e-96 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NNGKMAKP_00251 3.42e-31 yktA - - S - - - Belongs to the UPF0223 family
NNGKMAKP_00252 1.82e-21 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
NNGKMAKP_00253 1.36e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NNGKMAKP_00254 1.41e-32 - - - - - - - -
NNGKMAKP_00255 1.47e-30 ykzG - - S - - - Belongs to the UPF0356 family
NNGKMAKP_00256 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNGKMAKP_00257 1.93e-315 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NNGKMAKP_00258 5.22e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NNGKMAKP_00259 4.78e-246 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NNGKMAKP_00260 9.71e-274 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NNGKMAKP_00261 0.000361 - - - S - - - Tetratricopeptide repeat
NNGKMAKP_00262 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNGKMAKP_00263 1.88e-147 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NNGKMAKP_00264 2.6e-53 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NNGKMAKP_00265 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NNGKMAKP_00266 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NNGKMAKP_00267 5.87e-249 - - - E ko:K03294 - ko00000 amino acid
NNGKMAKP_00268 2.19e-78 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NNGKMAKP_00269 2.25e-144 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NNGKMAKP_00270 7.55e-73 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NNGKMAKP_00271 1.99e-37 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NNGKMAKP_00272 1.32e-55 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NNGKMAKP_00273 9.04e-263 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NNGKMAKP_00274 2.15e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NNGKMAKP_00275 1.59e-187 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NNGKMAKP_00276 1.64e-298 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NNGKMAKP_00277 7.23e-130 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NNGKMAKP_00278 9.72e-35 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNGKMAKP_00279 6.56e-182 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NNGKMAKP_00280 2.02e-308 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NNGKMAKP_00281 2.1e-303 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NNGKMAKP_00282 7.35e-69 yloU - - S - - - Asp23 family, cell envelope-related function
NNGKMAKP_00283 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NNGKMAKP_00284 1.07e-73 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NNGKMAKP_00285 3.24e-144 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NNGKMAKP_00286 2.11e-240 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NNGKMAKP_00287 1.11e-115 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NNGKMAKP_00288 1.02e-191 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NNGKMAKP_00289 1.81e-176 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NNGKMAKP_00290 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNGKMAKP_00291 5.34e-153 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NNGKMAKP_00292 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NNGKMAKP_00293 8.34e-132 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NNGKMAKP_00294 1.09e-119 - - - M - - - Phosphotransferase enzyme family
NNGKMAKP_00295 4.89e-36 spxA 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NNGKMAKP_00296 2.21e-236 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NNGKMAKP_00297 1.34e-20 - - - S - - - Protein of unknown function (DUF2969)
NNGKMAKP_00298 2.29e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NNGKMAKP_00299 2.82e-214 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NNGKMAKP_00300 4.91e-261 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNGKMAKP_00301 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
NNGKMAKP_00302 6.22e-70 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NNGKMAKP_00303 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NNGKMAKP_00304 8.1e-182 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NNGKMAKP_00305 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NNGKMAKP_00306 2.82e-74 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNGKMAKP_00307 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NNGKMAKP_00308 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNGKMAKP_00309 2.33e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NNGKMAKP_00310 6.26e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NNGKMAKP_00311 4.69e-172 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NNGKMAKP_00312 3.73e-114 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NNGKMAKP_00313 1.04e-230 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NNGKMAKP_00314 1.41e-111 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NNGKMAKP_00315 8.5e-277 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
NNGKMAKP_00316 4.63e-141 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NNGKMAKP_00317 2.17e-140 ampC - - V - - - Beta-lactamase
NNGKMAKP_00318 7.43e-41 - - - - - - - -
NNGKMAKP_00319 7.44e-153 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_00320 2.86e-256 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNGKMAKP_00322 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NNGKMAKP_00323 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NNGKMAKP_00324 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NNGKMAKP_00325 3.65e-75 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NNGKMAKP_00326 1.51e-165 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NNGKMAKP_00327 1.83e-120 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NNGKMAKP_00328 3.33e-151 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NNGKMAKP_00329 6.33e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NNGKMAKP_00330 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NNGKMAKP_00331 4.38e-35 ylxQ - - J - - - ribosomal protein
NNGKMAKP_00332 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NNGKMAKP_00333 1.25e-216 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NNGKMAKP_00334 1.16e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NNGKMAKP_00335 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNGKMAKP_00336 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NNGKMAKP_00337 1.78e-196 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NNGKMAKP_00338 1.36e-132 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NNGKMAKP_00339 4.05e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NNGKMAKP_00340 8.26e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NNGKMAKP_00341 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NNGKMAKP_00342 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
NNGKMAKP_00343 4.04e-45 - 2.1.1.63 - H ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NNGKMAKP_00345 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NNGKMAKP_00346 1.3e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NNGKMAKP_00347 5.45e-258 ynbB - - P - - - aluminum resistance
NNGKMAKP_00348 2.13e-141 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NNGKMAKP_00349 6.17e-24 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NNGKMAKP_00350 2.92e-60 yqhL - - P - - - Rhodanese-like protein
NNGKMAKP_00351 8.22e-203 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NNGKMAKP_00352 2.47e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NNGKMAKP_00353 3.18e-90 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
NNGKMAKP_00354 5.52e-51 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NNGKMAKP_00355 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NNGKMAKP_00357 1.97e-87 yciQ - - P - - - membrane protein (DUF2207)
NNGKMAKP_00358 2.16e-58 - - - S - - - mazG nucleotide pyrophosphohydrolase
NNGKMAKP_00359 1.38e-119 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NNGKMAKP_00360 3.98e-36 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NNGKMAKP_00361 7.41e-41 ynzC - - S - - - UPF0291 protein
NNGKMAKP_00362 1.29e-106 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NNGKMAKP_00363 1.27e-232 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NNGKMAKP_00364 5.91e-65 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NNGKMAKP_00365 3.13e-154 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NNGKMAKP_00366 4.39e-104 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NNGKMAKP_00367 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNGKMAKP_00368 5.71e-182 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNGKMAKP_00369 3.14e-131 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NNGKMAKP_00370 5.06e-47 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NNGKMAKP_00371 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NNGKMAKP_00372 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNGKMAKP_00373 2.93e-48 - - - S - - - Protein conserved in bacteria
NNGKMAKP_00374 1.14e-147 - - - - - - - -
NNGKMAKP_00375 4.27e-143 - - - - - - - -
NNGKMAKP_00376 1.01e-171 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NNGKMAKP_00377 1.6e-24 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NNGKMAKP_00378 1.19e-151 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNGKMAKP_00379 4.41e-218 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKMAKP_00380 1.46e-141 csrR - - K - - - response regulator
NNGKMAKP_00382 1.93e-127 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NNGKMAKP_00383 3.59e-285 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NNGKMAKP_00384 1.28e-199 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NNGKMAKP_00385 1.33e-75 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NNGKMAKP_00386 4.68e-119 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
NNGKMAKP_00387 1.82e-49 - - - - - - - -
NNGKMAKP_00388 1.52e-148 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
NNGKMAKP_00389 2.14e-28 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NNGKMAKP_00391 9.69e-14 - - - S - - - Domain of unknown function (DUF2479)
NNGKMAKP_00395 0.0 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
NNGKMAKP_00396 2e-182 - - - S - - - Phage tail protein
NNGKMAKP_00397 0.0 - - - L - - - Phage tail tape measure protein TP901
NNGKMAKP_00399 4.74e-75 - - - S - - - Phage tail assembly chaperone proteins, TAC
NNGKMAKP_00400 8.98e-158 - - - S - - - Phage tail tube protein
NNGKMAKP_00401 1.77e-85 - - - S - - - Protein of unknown function (DUF806)
NNGKMAKP_00402 1.95e-85 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NNGKMAKP_00403 3.15e-78 - - - S - - - Phage head-tail joining protein
NNGKMAKP_00404 3.09e-29 - - - S - - - Phage gp6-like head-tail connector protein
NNGKMAKP_00405 7.81e-282 - - - S - - - Phage capsid family
NNGKMAKP_00406 3.61e-153 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
NNGKMAKP_00407 4.42e-271 - - - S - - - Phage portal protein
NNGKMAKP_00409 0.0 - - - S - - - Phage Terminase
NNGKMAKP_00410 1.05e-107 - - - L - - - Phage terminase, small subunit
NNGKMAKP_00411 3.26e-98 - - - L - - - HNH nucleases
NNGKMAKP_00416 3.87e-74 - - - - - - - -
NNGKMAKP_00417 2.63e-63 - - - S - - - Protein of unknown function (DUF4065)
NNGKMAKP_00418 2.09e-41 - - - S - - - Phage transcriptional regulator, ArpU family
NNGKMAKP_00424 5.62e-59 - - - S - - - magnesium ion binding
NNGKMAKP_00425 0.0 - - - L - - - Primase C terminal 2 (PriCT-2)
NNGKMAKP_00426 0.0 - - - L - - - Helicase C-terminal domain protein
NNGKMAKP_00427 7.32e-103 - - - - - - - -
NNGKMAKP_00428 1.33e-51 - - - - - - - -
NNGKMAKP_00429 1.32e-65 - - - - - - - -
NNGKMAKP_00430 1.59e-132 - - - S - - - AAA domain
NNGKMAKP_00431 1.25e-206 - - - D - - - AAA domain
NNGKMAKP_00437 4.36e-34 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
NNGKMAKP_00439 4.52e-37 - - - K - - - Helix-turn-helix XRE-family like proteins
NNGKMAKP_00443 2.22e-96 - - - - - - - -
NNGKMAKP_00445 7.92e-31 - - - - - - - -
NNGKMAKP_00446 2.39e-42 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
NNGKMAKP_00447 3.33e-98 - - - L - - - Belongs to the 'phage' integrase family
NNGKMAKP_00448 7.31e-164 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NNGKMAKP_00449 4.91e-172 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NNGKMAKP_00450 6.9e-37 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NNGKMAKP_00451 4.86e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NNGKMAKP_00452 2.01e-113 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NNGKMAKP_00453 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NNGKMAKP_00454 1.58e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NNGKMAKP_00455 1.62e-153 ylbM - - S - - - Belongs to the UPF0348 family
NNGKMAKP_00456 3.23e-104 - - - H - - - Nodulation protein S (NodS)
NNGKMAKP_00457 3.39e-66 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NNGKMAKP_00458 5.96e-92 yqeK - - H - - - Hydrolase, HD family
NNGKMAKP_00459 7.07e-99 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NNGKMAKP_00460 4.74e-41 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NNGKMAKP_00461 1.19e-228 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NNGKMAKP_00462 3.33e-91 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NNGKMAKP_00463 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NNGKMAKP_00464 4.44e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NNGKMAKP_00465 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NNGKMAKP_00466 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNGKMAKP_00467 4.01e-137 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NNGKMAKP_00468 3.48e-95 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NNGKMAKP_00469 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NNGKMAKP_00470 3.05e-62 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NNGKMAKP_00471 8.5e-137 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NNGKMAKP_00472 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NNGKMAKP_00473 5.74e-88 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NNGKMAKP_00474 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
NNGKMAKP_00475 1.24e-282 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NNGKMAKP_00476 4.42e-297 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NNGKMAKP_00477 6.12e-98 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNGKMAKP_00478 2.95e-59 ytpP - - CO - - - Thioredoxin
NNGKMAKP_00480 8.2e-131 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NNGKMAKP_00481 3.39e-125 ytmP - - M - - - Choline/ethanolamine kinase
NNGKMAKP_00482 2e-88 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NNGKMAKP_00483 2.01e-122 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_00484 1.1e-68 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NNGKMAKP_00486 7.01e-144 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NNGKMAKP_00487 6.56e-163 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
NNGKMAKP_00488 2.92e-28 yheA - - S - - - Belongs to the UPF0342 family
NNGKMAKP_00489 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NNGKMAKP_00491 6.92e-117 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NNGKMAKP_00492 1.65e-223 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NNGKMAKP_00493 3.44e-92 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NNGKMAKP_00494 3.09e-59 ykuL - - S - - - CBS domain
NNGKMAKP_00495 1.05e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
NNGKMAKP_00496 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NNGKMAKP_00497 2.99e-160 - - - K - - - Transcriptional regulator
NNGKMAKP_00498 2.2e-105 - - - S - - - Domain of unknown function (DUF4865)
NNGKMAKP_00499 2.1e-305 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NNGKMAKP_00500 1.89e-291 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NNGKMAKP_00501 7.35e-140 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NNGKMAKP_00502 3e-130 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NNGKMAKP_00503 3.3e-160 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NNGKMAKP_00504 1.02e-274 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NNGKMAKP_00505 1.88e-83 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNGKMAKP_00506 1.16e-60 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NNGKMAKP_00507 1.74e-248 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNGKMAKP_00508 3.82e-126 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NNGKMAKP_00509 1.71e-130 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NNGKMAKP_00510 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNGKMAKP_00511 2.12e-129 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNGKMAKP_00512 1.29e-79 - - - K - - - Transcriptional regulator, MarR family
NNGKMAKP_00513 9.26e-87 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNGKMAKP_00514 5.97e-49 - - - - - - - -
NNGKMAKP_00516 0.0 - - - L - - - Type III restriction enzyme, res subunit
NNGKMAKP_00517 1.98e-86 - - - V - - - Type III restriction enzyme res subunit
NNGKMAKP_00518 2.3e-79 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
NNGKMAKP_00519 1.45e-240 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NNGKMAKP_00520 1.1e-104 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NNGKMAKP_00521 1.01e-77 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NNGKMAKP_00522 9.88e-244 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NNGKMAKP_00523 6.58e-245 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NNGKMAKP_00524 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NNGKMAKP_00525 5.21e-226 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NNGKMAKP_00529 5.57e-12 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
NNGKMAKP_00530 8.33e-13 - - - D - - - Antitoxin Phd_YefM, type II toxin-antitoxin system
NNGKMAKP_00531 2.96e-246 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
NNGKMAKP_00532 1.13e-83 ypsA - - S - - - Belongs to the UPF0398 family
NNGKMAKP_00533 3.75e-237 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NNGKMAKP_00534 8.23e-99 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NNGKMAKP_00535 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NNGKMAKP_00536 1.58e-143 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NNGKMAKP_00537 8.77e-159 yitL - - S ko:K00243 - ko00000 S1 domain
NNGKMAKP_00538 7.83e-56 - - - S - - - Protein of unknown function (DUF441)
NNGKMAKP_00539 8.84e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NNGKMAKP_00540 5.67e-128 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NNGKMAKP_00541 3.3e-80 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NNGKMAKP_00542 1.38e-75 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NNGKMAKP_00543 6.85e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNGKMAKP_00545 3.58e-10 - - - - - - - -
NNGKMAKP_00547 4.95e-274 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NNGKMAKP_00548 1.41e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NNGKMAKP_00549 3.63e-155 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NNGKMAKP_00550 1.56e-225 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NNGKMAKP_00551 1.18e-125 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NNGKMAKP_00552 3.17e-88 - - - - - - - -
NNGKMAKP_00555 1.51e-09 - - - M - - - LysM domain
NNGKMAKP_00556 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NNGKMAKP_00557 1.55e-37 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NNGKMAKP_00558 3.02e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NNGKMAKP_00565 1.1e-59 - - - H - - - Methyltransferase domain
NNGKMAKP_00566 5.1e-92 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NNGKMAKP_00567 3.19e-51 - - - M - - - Acetyltransferase (GNAT) family
NNGKMAKP_00569 1.51e-30 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
NNGKMAKP_00570 1.62e-51 ybbB - - S - - - Protein of unknown function (DUF1211)
NNGKMAKP_00573 3.99e-56 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
NNGKMAKP_00574 2.06e-42 - - - S - - - CHY zinc finger
NNGKMAKP_00575 3.61e-53 ywnA - - K - - - Transcriptional regulator
NNGKMAKP_00576 1.43e-105 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
NNGKMAKP_00577 5.66e-51 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Protease synthase and sporulation negative regulatory protein pai 1
NNGKMAKP_00578 2.78e-224 rsmF - - J - - - NOL1 NOP2 sun family protein
NNGKMAKP_00579 2.34e-81 - - - - - - - -
NNGKMAKP_00580 9.15e-105 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NNGKMAKP_00581 5.02e-144 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NNGKMAKP_00582 1.58e-77 yokL3 - - J - - - Acetyltransferase (GNAT) domain
NNGKMAKP_00583 3.28e-239 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NNGKMAKP_00584 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NNGKMAKP_00585 2.63e-265 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NNGKMAKP_00587 7.32e-58 - - - K - - - helix_turn_helix, arabinose operon control protein
NNGKMAKP_00588 9.59e-70 - - - S - - - Membrane
NNGKMAKP_00589 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NNGKMAKP_00590 0.0 - - - L - - - Helicase C-terminal domain protein
NNGKMAKP_00591 8.4e-66 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NNGKMAKP_00592 8.48e-37 - - - T - - - Putative diguanylate phosphodiesterase
NNGKMAKP_00593 4.61e-153 - - - T - - - diguanylate cyclase activity
NNGKMAKP_00594 0.0 - - - S - - - Bacterial cellulose synthase subunit
NNGKMAKP_00595 4.71e-253 ydaM - - M - - - Glycosyl transferase family group 2
NNGKMAKP_00596 8.54e-256 - - - S - - - Protein conserved in bacteria
NNGKMAKP_00597 6.26e-236 - - - - - - - -
NNGKMAKP_00598 3.92e-163 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NNGKMAKP_00599 3.67e-48 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
NNGKMAKP_00600 1.59e-184 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
NNGKMAKP_00601 3.58e-196 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NNGKMAKP_00602 4.03e-133 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NNGKMAKP_00603 4.59e-121 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NNGKMAKP_00604 4.26e-277 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
NNGKMAKP_00605 5.44e-254 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NNGKMAKP_00606 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NNGKMAKP_00607 1.06e-243 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NNGKMAKP_00608 8.1e-204 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NNGKMAKP_00609 8.48e-48 - - - M - - - LysM domain
NNGKMAKP_00610 5.6e-25 - - - P - - - Rhodanese Homology Domain
NNGKMAKP_00611 2.83e-66 - - - M - - - LysM domain protein
NNGKMAKP_00612 3.91e-116 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NNGKMAKP_00613 2.12e-108 - - - C - - - Domain of unknown function (DUF4931)
NNGKMAKP_00615 2.84e-91 - - - O - - - ADP-ribosylglycohydrolase
NNGKMAKP_00616 2.6e-130 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNGKMAKP_00617 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NNGKMAKP_00618 2.28e-91 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NNGKMAKP_00619 4.01e-104 ylmH - - S - - - S4 domain protein
NNGKMAKP_00620 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
NNGKMAKP_00621 8.14e-43 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NNGKMAKP_00622 4.52e-229 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NNGKMAKP_00623 2.46e-239 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NNGKMAKP_00624 2.27e-76 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NNGKMAKP_00625 4.28e-195 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NNGKMAKP_00626 2.09e-233 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NNGKMAKP_00627 3.64e-172 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NNGKMAKP_00628 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NNGKMAKP_00629 2.83e-13 ftsL - - D - - - Essential cell division protein
NNGKMAKP_00630 1.82e-180 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NNGKMAKP_00631 2.65e-82 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NNGKMAKP_00633 5.43e-196 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
NNGKMAKP_00634 1.16e-05 - - - S - - - Protein of unknown function (DUF4044)
NNGKMAKP_00635 6.26e-123 ybcH - - D ko:K06889 - ko00000 Alpha beta
NNGKMAKP_00636 6.52e-138 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NNGKMAKP_00637 2.01e-115 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_00638 3.02e-122 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NNGKMAKP_00639 7.95e-163 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NNGKMAKP_00640 4.14e-97 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NNGKMAKP_00641 9.34e-71 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NNGKMAKP_00642 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NNGKMAKP_00643 2.35e-207 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NNGKMAKP_00644 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
NNGKMAKP_00645 2.27e-102 radC - - L ko:K03630 - ko00000 DNA repair protein
NNGKMAKP_00646 1.21e-169 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NNGKMAKP_00647 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NNGKMAKP_00648 1.44e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NNGKMAKP_00649 1.2e-205 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NNGKMAKP_00650 6.54e-223 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NNGKMAKP_00651 1.56e-73 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NNGKMAKP_00652 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NNGKMAKP_00653 1.3e-30 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NNGKMAKP_00654 2.71e-246 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NNGKMAKP_00656 6.35e-97 uspA - - T - - - universal stress protein
NNGKMAKP_00657 8.41e-70 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NNGKMAKP_00658 5.17e-253 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NNGKMAKP_00659 1.39e-156 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NNGKMAKP_00661 4.19e-96 yviA - - S - - - Protein of unknown function (DUF421)
NNGKMAKP_00662 1.53e-17 - - - S - - - Protein of unknown function (DUF3290)
NNGKMAKP_00663 3e-08 - - - S - - - Protein of unknown function (DUF3290)
NNGKMAKP_00664 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NNGKMAKP_00665 0.0 - - - S - - - membrane
NNGKMAKP_00666 3.03e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NNGKMAKP_00667 2.68e-265 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NNGKMAKP_00668 1.18e-128 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
NNGKMAKP_00669 3.04e-179 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NNGKMAKP_00671 1.68e-22 - - - - - - - -
NNGKMAKP_00672 7.25e-255 oatA - - I - - - Acyltransferase
NNGKMAKP_00673 1.65e-272 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NNGKMAKP_00674 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NNGKMAKP_00675 4.92e-178 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNGKMAKP_00678 1.2e-51 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NNGKMAKP_00679 5.13e-93 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NNGKMAKP_00680 3.55e-79 yslB - - S - - - Protein of unknown function (DUF2507)
NNGKMAKP_00681 5.23e-54 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NNGKMAKP_00682 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NNGKMAKP_00683 7.68e-20 cvpA - - S - - - Colicin V production protein
NNGKMAKP_00684 3.67e-17 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NNGKMAKP_00685 4.23e-44 yrzB - - S - - - Belongs to the UPF0473 family
NNGKMAKP_00686 3.16e-78 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NNGKMAKP_00687 2.44e-49 yrzL - - S - - - Belongs to the UPF0297 family
NNGKMAKP_00688 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NNGKMAKP_00689 5.24e-237 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NNGKMAKP_00690 5.35e-155 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NNGKMAKP_00691 3.5e-18 - - - - - - - -
NNGKMAKP_00692 9.65e-185 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNGKMAKP_00693 4.44e-85 lutC - - S ko:K00782 - ko00000 LUD domain
NNGKMAKP_00694 4.72e-309 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
NNGKMAKP_00695 3.54e-150 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
NNGKMAKP_00696 1.68e-263 - - - E ko:K03294 - ko00000 Amino Acid
NNGKMAKP_00698 3.61e-79 uspA3 - - T - - - universal stress protein
NNGKMAKP_00700 3.02e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
NNGKMAKP_00701 1.46e-263 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NNGKMAKP_00702 2.88e-231 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NNGKMAKP_00703 1.45e-193 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NNGKMAKP_00704 2.19e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NNGKMAKP_00705 5.7e-287 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NNGKMAKP_00706 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NNGKMAKP_00707 4.38e-256 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NNGKMAKP_00708 1.84e-203 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NNGKMAKP_00709 2.09e-111 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NNGKMAKP_00710 1.06e-84 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NNGKMAKP_00711 1.49e-115 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NNGKMAKP_00712 7.96e-186 ymfH - - S - - - Peptidase M16
NNGKMAKP_00713 2.97e-136 ymfF - - S - - - Peptidase M16 inactive domain protein
NNGKMAKP_00714 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NNGKMAKP_00715 2.62e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NNGKMAKP_00716 7.09e-125 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NNGKMAKP_00717 1.44e-83 - - - J ko:K03976 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
NNGKMAKP_00718 1.61e-207 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNGKMAKP_00719 4.23e-251 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNGKMAKP_00720 4e-24 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NNGKMAKP_00721 9.78e-167 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NNGKMAKP_00722 1.59e-38 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NNGKMAKP_00723 1.1e-284 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NNGKMAKP_00724 2.27e-87 ybbR - - S - - - YbbR-like protein
NNGKMAKP_00725 4.8e-163 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNGKMAKP_00726 5.56e-92 - - - S - - - Protein of unknown function (DUF1361)
NNGKMAKP_00727 3.49e-145 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NNGKMAKP_00728 9.58e-90 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NNGKMAKP_00729 1e-72 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NNGKMAKP_00730 5.74e-180 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NNGKMAKP_00731 1.52e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NNGKMAKP_00732 1.68e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNGKMAKP_00733 5.54e-53 - - - - - - - -
NNGKMAKP_00734 4.3e-91 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NNGKMAKP_00735 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NNGKMAKP_00736 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NNGKMAKP_00737 6.32e-224 eriC - - P ko:K03281 - ko00000 chloride
NNGKMAKP_00738 5.39e-189 - - - E - - - Major Facilitator Superfamily
NNGKMAKP_00739 8.04e-212 yclK - - T - - - Histidine kinase
NNGKMAKP_00740 1.95e-134 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NNGKMAKP_00741 4.06e-167 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNGKMAKP_00742 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NNGKMAKP_00743 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NNGKMAKP_00744 1.99e-264 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NNGKMAKP_00745 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNGKMAKP_00746 7.89e-175 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NNGKMAKP_00748 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NNGKMAKP_00749 2.05e-191 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NNGKMAKP_00750 9.55e-197 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NNGKMAKP_00751 6.89e-161 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NNGKMAKP_00752 4.6e-101 - - - GM - - - NAD dependent epimerase dehydratase family protein
NNGKMAKP_00753 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NNGKMAKP_00754 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NNGKMAKP_00755 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NNGKMAKP_00756 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NNGKMAKP_00757 5.84e-143 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NNGKMAKP_00758 1.76e-169 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NNGKMAKP_00759 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NNGKMAKP_00760 1.02e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NNGKMAKP_00761 1.72e-104 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKMAKP_00762 1.03e-110 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NNGKMAKP_00763 7e-81 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
NNGKMAKP_00764 4.56e-207 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NNGKMAKP_00765 1.71e-139 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNGKMAKP_00766 7.85e-119 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
NNGKMAKP_00767 7.08e-105 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NNGKMAKP_00768 4.87e-65 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NNGKMAKP_00769 2.14e-159 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NNGKMAKP_00770 3.75e-200 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NNGKMAKP_00771 0.0 ydaO - - E - - - amino acid
NNGKMAKP_00772 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
NNGKMAKP_00773 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NNGKMAKP_00774 1.7e-46 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NNGKMAKP_00775 7.13e-42 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNGKMAKP_00776 1.52e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NNGKMAKP_00777 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NNGKMAKP_00778 5.06e-206 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NNGKMAKP_00779 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NNGKMAKP_00780 5.25e-88 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NNGKMAKP_00781 8.09e-178 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NNGKMAKP_00782 9.93e-104 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NNGKMAKP_00783 5.19e-133 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NNGKMAKP_00784 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
NNGKMAKP_00785 5.52e-104 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NNGKMAKP_00786 1.78e-82 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NNGKMAKP_00787 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NNGKMAKP_00788 3.64e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NNGKMAKP_00789 4.7e-269 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNGKMAKP_00790 1.11e-80 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NNGKMAKP_00791 2.25e-96 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NNGKMAKP_00792 1.36e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NNGKMAKP_00793 1.81e-58 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NNGKMAKP_00794 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNGKMAKP_00795 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNGKMAKP_00796 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNGKMAKP_00797 4.43e-72 - - - - - - - -
NNGKMAKP_00798 2.18e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NNGKMAKP_00799 1.1e-97 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NNGKMAKP_00800 9.98e-150 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NNGKMAKP_00801 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NNGKMAKP_00802 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NNGKMAKP_00803 3.08e-16 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NNGKMAKP_00804 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NNGKMAKP_00805 2.29e-139 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNGKMAKP_00806 3.45e-73 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NNGKMAKP_00807 3.21e-263 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NNGKMAKP_00808 7.38e-313 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NNGKMAKP_00809 1.38e-195 yacL - - S - - - domain protein
NNGKMAKP_00810 2.79e-284 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NNGKMAKP_00811 4.81e-95 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NNGKMAKP_00812 1.17e-25 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NNGKMAKP_00813 4.25e-280 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NNGKMAKP_00814 2.56e-45 - - - S - - - Enterocin A Immunity
NNGKMAKP_00815 4.1e-109 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NNGKMAKP_00816 2.13e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NNGKMAKP_00817 5.35e-148 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNGKMAKP_00819 1.32e-53 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NNGKMAKP_00820 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NNGKMAKP_00821 3.23e-166 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NNGKMAKP_00822 1.79e-306 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NNGKMAKP_00823 3.32e-113 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NNGKMAKP_00824 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NNGKMAKP_00825 1.22e-114 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNGKMAKP_00828 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NNGKMAKP_00829 5.69e-120 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NNGKMAKP_00830 2.24e-16 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
NNGKMAKP_00831 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NNGKMAKP_00832 3.03e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NNGKMAKP_00833 2.18e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
NNGKMAKP_00834 5.64e-69 gtcA - - S - - - Teichoic acid glycosylation protein
NNGKMAKP_00835 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NNGKMAKP_00836 5.65e-151 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
NNGKMAKP_00837 1.07e-153 - - - S - - - Sulfite exporter TauE/SafE
NNGKMAKP_00838 1.21e-90 - - - K - - - Sugar-specific transcriptional regulator TrmB
NNGKMAKP_00839 9.53e-214 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NNGKMAKP_00840 2.12e-230 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
NNGKMAKP_00841 0.0 - - - E - - - Amino acid permease
NNGKMAKP_00842 1.29e-109 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NNGKMAKP_00843 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NNGKMAKP_00844 1.09e-94 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NNGKMAKP_00845 2.12e-271 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
NNGKMAKP_00846 3.8e-125 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NNGKMAKP_00847 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NNGKMAKP_00850 2.29e-200 yfmL - - L - - - DEAD DEAH box helicase
NNGKMAKP_00851 1.32e-161 mocA - - S - - - Oxidoreductase
NNGKMAKP_00852 1.13e-32 - - - S - - - Domain of unknown function (DUF4828)
NNGKMAKP_00853 9.89e-215 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NNGKMAKP_00854 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NNGKMAKP_00855 4.49e-244 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NNGKMAKP_00856 1.37e-157 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NNGKMAKP_00857 8.3e-210 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NNGKMAKP_00858 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NNGKMAKP_00859 8.86e-274 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NNGKMAKP_00860 5.51e-45 - - - O - - - ADP-ribosylglycohydrolase
NNGKMAKP_00861 6.89e-276 gdhA 1.4.1.3, 1.4.1.4 - E ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NNGKMAKP_00862 9.71e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NNGKMAKP_00863 5.31e-41 - - - K - - - GNAT family
NNGKMAKP_00864 1.38e-54 - - - - - - - -
NNGKMAKP_00866 9.52e-238 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NNGKMAKP_00867 1.83e-118 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNGKMAKP_00868 1.79e-148 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNGKMAKP_00869 5.56e-124 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NNGKMAKP_00870 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NNGKMAKP_00871 2.73e-59 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NNGKMAKP_00872 1.56e-254 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NNGKMAKP_00873 5.57e-96 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NNGKMAKP_00874 2.1e-76 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NNGKMAKP_00875 5.7e-82 - - - S - - - ECF transporter, substrate-specific component
NNGKMAKP_00876 2.15e-162 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NNGKMAKP_00877 7.17e-315 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NNGKMAKP_00878 7.18e-91 mleR - - K - - - LysR family
NNGKMAKP_00879 1.81e-74 napB - - K - - - transcriptional
NNGKMAKP_00880 1.17e-52 - - - K - - - Bacterial regulatory proteins, tetR family
NNGKMAKP_00881 2.3e-78 usp2 - - T - - - Belongs to the universal stress protein A family
NNGKMAKP_00882 2.15e-59 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NNGKMAKP_00883 4.28e-15 - - - M - - - Rib/alpha-like repeat
NNGKMAKP_00885 7.25e-31 - - - M - - - Rib/alpha-like repeat
NNGKMAKP_00886 1.95e-131 ypuA - - S - - - Protein of unknown function (DUF1002)
NNGKMAKP_00887 4.73e-79 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
NNGKMAKP_00888 1.32e-204 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNGKMAKP_00889 1.43e-48 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NNGKMAKP_00890 3.63e-267 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NNGKMAKP_00891 1.38e-249 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NNGKMAKP_00892 1.07e-301 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NNGKMAKP_00893 2.77e-19 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
NNGKMAKP_00894 2.47e-222 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
NNGKMAKP_00895 1.72e-75 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NNGKMAKP_00896 1.22e-121 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NNGKMAKP_00897 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NNGKMAKP_00898 1.25e-92 ywlG - - S - - - Belongs to the UPF0340 family
NNGKMAKP_00899 1.94e-113 - - - C - - - Oxidoreductase
NNGKMAKP_00900 1.72e-83 - - - C - - - Oxidoreductase
NNGKMAKP_00901 9.95e-209 spoVK - - O - - - stage V sporulation protein K
NNGKMAKP_00902 3.79e-94 - - - S - - - Domain of unknown function (DUF3841)
NNGKMAKP_00903 1.22e-74 - - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
NNGKMAKP_00904 9.32e-108 - - - S - - - Domain of unknown function (DUF4343)
NNGKMAKP_00905 2.91e-07 - - - - - - - -
NNGKMAKP_00906 5.1e-114 - - - S - - - AIPR protein
NNGKMAKP_00907 9.91e-91 - - - S - - - PFAM acyltransferase 3
NNGKMAKP_00909 0.0 - - - S - - - Protein of unknown function DUF262
NNGKMAKP_00910 0.0 - - - L - - - Type III restriction enzyme, res subunit
NNGKMAKP_00911 7.98e-154 - - - L - - - Eco57I restriction-modification methylase
NNGKMAKP_00912 7.8e-92 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
NNGKMAKP_00913 6.92e-27 - - - K - - - Cro/C1-type HTH DNA-binding domain
NNGKMAKP_00914 2.27e-166 - - - - - - - -
NNGKMAKP_00915 5.03e-07 - - - - - - - -
NNGKMAKP_00916 1.04e-102 - - - - - - - -
NNGKMAKP_00918 3.2e-12 - - - - - - - -
NNGKMAKP_00919 8.91e-15 - - - - - - - -
NNGKMAKP_00920 4.54e-223 - - - L - - - Protein of unknown function (DUF2800)
NNGKMAKP_00921 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase
NNGKMAKP_00922 8.88e-52 - - - S - - - Psort location Cytoplasmic, score
NNGKMAKP_00923 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
NNGKMAKP_00924 1.36e-42 - - - S - - - VRR_NUC
NNGKMAKP_00925 1.46e-248 - - - L - - - SNF2 family N-terminal domain
NNGKMAKP_00926 3.78e-65 - - - - - - - -
NNGKMAKP_00927 4.69e-72 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH nucleases
NNGKMAKP_00928 3.8e-118 - - - - - - - -
NNGKMAKP_00929 4.36e-254 - - - KL - - - DNA methylase
NNGKMAKP_00930 1.3e-69 - - - S - - - Psort location Cytoplasmic, score
NNGKMAKP_00931 7.25e-34 - - - S - - - Domain of unknown function (DUF5049)
NNGKMAKP_00932 0.0 - - - S - - - overlaps another CDS with the same product name
NNGKMAKP_00933 1.01e-253 - - - S - - - Phage portal protein
NNGKMAKP_00934 2.35e-100 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
NNGKMAKP_00935 9.69e-215 - - - S - - - Phage capsid family
NNGKMAKP_00936 2.74e-42 - - - S - - - Phage gp6-like head-tail connector protein
NNGKMAKP_00937 3.47e-61 - - - S - - - Phage head-tail joining protein
NNGKMAKP_00938 1.36e-66 - - - S - - - Bacteriophage holin family
NNGKMAKP_00939 1.12e-10 - - - - - - - -
NNGKMAKP_00940 2.33e-144 - - - L - - - Recombinase zinc beta ribbon domain
NNGKMAKP_00941 7.98e-09 - - - L ko:K06400 - ko00000 Psort location Cytoplasmic, score
NNGKMAKP_00942 1.03e-243 - - - L ko:K06400 - ko00000 Recombinase
NNGKMAKP_00943 2.43e-269 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNGKMAKP_00944 5.09e-183 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NNGKMAKP_00945 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNGKMAKP_00946 2.07e-294 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NNGKMAKP_00947 1.34e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNGKMAKP_00948 1.2e-205 camS - - S - - - sex pheromone
NNGKMAKP_00949 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NNGKMAKP_00950 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NNGKMAKP_00952 1.5e-182 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NNGKMAKP_00957 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NNGKMAKP_00958 2.4e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNGKMAKP_00959 4.6e-167 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NNGKMAKP_00960 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NNGKMAKP_00961 3.54e-100 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NNGKMAKP_00962 2.59e-117 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NNGKMAKP_00963 8.69e-63 yabR - - J ko:K07571 - ko00000 RNA binding
NNGKMAKP_00964 3.7e-29 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NNGKMAKP_00965 1.1e-42 yabO - - J - - - S4 domain protein
NNGKMAKP_00966 1.88e-172 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NNGKMAKP_00967 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NNGKMAKP_00968 1.45e-95 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NNGKMAKP_00969 8.16e-202 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NNGKMAKP_00970 2.2e-110 - - - S - - - (CBS) domain
NNGKMAKP_00971 4.44e-180 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNGKMAKP_00972 8.24e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NNGKMAKP_00973 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NNGKMAKP_00974 8.18e-73 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NNGKMAKP_00975 5.46e-126 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NNGKMAKP_00976 7.16e-143 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NNGKMAKP_00977 1.13e-188 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNGKMAKP_00979 5.12e-67 - - - M - - - LysM domain protein
NNGKMAKP_00980 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NNGKMAKP_00981 1.84e-110 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NNGKMAKP_00982 1.48e-41 - - - K - - - transcriptional regulator (TetR family)
NNGKMAKP_00983 2.3e-139 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NNGKMAKP_00984 3.65e-110 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_00985 1.26e-86 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NNGKMAKP_00986 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNGKMAKP_00987 4e-307 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NNGKMAKP_00989 3.79e-07 - - - - - - - -
NNGKMAKP_00990 2.29e-79 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NNGKMAKP_00991 1.04e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NNGKMAKP_00992 6.22e-160 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NNGKMAKP_00993 3.1e-138 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNGKMAKP_00994 1.29e-139 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNGKMAKP_00995 2.27e-127 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNGKMAKP_00996 4.47e-71 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NNGKMAKP_00997 1.93e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNGKMAKP_00998 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NNGKMAKP_00999 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NNGKMAKP_01000 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NNGKMAKP_01001 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NNGKMAKP_01002 7.34e-142 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NNGKMAKP_01003 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NNGKMAKP_01004 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NNGKMAKP_01005 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NNGKMAKP_01006 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NNGKMAKP_01007 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NNGKMAKP_01008 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NNGKMAKP_01009 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NNGKMAKP_01010 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNGKMAKP_01011 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NNGKMAKP_01012 3.84e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NNGKMAKP_01013 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NNGKMAKP_01014 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NNGKMAKP_01015 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NNGKMAKP_01016 8.95e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NNGKMAKP_01017 1.62e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NNGKMAKP_01018 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NNGKMAKP_01019 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NNGKMAKP_01020 4.58e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NNGKMAKP_01021 1.34e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NNGKMAKP_01022 6.55e-130 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NNGKMAKP_01023 2.82e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NNGKMAKP_01024 3.24e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NNGKMAKP_01025 1.21e-217 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NNGKMAKP_01026 1.07e-100 - - - K - - - rpiR family
NNGKMAKP_01027 6.58e-68 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NNGKMAKP_01028 7.94e-186 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NNGKMAKP_01029 2.79e-14 - - - K - - - Acetyltransferase (GNAT) domain
NNGKMAKP_01030 1.17e-239 steT - - E ko:K03294 - ko00000 amino acid
NNGKMAKP_01031 3.11e-65 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NNGKMAKP_01032 5.27e-80 - - - S - - - Protein of unknown function (DUF1211)
NNGKMAKP_01033 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NNGKMAKP_01034 3.98e-308 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NNGKMAKP_01035 3.94e-22 yneR - - - - - - -
NNGKMAKP_01036 3.57e-290 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NNGKMAKP_01037 6.19e-283 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
NNGKMAKP_01038 9.5e-136 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NNGKMAKP_01039 5.22e-192 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NNGKMAKP_01040 4.15e-12 yobS - - K - - - Bacterial regulatory proteins, tetR family
NNGKMAKP_01041 8.94e-141 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NNGKMAKP_01042 7.54e-212 - - - S - - - Putative threonine/serine exporter
NNGKMAKP_01043 1.26e-89 - - - J - - - Acetyltransferase (GNAT) domain
NNGKMAKP_01044 7.69e-120 yicL - - EG - - - EamA-like transporter family
NNGKMAKP_01045 3.2e-278 pepF - - E - - - Oligopeptidase F
NNGKMAKP_01046 2.89e-137 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NNGKMAKP_01047 4.24e-226 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NNGKMAKP_01049 2.3e-175 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
NNGKMAKP_01050 1.45e-80 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NNGKMAKP_01051 3.06e-32 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NNGKMAKP_01052 2.61e-217 - - - S - - - Putative peptidoglycan binding domain
NNGKMAKP_01053 2.33e-41 - - - K - - - Transcriptional regulator, MarR family
NNGKMAKP_01054 4.36e-269 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_01055 1.67e-288 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
NNGKMAKP_01056 4.16e-212 - - - EGP - - - Mycoplasma MFS transporter
NNGKMAKP_01057 2.31e-198 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 FMN-dependent dehydrogenase
NNGKMAKP_01058 1.74e-136 yxeH - - S - - - hydrolase
NNGKMAKP_01059 2.43e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NNGKMAKP_01060 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKMAKP_01061 5.35e-126 yycH - - S - - - YycH protein
NNGKMAKP_01062 3.35e-100 yycI - - S - - - YycH protein
NNGKMAKP_01063 2.49e-43 - - - S - - - YjbR
NNGKMAKP_01064 1.46e-147 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NNGKMAKP_01065 1.37e-188 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NNGKMAKP_01066 1.36e-94 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NNGKMAKP_01067 4.21e-69 - - - GM - - - NAD(P)H-binding
NNGKMAKP_01068 3.67e-34 - - - K - - - MarR family transcriptional regulator
NNGKMAKP_01069 3.13e-111 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NNGKMAKP_01070 1.46e-61 - - - S - - - PD-(D/E)XK nuclease family transposase
NNGKMAKP_01072 2.43e-284 - - - L - - - Probable transposase
NNGKMAKP_01073 1.6e-261 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter
NNGKMAKP_01074 6.89e-175 - - - S - - - interspecies interaction between organisms
NNGKMAKP_01075 1.77e-105 - - - E - - - IrrE N-terminal-like domain
NNGKMAKP_01076 2.13e-12 - - - S - - - Domain of unknown function (DUF4411)
NNGKMAKP_01077 9.86e-64 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the accessory SecA2 SecY2 system specifically required for export of
NNGKMAKP_01078 8.98e-100 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
NNGKMAKP_01079 3.48e-123 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system protein Asp2
NNGKMAKP_01080 9.98e-19 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec system protein Asp3
NNGKMAKP_01081 4.57e-303 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNGKMAKP_01083 2.13e-39 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NNGKMAKP_01084 9.34e-105 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNGKMAKP_01085 1.15e-109 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNGKMAKP_01086 2.94e-127 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNGKMAKP_01087 2.45e-132 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_01088 1.32e-17 - - - - - - - -
NNGKMAKP_01089 9.05e-123 - - - - - - - -
NNGKMAKP_01090 1.06e-16 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
NNGKMAKP_01091 1e-68 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NNGKMAKP_01092 1.24e-268 yhdG - - E ko:K03294 - ko00000 Amino Acid
NNGKMAKP_01093 5.89e-316 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNGKMAKP_01094 0.0 - - - L - - - Helicase C-terminal domain protein
NNGKMAKP_01095 2.17e-102 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NNGKMAKP_01096 6.84e-232 yhdP - - S - - - Transporter associated domain
NNGKMAKP_01097 7.84e-33 - - - - - - - -
NNGKMAKP_01098 4.9e-95 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NNGKMAKP_01099 1.13e-162 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NNGKMAKP_01100 2.78e-126 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NNGKMAKP_01101 1.76e-93 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NNGKMAKP_01102 6.88e-200 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NNGKMAKP_01103 7.98e-174 - - - V - - - MatE
NNGKMAKP_01104 2.95e-58 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNGKMAKP_01105 1.18e-112 - - - S - - - Alpha beta hydrolase
NNGKMAKP_01106 3.71e-122 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NNGKMAKP_01107 1.1e-217 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NNGKMAKP_01108 3.06e-138 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
NNGKMAKP_01109 3.16e-131 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NNGKMAKP_01110 7.29e-46 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
NNGKMAKP_01111 1.09e-68 ccl - - S - - - QueT transporter
NNGKMAKP_01113 3.77e-83 - - - S - - - Uncharacterised protein, DegV family COG1307
NNGKMAKP_01114 1.36e-27 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNGKMAKP_01115 1.09e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNGKMAKP_01116 7.86e-46 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NNGKMAKP_01117 2.09e-110 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNGKMAKP_01118 3.94e-155 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NNGKMAKP_01119 3.42e-65 - - - S - - - Threonine/Serine exporter, ThrE
NNGKMAKP_01120 9.59e-104 - - - S - - - Putative threonine/serine exporter
NNGKMAKP_01121 5.59e-37 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NNGKMAKP_01122 2.51e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
NNGKMAKP_01123 2.17e-119 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNGKMAKP_01124 8.5e-29 - - - - - - - -
NNGKMAKP_01125 1.3e-74 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
NNGKMAKP_01126 1.55e-23 - - - - - - - -
NNGKMAKP_01127 1.72e-81 - - - I - - - alpha/beta hydrolase fold
NNGKMAKP_01128 2.61e-52 - - - S - - - branched-chain amino acid
NNGKMAKP_01129 1.78e-132 - - - E - - - AzlC protein
NNGKMAKP_01130 1.81e-24 - - - - - - - -
NNGKMAKP_01131 5.1e-163 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NNGKMAKP_01132 1.97e-149 yhgE - - V ko:K01421 - ko00000 domain protein
NNGKMAKP_01134 0.000331 - - - S - - - zinc-ribbon domain
NNGKMAKP_01135 8.68e-159 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NNGKMAKP_01136 1.34e-218 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NNGKMAKP_01137 3.2e-148 ydbI - - K - - - AI-2E family transporter
NNGKMAKP_01138 5.91e-76 - - - EG - - - EamA-like transporter family
NNGKMAKP_01139 1.51e-96 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
NNGKMAKP_01140 6.3e-147 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NNGKMAKP_01141 2.21e-86 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NNGKMAKP_01142 5.43e-209 - - - C - - - Luciferase-like monooxygenase
NNGKMAKP_01143 1.7e-55 hxlR - - K - - - Transcriptional regulator, HxlR family
NNGKMAKP_01144 6.68e-219 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NNGKMAKP_01145 5.28e-131 gntR - - K - - - UbiC transcription regulator-associated domain protein
NNGKMAKP_01146 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NNGKMAKP_01147 4.18e-107 pncA - - Q - - - isochorismatase
NNGKMAKP_01148 1.14e-81 pgm1 - - G - - - phosphoglycerate mutase
NNGKMAKP_01149 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKMAKP_01150 1.45e-109 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NNGKMAKP_01151 8.27e-316 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NNGKMAKP_01152 3.38e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NNGKMAKP_01154 3.58e-226 XK27_08315 - - M - - - Sulfatase
NNGKMAKP_01155 5.79e-67 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NNGKMAKP_01156 2.67e-112 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NNGKMAKP_01157 3.1e-215 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NNGKMAKP_01158 3.47e-160 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NNGKMAKP_01159 5.63e-221 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NNGKMAKP_01160 3e-107 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNGKMAKP_01161 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NNGKMAKP_01162 8.92e-75 - - - S - - - Psort location CytoplasmicMembrane, score
NNGKMAKP_01163 3.71e-194 XK27_08315 - - M - - - Sulfatase
NNGKMAKP_01164 5.28e-128 - - - S - - - Bacterial membrane protein, YfhO
NNGKMAKP_01165 3.29e-86 - - - S - - - Bacterial membrane protein, YfhO
NNGKMAKP_01166 4.55e-20 - - - - - - - -
NNGKMAKP_01167 2.23e-187 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
NNGKMAKP_01168 3.47e-66 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
NNGKMAKP_01169 3.39e-195 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NNGKMAKP_01170 8.69e-86 - - - S - - - NADPH-dependent FMN reductase
NNGKMAKP_01171 1.15e-120 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNGKMAKP_01172 7.97e-206 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NNGKMAKP_01173 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NNGKMAKP_01174 4.21e-47 - - - - - - - -
NNGKMAKP_01175 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NNGKMAKP_01176 1.84e-169 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NNGKMAKP_01177 1.34e-06 - - - E - - - lipolytic protein G-D-S-L family
NNGKMAKP_01178 3.91e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_01179 9.95e-241 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NNGKMAKP_01180 2.55e-268 potE - - E - - - Amino Acid
NNGKMAKP_01181 1.24e-43 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
NNGKMAKP_01182 1.72e-172 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
NNGKMAKP_01184 2.4e-81 - - - D - - - Peptidase family M23
NNGKMAKP_01185 1.42e-235 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NNGKMAKP_01186 3.48e-248 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NNGKMAKP_01187 3.8e-147 - - - M - - - Core-2/I-Branching enzyme
NNGKMAKP_01188 1.37e-117 - - - M - - - transferase activity, transferring glycosyl groups
NNGKMAKP_01189 2.53e-116 - - - M - - - transferase activity, transferring glycosyl groups
NNGKMAKP_01190 1.3e-81 - - - - - - - -
NNGKMAKP_01191 4.85e-115 epsE2 - - M - - - Bacterial sugar transferase
NNGKMAKP_01192 1.41e-163 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NNGKMAKP_01193 1.72e-141 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NNGKMAKP_01194 7.76e-118 ywqD - - D - - - Capsular exopolysaccharide family
NNGKMAKP_01195 7.01e-99 epsB - - M - - - biosynthesis protein
NNGKMAKP_01196 2.68e-119 - - - H - - - NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
NNGKMAKP_01197 1.42e-265 - - - E ko:K03294 - ko00000 Amino acid permease
NNGKMAKP_01198 1e-266 - - - M - - - MobA-like NTP transferase domain
NNGKMAKP_01199 2.71e-135 licC - - M - - - LicC protein
NNGKMAKP_01200 1.09e-40 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NNGKMAKP_01201 2.21e-111 cps2J - - S - - - Polysaccharide biosynthesis protein
NNGKMAKP_01202 1.18e-48 - - - M - - - -O-antigen
NNGKMAKP_01203 1.28e-92 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
NNGKMAKP_01204 5.19e-127 - - - M - - - Glycosyltransferase, group 1 family protein
NNGKMAKP_01205 1.26e-70 - - - S - - - Glycosyltransferase family 28 C-terminal domain
NNGKMAKP_01206 8.3e-86 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
NNGKMAKP_01207 2.35e-132 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
NNGKMAKP_01209 6.65e-163 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NNGKMAKP_01210 2.98e-212 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NNGKMAKP_01211 2.26e-130 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NNGKMAKP_01212 7.75e-181 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NNGKMAKP_01213 2.47e-128 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NNGKMAKP_01214 5.91e-124 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
NNGKMAKP_01215 2.29e-77 - - - S - - - Glycosyltransferase like family 2
NNGKMAKP_01216 5.74e-148 cps3J - - M - - - Domain of unknown function (DUF4422)
NNGKMAKP_01217 1.48e-46 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNGKMAKP_01218 2.62e-114 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NNGKMAKP_01219 2.95e-81 - - - S - - - Haloacid dehalogenase-like hydrolase
NNGKMAKP_01220 4.49e-192 - - - EGP - - - Major Facilitator
NNGKMAKP_01222 1.9e-88 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NNGKMAKP_01223 1.07e-34 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NNGKMAKP_01224 2.53e-112 - - - S - - - NADPH-dependent FMN reductase
NNGKMAKP_01225 1.42e-129 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NNGKMAKP_01226 1.98e-71 - - - S - - - ECF transporter, substrate-specific component
NNGKMAKP_01227 3.47e-138 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NNGKMAKP_01228 1.6e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NNGKMAKP_01229 5.14e-132 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NNGKMAKP_01230 6.49e-70 - - - V - - - Abi-like protein
NNGKMAKP_01231 3.87e-46 - - - - - - - -
NNGKMAKP_01232 1.1e-73 - - - S - - - Protein of unknown function (DUF1129)
NNGKMAKP_01233 4.17e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NNGKMAKP_01234 3.11e-33 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NNGKMAKP_01235 4.14e-138 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NNGKMAKP_01236 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NNGKMAKP_01237 8.74e-104 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NNGKMAKP_01238 3.62e-130 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NNGKMAKP_01239 6.73e-161 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NNGKMAKP_01240 1.4e-92 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
NNGKMAKP_01241 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NNGKMAKP_01242 6.54e-235 - - - L - - - Probable transposase
NNGKMAKP_01243 3.36e-79 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
NNGKMAKP_01244 1.22e-93 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NNGKMAKP_01246 5.09e-83 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NNGKMAKP_01247 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NNGKMAKP_01248 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NNGKMAKP_01249 5e-45 - - - - - - - -
NNGKMAKP_01250 7.93e-180 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNGKMAKP_01251 4.05e-197 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NNGKMAKP_01252 1.57e-123 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNGKMAKP_01253 2e-199 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NNGKMAKP_01254 9.51e-72 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNGKMAKP_01255 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
NNGKMAKP_01257 2.2e-121 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_01258 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
NNGKMAKP_01259 8.51e-236 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NNGKMAKP_01260 1.63e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNGKMAKP_01261 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NNGKMAKP_01262 6.4e-138 - - - P - - - Integral membrane protein TerC family
NNGKMAKP_01263 3.07e-48 - - - K - - - Transcriptional regulator
NNGKMAKP_01264 1.36e-121 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NNGKMAKP_01265 6.11e-130 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_01266 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNGKMAKP_01268 2.14e-18 - - - V - - - the current gene model (or a revised gene model) may contain a frame shift
NNGKMAKP_01269 7.14e-237 noxE - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NNGKMAKP_01270 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NNGKMAKP_01271 4.71e-259 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
NNGKMAKP_01272 9.35e-219 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NNGKMAKP_01273 3.08e-135 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NNGKMAKP_01274 1.7e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
NNGKMAKP_01275 1.4e-88 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
NNGKMAKP_01276 6.18e-192 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
NNGKMAKP_01277 5.15e-145 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
NNGKMAKP_01278 2.02e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
NNGKMAKP_01279 8.29e-264 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NNGKMAKP_01281 2.31e-141 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NNGKMAKP_01282 3.12e-97 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
NNGKMAKP_01283 1.16e-237 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NNGKMAKP_01284 1.89e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NNGKMAKP_01285 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NNGKMAKP_01286 2.29e-278 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNGKMAKP_01287 7.5e-279 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKMAKP_01288 7.76e-115 licT - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NNGKMAKP_01289 7.04e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
NNGKMAKP_01290 3.25e-75 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NNGKMAKP_01291 1.71e-97 azlC - - E - - - branched-chain amino acid
NNGKMAKP_01292 1.46e-42 - - - S - - - Branched-chain amino acid transport protein (AzlD)
NNGKMAKP_01293 2.21e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNGKMAKP_01294 3.61e-69 jag - - S ko:K06346 - ko00000 R3H domain protein
NNGKMAKP_01295 6.79e-153 - - - L - - - Belongs to the 'phage' integrase family
NNGKMAKP_01296 1.52e-13 - - - S - - - sequence-specific DNA binding
NNGKMAKP_01305 1.92e-22 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
NNGKMAKP_01306 2.08e-92 - - - S ko:K06919 - ko00000 DNA primase
NNGKMAKP_01309 2.51e-09 - - - - - - - -
NNGKMAKP_01310 2.61e-67 - - - K - - - Transcriptional regulator C-terminal region
NNGKMAKP_01311 2.5e-59 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NNGKMAKP_01312 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NNGKMAKP_01313 5.53e-140 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
NNGKMAKP_01315 8.26e-86 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NNGKMAKP_01316 7.89e-61 hmpT - - S - - - ECF-type riboflavin transporter, S component
NNGKMAKP_01317 1.96e-54 - - - K - - - Acetyltransferase GNAT Family
NNGKMAKP_01319 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NNGKMAKP_01320 8.17e-123 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_01322 3.49e-28 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNGKMAKP_01323 1.78e-130 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NNGKMAKP_01324 4.78e-86 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
NNGKMAKP_01325 1.49e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
NNGKMAKP_01326 5.58e-69 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NNGKMAKP_01327 5.09e-60 - - - S - - - Short repeat of unknown function (DUF308)
NNGKMAKP_01328 2.58e-29 - - - K - - - Transcriptional regulator C-terminal region
NNGKMAKP_01329 1.8e-58 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NNGKMAKP_01330 2.6e-191 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NNGKMAKP_01332 4.98e-53 - - - K - - - LytTr DNA-binding domain
NNGKMAKP_01333 1.53e-143 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
NNGKMAKP_01334 6.75e-265 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNGKMAKP_01335 2.61e-21 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
NNGKMAKP_01336 6.96e-197 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKMAKP_01337 6.06e-230 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKMAKP_01338 7.43e-217 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNGKMAKP_01339 1.97e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNGKMAKP_01340 6.19e-254 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NNGKMAKP_01341 5.31e-278 yifK - - E ko:K03293 - ko00000 Amino acid permease
NNGKMAKP_01342 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNGKMAKP_01343 4.03e-70 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNGKMAKP_01344 1.97e-74 gpm2 - - G - - - Phosphoglycerate mutase family
NNGKMAKP_01345 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NNGKMAKP_01346 4.15e-26 - - - S - - - Cupredoxin-like domain
NNGKMAKP_01347 5.2e-57 - - - S - - - Cupredoxin-like domain
NNGKMAKP_01348 3.05e-191 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NNGKMAKP_01349 4.85e-30 - - - K - - - transcriptional regulator
NNGKMAKP_01350 2.16e-97 - - - S - - - intracellular protease amidase
NNGKMAKP_01351 2.12e-169 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NNGKMAKP_01352 4.94e-143 - - - K - - - helix_turn _helix lactose operon repressor
NNGKMAKP_01353 1.95e-289 treC - - G - - - Psort location Cytoplasmic, score
NNGKMAKP_01354 7.08e-52 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NNGKMAKP_01355 1.68e-157 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NNGKMAKP_01356 1.33e-139 - - - G - - - PTS system sorbose-specific iic component
NNGKMAKP_01357 1.32e-84 - - - G - - - PTS system sorbose subfamily IIB component
NNGKMAKP_01358 1.57e-100 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NNGKMAKP_01359 8.38e-178 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NNGKMAKP_01360 5.52e-219 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NNGKMAKP_01361 3.64e-203 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NNGKMAKP_01362 1.46e-249 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NNGKMAKP_01363 2.83e-93 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NNGKMAKP_01364 6.15e-168 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
NNGKMAKP_01365 5.93e-128 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NNGKMAKP_01366 6.31e-104 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NNGKMAKP_01367 5.3e-12 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NNGKMAKP_01368 2e-77 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
NNGKMAKP_01369 1.22e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NNGKMAKP_01371 2.03e-291 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NNGKMAKP_01372 3.42e-82 - - - C - - - FMN binding
NNGKMAKP_01373 5.05e-260 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NNGKMAKP_01374 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NNGKMAKP_01375 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NNGKMAKP_01377 2.55e-65 yugI - - J ko:K07570 - ko00000 general stress protein
NNGKMAKP_01378 1.15e-118 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NNGKMAKP_01379 1.08e-117 dedA - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NNGKMAKP_01380 1.48e-39 - - - S - - - Protein of unknown function (DUF1461)
NNGKMAKP_01381 6.85e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NNGKMAKP_01382 4.29e-77 yutD - - S - - - Protein of unknown function (DUF1027)
NNGKMAKP_01383 9.2e-73 - - - S - - - Calcineurin-like phosphoesterase
NNGKMAKP_01384 7.42e-240 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NNGKMAKP_01385 7e-124 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NNGKMAKP_01389 8.77e-16 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
NNGKMAKP_01390 2.51e-35 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
NNGKMAKP_01391 9.7e-123 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NNGKMAKP_01392 5.53e-153 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NNGKMAKP_01393 1.16e-129 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NNGKMAKP_01394 4e-153 yebC - - K - - - Transcriptional regulatory protein
NNGKMAKP_01395 4.81e-54 - - - S - - - VanZ like family
NNGKMAKP_01396 1.26e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NNGKMAKP_01397 9.17e-219 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NNGKMAKP_01399 2.23e-10 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NNGKMAKP_01401 3.43e-96 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNGKMAKP_01402 3.39e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NNGKMAKP_01403 6.12e-83 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NNGKMAKP_01404 1.97e-53 - - - K - - - Domain of unknown function (DUF1836)
NNGKMAKP_01405 2.71e-107 - - - S - - - membrane
NNGKMAKP_01406 1.39e-100 - - - S - - - VIT family
NNGKMAKP_01407 1.21e-188 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NNGKMAKP_01408 6.44e-73 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NNGKMAKP_01409 5.27e-148 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNGKMAKP_01410 2.14e-146 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNGKMAKP_01411 1.35e-154 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NNGKMAKP_01412 3.66e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NNGKMAKP_01413 2.16e-125 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NNGKMAKP_01414 1.01e-53 yjbH - - Q - - - Thioredoxin
NNGKMAKP_01415 2.49e-288 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NNGKMAKP_01416 1.87e-85 coiA - - S ko:K06198 - ko00000 Competence protein
NNGKMAKP_01417 1.53e-61 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NNGKMAKP_01418 1.45e-272 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NNGKMAKP_01431 1.16e-75 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNGKMAKP_01432 1.41e-237 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNGKMAKP_01433 3.77e-102 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
NNGKMAKP_01434 3.93e-87 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NNGKMAKP_01435 5.79e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
NNGKMAKP_01436 1.05e-143 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NNGKMAKP_01437 6.36e-95 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NNGKMAKP_01438 1.64e-267 nanB 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
NNGKMAKP_01439 1.24e-252 gph - - G ko:K03292 - ko00000 MFS/sugar transport protein
NNGKMAKP_01440 4e-229 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
NNGKMAKP_01441 7.33e-48 - - - G - - - single-species biofilm formation
NNGKMAKP_01442 1.53e-70 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NNGKMAKP_01443 2.9e-114 nanK - - GK - - - ROK family
NNGKMAKP_01444 4.39e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NNGKMAKP_01445 5.09e-118 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NNGKMAKP_01446 8.17e-96 - - - K - - - Helix-turn-helix domain, rpiR family
NNGKMAKP_01447 3.01e-79 yphA - - GM - - - NAD dependent epimerase/dehydratase family
NNGKMAKP_01448 1.35e-270 potE - - E - - - Amino Acid
NNGKMAKP_01449 5.75e-09 - - - - - - - -
NNGKMAKP_01450 3.83e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNGKMAKP_01451 1.19e-288 fusA1 - - J - - - elongation factor G
NNGKMAKP_01453 0.000485 yhaH - - S - - - Protein of unknown function (DUF805)
NNGKMAKP_01454 9.35e-09 - - - L - - - PLD-like domain
NNGKMAKP_01455 6.74e-197 - - - L - - - PLD-like domain
NNGKMAKP_01458 4.6e-142 - - - L - - - Initiator Replication protein
NNGKMAKP_01459 3.46e-46 - - - S - - - Replication initiator protein A (RepA) N-terminus
NNGKMAKP_01460 8.52e-198 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNGKMAKP_01461 2.36e-102 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NNGKMAKP_01462 3.92e-20 bglG - - K ko:K03488 - ko00000,ko03000 antiterminator
NNGKMAKP_01463 3.22e-161 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
NNGKMAKP_01465 3.14e-47 - - - - - - - -
NNGKMAKP_01466 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NNGKMAKP_01467 1.1e-47 - - - - - - - -
NNGKMAKP_01468 1.35e-93 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NNGKMAKP_01469 1.24e-237 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
NNGKMAKP_01470 5.12e-71 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NNGKMAKP_01471 5.82e-128 - - - P - - - cadmium resistance
NNGKMAKP_01472 4.67e-48 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NNGKMAKP_01473 1.02e-23 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NNGKMAKP_01478 1.28e-20 - - - - - - - -
NNGKMAKP_01482 1.78e-158 yvgN - - C - - - Aldo keto reductase
NNGKMAKP_01483 3.62e-75 yvbG - - U ko:K05595 - ko00000,ko02000 MarC family integral membrane protein
NNGKMAKP_01484 5.48e-230 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
NNGKMAKP_01485 3.18e-64 - - - S - - - Membrane
NNGKMAKP_01486 2.56e-94 - - - K - - - helix_turn_helix, arabinose operon control protein
NNGKMAKP_01487 6.67e-239 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NNGKMAKP_01488 1.54e-273 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NNGKMAKP_01489 8.21e-53 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NNGKMAKP_01490 1.42e-276 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
NNGKMAKP_01491 9.17e-141 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NNGKMAKP_01492 7.13e-241 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
NNGKMAKP_01494 1.63e-135 - - - L - - - Belongs to the 'phage' integrase family
NNGKMAKP_01496 6.25e-62 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NNGKMAKP_01498 1.91e-36 - - - K - - - Cro/C1-type HTH DNA-binding domain
NNGKMAKP_01499 5.51e-102 - - - S - - - Putative inner membrane protein (DUF1819)
NNGKMAKP_01500 2.04e-87 - - - S - - - Domain of unknown function (DUF1788)
NNGKMAKP_01501 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NNGKMAKP_01502 0.0 - - - L - - - restriction
NNGKMAKP_01503 3.5e-294 - - - S - - - TIGR02687 family
NNGKMAKP_01504 0.0 - 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Putative ATP-dependent Lon protease
NNGKMAKP_01506 8.75e-15 - - - - - - - -
NNGKMAKP_01509 2.11e-159 - - - - - - - -
NNGKMAKP_01511 4.12e-35 - - - - - - - -
NNGKMAKP_01512 5.87e-273 - - - O - - - ATPase family associated with various cellular activities (AAA)
NNGKMAKP_01513 2.36e-28 - - - - - - - -
NNGKMAKP_01514 1.93e-215 potE2 - - E ko:K03294 - ko00000 amino acid
NNGKMAKP_01515 1.17e-185 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NNGKMAKP_01516 2.6e-146 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NNGKMAKP_01517 1.32e-74 - - - K - - - Domain of unknown function (DUF1836)
NNGKMAKP_01518 3.01e-105 yitS - - S - - - EDD domain protein, DegV family
NNGKMAKP_01519 2.4e-60 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NNGKMAKP_01521 1.73e-49 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNGKMAKP_01522 1.6e-243 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NNGKMAKP_01523 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNGKMAKP_01524 1.51e-67 - - - C - - - Oxidoreductase NAD-binding domain
NNGKMAKP_01525 2.08e-120 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
NNGKMAKP_01526 1.75e-161 - - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
NNGKMAKP_01527 8.94e-55 - - - L ko:K07497 - ko00000 hmm pf00665
NNGKMAKP_01528 5.6e-35 - - - L ko:K07498 - ko00000 Transposase
NNGKMAKP_01529 3.43e-45 - - - P - - - Heavy-metal-associated domain
NNGKMAKP_01530 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
NNGKMAKP_01531 9.61e-07 - - - L ko:K07483 - ko00000 transposase activity
NNGKMAKP_01532 1.43e-101 - - - L ko:K07497 - ko00000 Integrase core domain
NNGKMAKP_01533 7.6e-168 - - - EGP - - - Major Facilitator Superfamily
NNGKMAKP_01534 8.54e-122 - - - EGP - - - Major Facilitator Superfamily
NNGKMAKP_01535 6.52e-90 - - - K - - - Transcriptional regulator, LysR family
NNGKMAKP_01536 7.4e-177 - - - G - - - Xylose isomerase-like TIM barrel
NNGKMAKP_01537 1.73e-148 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NNGKMAKP_01538 2.08e-271 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NNGKMAKP_01539 8.49e-175 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NNGKMAKP_01540 1.13e-89 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NNGKMAKP_01541 1.27e-180 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
NNGKMAKP_01545 2.1e-130 bsh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NNGKMAKP_01546 4.58e-90 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NNGKMAKP_01547 2.13e-100 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NNGKMAKP_01548 4.33e-73 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKMAKP_01549 1.23e-67 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NNGKMAKP_01550 1.2e-100 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NNGKMAKP_01551 6.66e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NNGKMAKP_01552 3.52e-100 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NNGKMAKP_01553 7.1e-34 - - - - - - - -
NNGKMAKP_01554 5.32e-18 - - - - - - - -
NNGKMAKP_01555 1.3e-142 rssA - - S - - - Phospholipase, patatin family
NNGKMAKP_01556 1.57e-174 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NNGKMAKP_01557 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NNGKMAKP_01558 1.34e-63 - - - S - - - VIT family
NNGKMAKP_01559 9.19e-304 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NNGKMAKP_01560 1.15e-53 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NNGKMAKP_01561 4.87e-183 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NNGKMAKP_01562 9.15e-181 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NNGKMAKP_01563 1.5e-147 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NNGKMAKP_01564 2.58e-280 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NNGKMAKP_01565 1.34e-51 - - - P - - - Voltage gated chloride channel
NNGKMAKP_01566 3.57e-267 tnpA1 - - L - - - Transposase
NNGKMAKP_01567 0.0 merA 1.16.1.1 - C ko:K00520 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NNGKMAKP_01568 1.14e-88 - - - K - - - MerR, DNA binding
NNGKMAKP_01569 8.97e-42 - - - P - - - Voltage gated chloride channel
NNGKMAKP_01570 2.01e-49 - - - P - - - Voltage gated chloride channel
NNGKMAKP_01571 1.9e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
NNGKMAKP_01572 3.59e-59 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NNGKMAKP_01573 1.85e-26 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NNGKMAKP_01574 2.98e-62 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NNGKMAKP_01581 9.16e-23 ps105 - - - - - - -
NNGKMAKP_01582 6.19e-50 blpT - - - - - - -
NNGKMAKP_01583 6.82e-19 - - - - - - - -
NNGKMAKP_01586 3.84e-191 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NNGKMAKP_01587 1.23e-46 - - - S - - - Glycosyltransferase like family 2
NNGKMAKP_01588 3.13e-47 - - - S - - - Glycosyltransferase like family 2
NNGKMAKP_01589 1.99e-46 - - - S - - - glycosyl transferase family 2
NNGKMAKP_01590 3.32e-38 - - - M - - - Glycosyltransferase like family 2
NNGKMAKP_01591 3.09e-137 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NNGKMAKP_01592 1.53e-65 - - - M - - - transferase activity, transferring glycosyl groups
NNGKMAKP_01593 2.68e-83 - - - M - - - transferase activity, transferring glycosyl groups
NNGKMAKP_01594 8.37e-44 arbY - - M - - - family 8
NNGKMAKP_01597 1.5e-42 - - - M - - - family 8
NNGKMAKP_01599 1.83e-41 - - - S - - - glycosyl transferase family 2
NNGKMAKP_01600 2.15e-36 cpsJ - - M - - - Glycosyltransferase group 2 family protein
NNGKMAKP_01601 1.29e-52 arbY - - M - - - family 8
NNGKMAKP_01602 8.32e-188 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NNGKMAKP_01603 2.57e-184 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NNGKMAKP_01604 1.63e-73 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NNGKMAKP_01605 1.02e-66 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NNGKMAKP_01606 2.07e-106 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NNGKMAKP_01607 1.5e-141 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NNGKMAKP_01608 2.17e-251 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NNGKMAKP_01609 3.77e-35 - - - - - - - -
NNGKMAKP_01610 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
NNGKMAKP_01611 7.37e-78 - - - T - - - Universal stress protein family
NNGKMAKP_01613 4.44e-271 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNGKMAKP_01614 3.5e-214 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NNGKMAKP_01615 4.27e-39 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NNGKMAKP_01616 1.5e-190 - - - V - - - RRXRR protein
NNGKMAKP_01617 6.57e-186 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NNGKMAKP_01618 2.72e-271 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NNGKMAKP_01619 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKMAKP_01620 2.76e-229 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NNGKMAKP_01621 8.44e-145 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
NNGKMAKP_01622 1.53e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
NNGKMAKP_01623 7.12e-68 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
NNGKMAKP_01624 4.49e-57 - - - K - - - helix_turn_helix isocitrate lyase regulation
NNGKMAKP_01625 3.37e-151 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNGKMAKP_01626 5.45e-130 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NNGKMAKP_01627 5.71e-28 - - - - - - - -
NNGKMAKP_01628 1.92e-73 - - - K - - - helix_turn_helix, arabinose operon control protein
NNGKMAKP_01629 8.79e-179 - - - G - - - PFAM major facilitator superfamily MFS_1
NNGKMAKP_01630 1.48e-129 gbpD - - S - - - Phospholipase/Carboxylesterase
NNGKMAKP_01631 2.01e-96 - - - GK - - - ROK family
NNGKMAKP_01632 3.47e-307 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNGKMAKP_01633 2.94e-82 - - - L ko:K07491 - ko00000 Transposase-like protein
NNGKMAKP_01634 4.53e-112 - - - S - - - Predicted membrane protein (DUF2207)
NNGKMAKP_01635 4.43e-70 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NNGKMAKP_01636 1.05e-229 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
NNGKMAKP_01637 7.61e-116 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNGKMAKP_01638 1.13e-91 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NNGKMAKP_01639 3.33e-76 yceE - - S - - - haloacid dehalogenase-like hydrolase
NNGKMAKP_01640 3.08e-50 - - - S - - - Domain of unknown function (DUF4811)
NNGKMAKP_01641 1.41e-246 ycnB - - U - - - Belongs to the major facilitator superfamily
NNGKMAKP_01642 9.36e-43 - - - K - - - MerR HTH family regulatory protein
NNGKMAKP_01643 7.43e-51 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNGKMAKP_01644 6.04e-90 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NNGKMAKP_01645 2.39e-147 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NNGKMAKP_01646 1.51e-101 yfiK - - K ko:K02479 - ko00000,ko02022 Bacterial regulatory proteins, luxR family
NNGKMAKP_01647 1.52e-120 baeS - - T - - - Histidine kinase
NNGKMAKP_01648 7.63e-102 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
NNGKMAKP_01649 3.19e-192 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NNGKMAKP_01650 1.69e-153 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NNGKMAKP_01651 1.4e-188 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NNGKMAKP_01652 1.61e-67 - - - S - - - Domain of unknown function (DUF956)
NNGKMAKP_01653 2.54e-89 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NNGKMAKP_01654 1.43e-164 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NNGKMAKP_01655 4.27e-207 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNGKMAKP_01656 4.73e-97 ung2 - - L - - - Uracil-DNA glycosylase
NNGKMAKP_01657 3.61e-43 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NNGKMAKP_01658 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NNGKMAKP_01659 1.56e-136 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NNGKMAKP_01660 7.44e-51 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NNGKMAKP_01661 3.37e-40 - - - S - - - CRISPR-associated protein (Cas_Csn2)
NNGKMAKP_01662 1.77e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
NNGKMAKP_01663 1.43e-27 - - - S - - - Protein of unknown function (DUF1700)
NNGKMAKP_01665 8.46e-23 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NNGKMAKP_01668 4.13e-296 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NNGKMAKP_01669 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
NNGKMAKP_01670 3.27e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NNGKMAKP_01671 8.99e-212 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NNGKMAKP_01672 3.85e-153 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNGKMAKP_01673 3.11e-133 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNGKMAKP_01674 1.19e-201 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNGKMAKP_01675 6.47e-168 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NNGKMAKP_01676 9.74e-147 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NNGKMAKP_01677 1.93e-138 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_01678 2.89e-86 yciB - - M - - - ErfK YbiS YcfS YnhG
NNGKMAKP_01679 6.58e-70 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNGKMAKP_01680 2.49e-285 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NNGKMAKP_01681 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NNGKMAKP_01682 2.22e-131 pgm3 - - G - - - phosphoglycerate mutase
NNGKMAKP_01683 2.05e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNGKMAKP_01684 6.33e-62 - - - C - - - Flavodoxin
NNGKMAKP_01685 5.24e-79 yphH - - S - - - Cupin domain
NNGKMAKP_01686 1.78e-60 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
NNGKMAKP_01687 3.58e-178 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NNGKMAKP_01688 4.23e-135 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NNGKMAKP_01689 2.65e-188 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNGKMAKP_01690 6.39e-120 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNGKMAKP_01691 7.51e-167 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NNGKMAKP_01692 9.46e-106 - - - C - - - nitroreductase
NNGKMAKP_01693 6.58e-108 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
NNGKMAKP_01694 1.16e-136 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
NNGKMAKP_01695 3.01e-214 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NNGKMAKP_01696 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
NNGKMAKP_01698 8.85e-192 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNGKMAKP_01699 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNGKMAKP_01700 3.63e-163 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NNGKMAKP_01701 3.29e-74 - - - S - - - Protein of unknown function (DUF4256)
NNGKMAKP_01704 1.49e-223 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NNGKMAKP_01705 7.47e-213 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NNGKMAKP_01706 3.86e-230 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNGKMAKP_01707 3.07e-291 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NNGKMAKP_01708 2.72e-186 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NNGKMAKP_01709 2.44e-70 - - - S - - - Protein of unknown function (DUF975)
NNGKMAKP_01710 3.93e-78 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NNGKMAKP_01711 1.78e-17 - - - - - - - -
NNGKMAKP_01712 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NNGKMAKP_01713 5.37e-279 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NNGKMAKP_01714 3.42e-112 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NNGKMAKP_01715 2.72e-191 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NNGKMAKP_01716 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NNGKMAKP_01717 8.41e-58 cps3F - - - - - - -
NNGKMAKP_01718 3.15e-108 - - - S - - - Membrane
NNGKMAKP_01719 0.0 - - - E - - - Amino acid permease
NNGKMAKP_01720 1.46e-292 cadA - - P - - - P-type ATPase
NNGKMAKP_01721 2.47e-146 degV - - S - - - EDD domain protein, DegV family
NNGKMAKP_01722 2.05e-189 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NNGKMAKP_01723 1.18e-69 - - - F - - - glutamine amidotransferase
NNGKMAKP_01724 1.07e-34 yuxO - - Q - - - Thioesterase superfamily
NNGKMAKP_01725 6.07e-186 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NNGKMAKP_01726 1.2e-175 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NNGKMAKP_01727 1.18e-103 - - - S - - - L,D-transpeptidase catalytic domain
NNGKMAKP_01728 1.18e-207 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
NNGKMAKP_01729 6.29e-21 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNGKMAKP_01730 6.3e-286 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NNGKMAKP_01731 6.86e-159 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NNGKMAKP_01732 1.39e-42 - - - S - - - Protein of unknown function (DUF1634)
NNGKMAKP_01733 3.86e-154 - - - S ko:K07090 - ko00000 membrane transporter protein
NNGKMAKP_01734 2.71e-106 lysR5 - - K - - - LysR substrate binding domain
NNGKMAKP_01735 5.31e-72 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
NNGKMAKP_01736 2.9e-14 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NNGKMAKP_01737 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NNGKMAKP_01738 5.56e-87 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NNGKMAKP_01739 2.64e-308 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NNGKMAKP_01740 1.6e-262 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NNGKMAKP_01745 2.78e-292 - - - L - - - Transposase
NNGKMAKP_01751 1.38e-165 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NNGKMAKP_01752 5.35e-235 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NNGKMAKP_01753 2.75e-199 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NNGKMAKP_01754 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NNGKMAKP_01755 6.07e-152 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NNGKMAKP_01757 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NNGKMAKP_01758 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NNGKMAKP_01759 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNGKMAKP_01760 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNGKMAKP_01761 1.33e-31 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
NNGKMAKP_01762 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NNGKMAKP_01763 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NNGKMAKP_01764 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NNGKMAKP_01765 4.67e-117 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NNGKMAKP_01766 1.73e-105 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NNGKMAKP_01767 1.21e-145 vanR - - K - - - response regulator
NNGKMAKP_01768 1.07e-190 hpk31 - - T - - - Histidine kinase
NNGKMAKP_01769 3.9e-111 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NNGKMAKP_01770 2.38e-189 - - - G - - - Transporter, major facilitator family protein
NNGKMAKP_01771 1.35e-278 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NNGKMAKP_01772 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_01773 4.44e-44 - - - K - - - Bacterial regulatory proteins, tetR family
NNGKMAKP_01774 6.2e-278 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NNGKMAKP_01775 4.75e-316 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NNGKMAKP_01776 1.29e-11 - - - - - - - -
NNGKMAKP_01777 5.29e-59 yyaT - - K ko:K02348 - ko00000 protein acetylation
NNGKMAKP_01778 1.2e-67 ymdB - - L - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
NNGKMAKP_01779 2.23e-94 lemA - - S ko:K03744 - ko00000 LemA family
NNGKMAKP_01780 1.77e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NNGKMAKP_01782 0.0 - - - L - - - DNA helicase
NNGKMAKP_01783 2.75e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNGKMAKP_01784 2.82e-217 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NNGKMAKP_01785 1.96e-129 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NNGKMAKP_01786 8.84e-24 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NNGKMAKP_01787 1.18e-78 - - - L - - - Resolvase, N-terminal domain
NNGKMAKP_01788 3.22e-120 - - - L - - - Probable transposase
NNGKMAKP_01789 8.52e-96 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NNGKMAKP_01790 6.79e-51 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NNGKMAKP_01791 5.39e-40 - - - K - - - Bacterial regulatory proteins, tetR family
NNGKMAKP_01792 2.97e-54 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
NNGKMAKP_01793 3.78e-191 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NNGKMAKP_01794 1.95e-163 - - - - - - - -
NNGKMAKP_01795 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NNGKMAKP_01796 6.96e-131 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NNGKMAKP_01797 4.87e-112 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NNGKMAKP_01798 5.37e-169 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NNGKMAKP_01799 2.78e-31 veg - - S - - - Biofilm formation stimulator VEG
NNGKMAKP_01800 6.28e-114 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NNGKMAKP_01801 2.23e-170 arcT - - E - - - Cys/Met metabolism PLP-dependent enzyme
NNGKMAKP_01802 5.91e-61 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NNGKMAKP_01803 1.46e-147 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NNGKMAKP_01804 5.22e-194 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NNGKMAKP_01805 2.45e-254 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NNGKMAKP_01806 1.13e-248 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NNGKMAKP_01807 7.05e-190 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNGKMAKP_01808 1.1e-158 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNGKMAKP_01809 7.49e-139 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NNGKMAKP_01810 6.82e-235 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NNGKMAKP_01811 1.79e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NNGKMAKP_01812 7.37e-175 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NNGKMAKP_01813 2.43e-72 - - - EGP - - - Transmembrane secretion effector
NNGKMAKP_01814 1.95e-257 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NNGKMAKP_01815 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNGKMAKP_01816 3.2e-27 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NNGKMAKP_01818 3.36e-140 dkgB - - S - - - reductase
NNGKMAKP_01819 1.82e-33 - - - - - - - -
NNGKMAKP_01820 5.99e-05 - - - F - - - Phosphorylase family
NNGKMAKP_01821 9.8e-81 - - - F - - - Phosphorylase superfamily
NNGKMAKP_01822 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NNGKMAKP_01823 2.45e-79 ytkL - - S - - - Beta-lactamase superfamily domain
NNGKMAKP_01824 3.31e-122 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NNGKMAKP_01825 1.94e-157 yibE - - S - - - overlaps another CDS with the same product name
NNGKMAKP_01826 9.53e-110 - - - S - - - overlaps another CDS with the same product name
NNGKMAKP_01828 4.91e-63 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
NNGKMAKP_01830 6.15e-26 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 PIF1-like helicase
NNGKMAKP_01832 3.3e-91 - - - - - - - -
NNGKMAKP_01833 2.74e-16 - - - - - - - -
NNGKMAKP_01834 6.77e-219 - - - L - - - Probable transposase
NNGKMAKP_01835 2.15e-96 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
NNGKMAKP_01836 2.03e-110 - - - S - - - hydrolase
NNGKMAKP_01837 1.99e-260 ywfO - - S ko:K06885 - ko00000 HD domain protein
NNGKMAKP_01838 7.48e-77 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNGKMAKP_01839 1.65e-108 - - - F - - - glutamine amidotransferase
NNGKMAKP_01840 3.61e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
NNGKMAKP_01841 1.75e-57 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NNGKMAKP_01842 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NNGKMAKP_01844 4.42e-253 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNGKMAKP_01845 1.93e-240 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NNGKMAKP_01846 2.05e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NNGKMAKP_01847 6.42e-79 - - - - - - - -
NNGKMAKP_01848 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
NNGKMAKP_01850 2.06e-98 - - - S - - - Cell surface protein
NNGKMAKP_01852 3.53e-230 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NNGKMAKP_01853 1.54e-81 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
NNGKMAKP_01854 1.63e-224 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NNGKMAKP_01855 1.32e-282 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NNGKMAKP_01856 3.01e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NNGKMAKP_01857 7.6e-182 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNGKMAKP_01859 5e-64 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NNGKMAKP_01860 9.14e-117 yunF - - F - - - Protein of unknown function DUF72
NNGKMAKP_01861 6.62e-196 yngD - - S ko:K07097 - ko00000 DHHA1 domain
NNGKMAKP_01862 1.8e-56 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NNGKMAKP_01863 4.12e-79 - - - L - - - Resolvase, N-terminal domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)