ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
CFHHBMID_00001 3.46e-39 - - - S - - - Belongs to the HesB IscA family
CFHHBMID_00002 1.7e-84 icaB - - G - - - Polysaccharide deacetylase
CFHHBMID_00004 5e-67 - - - K - - - LysR substrate binding domain
CFHHBMID_00005 1.17e-152 - - - S - - - Conserved hypothetical protein 698
CFHHBMID_00006 2.06e-253 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
CFHHBMID_00007 1.26e-136 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CFHHBMID_00008 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CFHHBMID_00009 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
CFHHBMID_00010 1.1e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFHHBMID_00011 1.27e-201 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CFHHBMID_00012 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
CFHHBMID_00013 6.86e-193 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFHHBMID_00014 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFHHBMID_00015 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFHHBMID_00016 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
CFHHBMID_00017 6.48e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CFHHBMID_00018 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFHHBMID_00019 1.37e-07 - - - M - - - domain protein
CFHHBMID_00020 4.13e-24 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
CFHHBMID_00021 1.1e-172 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
CFHHBMID_00022 7.32e-146 ddh 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFHHBMID_00023 2.33e-82 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
CFHHBMID_00024 2.21e-47 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
CFHHBMID_00025 1.89e-173 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
CFHHBMID_00026 7.87e-106 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
CFHHBMID_00027 1.21e-50 srlM1 - - K - - - Glucitol operon activator protein (GutM)
CFHHBMID_00028 7.68e-93 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
CFHHBMID_00029 1.37e-140 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
CFHHBMID_00030 4.44e-55 - - - M - - - by MetaGeneAnnotator
CFHHBMID_00032 1.99e-08 - - - S - - - Phage minor structural protein GP20
CFHHBMID_00034 3.26e-36 - - - S - - - Phage minor capsid protein 2
CFHHBMID_00035 1.07e-125 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
CFHHBMID_00036 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
CFHHBMID_00038 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
CFHHBMID_00039 8.56e-90 - - - L - - - Phage integrase, N-terminal SAM-like domain
CFHHBMID_00045 1.88e-62 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
CFHHBMID_00046 1.24e-69 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
CFHHBMID_00054 5.15e-114 - - - S - - - Haloacid dehalogenase-like hydrolase
CFHHBMID_00055 2.74e-18 - - - - - - - -
CFHHBMID_00057 2.83e-237 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CFHHBMID_00058 3.77e-102 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
CFHHBMID_00059 1.6e-86 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
CFHHBMID_00060 2.02e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
CFHHBMID_00061 2.59e-144 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CFHHBMID_00062 3.86e-96 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
CFHHBMID_00063 4.22e-268 nanB 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
CFHHBMID_00064 8.75e-253 gph - - G ko:K03292 - ko00000 MFS/sugar transport protein
CFHHBMID_00065 4e-229 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
CFHHBMID_00066 7.33e-48 - - - G - - - single-species biofilm formation
CFHHBMID_00067 8.82e-70 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
CFHHBMID_00068 4.76e-113 nanK - - GK - - - ROK family
CFHHBMID_00069 4.39e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
CFHHBMID_00070 5.09e-118 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CFHHBMID_00071 2.33e-95 - - - K - - - Helix-turn-helix domain, rpiR family
CFHHBMID_00072 1.31e-45 yphA - - GM - - - NAD dependent epimerase/dehydratase family
CFHHBMID_00073 1.86e-272 potE - - E - - - Amino Acid
CFHHBMID_00074 1.16e-08 - - - - - - - -
CFHHBMID_00075 5.44e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFHHBMID_00076 4.18e-289 fusA1 - - J - - - elongation factor G
CFHHBMID_00077 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFHHBMID_00078 8.35e-115 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFHHBMID_00079 1.32e-217 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
CFHHBMID_00080 2.92e-151 - 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Alcohol dehydrogenase GroES-like domain
CFHHBMID_00081 5.11e-234 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
CFHHBMID_00082 4.74e-48 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
CFHHBMID_00083 1.06e-51 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CFHHBMID_00084 1.38e-77 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
CFHHBMID_00085 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
CFHHBMID_00086 3.74e-104 - - - L ko:K07497 - ko00000 Integrase core domain
CFHHBMID_00092 6.64e-56 - - - L ko:K07474 - ko00000 Terminase small subunit
CFHHBMID_00093 2.92e-103 yqaT - - S ko:K06909 - ko00000 Phage terminase, large subunit
CFHHBMID_00094 2.46e-131 - - - S - - - Phage portal protein, SPP1 Gp6-like
CFHHBMID_00095 6.34e-89 - - - S - - - Phage Mu protein F like protein
CFHHBMID_00097 1.01e-15 - - - S - - - Domain of unknown function (DUF4355)
CFHHBMID_00100 4.52e-10 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
CFHHBMID_00101 1.02e-37 - - - L - - - Helix-turn-helix domain
CFHHBMID_00103 1.27e-79 - - - S - - - Putative HNHc nuclease
CFHHBMID_00104 2.83e-48 - - - S - - - ERF superfamily
CFHHBMID_00105 5.31e-10 - - - S - - - Bacteriophage Mu Gam like protein
CFHHBMID_00109 1.01e-55 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
CFHHBMID_00112 3.84e-53 - - - L - - - Psort location Cytoplasmic, score
CFHHBMID_00114 1.83e-37 - - - S - - - sequence-specific DNA binding
CFHHBMID_00116 6.92e-26 - - - - - - - -
CFHHBMID_00117 6.48e-26 - - - - - - - -
CFHHBMID_00118 6.18e-18 - - - L - - - Phage integrase, N-terminal SAM-like domain
CFHHBMID_00119 2.11e-72 - - - L - - - Belongs to the 'phage' integrase family
CFHHBMID_00122 1.49e-223 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
CFHHBMID_00123 1.51e-212 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
CFHHBMID_00124 1.35e-230 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CFHHBMID_00125 4.36e-291 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
CFHHBMID_00126 9.52e-187 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
CFHHBMID_00127 2.36e-72 - - - S - - - Protein of unknown function (DUF975)
CFHHBMID_00128 1.57e-77 - - - E - - - GDSL-like Lipase/Acylhydrolase family
CFHHBMID_00129 3.57e-17 - - - - - - - -
CFHHBMID_00130 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
CFHHBMID_00131 7.63e-279 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
CFHHBMID_00132 1.2e-112 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
CFHHBMID_00133 4.7e-192 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CFHHBMID_00134 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
CFHHBMID_00135 3.27e-57 cps3F - - - - - - -
CFHHBMID_00136 2.22e-108 - - - S - - - Membrane
CFHHBMID_00137 0.0 - - - E - - - Amino acid permease
CFHHBMID_00138 5.11e-293 cadA - - P - - - P-type ATPase
CFHHBMID_00140 1.76e-38 rusA - - L - - - Endodeoxyribonuclease RusA
CFHHBMID_00141 6.59e-133 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
CFHHBMID_00147 7.07e-42 - - - S - - - Phage transcriptional regulator, ArpU family
CFHHBMID_00148 4.45e-52 - - - KL - - - DNA methylase
CFHHBMID_00149 3.99e-66 - - - K ko:K12055 - ko00000,ko02044 chromosome segregation
CFHHBMID_00150 1.19e-53 - - - L - - - transposase activity
CFHHBMID_00151 1.26e-181 - - - S - - - Terminase-like family
CFHHBMID_00152 3.75e-165 - - - S - - - Phage portal protein
CFHHBMID_00153 3.18e-84 - - - S - - - Phage Mu protein F like protein
CFHHBMID_00155 5.57e-26 - - - - - - - -
CFHHBMID_00156 6.37e-08 - - - S - - - aminoacyl-tRNA ligase activity
CFHHBMID_00157 5.15e-100 - - - - - - - -
CFHHBMID_00158 1.9e-34 - - - S - - - Phage gp6-like head-tail connector protein
CFHHBMID_00160 5.38e-35 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
CFHHBMID_00161 4.25e-34 - - - S - - - Protein of unknown function (DUF3168)
CFHHBMID_00162 5.51e-86 - - - S - - - Phage major tail protein 2
CFHHBMID_00163 8.96e-34 - - - S - - - Pfam:Phage_TAC_12
CFHHBMID_00164 6.08e-37 - - - - - - - -
CFHHBMID_00165 2e-76 - - - D - - - Phage tail tape measure protein, TP901 family
CFHHBMID_00166 9.68e-63 - - - S - - - phage tail
CFHHBMID_00167 1.46e-93 - - - M - - - Prophage endopeptidase tail
CFHHBMID_00168 6.5e-98 - - - L - - - Replication protein
CFHHBMID_00171 3.51e-146 degV - - S - - - EDD domain protein, DegV family
CFHHBMID_00172 4.81e-188 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
CFHHBMID_00173 3.27e-69 - - - F - - - glutamine amidotransferase
CFHHBMID_00174 1.07e-34 yuxO - - Q - - - Thioesterase superfamily
CFHHBMID_00175 6.07e-186 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFHHBMID_00176 2.41e-175 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CFHHBMID_00177 1.37e-102 - - - S - - - L,D-transpeptidase catalytic domain
CFHHBMID_00178 1.18e-207 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
CFHHBMID_00179 8.89e-21 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFHHBMID_00180 3.64e-285 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CFHHBMID_00181 9.74e-159 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
CFHHBMID_00182 1.39e-42 - - - S - - - Protein of unknown function (DUF1634)
CFHHBMID_00183 3.86e-154 - - - S ko:K07090 - ko00000 membrane transporter protein
CFHHBMID_00184 1.91e-106 lysR5 - - K - - - LysR substrate binding domain
CFHHBMID_00185 1.51e-71 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
CFHHBMID_00187 1.61e-23 - - - L - - - Transposase
CFHHBMID_00188 9.69e-38 - - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
CFHHBMID_00189 5.6e-70 - - - L - - - Phage integrase, N-terminal SAM-like domain
CFHHBMID_00192 6.75e-94 - - - L - - - Lactococcus lactis RepB C-terminus
CFHHBMID_00195 3.19e-59 tnpR1 - - L - - - Resolvase, N terminal domain
CFHHBMID_00196 8.23e-128 - - - L - - - DpnII restriction endonuclease
CFHHBMID_00197 5.24e-121 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
CFHHBMID_00198 2.51e-128 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
CFHHBMID_00199 5.46e-06 - - CBM50 MNU ko:K02395,ko:K19220,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CFHHBMID_00200 1.04e-12 nicK - - L ko:K07467 - ko00000 Replication initiation factor
CFHHBMID_00201 1.17e-148 - - - E - - - lipolytic protein G-D-S-L family
CFHHBMID_00204 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
CFHHBMID_00205 5.56e-87 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
CFHHBMID_00206 3.74e-308 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
CFHHBMID_00207 1.6e-262 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFHHBMID_00211 4.84e-10 - - - - - - - -
CFHHBMID_00214 9.75e-166 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
CFHHBMID_00215 1.08e-234 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CFHHBMID_00216 2.75e-199 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CFHHBMID_00217 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
CFHHBMID_00218 6.07e-152 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CFHHBMID_00220 2.29e-166 - - - E - - - lipolytic protein G-D-S-L family
CFHHBMID_00222 3.74e-122 - - - M - - - hydrolase, family 25
CFHHBMID_00224 5.85e-22 - - - G - - - Peptidase_C39 like family
CFHHBMID_00225 5.45e-24 - - - S - - - Protein of unknown function (DUF3168)
CFHHBMID_00226 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
CFHHBMID_00227 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CFHHBMID_00228 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFHHBMID_00229 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFHHBMID_00230 5.23e-31 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
CFHHBMID_00231 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFHHBMID_00232 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CFHHBMID_00233 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFHHBMID_00238 0.000703 - - - L - - - Helix-turn-helix domain
CFHHBMID_00241 4.67e-117 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CFHHBMID_00242 3.95e-104 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
CFHHBMID_00243 6.98e-145 vanR - - K - - - response regulator
CFHHBMID_00244 2.62e-191 hpk31 - - T - - - Histidine kinase
CFHHBMID_00245 1.02e-113 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
CFHHBMID_00246 2.38e-189 - - - G - - - Transporter, major facilitator family protein
CFHHBMID_00247 1.35e-278 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFHHBMID_00248 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_00249 6.28e-44 - - - K - - - Bacterial regulatory proteins, tetR family
CFHHBMID_00250 1.87e-279 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_00251 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
CFHHBMID_00252 1.29e-11 - - - - - - - -
CFHHBMID_00253 3.05e-58 yyaT - - K ko:K02348 - ko00000 protein acetylation
CFHHBMID_00254 1.2e-67 ymdB - - L - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
CFHHBMID_00255 3.17e-94 lemA - - S ko:K03744 - ko00000 LemA family
CFHHBMID_00256 1.77e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
CFHHBMID_00258 0.0 - - - L - - - DNA helicase
CFHHBMID_00259 2.75e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFHHBMID_00260 1.98e-217 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
CFHHBMID_00261 1.6e-128 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
CFHHBMID_00262 6.86e-105 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
CFHHBMID_00263 1.28e-130 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
CFHHBMID_00264 5.39e-40 - - - K - - - Bacterial regulatory proteins, tetR family
CFHHBMID_00265 5.29e-55 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
CFHHBMID_00266 8.81e-190 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
CFHHBMID_00267 2.27e-162 - - - - - - - -
CFHHBMID_00268 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFHHBMID_00269 3.62e-133 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
CFHHBMID_00270 1.4e-111 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CFHHBMID_00271 5.37e-169 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CFHHBMID_00272 1.9e-31 veg - - S - - - Biofilm formation stimulator VEG
CFHHBMID_00273 1.9e-115 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
CFHHBMID_00274 6.74e-172 arcT - - E - - - Cys/Met metabolism PLP-dependent enzyme
CFHHBMID_00275 5.91e-61 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
CFHHBMID_00276 2.07e-147 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFHHBMID_00277 3.18e-195 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
CFHHBMID_00278 9.57e-254 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
CFHHBMID_00279 3.23e-248 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
CFHHBMID_00280 1.35e-187 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CFHHBMID_00281 1.19e-157 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFHHBMID_00282 5.53e-136 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
CFHHBMID_00283 0.000211 - - - M - - - LPXTG cell wall anchor motif
CFHHBMID_00284 9.68e-235 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFHHBMID_00285 1.79e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
CFHHBMID_00286 7.37e-175 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
CFHHBMID_00287 1.92e-71 - - - EGP - - - Transmembrane secretion effector
CFHHBMID_00288 1.95e-257 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFHHBMID_00289 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFHHBMID_00290 1.11e-25 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFHHBMID_00291 6.77e-140 dkgB - - S - - - reductase
CFHHBMID_00292 1.82e-33 - - - - - - - -
CFHHBMID_00293 1.3e-97 - - - F - - - Phosphorylase superfamily
CFHHBMID_00294 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
CFHHBMID_00304 2.08e-121 - - - - - - - -
CFHHBMID_00305 1.72e-79 ytkL - - S - - - Beta-lactamase superfamily domain
CFHHBMID_00306 2.02e-123 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CFHHBMID_00307 4.53e-156 yibE - - S - - - overlaps another CDS with the same product name
CFHHBMID_00308 4.73e-110 - - - S - - - overlaps another CDS with the same product name
CFHHBMID_00310 6.43e-62 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
CFHHBMID_00312 5.85e-27 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 PIF1-like helicase
CFHHBMID_00314 1.33e-90 - - - - - - - -
CFHHBMID_00315 4.73e-16 - - - - - - - -
CFHHBMID_00316 7.08e-131 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
CFHHBMID_00317 2.15e-112 - - - S - - - hydrolase
CFHHBMID_00318 1.15e-259 ywfO - - S ko:K06885 - ko00000 HD domain protein
CFHHBMID_00319 5.3e-76 - - - S - - - phage tail
CFHHBMID_00320 4.09e-13 - - - D - - - Phage tail tape measure protein
CFHHBMID_00322 4.04e-14 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
CFHHBMID_00324 4.07e-109 - - - F - - - glutamine amidotransferase
CFHHBMID_00325 3.61e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
CFHHBMID_00326 7.06e-57 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CFHHBMID_00327 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CFHHBMID_00329 4.42e-253 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFHHBMID_00330 9.6e-241 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFHHBMID_00331 2.05e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
CFHHBMID_00332 9.11e-79 - - - - - - - -
CFHHBMID_00333 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
CFHHBMID_00335 4.86e-37 - - - D - - - FIVAR domain
CFHHBMID_00337 3.54e-15 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
CFHHBMID_00340 2.26e-60 - - - M - - - Prophage endopeptidase tail
CFHHBMID_00341 4.23e-49 - - - M - - - Prophage endopeptidase tail
CFHHBMID_00342 1.14e-77 - - - S - - - phage tail
CFHHBMID_00343 7.62e-13 - - - D - - - Phage tail tape measure protein
CFHHBMID_00345 1.5e-78 - - - S - - - Cell surface protein
CFHHBMID_00347 7.11e-230 pbuG - - S ko:K06901 - ko00000,ko02000 permease
CFHHBMID_00348 1.77e-80 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
CFHHBMID_00349 5.71e-225 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CFHHBMID_00350 1.32e-282 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CFHHBMID_00351 2.13e-140 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
CFHHBMID_00352 6.63e-148 - - - S - - - Glycosyl transferase family 2
CFHHBMID_00353 4.54e-81 - - - D - - - peptidase
CFHHBMID_00354 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
CFHHBMID_00355 3.57e-75 - - - S - - - Protein of unknown function (DUF1211)
CFHHBMID_00356 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CFHHBMID_00357 2.65e-306 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
CFHHBMID_00358 5.01e-22 yneR - - - - - - -
CFHHBMID_00359 1.45e-289 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFHHBMID_00360 6.47e-285 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
CFHHBMID_00361 2.34e-136 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
CFHHBMID_00362 2.59e-192 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
CFHHBMID_00363 8.43e-12 yobS - - K - - - Bacterial regulatory proteins, tetR family
CFHHBMID_00364 4.44e-141 - - - U ko:K05340 - ko00000,ko02000 sugar transport
CFHHBMID_00365 6.16e-211 - - - S - - - Putative threonine/serine exporter
CFHHBMID_00366 7.29e-89 - - - J - - - Acetyltransferase (GNAT) domain
CFHHBMID_00367 2.33e-121 yicL - - EG - - - EamA-like transporter family
CFHHBMID_00368 2.76e-279 pepF - - E - - - Oligopeptidase F
CFHHBMID_00369 2.04e-137 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
CFHHBMID_00370 1.21e-225 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CFHHBMID_00371 1.78e-172 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
CFHHBMID_00372 1.45e-80 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
CFHHBMID_00373 3.06e-32 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
CFHHBMID_00374 1.59e-218 - - - S - - - Putative peptidoglycan binding domain
CFHHBMID_00375 2.33e-41 - - - K - - - Transcriptional regulator, MarR family
CFHHBMID_00376 2.29e-271 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_00377 6.42e-286 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
CFHHBMID_00378 1e-135 yxeH - - S - - - hydrolase
CFHHBMID_00380 1.29e-219 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
CFHHBMID_00381 2.01e-185 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CFHHBMID_00383 2.43e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
CFHHBMID_00384 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFHHBMID_00385 3.04e-125 yycH - - S - - - YycH protein
CFHHBMID_00386 3.35e-100 yycI - - S - - - YycH protein
CFHHBMID_00387 3.37e-41 - - - S - - - YjbR
CFHHBMID_00388 1.03e-147 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
CFHHBMID_00389 3.5e-189 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
CFHHBMID_00390 1.36e-94 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFHHBMID_00391 1.81e-70 - - - GM - - - NAD(P)H-binding
CFHHBMID_00392 5.2e-34 - - - K - - - MarR family transcriptional regulator
CFHHBMID_00393 1.1e-111 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CFHHBMID_00394 7.92e-58 - - - S - - - PD-(D/E)XK nuclease family transposase
CFHHBMID_00396 1.07e-259 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter
CFHHBMID_00397 1.16e-172 - - - S - - - interspecies interaction between organisms
CFHHBMID_00398 3.56e-20 - - - D - - - GA module
CFHHBMID_00400 1.32e-07 - - - M - - - Glycosyltransferase, group 2 family protein
CFHHBMID_00401 2.37e-34 arbx - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
CFHHBMID_00402 6.97e-188 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
CFHHBMID_00403 8.84e-187 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
CFHHBMID_00404 2.07e-106 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFHHBMID_00405 4.31e-141 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
CFHHBMID_00406 1.5e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CFHHBMID_00407 1.53e-181 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFHHBMID_00409 7.1e-64 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
CFHHBMID_00410 5.25e-116 yunF - - F - - - Protein of unknown function DUF72
CFHHBMID_00411 4.01e-197 yngD - - S ko:K07097 - ko00000 DHHA1 domain
CFHHBMID_00412 7.32e-56 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
CFHHBMID_00413 5.84e-75 - - - - - - - -
CFHHBMID_00414 7.8e-53 ytlR - - I - - - Diacylglycerol kinase catalytic domain
CFHHBMID_00415 3.16e-30 - - - S - - - Cytochrome B5
CFHHBMID_00417 5.61e-80 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
CFHHBMID_00418 3.47e-239 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFHHBMID_00419 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
CFHHBMID_00420 1.42e-135 yueF - - S - - - AI-2E family transporter
CFHHBMID_00421 3.8e-201 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
CFHHBMID_00422 2.07e-143 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CFHHBMID_00423 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFHHBMID_00424 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
CFHHBMID_00425 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
CFHHBMID_00426 3.21e-139 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
CFHHBMID_00427 4.34e-225 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CFHHBMID_00428 1.26e-207 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
CFHHBMID_00429 1.72e-252 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
CFHHBMID_00430 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
CFHHBMID_00431 3.3e-131 - - - G - - - MucBP domain
CFHHBMID_00432 4.34e-32 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
CFHHBMID_00433 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
CFHHBMID_00434 1.5e-22 - - - - - - - -
CFHHBMID_00435 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
CFHHBMID_00436 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFHHBMID_00437 2.56e-203 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
CFHHBMID_00438 7.47e-163 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
CFHHBMID_00439 1.77e-165 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFHHBMID_00440 3.45e-36 ykuJ - - S - - - Protein of unknown function (DUF1797)
CFHHBMID_00441 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CFHHBMID_00450 3.58e-273 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
CFHHBMID_00451 1.53e-61 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CFHHBMID_00452 5.56e-74 coiA - - S ko:K06198 - ko00000 Competence protein
CFHHBMID_00454 8.73e-289 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
CFHHBMID_00455 1.3e-53 yjbH - - Q - - - Thioredoxin
CFHHBMID_00456 8.74e-125 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
CFHHBMID_00457 2.58e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
CFHHBMID_00458 3.87e-154 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
CFHHBMID_00459 7.48e-147 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CFHHBMID_00460 2.61e-148 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CFHHBMID_00461 2.26e-73 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
CFHHBMID_00462 1.21e-188 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
CFHHBMID_00463 1.39e-100 - - - S - - - VIT family
CFHHBMID_00464 2.71e-107 - - - S - - - membrane
CFHHBMID_00465 7.98e-53 - - - K - - - Domain of unknown function (DUF1836)
CFHHBMID_00466 5.92e-83 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
CFHHBMID_00467 3.39e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
CFHHBMID_00468 3.43e-96 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFHHBMID_00470 2.23e-10 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CFHHBMID_00472 9.17e-219 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
CFHHBMID_00473 1.26e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
CFHHBMID_00474 4.81e-54 - - - S - - - VanZ like family
CFHHBMID_00475 4e-153 yebC - - K - - - Transcriptional regulatory protein
CFHHBMID_00476 1.16e-129 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFHHBMID_00477 3.19e-152 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
CFHHBMID_00478 2.25e-121 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
CFHHBMID_00479 3.06e-36 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
CFHHBMID_00480 5.05e-18 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
CFHHBMID_00484 7e-124 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
CFHHBMID_00485 3.13e-239 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
CFHHBMID_00486 1.6e-73 - - - S - - - Calcineurin-like phosphoesterase
CFHHBMID_00487 8.65e-77 yutD - - S - - - Protein of unknown function (DUF1027)
CFHHBMID_00488 1.19e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CFHHBMID_00489 1.14e-38 - - - S - - - Protein of unknown function (DUF1461)
CFHHBMID_00490 3.79e-118 dedA - - S ko:K03975 - ko00000 SNARE associated Golgi protein
CFHHBMID_00491 4.05e-119 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
CFHHBMID_00492 2.55e-65 yugI - - J ko:K07570 - ko00000 general stress protein
CFHHBMID_00495 5.21e-226 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFHHBMID_00496 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
CFHHBMID_00497 6.58e-245 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
CFHHBMID_00498 9.88e-244 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
CFHHBMID_00499 1.01e-77 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CFHHBMID_00500 1.1e-104 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFHHBMID_00501 1.53e-242 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
CFHHBMID_00502 6.36e-268 dam 2.1.1.72 - L ko:K07318 - ko00000,ko01000,ko02048 D12 class N6 adenine-specific DNA methyltransferase
CFHHBMID_00504 1.28e-105 - - - V ko:K07452 - ko00000,ko01000,ko02048 AAA domain (dynein-related subfamily)
CFHHBMID_00505 4.1e-82 - - - S - - - LlaJI restriction endonuclease
CFHHBMID_00508 2.43e-48 - - - - - - - -
CFHHBMID_00509 9.26e-87 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CFHHBMID_00510 1.29e-79 - - - K - - - Transcriptional regulator, MarR family
CFHHBMID_00511 1.22e-128 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFHHBMID_00512 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFHHBMID_00513 8.03e-129 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
CFHHBMID_00514 8.96e-125 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
CFHHBMID_00515 1.17e-246 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CFHHBMID_00516 9.49e-60 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CFHHBMID_00517 4.61e-84 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CFHHBMID_00518 1.45e-274 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
CFHHBMID_00519 2.7e-159 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFHHBMID_00520 2.34e-127 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
CFHHBMID_00521 7.35e-140 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
CFHHBMID_00522 6.61e-292 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFHHBMID_00523 2.1e-305 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
CFHHBMID_00524 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CFHHBMID_00525 1.05e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
CFHHBMID_00526 2.26e-59 ykuL - - S - - - CBS domain
CFHHBMID_00527 3.44e-92 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CFHHBMID_00528 1.65e-223 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CFHHBMID_00529 2.52e-250 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
CFHHBMID_00530 3.77e-35 - - - - - - - -
CFHHBMID_00531 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
CFHHBMID_00532 4.09e-77 - - - T - - - Universal stress protein family
CFHHBMID_00533 6.51e-115 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
CFHHBMID_00535 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CFHHBMID_00536 2.92e-28 yheA - - S - - - Belongs to the UPF0342 family
CFHHBMID_00537 6.56e-163 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
CFHHBMID_00538 7.01e-144 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CFHHBMID_00540 3.15e-69 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
CFHHBMID_00541 4.7e-121 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_00542 1e-88 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
CFHHBMID_00543 1.53e-124 ytmP - - M - - - Choline/ethanolamine kinase
CFHHBMID_00544 4.74e-130 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CFHHBMID_00546 2.95e-59 ytpP - - CO - - - Thioredoxin
CFHHBMID_00547 6.12e-98 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CFHHBMID_00548 2.71e-295 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
CFHHBMID_00549 2.49e-282 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
CFHHBMID_00550 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
CFHHBMID_00551 9.09e-88 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
CFHHBMID_00552 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFHHBMID_00553 4.22e-137 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CFHHBMID_00554 3.05e-62 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CFHHBMID_00555 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFHHBMID_00556 6.98e-98 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
CFHHBMID_00557 4.01e-137 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
CFHHBMID_00558 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFHHBMID_00559 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFHHBMID_00560 4.44e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
CFHHBMID_00561 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFHHBMID_00562 1.92e-90 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
CFHHBMID_00563 1.03e-229 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
CFHHBMID_00564 9.56e-41 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
CFHHBMID_00565 4.98e-99 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFHHBMID_00566 1.88e-88 yqeK - - H - - - Hydrolase, HD family
CFHHBMID_00567 2.79e-65 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CFHHBMID_00568 1.86e-103 - - - H - - - Nodulation protein S (NodS)
CFHHBMID_00569 3.99e-154 ylbM - - S - - - Belongs to the UPF0348 family
CFHHBMID_00570 9.11e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
CFHHBMID_00571 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
CFHHBMID_00572 9.97e-114 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
CFHHBMID_00573 4.86e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
CFHHBMID_00574 6.9e-37 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
CFHHBMID_00575 4.91e-172 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
CFHHBMID_00576 7.31e-164 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFHHBMID_00577 1.82e-49 - - - - - - - -
CFHHBMID_00578 4.68e-119 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
CFHHBMID_00579 1.89e-75 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFHHBMID_00580 1.28e-199 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFHHBMID_00581 3.59e-285 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFHHBMID_00582 9.42e-137 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CFHHBMID_00584 1.46e-141 csrR - - K - - - response regulator
CFHHBMID_00585 1.79e-217 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFHHBMID_00587 6.79e-145 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
CFHHBMID_00588 3.18e-20 - - - S - - - Bacteriophage holin family
CFHHBMID_00589 1.08e-28 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
CFHHBMID_00590 4.27e-143 - - - - - - - -
CFHHBMID_00591 5.64e-148 - - - - - - - -
CFHHBMID_00592 1.45e-48 - - - S - - - Protein conserved in bacteria
CFHHBMID_00593 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFHHBMID_00594 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
CFHHBMID_00595 7.18e-47 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFHHBMID_00596 3.85e-132 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFHHBMID_00597 9.95e-183 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CFHHBMID_00598 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CFHHBMID_00599 8.84e-104 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CFHHBMID_00600 3.23e-124 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
CFHHBMID_00601 5.91e-65 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
CFHHBMID_00602 7.13e-237 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
CFHHBMID_00603 1.29e-106 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFHHBMID_00604 7.41e-41 ynzC - - S - - - UPF0291 protein
CFHHBMID_00605 3.98e-36 yneF - - S ko:K09976 - ko00000 UPF0154 protein
CFHHBMID_00606 3.24e-118 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
CFHHBMID_00607 2.16e-58 - - - S - - - mazG nucleotide pyrophosphohydrolase
CFHHBMID_00608 5.43e-87 yciQ - - P - - - membrane protein (DUF2207)
CFHHBMID_00610 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CFHHBMID_00611 5.52e-51 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFHHBMID_00612 2.24e-90 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
CFHHBMID_00613 2.47e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
CFHHBMID_00614 1.17e-202 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
CFHHBMID_00615 2.92e-60 yqhL - - P - - - Rhodanese-like protein
CFHHBMID_00616 6.17e-24 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
CFHHBMID_00617 1.74e-140 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFHHBMID_00618 2.22e-257 ynbB - - P - - - aluminum resistance
CFHHBMID_00619 1.3e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
CFHHBMID_00620 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
CFHHBMID_00622 2.48e-46 - 2.1.1.63 - H ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFHHBMID_00623 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
CFHHBMID_00624 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
CFHHBMID_00625 2.03e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CFHHBMID_00626 2.86e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFHHBMID_00627 7.84e-132 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
CFHHBMID_00628 1.45e-195 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
CFHHBMID_00629 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CFHHBMID_00630 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFHHBMID_00631 6.68e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
CFHHBMID_00632 8.77e-217 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
CFHHBMID_00633 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
CFHHBMID_00634 7.23e-34 ylxQ - - J - - - ribosomal protein
CFHHBMID_00635 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFHHBMID_00636 6.33e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFHHBMID_00637 2.35e-151 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFHHBMID_00638 1.97e-119 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
CFHHBMID_00639 7.51e-166 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CFHHBMID_00640 3.65e-75 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFHHBMID_00641 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
CFHHBMID_00642 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CFHHBMID_00643 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CFHHBMID_00645 8.61e-258 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CFHHBMID_00646 7.44e-153 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_00647 1.83e-41 - - - - - - - -
CFHHBMID_00648 3.09e-140 ampC - - V - - - Beta-lactamase
CFHHBMID_00649 6.58e-141 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
CFHHBMID_00650 2.09e-277 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
CFHHBMID_00651 1.19e-111 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
CFHHBMID_00652 1.04e-230 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFHHBMID_00653 7.51e-114 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CFHHBMID_00654 1.9e-171 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CFHHBMID_00655 6.26e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFHHBMID_00656 2.33e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
CFHHBMID_00657 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFHHBMID_00658 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFHHBMID_00659 2.82e-74 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFHHBMID_00660 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFHHBMID_00661 3.29e-181 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFHHBMID_00662 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFHHBMID_00663 6.22e-70 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
CFHHBMID_00664 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
CFHHBMID_00665 2.53e-261 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFHHBMID_00666 2.82e-214 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
CFHHBMID_00667 3.25e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
CFHHBMID_00668 6.63e-21 - - - S - - - Protein of unknown function (DUF2969)
CFHHBMID_00669 2.21e-236 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
CFHHBMID_00670 9.86e-36 spxA 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
CFHHBMID_00671 5.1e-118 - - - M - - - Phosphotransferase enzyme family
CFHHBMID_00672 8.34e-132 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
CFHHBMID_00673 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CFHHBMID_00674 3.76e-153 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFHHBMID_00675 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFHHBMID_00676 1.09e-177 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFHHBMID_00677 7.6e-194 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFHHBMID_00678 1.11e-115 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
CFHHBMID_00679 9.86e-239 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
CFHHBMID_00680 1.61e-144 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CFHHBMID_00681 3.74e-74 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
CFHHBMID_00682 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
CFHHBMID_00683 7.35e-69 yloU - - S - - - Asp23 family, cell envelope-related function
CFHHBMID_00684 1.41e-301 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
CFHHBMID_00685 8.2e-308 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFHHBMID_00686 1.54e-180 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CFHHBMID_00687 3.96e-34 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFHHBMID_00688 7.23e-130 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CFHHBMID_00689 2.62e-291 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
CFHHBMID_00690 1.3e-186 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CFHHBMID_00691 6.15e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CFHHBMID_00692 9.04e-263 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFHHBMID_00693 1.32e-55 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
CFHHBMID_00694 1.99e-37 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
CFHHBMID_00695 2.27e-74 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFHHBMID_00696 3.9e-145 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
CFHHBMID_00697 2.19e-78 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
CFHHBMID_00698 3.56e-250 - - - E ko:K03294 - ko00000 amino acid
CFHHBMID_00699 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CFHHBMID_00700 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
CFHHBMID_00701 2.6e-53 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFHHBMID_00702 4.39e-146 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFHHBMID_00703 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFHHBMID_00704 0.00027 - - - S - - - Tetratricopeptide repeat
CFHHBMID_00705 9.71e-274 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFHHBMID_00706 3.92e-245 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CFHHBMID_00707 3.67e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFHHBMID_00708 3.39e-312 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFHHBMID_00709 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFHHBMID_00710 2.09e-30 ykzG - - S - - - Belongs to the UPF0356 family
CFHHBMID_00711 4.97e-33 - - - - - - - -
CFHHBMID_00712 5.54e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CFHHBMID_00713 1.31e-21 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
CFHHBMID_00714 3.42e-31 yktA - - S - - - Belongs to the UPF0223 family
CFHHBMID_00715 1.3e-97 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
CFHHBMID_00716 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
CFHHBMID_00717 3.81e-188 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
CFHHBMID_00718 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
CFHHBMID_00719 2.92e-189 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
CFHHBMID_00720 5.73e-126 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
CFHHBMID_00721 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFHHBMID_00722 2.86e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
CFHHBMID_00723 2.14e-95 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
CFHHBMID_00724 3.35e-65 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFHHBMID_00725 5.17e-167 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
CFHHBMID_00726 6.07e-123 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
CFHHBMID_00727 1.85e-40 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFHHBMID_00728 4.77e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFHHBMID_00729 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFHHBMID_00730 3.04e-283 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFHHBMID_00731 3.45e-175 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
CFHHBMID_00732 6.95e-96 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFHHBMID_00733 9.83e-292 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
CFHHBMID_00734 1.07e-199 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
CFHHBMID_00735 2.25e-137 - - - S - - - Acyltransferase family
CFHHBMID_00736 1.95e-242 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFHHBMID_00737 1.82e-156 - - - K - - - LysR substrate binding domain
CFHHBMID_00739 6.94e-28 - - - - - - - -
CFHHBMID_00740 1.4e-74 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
CFHHBMID_00741 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
CFHHBMID_00742 3.64e-63 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
CFHHBMID_00743 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
CFHHBMID_00744 4.4e-187 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
CFHHBMID_00745 5.11e-134 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
CFHHBMID_00746 4.98e-144 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CFHHBMID_00747 2.3e-172 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
CFHHBMID_00748 2.53e-156 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
CFHHBMID_00749 5.52e-121 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
CFHHBMID_00750 3.55e-274 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
CFHHBMID_00751 5.45e-46 ypmB - - S - - - Protein conserved in bacteria
CFHHBMID_00752 1.05e-179 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
CFHHBMID_00753 3.3e-298 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
CFHHBMID_00754 5.71e-72 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
CFHHBMID_00755 3.11e-108 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFHHBMID_00756 7.32e-101 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFHHBMID_00757 2.51e-159 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFHHBMID_00758 1.93e-115 - - - M - - - transferase activity, transferring glycosyl groups
CFHHBMID_00759 3.67e-108 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
CFHHBMID_00760 7.62e-127 - - - M - - - Glycosyltransferase like family 2
CFHHBMID_00763 2.08e-148 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CFHHBMID_00764 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
CFHHBMID_00765 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
CFHHBMID_00767 5.84e-89 - - - L - - - Phage integrase, N-terminal SAM-like domain
CFHHBMID_00768 2.69e-142 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFHHBMID_00769 1.85e-136 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CFHHBMID_00770 5.86e-167 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CFHHBMID_00771 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_00772 9.58e-201 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFHHBMID_00773 2.15e-73 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CFHHBMID_00775 5.31e-100 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
CFHHBMID_00776 1.97e-69 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
CFHHBMID_00777 1.77e-33 yozE - - S - - - Belongs to the UPF0346 family
CFHHBMID_00778 8.88e-171 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CFHHBMID_00779 1.63e-46 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFHHBMID_00780 9.75e-107 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
CFHHBMID_00781 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFHHBMID_00782 1.42e-264 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFHHBMID_00783 8.77e-10 - - - - - - - -
CFHHBMID_00786 1.42e-93 - - - S ko:K06919 - ko00000 D5 N terminal like
CFHHBMID_00787 5.51e-06 - - - S ko:K06919 - ko00000 D5 N terminal like
CFHHBMID_00788 2.94e-45 - - - L - - - DNA replication protein
CFHHBMID_00795 1.48e-60 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
CFHHBMID_00796 8.42e-11 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
CFHHBMID_00797 3.58e-17 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
CFHHBMID_00798 6.63e-151 - - - L - - - Belongs to the 'phage' integrase family
CFHHBMID_00799 1.56e-255 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
CFHHBMID_00800 9.59e-105 - - - K - - - Bacterial regulatory proteins, tetR family
CFHHBMID_00801 1.59e-165 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
CFHHBMID_00802 1.44e-255 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
CFHHBMID_00803 2.93e-129 pgm - - G - - - Phosphoglycerate mutase family
CFHHBMID_00804 8.95e-50 - - - S - - - repeat protein
CFHHBMID_00805 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CFHHBMID_00806 6.62e-146 int3 - - L - - - Belongs to the 'phage' integrase family
CFHHBMID_00807 5.59e-62 - - - S - - - Domain of unknown function DUF1829
CFHHBMID_00809 1.07e-25 - - - - - - - -
CFHHBMID_00812 9.14e-45 - - - D - - - Anion-transporting ATPase
CFHHBMID_00813 6.54e-15 - - - E - - - Zn peptidase
CFHHBMID_00814 1.16e-44 - - - K - - - Helix-turn-helix domain
CFHHBMID_00815 5.1e-34 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
CFHHBMID_00819 3.29e-109 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFHHBMID_00820 7.94e-88 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
CFHHBMID_00821 3.97e-56 yodB - - K - - - Transcriptional regulator, HxlR family
CFHHBMID_00822 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFHHBMID_00823 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CFHHBMID_00824 9.37e-163 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFHHBMID_00825 4.31e-127 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
CFHHBMID_00826 2e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CFHHBMID_00827 2.24e-16 - - - - - - - -
CFHHBMID_00828 1.24e-183 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
CFHHBMID_00829 4.45e-51 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
CFHHBMID_00830 7.6e-150 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
CFHHBMID_00831 2.15e-97 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CFHHBMID_00832 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFHHBMID_00833 7.24e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CFHHBMID_00834 3.62e-72 yjcF - - J - - - HAD-hyrolase-like
CFHHBMID_00835 4.45e-55 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFHHBMID_00836 1.69e-164 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
CFHHBMID_00837 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFHHBMID_00838 1.07e-256 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
CFHHBMID_00839 1.29e-141 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CFHHBMID_00840 7.36e-238 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
CFHHBMID_00841 1.5e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CFHHBMID_00842 1.43e-112 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFHHBMID_00843 1.83e-172 - - - K - - - Transcriptional regulator
CFHHBMID_00844 7.65e-185 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
CFHHBMID_00845 4.04e-148 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
CFHHBMID_00846 4.96e-219 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CFHHBMID_00847 9.98e-111 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
CFHHBMID_00849 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CFHHBMID_00850 1.55e-217 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
CFHHBMID_00851 6.27e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
CFHHBMID_00852 2.06e-34 - - - S - - - Family of unknown function (DUF5322)
CFHHBMID_00853 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
CFHHBMID_00854 2.15e-51 - - - - - - - -
CFHHBMID_00858 7.69e-272 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CFHHBMID_00859 3.5e-214 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
CFHHBMID_00860 4.13e-185 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
CFHHBMID_00861 6.85e-98 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
CFHHBMID_00862 1.1e-129 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFHHBMID_00863 2.9e-231 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
CFHHBMID_00864 2.81e-89 - - - L - - - DNA alkylation repair enzyme
CFHHBMID_00865 1.72e-174 - - - EG - - - EamA-like transporter family
CFHHBMID_00866 7.86e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
CFHHBMID_00867 1.28e-255 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
CFHHBMID_00868 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CFHHBMID_00869 1.24e-173 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
CFHHBMID_00870 2.71e-220 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
CFHHBMID_00871 4.92e-165 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFHHBMID_00872 1.21e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
CFHHBMID_00874 1.79e-119 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFHHBMID_00875 9.17e-201 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
CFHHBMID_00876 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
CFHHBMID_00877 1.62e-255 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CFHHBMID_00878 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CFHHBMID_00879 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
CFHHBMID_00880 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
CFHHBMID_00881 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CFHHBMID_00882 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
CFHHBMID_00884 6.49e-53 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
CFHHBMID_00885 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CFHHBMID_00886 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CFHHBMID_00887 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CFHHBMID_00888 1.34e-253 FbpA - - K - - - Fibronectin-binding protein
CFHHBMID_00889 2.07e-52 - - - K - - - Transcriptional regulator
CFHHBMID_00890 6.85e-147 - - - S - - - EDD domain protein, DegV family
CFHHBMID_00891 1.94e-91 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
CFHHBMID_00892 7.78e-53 - - - S - - - ASCH
CFHHBMID_00893 7.5e-236 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFHHBMID_00895 8.06e-33 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
CFHHBMID_00896 2.26e-14 - - - S - - - Bacteriophage holin family
CFHHBMID_00897 8.25e-11 - 3.2.1.22 - E ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 lipolytic protein G-D-S-L family
CFHHBMID_00899 1.3e-58 - - - M - - - Prophage endopeptidase tail
CFHHBMID_00900 1.05e-19 - - - S - - - phage tail
CFHHBMID_00901 3.32e-184 - - - S - - - peptidoglycan catabolic process
CFHHBMID_00905 7.27e-40 - - - - - - - -
CFHHBMID_00906 1.24e-30 - - - - - - - -
CFHHBMID_00907 4.43e-12 - - - - - - - -
CFHHBMID_00908 1.82e-125 - - - S - - - Phage capsid family
CFHHBMID_00909 1.09e-67 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Clp protease
CFHHBMID_00910 2.74e-101 - - - S - - - Phage portal protein
CFHHBMID_00911 1.91e-225 - - - S - - - Terminase
CFHHBMID_00912 1.57e-14 - - - S - - - Phage terminase, small subunit
CFHHBMID_00913 1.04e-34 - - - V - - - HNH nucleases
CFHHBMID_00914 4.65e-30 - - - - - - - -
CFHHBMID_00915 0.000106 - - - N - - - PFAM YcfA family protein
CFHHBMID_00916 2.95e-59 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
CFHHBMID_00917 1.04e-48 - - - S - - - Type I restriction modification DNA specificity domain
CFHHBMID_00918 3.96e-171 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
CFHHBMID_00928 1.09e-18 - - - S - - - protein disulfide oxidoreductase activity
CFHHBMID_00933 8.82e-159 yvgN - - C - - - Aldo keto reductase
CFHHBMID_00939 1.99e-23 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
CFHHBMID_00940 8e-53 agrC 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
CFHHBMID_00942 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
CFHHBMID_00943 7.76e-48 - - - - - - - -
CFHHBMID_00945 3.22e-161 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
CFHHBMID_00946 1.32e-20 bglG - - K ko:K03488 - ko00000,ko03000 antiterminator
CFHHBMID_00947 4.56e-78 - - - L - - - Resolvase, N-terminal domain
CFHHBMID_00948 1.45e-120 - - - L - - - Probable transposase
CFHHBMID_00949 4.85e-46 - - - S - - - Replication initiator protein A (RepA) N-terminus
CFHHBMID_00950 9.27e-142 - - - L - - - Initiator Replication protein
CFHHBMID_00952 7.19e-109 sip - - L - - - Belongs to the 'phage' integrase family
CFHHBMID_00953 1.29e-26 - - - - - - - -
CFHHBMID_00954 1.08e-23 - - - - - - - -
CFHHBMID_00955 6.75e-49 - - - E - - - IrrE N-terminal-like domain
CFHHBMID_00956 4.51e-58 - - - K ko:K07727 - ko00000,ko03000 addiction module antidote protein HigA
CFHHBMID_00957 1.65e-19 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
CFHHBMID_00958 1.93e-26 - - - - - - - -
CFHHBMID_00963 2.97e-207 - - - D - - - AAA domain
CFHHBMID_00964 7.51e-133 - - - S - - - AAA domain
CFHHBMID_00965 3.76e-65 - - - - - - - -
CFHHBMID_00966 3.8e-51 - - - - - - - -
CFHHBMID_00967 3.03e-104 - - - - - - - -
CFHHBMID_00968 0.0 - - - L - - - Helicase C-terminal domain protein
CFHHBMID_00969 0.0 - - - L - - - Primase C terminal 2 (PriCT-2)
CFHHBMID_00970 5.62e-59 - - - S - - - magnesium ion binding
CFHHBMID_00976 4.55e-36 - - - S - - - Phage transcriptional regulator, ArpU family
CFHHBMID_00977 3.11e-41 - - - - - - - -
CFHHBMID_00978 7.72e-55 - - - L ko:K07474 - ko00000 Terminase small subunit
CFHHBMID_00979 4.04e-223 yqaT - - S ko:K06909 - ko00000 Phage terminase, large subunit
CFHHBMID_00980 1.94e-64 - - - S - - - Phage portal protein
CFHHBMID_00981 5.58e-108 - - - S - - - Phage Mu protein F like protein
CFHHBMID_00984 3.32e-28 - - - S - - - aminoacyl-tRNA ligase activity
CFHHBMID_00985 2.88e-124 - - - - - - - -
CFHHBMID_00986 1.06e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
CFHHBMID_00987 1.29e-200 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
CFHHBMID_00990 6.68e-47 - - - L - - - recombinase activity
CFHHBMID_00993 3.44e-85 - - - - - - - -
CFHHBMID_00994 3.37e-27 - - - - - - - -
CFHHBMID_00997 5.29e-32 - - - L - - - N-terminal phage replisome organiser (Phage_rep_org_N)
CFHHBMID_00998 1.35e-64 - - - S - - - Putative HNHc nuclease
CFHHBMID_01002 7.05e-97 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
CFHHBMID_01003 1.76e-22 - - - K - - - Helix-turn-helix XRE-family like proteins
CFHHBMID_01005 6.45e-50 - - - K - - - Peptidase S24-like
CFHHBMID_01008 6.36e-72 - - - L - - - Belongs to the 'phage' integrase family
CFHHBMID_01009 2.58e-87 - - - S - - - Calcineurin-like phosphoesterase
CFHHBMID_01010 2.08e-121 - - - EG - - - EamA-like transporter family
CFHHBMID_01011 8.54e-103 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-type Na efflux pump, permease component
CFHHBMID_01012 9.85e-142 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
CFHHBMID_01013 2.01e-26 - - - K - - - Psort location Cytoplasmic, score
CFHHBMID_01015 2.02e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CFHHBMID_01016 1.17e-288 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
CFHHBMID_01017 3.68e-17 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
CFHHBMID_01018 7.87e-75 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphatase family
CFHHBMID_01019 2.34e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CFHHBMID_01020 4.73e-40 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFHHBMID_01021 1.36e-222 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
CFHHBMID_01022 2.17e-276 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFHHBMID_01024 6.69e-115 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
CFHHBMID_01025 6.57e-199 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFHHBMID_01026 5.92e-40 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
CFHHBMID_01027 1.7e-88 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFHHBMID_01028 1.69e-195 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
CFHHBMID_01029 4.22e-106 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
CFHHBMID_01030 4.16e-111 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
CFHHBMID_01031 1.79e-27 - - - M - - - Lysin motif
CFHHBMID_01032 9.24e-156 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
CFHHBMID_01033 2.99e-79 - - - S - - - Helix-turn-helix domain
CFHHBMID_01034 6.24e-277 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
CFHHBMID_01035 7.63e-237 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CFHHBMID_01036 4.42e-264 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CFHHBMID_01037 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
CFHHBMID_01038 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
CFHHBMID_01039 1.52e-134 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
CFHHBMID_01040 1.85e-85 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFHHBMID_01041 1.72e-77 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
CFHHBMID_01042 6.63e-167 - - - L - - - Belongs to the 'phage' integrase family
CFHHBMID_01043 1.43e-84 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
CFHHBMID_01044 2.91e-270 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
CFHHBMID_01045 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
CFHHBMID_01047 6.87e-103 - - - F - - - Hydrolase, nudix family
CFHHBMID_01048 1.34e-73 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
CFHHBMID_01049 1.1e-85 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
CFHHBMID_01050 5.58e-92 - - - M - - - GNAT acetyltransferase
CFHHBMID_01052 1.13e-243 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
CFHHBMID_01053 2.27e-83 ypsA - - S - - - Belongs to the UPF0398 family
CFHHBMID_01054 5.33e-237 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
CFHHBMID_01055 1.17e-98 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CFHHBMID_01056 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
CFHHBMID_01057 6.92e-143 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
CFHHBMID_01058 8.38e-144 yitL - - S ko:K00243 - ko00000 S1 domain
CFHHBMID_01059 1.16e-67 - - - S - - - Protein of unknown function (DUF441)
CFHHBMID_01060 3.09e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CFHHBMID_01061 1.14e-127 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CFHHBMID_01062 3.83e-79 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFHHBMID_01063 2.77e-75 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFHHBMID_01064 6.85e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFHHBMID_01065 6.04e-275 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFHHBMID_01066 4.03e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFHHBMID_01067 1.8e-155 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
CFHHBMID_01068 1.49e-223 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
CFHHBMID_01069 1.18e-125 ytlR - - I - - - Diacylglycerol kinase catalytic domain
CFHHBMID_01070 5.56e-89 - - - - - - - -
CFHHBMID_01072 1.21e-20 - - - - - - - -
CFHHBMID_01073 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
CFHHBMID_01074 6.3e-37 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
CFHHBMID_01075 2.13e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
CFHHBMID_01083 1.05e-82 - - - H - - - Methyltransferase domain
CFHHBMID_01084 7.22e-92 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
CFHHBMID_01085 1.58e-51 - - - M - - - Acetyltransferase (GNAT) family
CFHHBMID_01087 1.51e-30 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
CFHHBMID_01088 2.29e-51 ybbB - - S - - - Protein of unknown function (DUF1211)
CFHHBMID_01090 0.0 - - - L - - - helicase
CFHHBMID_01091 3.86e-69 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
CFHHBMID_01092 3.95e-22 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
CFHHBMID_01093 5.89e-42 - - - S - - - CHY zinc finger
CFHHBMID_01094 1.79e-53 ywnA - - K - - - Transcriptional regulator
CFHHBMID_01095 1.24e-106 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
CFHHBMID_01097 1.72e-52 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Protease synthase and sporulation negative regulatory protein pai 1
CFHHBMID_01098 1.19e-225 rsmF - - J - - - NOL1 NOP2 sun family protein
CFHHBMID_01099 4.12e-82 - - - - - - - -
CFHHBMID_01100 4.55e-105 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
CFHHBMID_01101 5.02e-144 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
CFHHBMID_01102 2.34e-77 yokL3 - - J - - - Acetyltransferase (GNAT) domain
CFHHBMID_01103 4e-240 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CFHHBMID_01104 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
CFHHBMID_01105 4.56e-266 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CFHHBMID_01107 6.33e-78 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
CFHHBMID_01108 5.37e-222 - - - L - - - Helicase C-terminal domain protein
CFHHBMID_01109 8.4e-66 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
CFHHBMID_01110 1.68e-36 - - - T - - - Putative diguanylate phosphodiesterase
CFHHBMID_01111 6.54e-153 - - - T - - - diguanylate cyclase activity
CFHHBMID_01112 0.0 - - - S - - - Bacterial cellulose synthase subunit
CFHHBMID_01113 9.95e-255 ydaM - - M - - - Glycosyl transferase family group 2
CFHHBMID_01114 4.24e-256 - - - S - - - Protein conserved in bacteria
CFHHBMID_01115 1.89e-237 - - - - - - - -
CFHHBMID_01116 6.46e-162 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
CFHHBMID_01117 1.41e-47 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
CFHHBMID_01118 1.59e-184 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
CFHHBMID_01119 2.53e-196 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CFHHBMID_01120 8.12e-133 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
CFHHBMID_01121 6.5e-121 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CFHHBMID_01122 7e-276 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
CFHHBMID_01123 1.34e-254 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CFHHBMID_01124 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
CFHHBMID_01125 1.5e-243 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
CFHHBMID_01126 2.32e-203 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
CFHHBMID_01127 2.17e-48 - - - M - - - LysM domain
CFHHBMID_01128 1.38e-25 - - - P - - - Rhodanese Homology Domain
CFHHBMID_01129 1.32e-185 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
CFHHBMID_01130 2.12e-268 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
CFHHBMID_01131 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFHHBMID_01132 1.95e-229 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
CFHHBMID_01133 1.69e-144 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
CFHHBMID_01134 1.53e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
CFHHBMID_01135 7.12e-68 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
CFHHBMID_01136 1.58e-19 - - - M - - - Glycosyl transferase family 2
CFHHBMID_01137 1.15e-27 - - - - - - - -
CFHHBMID_01138 2.51e-111 - - - S - - - Predicted membrane protein (DUF2207)
CFHHBMID_01139 2.69e-71 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
CFHHBMID_01140 5.23e-230 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
CFHHBMID_01141 1.34e-116 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CFHHBMID_01142 5.62e-92 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
CFHHBMID_01143 4.52e-77 yceE - - S - - - haloacid dehalogenase-like hydrolase
CFHHBMID_01144 1.63e-49 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
CFHHBMID_01145 3.49e-49 - - - S - - - Domain of unknown function (DUF4811)
CFHHBMID_01146 1.41e-246 ycnB - - U - - - Belongs to the major facilitator superfamily
CFHHBMID_01147 2.49e-43 - - - K - - - MerR HTH family regulatory protein
CFHHBMID_01148 1.29e-51 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFHHBMID_01149 3.26e-65 - - - M - - - LysM domain protein
CFHHBMID_01150 1.12e-115 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
CFHHBMID_01151 1.29e-109 - - - C - - - Domain of unknown function (DUF4931)
CFHHBMID_01153 6.49e-90 - - - O - - - ADP-ribosylglycohydrolase
CFHHBMID_01154 6.42e-131 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFHHBMID_01155 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFHHBMID_01156 1.61e-91 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
CFHHBMID_01157 1.88e-102 ylmH - - S - - - S4 domain protein
CFHHBMID_01158 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
CFHHBMID_01159 8.14e-43 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CFHHBMID_01160 4.52e-229 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFHHBMID_01161 6.07e-240 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CFHHBMID_01162 4.55e-76 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CFHHBMID_01163 7.42e-196 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFHHBMID_01164 1.27e-234 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFHHBMID_01165 3.64e-172 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFHHBMID_01166 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CFHHBMID_01167 1.05e-13 ftsL - - D - - - Essential cell division protein
CFHHBMID_01168 3.67e-180 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CFHHBMID_01169 2.65e-82 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
CFHHBMID_01171 5.43e-196 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
CFHHBMID_01172 1.16e-05 - - - S - - - Protein of unknown function (DUF4044)
CFHHBMID_01173 6.26e-123 ybcH - - D ko:K06889 - ko00000 Alpha beta
CFHHBMID_01174 2.65e-137 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
CFHHBMID_01175 1.41e-115 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_01176 3.02e-122 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
CFHHBMID_01177 7.95e-163 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
CFHHBMID_01178 4.14e-97 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CFHHBMID_01179 9.34e-71 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
CFHHBMID_01180 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
CFHHBMID_01181 2.35e-207 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
CFHHBMID_01182 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
CFHHBMID_01183 2.27e-102 radC - - L ko:K03630 - ko00000 DNA repair protein
CFHHBMID_01184 1.21e-169 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
CFHHBMID_01185 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CFHHBMID_01186 1.44e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFHHBMID_01187 1.02e-204 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
CFHHBMID_01188 2.64e-222 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CFHHBMID_01189 3.66e-72 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
CFHHBMID_01190 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFHHBMID_01191 1.03e-31 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
CFHHBMID_01192 1.28e-244 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
CFHHBMID_01194 6.35e-97 uspA - - T - - - universal stress protein
CFHHBMID_01195 5.11e-71 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
CFHHBMID_01196 5.17e-253 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
CFHHBMID_01197 1.39e-156 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
CFHHBMID_01199 3.01e-65 yviA - - S - - - Protein of unknown function (DUF421)
CFHHBMID_01200 2.16e-17 - - - S - - - Protein of unknown function (DUF3290)
CFHHBMID_01201 1.65e-07 - - - S - - - Protein of unknown function (DUF3290)
CFHHBMID_01202 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CFHHBMID_01203 0.0 - - - S - - - membrane
CFHHBMID_01204 3.03e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFHHBMID_01205 1.34e-265 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
CFHHBMID_01206 1.18e-128 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
CFHHBMID_01207 8.7e-179 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CFHHBMID_01209 9.68e-22 - - - - - - - -
CFHHBMID_01210 3.12e-256 oatA - - I - - - Acyltransferase
CFHHBMID_01211 1.65e-272 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFHHBMID_01212 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CFHHBMID_01213 2.44e-178 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFHHBMID_01216 1.04e-52 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
CFHHBMID_01217 8.89e-94 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFHHBMID_01218 3.55e-79 yslB - - S - - - Protein of unknown function (DUF2507)
CFHHBMID_01219 5.23e-54 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
CFHHBMID_01220 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CFHHBMID_01221 3.86e-20 cvpA - - S - - - Colicin V production protein
CFHHBMID_01222 3.67e-17 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CFHHBMID_01223 5.49e-44 yrzB - - S - - - Belongs to the UPF0473 family
CFHHBMID_01224 1.29e-77 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFHHBMID_01225 2.44e-49 yrzL - - S - - - Belongs to the UPF0297 family
CFHHBMID_01226 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFHHBMID_01227 2.13e-236 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CFHHBMID_01228 7.21e-153 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
CFHHBMID_01229 3.5e-18 - - - - - - - -
CFHHBMID_01230 5.55e-184 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFHHBMID_01231 2.56e-91 lutC - - S ko:K00782 - ko00000 LUD domain
CFHHBMID_01232 5.76e-310 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
CFHHBMID_01233 3.54e-150 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
CFHHBMID_01234 2.92e-264 - - - E ko:K03294 - ko00000 Amino Acid
CFHHBMID_01236 3.61e-79 uspA3 - - T - - - universal stress protein
CFHHBMID_01238 1.06e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
CFHHBMID_01239 5.96e-263 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CFHHBMID_01240 2.88e-231 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFHHBMID_01241 1.45e-193 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CFHHBMID_01242 2.19e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CFHHBMID_01243 1.41e-287 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFHHBMID_01244 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFHHBMID_01245 4.38e-256 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
CFHHBMID_01246 1.84e-203 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFHHBMID_01247 2.09e-111 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFHHBMID_01248 1.68e-38 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
CFHHBMID_01249 1.28e-116 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
CFHHBMID_01250 1.71e-185 ymfH - - S - - - Peptidase M16
CFHHBMID_01251 1.04e-136 ymfF - - S - - - Peptidase M16 inactive domain protein
CFHHBMID_01252 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
CFHHBMID_01253 2.62e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CFHHBMID_01254 5e-125 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
CFHHBMID_01255 2.89e-83 - - - J ko:K03976 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
CFHHBMID_01256 1.61e-207 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CFHHBMID_01257 2.44e-250 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CFHHBMID_01258 1.2e-23 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
CFHHBMID_01259 1.08e-163 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
CFHHBMID_01260 1.59e-38 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
CFHHBMID_01261 2.52e-285 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFHHBMID_01262 2.27e-87 ybbR - - S - - - YbbR-like protein
CFHHBMID_01263 1.95e-162 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CFHHBMID_01264 3.92e-92 - - - S - - - Protein of unknown function (DUF1361)
CFHHBMID_01265 4.26e-146 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
CFHHBMID_01266 3.34e-90 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
CFHHBMID_01267 1e-72 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
CFHHBMID_01268 7.01e-181 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
CFHHBMID_01269 1.52e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFHHBMID_01270 1.68e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
CFHHBMID_01271 1.37e-53 - - - - - - - -
CFHHBMID_01272 4.3e-91 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CFHHBMID_01273 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CFHHBMID_01274 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
CFHHBMID_01275 4.45e-224 eriC - - P ko:K03281 - ko00000 chloride
CFHHBMID_01276 5.39e-189 - - - E - - - Major Facilitator Superfamily
CFHHBMID_01277 7.58e-210 yclK - - T - - - Histidine kinase
CFHHBMID_01278 3.94e-134 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
CFHHBMID_01279 8.19e-167 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFHHBMID_01280 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CFHHBMID_01281 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CFHHBMID_01282 4.68e-263 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
CFHHBMID_01283 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CFHHBMID_01284 2.76e-175 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
CFHHBMID_01286 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CFHHBMID_01287 2.05e-191 whiA - - K ko:K09762 - ko00000 May be required for sporulation
CFHHBMID_01288 9.11e-195 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
CFHHBMID_01289 7.15e-161 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
CFHHBMID_01290 5.61e-102 - - - GM - - - NAD dependent epimerase dehydratase family protein
CFHHBMID_01291 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CFHHBMID_01292 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CFHHBMID_01293 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CFHHBMID_01294 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CFHHBMID_01295 3.37e-142 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFHHBMID_01296 2.04e-168 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFHHBMID_01297 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
CFHHBMID_01298 1.44e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
CFHHBMID_01299 1.37e-103 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFHHBMID_01300 1.03e-110 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
CFHHBMID_01301 9.88e-81 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
CFHHBMID_01302 4.56e-207 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFHHBMID_01303 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CFHHBMID_01304 1.95e-119 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
CFHHBMID_01305 7.08e-105 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFHHBMID_01306 4.87e-65 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
CFHHBMID_01307 2.14e-159 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
CFHHBMID_01308 9.24e-201 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
CFHHBMID_01309 0.0 ydaO - - E - - - amino acid
CFHHBMID_01310 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
CFHHBMID_01311 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CFHHBMID_01312 1.7e-46 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFHHBMID_01313 2.02e-41 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
CFHHBMID_01314 1.52e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CFHHBMID_01315 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
CFHHBMID_01316 5.06e-206 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFHHBMID_01317 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CFHHBMID_01318 9.14e-89 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
CFHHBMID_01319 8.09e-178 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
CFHHBMID_01320 9.93e-104 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
CFHHBMID_01321 5.19e-133 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFHHBMID_01322 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
CFHHBMID_01323 1.57e-103 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
CFHHBMID_01324 1.78e-82 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFHHBMID_01325 2.93e-39 yaaL - - S - - - Protein of unknown function (DUF2508)
CFHHBMID_01326 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFHHBMID_01327 1.48e-51 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFHHBMID_01328 1.65e-269 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFHHBMID_01329 3.86e-81 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CFHHBMID_01330 3.89e-97 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
CFHHBMID_01331 1.36e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
CFHHBMID_01332 1.81e-58 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
CFHHBMID_01333 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFHHBMID_01334 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFHHBMID_01335 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFHHBMID_01337 2.18e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CFHHBMID_01338 2.21e-97 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFHHBMID_01339 9.98e-150 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CFHHBMID_01340 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFHHBMID_01341 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
CFHHBMID_01342 3.08e-16 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CFHHBMID_01343 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CFHHBMID_01344 1.93e-92 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
CFHHBMID_01345 2.29e-139 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFHHBMID_01346 3.45e-73 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CFHHBMID_01347 4.55e-263 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
CFHHBMID_01348 7.38e-313 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFHHBMID_01349 1.38e-195 yacL - - S - - - domain protein
CFHHBMID_01350 2.79e-284 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CFHHBMID_01351 3.38e-95 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
CFHHBMID_01352 1.36e-24 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
CFHHBMID_01353 1.04e-280 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
CFHHBMID_01354 2.56e-45 - - - S - - - Enterocin A Immunity
CFHHBMID_01355 4.1e-109 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFHHBMID_01356 4.29e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
CFHHBMID_01357 1.08e-147 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFHHBMID_01359 1.32e-53 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
CFHHBMID_01360 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
CFHHBMID_01361 6.51e-166 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CFHHBMID_01362 3.1e-307 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFHHBMID_01363 3.32e-113 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CFHHBMID_01364 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
CFHHBMID_01365 6.07e-115 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFHHBMID_01368 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
CFHHBMID_01369 1.14e-119 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
CFHHBMID_01370 2.24e-16 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
CFHHBMID_01371 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
CFHHBMID_01372 3.03e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
CFHHBMID_01373 1.24e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
CFHHBMID_01374 5.64e-69 gtcA - - S - - - Teichoic acid glycosylation protein
CFHHBMID_01375 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
CFHHBMID_01376 2.62e-213 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CFHHBMID_01377 8.6e-230 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
CFHHBMID_01378 0.0 - - - E - - - Amino acid permease
CFHHBMID_01379 1.5e-108 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
CFHHBMID_01380 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
CFHHBMID_01381 2.71e-95 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
CFHHBMID_01382 2.12e-271 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
CFHHBMID_01383 3.8e-125 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
CFHHBMID_01384 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
CFHHBMID_01387 2.29e-200 yfmL - - L - - - DEAD DEAH box helicase
CFHHBMID_01388 1.78e-159 mocA - - S - - - Oxidoreductase
CFHHBMID_01389 2.63e-31 - - - S - - - Domain of unknown function (DUF4828)
CFHHBMID_01390 3.08e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CFHHBMID_01391 9.28e-42 - - - K - - - GNAT family
CFHHBMID_01392 1.96e-54 - - - - - - - -
CFHHBMID_01394 8.98e-229 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
CFHHBMID_01395 6.89e-118 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
CFHHBMID_01396 1.46e-147 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFHHBMID_01397 5.56e-124 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
CFHHBMID_01398 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
CFHHBMID_01399 3e-46 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
CFHHBMID_01400 1.56e-254 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
CFHHBMID_01401 1.37e-96 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CFHHBMID_01402 2.58e-77 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
CFHHBMID_01403 8.09e-82 - - - S - - - ECF transporter, substrate-specific component
CFHHBMID_01404 4.14e-16 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
CFHHBMID_01405 2.63e-83 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
CFHHBMID_01406 8.41e-148 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
CFHHBMID_01407 5.3e-102 yfiK - - K ko:K02479 - ko00000,ko02022 Bacterial regulatory proteins, luxR family
CFHHBMID_01408 3.34e-122 baeS - - T - - - Histidine kinase
CFHHBMID_01409 7.63e-102 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
CFHHBMID_01410 1.36e-193 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
CFHHBMID_01411 6.87e-153 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
CFHHBMID_01412 1.15e-187 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
CFHHBMID_01413 1.61e-67 - - - S - - - Domain of unknown function (DUF956)
CFHHBMID_01414 2.92e-314 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
CFHHBMID_01415 7.97e-90 mleR - - K - - - LysR family
CFHHBMID_01416 3.65e-74 napB - - K - - - transcriptional
CFHHBMID_01417 3.34e-52 - - - K - - - Bacterial regulatory proteins, tetR family
CFHHBMID_01418 1.62e-78 usp2 - - T - - - Belongs to the universal stress protein A family
CFHHBMID_01419 3.05e-59 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
CFHHBMID_01421 1.05e-05 - - - L ko:K07483 - ko00000 transposase activity
CFHHBMID_01423 6.18e-130 ypuA - - S - - - Protein of unknown function (DUF1002)
CFHHBMID_01424 6.72e-79 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
CFHHBMID_01425 2.67e-204 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFHHBMID_01426 2.35e-39 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
CFHHBMID_01427 3.63e-267 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
CFHHBMID_01428 1.19e-250 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
CFHHBMID_01429 4.35e-301 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CFHHBMID_01430 4.82e-20 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
CFHHBMID_01431 2.04e-181 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
CFHHBMID_01432 3.87e-14 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CFHHBMID_01433 6e-76 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CFHHBMID_01434 7.38e-123 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFHHBMID_01435 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
CFHHBMID_01436 1.25e-92 ywlG - - S - - - Belongs to the UPF0340 family
CFHHBMID_01437 2.67e-24 - - - S - - - transferase activity, transferring acyl groups
CFHHBMID_01438 2.13e-18 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
CFHHBMID_01439 3.98e-66 - - - K - - - Cro/C1-type HTH DNA-binding domain
CFHHBMID_01440 4.88e-205 spoVK - - O ko:K06413 - ko00000 PFAM ATPase family associated with various cellular activities (AAA)
CFHHBMID_01441 5.12e-92 - - - S - - - Domain of unknown function (DUF3841)
CFHHBMID_01442 4.08e-73 - - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
CFHHBMID_01443 4.34e-132 - - - S - - - Domain of unknown function (DUF4343)
CFHHBMID_01444 0.0 - - - L - - - helicase activity
CFHHBMID_01445 2.25e-265 - - - K - - - DNA binding
CFHHBMID_01446 0.0 res 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
CFHHBMID_01447 2e-285 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
CFHHBMID_01448 3.61e-296 - - - S - - - Protein of unknown function DUF262
CFHHBMID_01449 4.1e-19 - - - S - - - FRG
CFHHBMID_01451 1.5e-147 - - - L - - - DNA restriction-modification system
CFHHBMID_01453 7.3e-25 - - - K - - - Cro/C1-type HTH DNA-binding domain
CFHHBMID_01454 6.8e-145 - - - L - - - DEAD-like helicases superfamily
CFHHBMID_01458 7.69e-14 - - - - - - - -
CFHHBMID_01459 1.01e-172 - - - L - - - Protein of unknown function (DUF2800)
CFHHBMID_01460 1.21e-86 - - - S - - - Protein of unknown function (DUF2815)
CFHHBMID_01461 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase
CFHHBMID_01462 8.74e-98 rha - - K - - - phage regulatory protein, rha family
CFHHBMID_01463 5.23e-42 - - - S - - - Psort location Cytoplasmic, score
CFHHBMID_01464 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
CFHHBMID_01465 1.84e-256 - - - L - - - SNF2 family N-terminal domain
CFHHBMID_01466 2.77e-74 - - - - - - - -
CFHHBMID_01467 9.22e-110 - - - - - - - -
CFHHBMID_01468 5.87e-253 - - - KL - - - DNA methylase
CFHHBMID_01469 8.04e-55 - - - S - - - Psort location Cytoplasmic, score
CFHHBMID_01470 3.61e-25 - - - S - - - Domain of unknown function (DUF5049)
CFHHBMID_01471 0.0 - - - S - - - overlaps another CDS with the same product name
CFHHBMID_01472 2.97e-260 - - - S - - - Phage portal protein
CFHHBMID_01473 2.71e-121 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
CFHHBMID_01474 3.59e-204 - - - S - - - Phage capsid family
CFHHBMID_01475 1.94e-39 - - - S - - - Phage gp6-like head-tail connector protein
CFHHBMID_01476 7.97e-16 - - - S - - - head-tail adaptor
CFHHBMID_01477 2.41e-109 - - - M - - - hydrolase, family 25
CFHHBMID_01479 9.49e-151 - - - L ko:K06400 - ko00000 Resolvase, N terminal domain
CFHHBMID_01481 6.53e-152 - - - L - - - Recombinase
CFHHBMID_01483 8.84e-183 - - - L ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
CFHHBMID_01484 3.21e-270 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFHHBMID_01485 5.09e-183 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
CFHHBMID_01486 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFHHBMID_01487 7.24e-295 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CFHHBMID_01488 1.34e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFHHBMID_01489 6.9e-205 camS - - S - - - sex pheromone
CFHHBMID_01490 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFHHBMID_01491 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
CFHHBMID_01492 2.01e-183 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CFHHBMID_01494 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
CFHHBMID_01495 2.4e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFHHBMID_01496 1.13e-167 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFHHBMID_01497 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFHHBMID_01498 3.54e-100 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
CFHHBMID_01499 4.72e-116 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CFHHBMID_01500 1.23e-62 yabR - - J ko:K07571 - ko00000 RNA binding
CFHHBMID_01501 1.49e-28 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
CFHHBMID_01502 1.1e-42 yabO - - J - - - S4 domain protein
CFHHBMID_01503 1.32e-172 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
CFHHBMID_01504 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFHHBMID_01505 1.45e-95 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CFHHBMID_01506 8.16e-202 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
CFHHBMID_01507 1.08e-26 - - - V ko:K07448,ko:K07449 - ko00000,ko02048 Restriction endonuclease
CFHHBMID_01508 1.55e-110 - - - S - - - (CBS) domain
CFHHBMID_01509 4.44e-180 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFHHBMID_01510 8.24e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFHHBMID_01511 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
CFHHBMID_01512 8.18e-73 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
CFHHBMID_01513 1.27e-131 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
CFHHBMID_01514 7.16e-143 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CFHHBMID_01515 8e-189 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFHHBMID_01517 8.4e-66 - - - M - - - LysM domain protein
CFHHBMID_01518 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
CFHHBMID_01519 3.7e-110 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CFHHBMID_01520 1.05e-41 - - - K - - - transcriptional regulator (TetR family)
CFHHBMID_01521 3.06e-137 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
CFHHBMID_01522 2.21e-111 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_01523 5.1e-86 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
CFHHBMID_01524 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
CFHHBMID_01525 4.63e-306 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
CFHHBMID_01528 2.29e-79 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
CFHHBMID_01529 1.04e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFHHBMID_01530 3.6e-159 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CFHHBMID_01531 1.08e-138 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFHHBMID_01532 3.56e-139 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFHHBMID_01533 3.94e-128 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFHHBMID_01534 4.47e-71 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
CFHHBMID_01535 1.93e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFHHBMID_01536 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFHHBMID_01537 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFHHBMID_01538 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
CFHHBMID_01539 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFHHBMID_01540 8.94e-143 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CFHHBMID_01541 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CFHHBMID_01542 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
CFHHBMID_01543 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
CFHHBMID_01544 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFHHBMID_01545 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFHHBMID_01546 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFHHBMID_01547 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFHHBMID_01548 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFHHBMID_01549 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFHHBMID_01550 3.84e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFHHBMID_01551 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFHHBMID_01552 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFHHBMID_01553 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
CFHHBMID_01554 8.95e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFHHBMID_01555 1.62e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFHHBMID_01556 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFHHBMID_01557 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFHHBMID_01558 4.58e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFHHBMID_01559 1.34e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CFHHBMID_01560 6.55e-130 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
CFHHBMID_01561 2.82e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFHHBMID_01562 3.24e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
CFHHBMID_01563 3.13e-213 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFHHBMID_01564 1.07e-100 - - - K - - - rpiR family
CFHHBMID_01565 2.85e-69 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
CFHHBMID_01566 6.82e-187 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
CFHHBMID_01567 2.79e-14 - - - K - - - Acetyltransferase (GNAT) domain
CFHHBMID_01568 5.79e-240 steT - - E ko:K03294 - ko00000 amino acid
CFHHBMID_01569 5.39e-104 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CFHHBMID_01570 4.89e-111 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CFHHBMID_01571 9.76e-126 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CFHHBMID_01572 2.45e-132 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_01573 3.89e-17 - - - - - - - -
CFHHBMID_01574 3e-121 - - - - - - - -
CFHHBMID_01575 1.03e-16 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
CFHHBMID_01576 1e-68 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
CFHHBMID_01577 1.24e-268 yhdG - - E ko:K03294 - ko00000 Amino Acid
CFHHBMID_01578 8.41e-317 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CFHHBMID_01579 0.0 - - - L - - - Helicase C-terminal domain protein
CFHHBMID_01580 1.25e-101 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
CFHHBMID_01581 6.84e-232 yhdP - - S - - - Transporter associated domain
CFHHBMID_01582 2.76e-33 - - - - - - - -
CFHHBMID_01583 2.98e-100 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
CFHHBMID_01584 3.71e-161 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
CFHHBMID_01585 2.28e-125 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
CFHHBMID_01586 9.08e-91 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFHHBMID_01587 6.88e-200 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
CFHHBMID_01588 2.8e-174 - - - V - - - MatE
CFHHBMID_01589 2.08e-58 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFHHBMID_01590 1.36e-111 - - - S - - - Alpha beta hydrolase
CFHHBMID_01591 7.48e-122 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CFHHBMID_01592 5.23e-219 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFHHBMID_01593 1.24e-137 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
CFHHBMID_01594 6.37e-131 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
CFHHBMID_01595 7.29e-46 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
CFHHBMID_01596 1.09e-68 ccl - - S - - - QueT transporter
CFHHBMID_01598 1.88e-83 - - - S - - - Uncharacterised protein, DegV family COG1307
CFHHBMID_01599 2.37e-28 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFHHBMID_01600 2.19e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFHHBMID_01601 7.86e-46 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
CFHHBMID_01602 2.97e-110 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
CFHHBMID_01603 8.1e-157 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
CFHHBMID_01604 1.97e-64 - - - S - - - Threonine/Serine exporter, ThrE
CFHHBMID_01605 9.59e-104 - - - S - - - Putative threonine/serine exporter
CFHHBMID_01606 1.37e-37 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
CFHHBMID_01607 1.77e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
CFHHBMID_01608 1.01e-117 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
CFHHBMID_01609 1.23e-27 - - - - - - - -
CFHHBMID_01610 1.84e-74 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
CFHHBMID_01611 4.2e-23 - - - - - - - -
CFHHBMID_01612 1.39e-80 - - - I - - - alpha/beta hydrolase fold
CFHHBMID_01613 2.61e-52 - - - S - - - branched-chain amino acid
CFHHBMID_01614 1.78e-132 - - - E - - - AzlC protein
CFHHBMID_01615 1.81e-24 - - - - - - - -
CFHHBMID_01616 2.53e-163 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
CFHHBMID_01617 1.09e-150 yhgE - - V ko:K01421 - ko00000 domain protein
CFHHBMID_01622 2.63e-08 - - - S - - - Mor transcription activator family
CFHHBMID_01625 5.77e-74 - - - K - - - WYL domain
CFHHBMID_01626 3.53e-158 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFHHBMID_01627 5.45e-218 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
CFHHBMID_01628 2.26e-148 ydbI - - K - - - AI-2E family transporter
CFHHBMID_01629 2.95e-76 - - - EG - - - EamA-like transporter family
CFHHBMID_01630 4.32e-96 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
CFHHBMID_01631 2.79e-147 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
CFHHBMID_01632 8.99e-86 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
CFHHBMID_01633 1.27e-207 - - - C - - - Luciferase-like monooxygenase
CFHHBMID_01634 1.7e-55 hxlR - - K - - - Transcriptional regulator, HxlR family
CFHHBMID_01635 6.68e-219 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
CFHHBMID_01636 5.28e-131 gntR - - K - - - UbiC transcription regulator-associated domain protein
CFHHBMID_01637 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
CFHHBMID_01638 5.94e-107 pncA - - Q - - - isochorismatase
CFHHBMID_01639 1.61e-81 pgm1 - - G - - - phosphoglycerate mutase
CFHHBMID_01640 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFHHBMID_01641 1.13e-106 treR - - K ko:K03486 - ko00000,ko03000 UTRA
CFHHBMID_01642 3.38e-315 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
CFHHBMID_01643 6.82e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
CFHHBMID_01645 9.91e-225 XK27_08315 - - M - - - Sulfatase
CFHHBMID_01646 1.63e-199 caiT - - M ko:K03451 - ko00000 BCCT, betaine/carnitine/choline family transporter
CFHHBMID_01647 5.07e-108 - - - M - - - Nucleotidyl transferase
CFHHBMID_01648 3.03e-217 - - - M - - - Choline/ethanolamine kinase
CFHHBMID_01650 3.28e-65 - - - S - - - peptidoglycan catabolic process
CFHHBMID_01651 6.58e-113 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CFHHBMID_01652 5.11e-214 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
CFHHBMID_01653 1.41e-159 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CFHHBMID_01654 4.87e-222 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
CFHHBMID_01655 8.44e-98 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CFHHBMID_01656 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
CFHHBMID_01657 5.29e-78 - - - S - - - Psort location CytoplasmicMembrane, score
CFHHBMID_01658 6.99e-20 - - - S - - - Psort location CytoplasmicMembrane, score
CFHHBMID_01659 7.79e-44 - - - S - - - Bacterial membrane protein, YfhO
CFHHBMID_01660 2.41e-11 - - - S - - - Bacterial membrane protein, YfhO
CFHHBMID_01661 2.37e-72 - - - G - - - Peptidase_C39 like family
CFHHBMID_01662 1.52e-48 - - - S - - - Acyltransferase family
CFHHBMID_01665 4.55e-20 - - - - - - - -
CFHHBMID_01666 3.23e-60 cps3I - - G - - - Acyltransferase family
CFHHBMID_01667 3.68e-186 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
CFHHBMID_01668 4.37e-62 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
CFHHBMID_01669 2.93e-196 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
CFHHBMID_01670 8.69e-86 - - - S - - - NADPH-dependent FMN reductase
CFHHBMID_01671 3.74e-119 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CFHHBMID_01672 7.97e-206 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CFHHBMID_01673 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CFHHBMID_01674 5.37e-229 - - - S ko:K06915 - ko00000 cog cog0433
CFHHBMID_01675 3.76e-55 - - - S - - - SIR2-like domain
CFHHBMID_01676 1.53e-05 - - - S - - - SIR2-like domain
CFHHBMID_01677 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
CFHHBMID_01678 1.36e-171 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
CFHHBMID_01679 1.43e-56 - - - E - - - GDSL-like Lipase/Acylhydrolase
CFHHBMID_01680 3.91e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_01681 1.41e-240 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
CFHHBMID_01682 1.79e-268 potE - - E - - - Amino Acid
CFHHBMID_01683 2.92e-42 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
CFHHBMID_01684 1.4e-171 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
CFHHBMID_01685 1.08e-92 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
CFHHBMID_01686 2.36e-163 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFHHBMID_01687 2.12e-207 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFHHBMID_01688 4.73e-97 ung2 - - L - - - Uracil-DNA glycosylase
CFHHBMID_01689 3.61e-43 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
CFHHBMID_01690 1.03e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
CFHHBMID_01691 2.01e-27 - - - S - - - Protein of unknown function (DUF1700)
CFHHBMID_01692 9.13e-09 - - - S - - - Putative adhesin
CFHHBMID_01693 4.2e-23 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
CFHHBMID_01696 2.53e-91 - - - D - - - Peptidase family M23
CFHHBMID_01697 6.09e-237 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
CFHHBMID_01698 1.16e-246 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
CFHHBMID_01699 4.57e-121 - - - M - - - Core-2/I-Branching enzyme
CFHHBMID_01700 2.28e-122 - - - M - - - transferase activity, transferring glycosyl groups
CFHHBMID_01701 2.75e-86 - - - - - - - -
CFHHBMID_01702 4.17e-116 epsE2 - - M - - - Bacterial sugar transferase
CFHHBMID_01703 2.33e-162 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
CFHHBMID_01704 1.8e-143 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
CFHHBMID_01705 2.14e-117 ywqD - - D - - - Capsular exopolysaccharide family
CFHHBMID_01706 5.97e-95 epsB - - M - - - biosynthesis protein
CFHHBMID_01707 6.94e-43 - 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
CFHHBMID_01708 3.83e-125 - - - - - - - -
CFHHBMID_01709 2.83e-109 - - - M - - - Glycosyl transferases group 1
CFHHBMID_01710 2.23e-83 - - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
CFHHBMID_01712 2.1e-78 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
CFHHBMID_01713 3.08e-99 - - - M - - - Glycosyltransferase, group 2 family protein
CFHHBMID_01714 1.28e-143 cps2J - - S - - - Polysaccharide biosynthesis protein
CFHHBMID_01715 4.77e-42 - 2.3.1.79 - M ko:K00661 - ko00000,ko01000 Glycosyltransferase Family 4
CFHHBMID_01716 3.82e-135 - - - M - - - Glycosyl transferase 4-like domain
CFHHBMID_01718 3.83e-144 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
CFHHBMID_01719 6.65e-163 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CFHHBMID_01720 5.16e-213 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CFHHBMID_01721 2.26e-130 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CFHHBMID_01722 1.05e-178 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFHHBMID_01723 2.23e-124 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
CFHHBMID_01724 7.51e-117 - - - S - - - Bacterial membrane protein, YfhO
CFHHBMID_01725 4.57e-77 - - - S - - - Glycosyltransferase like family 2
CFHHBMID_01726 4.23e-150 cps3J - - M - - - Domain of unknown function (DUF4422)
CFHHBMID_01727 3.25e-48 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
CFHHBMID_01728 1.85e-114 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
CFHHBMID_01729 1.47e-81 - - - S - - - Haloacid dehalogenase-like hydrolase
CFHHBMID_01730 8.69e-192 - - - EGP - - - Major Facilitator
CFHHBMID_01732 9.43e-89 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
CFHHBMID_01733 9.23e-36 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
CFHHBMID_01734 1.08e-113 - - - S - - - NADPH-dependent FMN reductase
CFHHBMID_01735 9.97e-130 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
CFHHBMID_01736 1.98e-71 - - - S - - - ECF transporter, substrate-specific component
CFHHBMID_01737 6.99e-138 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
CFHHBMID_01738 1.13e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CFHHBMID_01739 2.2e-133 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
CFHHBMID_01740 6.49e-70 - - - V - - - Abi-like protein
CFHHBMID_01741 1.95e-46 - - - - - - - -
CFHHBMID_01742 2.53e-72 - - - S - - - Protein of unknown function (DUF1129)
CFHHBMID_01743 2.94e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CFHHBMID_01744 3.11e-33 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
CFHHBMID_01745 4.14e-138 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
CFHHBMID_01746 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
CFHHBMID_01747 8.74e-104 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
CFHHBMID_01748 3.62e-130 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
CFHHBMID_01749 4.08e-162 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
CFHHBMID_01750 2.99e-91 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
CFHHBMID_01751 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
CFHHBMID_01752 1.36e-78 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
CFHHBMID_01753 1.49e-94 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
CFHHBMID_01755 2.93e-82 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
CFHHBMID_01756 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
CFHHBMID_01757 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CFHHBMID_01758 1.43e-44 - - - - - - - -
CFHHBMID_01759 5.58e-180 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFHHBMID_01760 5.75e-197 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFHHBMID_01761 1.57e-123 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFHHBMID_01762 2.71e-197 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CFHHBMID_01763 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
CFHHBMID_01765 1.46e-119 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_01766 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
CFHHBMID_01767 1.47e-236 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
CFHHBMID_01768 4.68e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFHHBMID_01769 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
CFHHBMID_01770 6.4e-138 - - - P - - - Integral membrane protein TerC family
CFHHBMID_01771 3.75e-49 - - - K - - - Transcriptional regulator
CFHHBMID_01772 1.36e-121 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
CFHHBMID_01773 2.03e-128 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_01774 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CFHHBMID_01776 3.88e-60 - - - M - - - Glycosyl hydrolases family 25
CFHHBMID_01777 0.000156 - - - V - - - the current gene model (or a revised gene model) may contain a frame shift
CFHHBMID_01778 2.37e-235 noxE - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CFHHBMID_01779 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CFHHBMID_01780 2.7e-258 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
CFHHBMID_01781 1.03e-216 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
CFHHBMID_01782 1.78e-134 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
CFHHBMID_01783 1.7e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
CFHHBMID_01784 1.99e-88 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
CFHHBMID_01785 7.54e-193 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
CFHHBMID_01786 3.63e-145 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
CFHHBMID_01787 2.02e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
CFHHBMID_01788 2.37e-263 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
CFHHBMID_01790 8.07e-142 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
CFHHBMID_01791 9.17e-97 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
CFHHBMID_01792 2.88e-241 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
CFHHBMID_01793 1.89e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
CFHHBMID_01794 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
CFHHBMID_01795 3.49e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
CFHHBMID_01796 3.96e-76 - - - F - - - Nucleoside 2-deoxyribosyltransferase
CFHHBMID_01797 1.4e-96 azlC - - E - - - branched-chain amino acid
CFHHBMID_01798 1.49e-44 - - - S - - - Branched-chain amino acid transport protein (AzlD)
CFHHBMID_01799 2.21e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFHHBMID_01800 1.8e-69 jag - - S ko:K06346 - ko00000 R3H domain protein
CFHHBMID_01801 1.59e-68 - - - K - - - Transcriptional regulator C-terminal region
CFHHBMID_01802 2.5e-59 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
CFHHBMID_01803 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
CFHHBMID_01804 3.19e-139 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
CFHHBMID_01806 6.27e-85 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
CFHHBMID_01807 1.59e-60 hmpT - - S - - - ECF-type riboflavin transporter, S component
CFHHBMID_01808 3.95e-54 - - - K - - - Acetyltransferase GNAT Family
CFHHBMID_01809 4.54e-194 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
CFHHBMID_01810 6.69e-99 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
CFHHBMID_01811 1.42e-123 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_01812 1.11e-93 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFHHBMID_01813 5.75e-155 ytbE - - S - - - reductase
CFHHBMID_01814 1.22e-57 ytcD - - K - - - HxlR-like helix-turn-helix
CFHHBMID_01815 1.25e-130 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
CFHHBMID_01816 8.31e-87 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
CFHHBMID_01817 2.24e-95 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
CFHHBMID_01818 1.49e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
CFHHBMID_01819 5.58e-69 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CFHHBMID_01820 5.09e-60 - - - S - - - Short repeat of unknown function (DUF308)
CFHHBMID_01821 1.68e-23 - - - K - - - Transcriptional regulator C-terminal region
CFHHBMID_01822 5.32e-191 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
CFHHBMID_01824 7.07e-53 - - - K - - - LytTr DNA-binding domain
CFHHBMID_01825 2.35e-21 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
CFHHBMID_01826 9.37e-107 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
CFHHBMID_01827 2.75e-264 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CFHHBMID_01828 1.04e-20 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
CFHHBMID_01829 6.96e-197 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CFHHBMID_01830 6.06e-230 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CFHHBMID_01831 5.23e-217 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFHHBMID_01832 1.97e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFHHBMID_01833 1.87e-255 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
CFHHBMID_01834 7.19e-276 yifK - - E ko:K03293 - ko00000 Amino acid permease
CFHHBMID_01835 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFHHBMID_01836 1.09e-72 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
CFHHBMID_01837 3.17e-78 pgm3 - - G - - - phosphoglycerate mutase family
CFHHBMID_01838 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
CFHHBMID_01839 4.15e-26 - - - S - - - Cupredoxin-like domain
CFHHBMID_01840 6.06e-56 - - - S - - - Cupredoxin-like domain
CFHHBMID_01841 4.12e-189 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
CFHHBMID_01842 6.94e-177 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
CFHHBMID_01843 9.58e-40 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
CFHHBMID_01844 2.01e-146 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
CFHHBMID_01845 9.75e-30 - - - K - - - transcriptional regulator
CFHHBMID_01846 5.05e-44 - - - S - - - intracellular protease amidase
CFHHBMID_01847 3.32e-33 - - - S - - - intracellular protease amidase
CFHHBMID_01848 1.5e-169 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
CFHHBMID_01849 1.35e-101 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
CFHHBMID_01850 8.38e-178 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
CFHHBMID_01851 1.69e-254 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
CFHHBMID_01852 3.59e-149 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
CFHHBMID_01853 1.21e-29 - - - C - - - FMN_bind
CFHHBMID_01854 1.64e-16 - - - C - - - FMN_bind
CFHHBMID_01855 3.47e-201 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
CFHHBMID_01856 5.95e-249 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
CFHHBMID_01857 4.94e-94 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
CFHHBMID_01858 6.06e-165 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
CFHHBMID_01859 5.93e-128 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
CFHHBMID_01860 7.73e-105 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
CFHHBMID_01861 5.3e-12 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
CFHHBMID_01862 6.64e-77 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
CFHHBMID_01863 1.22e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CFHHBMID_01865 2.03e-291 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFHHBMID_01866 1.7e-82 - - - C - - - FMN binding
CFHHBMID_01867 1.24e-260 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
CFHHBMID_01868 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
CFHHBMID_01869 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
CFHHBMID_01874 4.13e-296 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFHHBMID_01875 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
CFHHBMID_01876 3.27e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
CFHHBMID_01877 8.99e-212 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CFHHBMID_01878 3.68e-151 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CFHHBMID_01879 1.26e-132 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CFHHBMID_01880 4.15e-202 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CFHHBMID_01881 4.56e-168 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
CFHHBMID_01882 9.74e-147 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CFHHBMID_01883 8.15e-138 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFHHBMID_01884 5.15e-75 - - - L - - - Probable transposase
CFHHBMID_01885 8.31e-133 - - - S ko:K07089 - ko00000 Predicted permease
CFHHBMID_01886 3.43e-80 - - - S - - - Sulphur transport
CFHHBMID_01887 9.43e-23 - - - O - - - Belongs to the sulfur carrier protein TusA family
CFHHBMID_01888 2.38e-148 - - - P - - - Rhodanese Homology Domain
CFHHBMID_01890 4.14e-292 prdA 1.21.4.1 - EJ ko:K10793 ko00330,map00330 ko00000,ko00001,ko01000 Glycine/sarcosine/betaine reductase component B subunits
CFHHBMID_01891 3.17e-34 - - - S - - - Psort location Cytoplasmic, score
CFHHBMID_01892 1.14e-84 prdB - - S - - - the current gene model (or a revised gene model) may contain a premature stop
CFHHBMID_01893 2.69e-42 - - - S - - - the current gene model (or a revised gene model) may contain a premature stop
CFHHBMID_01894 8.38e-92 - - - S - - - An automated process has identified a potential problem with this gene model
CFHHBMID_01895 6.97e-87 - - - EJ - - - Glycine/sarcosine/betaine reductase component B subunits
CFHHBMID_01896 2.59e-183 - 5.1.1.4 - E ko:K01777 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Proline racemase
CFHHBMID_01897 2.77e-123 - - - S - - - Sulfite exporter TauE/SafE
CFHHBMID_01898 8.84e-280 - - - E - - - amino acid
CFHHBMID_01899 2.48e-61 yedF - - O - - - Belongs to the sulfur carrier protein TusA family
CFHHBMID_01901 2.97e-167 selB - - J ko:K03833 - ko00000,ko03012 Elongation factor SelB, winged helix
CFHHBMID_01902 9.69e-138 - - - E - - - Serine hydroxymethyltransferase
CFHHBMID_01903 1.21e-142 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
CFHHBMID_01904 7.55e-38 - - - S - - - Iron-sulfur cluster assembly protein
CFHHBMID_01905 1.27e-234 - - - C - - - RnfC Barrel sandwich hybrid domain
CFHHBMID_01906 8.28e-125 selD 2.7.9.3 - E ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 Synthesizes selenophosphate from selenide and ATP
CFHHBMID_01907 1.31e-187 - - - S ko:K07112 - ko00000 Sulphur transport
CFHHBMID_01908 4.23e-38 - - - O - - - Belongs to the sulfur carrier protein TusA family
CFHHBMID_01909 2.84e-67 - - - S - - - COG NOG19168 non supervised orthologous group
CFHHBMID_01910 1.35e-230 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
CFHHBMID_01911 2.25e-64 - - - S - - - Membrane
CFHHBMID_01912 5.12e-94 - - - K - - - helix_turn_helix, arabinose operon control protein
CFHHBMID_01913 6.67e-239 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
CFHHBMID_01914 7.66e-274 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
CFHHBMID_01915 8.21e-53 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
CFHHBMID_01916 2.87e-276 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
CFHHBMID_01917 5.55e-142 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
CFHHBMID_01918 5.81e-240 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
CFHHBMID_01920 1.05e-212 potE2 - - E ko:K03294 - ko00000 amino acid
CFHHBMID_01921 1.17e-185 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
CFHHBMID_01922 1.29e-146 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFHHBMID_01923 4.39e-73 - - - K - - - Domain of unknown function (DUF1836)
CFHHBMID_01924 1.03e-103 yitS - - S - - - EDD domain protein, DegV family
CFHHBMID_01925 1.24e-47 - - - S - - - Enterocin A Immunity
CFHHBMID_01926 1.73e-49 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CFHHBMID_01927 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CFHHBMID_01928 1.23e-34 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
CFHHBMID_01929 3.22e-140 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
CFHHBMID_01930 9.83e-66 - - - C - - - Oxidoreductase NAD-binding domain
CFHHBMID_01931 1.97e-215 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
CFHHBMID_01932 4.41e-33 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFHHBMID_01933 3.22e-89 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CFHHBMID_01934 1.27e-180 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
CFHHBMID_01936 4.79e-39 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CFHHBMID_01937 2.63e-89 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
CFHHBMID_01938 1.75e-99 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
CFHHBMID_01939 1.54e-73 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFHHBMID_01940 1.7e-68 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
CFHHBMID_01941 1.04e-101 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
CFHHBMID_01942 4.69e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFHHBMID_01943 3.52e-100 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
CFHHBMID_01944 1.58e-35 - - - - - - - -
CFHHBMID_01945 1.14e-71 - - - L - - - Belongs to the 'phage' integrase family
CFHHBMID_01948 9.79e-35 - - - M - - - CHAP domain
CFHHBMID_01950 1.58e-235 - - - U - - - type IV secretory pathway VirB4
CFHHBMID_01953 9.85e-85 - - - - - - - -
CFHHBMID_01954 5.46e-265 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
CFHHBMID_01958 8.69e-182 - - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
CFHHBMID_01961 5.92e-201 topA2 5.99.1.2 - G ko:K03169 - ko00000,ko01000,ko03032 Topoisomerase IA
CFHHBMID_01962 4.97e-24 - - - L - - - Protein of unknown function (DUF3991)
CFHHBMID_01963 3.26e-74 - - - - - - - -
CFHHBMID_01965 1.89e-20 - - - L - - - PFAM Uncharacterised protein family UPF0236
CFHHBMID_01966 1.03e-07 - - - - - - - -
CFHHBMID_01967 4.92e-95 - - - DM - - - Glucan-binding protein C
CFHHBMID_01969 5.78e-135 - - - L - - - Belongs to the 'phage' integrase family
CFHHBMID_01970 3.4e-08 - - - S - - - Fic/DOC family
CFHHBMID_01972 1.39e-87 - - - D - - - nuclear chromosome segregation
CFHHBMID_01973 1.05e-08 - - - K - - - sequence-specific DNA binding
CFHHBMID_01974 5.74e-99 - - - S - - - Fic/DOC family
CFHHBMID_01977 1.02e-38 - - - L - - - four-way junction helicase activity
CFHHBMID_01981 5.19e-10 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
CFHHBMID_01988 3.54e-87 yciB - - M - - - ErfK YbiS YcfS YnhG
CFHHBMID_01989 1.14e-70 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CFHHBMID_01990 6.13e-286 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFHHBMID_01991 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CFHHBMID_01992 2.22e-131 pgm3 - - G - - - phosphoglycerate mutase
CFHHBMID_01993 3.97e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
CFHHBMID_01994 3.14e-62 - - - C - - - Flavodoxin
CFHHBMID_01995 4.35e-153 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
CFHHBMID_01996 1.04e-135 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
CFHHBMID_01997 2.65e-188 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFHHBMID_01998 5.23e-119 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CFHHBMID_01999 9.2e-168 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
CFHHBMID_02000 2.84e-107 - - - C - - - nitroreductase
CFHHBMID_02001 4.37e-106 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
CFHHBMID_02002 4.07e-137 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
CFHHBMID_02003 4.96e-213 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CFHHBMID_02004 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
CFHHBMID_02006 6.24e-192 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFHHBMID_02007 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CFHHBMID_02008 1.21e-161 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
CFHHBMID_02009 1.14e-67 - - - S - - - Protein of unknown function (DUF4256)
CFHHBMID_02016 4.44e-14 - - - S - - - Arc-like DNA binding domain
CFHHBMID_02017 7.27e-17 - - - K - - - Helix-turn-helix XRE-family like proteins
CFHHBMID_02018 3.76e-18 - - - - - - - -
CFHHBMID_02019 4.86e-141 rssA - - S - - - Phospholipase, patatin family
CFHHBMID_02026 5.17e-14 - 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Peptidase S24-like
CFHHBMID_02027 3.08e-11 - - - S - - - protein disulfide oxidoreductase activity
CFHHBMID_02028 1.32e-110 - - - S - - - Fic/DOC family
CFHHBMID_02032 2.08e-38 - - - - - - - -
CFHHBMID_02034 4.69e-94 XK27_05145 - - L - - - Belongs to the 'phage' integrase family
CFHHBMID_02035 1.01e-171 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
CFHHBMID_02036 5.31e-23 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
CFHHBMID_02037 2.4e-151 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CFHHBMID_02038 1.11e-85 - - - L - - - Transposase
CFHHBMID_02039 1.11e-174 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFHHBMID_02040 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
CFHHBMID_02041 1.91e-63 - - - S - - - VIT family
CFHHBMID_02042 3.74e-303 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
CFHHBMID_02043 1.15e-53 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
CFHHBMID_02044 9.81e-183 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFHHBMID_02045 1.74e-178 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
CFHHBMID_02046 5.23e-148 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
CFHHBMID_02047 6.35e-281 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
CFHHBMID_02048 6.14e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
CFHHBMID_02050 1.51e-42 - - - S - - - ABC-2 family transporter protein
CFHHBMID_02051 3.04e-92 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
CFHHBMID_02052 3.82e-128 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
CFHHBMID_02053 1.57e-57 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)