ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LKPMBICO_00001 3.46e-39 - - - S - - - Belongs to the HesB IscA family
LKPMBICO_00002 1.7e-84 icaB - - G - - - Polysaccharide deacetylase
LKPMBICO_00004 3.12e-68 - - - K - - - LysR substrate binding domain
LKPMBICO_00005 3.35e-152 - - - S - - - Conserved hypothetical protein 698
LKPMBICO_00006 2.06e-253 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
LKPMBICO_00007 3.1e-137 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKPMBICO_00008 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LKPMBICO_00009 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
LKPMBICO_00010 1.1e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LKPMBICO_00011 1.81e-201 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LKPMBICO_00012 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
LKPMBICO_00013 1.45e-194 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LKPMBICO_00014 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKPMBICO_00015 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKPMBICO_00016 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LKPMBICO_00017 6.48e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LKPMBICO_00018 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LKPMBICO_00019 4.29e-140 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
LKPMBICO_00020 7.68e-147 - - - S - - - Glycosyl transferase family 2
LKPMBICO_00021 2.26e-81 - - - D - - - peptidase
LKPMBICO_00022 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LKPMBICO_00023 5.27e-80 - - - S - - - Protein of unknown function (DUF1211)
LKPMBICO_00024 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LKPMBICO_00025 3.25e-307 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LKPMBICO_00026 5.01e-22 yneR - - - - - - -
LKPMBICO_00027 7.19e-290 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LKPMBICO_00028 7.54e-284 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
LKPMBICO_00029 3.32e-136 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LKPMBICO_00030 6.05e-191 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LKPMBICO_00031 4.15e-12 yobS - - K - - - Bacterial regulatory proteins, tetR family
LKPMBICO_00032 4.44e-141 - - - U ko:K05340 - ko00000,ko02000 sugar transport
LKPMBICO_00033 1.31e-212 - - - S - - - Putative threonine/serine exporter
LKPMBICO_00034 5.14e-89 - - - J - - - Acetyltransferase (GNAT) domain
LKPMBICO_00035 9.44e-121 yicL - - EG - - - EamA-like transporter family
LKPMBICO_00036 2.76e-279 pepF - - E - - - Oligopeptidase F
LKPMBICO_00037 3.35e-136 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LKPMBICO_00038 1.21e-225 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LKPMBICO_00039 8.84e-173 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
LKPMBICO_00040 1.02e-80 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LKPMBICO_00041 9.15e-218 - - - S - - - Putative peptidoglycan binding domain
LKPMBICO_00042 2.33e-41 - - - K - - - Transcriptional regulator, MarR family
LKPMBICO_00043 7.58e-270 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_00044 1.58e-286 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
LKPMBICO_00045 5.78e-135 yxeH - - S - - - hydrolase
LKPMBICO_00046 2.43e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LKPMBICO_00047 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKPMBICO_00048 7.57e-126 yycH - - S - - - YycH protein
LKPMBICO_00049 1.66e-100 yycI - - S - - - YycH protein
LKPMBICO_00050 4.78e-41 - - - S - - - YjbR
LKPMBICO_00051 1.46e-147 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
LKPMBICO_00052 1.9e-186 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
LKPMBICO_00053 7.88e-94 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LKPMBICO_00054 7.57e-52 - - - GM - - - NAD(P)H-binding
LKPMBICO_00055 3.67e-34 - - - K - - - MarR family transcriptional regulator
LKPMBICO_00056 3.84e-112 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LKPMBICO_00057 2.87e-60 - - - S - - - PD-(D/E)XK nuclease family transposase
LKPMBICO_00058 1.6e-261 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter
LKPMBICO_00059 4.72e-172 - - - S - - - interspecies interaction between organisms
LKPMBICO_00062 4.21e-05 - - - D - - - GA module
LKPMBICO_00064 2.5e-07 - 2.7.8.12 - V ko:K09809 - ko00000,ko01000 Glycosyl transferase, family 2
LKPMBICO_00065 7e-35 arbx - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
LKPMBICO_00066 2.82e-187 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
LKPMBICO_00067 4.11e-185 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
LKPMBICO_00068 7.22e-107 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LKPMBICO_00069 7.13e-140 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
LKPMBICO_00070 3.08e-251 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
LKPMBICO_00071 2.65e-35 - - - - - - - -
LKPMBICO_00072 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
LKPMBICO_00073 4.09e-77 - - - T - - - Universal stress protein family
LKPMBICO_00075 3.13e-271 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKPMBICO_00076 3.5e-214 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LKPMBICO_00080 1.61e-90 - - - O - - - ADP-ribosylglycohydrolase
LKPMBICO_00081 2.6e-130 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKPMBICO_00082 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LKPMBICO_00083 2.28e-91 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
LKPMBICO_00084 9.9e-105 ylmH - - S - - - S4 domain protein
LKPMBICO_00085 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
LKPMBICO_00086 1.15e-42 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LKPMBICO_00087 4.52e-229 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LKPMBICO_00088 6.07e-240 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LKPMBICO_00089 6.44e-76 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LKPMBICO_00090 1.23e-194 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LKPMBICO_00091 1.27e-234 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LKPMBICO_00092 3.64e-172 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LKPMBICO_00093 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LKPMBICO_00094 1.05e-13 ftsL - - D - - - Essential cell division protein
LKPMBICO_00095 3.67e-180 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LKPMBICO_00096 5.35e-82 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LKPMBICO_00098 5.43e-196 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
LKPMBICO_00099 1.16e-05 - - - S - - - Protein of unknown function (DUF4044)
LKPMBICO_00100 4.54e-124 ybcH - - D ko:K06889 - ko00000 Alpha beta
LKPMBICO_00101 2.65e-137 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LKPMBICO_00102 2.01e-115 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_00103 3.02e-122 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LKPMBICO_00104 7.95e-163 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LKPMBICO_00105 3.56e-98 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LKPMBICO_00106 9.34e-71 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
LKPMBICO_00107 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LKPMBICO_00108 2.35e-207 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
LKPMBICO_00109 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
LKPMBICO_00110 2.27e-102 radC - - L ko:K03630 - ko00000 DNA repair protein
LKPMBICO_00111 8.51e-170 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LKPMBICO_00112 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LKPMBICO_00113 1.44e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LKPMBICO_00114 4.14e-204 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LKPMBICO_00115 2.82e-224 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LKPMBICO_00116 6.33e-73 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LKPMBICO_00117 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LKPMBICO_00118 6.66e-30 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
LKPMBICO_00119 6.66e-247 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LKPMBICO_00121 6.35e-97 uspA - - T - - - universal stress protein
LKPMBICO_00122 1.31e-70 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LKPMBICO_00123 2.99e-252 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LKPMBICO_00124 2.95e-158 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LKPMBICO_00126 1.03e-96 yviA - - S - - - Protein of unknown function (DUF421)
LKPMBICO_00127 3e-36 - - - S - - - Protein of unknown function (DUF3290)
LKPMBICO_00128 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LKPMBICO_00129 0.0 - - - S - - - membrane
LKPMBICO_00130 4.3e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LKPMBICO_00131 1.44e-267 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LKPMBICO_00132 1.68e-128 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
LKPMBICO_00133 3.54e-178 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LKPMBICO_00135 1.68e-22 - - - - - - - -
LKPMBICO_00136 7.72e-257 oatA - - I - - - Acyltransferase
LKPMBICO_00137 1.65e-272 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LKPMBICO_00138 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LKPMBICO_00139 2.44e-178 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKPMBICO_00142 2.85e-46 - - - S ko:K07095 - ko00000 Phosphoesterase
LKPMBICO_00143 8.89e-94 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LKPMBICO_00144 3.55e-79 yslB - - S - - - Protein of unknown function (DUF2507)
LKPMBICO_00145 2.13e-53 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LKPMBICO_00146 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LKPMBICO_00147 3.86e-20 cvpA - - S - - - Colicin V production protein
LKPMBICO_00148 3.67e-17 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LKPMBICO_00149 4.23e-44 yrzB - - S - - - Belongs to the UPF0473 family
LKPMBICO_00150 1.57e-78 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LKPMBICO_00151 2.44e-49 yrzL - - S - - - Belongs to the UPF0297 family
LKPMBICO_00152 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LKPMBICO_00153 4.29e-236 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LKPMBICO_00154 1.25e-153 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
LKPMBICO_00155 3.5e-18 - - - - - - - -
LKPMBICO_00156 2.76e-184 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LKPMBICO_00157 4.44e-85 lutC - - S ko:K00782 - ko00000 LUD domain
LKPMBICO_00158 4.95e-311 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
LKPMBICO_00159 3.54e-150 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
LKPMBICO_00160 2.92e-264 - - - E ko:K03294 - ko00000 Amino Acid
LKPMBICO_00162 3.61e-79 uspA3 - - T - - - universal stress protein
LKPMBICO_00164 2.13e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
LKPMBICO_00165 5.96e-263 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LKPMBICO_00166 6.77e-230 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LKPMBICO_00167 1.45e-193 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LKPMBICO_00168 2.19e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LKPMBICO_00169 1.15e-286 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LKPMBICO_00170 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LKPMBICO_00171 4.38e-256 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LKPMBICO_00172 1.84e-203 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LKPMBICO_00173 2.09e-111 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LKPMBICO_00174 1.06e-84 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
LKPMBICO_00175 5.2e-116 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LKPMBICO_00176 2.24e-187 ymfH - - S - - - Peptidase M16
LKPMBICO_00177 2.59e-137 ymfF - - S - - - Peptidase M16 inactive domain protein
LKPMBICO_00178 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LKPMBICO_00179 2.62e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LKPMBICO_00180 2.88e-124 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
LKPMBICO_00181 2.89e-83 - - - J ko:K03976 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
LKPMBICO_00182 1.61e-207 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LKPMBICO_00183 3.47e-250 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKPMBICO_00184 1.17e-23 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
LKPMBICO_00185 1.53e-163 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
LKPMBICO_00186 1.59e-38 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LKPMBICO_00187 1.1e-284 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LKPMBICO_00188 4.54e-87 ybbR - - S - - - YbbR-like protein
LKPMBICO_00189 1.95e-162 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LKPMBICO_00190 3.92e-92 - - - S - - - Protein of unknown function (DUF1361)
LKPMBICO_00191 4.26e-146 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
LKPMBICO_00192 3.34e-90 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LKPMBICO_00193 1e-72 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
LKPMBICO_00194 4.05e-180 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
LKPMBICO_00195 2.16e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LKPMBICO_00196 1.68e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
LKPMBICO_00197 1.37e-53 - - - - - - - -
LKPMBICO_00198 4.3e-91 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LKPMBICO_00199 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LKPMBICO_00200 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LKPMBICO_00201 4.45e-224 eriC - - P ko:K03281 - ko00000 chloride
LKPMBICO_00202 5.39e-189 - - - E - - - Major Facilitator Superfamily
LKPMBICO_00203 8.04e-212 yclK - - T - - - Histidine kinase
LKPMBICO_00204 1.95e-134 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
LKPMBICO_00205 3.5e-168 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKPMBICO_00206 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LKPMBICO_00207 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LKPMBICO_00208 1.99e-264 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LKPMBICO_00209 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKPMBICO_00210 2.76e-175 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
LKPMBICO_00212 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LKPMBICO_00213 2.05e-191 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LKPMBICO_00214 9.11e-195 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LKPMBICO_00215 5.03e-161 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LKPMBICO_00216 5.61e-102 - - - GM - - - NAD dependent epimerase dehydratase family protein
LKPMBICO_00217 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LKPMBICO_00218 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LKPMBICO_00219 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LKPMBICO_00220 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LKPMBICO_00221 4.11e-143 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LKPMBICO_00222 7.14e-169 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LKPMBICO_00223 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
LKPMBICO_00224 1.02e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LKPMBICO_00225 1.85e-104 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKPMBICO_00226 1.03e-110 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LKPMBICO_00227 4.95e-81 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
LKPMBICO_00228 1.85e-206 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LKPMBICO_00229 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LKPMBICO_00230 1.49e-121 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
LKPMBICO_00231 1.43e-104 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LKPMBICO_00232 1.13e-68 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
LKPMBICO_00233 2.47e-158 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
LKPMBICO_00234 4.93e-200 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
LKPMBICO_00235 0.0 ydaO - - E - - - amino acid
LKPMBICO_00236 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
LKPMBICO_00237 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LKPMBICO_00238 1.7e-46 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LKPMBICO_00239 1.43e-41 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LKPMBICO_00240 1.52e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LKPMBICO_00241 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
LKPMBICO_00242 2.51e-206 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LKPMBICO_00243 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LKPMBICO_00244 3.7e-88 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
LKPMBICO_00245 1.15e-177 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
LKPMBICO_00246 6.03e-105 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
LKPMBICO_00247 1.15e-119 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LKPMBICO_00248 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
LKPMBICO_00249 3.28e-105 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LKPMBICO_00250 2.18e-83 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LKPMBICO_00251 4.16e-39 yaaL - - S - - - Protein of unknown function (DUF2508)
LKPMBICO_00252 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LKPMBICO_00253 3.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LKPMBICO_00254 5.45e-268 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKPMBICO_00255 2.23e-80 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LKPMBICO_00256 1.11e-96 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LKPMBICO_00257 3.91e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
LKPMBICO_00258 1.81e-58 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
LKPMBICO_00259 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKPMBICO_00260 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKPMBICO_00261 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LKPMBICO_00262 7.33e-71 - - - - - - - -
LKPMBICO_00263 2.18e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LKPMBICO_00264 2.21e-97 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LKPMBICO_00265 9.98e-150 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LKPMBICO_00266 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LKPMBICO_00267 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LKPMBICO_00268 3.08e-16 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LKPMBICO_00269 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LKPMBICO_00270 1.93e-92 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
LKPMBICO_00271 1.88e-138 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKPMBICO_00272 3.45e-73 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LKPMBICO_00273 2.26e-263 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LKPMBICO_00274 1.05e-312 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LKPMBICO_00275 1.38e-195 yacL - - S - - - domain protein
LKPMBICO_00276 1.14e-283 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LKPMBICO_00277 2.38e-95 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
LKPMBICO_00278 1.17e-25 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
LKPMBICO_00279 5.18e-281 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
LKPMBICO_00280 5.58e-45 - - - S - - - Enterocin A Immunity
LKPMBICO_00281 4.1e-109 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LKPMBICO_00282 2.13e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
LKPMBICO_00283 7.6e-148 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKPMBICO_00285 7.99e-55 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LKPMBICO_00286 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
LKPMBICO_00287 7.58e-165 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LKPMBICO_00288 6.25e-307 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LKPMBICO_00289 3.32e-113 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LKPMBICO_00290 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
LKPMBICO_00291 1.5e-115 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKPMBICO_00294 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
LKPMBICO_00295 8.12e-121 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LKPMBICO_00296 2.49e-15 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
LKPMBICO_00297 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LKPMBICO_00298 3.03e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
LKPMBICO_00299 2.18e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
LKPMBICO_00300 5.64e-69 gtcA - - S - - - Teichoic acid glycosylation protein
LKPMBICO_00301 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LKPMBICO_00302 9.8e-152 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
LKPMBICO_00303 1.31e-154 - - - S - - - Sulfite exporter TauE/SafE
LKPMBICO_00304 2.43e-90 - - - K - - - Sugar-specific transcriptional regulator TrmB
LKPMBICO_00305 1.65e-214 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LKPMBICO_00306 8.6e-230 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
LKPMBICO_00307 0.0 - - - E - - - Amino acid permease
LKPMBICO_00308 9.38e-110 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LKPMBICO_00309 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LKPMBICO_00310 3.84e-95 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LKPMBICO_00311 2.47e-270 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
LKPMBICO_00312 1.15e-126 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
LKPMBICO_00313 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LKPMBICO_00316 1.39e-201 yfmL - - L - - - DEAD DEAH box helicase
LKPMBICO_00317 1.08e-160 mocA - - S - - - Oxidoreductase
LKPMBICO_00318 7.99e-33 - - - S - - - Domain of unknown function (DUF4828)
LKPMBICO_00319 1.99e-214 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LKPMBICO_00320 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LKPMBICO_00321 1.82e-243 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LKPMBICO_00322 9.63e-158 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
LKPMBICO_00323 8.3e-210 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LKPMBICO_00324 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LKPMBICO_00325 1.03e-272 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LKPMBICO_00326 2.08e-43 - - - O - - - ADP-ribosylglycohydrolase
LKPMBICO_00327 1.02e-277 gdhA 1.4.1.3, 1.4.1.4 - E ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
LKPMBICO_00328 2.78e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LKPMBICO_00329 1.87e-41 - - - K - - - GNAT family
LKPMBICO_00330 1.96e-54 - - - - - - - -
LKPMBICO_00332 1.27e-228 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
LKPMBICO_00333 1.3e-118 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LKPMBICO_00334 1.79e-148 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LKPMBICO_00335 5.56e-124 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LKPMBICO_00336 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
LKPMBICO_00337 6.02e-46 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LKPMBICO_00338 3.15e-254 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
LKPMBICO_00339 1.37e-96 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LKPMBICO_00340 2.58e-77 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
LKPMBICO_00341 5.7e-82 - - - S - - - ECF transporter, substrate-specific component
LKPMBICO_00342 2.15e-162 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
LKPMBICO_00343 3.4e-313 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
LKPMBICO_00344 7.97e-90 mleR - - K - - - LysR family
LKPMBICO_00345 3.65e-74 napB - - K - - - transcriptional
LKPMBICO_00346 1.17e-52 - - - K - - - Bacterial regulatory proteins, tetR family
LKPMBICO_00347 2.3e-78 usp2 - - T - - - Belongs to the universal stress protein A family
LKPMBICO_00348 2.15e-59 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
LKPMBICO_00349 1.98e-10 - - - M - - - Rib/alpha-like repeat
LKPMBICO_00352 2.41e-129 ypuA - - S - - - Protein of unknown function (DUF1002)
LKPMBICO_00353 1.28e-76 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
LKPMBICO_00354 1.32e-204 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LKPMBICO_00355 2.88e-53 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LKPMBICO_00356 3.63e-267 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LKPMBICO_00357 7.94e-249 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LKPMBICO_00358 3.06e-301 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LKPMBICO_00359 4.82e-20 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
LKPMBICO_00360 4.28e-223 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
LKPMBICO_00361 7.75e-51 - - - L - - - Transposase
LKPMBICO_00362 3.47e-75 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LKPMBICO_00363 5.77e-120 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LKPMBICO_00364 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
LKPMBICO_00365 5.1e-92 ywlG - - S - - - Belongs to the UPF0340 family
LKPMBICO_00366 1.2e-81 - - - S - - - Acetyltransferase (GNAT) domain
LKPMBICO_00369 1.44e-31 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LKPMBICO_00370 9.63e-18 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
LKPMBICO_00371 4.9e-67 - - - K - - - Cro/C1-type HTH DNA-binding domain
LKPMBICO_00372 3.93e-207 spoVK - - O ko:K06413 - ko00000 PFAM ATPase family associated with various cellular activities (AAA)
LKPMBICO_00373 8.5e-97 - - - - - - - -
LKPMBICO_00374 4.21e-39 - - - - - - - -
LKPMBICO_00375 1.89e-76 - - - - - - - -
LKPMBICO_00376 7.95e-128 - - - S - - - Domain of unknown function (DUF4343)
LKPMBICO_00377 0.0 - - - L - - - helicase activity
LKPMBICO_00378 2.98e-233 - - - K - - - DNA binding
LKPMBICO_00379 1.55e-144 res 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
LKPMBICO_00380 0.0 res 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
LKPMBICO_00381 6.91e-277 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
LKPMBICO_00383 8.95e-215 mcrC - - V ko:K19147 - ko00000,ko02048 Psort location Cytoplasmic, score
LKPMBICO_00384 0.0 mcrB - - V ko:K07452 - ko00000,ko01000,ko02048 ATPase family associated with various cellular activities (AAA)
LKPMBICO_00387 2.76e-271 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKPMBICO_00388 5.09e-183 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
LKPMBICO_00389 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKPMBICO_00390 4.18e-294 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LKPMBICO_00391 1.34e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKPMBICO_00392 1.39e-204 camS - - S - - - sex pheromone
LKPMBICO_00393 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LKPMBICO_00394 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LKPMBICO_00395 2.33e-182 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LKPMBICO_00398 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LKPMBICO_00399 2.4e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LKPMBICO_00400 1.32e-166 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LKPMBICO_00401 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LKPMBICO_00402 5.03e-100 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
LKPMBICO_00403 1.83e-118 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LKPMBICO_00404 1.23e-62 yabR - - J ko:K07571 - ko00000 RNA binding
LKPMBICO_00405 1.49e-28 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LKPMBICO_00406 1.1e-42 yabO - - J - - - S4 domain protein
LKPMBICO_00407 3.29e-173 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LKPMBICO_00408 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LKPMBICO_00409 1.45e-95 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LKPMBICO_00410 8.16e-202 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LKPMBICO_00411 2.2e-110 - - - S - - - (CBS) domain
LKPMBICO_00412 4.44e-180 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKPMBICO_00413 4.09e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKPMBICO_00414 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LKPMBICO_00415 8.18e-73 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LKPMBICO_00416 2.69e-127 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
LKPMBICO_00417 1.44e-142 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LKPMBICO_00419 2.6e-62 - - - M - - - LysM domain protein
LKPMBICO_00420 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LKPMBICO_00421 4.51e-111 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LKPMBICO_00422 2.1e-41 - - - K - - - transcriptional regulator (TetR family)
LKPMBICO_00423 1.76e-137 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LKPMBICO_00424 3.65e-110 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_00425 5.1e-86 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LKPMBICO_00426 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LKPMBICO_00427 4.89e-308 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
LKPMBICO_00429 2.29e-79 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LKPMBICO_00430 1.04e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LKPMBICO_00431 6.22e-160 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LKPMBICO_00432 8.86e-138 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKPMBICO_00433 8.76e-140 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKPMBICO_00434 3.22e-127 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKPMBICO_00435 4.47e-71 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LKPMBICO_00436 1.93e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKPMBICO_00437 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LKPMBICO_00438 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LKPMBICO_00439 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LKPMBICO_00440 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LKPMBICO_00441 7.34e-142 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LKPMBICO_00442 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LKPMBICO_00443 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LKPMBICO_00444 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LKPMBICO_00445 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LKPMBICO_00446 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LKPMBICO_00447 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LKPMBICO_00448 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LKPMBICO_00449 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKPMBICO_00450 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LKPMBICO_00451 3.84e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LKPMBICO_00452 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LKPMBICO_00453 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LKPMBICO_00454 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LKPMBICO_00455 8.95e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LKPMBICO_00456 1.62e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LKPMBICO_00457 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LKPMBICO_00458 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LKPMBICO_00459 4.58e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LKPMBICO_00460 1.34e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LKPMBICO_00461 6.55e-130 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LKPMBICO_00462 2.82e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LKPMBICO_00463 3.24e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LKPMBICO_00464 8.55e-218 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LKPMBICO_00465 3.04e-100 - - - K - - - rpiR family
LKPMBICO_00466 9.97e-67 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
LKPMBICO_00467 4.8e-187 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LKPMBICO_00468 2.79e-14 - - - K - - - Acetyltransferase (GNAT) domain
LKPMBICO_00469 5.79e-240 steT - - E ko:K03294 - ko00000 amino acid
LKPMBICO_00470 1.88e-104 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LKPMBICO_00471 1.4e-110 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LKPMBICO_00472 6.87e-126 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKPMBICO_00473 2.45e-132 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_00474 1.32e-17 - - - - - - - -
LKPMBICO_00475 4.49e-123 - - - - - - - -
LKPMBICO_00476 2.42e-14 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
LKPMBICO_00477 1e-68 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LKPMBICO_00478 1.76e-268 yhdG - - E ko:K03294 - ko00000 Amino Acid
LKPMBICO_00479 2.44e-315 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LKPMBICO_00480 0.0 - - - L - - - Helicase C-terminal domain protein
LKPMBICO_00481 1.77e-101 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LKPMBICO_00482 6.84e-232 yhdP - - S - - - Transporter associated domain
LKPMBICO_00483 1.95e-33 - - - - - - - -
LKPMBICO_00484 2.4e-94 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LKPMBICO_00485 1.13e-162 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
LKPMBICO_00486 2.78e-126 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LKPMBICO_00487 1.41e-92 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LKPMBICO_00488 6.6e-198 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
LKPMBICO_00489 1.97e-174 - - - V - - - MatE
LKPMBICO_00490 2.95e-58 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKPMBICO_00491 1.36e-111 - - - S - - - Alpha beta hydrolase
LKPMBICO_00492 2.14e-121 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LKPMBICO_00493 4.28e-218 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LKPMBICO_00494 4.34e-138 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
LKPMBICO_00495 4.48e-131 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LKPMBICO_00496 7.29e-46 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
LKPMBICO_00497 3.13e-68 ccl - - S - - - QueT transporter
LKPMBICO_00499 6.6e-84 - - - S - - - Uncharacterised protein, DegV family COG1307
LKPMBICO_00500 2.37e-28 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKPMBICO_00501 1.09e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKPMBICO_00502 7.86e-46 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LKPMBICO_00503 8.48e-110 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LKPMBICO_00504 1.52e-157 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LKPMBICO_00505 1.19e-65 - - - S - - - Threonine/Serine exporter, ThrE
LKPMBICO_00506 9.59e-104 - - - S - - - Putative threonine/serine exporter
LKPMBICO_00507 1.37e-37 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LKPMBICO_00508 3.57e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
LKPMBICO_00509 1.17e-116 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LKPMBICO_00510 2.39e-27 - - - - - - - -
LKPMBICO_00511 9.17e-75 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
LKPMBICO_00512 4.48e-24 - - - - - - - -
LKPMBICO_00513 3.45e-81 - - - I - - - alpha/beta hydrolase fold
LKPMBICO_00514 2.61e-52 - - - S - - - branched-chain amino acid
LKPMBICO_00515 1.78e-132 - - - E - - - AzlC protein
LKPMBICO_00516 1.81e-24 - - - - - - - -
LKPMBICO_00517 8.83e-164 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LKPMBICO_00518 1.48e-141 yhgE - - V ko:K01421 - ko00000 domain protein
LKPMBICO_00520 0.000331 - - - S - - - zinc-ribbon domain
LKPMBICO_00521 8.68e-159 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LKPMBICO_00522 5.45e-218 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LKPMBICO_00523 2.26e-148 ydbI - - K - - - AI-2E family transporter
LKPMBICO_00524 1.18e-75 - - - EG - - - EamA-like transporter family
LKPMBICO_00525 2.14e-96 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
LKPMBICO_00526 1.97e-147 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LKPMBICO_00527 2.21e-86 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LKPMBICO_00528 7.71e-209 - - - C - - - Luciferase-like monooxygenase
LKPMBICO_00529 1.7e-55 hxlR - - K - - - Transcriptional regulator, HxlR family
LKPMBICO_00530 4.71e-219 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LKPMBICO_00531 2.09e-132 gntR - - K - - - UbiC transcription regulator-associated domain protein
LKPMBICO_00532 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LKPMBICO_00533 5.94e-107 pncA - - Q - - - isochorismatase
LKPMBICO_00534 1.14e-81 pgm1 - - G - - - phosphoglycerate mutase
LKPMBICO_00535 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKPMBICO_00536 1.68e-108 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LKPMBICO_00537 6.78e-314 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LKPMBICO_00538 2.38e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LKPMBICO_00540 1.47e-67 - - - S - - - peptidoglycan catabolic process
LKPMBICO_00541 1.58e-198 - - - M - - - Belongs to the BCCT transporter (TC 2.A.15) family
LKPMBICO_00542 1.25e-108 - - - M - - - Nucleotidyl transferase
LKPMBICO_00543 3.02e-222 - - - M - - - Choline/ethanolamine kinase
LKPMBICO_00544 2.31e-113 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LKPMBICO_00545 8.87e-215 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LKPMBICO_00546 5.36e-161 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LKPMBICO_00547 2.28e-220 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
LKPMBICO_00548 1.54e-190 XK27_08315 - - M - - - Sulfatase
LKPMBICO_00549 4.55e-20 - - - - - - - -
LKPMBICO_00550 7.02e-59 cps3I - - G - - - Acyltransferase family
LKPMBICO_00551 4.29e-185 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
LKPMBICO_00552 3.52e-70 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
LKPMBICO_00553 7.22e-197 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
LKPMBICO_00554 1.23e-85 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LKPMBICO_00555 2.64e-119 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LKPMBICO_00556 7.97e-206 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LKPMBICO_00557 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LKPMBICO_00559 8.47e-193 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
LKPMBICO_00560 5.78e-249 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
LKPMBICO_00561 2.05e-131 - - - S - - - Psort location CytoplasmicMembrane, score
LKPMBICO_00562 4.08e-79 - - - M - - - Glycosyltransferase like family 2
LKPMBICO_00563 3.24e-94 licD1 - - M ko:K07271 - ko00000,ko01000 LicD family
LKPMBICO_00564 1.23e-67 - - - - - - - -
LKPMBICO_00565 5.83e-117 - - - M - - - transferase activity, transferring glycosyl groups
LKPMBICO_00566 8.8e-84 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
LKPMBICO_00567 1.2e-115 - - - M - - - Core-2/I-Branching enzyme
LKPMBICO_00568 5.3e-47 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKPMBICO_00569 2.29e-81 - - - D - - - Peptidase family M23
LKPMBICO_00571 1.39e-162 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LKPMBICO_00572 5.4e-215 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LKPMBICO_00573 2.26e-130 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LKPMBICO_00574 6.95e-184 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LKPMBICO_00575 1.19e-115 epsE2 - - M - - - Bacterial sugar transferase
LKPMBICO_00576 1.15e-162 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LKPMBICO_00577 4.22e-142 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
LKPMBICO_00578 3.15e-117 ywqD - - D - - - Capsular exopolysaccharide family
LKPMBICO_00579 1.44e-93 epsB - - M - - - biosynthesis protein
LKPMBICO_00580 2.93e-127 - 4.2.1.46 - GM ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Male sterility protein
LKPMBICO_00581 4.64e-124 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
LKPMBICO_00582 2.58e-98 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LKPMBICO_00583 5.83e-131 - - - S - - - Polysaccharide biosynthesis protein
LKPMBICO_00584 7.45e-48 - - - M - - - Capsular polysaccharide synthesis protein
LKPMBICO_00585 8.44e-92 - - - M - - - Glycosyltransferase like family 2
LKPMBICO_00586 4.9e-80 - - GT2 M ko:K12997,ko:K16698 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
LKPMBICO_00587 5.87e-52 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
LKPMBICO_00588 2.92e-67 - - - S - - - Glycosyltransferase family 28 C-terminal domain
LKPMBICO_00589 7.05e-91 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
LKPMBICO_00590 2.22e-11 - - - M - - - Core-2/I-Branching enzyme
LKPMBICO_00591 1.17e-60 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
LKPMBICO_00592 3.88e-66 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
LKPMBICO_00593 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LKPMBICO_00594 2.25e-170 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LKPMBICO_00595 3.94e-56 - - - E - - - GDSL-like Lipase/Acylhydrolase
LKPMBICO_00596 3.91e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_00597 1.15e-239 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LKPMBICO_00598 1.47e-267 potE - - E - - - Amino Acid
LKPMBICO_00599 1.24e-43 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
LKPMBICO_00600 6.02e-173 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
LKPMBICO_00601 2.5e-76 - - - S - - - Glycosyltransferase like family 2
LKPMBICO_00602 4.23e-150 cps3J - - M - - - Domain of unknown function (DUF4422)
LKPMBICO_00603 1.3e-47 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
LKPMBICO_00604 1.51e-113 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
LKPMBICO_00605 1.03e-81 - - - S - - - Haloacid dehalogenase-like hydrolase
LKPMBICO_00606 3.04e-192 - - - EGP - - - Major Facilitator
LKPMBICO_00608 5.73e-90 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LKPMBICO_00609 5.82e-36 adhR - - K - - - transcriptional regulator
LKPMBICO_00610 7.64e-114 - - - S - - - NADPH-dependent FMN reductase
LKPMBICO_00611 7.03e-130 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LKPMBICO_00612 3.99e-71 - - - S - - - ECF transporter, substrate-specific component
LKPMBICO_00613 8.54e-139 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
LKPMBICO_00614 1.6e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LKPMBICO_00615 8.93e-133 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LKPMBICO_00616 2.75e-46 - - - - - - - -
LKPMBICO_00617 3.13e-73 - - - S - - - Protein of unknown function (DUF1129)
LKPMBICO_00618 2.94e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LKPMBICO_00619 3.11e-33 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
LKPMBICO_00620 7.19e-139 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LKPMBICO_00621 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
LKPMBICO_00622 4.35e-104 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LKPMBICO_00623 5.14e-130 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
LKPMBICO_00624 6.73e-161 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LKPMBICO_00625 1.17e-90 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
LKPMBICO_00626 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LKPMBICO_00627 1.36e-78 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
LKPMBICO_00628 7.04e-93 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
LKPMBICO_00630 5.89e-82 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
LKPMBICO_00631 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LKPMBICO_00632 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LKPMBICO_00633 5e-45 - - - - - - - -
LKPMBICO_00634 3.93e-180 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LKPMBICO_00635 2.46e-198 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LKPMBICO_00636 4.49e-123 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LKPMBICO_00637 1.64e-198 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LKPMBICO_00638 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
LKPMBICO_00640 5.43e-122 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_00641 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
LKPMBICO_00642 4.92e-235 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
LKPMBICO_00643 1.63e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKPMBICO_00644 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LKPMBICO_00645 6.4e-138 - - - P - - - Integral membrane protein TerC family
LKPMBICO_00646 3.75e-49 - - - K - - - Transcriptional regulator
LKPMBICO_00647 3.36e-122 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LKPMBICO_00648 7.11e-129 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_00649 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKPMBICO_00650 1.66e-51 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LKPMBICO_00651 1.01e-236 noxE - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LKPMBICO_00652 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LKPMBICO_00653 2.7e-258 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
LKPMBICO_00654 2.84e-220 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
LKPMBICO_00655 3.08e-135 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LKPMBICO_00656 4.88e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
LKPMBICO_00657 2.82e-88 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
LKPMBICO_00658 2.16e-192 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
LKPMBICO_00659 5.15e-145 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
LKPMBICO_00660 8.21e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
LKPMBICO_00661 1.23e-265 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LKPMBICO_00663 5.69e-142 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
LKPMBICO_00664 1.85e-96 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
LKPMBICO_00665 2.17e-240 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
LKPMBICO_00666 1.89e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
LKPMBICO_00667 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
LKPMBICO_00668 9.99e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
LKPMBICO_00669 3.96e-76 - - - F - - - Nucleoside 2-deoxyribosyltransferase
LKPMBICO_00670 6.95e-97 azlC - - E - - - branched-chain amino acid
LKPMBICO_00671 1.46e-42 - - - S - - - Branched-chain amino acid transport protein (AzlD)
LKPMBICO_00672 2.21e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKPMBICO_00673 5.51e-71 jag - - S ko:K06346 - ko00000 R3H domain protein
LKPMBICO_00674 2.59e-150 - - - L - - - Belongs to the 'phage' integrase family
LKPMBICO_00677 3.63e-52 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
LKPMBICO_00682 3.63e-24 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
LKPMBICO_00686 7.64e-185 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LKPMBICO_00687 4.48e-270 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LKPMBICO_00688 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKPMBICO_00689 6.83e-230 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LKPMBICO_00690 1.2e-144 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
LKPMBICO_00691 1.53e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
LKPMBICO_00692 1.43e-67 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
LKPMBICO_00693 3.27e-17 - - - M - - - Glycosyl transferase family 2
LKPMBICO_00694 5.71e-28 - - - - - - - -
LKPMBICO_00695 1.39e-110 - - - S - - - Predicted membrane protein (DUF2207)
LKPMBICO_00696 1.34e-71 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LKPMBICO_00697 4.05e-227 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
LKPMBICO_00698 1.34e-116 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LKPMBICO_00699 1.13e-91 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LKPMBICO_00700 3.38e-74 yceE - - S - - - haloacid dehalogenase-like hydrolase
LKPMBICO_00701 7.95e-42 - - - S - - - Domain of unknown function (DUF4811)
LKPMBICO_00702 4.67e-245 ycnB - - U - - - Belongs to the major facilitator superfamily
LKPMBICO_00703 1.24e-43 - - - K - - - MerR HTH family regulatory protein
LKPMBICO_00704 9.06e-52 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKPMBICO_00705 1.22e-89 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LKPMBICO_00706 8.41e-148 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LKPMBICO_00707 1.51e-101 yfiK - - K ko:K02479 - ko00000,ko02022 Bacterial regulatory proteins, luxR family
LKPMBICO_00708 3.34e-122 baeS - - T - - - Histidine kinase
LKPMBICO_00709 2.68e-102 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
LKPMBICO_00710 1.84e-191 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LKPMBICO_00711 4.84e-153 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
LKPMBICO_00712 1.4e-188 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
LKPMBICO_00713 7.96e-68 - - - S - - - Domain of unknown function (DUF956)
LKPMBICO_00714 4.25e-92 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
LKPMBICO_00715 4.1e-164 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LKPMBICO_00716 1.19e-208 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKPMBICO_00717 1.36e-96 ung2 - - L - - - Uracil-DNA glycosylase
LKPMBICO_00718 3.61e-43 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LKPMBICO_00719 1.03e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
LKPMBICO_00720 1.29e-28 - - - S - - - Protein of unknown function (DUF1700)
LKPMBICO_00721 3.71e-09 - - - S - - - Putative adhesin
LKPMBICO_00722 1.6e-78 - - - L - - - Resolvase, N-terminal domain
LKPMBICO_00723 1.45e-120 - - - L - - - Probable transposase
LKPMBICO_00724 1.24e-21 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LKPMBICO_00727 4.13e-296 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LKPMBICO_00728 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
LKPMBICO_00729 3.27e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LKPMBICO_00730 4.46e-212 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LKPMBICO_00731 3.85e-153 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LKPMBICO_00732 3.11e-133 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKPMBICO_00733 1.19e-201 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKPMBICO_00734 5.57e-169 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LKPMBICO_00735 1.96e-146 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LKPMBICO_00736 2.44e-139 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_00737 1.17e-85 yciB - - M - - - ErfK YbiS YcfS YnhG
LKPMBICO_00738 9.35e-70 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LKPMBICO_00739 6.13e-286 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LKPMBICO_00740 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LKPMBICO_00741 2.22e-131 pgm3 - - G - - - phosphoglycerate mutase
LKPMBICO_00742 5.8e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LKPMBICO_00743 4.46e-62 - - - C - - - Flavodoxin
LKPMBICO_00744 1.38e-74 yphH - - S - - - Cupin domain
LKPMBICO_00745 1.03e-59 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
LKPMBICO_00746 5.08e-178 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
LKPMBICO_00747 2.56e-136 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LKPMBICO_00748 2.65e-188 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LKPMBICO_00749 5.23e-119 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LKPMBICO_00750 3.22e-168 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
LKPMBICO_00751 9.46e-106 - - - C - - - nitroreductase
LKPMBICO_00752 2.17e-106 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
LKPMBICO_00753 4.72e-136 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
LKPMBICO_00754 4.96e-213 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LKPMBICO_00755 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
LKPMBICO_00757 1.53e-192 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LKPMBICO_00758 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LKPMBICO_00759 3.63e-163 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LKPMBICO_00760 4.02e-75 - - - S - - - Protein of unknown function (DUF4256)
LKPMBICO_00762 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
LKPMBICO_00763 1.49e-223 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
LKPMBICO_00764 7.47e-213 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
LKPMBICO_00765 2.22e-229 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKPMBICO_00766 4.17e-289 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
LKPMBICO_00767 2.72e-186 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LKPMBICO_00768 3.45e-70 - - - S - - - Protein of unknown function (DUF975)
LKPMBICO_00769 3.47e-79 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LKPMBICO_00770 3.57e-17 - - - - - - - -
LKPMBICO_00771 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
LKPMBICO_00772 3.25e-280 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
LKPMBICO_00773 1.2e-112 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
LKPMBICO_00774 4.7e-192 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LKPMBICO_00775 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
LKPMBICO_00776 3.27e-57 cps3F - - - - - - -
LKPMBICO_00777 2.22e-108 - - - S - - - Membrane
LKPMBICO_00778 0.0 - - - E - - - Amino acid permease
LKPMBICO_00779 1.46e-292 cadA - - P - - - P-type ATPase
LKPMBICO_00780 5.8e-145 degV - - S - - - EDD domain protein, DegV family
LKPMBICO_00781 8.33e-189 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
LKPMBICO_00782 1.18e-69 - - - F - - - glutamine amidotransferase
LKPMBICO_00783 1.67e-35 yuxO - - Q - - - Thioesterase superfamily
LKPMBICO_00784 6.07e-186 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LKPMBICO_00785 1.04e-171 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LKPMBICO_00786 6.81e-103 - - - S - - - L,D-transpeptidase catalytic domain
LKPMBICO_00787 2.05e-208 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
LKPMBICO_00788 8.04e-21 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKPMBICO_00789 6.3e-286 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LKPMBICO_00790 1.2e-147 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LKPMBICO_00791 1.39e-42 - - - S - - - Protein of unknown function (DUF1634)
LKPMBICO_00792 3.86e-154 - - - S ko:K07090 - ko00000 membrane transporter protein
LKPMBICO_00793 1.91e-106 lysR5 - - K - - - LysR substrate binding domain
LKPMBICO_00794 1.51e-71 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
LKPMBICO_00795 2.9e-14 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LKPMBICO_00796 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LKPMBICO_00797 1.12e-86 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LKPMBICO_00798 2.64e-308 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
LKPMBICO_00799 7.95e-263 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LKPMBICO_00801 2.61e-67 - - - K - - - Transcriptional regulator C-terminal region
LKPMBICO_00802 2.5e-59 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
LKPMBICO_00803 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LKPMBICO_00804 7.86e-140 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
LKPMBICO_00806 5.83e-86 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
LKPMBICO_00807 1.37e-61 hmpT - - S - - - ECF-type riboflavin transporter, S component
LKPMBICO_00808 2.78e-54 - - - K - - - Acetyltransferase GNAT Family
LKPMBICO_00810 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LKPMBICO_00811 8.17e-123 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_00812 9.01e-42 tetR - - K - - - transcriptional regulator
LKPMBICO_00814 5.37e-45 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKPMBICO_00815 1.04e-34 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKPMBICO_00816 6.38e-152 ytbE - - S - - - reductase
LKPMBICO_00817 1.22e-57 ytcD - - K - - - HxlR-like helix-turn-helix
LKPMBICO_00818 1.25e-130 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
LKPMBICO_00819 8.31e-87 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
LKPMBICO_00820 5.28e-94 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
LKPMBICO_00821 1.49e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
LKPMBICO_00822 5.58e-69 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LKPMBICO_00823 2.53e-60 - - - S - - - Short repeat of unknown function (DUF308)
LKPMBICO_00824 4.63e-30 - - - K - - - Transcriptional regulator C-terminal region
LKPMBICO_00825 2.6e-191 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
LKPMBICO_00827 2.35e-51 - - - K - - - LytTr DNA-binding domain
LKPMBICO_00828 5.63e-146 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
LKPMBICO_00829 2.36e-265 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LKPMBICO_00830 1.85e-21 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
LKPMBICO_00831 2.43e-197 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKPMBICO_00832 3.5e-229 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKPMBICO_00833 7.43e-217 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKPMBICO_00834 3.98e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKPMBICO_00835 2.51e-253 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LKPMBICO_00836 2.51e-276 yifK - - E ko:K03293 - ko00000 Amino acid permease
LKPMBICO_00837 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LKPMBICO_00838 1.09e-72 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
LKPMBICO_00839 2.19e-81 pgm3 - - G - - - phosphoglycerate mutase
LKPMBICO_00840 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LKPMBICO_00841 1.21e-25 - - - S - - - Cupredoxin-like domain
LKPMBICO_00842 1.22e-55 - - - S - - - Cupredoxin-like domain
LKPMBICO_00843 1.38e-29 - - - K - - - Transcriptional regulator, ArsR family
LKPMBICO_00844 3.75e-98 - - - S - - - intracellular protease amidase
LKPMBICO_00845 4.65e-171 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
LKPMBICO_00846 1.92e-101 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
LKPMBICO_00847 5.9e-178 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LKPMBICO_00848 6.91e-254 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
LKPMBICO_00849 3.59e-149 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LKPMBICO_00850 1.54e-243 - - - C - - - FMN_bind
LKPMBICO_00851 1.6e-70 oxyR5 - - K - - - Transcriptional regulator
LKPMBICO_00852 1.8e-203 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LKPMBICO_00853 1.46e-249 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
LKPMBICO_00854 2.83e-93 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
LKPMBICO_00855 1.58e-167 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
LKPMBICO_00856 5.93e-128 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LKPMBICO_00857 7.73e-105 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
LKPMBICO_00858 3.84e-12 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
LKPMBICO_00859 3.46e-78 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
LKPMBICO_00860 1.22e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LKPMBICO_00862 2.03e-291 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LKPMBICO_00863 3.42e-82 - - - C - - - FMN binding
LKPMBICO_00864 1.02e-259 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LKPMBICO_00865 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LKPMBICO_00866 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LKPMBICO_00871 7.65e-258 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LKPMBICO_00872 2.03e-126 - - - GKT - - - COG3711 Transcriptional antiterminator
LKPMBICO_00873 3.21e-43 - 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 to PTS fructose-specific enzyme IIA component
LKPMBICO_00874 5.58e-43 - - - G - - - PTS system, Lactose/Cellobiose specific IIB subunit
LKPMBICO_00875 3.61e-245 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LKPMBICO_00876 1.25e-148 - - - E - - - Alcohol dehydrogenase GroES-like domain
LKPMBICO_00877 2e-120 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
LKPMBICO_00879 2.15e-96 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LKPMBICO_00880 2.28e-112 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LKPMBICO_00881 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LKPMBICO_00882 1.9e-131 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
LKPMBICO_00884 4.77e-74 - - - S - - - COG NOG19168 non supervised orthologous group
LKPMBICO_00885 1.43e-240 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
LKPMBICO_00887 2.61e-84 - - - L - - - Belongs to the 'phage' integrase family
LKPMBICO_00888 1.22e-35 - - - L - - - Belongs to the 'phage' integrase family
LKPMBICO_00890 4.27e-63 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LKPMBICO_00892 1.11e-20 - - - L - - - T/G mismatch-specific endonuclease activity
LKPMBICO_00893 1.99e-128 - - - I - - - PLD-like domain
LKPMBICO_00894 0.0 - - - V - - - DNA restriction-modification system
LKPMBICO_00895 0.0 - - - L - - - helicase superfamily c-terminal domain
LKPMBICO_00897 2.86e-14 - - - - - - - -
LKPMBICO_00900 3.88e-215 potE2 - - E ko:K03294 - ko00000 amino acid
LKPMBICO_00901 2.73e-185 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
LKPMBICO_00902 1.11e-147 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LKPMBICO_00903 6.54e-75 - - - K - - - Domain of unknown function (DUF1836)
LKPMBICO_00904 2.66e-101 yitS - - S - - - EDD domain protein, DegV family
LKPMBICO_00905 3.77e-57 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LKPMBICO_00907 1.73e-49 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LKPMBICO_00908 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LKPMBICO_00909 1.23e-34 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
LKPMBICO_00910 1.31e-91 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
LKPMBICO_00911 1.73e-157 - - - - - - - -
LKPMBICO_00912 1.52e-84 - - - L ko:K07491 - ko00000 Transposase IS200 like
LKPMBICO_00913 6.48e-35 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
LKPMBICO_00914 1.22e-66 - - - C - - - Oxidoreductase NAD-binding domain
LKPMBICO_00915 3.59e-84 - - - L - - - Probable transposase
LKPMBICO_00916 1.41e-106 - - - C - - - Domain of unknown function (DUF4931)
LKPMBICO_00917 2.6e-114 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
LKPMBICO_00918 1.8e-67 - - - M - - - LysM domain protein
LKPMBICO_00919 1.38e-25 - - - P - - - Rhodanese Homology Domain
LKPMBICO_00920 8.48e-48 - - - M - - - LysM domain
LKPMBICO_00921 2.32e-203 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
LKPMBICO_00922 1.84e-244 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
LKPMBICO_00923 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
LKPMBICO_00924 1.09e-253 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LKPMBICO_00925 4.93e-276 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
LKPMBICO_00926 4.59e-121 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LKPMBICO_00927 1.41e-133 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
LKPMBICO_00928 6.22e-197 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LKPMBICO_00929 6.76e-181 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
LKPMBICO_00930 1.13e-17 - - - T - - - diguanylate cyclase
LKPMBICO_00931 4.55e-162 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
LKPMBICO_00932 8.88e-236 - - - - - - - -
LKPMBICO_00933 1.48e-256 - - - S - - - Protein conserved in bacteria
LKPMBICO_00934 2.45e-255 ydaM - - M - - - Glycosyl transferase family group 2
LKPMBICO_00935 0.0 - - - S - - - Bacterial cellulose synthase subunit
LKPMBICO_00936 4.61e-153 - - - T - - - diguanylate cyclase activity
LKPMBICO_00937 8.48e-37 - - - T - - - Putative diguanylate phosphodiesterase
LKPMBICO_00938 5.2e-77 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LKPMBICO_00939 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LKPMBICO_00940 1.93e-69 - - - S - - - Membrane
LKPMBICO_00941 7.32e-81 - - - K - - - helix_turn_helix, arabinose operon control protein
LKPMBICO_00943 4.56e-266 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LKPMBICO_00944 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
LKPMBICO_00945 2.82e-240 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LKPMBICO_00946 3.9e-78 yokL3 - - J - - - Acetyltransferase (GNAT) domain
LKPMBICO_00947 3.53e-144 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LKPMBICO_00948 2.26e-105 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LKPMBICO_00949 7.76e-82 - - - - - - - -
LKPMBICO_00950 2.78e-224 rsmF - - J - - - NOL1 NOP2 sun family protein
LKPMBICO_00951 1.21e-52 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Protease synthase and sporulation negative regulatory protein pai 1
LKPMBICO_00952 0.000127 - - - M - - - Glycosyl transferases group 1
LKPMBICO_00954 4.86e-106 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
LKPMBICO_00955 2.54e-53 ywnA - - K - - - Transcriptional regulator
LKPMBICO_00956 2.45e-41 - - - S - - - CHY zinc finger
LKPMBICO_00957 1.69e-17 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
LKPMBICO_00958 1.55e-68 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
LKPMBICO_00960 2.29e-51 ybbB - - S - - - Protein of unknown function (DUF1211)
LKPMBICO_00961 4.47e-29 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
LKPMBICO_00963 3.92e-52 - - - M - - - Acetyltransferase (GNAT) family
LKPMBICO_00964 4.12e-91 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
LKPMBICO_00965 2.53e-79 - - - H - - - Methyltransferase domain
LKPMBICO_00971 1.06e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
LKPMBICO_00972 1.29e-200 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LKPMBICO_00973 4.01e-44 - - - P - - - Heavy-metal-associated domain
LKPMBICO_00974 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
LKPMBICO_00975 3.67e-21 - - - L - - - An automated process has identified a potential problem with this gene model
LKPMBICO_00976 1.83e-50 - - - L - - - An automated process has identified a potential problem with this gene model
LKPMBICO_00977 2.42e-28 - - - L ko:K07483 - ko00000 PFAM transposase IS3 IS911 family protein
LKPMBICO_00978 8.85e-107 - - - L ko:K07497 - ko00000 Integrase core domain
LKPMBICO_00979 7.6e-168 - - - EGP - - - Major Facilitator Superfamily
LKPMBICO_00980 7.05e-123 - - - EGP - - - Major Facilitator Superfamily
LKPMBICO_00981 4.01e-91 - - - K - - - Transcriptional regulator, LysR family
LKPMBICO_00982 4.28e-176 - - - G - - - Xylose isomerase-like TIM barrel
LKPMBICO_00983 1.73e-148 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LKPMBICO_00984 4.85e-270 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LKPMBICO_00985 2.97e-175 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LKPMBICO_00986 8.35e-90 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LKPMBICO_00987 5.14e-180 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
LKPMBICO_00991 4.89e-129 bsh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LKPMBICO_00992 1.85e-89 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LKPMBICO_00993 7.64e-73 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
LKPMBICO_00994 8.62e-73 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKPMBICO_00995 7.81e-67 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LKPMBICO_00996 6.88e-100 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LKPMBICO_00997 6.66e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LKPMBICO_00998 5e-100 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LKPMBICO_00999 3.71e-21 - - - - - - - -
LKPMBICO_01000 6.83e-77 - - - V - - - endonuclease activity
LKPMBICO_01001 1.14e-71 - - - L - - - Belongs to the 'phage' integrase family
LKPMBICO_01005 9.79e-35 - - - M - - - CHAP domain
LKPMBICO_01007 1.82e-234 - - - U - - - type IV secretory pathway VirB4
LKPMBICO_01010 7.14e-85 - - - - - - - -
LKPMBICO_01011 2.82e-265 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
LKPMBICO_01015 1.98e-180 - - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LKPMBICO_01018 5.37e-201 topA2 5.99.1.2 - G ko:K03169 - ko00000,ko01000,ko03032 Topoisomerase IA
LKPMBICO_01019 5.83e-25 - - - L - - - Protein of unknown function (DUF3991)
LKPMBICO_01020 1.53e-73 - - - - - - - -
LKPMBICO_01022 1.75e-26 - - - S - - - PIN domain
LKPMBICO_01023 1.43e-07 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
LKPMBICO_01024 2.33e-95 - - - DM - - - Glucan-binding protein C
LKPMBICO_01025 2.45e-08 pac - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LKPMBICO_01026 4.05e-134 - - - L - - - Belongs to the 'phage' integrase family
LKPMBICO_01027 4.07e-69 - - - S - - - Fic/DOC family
LKPMBICO_01028 3.87e-190 - - - K - - - IrrE N-terminal-like domain
LKPMBICO_01029 2.18e-90 - - - - - - - -
LKPMBICO_01031 3.52e-87 - - - D - - - nuclear chromosome segregation
LKPMBICO_01032 1.05e-08 - - - K - - - sequence-specific DNA binding
LKPMBICO_01033 5.24e-100 - - - S - - - Fic/DOC family
LKPMBICO_01037 1.02e-38 - - - L - - - four-way junction helicase activity
LKPMBICO_01041 2.06e-11 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
LKPMBICO_01057 1.86e-20 - 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Peptidase S24-like
LKPMBICO_01060 6.76e-05 - - - - - - - -
LKPMBICO_01061 3.77e-104 - - - L - - - DNA restriction-modification system
LKPMBICO_01064 1.19e-80 - - - L - - - ISXO2-like transposase domain
LKPMBICO_01065 3.78e-110 - - - S - - - Fic/DOC family
LKPMBICO_01066 5.37e-176 - - - L ko:K07497 - ko00000 Integrase core domain
LKPMBICO_01067 2.4e-89 - - - K - - - Domain of unknown function (DUF1836)
LKPMBICO_01070 2.46e-07 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LKPMBICO_01073 1.08e-38 - - - - - - - -
LKPMBICO_01075 3.76e-18 - - - - - - - -
LKPMBICO_01076 2.5e-140 rssA - - S - - - Phospholipase, patatin family
LKPMBICO_01077 5.49e-175 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LKPMBICO_01078 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
LKPMBICO_01079 6.68e-64 - - - S - - - VIT family
LKPMBICO_01080 9.19e-304 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
LKPMBICO_01081 1.15e-53 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
LKPMBICO_01082 1.39e-182 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LKPMBICO_01083 9.15e-181 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
LKPMBICO_01084 1.5e-147 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
LKPMBICO_01085 4.47e-281 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LKPMBICO_01087 1.48e-33 - - - K - - - Helix-turn-helix XRE-family like proteins
LKPMBICO_01088 3.19e-114 - - - L - - - Probable transposase
LKPMBICO_01089 8.66e-92 - - - L - - - Probable transposase
LKPMBICO_01090 7.03e-12 - - - L - - - Probable transposase
LKPMBICO_01093 1.35e-47 - - - S - - - sequence-specific DNA binding
LKPMBICO_01095 5.9e-27 - - - - - - - -
LKPMBICO_01096 1.1e-172 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LKPMBICO_01097 3.14e-147 ddh 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKPMBICO_01098 4.7e-82 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
LKPMBICO_01099 2.21e-47 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LKPMBICO_01100 2.69e-173 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
LKPMBICO_01101 1.93e-106 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
LKPMBICO_01102 7.01e-57 srlM1 - - K - - - Glucitol operon activator protein (GutM)
LKPMBICO_01103 1.01e-93 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LKPMBICO_01104 1.37e-140 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
LKPMBICO_01105 2.11e-135 ytbD - - EGP ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
LKPMBICO_01106 1.68e-127 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
LKPMBICO_01107 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
LKPMBICO_01109 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
LKPMBICO_01110 8.56e-90 - - - L - - - Phage integrase, N-terminal SAM-like domain
LKPMBICO_01112 1.47e-113 - - - S - - - Haloacid dehalogenase-like hydrolase
LKPMBICO_01113 1.35e-17 - - - - - - - -
LKPMBICO_01114 3.46e-19 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
LKPMBICO_01115 3.95e-37 - - - S - - - Phage gp6-like head-tail connector protein
LKPMBICO_01116 7.77e-122 - - - - - - - -
LKPMBICO_01117 1.89e-16 - - - S - - - Domain of unknown function (DUF4355)
LKPMBICO_01123 9.73e-65 - - - S - - - Phage Mu protein F like protein
LKPMBICO_01124 1.15e-236 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LKPMBICO_01125 9.31e-103 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
LKPMBICO_01126 3.93e-87 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
LKPMBICO_01127 5.79e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
LKPMBICO_01128 1.05e-143 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LKPMBICO_01129 4.48e-95 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
LKPMBICO_01130 1.02e-259 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKPMBICO_01131 1.63e-193 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LKPMBICO_01132 1.51e-81 - - - G - - - Xylose isomerase domain protein TIM barrel
LKPMBICO_01133 4.37e-70 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
LKPMBICO_01134 2.9e-114 nanK - - GK - - - ROK family
LKPMBICO_01135 4.39e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
LKPMBICO_01136 5.09e-118 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LKPMBICO_01137 8.17e-96 - - - K - - - Helix-turn-helix domain, rpiR family
LKPMBICO_01138 7.43e-80 yphA - - GM - - - NAD dependent epimerase/dehydratase family
LKPMBICO_01139 6.19e-271 potE - - E - - - Amino Acid
LKPMBICO_01140 5.75e-09 - - - - - - - -
LKPMBICO_01141 5.44e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKPMBICO_01142 2.87e-289 fusA1 - - J - - - elongation factor G
LKPMBICO_01143 2.87e-98 - - - S - - - Fic/DOC family
LKPMBICO_01144 1.6e-219 - - - L - - - PLD-like domain
LKPMBICO_01147 3.24e-142 - - - L - - - Initiator Replication protein
LKPMBICO_01148 1.88e-45 - - - S - - - Replication initiator protein A (RepA) N-terminus
LKPMBICO_01149 3.44e-215 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LKPMBICO_01150 1.32e-256 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Pts system
LKPMBICO_01151 1.91e-87 licT - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LKPMBICO_01152 2.27e-161 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
LKPMBICO_01154 5.14e-46 - - - - - - - -
LKPMBICO_01155 4.56e-07 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
LKPMBICO_01156 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
LKPMBICO_01157 1.06e-53 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
LKPMBICO_01159 3.39e-19 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LKPMBICO_01161 1.53e-159 yvgN - - C - - - Aldo keto reductase
LKPMBICO_01162 6.75e-132 - - - S ko:K07089 - ko00000 Predicted permease
LKPMBICO_01163 1.21e-80 - - - S - - - Sulphur transport
LKPMBICO_01164 1.67e-14 - - - O - - - the current gene model (or a revised gene model) may contain a frame shift
LKPMBICO_01165 2.38e-148 - - - P - - - Rhodanese Homology Domain
LKPMBICO_01167 2.06e-292 prdA 1.21.4.1 - EJ ko:K10793 ko00330,map00330 ko00000,ko00001,ko01000 Glycine/sarcosine/betaine reductase component B subunits
LKPMBICO_01168 1.57e-34 - - - S - - - Psort location Cytoplasmic, score
LKPMBICO_01169 1.14e-84 prdB - - S - - - the current gene model (or a revised gene model) may contain a premature stop
LKPMBICO_01170 2.69e-42 - - - S - - - the current gene model (or a revised gene model) may contain a premature stop
LKPMBICO_01171 1.95e-90 - - - S - - - An automated process has identified a potential problem with this gene model
LKPMBICO_01172 6.97e-87 - - - EJ - - - Glycine/sarcosine/betaine reductase component B subunits
LKPMBICO_01173 2.59e-183 - 5.1.1.4 - E ko:K01777 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Proline racemase
LKPMBICO_01174 1.37e-123 - - - S - - - Sulfite exporter TauE/SafE
LKPMBICO_01175 1.53e-280 - - - E - - - amino acid
LKPMBICO_01176 2.48e-61 yedF - - O - - - Belongs to the sulfur carrier protein TusA family
LKPMBICO_01178 5.94e-167 selB - - J ko:K03833 - ko00000,ko03012 Elongation factor SelB, winged helix
LKPMBICO_01179 1.19e-138 - - - E - - - Serine hydroxymethyltransferase
LKPMBICO_01180 1.12e-142 selA 2.9.1.1 - J ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
LKPMBICO_01181 7.55e-38 - - - S - - - Iron-sulfur cluster assembly protein
LKPMBICO_01182 1.33e-236 - - - C - - - RnfC Barrel sandwich hybrid domain
LKPMBICO_01183 7.18e-126 selD 2.7.9.3 - E ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 Synthesizes selenophosphate from selenide and ATP
LKPMBICO_01184 1.31e-187 - - - S ko:K07112 - ko00000 Sulphur transport
LKPMBICO_01185 2.1e-38 - - - O - - - Belongs to the sulfur carrier protein TusA family
LKPMBICO_01195 4.84e-166 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LKPMBICO_01196 1.53e-234 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LKPMBICO_01197 2.75e-199 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LKPMBICO_01198 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LKPMBICO_01199 2.86e-150 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LKPMBICO_01201 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LKPMBICO_01202 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LKPMBICO_01203 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKPMBICO_01204 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKPMBICO_01205 3.15e-29 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
LKPMBICO_01206 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LKPMBICO_01207 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LKPMBICO_01208 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LKPMBICO_01209 3.83e-116 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LKPMBICO_01210 2.23e-105 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LKPMBICO_01211 1.21e-145 vanR - - K - - - response regulator
LKPMBICO_01212 5.29e-191 hpk31 - - T - - - Histidine kinase
LKPMBICO_01213 1.02e-113 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LKPMBICO_01214 9.14e-187 - - - G - - - Transporter, major facilitator family protein
LKPMBICO_01215 3.86e-278 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LKPMBICO_01216 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_01217 4.44e-44 - - - K - - - Bacterial regulatory proteins, tetR family
LKPMBICO_01218 1.87e-279 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_01219 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
LKPMBICO_01220 1.29e-11 - - - - - - - -
LKPMBICO_01221 5.29e-59 yyaT - - K ko:K02348 - ko00000 protein acetylation
LKPMBICO_01222 1.34e-66 ymdB - - L - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
LKPMBICO_01223 2.31e-94 lemA - - S ko:K03744 - ko00000 LemA family
LKPMBICO_01224 1.77e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LKPMBICO_01226 0.0 - - - L - - - DNA helicase
LKPMBICO_01227 2.75e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKPMBICO_01228 2.82e-217 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LKPMBICO_01229 5.61e-129 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LKPMBICO_01230 7.83e-106 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
LKPMBICO_01231 6.39e-131 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LKPMBICO_01232 7.61e-40 - - - K - - - Bacterial regulatory proteins, tetR family
LKPMBICO_01233 4.2e-54 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
LKPMBICO_01234 1.08e-190 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
LKPMBICO_01235 3.93e-163 - - - - - - - -
LKPMBICO_01236 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LKPMBICO_01237 5.15e-133 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
LKPMBICO_01238 4.87e-112 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LKPMBICO_01239 5.37e-169 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LKPMBICO_01240 1.9e-31 veg - - S - - - Biofilm formation stimulator VEG
LKPMBICO_01241 2.69e-115 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LKPMBICO_01242 1.93e-171 arcT - - E - - - Cys/Met metabolism PLP-dependent enzyme
LKPMBICO_01243 5.91e-61 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LKPMBICO_01244 3.59e-148 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LKPMBICO_01245 1.49e-193 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
LKPMBICO_01246 9.57e-254 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LKPMBICO_01247 6.51e-248 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LKPMBICO_01248 2.01e-189 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LKPMBICO_01249 5.68e-159 - 1.1.1.28 - C ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKPMBICO_01250 1.02e-138 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LKPMBICO_01251 6.82e-235 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LKPMBICO_01252 8.77e-37 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LKPMBICO_01253 7.37e-175 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LKPMBICO_01254 4.71e-18 - - - EGP - - - Transmembrane secretion effector
LKPMBICO_01255 2.8e-30 - - - EGP - - - Transmembrane secretion effector
LKPMBICO_01256 1.95e-257 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LKPMBICO_01257 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LKPMBICO_01258 9.85e-27 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LKPMBICO_01259 6.77e-140 dkgB - - S - - - reductase
LKPMBICO_01260 1.82e-33 - - - - - - - -
LKPMBICO_01261 3.22e-98 - - - F - - - Phosphorylase superfamily
LKPMBICO_01262 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
LKPMBICO_01263 1.43e-79 ytkL - - S - - - Belongs to the UPF0173 family
LKPMBICO_01264 1.23e-124 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LKPMBICO_01265 4.53e-156 yibE - - S - - - overlaps another CDS with the same product name
LKPMBICO_01266 4.73e-110 - - - S - - - overlaps another CDS with the same product name
LKPMBICO_01268 3.19e-61 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
LKPMBICO_01270 8.59e-25 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 PIF1-like helicase
LKPMBICO_01272 3.26e-73 - - - - - - - -
LKPMBICO_01273 7.65e-17 - - - - - - - -
LKPMBICO_01274 2.02e-130 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
LKPMBICO_01275 4.33e-112 - - - S - - - hydrolase
LKPMBICO_01276 1.2e-261 ywfO - - S ko:K06885 - ko00000 HD domain protein
LKPMBICO_01277 1.42e-109 - - - F - - - glutamine amidotransferase
LKPMBICO_01278 1.8e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
LKPMBICO_01279 3.51e-57 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LKPMBICO_01280 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LKPMBICO_01283 1.47e-251 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LKPMBICO_01284 1.93e-240 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LKPMBICO_01285 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LKPMBICO_01286 5.23e-78 - - - - - - - -
LKPMBICO_01287 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
LKPMBICO_01289 1.94e-100 - - - S - - - Cell surface protein
LKPMBICO_01291 1.43e-229 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LKPMBICO_01292 1.54e-81 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
LKPMBICO_01293 3.29e-224 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LKPMBICO_01294 1.87e-282 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LKPMBICO_01295 1.5e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LKPMBICO_01296 7.6e-182 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKPMBICO_01298 5e-64 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LKPMBICO_01299 4.29e-115 yunF - - F - - - Protein of unknown function DUF72
LKPMBICO_01300 6.62e-196 yngD - - S ko:K07097 - ko00000 DHHA1 domain
LKPMBICO_01301 1.8e-56 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
LKPMBICO_01302 5.45e-73 - - - - - - - -
LKPMBICO_01303 1.5e-52 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LKPMBICO_01304 3.16e-30 - - - S - - - Cytochrome B5
LKPMBICO_01306 7.72e-80 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
LKPMBICO_01307 9.06e-151 - - - L - - - Belongs to the 'phage' integrase family
LKPMBICO_01308 1.31e-14 ansR - - K - - - Transcriptional regulator
LKPMBICO_01310 2.55e-37 - - - K - - - COG3617 Prophage antirepressor
LKPMBICO_01315 3.65e-26 - - - - - - - -
LKPMBICO_01317 8.65e-49 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
LKPMBICO_01320 8.99e-242 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKPMBICO_01321 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LKPMBICO_01322 2.02e-135 yueF - - S - - - AI-2E family transporter
LKPMBICO_01323 2.2e-200 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LKPMBICO_01324 9.84e-147 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LKPMBICO_01325 3.3e-134 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LKPMBICO_01326 4.37e-181 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LKPMBICO_01327 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
LKPMBICO_01328 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LKPMBICO_01329 1.84e-138 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LKPMBICO_01330 4.34e-225 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LKPMBICO_01331 1.8e-207 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LKPMBICO_01332 1.72e-252 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LKPMBICO_01333 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LKPMBICO_01334 4.68e-131 - - - G - - - MucBP domain
LKPMBICO_01335 3.55e-31 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
LKPMBICO_01336 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
LKPMBICO_01337 1.5e-22 - - - - - - - -
LKPMBICO_01338 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
LKPMBICO_01339 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LKPMBICO_01340 6.31e-204 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LKPMBICO_01341 7.47e-163 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LKPMBICO_01342 3.57e-165 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LKPMBICO_01343 3.45e-36 ykuJ - - S - - - Protein of unknown function (DUF1797)
LKPMBICO_01344 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LKPMBICO_01348 3.19e-59 tnpR1 - - L - - - Resolvase, N terminal domain
LKPMBICO_01353 7.8e-26 - - - - - - - -
LKPMBICO_01357 3.36e-18 - - - M - - - hydrolase, family 25
LKPMBICO_01358 6.01e-33 nicK - - L ko:K07467 - ko00000 Replication initiation factor
LKPMBICO_01359 4.75e-05 nicK - - L ko:K07467 - ko00000 Replication initiation factor
LKPMBICO_01363 1.37e-65 - - - L - - - Protein involved in initiation of plasmid replication
LKPMBICO_01367 1.25e-273 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
LKPMBICO_01368 1.53e-61 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LKPMBICO_01369 1.87e-85 coiA - - S ko:K06198 - ko00000 Competence protein
LKPMBICO_01370 1.76e-288 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LKPMBICO_01371 1.01e-53 yjbH - - Q - - - Thioredoxin
LKPMBICO_01372 1.07e-125 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LKPMBICO_01373 2.58e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LKPMBICO_01374 1.35e-154 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
LKPMBICO_01375 7.48e-147 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKPMBICO_01376 5.27e-148 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKPMBICO_01377 6.44e-73 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
LKPMBICO_01378 1.21e-188 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
LKPMBICO_01379 1.39e-100 - - - S - - - VIT family
LKPMBICO_01380 2.71e-107 - - - S - - - membrane
LKPMBICO_01381 1.97e-53 - - - K - - - Domain of unknown function (DUF1836)
LKPMBICO_01382 8.68e-83 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
LKPMBICO_01383 3.39e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LKPMBICO_01384 3.43e-96 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKPMBICO_01386 2.23e-10 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LKPMBICO_01388 9.17e-219 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LKPMBICO_01389 1.79e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LKPMBICO_01390 4.81e-54 - - - S - - - VanZ like family
LKPMBICO_01391 4e-153 yebC - - K - - - Transcriptional regulatory protein
LKPMBICO_01392 1.16e-129 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LKPMBICO_01393 2.24e-152 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
LKPMBICO_01394 7.88e-122 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
LKPMBICO_01395 4.34e-36 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
LKPMBICO_01396 7.13e-18 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
LKPMBICO_01400 1.41e-123 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
LKPMBICO_01401 3.13e-239 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LKPMBICO_01402 9.2e-73 - - - S - - - Calcineurin-like phosphoesterase
LKPMBICO_01403 4.29e-77 yutD - - S - - - Protein of unknown function (DUF1027)
LKPMBICO_01404 1.19e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LKPMBICO_01405 4.54e-38 - - - S - - - Protein of unknown function (DUF1461)
LKPMBICO_01406 3.79e-118 dedA - - S ko:K03975 - ko00000 SNARE associated Golgi protein
LKPMBICO_01407 1.63e-118 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LKPMBICO_01408 2.55e-65 yugI - - J ko:K07570 - ko00000 general stress protein
LKPMBICO_01409 1.06e-39 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
LKPMBICO_01410 1.89e-113 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
LKPMBICO_01424 5.21e-226 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LKPMBICO_01425 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LKPMBICO_01426 6.58e-245 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LKPMBICO_01427 9.88e-244 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LKPMBICO_01428 1.04e-79 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LKPMBICO_01429 6.3e-104 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LKPMBICO_01430 5.08e-241 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
LKPMBICO_01431 1.15e-77 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
LKPMBICO_01432 9.31e-71 - 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 restriction endonuclease
LKPMBICO_01433 0.0 - - - L - - - Type III restriction enzyme, res subunit
LKPMBICO_01435 2e-47 - - - - - - - -
LKPMBICO_01436 2.66e-86 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LKPMBICO_01437 5.25e-79 - - - K - - - Transcriptional regulator, MarR family
LKPMBICO_01438 2.45e-128 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKPMBICO_01439 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LKPMBICO_01440 2.98e-131 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
LKPMBICO_01441 8.96e-125 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LKPMBICO_01442 1.42e-247 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKPMBICO_01443 1.16e-60 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LKPMBICO_01444 4.61e-84 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LKPMBICO_01445 1.45e-274 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
LKPMBICO_01446 3.3e-160 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LKPMBICO_01447 4.27e-130 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
LKPMBICO_01448 1.48e-139 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LKPMBICO_01449 1.55e-290 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LKPMBICO_01450 2.1e-305 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LKPMBICO_01451 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LKPMBICO_01452 1.05e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
LKPMBICO_01453 2.26e-59 ykuL - - S - - - CBS domain
LKPMBICO_01454 3.44e-92 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LKPMBICO_01455 4.06e-224 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LKPMBICO_01456 3.24e-115 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
LKPMBICO_01458 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LKPMBICO_01459 2.92e-28 yheA - - S - - - Belongs to the UPF0342 family
LKPMBICO_01460 6.56e-163 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
LKPMBICO_01461 1.22e-144 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LKPMBICO_01463 3.15e-69 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
LKPMBICO_01464 1.16e-121 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_01465 4.47e-87 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LKPMBICO_01466 3.39e-125 ytmP - - M - - - Choline/ethanolamine kinase
LKPMBICO_01467 8.2e-131 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LKPMBICO_01468 2.95e-59 ytpP - - CO - - - Thioredoxin
LKPMBICO_01469 1.49e-96 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKPMBICO_01470 1.07e-10 - - - - - - - -
LKPMBICO_01473 5.63e-20 - - - L - - - DnaD domain protein
LKPMBICO_01482 1.9e-55 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
LKPMBICO_01484 2.83e-10 - - - K - - - sequence-specific DNA binding
LKPMBICO_01485 2.17e-152 - - - L - - - Belongs to the 'phage' integrase family
LKPMBICO_01486 3.21e-296 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LKPMBICO_01487 1.44e-281 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LKPMBICO_01488 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
LKPMBICO_01489 5.74e-88 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
LKPMBICO_01490 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LKPMBICO_01491 8.5e-137 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LKPMBICO_01492 3.05e-62 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LKPMBICO_01493 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LKPMBICO_01494 1.56e-96 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
LKPMBICO_01495 5.69e-137 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LKPMBICO_01496 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LKPMBICO_01497 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LKPMBICO_01498 4.44e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LKPMBICO_01499 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LKPMBICO_01500 1.92e-90 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
LKPMBICO_01501 5.93e-229 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
LKPMBICO_01502 1.58e-39 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
LKPMBICO_01503 7.07e-99 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LKPMBICO_01504 4.64e-89 yqeK - - H - - - Hydrolase, HD family
LKPMBICO_01505 2.79e-65 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LKPMBICO_01506 3.23e-104 - - - H - - - Nodulation protein S (NodS)
LKPMBICO_01507 5.66e-154 ylbM - - S - - - Belongs to the UPF0348 family
LKPMBICO_01508 1.58e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
LKPMBICO_01509 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LKPMBICO_01510 3.48e-114 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
LKPMBICO_01511 4.86e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
LKPMBICO_01512 6.9e-37 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
LKPMBICO_01513 8.13e-171 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LKPMBICO_01514 7.31e-164 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LKPMBICO_01515 1.82e-49 - - - - - - - -
LKPMBICO_01516 1.9e-118 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
LKPMBICO_01517 5.41e-75 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LKPMBICO_01518 3.15e-200 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LKPMBICO_01519 3.59e-285 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LKPMBICO_01520 3.26e-140 - - - L ko:K07484 - ko00000 Transposase IS66 family
LKPMBICO_01521 4.25e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
LKPMBICO_01523 4.68e-137 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LKPMBICO_01525 1.46e-141 csrR - - K - - - response regulator
LKPMBICO_01526 2.34e-104 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKPMBICO_01527 8.2e-106 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKPMBICO_01528 2.4e-151 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKPMBICO_01529 1.6e-24 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LKPMBICO_01530 4.75e-170 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
LKPMBICO_01531 4.27e-143 - - - - - - - -
LKPMBICO_01532 1.61e-147 - - - - - - - -
LKPMBICO_01533 1.45e-48 - - - S - - - Protein conserved in bacteria
LKPMBICO_01534 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LKPMBICO_01535 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
LKPMBICO_01536 7.18e-47 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LKPMBICO_01537 3.85e-132 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LKPMBICO_01538 2.46e-183 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKPMBICO_01539 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKPMBICO_01540 4.39e-104 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LKPMBICO_01541 6.31e-154 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
LKPMBICO_01542 5.91e-65 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LKPMBICO_01543 1.17e-235 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LKPMBICO_01544 1.29e-106 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LKPMBICO_01545 7.41e-41 ynzC - - S - - - UPF0291 protein
LKPMBICO_01546 3.98e-36 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LKPMBICO_01547 2.28e-118 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LKPMBICO_01548 2.16e-58 - - - S - - - mazG nucleotide pyrophosphohydrolase
LKPMBICO_01549 6.19e-85 yciQ - - P - - - membrane protein (DUF2207)
LKPMBICO_01551 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LKPMBICO_01552 3.62e-49 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LKPMBICO_01553 9.08e-90 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
LKPMBICO_01554 1.74e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
LKPMBICO_01555 8.22e-203 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LKPMBICO_01556 1.69e-59 yqhL - - P - - - Rhodanese-like protein
LKPMBICO_01557 3.58e-23 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
LKPMBICO_01558 4.97e-140 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LKPMBICO_01559 1.56e-257 ynbB - - P - - - aluminum resistance
LKPMBICO_01560 1.3e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
LKPMBICO_01561 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LKPMBICO_01563 4.32e-47 - 2.1.1.63 - H ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKPMBICO_01564 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
LKPMBICO_01565 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LKPMBICO_01566 8.26e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LKPMBICO_01567 2.86e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LKPMBICO_01568 1.58e-131 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LKPMBICO_01569 2.52e-196 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LKPMBICO_01570 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LKPMBICO_01571 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKPMBICO_01572 1.16e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LKPMBICO_01573 1.25e-216 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LKPMBICO_01574 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
LKPMBICO_01575 4.38e-35 ylxQ - - J - - - ribosomal protein
LKPMBICO_01576 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LKPMBICO_01577 6.33e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LKPMBICO_01578 1.16e-151 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LKPMBICO_01579 7.4e-120 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LKPMBICO_01580 1.51e-165 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LKPMBICO_01581 3.65e-75 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LKPMBICO_01582 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LKPMBICO_01583 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LKPMBICO_01584 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LKPMBICO_01586 4.96e-257 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKPMBICO_01587 7.44e-153 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_01588 1.83e-41 - - - - - - - -
LKPMBICO_01589 2.05e-138 ampC - - V - - - Beta-lactamase
LKPMBICO_01590 3.8e-140 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
LKPMBICO_01591 2.09e-277 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
LKPMBICO_01592 1.19e-111 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LKPMBICO_01593 1.04e-230 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LKPMBICO_01594 2.15e-113 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LKPMBICO_01595 1.9e-171 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LKPMBICO_01596 2.18e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LKPMBICO_01597 2.33e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LKPMBICO_01598 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKPMBICO_01599 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LKPMBICO_01600 2.82e-74 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKPMBICO_01601 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LKPMBICO_01602 3.29e-181 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LKPMBICO_01603 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LKPMBICO_01604 6.22e-70 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LKPMBICO_01605 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
LKPMBICO_01606 1.71e-261 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LKPMBICO_01607 2.82e-214 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
LKPMBICO_01608 2.29e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LKPMBICO_01609 6.63e-21 - - - S - - - Protein of unknown function (DUF2969)
LKPMBICO_01610 2.21e-236 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LKPMBICO_01611 8.06e-36 - 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LKPMBICO_01612 5.39e-120 - - - M - - - Phosphotransferase enzyme family
LKPMBICO_01613 8.34e-132 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LKPMBICO_01614 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LKPMBICO_01615 7.57e-153 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LKPMBICO_01616 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LKPMBICO_01617 1.55e-177 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LKPMBICO_01618 8.79e-193 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LKPMBICO_01619 3.18e-115 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LKPMBICO_01620 3.99e-238 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LKPMBICO_01621 3.24e-144 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LKPMBICO_01622 9.24e-75 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LKPMBICO_01623 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LKPMBICO_01624 7.35e-69 yloU - - S - - - Asp23 family, cell envelope-related function
LKPMBICO_01625 2.99e-303 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
LKPMBICO_01626 3.32e-307 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LKPMBICO_01627 4.4e-180 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LKPMBICO_01628 9.72e-35 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LKPMBICO_01629 7.23e-130 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LKPMBICO_01630 1.04e-293 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LKPMBICO_01631 1.06e-185 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LKPMBICO_01632 6.15e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LKPMBICO_01633 9.04e-263 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LKPMBICO_01634 1.32e-55 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LKPMBICO_01635 1.99e-37 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LKPMBICO_01636 2.27e-74 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LKPMBICO_01637 6.45e-144 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LKPMBICO_01638 2.19e-78 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
LKPMBICO_01639 2.91e-249 - - - E ko:K03294 - ko00000 amino acid
LKPMBICO_01640 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LKPMBICO_01641 2e-257 - - - L - - - Belongs to the 'phage' integrase family
LKPMBICO_01644 2.83e-19 - - - S - - - Domain of unknown function (DUF4393)
LKPMBICO_01648 4.1e-48 - - - K - - - Peptidase S24-like
LKPMBICO_01649 5.65e-23 - - - - - - - -
LKPMBICO_01651 3.61e-20 - - - K - - - Cro/C1-type HTH DNA-binding domain
LKPMBICO_01654 2.48e-19 - - - K - - - Helix-turn-helix XRE-family like proteins
LKPMBICO_01655 2.67e-103 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
LKPMBICO_01662 1.14e-66 - - - S - - - Putative HNHc nuclease
LKPMBICO_01663 7.4e-32 - - - L - - - N-terminal phage replisome organiser (Phage_rep_org_N)
LKPMBICO_01666 1.06e-27 - - - - - - - -
LKPMBICO_01667 9.34e-72 - - - - - - - -
LKPMBICO_01679 1.18e-45 - - - S - - - Phage transcriptional regulator, ArpU family
LKPMBICO_01680 3.92e-70 - - - V - - - Abi-like protein
LKPMBICO_01683 4.73e-116 - - - L - - - HNH nucleases
LKPMBICO_01684 3.61e-102 - - - L - - - Phage terminase, small subunit
LKPMBICO_01685 0.0 - - - S - - - Phage Terminase
LKPMBICO_01687 1.16e-262 - - - S - - - Phage portal protein
LKPMBICO_01688 6e-154 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
LKPMBICO_01689 2.14e-279 - - - S - - - Phage capsid family
LKPMBICO_01690 3.09e-29 - - - S - - - Phage gp6-like head-tail connector protein
LKPMBICO_01691 8.03e-81 - - - S - - - Phage head-tail joining protein
LKPMBICO_01692 4.8e-86 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LKPMBICO_01693 2.08e-84 - - - S - - - Protein of unknown function (DUF806)
LKPMBICO_01694 6.32e-158 - - - S - - - Phage tail tube protein
LKPMBICO_01695 4.74e-75 - - - S - - - Phage tail assembly chaperone proteins, TAC
LKPMBICO_01699 4.86e-129 - - - M - - - by MetaGeneAnnotator
LKPMBICO_01701 0.0 - - - L - - - Phage tail tape measure protein TP901
LKPMBICO_01702 3.79e-101 - - - S - - - Phage tail protein
LKPMBICO_01703 1.08e-153 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
LKPMBICO_01705 8.68e-32 - - - S - - - Calcineurin-like phosphoesterase
LKPMBICO_01706 6.19e-06 - - - N - - - Bacterial Ig-like domain 2
LKPMBICO_01712 2.26e-14 - - - S - - - Bacteriophage holin family
LKPMBICO_01713 3.37e-145 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
LKPMBICO_01714 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LKPMBICO_01715 2.6e-53 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LKPMBICO_01716 7.62e-147 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LKPMBICO_01717 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKPMBICO_01718 0.000646 - - - S - - - Tetratricopeptide repeat
LKPMBICO_01719 9.71e-274 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LKPMBICO_01720 4.78e-246 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LKPMBICO_01721 3.67e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LKPMBICO_01722 3.87e-315 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LKPMBICO_01723 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKPMBICO_01724 1.72e-29 ykzG - - S - - - Belongs to the UPF0356 family
LKPMBICO_01725 3.51e-33 - - - - - - - -
LKPMBICO_01726 1.36e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKPMBICO_01727 2.58e-22 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
LKPMBICO_01728 3.42e-31 yktA - - S - - - Belongs to the UPF0223 family
LKPMBICO_01729 3.49e-95 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
LKPMBICO_01730 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LKPMBICO_01731 1.09e-187 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LKPMBICO_01732 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
LKPMBICO_01733 2.92e-189 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
LKPMBICO_01734 3.51e-125 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LKPMBICO_01735 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LKPMBICO_01736 2.86e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
LKPMBICO_01737 3.53e-94 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
LKPMBICO_01738 3.35e-65 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LKPMBICO_01739 5.17e-167 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LKPMBICO_01740 6.07e-123 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LKPMBICO_01741 1.85e-40 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKPMBICO_01742 4.77e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKPMBICO_01743 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKPMBICO_01744 4.32e-283 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LKPMBICO_01745 1.63e-173 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LKPMBICO_01746 6.95e-96 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LKPMBICO_01747 1.4e-291 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LKPMBICO_01748 2.89e-106 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LKPMBICO_01749 3.54e-73 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LKPMBICO_01750 7.08e-16 - - - S - - - Acyltransferase family
LKPMBICO_01751 1.19e-81 - - - S - - - Acyltransferase family
LKPMBICO_01752 1.38e-242 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKPMBICO_01753 2.58e-156 - - - K - - - LysR substrate binding domain
LKPMBICO_01755 6.94e-28 - - - - - - - -
LKPMBICO_01756 2.81e-74 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LKPMBICO_01757 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LKPMBICO_01758 3.64e-63 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
LKPMBICO_01759 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LKPMBICO_01760 2.2e-187 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LKPMBICO_01761 1.79e-134 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LKPMBICO_01762 3.07e-142 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LKPMBICO_01763 2.3e-172 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
LKPMBICO_01764 2.53e-156 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
LKPMBICO_01765 6.38e-120 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
LKPMBICO_01766 4.38e-271 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LKPMBICO_01767 1.35e-46 ypmB - - S - - - Protein conserved in bacteria
LKPMBICO_01768 3e-179 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LKPMBICO_01769 4.9e-300 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
LKPMBICO_01770 5.71e-72 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
LKPMBICO_01771 2.55e-107 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LKPMBICO_01772 7.32e-101 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LKPMBICO_01773 4.35e-160 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKPMBICO_01774 1.11e-114 - - - M - - - transferase activity, transferring glycosyl groups
LKPMBICO_01775 1.05e-107 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
LKPMBICO_01776 3.08e-126 - - - M - - - Glycosyltransferase like family 2
LKPMBICO_01779 3.43e-147 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LKPMBICO_01780 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LKPMBICO_01781 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
LKPMBICO_01783 5.44e-87 - - - L - - - Phage integrase, N-terminal SAM-like domain
LKPMBICO_01784 1.89e-142 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKPMBICO_01785 1.85e-136 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LKPMBICO_01786 1.45e-167 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LKPMBICO_01787 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
LKPMBICO_01788 1.36e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LKPMBICO_01789 7.52e-74 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LKPMBICO_01790 5.11e-171 - - - C - - - Aldo keto reductase
LKPMBICO_01791 5.19e-31 - - - K - - - regulatory protein
LKPMBICO_01792 1.02e-141 ydhF - - S - - - Aldo keto reductase
LKPMBICO_01794 2.14e-99 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
LKPMBICO_01795 7.98e-69 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
LKPMBICO_01796 5.08e-33 yozE - - S - - - Belongs to the UPF0346 family
LKPMBICO_01797 7.29e-170 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LKPMBICO_01798 3.91e-122 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKPMBICO_01799 1.96e-106 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
LKPMBICO_01800 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKPMBICO_01801 1.42e-264 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LKPMBICO_01802 9.4e-151 - - - L - - - Belongs to the 'phage' integrase family
LKPMBICO_01803 6.67e-257 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
LKPMBICO_01804 1.04e-191 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
LKPMBICO_01805 5.49e-37 cas6 - - S - - - CRISPR-associated endoribonuclease Cas6
LKPMBICO_01806 4.21e-255 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
LKPMBICO_01807 6.4e-43 - - - L ko:K19138 - ko00000,ko02048 Pfam:DUF310
LKPMBICO_01808 6.65e-89 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
LKPMBICO_01809 2.97e-82 - - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
LKPMBICO_01810 1.07e-86 csm5 - - L ko:K19140 - ko00000,ko02048 RAMP superfamily
LKPMBICO_01811 6.72e-111 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LKPMBICO_01812 2.56e-42 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LKPMBICO_01813 4.31e-83 - - - S - - - Psort location Cytoplasmic, score
LKPMBICO_01814 1.45e-129 pgm - - G - - - Phosphoglycerate mutase family
LKPMBICO_01815 2.54e-49 - - - S - - - repeat protein
LKPMBICO_01816 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LKPMBICO_01818 8.63e-20 - - - - - - - -
LKPMBICO_01821 5.71e-110 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKPMBICO_01822 1.95e-88 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LKPMBICO_01823 3.97e-56 yodB - - K - - - Transcriptional regulator, HxlR family
LKPMBICO_01824 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LKPMBICO_01825 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKPMBICO_01826 6.6e-163 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LKPMBICO_01827 4.31e-127 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LKPMBICO_01828 2e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LKPMBICO_01829 2.79e-17 - - - - - - - -
LKPMBICO_01830 1.01e-182 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
LKPMBICO_01831 5.19e-56 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
LKPMBICO_01832 3.09e-149 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
LKPMBICO_01833 2.49e-96 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LKPMBICO_01834 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LKPMBICO_01835 2.53e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LKPMBICO_01836 1.03e-71 yjcF - - J - - - HAD-hyrolase-like
LKPMBICO_01837 3.83e-56 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LKPMBICO_01838 1.19e-164 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LKPMBICO_01839 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LKPMBICO_01840 1.07e-256 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
LKPMBICO_01841 1.29e-141 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LKPMBICO_01842 1.82e-238 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LKPMBICO_01843 2.13e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LKPMBICO_01844 3.01e-114 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LKPMBICO_01845 3.17e-173 - - - K - - - Transcriptional regulator
LKPMBICO_01846 7.65e-185 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
LKPMBICO_01847 1.16e-147 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LKPMBICO_01848 4.06e-218 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LKPMBICO_01849 3.49e-111 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LKPMBICO_01851 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LKPMBICO_01852 4.65e-219 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LKPMBICO_01853 6.27e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
LKPMBICO_01854 2.06e-34 - - - S - - - Family of unknown function (DUF5322)
LKPMBICO_01855 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LKPMBICO_01856 2.15e-51 - - - - - - - -
LKPMBICO_01859 2.37e-184 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
LKPMBICO_01860 9.72e-98 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LKPMBICO_01861 5.44e-130 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LKPMBICO_01862 1.76e-232 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LKPMBICO_01863 1.27e-92 - - - L - - - DNA alkylation repair enzyme
LKPMBICO_01864 3.47e-174 - - - EG - - - EamA-like transporter family
LKPMBICO_01865 2.75e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
LKPMBICO_01866 2.21e-256 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LKPMBICO_01867 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LKPMBICO_01868 1.24e-173 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LKPMBICO_01869 6.32e-219 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LKPMBICO_01870 4.92e-165 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LKPMBICO_01871 4.91e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LKPMBICO_01873 5.12e-119 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LKPMBICO_01874 1.94e-202 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LKPMBICO_01875 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
LKPMBICO_01876 2.3e-255 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LKPMBICO_01877 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LKPMBICO_01878 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
LKPMBICO_01879 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LKPMBICO_01880 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LKPMBICO_01881 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LKPMBICO_01883 6.49e-53 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LKPMBICO_01884 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LKPMBICO_01885 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKPMBICO_01886 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKPMBICO_01887 2.19e-252 FbpA - - K - - - Fibronectin-binding protein
LKPMBICO_01888 2.07e-52 - - - K - - - Transcriptional regulator
LKPMBICO_01889 9.72e-147 - - - S - - - EDD domain protein, DegV family
LKPMBICO_01890 3.9e-91 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
LKPMBICO_01891 4.83e-53 - - - S - - - ASCH
LKPMBICO_01892 1.85e-236 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LKPMBICO_01893 1.89e-96 - - - S - - - Calcineurin-like phosphoesterase
LKPMBICO_01894 2.08e-121 - - - EG - - - EamA-like transporter family
LKPMBICO_01895 6.64e-105 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-type Na efflux pump, permease component
LKPMBICO_01896 1.71e-142 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
LKPMBICO_01897 2.83e-26 - - - K - - - Psort location Cytoplasmic, score
LKPMBICO_01899 2.02e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LKPMBICO_01900 9.58e-288 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LKPMBICO_01901 1.84e-219 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LKPMBICO_01902 2.35e-76 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphatase family
LKPMBICO_01903 2.34e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LKPMBICO_01904 4.73e-40 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKPMBICO_01905 1.94e-222 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
LKPMBICO_01906 2.17e-276 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKPMBICO_01908 5.47e-114 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LKPMBICO_01909 4.63e-199 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LKPMBICO_01910 8.41e-40 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LKPMBICO_01911 1.2e-88 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LKPMBICO_01912 5.08e-197 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
LKPMBICO_01913 8.49e-106 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
LKPMBICO_01914 2.52e-112 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LKPMBICO_01915 1.12e-15 - - - M - - - Lysin motif
LKPMBICO_01916 1.62e-156 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LKPMBICO_01917 1.06e-79 - - - S - - - Helix-turn-helix domain
LKPMBICO_01918 6.24e-277 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LKPMBICO_01919 3.42e-59 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
LKPMBICO_01920 1.59e-151 icaA - - M - - - Glycosyl transferase family group 2
LKPMBICO_01921 5.36e-51 - - - - - - - -
LKPMBICO_01922 3.15e-109 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LKPMBICO_01924 3.78e-237 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LKPMBICO_01925 3.6e-263 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LKPMBICO_01926 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LKPMBICO_01927 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LKPMBICO_01928 6.6e-136 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
LKPMBICO_01929 2.35e-86 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKPMBICO_01930 1.12e-75 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
LKPMBICO_01931 1.96e-89 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LKPMBICO_01932 6.63e-167 - - - L - - - Belongs to the 'phage' integrase family
LKPMBICO_01933 1.09e-106 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LKPMBICO_01934 9.72e-259 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LKPMBICO_01935 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
LKPMBICO_01937 1.61e-101 - - - F - - - Hydrolase, nudix family
LKPMBICO_01938 2.7e-73 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LKPMBICO_01939 1.64e-87 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LKPMBICO_01940 1.38e-92 - - - M - - - GNAT acetyltransferase
LKPMBICO_01942 4.2e-246 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
LKPMBICO_01943 2.27e-83 ypsA - - S - - - Belongs to the UPF0398 family
LKPMBICO_01944 2.16e-236 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LKPMBICO_01945 5.8e-99 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LKPMBICO_01946 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
LKPMBICO_01947 1.11e-143 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
LKPMBICO_01948 8.77e-159 yitL - - S ko:K00243 - ko00000 S1 domain
LKPMBICO_01949 6.67e-67 - - - S - - - Protein of unknown function (DUF441)
LKPMBICO_01950 8.84e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LKPMBICO_01951 3.27e-127 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LKPMBICO_01952 3.83e-79 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LKPMBICO_01953 2.77e-75 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LKPMBICO_01954 6.85e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKPMBICO_01955 2.48e-74 - - - - - - - -
LKPMBICO_01956 1.79e-11 - - - S - - - Protein of unknown function (DUF805)
LKPMBICO_01957 1.02e-07 - - - S - - - Protein of unknown function (DUF805)
LKPMBICO_01958 9.76e-11 - - - S - - - Membrane
LKPMBICO_01959 6.04e-275 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LKPMBICO_01960 4.03e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LKPMBICO_01961 2.09e-154 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
LKPMBICO_01962 1.9e-226 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
LKPMBICO_01963 9.65e-125 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LKPMBICO_01964 4.85e-90 - - - - - - - -
LKPMBICO_01966 2.43e-20 - - - - - - - -
LKPMBICO_01967 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LKPMBICO_01968 1.55e-37 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
LKPMBICO_01969 2.13e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LKPMBICO_01972 2.65e-71 - - - V - - - endonuclease activity
LKPMBICO_01977 4.34e-48 - - - S - - - Phage regulatory protein Rha (Phage_pRha)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)