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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
LEFHLAGG_00001	6.94e-59	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
LEFHLAGG_00002	3.89e-112	-	-	-	-	-	-	-	-
LEFHLAGG_00003	3.82e-166	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEFHLAGG_00004	9.72e-259	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
LEFHLAGG_00005	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
LEFHLAGG_00007	5.63e-102	-	-	-	F	-	-	-	Hydrolase, nudix family
LEFHLAGG_00008	1.34e-73	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
LEFHLAGG_00009	3.84e-86	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
LEFHLAGG_00010	4.07e-92	-	-	-	M	-	-	-	GNAT acetyltransferase
LEFHLAGG_00012	3.22e-243	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
LEFHLAGG_00013	3.94e-84	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
LEFHLAGG_00014	7.56e-237	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
LEFHLAGG_00015	5.8e-99	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEFHLAGG_00016	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
LEFHLAGG_00017	9.82e-143	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
LEFHLAGG_00018	2.63e-160	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
LEFHLAGG_00019	1.16e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
LEFHLAGG_00020	6.23e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LEFHLAGG_00021	1.33e-126	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
LEFHLAGG_00022	3.83e-79	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEFHLAGG_00023	2.77e-75	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEFHLAGG_00024	2.78e-48	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEFHLAGG_00025	6.04e-275	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEFHLAGG_00026	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEFHLAGG_00027	5.15e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
LEFHLAGG_00028	4.46e-225	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
LEFHLAGG_00029	2.38e-125	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
LEFHLAGG_00031	3.31e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
LEFHLAGG_00032	6.3e-37	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
LEFHLAGG_00033	5.02e-63	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
LEFHLAGG_00040	1.05e-82	-	-	-	H	-	-	-	Methyltransferase domain
LEFHLAGG_00041	3.48e-92	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
LEFHLAGG_00042	1.58e-51	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
LEFHLAGG_00044	2.98e-30	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
LEFHLAGG_00045	6.56e-34	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
LEFHLAGG_00047	3.76e-106	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
LEFHLAGG_00048	8.67e-36	-	-	-	S	-	-	-	CHY zinc finger
LEFHLAGG_00049	2.54e-53	ywnA	-	-	K	-	-	-	Transcriptional regulator
LEFHLAGG_00050	8.23e-105	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
LEFHLAGG_00052	1.35e-82	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEFHLAGG_00053	1.75e-225	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEFHLAGG_00054	6.21e-183	-	5.1.3.6	-	GM	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	RmlD substrate binding domain
LEFHLAGG_00055	3.05e-119	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
LEFHLAGG_00056	1.29e-144	-	-	-	S	-	-	-	Glycosyltransferase WbsX
LEFHLAGG_00057	1.25e-44	-	-	-	S	-	-	-	Glycosyltransferase WbsX
LEFHLAGG_00058	1.47e-86	-	-	-	S	-	-	-	Glycosyltransferase WbsX
LEFHLAGG_00060	4.48e-28	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
LEFHLAGG_00062	3.22e-71	-	-	-	M	-	-	-	Glycosyltransferase like family 2
LEFHLAGG_00063	3.85e-48	rfbF	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
LEFHLAGG_00064	6.52e-89	-	-	-	M	-	-	-	Glycosyltransferase Family 4
LEFHLAGG_00065	6.65e-90	-	-	-	M	-	-	-	glycosyl transferase group 1
LEFHLAGG_00066	2.05e-95	-	-	-	M	-	-	-	glycosyl transferase group 1
LEFHLAGG_00067	4.91e-49	-	-	GT4	M	ko:K13004	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase 4-like
LEFHLAGG_00068	2.17e-99	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEFHLAGG_00069	2.02e-52	-	-	-	S	ko:K13006,ko:K19429	-	ko00000,ko01000,ko01005	Bacterial transferase hexapeptide (six repeats)
LEFHLAGG_00070	2.07e-98	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
LEFHLAGG_00071	2.89e-208	epsN	-	-	M	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
LEFHLAGG_00072	1.19e-271	capD	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
LEFHLAGG_00073	9.97e-83	-	-	-	D	-	-	-	AAA domain
LEFHLAGG_00074	3.93e-60	-	-	-	M	-	-	-	Chain length determinant protein
LEFHLAGG_00075	3.33e-52	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
LEFHLAGG_00076	3.94e-224	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
LEFHLAGG_00077	3.31e-81	-	-	-	-	-	-	-	-
LEFHLAGG_00078	4.55e-105	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
LEFHLAGG_00079	3.53e-144	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
LEFHLAGG_00080	9.13e-77	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
LEFHLAGG_00081	8.06e-240	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEFHLAGG_00082	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
LEFHLAGG_00083	1.85e-265	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
LEFHLAGG_00085	5.92e-80	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
LEFHLAGG_00086	7.81e-69	-	-	-	S	-	-	-	Membrane
LEFHLAGG_00087	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
LEFHLAGG_00089	2.58e-77	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
LEFHLAGG_00090	2.92e-257	-	-	-	L	-	-	-	Helicase C-terminal domain protein
LEFHLAGG_00091	8.4e-66	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
LEFHLAGG_00092	5.4e-116	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
LEFHLAGG_00093	6.61e-36	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
LEFHLAGG_00094	4.61e-153	-	-	-	T	-	-	-	diguanylate cyclase activity
LEFHLAGG_00095	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
LEFHLAGG_00096	7.01e-255	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
LEFHLAGG_00097	3.28e-253	-	-	-	S	-	-	-	Protein conserved in bacteria
LEFHLAGG_00098	7.65e-237	-	-	-	-	-	-	-	-
LEFHLAGG_00099	3.04e-160	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LEFHLAGG_00100	1.13e-17	-	-	-	T	-	-	-	diguanylate cyclase
LEFHLAGG_00101	5.84e-182	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
LEFHLAGG_00102	6.22e-197	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
LEFHLAGG_00103	2.45e-134	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
LEFHLAGG_00104	4.59e-121	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
LEFHLAGG_00105	3.47e-276	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
LEFHLAGG_00106	1.34e-254	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LEFHLAGG_00107	6.14e-177	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
LEFHLAGG_00108	1.06e-243	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
LEFHLAGG_00109	5.27e-203	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
LEFHLAGG_00110	1.05e-44	-	-	-	M	-	-	-	LysM domain
LEFHLAGG_00111	1.38e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
LEFHLAGG_00112	1.8e-67	-	-	-	M	-	-	-	LysM domain protein
LEFHLAGG_00113	7.86e-116	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
LEFHLAGG_00114	2.84e-106	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
LEFHLAGG_00116	1.14e-90	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
LEFHLAGG_00117	4.52e-131	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEFHLAGG_00118	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEFHLAGG_00119	1.61e-91	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
LEFHLAGG_00120	5.69e-104	ylmH	-	-	S	-	-	-	S4 domain protein
LEFHLAGG_00121	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
LEFHLAGG_00122	8.14e-43	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEFHLAGG_00123	4.52e-229	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEFHLAGG_00124	6.07e-240	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEFHLAGG_00125	9.12e-76	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEFHLAGG_00126	8.63e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEFHLAGG_00127	5.98e-233	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEFHLAGG_00128	1.21e-170	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEFHLAGG_00129	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
LEFHLAGG_00130	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
LEFHLAGG_00131	4.28e-179	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEFHLAGG_00132	2.65e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
LEFHLAGG_00134	5.43e-196	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
LEFHLAGG_00135	4.54e-124	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
LEFHLAGG_00136	3.24e-138	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
LEFHLAGG_00137	8.17e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_00138	3.02e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
LEFHLAGG_00139	7.95e-163	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
LEFHLAGG_00140	9.25e-95	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LEFHLAGG_00141	9.34e-71	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
LEFHLAGG_00142	8.12e-122	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
LEFHLAGG_00143	2.35e-207	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
LEFHLAGG_00144	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
LEFHLAGG_00145	2.27e-102	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
LEFHLAGG_00146	8.51e-170	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
LEFHLAGG_00147	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEFHLAGG_00148	1.01e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEFHLAGG_00149	1.45e-204	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
LEFHLAGG_00150	2.45e-225	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEFHLAGG_00151	9e-73	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
LEFHLAGG_00152	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEFHLAGG_00153	6.66e-30	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
LEFHLAGG_00154	6.66e-247	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
LEFHLAGG_00156	6.35e-97	uspA	-	-	T	-	-	-	universal stress protein
LEFHLAGG_00157	1.31e-70	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
LEFHLAGG_00158	2.99e-252	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
LEFHLAGG_00159	2.95e-158	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
LEFHLAGG_00161	1.44e-94	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
LEFHLAGG_00162	3e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
LEFHLAGG_00163	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
LEFHLAGG_00164	0.0	-	-	-	S	-	-	-	membrane
LEFHLAGG_00165	4.3e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEFHLAGG_00166	5.81e-267	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
LEFHLAGG_00167	1.68e-128	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
LEFHLAGG_00168	2.14e-179	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEFHLAGG_00170	1.68e-22	-	-	-	-	-	-	-	-
LEFHLAGG_00171	1.79e-255	oatA	-	-	I	-	-	-	Acyltransferase
LEFHLAGG_00172	1.65e-272	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEFHLAGG_00173	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEFHLAGG_00174	1.07e-73	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEFHLAGG_00177	9.72e-51	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
LEFHLAGG_00178	2.54e-93	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEFHLAGG_00179	1.02e-78	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
LEFHLAGG_00180	5.23e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
LEFHLAGG_00181	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEFHLAGG_00182	3.86e-20	cvpA	-	-	S	-	-	-	Colicin V production protein
LEFHLAGG_00183	3.67e-17	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LEFHLAGG_00184	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
LEFHLAGG_00185	1.57e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEFHLAGG_00186	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
LEFHLAGG_00187	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEFHLAGG_00188	1.06e-236	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEFHLAGG_00189	1.25e-153	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
LEFHLAGG_00190	3.5e-18	-	-	-	-	-	-	-	-
LEFHLAGG_00191	3.91e-184	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEFHLAGG_00192	4.44e-85	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
LEFHLAGG_00193	4.95e-311	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
LEFHLAGG_00194	3.54e-150	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
LEFHLAGG_00195	2.92e-264	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
LEFHLAGG_00197	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
LEFHLAGG_00199	1.06e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
LEFHLAGG_00200	5.96e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEFHLAGG_00201	5.81e-231	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEFHLAGG_00202	1.45e-193	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEFHLAGG_00203	1.54e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEFHLAGG_00204	1.41e-287	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEFHLAGG_00205	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEFHLAGG_00206	1.25e-255	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
LEFHLAGG_00207	1.84e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEFHLAGG_00208	2.09e-111	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEFHLAGG_00209	7.25e-85	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
LEFHLAGG_00210	7.38e-116	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
LEFHLAGG_00211	1.63e-31	ymfH	-	-	S	-	-	-	Peptidase M16
LEFHLAGG_00212	1.54e-133	ymfH	-	-	S	-	-	-	Peptidase M16
LEFHLAGG_00213	2.1e-136	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
LEFHLAGG_00214	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
LEFHLAGG_00215	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEFHLAGG_00216	2.88e-124	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
LEFHLAGG_00217	2.89e-83	-	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
LEFHLAGG_00218	1.61e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEFHLAGG_00219	2.84e-249	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEFHLAGG_00220	8.5e-24	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
LEFHLAGG_00221	3.08e-163	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
LEFHLAGG_00222	1.59e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
LEFHLAGG_00223	1.1e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEFHLAGG_00224	4.54e-87	ybbR	-	-	S	-	-	-	YbbR-like protein
LEFHLAGG_00225	3.93e-162	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEFHLAGG_00226	4.8e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
LEFHLAGG_00227	4.26e-146	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
LEFHLAGG_00228	3.34e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
LEFHLAGG_00229	1e-72	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
LEFHLAGG_00230	7.01e-181	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
LEFHLAGG_00231	1.52e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEFHLAGG_00232	1.68e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
LEFHLAGG_00233	1.94e-53	-	-	-	-	-	-	-	-
LEFHLAGG_00234	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LEFHLAGG_00235	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEFHLAGG_00236	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
LEFHLAGG_00237	1.47e-222	eriC	-	-	P	ko:K03281	-	ko00000	chloride
LEFHLAGG_00238	1.33e-189	-	-	-	E	-	-	-	Major Facilitator Superfamily
LEFHLAGG_00239	2.3e-211	yclK	-	-	T	-	-	-	Histidine kinase
LEFHLAGG_00240	3.94e-134	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
LEFHLAGG_00241	2.02e-167	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEFHLAGG_00242	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEFHLAGG_00243	9.95e-165	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEFHLAGG_00244	1.99e-264	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
LEFHLAGG_00245	1.19e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEFHLAGG_00246	2.76e-175	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
LEFHLAGG_00248	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEFHLAGG_00249	2.05e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
LEFHLAGG_00250	9.11e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
LEFHLAGG_00251	5.03e-161	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
LEFHLAGG_00252	5.61e-102	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
LEFHLAGG_00253	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEFHLAGG_00254	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEFHLAGG_00255	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEFHLAGG_00256	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LEFHLAGG_00257	4.11e-143	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEFHLAGG_00258	4.12e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEFHLAGG_00259	2.17e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
LEFHLAGG_00260	1.02e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
LEFHLAGG_00261	8.32e-103	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFHLAGG_00262	7.27e-111	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
LEFHLAGG_00263	3.12e-79	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
LEFHLAGG_00264	6.18e-205	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEFHLAGG_00265	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEFHLAGG_00266	1.49e-121	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
LEFHLAGG_00267	7.08e-105	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEFHLAGG_00269	1.66e-110	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEFHLAGG_00270	1.72e-06	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEFHLAGG_00272	9.73e-47	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
LEFHLAGG_00274	1.12e-11	xre	-	-	K	-	-	-	sequence-specific DNA binding
LEFHLAGG_00281	3.65e-42	-	-	-	L	-	-	-	DNA replication protein
LEFHLAGG_00282	1.96e-164	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
LEFHLAGG_00284	5.27e-46	-	-	-	L	-	-	-	DNA replication protein
LEFHLAGG_00287	2.61e-67	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
LEFHLAGG_00288	3.04e-159	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
LEFHLAGG_00289	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
LEFHLAGG_00290	0.0	ydaO	-	-	E	-	-	-	amino acid
LEFHLAGG_00291	2.57e-264	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
LEFHLAGG_00292	5.76e-16	-	-	-	P	ko:K12952	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
LEFHLAGG_00293	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEFHLAGG_00294	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEFHLAGG_00295	1.14e-40	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEFHLAGG_00296	1.52e-126	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEFHLAGG_00297	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
LEFHLAGG_00298	2.51e-206	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEFHLAGG_00299	1.67e-08	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LEFHLAGG_00301	5.25e-88	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
LEFHLAGG_00302	2.82e-178	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
LEFHLAGG_00303	1.72e-104	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
LEFHLAGG_00304	9.92e-121	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEFHLAGG_00305	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
LEFHLAGG_00306	4.64e-105	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
LEFHLAGG_00307	2.18e-83	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEFHLAGG_00308	4.16e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
LEFHLAGG_00309	6.62e-126	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEFHLAGG_00310	3.8e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEFHLAGG_00311	5.45e-268	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEFHLAGG_00312	3.69e-79	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEFHLAGG_00313	2.25e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
LEFHLAGG_00314	2.75e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
LEFHLAGG_00315	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
LEFHLAGG_00316	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEFHLAGG_00317	7.73e-204	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEFHLAGG_00318	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEFHLAGG_00319	1.04e-70	-	-	-	-	-	-	-	-
LEFHLAGG_00320	2.18e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEFHLAGG_00321	2.21e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEFHLAGG_00322	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEFHLAGG_00323	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEFHLAGG_00324	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
LEFHLAGG_00325	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEFHLAGG_00326	3.3e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
LEFHLAGG_00327	1.93e-92	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
LEFHLAGG_00328	1.88e-138	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEFHLAGG_00329	3.45e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEFHLAGG_00330	2.26e-263	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
LEFHLAGG_00331	1.49e-312	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEFHLAGG_00332	1.38e-195	yacL	-	-	S	-	-	-	domain protein
LEFHLAGG_00333	1.14e-283	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEFHLAGG_00334	1.68e-95	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
LEFHLAGG_00335	3.35e-25	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
LEFHLAGG_00336	7.36e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
LEFHLAGG_00337	2.56e-45	-	-	-	S	-	-	-	Enterocin A Immunity
LEFHLAGG_00338	4.1e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEFHLAGG_00339	2.13e-163	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
LEFHLAGG_00340	2.66e-148	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEFHLAGG_00342	7.99e-55	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
LEFHLAGG_00343	5.71e-317	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
LEFHLAGG_00344	2.65e-165	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEFHLAGG_00345	3.1e-307	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEFHLAGG_00346	3.32e-113	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LEFHLAGG_00347	7.59e-123	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
LEFHLAGG_00348	2.13e-115	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEFHLAGG_00351	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
LEFHLAGG_00352	8.07e-120	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
LEFHLAGG_00353	2.34e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
LEFHLAGG_00354	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
LEFHLAGG_00355	3.03e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
LEFHLAGG_00356	2.04e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
LEFHLAGG_00357	6.57e-68	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
LEFHLAGG_00358	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
LEFHLAGG_00359	9.8e-152	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
LEFHLAGG_00360	3.74e-154	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
LEFHLAGG_00361	2.8e-89	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
LEFHLAGG_00362	5.77e-215	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LEFHLAGG_00363	8.6e-230	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
LEFHLAGG_00364	0.0	-	-	-	E	-	-	-	Amino acid permease
LEFHLAGG_00365	2.59e-109	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
LEFHLAGG_00366	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
LEFHLAGG_00367	1.92e-95	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
LEFHLAGG_00368	3.51e-270	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
LEFHLAGG_00369	1.64e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
LEFHLAGG_00370	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
LEFHLAGG_00373	9.82e-202	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
LEFHLAGG_00374	7.62e-161	mocA	-	-	S	-	-	-	Oxidoreductase
LEFHLAGG_00375	7.99e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
LEFHLAGG_00376	1.99e-214	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
LEFHLAGG_00377	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LEFHLAGG_00378	1.22e-241	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
LEFHLAGG_00379	5.53e-157	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
LEFHLAGG_00380	8.3e-210	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LEFHLAGG_00381	2.25e-57	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LEFHLAGG_00382	2.45e-252	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LEFHLAGG_00383	3.93e-270	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
LEFHLAGG_00384	1.75e-09	-	-	-	O	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
LEFHLAGG_00385	1.02e-277	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
LEFHLAGG_00386	1.13e-262	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
LEFHLAGG_00387	7.11e-33	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
LEFHLAGG_00388	7.98e-54	-	-	-	-	-	-	-	-
LEFHLAGG_00390	1.27e-228	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
LEFHLAGG_00391	1.3e-118	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
LEFHLAGG_00392	1.79e-148	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEFHLAGG_00393	5.56e-124	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
LEFHLAGG_00394	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
LEFHLAGG_00395	4.56e-48	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
LEFHLAGG_00396	7.75e-255	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
LEFHLAGG_00397	2.39e-53	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEFHLAGG_00398	3.26e-17	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEFHLAGG_00399	2.58e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
LEFHLAGG_00400	5.7e-82	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
LEFHLAGG_00401	4.34e-162	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
LEFHLAGG_00402	1.61e-311	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
LEFHLAGG_00403	7.97e-90	mleR	-	-	K	-	-	-	LysR family
LEFHLAGG_00404	3.65e-74	napB	-	-	K	-	-	-	transcriptional
LEFHLAGG_00405	4.74e-52	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEFHLAGG_00406	2.3e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
LEFHLAGG_00407	2.15e-59	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
LEFHLAGG_00408	3.36e-16	fhaB	-	-	M	ko:K15125,ko:K18491	ko04550,ko05133,map04550,map05133	ko00000,ko00001,ko00536,ko03000	translation initiation factor activity
LEFHLAGG_00409	6.55e-142	-	-	-	M	-	-	-	Rib/alpha-like repeat
LEFHLAGG_00411	5.96e-130	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
LEFHLAGG_00412	2.72e-78	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
LEFHLAGG_00413	2.14e-53	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LEFHLAGG_00414	3.46e-39	-	-	-	S	-	-	-	Belongs to the HesB IscA family
LEFHLAGG_00415	1.7e-84	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
LEFHLAGG_00417	5e-67	-	-	-	K	-	-	-	LysR substrate binding domain
LEFHLAGG_00418	9.56e-152	-	-	-	S	-	-	-	Conserved hypothetical protein 698
LEFHLAGG_00419	1.19e-252	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
LEFHLAGG_00420	3.1e-137	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEFHLAGG_00421	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEFHLAGG_00422	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
LEFHLAGG_00423	1.1e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEFHLAGG_00424	1.81e-201	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEFHLAGG_00425	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
LEFHLAGG_00426	6.86e-193	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEFHLAGG_00427	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEFHLAGG_00428	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEFHLAGG_00429	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
LEFHLAGG_00430	6.48e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEFHLAGG_00431	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEFHLAGG_00432	4.29e-140	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
LEFHLAGG_00433	9.4e-148	-	-	-	S	-	-	-	Glycosyl transferase family 2
LEFHLAGG_00434	3.2e-81	-	-	-	D	-	-	-	peptidase
LEFHLAGG_00435	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
LEFHLAGG_00436	5.27e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
LEFHLAGG_00437	5.27e-53	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LEFHLAGG_00438	3.25e-307	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
LEFHLAGG_00439	5.01e-22	yneR	-	-	-	-	-	-	-
LEFHLAGG_00440	1.45e-289	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEFHLAGG_00441	1.25e-282	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
LEFHLAGG_00442	2.23e-126	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
LEFHLAGG_00443	1.29e-192	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
LEFHLAGG_00444	1.25e-06	-	-	-	K	-	-	-	YsiA-like protein, C-terminal region
LEFHLAGG_00445	6.3e-141	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
LEFHLAGG_00446	1.31e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
LEFHLAGG_00447	4.41e-90	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
LEFHLAGG_00448	2.33e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
LEFHLAGG_00449	4.54e-278	pepF	-	-	E	-	-	-	Oligopeptidase F
LEFHLAGG_00450	6.14e-139	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
LEFHLAGG_00451	6.69e-223	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
LEFHLAGG_00452	1.88e-174	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
LEFHLAGG_00453	1.45e-80	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
LEFHLAGG_00454	3.06e-32	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
LEFHLAGG_00455	8.88e-42	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
LEFHLAGG_00456	6.45e-218	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
LEFHLAGG_00457	2.33e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
LEFHLAGG_00458	3.56e-268	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_00459	8.27e-301	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
LEFHLAGG_00460	2.02e-135	yxeH	-	-	S	-	-	-	hydrolase
LEFHLAGG_00461	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
LEFHLAGG_00462	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFHLAGG_00463	1.07e-125	yycH	-	-	S	-	-	-	YycH protein
LEFHLAGG_00464	2.73e-99	yycI	-	-	S	-	-	-	YycH protein
LEFHLAGG_00465	6.27e-20	-	-	-	S	-	-	-	YjbR
LEFHLAGG_00466	1.46e-147	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
LEFHLAGG_00467	2.33e-187	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
LEFHLAGG_00468	1.36e-94	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEFHLAGG_00469	8.46e-69	-	-	-	GM	-	-	-	NAD(P)H-binding
LEFHLAGG_00470	5.2e-34	-	-	-	K	-	-	-	MarR family transcriptional regulator
LEFHLAGG_00471	1.1e-111	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFHLAGG_00472	5.1e-61	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
LEFHLAGG_00473	1.6e-261	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
LEFHLAGG_00474	1.16e-172	-	-	-	S	-	-	-	interspecies interaction between organisms
LEFHLAGG_00479	1.32e-07	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
LEFHLAGG_00480	9.16e-34	arbx	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
LEFHLAGG_00481	1.4e-187	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
LEFHLAGG_00482	1.02e-185	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
LEFHLAGG_00483	2.07e-106	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEFHLAGG_00484	2.14e-141	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
LEFHLAGG_00485	7.58e-252	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
LEFHLAGG_00486	2.65e-35	-	-	-	-	-	-	-	-
LEFHLAGG_00487	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
LEFHLAGG_00488	1.01e-77	-	-	-	T	-	-	-	Universal stress protein family
LEFHLAGG_00490	3.82e-272	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEFHLAGG_00491	3.5e-214	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
LEFHLAGG_00492	8.87e-203	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEFHLAGG_00493	2.04e-35	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
LEFHLAGG_00494	3.63e-267	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
LEFHLAGG_00495	9.7e-250	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
LEFHLAGG_00496	4.35e-301	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEFHLAGG_00497	4.82e-20	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
LEFHLAGG_00498	9.08e-225	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
LEFHLAGG_00499	3.47e-75	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEFHLAGG_00500	3.66e-123	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEFHLAGG_00501	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
LEFHLAGG_00502	1.25e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
LEFHLAGG_00503	7.76e-20	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
LEFHLAGG_00508	1.25e-32	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
LEFHLAGG_00509	8.49e-14	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
LEFHLAGG_00510	3.98e-66	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
LEFHLAGG_00511	1.74e-206	spoVK	-	-	O	-	-	-	stage V sporulation protein K
LEFHLAGG_00512	8.5e-97	-	-	-	-	-	-	-	-
LEFHLAGG_00513	3.22e-119	-	-	-	-	-	-	-	-
LEFHLAGG_00514	1.38e-128	-	-	-	S	-	-	-	Domain of unknown function (DUF4343)
LEFHLAGG_00515	0.0	-	-	-	L	-	-	-	helicase activity
LEFHLAGG_00516	1.48e-233	-	-	-	K	-	-	-	DNA binding
LEFHLAGG_00517	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
LEFHLAGG_00518	1.56e-294	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
LEFHLAGG_00519	3.61e-296	-	-	-	S	-	-	-	Protein of unknown function DUF262
LEFHLAGG_00520	2.72e-268	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEFHLAGG_00521	5.09e-183	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
LEFHLAGG_00522	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEFHLAGG_00523	7.24e-295	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEFHLAGG_00524	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEFHLAGG_00525	2.29e-203	camS	-	-	S	-	-	-	sex pheromone
LEFHLAGG_00526	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEFHLAGG_00527	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
LEFHLAGG_00528	1.64e-182	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LEFHLAGG_00531	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
LEFHLAGG_00532	9.77e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEFHLAGG_00533	2.65e-166	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEFHLAGG_00534	4.33e-145	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEFHLAGG_00535	2.75e-28	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
LEFHLAGG_00536	6.27e-47	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
LEFHLAGG_00541	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEFHLAGG_00542	2.49e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
LEFHLAGG_00543	1.14e-118	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEFHLAGG_00544	1.23e-62	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
LEFHLAGG_00545	2e-26	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
LEFHLAGG_00546	1.1e-42	yabO	-	-	J	-	-	-	S4 domain protein
LEFHLAGG_00547	3.77e-172	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
LEFHLAGG_00548	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEFHLAGG_00549	1.45e-95	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEFHLAGG_00550	8.16e-202	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
LEFHLAGG_00551	2.07e-29	-	-	-	V	ko:K07448,ko:K07449	-	ko00000,ko02048	Restriction endonuclease
LEFHLAGG_00553	1.09e-110	-	-	-	S	-	-	-	(CBS) domain
LEFHLAGG_00554	4.44e-180	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEFHLAGG_00555	4.09e-261	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEFHLAGG_00556	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
LEFHLAGG_00557	8.18e-73	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
LEFHLAGG_00558	1.27e-131	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
LEFHLAGG_00559	6.72e-141	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LEFHLAGG_00560	2.6e-62	-	-	-	M	-	-	-	LysM domain protein
LEFHLAGG_00561	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
LEFHLAGG_00562	2.61e-110	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LEFHLAGG_00563	2.1e-41	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
LEFHLAGG_00564	7.57e-138	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
LEFHLAGG_00565	8.99e-111	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_00566	1.26e-86	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
LEFHLAGG_00567	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
LEFHLAGG_00568	9.33e-306	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
LEFHLAGG_00570	1.09e-77	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
LEFHLAGG_00571	1.04e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEFHLAGG_00572	3.6e-159	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEFHLAGG_00573	2.18e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEFHLAGG_00574	8.76e-140	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEFHLAGG_00575	2.27e-127	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEFHLAGG_00576	4.47e-71	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
LEFHLAGG_00577	1.93e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEFHLAGG_00578	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEFHLAGG_00579	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEFHLAGG_00580	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
LEFHLAGG_00581	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEFHLAGG_00582	8.94e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEFHLAGG_00583	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEFHLAGG_00584	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
LEFHLAGG_00585	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
LEFHLAGG_00586	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEFHLAGG_00587	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEFHLAGG_00588	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEFHLAGG_00589	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEFHLAGG_00590	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEFHLAGG_00591	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEFHLAGG_00592	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEFHLAGG_00593	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEFHLAGG_00594	2.93e-51	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEFHLAGG_00595	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
LEFHLAGG_00596	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEFHLAGG_00597	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEFHLAGG_00598	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEFHLAGG_00599	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEFHLAGG_00600	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEFHLAGG_00601	1.34e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEFHLAGG_00602	3.79e-129	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
LEFHLAGG_00603	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEFHLAGG_00604	3.24e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
LEFHLAGG_00605	9.93e-217	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEFHLAGG_00606	4.32e-100	-	-	-	K	-	-	-	rpiR family
LEFHLAGG_00607	1.63e-68	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
LEFHLAGG_00608	8.32e-188	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
LEFHLAGG_00609	2.79e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
LEFHLAGG_00610	2.87e-240	steT	-	-	E	ko:K03294	-	ko00000	amino acid
LEFHLAGG_00611	1.88e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
LEFHLAGG_00612	6.94e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
LEFHLAGG_00613	5.62e-125	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEFHLAGG_00614	2.45e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_00615	3.89e-17	-	-	-	-	-	-	-	-
LEFHLAGG_00616	1.28e-122	-	-	-	-	-	-	-	-
LEFHLAGG_00617	2.03e-16	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
LEFHLAGG_00618	1e-68	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
LEFHLAGG_00619	6.14e-269	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
LEFHLAGG_00620	5.89e-316	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEFHLAGG_00621	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
LEFHLAGG_00622	3.55e-101	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
LEFHLAGG_00623	6.84e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
LEFHLAGG_00624	5.54e-33	-	-	-	-	-	-	-	-
LEFHLAGG_00625	2.59e-101	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
LEFHLAGG_00626	7.93e-163	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
LEFHLAGG_00627	2.78e-126	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
LEFHLAGG_00628	8e-92	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEFHLAGG_00629	6.88e-200	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
LEFHLAGG_00630	2.8e-174	-	-	-	V	-	-	-	MatE
LEFHLAGG_00631	1.32e-57	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEFHLAGG_00632	5.52e-111	-	-	-	S	-	-	-	Alpha beta hydrolase
LEFHLAGG_00633	2.14e-121	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEFHLAGG_00634	2.12e-218	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEFHLAGG_00635	1.24e-137	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
LEFHLAGG_00636	1.49e-129	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
LEFHLAGG_00637	8.54e-45	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
LEFHLAGG_00638	1.09e-68	ccl	-	-	S	-	-	-	QueT transporter
LEFHLAGG_00640	2.66e-83	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
LEFHLAGG_00641	4.13e-29	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEFHLAGG_00642	1.44e-26	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEFHLAGG_00643	7.52e-44	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
LEFHLAGG_00644	1.81e-59	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
LEFHLAGG_00645	2.05e-30	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
LEFHLAGG_00646	3.06e-157	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
LEFHLAGG_00647	1.19e-65	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
LEFHLAGG_00648	1.11e-102	-	-	-	S	-	-	-	Putative threonine/serine exporter
LEFHLAGG_00649	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
LEFHLAGG_00650	1.77e-115	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
LEFHLAGG_00651	3.07e-119	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
LEFHLAGG_00652	4.51e-28	-	-	-	-	-	-	-	-
LEFHLAGG_00653	1.3e-74	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
LEFHLAGG_00654	4.48e-24	-	-	-	-	-	-	-	-
LEFHLAGG_00655	6.04e-82	-	-	-	I	-	-	-	alpha/beta hydrolase fold
LEFHLAGG_00656	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
LEFHLAGG_00657	3.58e-132	-	-	-	E	-	-	-	AzlC protein
LEFHLAGG_00658	2.11e-23	-	-	-	-	-	-	-	-
LEFHLAGG_00659	8.83e-164	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
LEFHLAGG_00660	5.52e-151	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
LEFHLAGG_00661	0.000274	-	-	-	S	-	-	-	zinc-ribbon domain
LEFHLAGG_00665	3.85e-08	-	-	-	S	-	-	-	Mor transcription activator family
LEFHLAGG_00666	1.44e-74	-	-	-	K	-	-	-	WYL domain
LEFHLAGG_00667	8.68e-159	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEFHLAGG_00668	5.45e-218	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
LEFHLAGG_00669	1.06e-146	ydbI	-	-	K	-	-	-	AI-2E family transporter
LEFHLAGG_00670	1.18e-75	-	-	-	EG	-	-	-	EamA-like transporter family
LEFHLAGG_00671	6.46e-98	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
LEFHLAGG_00672	3.96e-147	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
LEFHLAGG_00673	1.56e-86	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
LEFHLAGG_00674	2.21e-208	-	-	-	C	-	-	-	Luciferase-like monooxygenase
LEFHLAGG_00675	1.7e-55	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
LEFHLAGG_00676	1.57e-217	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
LEFHLAGG_00677	2.97e-132	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
LEFHLAGG_00678	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
LEFHLAGG_00679	8.43e-107	pncA	-	-	Q	-	-	-	isochorismatase
LEFHLAGG_00680	2.66e-80	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
LEFHLAGG_00681	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFHLAGG_00682	2.39e-108	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
LEFHLAGG_00683	1.5e-315	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
LEFHLAGG_00684	4.8e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
LEFHLAGG_00686	1.4e-224	XK27_08315	-	-	M	-	-	-	Sulfatase
LEFHLAGG_00687	4.85e-74	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
LEFHLAGG_00688	3.41e-33	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
LEFHLAGG_00689	9.34e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEFHLAGG_00690	7.25e-214	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
LEFHLAGG_00691	3.47e-160	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LEFHLAGG_00692	1.47e-223	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
LEFHLAGG_00693	4.58e-93	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEFHLAGG_00694	5.57e-77	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
LEFHLAGG_00695	8.41e-110	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
LEFHLAGG_00696	6.73e-72	-	-	-	-	-	-	-	-
LEFHLAGG_00697	2.66e-88	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
LEFHLAGG_00698	8.98e-192	XK27_08315	-	-	M	-	-	-	Sulfatase
LEFHLAGG_00699	2.72e-147	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
LEFHLAGG_00700	4.55e-20	-	-	-	-	-	-	-	-
LEFHLAGG_00701	9.88e-59	cps3I	-	-	G	-	-	-	Acyltransferase family
LEFHLAGG_00702	5.23e-186	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
LEFHLAGG_00703	1.61e-61	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
LEFHLAGG_00704	2.93e-196	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
LEFHLAGG_00705	5.01e-85	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
LEFHLAGG_00706	6.56e-120	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
LEFHLAGG_00707	7.97e-206	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEFHLAGG_00708	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LEFHLAGG_00709	2.28e-95	-	-	-	G	-	-	-	Peptidase_C39 like family
LEFHLAGG_00710	3.09e-43	-	-	-	-	-	-	-	-
LEFHLAGG_00712	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
LEFHLAGG_00713	2.25e-170	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
LEFHLAGG_00714	9.44e-55	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
LEFHLAGG_00715	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_00716	4.04e-240	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
LEFHLAGG_00717	1.47e-267	potE	-	-	E	-	-	-	Amino Acid
LEFHLAGG_00718	1.24e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
LEFHLAGG_00719	4.64e-170	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
LEFHLAGG_00721	8.31e-90	-	-	-	D	-	-	-	Peptidase family M23
LEFHLAGG_00722	6.7e-234	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
LEFHLAGG_00723	2.01e-247	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
LEFHLAGG_00724	8.19e-152	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
LEFHLAGG_00725	1.69e-115	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
LEFHLAGG_00726	1.15e-162	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
LEFHLAGG_00727	6.98e-141	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
LEFHLAGG_00728	1.28e-116	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
LEFHLAGG_00729	1.78e-91	epsB	-	-	M	-	-	-	biosynthesis protein
LEFHLAGG_00730	1.61e-26	-	-	-	S	-	-	-	EpsG family
LEFHLAGG_00731	2.45e-134	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
LEFHLAGG_00732	1.73e-133	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEFHLAGG_00734	2.93e-39	ftsK	-	-	I	ko:K03466	-	ko00000,ko03036	transferase activity, transferring acyl groups other than amino-acyl groups
LEFHLAGG_00735	8.88e-128	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
LEFHLAGG_00736	1.88e-123	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
LEFHLAGG_00737	4.23e-55	-	-	-	M	-	-	-	Glycosyl transferase family 8
LEFHLAGG_00739	2.07e-109	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
LEFHLAGG_00741	1.24e-147	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
LEFHLAGG_00743	9.07e-163	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEFHLAGG_00744	9.13e-239	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEFHLAGG_00745	2.26e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LEFHLAGG_00746	2.17e-159	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEFHLAGG_00747	1.29e-76	-	-	-	S	-	-	-	Glycosyltransferase like family 2
LEFHLAGG_00748	2.84e-148	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
LEFHLAGG_00749	3.04e-21	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEFHLAGG_00750	1.51e-113	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
LEFHLAGG_00751	7.28e-82	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
LEFHLAGG_00752	2.58e-191	-	-	-	EGP	-	-	-	Major Facilitator
LEFHLAGG_00754	9.43e-89	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
LEFHLAGG_00755	3.23e-36	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
LEFHLAGG_00756	2.19e-113	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
LEFHLAGG_00757	4.05e-129	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
LEFHLAGG_00758	3.99e-71	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
LEFHLAGG_00759	1.41e-137	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
LEFHLAGG_00760	3.22e-126	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
LEFHLAGG_00761	2.96e-131	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
LEFHLAGG_00762	5.51e-50	-	-	-	-	-	-	-	-
LEFHLAGG_00763	1.28e-72	-	-	-	I	-	-	-	Alpha/beta hydrolase family
LEFHLAGG_00764	3.04e-115	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
LEFHLAGG_00765	3.13e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
LEFHLAGG_00766	2.94e-242	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEFHLAGG_00767	3.11e-33	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
LEFHLAGG_00768	4.14e-138	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
LEFHLAGG_00769	4.97e-153	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
LEFHLAGG_00770	1.24e-103	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
LEFHLAGG_00771	1.04e-129	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
LEFHLAGG_00772	4.74e-161	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
LEFHLAGG_00773	2.3e-90	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
LEFHLAGG_00774	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
LEFHLAGG_00775	1.94e-78	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
LEFHLAGG_00776	4.96e-93	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
LEFHLAGG_00778	1.26e-83	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
LEFHLAGG_00779	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
LEFHLAGG_00780	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LEFHLAGG_00781	1.43e-44	-	-	-	-	-	-	-	-
LEFHLAGG_00782	3.93e-180	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEFHLAGG_00783	1.42e-197	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEFHLAGG_00784	1.57e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEFHLAGG_00785	2.33e-198	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
LEFHLAGG_00786	4.21e-53	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
LEFHLAGG_00788	1.09e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_00789	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
LEFHLAGG_00790	2.44e-235	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
LEFHLAGG_00791	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEFHLAGG_00792	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
LEFHLAGG_00793	6.11e-136	-	-	-	P	-	-	-	Integral membrane protein TerC family
LEFHLAGG_00794	1.86e-49	-	-	-	K	-	-	-	Transcriptional regulator
LEFHLAGG_00795	3.36e-122	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
LEFHLAGG_00796	7.11e-129	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_00797	1.12e-133	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEFHLAGG_00799	4.5e-23	-	-	-	V	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
LEFHLAGG_00800	1.44e-236	noxE	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEFHLAGG_00801	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEFHLAGG_00802	4.71e-259	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
LEFHLAGG_00803	5.7e-220	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
LEFHLAGG_00804	3.08e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
LEFHLAGG_00805	1.7e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
LEFHLAGG_00806	9.87e-89	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
LEFHLAGG_00807	8.78e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
LEFHLAGG_00808	7.3e-145	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
LEFHLAGG_00809	2.02e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEFHLAGG_00810	1.67e-263	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
LEFHLAGG_00812	5.69e-142	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
LEFHLAGG_00813	1.48e-95	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
LEFHLAGG_00814	1.54e-238	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
LEFHLAGG_00815	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
LEFHLAGG_00816	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
LEFHLAGG_00817	7.04e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
LEFHLAGG_00818	3.96e-76	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
LEFHLAGG_00819	1.71e-97	azlC	-	-	E	-	-	-	branched-chain amino acid
LEFHLAGG_00820	1.46e-42	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
LEFHLAGG_00821	2.21e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFHLAGG_00822	1.8e-69	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
LEFHLAGG_00823	2.01e-159	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEFHLAGG_00824	1.79e-10	ansR	-	-	K	-	-	-	Transcriptional regulator
LEFHLAGG_00826	2.34e-16	xre	-	-	K	-	-	-	sequence-specific DNA binding
LEFHLAGG_00832	3.17e-44	-	-	-	L	-	-	-	DNA replication protein
LEFHLAGG_00833	3.21e-68	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
LEFHLAGG_00834	8.75e-60	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
LEFHLAGG_00835	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
LEFHLAGG_00836	1.84e-138	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
LEFHLAGG_00838	8.87e-88	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
LEFHLAGG_00839	5.56e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
LEFHLAGG_00840	1.3e-52	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
LEFHLAGG_00842	2.99e-45	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
LEFHLAGG_00843	4.91e-317	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
LEFHLAGG_00844	3.19e-114	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_00848	1.16e-93	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEFHLAGG_00849	8.16e-155	ytbE	-	-	S	-	-	-	reductase
LEFHLAGG_00850	1.22e-57	ytcD	-	-	K	-	-	-	HxlR-like helix-turn-helix
LEFHLAGG_00851	8.41e-129	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
LEFHLAGG_00852	3.37e-86	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
LEFHLAGG_00853	4.26e-208	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
LEFHLAGG_00854	2.77e-69	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEFHLAGG_00855	1.03e-59	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
LEFHLAGG_00856	4.63e-30	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
LEFHLAGG_00857	2.6e-191	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
LEFHLAGG_00859	2.87e-52	-	-	-	K	-	-	-	LytTr DNA-binding domain
LEFHLAGG_00860	4.6e-145	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
LEFHLAGG_00861	1.36e-264	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
LEFHLAGG_00862	1.85e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
LEFHLAGG_00863	6.96e-197	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEFHLAGG_00864	2.46e-229	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEFHLAGG_00865	7.43e-217	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEFHLAGG_00866	1.97e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEFHLAGG_00867	1.25e-253	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
LEFHLAGG_00868	7.19e-276	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
LEFHLAGG_00869	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEFHLAGG_00870	7.69e-73	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
LEFHLAGG_00871	4.49e-78	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
LEFHLAGG_00872	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
LEFHLAGG_00873	7.19e-27	-	-	-	S	-	-	-	Cupredoxin-like domain
LEFHLAGG_00874	5.2e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
LEFHLAGG_00875	5.03e-190	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
LEFHLAGG_00876	1.16e-171	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
LEFHLAGG_00877	1.92e-101	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
LEFHLAGG_00878	2.4e-177	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
LEFHLAGG_00879	1.89e-217	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
LEFHLAGG_00880	1.23e-22	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
LEFHLAGG_00881	1.26e-149	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
LEFHLAGG_00882	2.57e-34	-	-	-	C	-	-	-	FMN_bind
LEFHLAGG_00884	1.04e-202	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
LEFHLAGG_00885	4.19e-249	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
LEFHLAGG_00886	1.14e-92	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
LEFHLAGG_00887	4.94e-164	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
LEFHLAGG_00888	3.26e-125	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
LEFHLAGG_00889	6.31e-104	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
LEFHLAGG_00890	2.02e-12	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
LEFHLAGG_00891	6.98e-78	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
LEFHLAGG_00892	1.22e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEFHLAGG_00894	6.78e-290	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEFHLAGG_00895	3.97e-81	-	-	-	C	-	-	-	FMN binding
LEFHLAGG_00896	1.24e-260	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
LEFHLAGG_00897	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
LEFHLAGG_00898	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
LEFHLAGG_00912	1.88e-185	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
LEFHLAGG_00913	1.57e-270	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
LEFHLAGG_00914	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFHLAGG_00915	1.37e-229	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
LEFHLAGG_00916	1.2e-144	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
LEFHLAGG_00917	1.53e-74	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
LEFHLAGG_00918	7.12e-68	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
LEFHLAGG_00919	1.96e-18	-	-	-	M	-	-	-	Glycosyl transferase family 2
LEFHLAGG_00920	8.11e-28	-	-	-	-	-	-	-	-
LEFHLAGG_00921	4.53e-112	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
LEFHLAGG_00922	2.69e-71	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
LEFHLAGG_00923	9.97e-228	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
LEFHLAGG_00924	4.32e-115	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
LEFHLAGG_00925	1.97e-92	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
LEFHLAGG_00926	2.35e-76	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
LEFHLAGG_00927	2.03e-50	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEFHLAGG_00928	1.42e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
LEFHLAGG_00929	1.41e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
LEFHLAGG_00930	2.49e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
LEFHLAGG_00931	4.42e-50	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEFHLAGG_00932	1.22e-89	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
LEFHLAGG_00933	1.37e-146	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
LEFHLAGG_00934	1.51e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
LEFHLAGG_00935	3.8e-121	baeS	-	-	T	-	-	-	Histidine kinase
LEFHLAGG_00936	3.08e-101	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
LEFHLAGG_00937	3.19e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
LEFHLAGG_00938	1.97e-152	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
LEFHLAGG_00939	1.4e-188	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
LEFHLAGG_00940	1.61e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
LEFHLAGG_00941	2.76e-91	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
LEFHLAGG_00942	2.89e-164	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LEFHLAGG_00943	1.49e-207	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEFHLAGG_00944	4.73e-97	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
LEFHLAGG_00945	3.61e-43	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
LEFHLAGG_00946	1.47e-50	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
LEFHLAGG_00947	5.1e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
LEFHLAGG_00948	6.77e-09	-	-	-	S	-	-	-	Putative adhesin
LEFHLAGG_00949	8.46e-23	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
LEFHLAGG_00952	4.13e-296	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEFHLAGG_00953	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
LEFHLAGG_00954	3.27e-130	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
LEFHLAGG_00955	1.28e-211	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LEFHLAGG_00956	3.85e-153	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
LEFHLAGG_00957	1.26e-132	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
LEFHLAGG_00958	2.4e-201	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEFHLAGG_00959	1.12e-168	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
LEFHLAGG_00960	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
LEFHLAGG_00961	8.15e-138	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_00962	3.54e-87	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
LEFHLAGG_00963	1.14e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEFHLAGG_00964	2.49e-285	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEFHLAGG_00965	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEFHLAGG_00966	2.22e-131	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
LEFHLAGG_00967	8.2e-70	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEFHLAGG_00968	6.01e-60	-	-	-	C	-	-	-	Flavodoxin
LEFHLAGG_00969	6.84e-75	yphH	-	-	S	-	-	-	Cupin domain
LEFHLAGG_00970	5.1e-60	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
LEFHLAGG_00971	3.6e-177	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
LEFHLAGG_00972	6.96e-134	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
LEFHLAGG_00973	1.87e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEFHLAGG_00974	6.39e-120	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
LEFHLAGG_00975	3.22e-168	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
LEFHLAGG_00976	2e-107	-	-	-	C	-	-	-	nitroreductase
LEFHLAGG_00977	1.53e-106	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
LEFHLAGG_00978	2.34e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
LEFHLAGG_00979	1.16e-211	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEFHLAGG_00980	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
LEFHLAGG_00981	4.35e-57	-	-	-	V	-	-	-	type I restriction modification DNA specificity domain
LEFHLAGG_00982	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
LEFHLAGG_00983	1.82e-135	pncA	-	-	Q	-	-	-	Isochorismatase family
LEFHLAGG_00984	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEFHLAGG_00985	2.06e-169	-	-	-	F	-	-	-	NUDIX domain
LEFHLAGG_00986	6.06e-181	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
LEFHLAGG_00987	1.08e-10	-	-	-	H	-	-	-	ThiF family
LEFHLAGG_00988	1.61e-169	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
LEFHLAGG_00989	1.28e-45	-	-	-	K	-	-	-	Transcriptional regulator
LEFHLAGG_00990	2.98e-30	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
LEFHLAGG_00991	1.68e-52	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
LEFHLAGG_00992	5.54e-39	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
LEFHLAGG_00993	1.79e-172	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
LEFHLAGG_00995	5.03e-35	-	-	-	-	-	-	-	-
LEFHLAGG_00996	6.56e-176	-	-	-	S	-	-	-	Fic/DOC family
LEFHLAGG_00997	2.83e-58	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
LEFHLAGG_00998	3.96e-37	-	-	-	-	-	-	-	-
LEFHLAGG_00999	1.4e-163	-	-	-	S	-	-	-	protein conserved in bacteria
LEFHLAGG_01000	1.29e-32	-	-	-	-	-	-	-	-
LEFHLAGG_01001	0.0	-	-	-	L	-	-	-	MobA MobL family protein
LEFHLAGG_01002	1.63e-35	-	-	-	-	-	-	-	-
LEFHLAGG_01003	0.0	traA	-	-	L	-	-	-	MobA/MobL family
LEFHLAGG_01004	4.26e-69	-	-	-	-	-	-	-	-
LEFHLAGG_01005	2.15e-138	-	-	-	-	-	-	-	-
LEFHLAGG_01006	5.4e-69	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
LEFHLAGG_01007	1.09e-70	-	-	-	-	-	-	-	-
LEFHLAGG_01008	5.45e-153	-	-	-	-	-	-	-	-
LEFHLAGG_01009	0.0	traE	-	-	U	-	-	-	AAA-like domain
LEFHLAGG_01010	6.3e-286	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
LEFHLAGG_01011	4.77e-269	-	-	-	M	-	-	-	CHAP domain
LEFHLAGG_01012	7.51e-119	-	-	-	-	-	-	-	-
LEFHLAGG_01013	3.28e-105	-	-	-	-	-	-	-	-
LEFHLAGG_01014	0.0	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
LEFHLAGG_01015	2.3e-83	-	-	-	-	-	-	-	-
LEFHLAGG_01016	8.39e-196	-	-	-	-	-	-	-	-
LEFHLAGG_01017	3.87e-83	-	-	-	-	-	-	-	-
LEFHLAGG_01018	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
LEFHLAGG_01019	3.12e-25	-	-	-	-	-	-	-	-
LEFHLAGG_01020	1.74e-57	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
LEFHLAGG_01021	7.33e-248	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LEFHLAGG_01023	1.53e-192	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEFHLAGG_01024	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
LEFHLAGG_01025	3.63e-163	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
LEFHLAGG_01026	1.15e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
LEFHLAGG_01028	1.13e-295	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
LEFHLAGG_01029	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
LEFHLAGG_01030	1.49e-223	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
LEFHLAGG_01031	7.47e-213	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
LEFHLAGG_01032	1.82e-228	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEFHLAGG_01033	3.58e-290	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
LEFHLAGG_01034	9.52e-187	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
LEFHLAGG_01035	2.36e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
LEFHLAGG_01036	2.78e-78	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
LEFHLAGG_01037	3.57e-17	-	-	-	-	-	-	-	-
LEFHLAGG_01038	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
LEFHLAGG_01039	1.13e-280	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
LEFHLAGG_01040	1.39e-111	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
LEFHLAGG_01041	4.7e-192	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LEFHLAGG_01042	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
LEFHLAGG_01043	8.41e-58	cps3F	-	-	-	-	-	-	-
LEFHLAGG_01044	2.22e-108	-	-	-	S	-	-	-	Membrane
LEFHLAGG_01045	0.0	-	-	-	E	-	-	-	Amino acid permease
LEFHLAGG_01046	3.85e-202	cadA	-	-	P	-	-	-	P-type ATPase
LEFHLAGG_01047	1.19e-76	cadA	-	-	P	-	-	-	P-type ATPase
LEFHLAGG_01048	3.51e-146	degV	-	-	S	-	-	-	EDD domain protein, DegV family
LEFHLAGG_01049	2.05e-189	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
LEFHLAGG_01050	1.18e-69	-	-	-	F	-	-	-	glutamine amidotransferase
LEFHLAGG_01051	3.36e-35	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
LEFHLAGG_01052	6.07e-186	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LEFHLAGG_01053	4.22e-171	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LEFHLAGG_01054	4.8e-103	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
LEFHLAGG_01055	2.05e-208	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
LEFHLAGG_01056	8.89e-21	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFHLAGG_01057	4.44e-286	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
LEFHLAGG_01058	2.41e-147	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
LEFHLAGG_01059	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
LEFHLAGG_01060	3.86e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
LEFHLAGG_01061	1.91e-106	lysR5	-	-	K	-	-	-	LysR substrate binding domain
LEFHLAGG_01062	7.53e-72	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
LEFHLAGG_01063	1.47e-14	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEFHLAGG_01064	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
LEFHLAGG_01065	7.88e-87	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
LEFHLAGG_01066	7.55e-308	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
LEFHLAGG_01067	7.95e-263	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEFHLAGG_01068	4.18e-46	-	-	-	-	-	-	-	-
LEFHLAGG_01069	2.59e-189	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
LEFHLAGG_01070	3.51e-74	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
LEFHLAGG_01071	4.03e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
LEFHLAGG_01072	2.22e-39	-	-	-	L	-	-	-	MULE transposase domain
LEFHLAGG_01073	1.2e-94	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
LEFHLAGG_01074	4.18e-75	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
LEFHLAGG_01075	3.13e-35	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
LEFHLAGG_01076	1.59e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
LEFHLAGG_01077	3.12e-202	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
LEFHLAGG_01078	8.14e-62	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
LEFHLAGG_01079	4.72e-66	-	-	-	L	-	-	-	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEFHLAGG_01080	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
LEFHLAGG_01081	1.13e-122	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
LEFHLAGG_01082	8.79e-170	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
LEFHLAGG_01083	1.03e-201	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
LEFHLAGG_01084	8.38e-192	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
LEFHLAGG_01085	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEFHLAGG_01086	4.47e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_01087	4.15e-313	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
LEFHLAGG_01088	2.92e-138	-	-	-	-	-	-	-	-
LEFHLAGG_01092	2.71e-52	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
LEFHLAGG_01093	1.44e-61	-	-	-	-	-	-	-	-
LEFHLAGG_01094	0.0	-	-	-	EGP	-	-	-	Major Facilitator
LEFHLAGG_01095	1.67e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEFHLAGG_01096	6.24e-82	-	-	-	L	-	-	-	Transposase DDE domain group 1
LEFHLAGG_01098	3.81e-288	fusA1	-	-	J	-	-	-	elongation factor G
LEFHLAGG_01099	0.000352	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
LEFHLAGG_01100	2.36e-139	-	-	-	L	-	-	-	PLD-like domain
LEFHLAGG_01101	3.88e-71	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
LEFHLAGG_01102	2.1e-110	-	-	-	L	ko:K07496	-	ko00000	Transposase, IS605 OrfB family
LEFHLAGG_01104	9.27e-56	-	-	-	L	-	-	-	PLD-like domain
LEFHLAGG_01107	7.96e-143	-	-	-	L	-	-	-	Initiator Replication protein
LEFHLAGG_01108	1.34e-45	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
LEFHLAGG_01109	9.24e-76	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
LEFHLAGG_01110	9.14e-109	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
LEFHLAGG_01111	4.04e-47	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LEFHLAGG_01112	1.71e-247	-	-	-	L	-	-	-	Probable transposase
LEFHLAGG_01113	2.08e-33	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LEFHLAGG_01114	3.67e-48	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
LEFHLAGG_01115	2.66e-14	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
LEFHLAGG_01116	2.27e-161	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
LEFHLAGG_01118	2.21e-47	-	-	-	-	-	-	-	-
LEFHLAGG_01119	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
LEFHLAGG_01120	2.91e-53	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
LEFHLAGG_01121	3.7e-24	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
LEFHLAGG_01125	2.07e-157	yvgN	-	-	C	-	-	-	Aldo keto reductase
LEFHLAGG_01126	4.76e-132	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
LEFHLAGG_01127	8.58e-81	-	-	-	S	-	-	-	Sulphur transport
LEFHLAGG_01128	2.82e-24	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
LEFHLAGG_01129	1.94e-147	-	-	-	P	-	-	-	Rhodanese Homology Domain
LEFHLAGG_01131	1.02e-292	prdA	1.21.4.1	-	EJ	ko:K10793	ko00330,map00330	ko00000,ko00001,ko01000	Glycine/sarcosine/betaine reductase component B subunits
LEFHLAGG_01132	1.57e-34	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
LEFHLAGG_01133	5.65e-85	prdB	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a premature stop
LEFHLAGG_01134	2.69e-42	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a premature stop
LEFHLAGG_01135	2.07e-92	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
LEFHLAGG_01136	6.97e-87	-	-	-	EJ	-	-	-	Glycine/sarcosine/betaine reductase component B subunits
LEFHLAGG_01137	8.61e-182	-	5.1.1.4	-	E	ko:K01777	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Proline racemase
LEFHLAGG_01138	5.57e-123	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
LEFHLAGG_01139	1.08e-280	-	-	-	E	-	-	-	amino acid
LEFHLAGG_01140	2.85e-60	yedF	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
LEFHLAGG_01142	3.27e-169	selB	-	-	J	ko:K03833	-	ko00000,ko03012	Elongation factor SelB, winged helix
LEFHLAGG_01143	1.37e-137	-	-	-	E	-	-	-	Serine hydroxymethyltransferase
LEFHLAGG_01144	1.21e-142	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
LEFHLAGG_01145	7.55e-38	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
LEFHLAGG_01146	1.33e-236	-	-	-	C	-	-	-	RnfC Barrel sandwich hybrid domain
LEFHLAGG_01147	4.89e-126	selD	2.7.9.3	-	E	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	AIR synthase related protein, C-terminal domain
LEFHLAGG_01148	1.31e-187	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
LEFHLAGG_01149	4.23e-38	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
LEFHLAGG_01150	6.21e-125	-	-	-	GKT	-	-	-	COG3711 Transcriptional antiterminator
LEFHLAGG_01151	2.26e-43	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	to PTS fructose-specific enzyme IIA component
LEFHLAGG_01152	1.68e-43	-	-	-	G	-	-	-	PTS system, Lactose/Cellobiose specific IIB subunit
LEFHLAGG_01153	3.43e-243	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
LEFHLAGG_01154	5.08e-148	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
LEFHLAGG_01155	9.92e-121	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
LEFHLAGG_01157	1.52e-96	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
LEFHLAGG_01158	5.61e-113	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LEFHLAGG_01159	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEFHLAGG_01160	3.8e-28	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
LEFHLAGG_01161	1.11e-73	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
LEFHLAGG_01163	2.76e-73	-	-	-	S	-	-	-	COG NOG19168 non supervised orthologous group
LEFHLAGG_01164	1.35e-230	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
LEFHLAGG_01165	4.51e-64	-	-	-	S	-	-	-	Membrane
LEFHLAGG_01166	5.12e-94	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
LEFHLAGG_01167	5.46e-238	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
LEFHLAGG_01168	7.29e-272	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LEFHLAGG_01169	8.21e-53	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
LEFHLAGG_01170	5.79e-276	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
LEFHLAGG_01171	9.17e-141	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
LEFHLAGG_01172	6.63e-139	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
LEFHLAGG_01173	3.69e-47	-	-	-	S	-	-	-	EVIDENCE BY HOMOLOGY BIO14.03 Phage related functions and prophages
LEFHLAGG_01176	3.2e-86	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
LEFHLAGG_01177	5.04e-19	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LEFHLAGG_01179	5.4e-65	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
LEFHLAGG_01181	3.85e-36	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
LEFHLAGG_01182	1.42e-104	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
LEFHLAGG_01183	2.14e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
LEFHLAGG_01184	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
LEFHLAGG_01185	0.0	-	-	-	V	-	-	-	restriction
LEFHLAGG_01186	0.0	-	-	-	S	-	-	-	TIGR02687 family
LEFHLAGG_01187	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
LEFHLAGG_01188	1.94e-55	-	-	-	-	-	-	-	-
LEFHLAGG_01189	1.61e-49	-	-	-	-	-	-	-	-
LEFHLAGG_01192	1.95e-16	-	-	-	-	-	-	-	-
LEFHLAGG_01195	3.19e-160	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
LEFHLAGG_01196	1.17e-185	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
LEFHLAGG_01197	1.06e-145	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LEFHLAGG_01198	1.87e-74	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
LEFHLAGG_01199	2.45e-104	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
LEFHLAGG_01200	1.38e-59	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
LEFHLAGG_01202	1e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEFHLAGG_01203	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
LEFHLAGG_01204	1.75e-34	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
LEFHLAGG_01205	3.75e-139	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
LEFHLAGG_01206	4.59e-16	-	-	-	S	-	-	-	YjcQ protein
LEFHLAGG_01207	1.22e-66	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
LEFHLAGG_01208	5.1e-121	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
LEFHLAGG_01209	5e-161	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
LEFHLAGG_01210	1.79e-54	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
LEFHLAGG_01211	2.98e-89	-	-	-	L	ko:K07498	-	ko00000	Transposase IS66 family
LEFHLAGG_01212	1.13e-34	-	-	-	L	ko:K07498	-	ko00000	Transposase
LEFHLAGG_01213	4.01e-44	-	-	-	P	-	-	-	Heavy-metal-associated domain
LEFHLAGG_01214	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
LEFHLAGG_01215	4.88e-28	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
LEFHLAGG_01216	6.24e-101	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
LEFHLAGG_01217	7.6e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
LEFHLAGG_01218	3.07e-124	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
LEFHLAGG_01219	6.52e-90	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
LEFHLAGG_01220	2.58e-177	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
LEFHLAGG_01221	3.49e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
LEFHLAGG_01222	3.96e-269	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
LEFHLAGG_01223	3.46e-174	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEFHLAGG_01224	2.06e-90	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LEFHLAGG_01225	4.43e-181	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
LEFHLAGG_01229	1.98e-128	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
LEFHLAGG_01230	6.5e-90	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
LEFHLAGG_01231	1.75e-99	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
LEFHLAGG_01232	1.54e-73	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFHLAGG_01233	1.11e-66	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
LEFHLAGG_01234	6.88e-100	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
LEFHLAGG_01235	6.66e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LEFHLAGG_01236	1.01e-99	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
LEFHLAGG_01237	2.28e-34	-	-	-	-	-	-	-	-
LEFHLAGG_01238	3.76e-18	-	-	-	-	-	-	-	-
LEFHLAGG_01239	4.33e-141	rssA	-	-	S	-	-	-	Phospholipase, patatin family
LEFHLAGG_01240	5.49e-175	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEFHLAGG_01241	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
LEFHLAGG_01242	6.68e-64	-	-	-	S	-	-	-	VIT family
LEFHLAGG_01243	1.66e-72	-	-	-	L	ko:K07487	-	ko00000	Transposase DDE domain
LEFHLAGG_01244	9.19e-304	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
LEFHLAGG_01245	1.9e-52	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
LEFHLAGG_01246	4.87e-183	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEFHLAGG_01247	2.85e-177	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
LEFHLAGG_01248	1.5e-147	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
LEFHLAGG_01249	1.82e-280	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
LEFHLAGG_01250	2.3e-174	-	-	-	P	-	-	-	Voltage gated chloride channel
LEFHLAGG_01251	3.83e-36	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
LEFHLAGG_01252	3.83e-173	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
LEFHLAGG_01253	3.36e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
LEFHLAGG_01254	1.16e-82	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
LEFHLAGG_01255	2.21e-47	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
LEFHLAGG_01256	1.48e-173	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
LEFHLAGG_01257	4.75e-107	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
LEFHLAGG_01258	7.01e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
LEFHLAGG_01259	3.75e-05	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
LEFHLAGG_01260	8.15e-95	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
LEFHLAGG_01261	1.37e-140	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
LEFHLAGG_01262	8.86e-27	-	-	-	M	-	-	-	by MetaGeneAnnotator
LEFHLAGG_01264	2.48e-05	-	-	-	S	-	-	-	Phage minor structural protein GP20
LEFHLAGG_01265	3.08e-19	-	-	-	S	-	-	-	YjcQ protein
LEFHLAGG_01267	1.9e-35	-	-	-	S	-	-	-	Phage minor capsid protein 2
LEFHLAGG_01268	1.62e-89	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
LEFHLAGG_01269	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
LEFHLAGG_01271	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
LEFHLAGG_01272	4.26e-90	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
LEFHLAGG_01275	4.09e-104	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
LEFHLAGG_01276	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LEFHLAGG_01277	3.29e-07	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LEFHLAGG_01285	8.28e-64	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
LEFHLAGG_01286	1.13e-70	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
LEFHLAGG_01294	1.03e-21	ps105	-	-	-	-	-	-	-
LEFHLAGG_01295	4.54e-50	blpT	-	-	-	-	-	-	-
LEFHLAGG_01296	4.09e-78	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
LEFHLAGG_01297	3.88e-18	-	-	-	-	-	-	-	-
LEFHLAGG_01299	1.08e-51	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
LEFHLAGG_01300	2.66e-102	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
LEFHLAGG_01301	1.6e-86	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
LEFHLAGG_01302	1.42e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
LEFHLAGG_01303	1.05e-143	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LEFHLAGG_01304	3.16e-95	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
LEFHLAGG_01305	2.39e-258	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEFHLAGG_01306	1.33e-192	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEFHLAGG_01307	6.2e-75	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
LEFHLAGG_01308	3.59e-69	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
LEFHLAGG_01309	4.67e-116	nanK	-	-	GK	-	-	-	ROK family
LEFHLAGG_01310	1.03e-160	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
LEFHLAGG_01311	2.61e-117	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LEFHLAGG_01312	9.71e-97	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
LEFHLAGG_01313	7.43e-80	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
LEFHLAGG_01314	4.72e-271	potE	-	-	E	-	-	-	Amino Acid
LEFHLAGG_01315	5.75e-09	-	-	-	-	-	-	-	-
LEFHLAGG_01316	1.82e-41	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEFHLAGG_01317	1.43e-225	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
LEFHLAGG_01318	4.62e-62	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
LEFHLAGG_01319	5.49e-230	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEFHLAGG_01320	5.08e-160	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, N-terminal domain
LEFHLAGG_01321	2.62e-38	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
LEFHLAGG_01322	2.61e-292	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
LEFHLAGG_01323	1.9e-62	yulB	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
LEFHLAGG_01324	3.15e-127	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
LEFHLAGG_01325	7.61e-10	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
LEFHLAGG_01326	2.21e-114	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
LEFHLAGG_01327	4.26e-63	-	-	-	L	-	-	-	Helix-turn-helix domain
LEFHLAGG_01330	1.38e-165	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
LEFHLAGG_01331	3.09e-234	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEFHLAGG_01332	5.54e-199	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
LEFHLAGG_01333	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
LEFHLAGG_01334	1.11e-149	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEFHLAGG_01336	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
LEFHLAGG_01337	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEFHLAGG_01338	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEFHLAGG_01339	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEFHLAGG_01340	3.15e-29	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
LEFHLAGG_01341	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEFHLAGG_01342	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEFHLAGG_01343	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEFHLAGG_01344	1.9e-116	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LEFHLAGG_01345	1.11e-105	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
LEFHLAGG_01346	1.21e-145	vanR	-	-	K	-	-	-	response regulator
LEFHLAGG_01347	7.5e-191	hpk31	-	-	T	-	-	-	Histidine kinase
LEFHLAGG_01348	3.59e-114	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
LEFHLAGG_01349	2.38e-189	-	-	-	G	-	-	-	Transporter, major facilitator family protein
LEFHLAGG_01350	3.15e-277	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEFHLAGG_01351	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_01352	4.44e-44	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEFHLAGG_01353	2.17e-278	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_01354	6.79e-317	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
LEFHLAGG_01355	1.29e-11	-	-	-	-	-	-	-	-
LEFHLAGG_01356	5.29e-59	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
LEFHLAGG_01357	1.34e-66	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
LEFHLAGG_01358	1.63e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
LEFHLAGG_01359	1.77e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
LEFHLAGG_01361	0.0	-	-	-	L	-	-	-	DNA helicase
LEFHLAGG_01362	1.12e-159	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEFHLAGG_01363	2.82e-217	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
LEFHLAGG_01364	1.13e-128	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
LEFHLAGG_01365	1.19e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
LEFHLAGG_01366	5.19e-130	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
LEFHLAGG_01367	5.39e-40	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEFHLAGG_01368	1.33e-55	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
LEFHLAGG_01369	1.08e-190	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
LEFHLAGG_01370	2.27e-162	-	-	-	-	-	-	-	-
LEFHLAGG_01371	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEFHLAGG_01372	4.9e-131	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
LEFHLAGG_01373	4.87e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEFHLAGG_01374	1.54e-168	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEFHLAGG_01375	1.9e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
LEFHLAGG_01376	2.57e-113	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
LEFHLAGG_01377	6.74e-172	arcT	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
LEFHLAGG_01378	5.91e-61	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
LEFHLAGG_01379	2.07e-147	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEFHLAGG_01380	2.45e-192	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
LEFHLAGG_01381	1.93e-253	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
LEFHLAGG_01382	3.94e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
LEFHLAGG_01383	4.71e-188	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
LEFHLAGG_01384	1.35e-159	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEFHLAGG_01385	1.11e-135	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
LEFHLAGG_01387	6.82e-235	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEFHLAGG_01388	5.12e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
LEFHLAGG_01389	7.37e-175	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
LEFHLAGG_01390	2.7e-71	-	-	-	EGP	-	-	-	Transmembrane secretion effector
LEFHLAGG_01391	5.57e-257	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEFHLAGG_01392	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEFHLAGG_01393	1.6e-27	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEFHLAGG_01395	1.94e-139	dkgB	-	-	S	-	-	-	reductase
LEFHLAGG_01396	1.82e-33	-	-	-	-	-	-	-	-
LEFHLAGG_01397	2.27e-98	-	-	-	F	-	-	-	Phosphorylase superfamily
LEFHLAGG_01398	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
LEFHLAGG_01399	8.22e-79	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
LEFHLAGG_01400	4.06e-123	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEFHLAGG_01401	2.31e-151	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
LEFHLAGG_01402	4.73e-110	-	-	-	S	-	-	-	overlaps another CDS with the same product name
LEFHLAGG_01404	2.18e-60	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
LEFHLAGG_01406	1.9e-26	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	PIF1-like helicase
LEFHLAGG_01408	9.38e-91	-	-	-	-	-	-	-	-
LEFHLAGG_01409	4.5e-24	-	-	-	-	-	-	-	-
LEFHLAGG_01410	7.49e-133	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
LEFHLAGG_01411	8.71e-112	-	-	-	S	-	-	-	hydrolase
LEFHLAGG_01412	8.48e-262	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
LEFHLAGG_01413	1.65e-108	-	-	-	F	-	-	-	glutamine amidotransferase
LEFHLAGG_01414	7.25e-32	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
LEFHLAGG_01415	1.75e-57	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEFHLAGG_01416	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEFHLAGG_01418	4.42e-253	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEFHLAGG_01419	4.54e-239	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEFHLAGG_01420	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
LEFHLAGG_01421	2.6e-78	-	-	-	-	-	-	-	-
LEFHLAGG_01422	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
LEFHLAGG_01424	1.79e-98	-	-	-	S	-	-	-	Cell surface protein
LEFHLAGG_01427	1.01e-229	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
LEFHLAGG_01428	2.19e-81	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
LEFHLAGG_01429	1.15e-224	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEFHLAGG_01430	1.32e-282	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEFHLAGG_01431	6.07e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEFHLAGG_01432	1.08e-181	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEFHLAGG_01434	5e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
LEFHLAGG_01435	1.22e-114	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
LEFHLAGG_01436	1.55e-194	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
LEFHLAGG_01437	1.8e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
LEFHLAGG_01438	1.66e-74	-	-	-	-	-	-	-	-
LEFHLAGG_01439	5.9e-52	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
LEFHLAGG_01440	3.16e-30	-	-	-	S	-	-	-	Cytochrome B5
LEFHLAGG_01442	1.12e-79	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
LEFHLAGG_01443	5.45e-243	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEFHLAGG_01444	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
LEFHLAGG_01445	2.86e-135	yueF	-	-	S	-	-	-	AI-2E family transporter
LEFHLAGG_01446	1.55e-200	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
LEFHLAGG_01447	2.79e-146	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LEFHLAGG_01448	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LEFHLAGG_01449	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
LEFHLAGG_01450	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
LEFHLAGG_01451	2.26e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
LEFHLAGG_01452	4.34e-225	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEFHLAGG_01453	1.26e-207	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
LEFHLAGG_01454	6.01e-253	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
LEFHLAGG_01455	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
LEFHLAGG_01456	4.68e-131	-	-	-	G	-	-	-	MucBP domain
LEFHLAGG_01457	3.55e-31	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
LEFHLAGG_01458	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
LEFHLAGG_01459	1.5e-22	-	-	-	-	-	-	-	-
LEFHLAGG_01460	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
LEFHLAGG_01461	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEFHLAGG_01462	1.8e-203	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
LEFHLAGG_01463	1.3e-163	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
LEFHLAGG_01464	4.14e-164	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEFHLAGG_01465	3.45e-36	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
LEFHLAGG_01466	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEFHLAGG_01468	3.79e-259	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease)
LEFHLAGG_01469	1.16e-111	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_01470	1.47e-31	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFHLAGG_01471	1.03e-259	-	-	-	M	-	-	-	Collagen binding domain
LEFHLAGG_01472	4.04e-124	-	-	-	S	-	-	-	Serine hydrolase
LEFHLAGG_01473	5.05e-34	-	-	-	-	-	-	-	-
LEFHLAGG_01476	1.78e-273	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
LEFHLAGG_01477	2.08e-99	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEFHLAGG_01478	4.48e-60	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
LEFHLAGG_01479	5.61e-39	-	-	-	-	-	-	-	-
LEFHLAGG_01480	8.35e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
LEFHLAGG_01481	2.32e-37	-	-	-	E	-	-	-	Zn peptidase
LEFHLAGG_01482	5.02e-39	-	-	-	K	-	-	-	Helix-turn-helix domain
LEFHLAGG_01485	9.37e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
LEFHLAGG_01486	3.59e-136	-	-	-	K	-	-	-	ORF6N domain
LEFHLAGG_01491	2.81e-205	-	-	-	D	-	-	-	AAA domain
LEFHLAGG_01492	5.03e-131	-	-	-	S	-	-	-	AAA domain
LEFHLAGG_01493	5.19e-66	-	-	-	-	-	-	-	-
LEFHLAGG_01494	1.33e-51	-	-	-	-	-	-	-	-
LEFHLAGG_01495	1.5e-104	-	-	-	-	-	-	-	-
LEFHLAGG_01496	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
LEFHLAGG_01497	0.0	-	-	-	L	-	-	-	Primase C terminal 2 (PriCT-2)
LEFHLAGG_01498	3.24e-58	-	-	-	S	-	-	-	magnesium ion binding
LEFHLAGG_01508	6.89e-35	-	-	-	-	-	-	-	-
LEFHLAGG_01509	1.84e-207	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
LEFHLAGG_01510	1.25e-175	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
LEFHLAGG_01511	2.36e-116	-	-	-	S	-	-	-	Phage minor capsid protein 2
LEFHLAGG_01513	2.08e-26	-	-	-	S	-	-	-	Phage minor structural protein GP20
LEFHLAGG_01514	3.55e-124	-	-	-	S	-	-	-	T=7 icosahedral viral capsid
LEFHLAGG_01516	1.39e-39	-	-	-	S	-	-	-	Minor capsid protein
LEFHLAGG_01519	4.29e-49	-	-	-	N	-	-	-	domain, Protein
LEFHLAGG_01521	4.44e-49	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
LEFHLAGG_01522	4.73e-114	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
LEFHLAGG_01524	5.5e-118	-	-	-	M	-	-	-	Prophage endopeptidase tail
LEFHLAGG_01526	1.36e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
LEFHLAGG_01531	3.49e-27	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
LEFHLAGG_01532	1.44e-146	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
LEFHLAGG_01533	3.07e-61	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LEFHLAGG_01534	1.51e-84	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
LEFHLAGG_01535	1.66e-286	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
LEFHLAGG_01536	1.01e-53	yjbH	-	-	Q	-	-	-	Thioredoxin
LEFHLAGG_01537	3.68e-117	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
LEFHLAGG_01538	2.58e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
LEFHLAGG_01539	1.35e-154	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
LEFHLAGG_01540	7.48e-147	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEFHLAGG_01541	1.06e-147	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEFHLAGG_01542	2.26e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
LEFHLAGG_01543	1.21e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
LEFHLAGG_01544	1.39e-100	-	-	-	S	-	-	-	VIT family
LEFHLAGG_01545	2.71e-107	-	-	-	S	-	-	-	membrane
LEFHLAGG_01546	1.97e-53	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
LEFHLAGG_01547	8.68e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
LEFHLAGG_01548	5.61e-46	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
LEFHLAGG_01549	3.43e-96	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEFHLAGG_01551	2.16e-14	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEFHLAGG_01553	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
LEFHLAGG_01554	3.45e-200	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
LEFHLAGG_01555	2.25e-52	-	-	-	S	-	-	-	VanZ like family
LEFHLAGG_01556	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
LEFHLAGG_01557	1.16e-129	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEFHLAGG_01558	2.24e-152	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
LEFHLAGG_01559	7.88e-122	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
LEFHLAGG_01560	4.34e-36	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
LEFHLAGG_01561	7.13e-18	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
LEFHLAGG_01565	1.41e-123	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
LEFHLAGG_01566	1.22e-238	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
LEFHLAGG_01567	9.2e-73	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
LEFHLAGG_01568	4.29e-77	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
LEFHLAGG_01569	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEFHLAGG_01570	4.54e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
LEFHLAGG_01571	1.08e-117	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
LEFHLAGG_01572	4.05e-119	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
LEFHLAGG_01573	2.55e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
LEFHLAGG_01576	3.67e-226	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEFHLAGG_01577	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
LEFHLAGG_01578	6.58e-245	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
LEFHLAGG_01579	2.44e-244	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
LEFHLAGG_01580	1.07e-07	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
LEFHLAGG_01581	8.34e-22	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
LEFHLAGG_01582	3.62e-103	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEFHLAGG_01583	5.08e-241	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
LEFHLAGG_01585	5.97e-49	-	-	-	-	-	-	-	-
LEFHLAGG_01586	2.66e-86	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEFHLAGG_01587	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
LEFHLAGG_01588	1.22e-128	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEFHLAGG_01589	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEFHLAGG_01590	5.99e-131	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
LEFHLAGG_01591	2.21e-125	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
LEFHLAGG_01592	4.97e-248	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEFHLAGG_01593	1.16e-60	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEFHLAGG_01594	3.25e-84	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEFHLAGG_01595	7.21e-275	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
LEFHLAGG_01596	3.3e-160	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEFHLAGG_01597	3e-130	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
LEFHLAGG_01598	7.35e-140	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
LEFHLAGG_01599	1.89e-291	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEFHLAGG_01600	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
LEFHLAGG_01601	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEFHLAGG_01602	1.05e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
LEFHLAGG_01603	4.39e-59	ykuL	-	-	S	-	-	-	CBS domain
LEFHLAGG_01604	3.44e-92	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEFHLAGG_01605	5.76e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEFHLAGG_01606	6.51e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
LEFHLAGG_01608	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
LEFHLAGG_01609	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
LEFHLAGG_01610	2.66e-162	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
LEFHLAGG_01611	7.01e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEFHLAGG_01613	1.1e-68	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
LEFHLAGG_01614	8.15e-122	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_01615	1.12e-87	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
LEFHLAGG_01616	2.39e-125	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
LEFHLAGG_01617	4.74e-130	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEFHLAGG_01618	2.95e-59	ytpP	-	-	CO	-	-	-	Thioredoxin
LEFHLAGG_01619	1.75e-97	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEFHLAGG_01620	3.81e-294	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
LEFHLAGG_01621	2.49e-282	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
LEFHLAGG_01622	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
LEFHLAGG_01623	2.95e-88	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
LEFHLAGG_01624	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEFHLAGG_01625	2.43e-136	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEFHLAGG_01626	3.05e-62	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEFHLAGG_01627	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEFHLAGG_01628	6.94e-95	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
LEFHLAGG_01629	6.97e-138	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
LEFHLAGG_01630	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEFHLAGG_01631	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEFHLAGG_01632	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
LEFHLAGG_01633	5.01e-69	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEFHLAGG_01634	1.92e-90	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
LEFHLAGG_01635	1.03e-229	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
LEFHLAGG_01636	9.56e-41	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
LEFHLAGG_01637	4.98e-99	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEFHLAGG_01638	5.39e-88	yqeK	-	-	H	-	-	-	Hydrolase, HD family
LEFHLAGG_01639	2.79e-65	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEFHLAGG_01640	1.86e-103	-	-	-	H	-	-	-	Nodulation protein S (NodS)
LEFHLAGG_01641	2.55e-152	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
LEFHLAGG_01642	7.44e-72	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
LEFHLAGG_01643	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
LEFHLAGG_01644	9.97e-114	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
LEFHLAGG_01645	4.86e-120	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
LEFHLAGG_01646	6.9e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
LEFHLAGG_01647	1.41e-171	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
LEFHLAGG_01648	4.22e-163	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEFHLAGG_01649	1.82e-49	-	-	-	-	-	-	-	-
LEFHLAGG_01660	3.09e-57	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
LEFHLAGG_01661	4.68e-119	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
LEFHLAGG_01662	6.6e-76	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEFHLAGG_01663	3.15e-200	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEFHLAGG_01664	2.53e-285	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEFHLAGG_01665	3.3e-137	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LEFHLAGG_01667	1.46e-141	csrR	-	-	K	-	-	-	response regulator
LEFHLAGG_01668	1.09e-218	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFHLAGG_01669	1.19e-151	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEFHLAGG_01670	1.6e-24	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
LEFHLAGG_01671	4.75e-170	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
LEFHLAGG_01672	4.27e-143	-	-	-	-	-	-	-	-
LEFHLAGG_01673	1.61e-147	-	-	-	-	-	-	-	-
LEFHLAGG_01674	1.45e-48	-	-	-	S	-	-	-	Protein conserved in bacteria
LEFHLAGG_01675	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEFHLAGG_01676	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
LEFHLAGG_01677	7.18e-47	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEFHLAGG_01678	3.85e-132	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEFHLAGG_01679	3.49e-183	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEFHLAGG_01680	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEFHLAGG_01681	6.23e-104	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
LEFHLAGG_01682	5.17e-153	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
LEFHLAGG_01683	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
LEFHLAGG_01684	4.73e-235	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
LEFHLAGG_01685	1.5e-105	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEFHLAGG_01686	7.41e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
LEFHLAGG_01687	3.98e-36	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
LEFHLAGG_01688	2.28e-118	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
LEFHLAGG_01689	2.16e-58	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
LEFHLAGG_01690	2.95e-86	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
LEFHLAGG_01692	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
LEFHLAGG_01693	2.55e-49	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEFHLAGG_01694	1.11e-90	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
LEFHLAGG_01695	2.47e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
LEFHLAGG_01696	8.22e-203	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
LEFHLAGG_01697	2.92e-60	yqhL	-	-	P	-	-	-	Rhodanese-like protein
LEFHLAGG_01698	6.17e-24	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
LEFHLAGG_01699	6.09e-141	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEFHLAGG_01700	2.22e-257	ynbB	-	-	P	-	-	-	aluminum resistance
LEFHLAGG_01701	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
LEFHLAGG_01702	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
LEFHLAGG_01704	6.13e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEFHLAGG_01705	8.28e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
LEFHLAGG_01706	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
LEFHLAGG_01707	8.26e-105	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEFHLAGG_01708	2.86e-134	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEFHLAGG_01709	1.58e-131	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
LEFHLAGG_01710	2.52e-196	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
LEFHLAGG_01711	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEFHLAGG_01712	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEFHLAGG_01713	1.16e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
LEFHLAGG_01714	3.57e-216	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
LEFHLAGG_01715	3.32e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
LEFHLAGG_01716	4.38e-35	ylxQ	-	-	J	-	-	-	ribosomal protein
LEFHLAGG_01717	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEFHLAGG_01718	6.33e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEFHLAGG_01719	1.16e-151	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEFHLAGG_01720	7.4e-120	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
LEFHLAGG_01721	1.51e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEFHLAGG_01722	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEFHLAGG_01723	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
LEFHLAGG_01724	5.74e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEFHLAGG_01725	1.77e-235	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEFHLAGG_01726	2.71e-168	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEFHLAGG_01728	8.61e-258	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEFHLAGG_01729	7.44e-153	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_01730	1.83e-41	-	-	-	-	-	-	-	-
LEFHLAGG_01731	2.05e-138	ampC	-	-	V	-	-	-	Beta-lactamase
LEFHLAGG_01732	9.35e-141	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
LEFHLAGG_01733	1.79e-278	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
LEFHLAGG_01734	1.19e-111	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
LEFHLAGG_01735	2.09e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEFHLAGG_01736	7.51e-114	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEFHLAGG_01737	1.9e-171	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEFHLAGG_01738	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEFHLAGG_01739	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
LEFHLAGG_01740	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEFHLAGG_01741	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEFHLAGG_01742	1.62e-73	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEFHLAGG_01743	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEFHLAGG_01744	3.29e-181	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEFHLAGG_01745	8.04e-313	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEFHLAGG_01746	6.22e-70	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
LEFHLAGG_01747	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
LEFHLAGG_01748	2.53e-261	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEFHLAGG_01749	2.82e-214	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
LEFHLAGG_01750	3.25e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
LEFHLAGG_01751	6.63e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
LEFHLAGG_01752	8.97e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
LEFHLAGG_01753	9.86e-36	spxA	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
LEFHLAGG_01754	5.39e-120	-	-	-	M	-	-	-	Phosphotransferase enzyme family
LEFHLAGG_01755	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
LEFHLAGG_01756	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEFHLAGG_01757	1.87e-153	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEFHLAGG_01758	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEFHLAGG_01759	1.55e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEFHLAGG_01760	1.38e-192	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEFHLAGG_01761	3.18e-115	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
LEFHLAGG_01762	2.81e-238	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
LEFHLAGG_01763	3.24e-144	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEFHLAGG_01764	6.51e-75	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
LEFHLAGG_01765	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
LEFHLAGG_01766	1.04e-68	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
LEFHLAGG_01767	1.21e-302	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
LEFHLAGG_01768	5.88e-306	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEFHLAGG_01769	7.63e-181	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEFHLAGG_01770	9.72e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEFHLAGG_01771	4.17e-129	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEFHLAGG_01772	3.7e-288	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
LEFHLAGG_01773	1.3e-186	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEFHLAGG_01774	6.15e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEFHLAGG_01775	1.82e-262	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEFHLAGG_01776	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
LEFHLAGG_01777	1.99e-37	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
LEFHLAGG_01778	1.31e-73	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEFHLAGG_01779	2.25e-144	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
LEFHLAGG_01780	2.19e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
LEFHLAGG_01781	2.38e-248	-	-	-	E	ko:K03294	-	ko00000	amino acid
LEFHLAGG_01782	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEFHLAGG_01783	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
LEFHLAGG_01784	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEFHLAGG_01785	7.62e-147	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEFHLAGG_01786	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEFHLAGG_01787	0.000361	-	-	-	S	-	-	-	Tetratricopeptide repeat
LEFHLAGG_01788	9.71e-274	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEFHLAGG_01789	1.94e-245	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEFHLAGG_01790	3.67e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEFHLAGG_01791	3.87e-315	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEFHLAGG_01792	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEFHLAGG_01793	1.72e-29	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
LEFHLAGG_01794	3.51e-33	-	-	-	-	-	-	-	-
LEFHLAGG_01795	1.36e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEFHLAGG_01796	1.34e-22	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
LEFHLAGG_01797	9.47e-27	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
LEFHLAGG_01798	6.09e-96	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
LEFHLAGG_01799	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
LEFHLAGG_01800	1.09e-187	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
LEFHLAGG_01801	7.81e-147	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
LEFHLAGG_01802	2.92e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
LEFHLAGG_01803	2.48e-125	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
LEFHLAGG_01804	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LEFHLAGG_01805	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
LEFHLAGG_01806	6.12e-95	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
LEFHLAGG_01807	3.35e-65	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEFHLAGG_01808	1.04e-166	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
LEFHLAGG_01809	1.74e-122	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
LEFHLAGG_01810	9.14e-41	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEFHLAGG_01811	4.77e-132	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEFHLAGG_01812	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEFHLAGG_01813	3.04e-283	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEFHLAGG_01814	1.63e-173	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
LEFHLAGG_01815	2.83e-95	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEFHLAGG_01816	6.67e-292	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
LEFHLAGG_01817	5.32e-200	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
LEFHLAGG_01818	2.19e-112	-	-	-	S	-	-	-	Acyltransferase family
LEFHLAGG_01826	7.82e-10	-	-	-	K	-	-	-	sequence-specific DNA binding
LEFHLAGG_01828	2.39e-80	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEFHLAGG_01829	3.52e-16	-	-	-	S	-	-	-	Acyltransferase family
LEFHLAGG_01830	1.38e-242	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEFHLAGG_01831	2.58e-156	-	-	-	K	-	-	-	LysR substrate binding domain
LEFHLAGG_01833	6.94e-28	-	-	-	-	-	-	-	-
LEFHLAGG_01834	2.81e-74	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
LEFHLAGG_01835	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
LEFHLAGG_01836	3.64e-63	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
LEFHLAGG_01837	1.71e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
LEFHLAGG_01838	1.56e-187	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
LEFHLAGG_01839	1.79e-134	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
LEFHLAGG_01840	5.34e-143	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LEFHLAGG_01841	2.3e-172	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
LEFHLAGG_01842	5.37e-158	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
LEFHLAGG_01843	1.58e-120	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
LEFHLAGG_01844	2.21e-275	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
LEFHLAGG_01845	1.35e-46	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
LEFHLAGG_01846	2.59e-180	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
LEFHLAGG_01847	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
LEFHLAGG_01848	2.93e-71	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
LEFHLAGG_01849	4.21e-106	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEFHLAGG_01850	6.01e-100	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEFHLAGG_01851	3.06e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEFHLAGG_01852	1.36e-115	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
LEFHLAGG_01853	1.49e-107	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
LEFHLAGG_01854	2.17e-126	-	-	-	M	-	-	-	Glycosyltransferase like family 2
LEFHLAGG_01857	2.08e-148	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEFHLAGG_01858	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
LEFHLAGG_01859	1.87e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
LEFHLAGG_01861	1.91e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
LEFHLAGG_01862	2.2e-141	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEFHLAGG_01863	1.85e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEFHLAGG_01864	1.02e-167	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEFHLAGG_01865	4.6e-223	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_01866	9.05e-76	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
LEFHLAGG_01867	7.86e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEFHLAGG_01868	2.15e-73	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEFHLAGG_01870	1.51e-99	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
LEFHLAGG_01871	3.97e-69	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
LEFHLAGG_01872	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
LEFHLAGG_01873	8.88e-171	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEFHLAGG_01874	1.67e-123	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEFHLAGG_01875	3.94e-106	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
LEFHLAGG_01876	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEFHLAGG_01877	5.77e-264	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LEFHLAGG_01878	9.46e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
LEFHLAGG_01879	3.85e-80	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
LEFHLAGG_01880	2.66e-44	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
LEFHLAGG_01881	2.03e-29	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
LEFHLAGG_01882	3.35e-42	-	-	-	S	-	-	-	Pfam:DUF2276
LEFHLAGG_01883	7.22e-251	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
LEFHLAGG_01884	1.16e-25	csm2	-	-	L	ko:K19138	-	ko00000,ko02048	Csm2 Type III-A
LEFHLAGG_01885	7.7e-88	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
LEFHLAGG_01886	2.62e-79	-	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
LEFHLAGG_01887	1.09e-79	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	RAMP superfamily
LEFHLAGG_01888	1.35e-110	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEFHLAGG_01889	2.56e-42	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEFHLAGG_01890	2.41e-67	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
LEFHLAGG_01891	1.19e-128	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
LEFHLAGG_01892	1.48e-54	-	-	-	S	-	-	-	repeat protein
LEFHLAGG_01893	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEFHLAGG_01894	8.63e-20	-	-	-	-	-	-	-	-
LEFHLAGG_01897	4.02e-110	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEFHLAGG_01898	4.8e-89	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
LEFHLAGG_01899	2.8e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
LEFHLAGG_01900	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEFHLAGG_01901	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEFHLAGG_01902	4.02e-164	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEFHLAGG_01903	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
LEFHLAGG_01904	2e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEFHLAGG_01905	5.6e-17	-	-	-	-	-	-	-	-
LEFHLAGG_01906	1.76e-183	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
LEFHLAGG_01907	6.01e-55	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
LEFHLAGG_01908	1.53e-149	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
LEFHLAGG_01909	8.72e-97	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LEFHLAGG_01910	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEFHLAGG_01911	7.24e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEFHLAGG_01912	8.95e-73	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
LEFHLAGG_01913	4.45e-55	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEFHLAGG_01914	1.69e-164	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
LEFHLAGG_01915	2.49e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEFHLAGG_01916	1.07e-256	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
LEFHLAGG_01917	1.29e-141	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
LEFHLAGG_01918	1.04e-237	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
LEFHLAGG_01919	1.23e-108	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEFHLAGG_01920	1.43e-112	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEFHLAGG_01921	1.34e-172	-	-	-	K	-	-	-	Transcriptional regulator
LEFHLAGG_01922	7.65e-185	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
LEFHLAGG_01923	6.68e-147	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
LEFHLAGG_01924	4.96e-219	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
LEFHLAGG_01925	3.49e-111	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
LEFHLAGG_01927	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEFHLAGG_01928	1.89e-218	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
LEFHLAGG_01929	8.9e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
LEFHLAGG_01930	4.15e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
LEFHLAGG_01931	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
LEFHLAGG_01932	2.15e-51	-	-	-	-	-	-	-	-
LEFHLAGG_01937	1.45e-185	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
LEFHLAGG_01938	1.96e-97	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
LEFHLAGG_01939	3.3e-131	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEFHLAGG_01940	2.9e-231	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
LEFHLAGG_01941	2.84e-62	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
LEFHLAGG_01942	2.44e-174	-	-	-	EG	-	-	-	EamA-like transporter family
LEFHLAGG_01943	6.41e-189	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
LEFHLAGG_01944	1.56e-256	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
LEFHLAGG_01945	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LEFHLAGG_01946	7.18e-173	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
LEFHLAGG_01947	1.34e-220	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
LEFHLAGG_01948	3.98e-162	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEFHLAGG_01949	1.21e-104	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
LEFHLAGG_01951	3.61e-119	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEFHLAGG_01952	3.32e-201	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
LEFHLAGG_01953	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
LEFHLAGG_01954	5.64e-256	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEFHLAGG_01955	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEFHLAGG_01956	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
LEFHLAGG_01957	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
LEFHLAGG_01958	2.41e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEFHLAGG_01959	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
LEFHLAGG_01961	9.22e-53	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
LEFHLAGG_01962	1.38e-106	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEFHLAGG_01963	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEFHLAGG_01964	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEFHLAGG_01965	2.19e-252	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
LEFHLAGG_01966	2.07e-52	-	-	-	K	-	-	-	Transcriptional regulator
LEFHLAGG_01967	1.19e-147	-	-	-	S	-	-	-	EDD domain protein, DegV family
LEFHLAGG_01968	3.9e-91	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
LEFHLAGG_01969	4.48e-52	-	-	-	S	-	-	-	ASCH
LEFHLAGG_01970	1.85e-236	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEFHLAGG_01971	6.64e-97	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
LEFHLAGG_01972	1.03e-116	-	-	-	EG	-	-	-	EamA-like transporter family
LEFHLAGG_01973	3.76e-104	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
LEFHLAGG_01974	3.45e-142	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
LEFHLAGG_01975	3.98e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
LEFHLAGG_01977	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEFHLAGG_01978	1.17e-288	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
LEFHLAGG_01979	1.29e-219	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
LEFHLAGG_01980	2.45e-78	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
LEFHLAGG_01981	1.1e-189	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LEFHLAGG_01982	4.73e-40	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFHLAGG_01983	7.87e-222	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
LEFHLAGG_01984	3.08e-276	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFHLAGG_01986	6.69e-115	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
LEFHLAGG_01987	3.12e-197	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEFHLAGG_01988	8.41e-40	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
LEFHLAGG_01989	1.7e-88	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEFHLAGG_01990	5.08e-197	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
LEFHLAGG_01991	4.22e-106	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
LEFHLAGG_01992	1.02e-111	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
LEFHLAGG_01993	1.12e-15	-	-	-	M	-	-	-	Lysin motif
LEFHLAGG_01994	2e-157	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
LEFHLAGG_01995	1.87e-80	-	-	-	S	-	-	-	Helix-turn-helix domain
LEFHLAGG_01996	6.24e-277	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
LEFHLAGG_01997	3.42e-59	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
LEFHLAGG_01998	1.05e-154	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
LEFHLAGG_01999	3.3e-52	-	-	-	-	-	-	-	-
LEFHLAGG_02000	5.63e-110	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEFHLAGG_02002	7.63e-237	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEFHLAGG_02003	2.93e-262	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEFHLAGG_02004	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
LEFHLAGG_02005	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
LEFHLAGG_02006	2.62e-117	-	-	-	S	-	-	-	Aldo/keto reductase family
LEFHLAGG_02007	3.58e-49	-	-	-	C	-	-	-	Flavodoxin
LEFHLAGG_02008	1.42e-08	-	-	-	P	-	-	-	Putative esterase
LEFHLAGG_02010	7.38e-103	-	-	-	GM	-	-	-	NmrA-like family
LEFHLAGG_02011	5.57e-53	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
LEFHLAGG_02012	5.21e-76	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
LEFHLAGG_02013	9.23e-160	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
LEFHLAGG_02014	1.17e-92	-	-	-	K	-	-	-	Transcriptional regulator
LEFHLAGG_02015	1.88e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
LEFHLAGG_02016	6.12e-90	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEFHLAGG_02017	5.45e-178	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEFHLAGG_02018	2.28e-308	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system