Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IMILKFDD_00001	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
IMILKFDD_00002	1.54e-137	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IMILKFDD_00003	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IMILKFDD_00004	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IMILKFDD_00005	1.1e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMILKFDD_00006	1.81e-201	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IMILKFDD_00007	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
IMILKFDD_00008	2.79e-192	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMILKFDD_00009	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMILKFDD_00010	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMILKFDD_00011	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IMILKFDD_00012	6.48e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IMILKFDD_00013	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMILKFDD_00014	1.35e-136	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
IMILKFDD_00015	6.63e-148	-	-	-	S	-	-	-	Glycosyl transferase family 2
IMILKFDD_00016	3.2e-81	-	-	-	D	-	-	-	peptidase
IMILKFDD_00017	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IMILKFDD_00018	4.6e-57	cps3F	-	-	-	-	-	-	-
IMILKFDD_00019	2.22e-108	-	-	-	S	-	-	-	Membrane
IMILKFDD_00020	0.0	-	-	-	E	-	-	-	Amino acid permease
IMILKFDD_00021	4.84e-291	cadA	-	-	P	-	-	-	P-type ATPase
IMILKFDD_00022	2.47e-146	degV	-	-	S	-	-	-	EDD domain protein, DegV family
IMILKFDD_00023	2.05e-189	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IMILKFDD_00024	1.68e-69	-	-	-	F	-	-	-	glutamine amidotransferase
IMILKFDD_00025	1.67e-35	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
IMILKFDD_00026	6.07e-186	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IMILKFDD_00027	5.98e-171	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IMILKFDD_00028	1.95e-102	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IMILKFDD_00029	2.75e-206	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
IMILKFDD_00030	7.09e-20	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IMILKFDD_00031	3.64e-285	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IMILKFDD_00032	8.44e-148	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IMILKFDD_00033	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
IMILKFDD_00034	3.86e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IMILKFDD_00035	6.7e-107	lysR5	-	-	K	-	-	-	LysR substrate binding domain
IMILKFDD_00036	1.51e-71	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
IMILKFDD_00037	2.9e-14	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMILKFDD_00038	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IMILKFDD_00039	7.88e-87	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IMILKFDD_00040	7.55e-308	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
IMILKFDD_00041	7.95e-263	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMILKFDD_00049	1.38e-165	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IMILKFDD_00050	5.35e-235	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IMILKFDD_00051	3.2e-198	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IMILKFDD_00052	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IMILKFDD_00053	4.06e-150	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IMILKFDD_00055	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IMILKFDD_00056	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IMILKFDD_00057	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMILKFDD_00058	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMILKFDD_00059	3.15e-29	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
IMILKFDD_00060	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMILKFDD_00061	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IMILKFDD_00062	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMILKFDD_00063	3.83e-116	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IMILKFDD_00064	1.11e-105	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IMILKFDD_00065	1.21e-145	vanR	-	-	K	-	-	-	response regulator
IMILKFDD_00066	3.05e-190	hpk31	-	-	T	-	-	-	Histidine kinase
IMILKFDD_00067	1.37e-111	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IMILKFDD_00068	1.37e-188	-	-	-	G	-	-	-	Transporter, major facilitator family protein
IMILKFDD_00069	1.28e-276	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IMILKFDD_00070	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_00071	3.9e-23	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IMILKFDD_00073	2.66e-279	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_00074	8.83e-316	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IMILKFDD_00075	1.29e-11	-	-	-	-	-	-	-	-
IMILKFDD_00076	1.41e-48	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
IMILKFDD_00077	1.2e-67	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
IMILKFDD_00078	3.28e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IMILKFDD_00079	2.51e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IMILKFDD_00081	0.0	-	-	-	L	-	-	-	DNA helicase
IMILKFDD_00082	2.75e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMILKFDD_00083	2.82e-217	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IMILKFDD_00084	1.06e-126	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IMILKFDD_00085	1.58e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMILKFDD_00086	1.48e-129	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IMILKFDD_00087	1.91e-40	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IMILKFDD_00088	3.74e-55	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
IMILKFDD_00089	5.23e-188	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IMILKFDD_00090	5.58e-163	-	-	-	-	-	-	-	-
IMILKFDD_00091	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMILKFDD_00092	1.8e-133	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IMILKFDD_00093	6.92e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IMILKFDD_00094	2.18e-168	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IMILKFDD_00095	1.9e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
IMILKFDD_00096	1.1e-114	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IMILKFDD_00097	5.51e-171	arcT	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
IMILKFDD_00098	5.91e-61	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IMILKFDD_00099	3.59e-148	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMILKFDD_00100	2.12e-193	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IMILKFDD_00102	6.47e-115	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IMILKFDD_00103	4.14e-43	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
IMILKFDD_00104	7.92e-31	-	-	-	-	-	-	-	-
IMILKFDD_00106	2.6e-93	-	-	-	-	-	-	-	-
IMILKFDD_00107	1.08e-12	-	-	-	-	-	-	-	-
IMILKFDD_00110	9.11e-51	-	-	-	K	-	-	-	Helix-turn-helix domain
IMILKFDD_00112	1.45e-23	-	-	-	-	-	-	-	-
IMILKFDD_00114	1.11e-32	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IMILKFDD_00117	9.47e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
IMILKFDD_00118	8.68e-56	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
IMILKFDD_00126	2.37e-45	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
IMILKFDD_00127	3.66e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
IMILKFDD_00128	1.62e-61	-	-	-	-	-	-	-	-
IMILKFDD_00132	1.78e-111	-	-	-	L	-	-	-	HNH nucleases
IMILKFDD_00133	1.05e-107	-	-	-	L	-	-	-	Phage terminase, small subunit
IMILKFDD_00134	0.0	-	-	-	S	-	-	-	Phage Terminase
IMILKFDD_00136	5.68e-245	-	-	-	S	-	-	-	Phage portal protein
IMILKFDD_00137	2.72e-148	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
IMILKFDD_00138	1.96e-245	-	-	-	S	-	-	-	Phage capsid family
IMILKFDD_00139	4.39e-29	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IMILKFDD_00140	2.49e-75	-	-	-	S	-	-	-	Phage head-tail joining protein
IMILKFDD_00141	1.11e-68	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IMILKFDD_00142	6.94e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
IMILKFDD_00143	4.34e-99	-	-	-	S	-	-	-	Phage tail tube protein
IMILKFDD_00144	9.54e-25	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
IMILKFDD_00146	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
IMILKFDD_00147	6.21e-100	-	-	-	S	-	-	-	Phage tail protein
IMILKFDD_00148	9.2e-152	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
IMILKFDD_00153	1.93e-253	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IMILKFDD_00154	1.86e-247	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IMILKFDD_00155	2.34e-188	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IMILKFDD_00156	5.48e-159	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMILKFDD_00157	8.86e-140	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IMILKFDD_00159	4.3e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IMILKFDD_00160	5.27e-53	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IMILKFDD_00161	1.37e-20	-	-	-	M	-	-	-	MucBP domain
IMILKFDD_00162	6.82e-235	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMILKFDD_00163	1.2e-66	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
IMILKFDD_00164	1.05e-174	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IMILKFDD_00165	5.98e-70	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IMILKFDD_00166	1.95e-257	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMILKFDD_00167	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMILKFDD_00168	1.76e-24	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMILKFDD_00169	5.54e-139	dkgB	-	-	S	-	-	-	reductase
IMILKFDD_00170	1.82e-33	-	-	-	-	-	-	-	-
IMILKFDD_00171	8.5e-13	-	-	-	F	-	-	-	Phosphorylase superfamily
IMILKFDD_00172	5.25e-42	-	-	-	F	-	-	-	Phosphorylase superfamily
IMILKFDD_00173	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IMILKFDD_00174	2.88e-23	-	-	-	S	-	-	-	Belongs to the UPF0173 family
IMILKFDD_00175	1.25e-42	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
IMILKFDD_00176	2.02e-123	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IMILKFDD_00177	1.94e-157	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IMILKFDD_00178	1.35e-109	-	-	-	S	-	-	-	overlaps another CDS with the same product name
IMILKFDD_00179	2.01e-59	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
IMILKFDD_00181	1.99e-25	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	PIF1-like helicase
IMILKFDD_00183	1.29e-79	-	-	-	-	-	-	-	-
IMILKFDD_00184	2.14e-132	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
IMILKFDD_00185	3.53e-111	-	-	-	S	-	-	-	hydrolase
IMILKFDD_00186	6.95e-261	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
IMILKFDD_00187	4.07e-109	-	-	-	F	-	-	-	glutamine amidotransferase
IMILKFDD_00188	1.8e-32	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IMILKFDD_00189	1.68e-54	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IMILKFDD_00190	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IMILKFDD_00193	4.21e-251	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMILKFDD_00194	5.54e-240	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IMILKFDD_00195	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IMILKFDD_00196	1.05e-77	-	-	-	-	-	-	-	-
IMILKFDD_00197	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
IMILKFDD_00199	2.41e-101	-	-	-	S	-	-	-	Cell surface protein
IMILKFDD_00201	1.01e-229	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IMILKFDD_00202	4.31e-55	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IMILKFDD_00203	4.79e-42	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IMILKFDD_00205	6.17e-77	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IMILKFDD_00206	1.05e-81	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
IMILKFDD_00207	5.71e-225	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IMILKFDD_00208	1.32e-282	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IMILKFDD_00209	2.12e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IMILKFDD_00210	1.53e-181	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMILKFDD_00212	5e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IMILKFDD_00213	7.46e-116	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
IMILKFDD_00214	6.62e-196	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
IMILKFDD_00215	5.16e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IMILKFDD_00216	4.12e-75	-	-	-	-	-	-	-	-
IMILKFDD_00217	1.91e-53	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IMILKFDD_00218	9.05e-30	-	-	-	S	-	-	-	Cytochrome B5
IMILKFDD_00220	3.19e-79	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IMILKFDD_00221	3.65e-241	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMILKFDD_00222	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IMILKFDD_00223	1.42e-135	yueF	-	-	S	-	-	-	AI-2E family transporter
IMILKFDD_00224	3.8e-201	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IMILKFDD_00225	9.84e-147	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IMILKFDD_00226	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IMILKFDD_00227	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
IMILKFDD_00228	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
IMILKFDD_00229	2.26e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IMILKFDD_00230	1.07e-225	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMILKFDD_00231	1.04e-206	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMILKFDD_00232	1.15e-250	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IMILKFDD_00233	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IMILKFDD_00234	6.64e-131	-	-	-	G	-	-	-	MucBP domain
IMILKFDD_00235	3.55e-31	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IMILKFDD_00236	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IMILKFDD_00237	1.5e-22	-	-	-	-	-	-	-	-
IMILKFDD_00238	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IMILKFDD_00239	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMILKFDD_00240	2.09e-202	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IMILKFDD_00241	3.2e-164	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IMILKFDD_00242	8.79e-166	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IMILKFDD_00243	1.41e-35	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
IMILKFDD_00244	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IMILKFDD_00245	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IMILKFDD_00259	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IMILKFDD_00260	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IMILKFDD_00261	5.31e-262	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IMILKFDD_00262	4.86e-82	-	-	-	C	-	-	-	FMN binding
IMILKFDD_00263	1.78e-273	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
IMILKFDD_00264	1.53e-61	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IMILKFDD_00265	1.95e-82	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IMILKFDD_00266	4.1e-287	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IMILKFDD_00267	1.01e-53	yjbH	-	-	Q	-	-	-	Thioredoxin
IMILKFDD_00268	3.06e-125	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IMILKFDD_00269	2.58e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IMILKFDD_00270	1.35e-154	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IMILKFDD_00271	7.48e-147	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IMILKFDD_00272	3.05e-147	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IMILKFDD_00273	2.26e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IMILKFDD_00274	1.21e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
IMILKFDD_00275	1.39e-100	-	-	-	S	-	-	-	VIT family
IMILKFDD_00276	2.71e-107	-	-	-	S	-	-	-	membrane
IMILKFDD_00277	3.9e-24	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IMILKFDD_00278	8.68e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IMILKFDD_00279	9.71e-47	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IMILKFDD_00280	3.43e-96	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMILKFDD_00282	2.23e-10	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IMILKFDD_00284	2.46e-87	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
IMILKFDD_00285	8.56e-39	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
IMILKFDD_00286	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IMILKFDD_00287	5.13e-202	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IMILKFDD_00288	4.81e-54	-	-	-	S	-	-	-	VanZ like family
IMILKFDD_00289	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IMILKFDD_00290	1.16e-129	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMILKFDD_00291	1.11e-152	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IMILKFDD_00292	7.88e-122	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IMILKFDD_00293	4.34e-36	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
IMILKFDD_00294	1.42e-17	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
IMILKFDD_00298	1.41e-123	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IMILKFDD_00299	1.22e-238	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IMILKFDD_00300	9.2e-73	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IMILKFDD_00301	3.71e-78	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IMILKFDD_00302	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IMILKFDD_00303	4.54e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IMILKFDD_00304	1.08e-117	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
IMILKFDD_00305	4.05e-119	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IMILKFDD_00306	2.55e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
IMILKFDD_00307	5.2e-225	-	-	-	S	-	-	-	Protein of unknown function DUF262
IMILKFDD_00309	1.26e-48	-	-	-	-	-	-	-	-
IMILKFDD_00310	9.26e-87	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IMILKFDD_00311	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IMILKFDD_00312	2.12e-129	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMILKFDD_00313	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMILKFDD_00314	1.21e-130	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IMILKFDD_00315	6.31e-125	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IMILKFDD_00316	4.97e-248	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IMILKFDD_00317	4.05e-61	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IMILKFDD_00318	4.61e-84	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IMILKFDD_00319	2.06e-274	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IMILKFDD_00320	3.3e-160	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IMILKFDD_00321	9.99e-129	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
IMILKFDD_00322	7.35e-140	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IMILKFDD_00323	6.3e-290	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IMILKFDD_00324	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IMILKFDD_00325	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IMILKFDD_00326	1.05e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
IMILKFDD_00327	3.09e-59	ykuL	-	-	S	-	-	-	CBS domain
IMILKFDD_00328	1.39e-91	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IMILKFDD_00329	4.06e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IMILKFDD_00330	9.23e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IMILKFDD_00333	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IMILKFDD_00334	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IMILKFDD_00335	6.56e-163	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IMILKFDD_00336	1.22e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IMILKFDD_00338	3.15e-69	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
IMILKFDD_00339	1.16e-121	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_00340	2.82e-85	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IMILKFDD_00341	3.39e-125	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
IMILKFDD_00342	8.2e-131	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IMILKFDD_00344	2.95e-59	ytpP	-	-	CO	-	-	-	Thioredoxin
IMILKFDD_00345	2.48e-97	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IMILKFDD_00346	5.61e-297	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IMILKFDD_00347	1.24e-282	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IMILKFDD_00348	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
IMILKFDD_00349	1.25e-87	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IMILKFDD_00350	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMILKFDD_00351	5.99e-137	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IMILKFDD_00352	5.32e-63	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IMILKFDD_00353	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMILKFDD_00354	2.46e-95	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
IMILKFDD_00355	3.28e-136	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IMILKFDD_00356	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMILKFDD_00357	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMILKFDD_00358	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IMILKFDD_00359	5.01e-69	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMILKFDD_00360	2.34e-91	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
IMILKFDD_00361	2.94e-229	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IMILKFDD_00362	1.36e-40	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
IMILKFDD_00363	4.98e-99	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMILKFDD_00364	3.44e-91	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IMILKFDD_00365	2.79e-65	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IMILKFDD_00366	2.64e-103	-	-	-	H	-	-	-	Nodulation protein S (NodS)
IMILKFDD_00367	3.25e-153	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IMILKFDD_00368	1.58e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IMILKFDD_00369	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IMILKFDD_00370	5.76e-113	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IMILKFDD_00371	4.86e-120	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IMILKFDD_00372	6.9e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
IMILKFDD_00373	4.91e-172	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IMILKFDD_00374	7.31e-164	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMILKFDD_00375	1.82e-49	-	-	-	-	-	-	-	-
IMILKFDD_00376	1.91e-119	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
IMILKFDD_00377	9.37e-76	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMILKFDD_00378	1.81e-199	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IMILKFDD_00379	2.95e-284	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMILKFDD_00380	4.69e-131	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IMILKFDD_00382	1.46e-141	csrR	-	-	K	-	-	-	response regulator
IMILKFDD_00383	2.06e-216	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IMILKFDD_00384	1.19e-151	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IMILKFDD_00385	5.31e-23	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IMILKFDD_00386	1.36e-169	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IMILKFDD_00387	1.68e-118	XK27_05145	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IMILKFDD_00388	1.68e-17	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
IMILKFDD_00390	2.09e-47	-	-	-	E	-	-	-	Zn peptidase
IMILKFDD_00391	3.15e-59	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IMILKFDD_00393	1.36e-18	-	-	-	-	-	-	-	-
IMILKFDD_00394	2.8e-41	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IMILKFDD_00395	2.51e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IMILKFDD_00396	7.03e-58	-	-	-	S	-	-	-	DNA binding
IMILKFDD_00403	3.01e-143	-	-	-	-	-	-	-	-
IMILKFDD_00404	1.14e-147	-	-	-	-	-	-	-	-
IMILKFDD_00405	1.45e-48	-	-	-	S	-	-	-	Protein conserved in bacteria
IMILKFDD_00406	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMILKFDD_00407	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IMILKFDD_00408	1.45e-46	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMILKFDD_00409	3.85e-132	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMILKFDD_00410	3.49e-183	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IMILKFDD_00411	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IMILKFDD_00412	4.39e-104	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IMILKFDD_00413	6.31e-154	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IMILKFDD_00414	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IMILKFDD_00415	1.17e-235	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IMILKFDD_00416	1.83e-106	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMILKFDD_00417	7.41e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
IMILKFDD_00418	3.98e-36	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IMILKFDD_00419	3.24e-118	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IMILKFDD_00420	1.25e-57	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
IMILKFDD_00421	2.76e-87	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
IMILKFDD_00423	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IMILKFDD_00424	5.52e-51	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMILKFDD_00425	1.29e-89	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
IMILKFDD_00426	2.47e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IMILKFDD_00427	8.22e-203	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IMILKFDD_00428	6.86e-59	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IMILKFDD_00429	6.17e-24	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
IMILKFDD_00430	2.47e-140	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMILKFDD_00431	1.56e-257	ynbB	-	-	P	-	-	-	aluminum resistance
IMILKFDD_00432	1.84e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
IMILKFDD_00433	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IMILKFDD_00435	6.13e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMILKFDD_00436	8.28e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
IMILKFDD_00437	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IMILKFDD_00438	8.26e-105	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IMILKFDD_00439	1.16e-133	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMILKFDD_00440	6.42e-131	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IMILKFDD_00441	2.92e-195	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IMILKFDD_00442	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IMILKFDD_00443	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMILKFDD_00444	1.16e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IMILKFDD_00445	1.25e-216	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IMILKFDD_00446	3.32e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IMILKFDD_00447	4.38e-35	ylxQ	-	-	J	-	-	-	ribosomal protein
IMILKFDD_00448	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMILKFDD_00449	3.67e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMILKFDD_00450	1.65e-151	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMILKFDD_00451	5.22e-120	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IMILKFDD_00452	1.51e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IMILKFDD_00453	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMILKFDD_00454	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IMILKFDD_00455	5.74e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IMILKFDD_00456	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IMILKFDD_00458	7.05e-257	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IMILKFDD_00459	1.5e-152	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_00460	1.83e-41	-	-	-	-	-	-	-	-
IMILKFDD_00461	2.17e-140	ampC	-	-	V	-	-	-	Beta-lactamase
IMILKFDD_00462	9.59e-104	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
IMILKFDD_00463	2.99e-64	-	-	-	L	-	-	-	Helix-turn-helix domain
IMILKFDD_00464	6.58e-141	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
IMILKFDD_00465	2.09e-277	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
IMILKFDD_00466	1.19e-111	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IMILKFDD_00467	4.22e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMILKFDD_00468	3.04e-113	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IMILKFDD_00469	6.66e-172	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IMILKFDD_00470	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMILKFDD_00471	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IMILKFDD_00472	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMILKFDD_00473	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMILKFDD_00474	1.99e-74	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMILKFDD_00475	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMILKFDD_00476	3.29e-181	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMILKFDD_00477	8.04e-313	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMILKFDD_00478	6.22e-70	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IMILKFDD_00479	3.25e-307	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IMILKFDD_00480	5.01e-22	yneR	-	-	-	-	-	-	-
IMILKFDD_00481	1.45e-289	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMILKFDD_00482	1.25e-282	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IMILKFDD_00483	2.34e-136	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IMILKFDD_00484	1.29e-192	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IMILKFDD_00485	1.25e-06	-	-	-	K	-	-	-	YsiA-like protein, C-terminal region
IMILKFDD_00486	6.3e-141	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IMILKFDD_00487	1.86e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
IMILKFDD_00488	3.11e-90	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IMILKFDD_00489	9.44e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
IMILKFDD_00490	9.33e-249	pepF	-	-	E	-	-	-	Oligopeptidase F
IMILKFDD_00491	1.85e-06	pepF	-	-	E	-	-	-	Peptidase family M3
IMILKFDD_00492	1.22e-56	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
IMILKFDD_00493	7.01e-225	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IMILKFDD_00494	1.88e-174	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
IMILKFDD_00495	1.02e-80	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IMILKFDD_00496	3.06e-32	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IMILKFDD_00498	1.84e-217	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IMILKFDD_00499	2.33e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IMILKFDD_00500	3.07e-269	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_00501	6.42e-286	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
IMILKFDD_00502	1e-135	yxeH	-	-	S	-	-	-	hydrolase
IMILKFDD_00503	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IMILKFDD_00504	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IMILKFDD_00505	7.57e-126	yycH	-	-	S	-	-	-	YycH protein
IMILKFDD_00506	3.35e-100	yycI	-	-	S	-	-	-	YycH protein
IMILKFDD_00507	1.37e-40	-	-	-	S	-	-	-	YjbR
IMILKFDD_00508	1.46e-147	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IMILKFDD_00509	6.16e-187	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IMILKFDD_00510	7.88e-94	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IMILKFDD_00511	2.65e-52	-	-	-	GM	-	-	-	NAD(P)H-binding
IMILKFDD_00512	7.38e-34	-	-	-	K	-	-	-	MarR family transcriptional regulator
IMILKFDD_00513	3.84e-112	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IMILKFDD_00514	6.03e-19	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
IMILKFDD_00517	5.04e-257	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
IMILKFDD_00518	1.11e-36	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
IMILKFDD_00519	6.79e-87	-	-	-	L	-	-	-	HTH-like domain
IMILKFDD_00520	7.35e-07	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
IMILKFDD_00521	8.37e-18	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
IMILKFDD_00522	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IMILKFDD_00523	1.46e-260	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMILKFDD_00524	2.82e-214	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IMILKFDD_00525	3.25e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IMILKFDD_00526	6.63e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IMILKFDD_00527	2.21e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IMILKFDD_00528	9.86e-36	spxA	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IMILKFDD_00529	5.39e-120	-	-	-	M	-	-	-	Phosphotransferase enzyme family
IMILKFDD_00530	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IMILKFDD_00531	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IMILKFDD_00532	2.16e-152	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMILKFDD_00533	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMILKFDD_00534	3.13e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMILKFDD_00535	8.79e-193	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMILKFDD_00536	3.18e-115	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IMILKFDD_00537	6.52e-237	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IMILKFDD_00538	6.87e-146	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IMILKFDD_00539	4.31e-73	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IMILKFDD_00540	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IMILKFDD_00541	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IMILKFDD_00542	1.21e-302	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IMILKFDD_00543	3.32e-307	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMILKFDD_00544	4.4e-180	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IMILKFDD_00545	9.72e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMILKFDD_00546	4.17e-129	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IMILKFDD_00547	8.24e-296	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IMILKFDD_00548	1.3e-186	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IMILKFDD_00549	6.15e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IMILKFDD_00550	1.82e-262	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMILKFDD_00551	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IMILKFDD_00552	1.99e-37	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IMILKFDD_00553	3.22e-74	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMILKFDD_00554	2.25e-144	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IMILKFDD_00555	2.19e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IMILKFDD_00556	5.87e-249	-	-	-	E	ko:K03294	-	ko00000	amino acid
IMILKFDD_00557	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IMILKFDD_00558	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IMILKFDD_00559	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMILKFDD_00560	1.26e-145	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMILKFDD_00561	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMILKFDD_00562	0.000361	-	-	-	S	-	-	-	Tetratricopeptide repeat
IMILKFDD_00563	9.71e-274	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMILKFDD_00564	4.78e-246	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IMILKFDD_00565	7.41e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMILKFDD_00566	3.87e-315	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IMILKFDD_00567	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMILKFDD_00568	3.47e-29	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IMILKFDD_00569	3.51e-33	-	-	-	-	-	-	-	-
IMILKFDD_00570	1.36e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IMILKFDD_00571	3.48e-21	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
IMILKFDD_00572	3.42e-31	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IMILKFDD_00573	4.29e-96	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
IMILKFDD_00574	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IMILKFDD_00575	1.09e-187	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IMILKFDD_00576	7.81e-147	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
IMILKFDD_00577	2.92e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IMILKFDD_00578	2.48e-125	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IMILKFDD_00579	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IMILKFDD_00580	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
IMILKFDD_00581	1.5e-95	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IMILKFDD_00582	3.35e-65	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMILKFDD_00583	1.48e-166	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IMILKFDD_00584	1.22e-122	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IMILKFDD_00585	1.85e-40	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMILKFDD_00586	4.77e-132	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMILKFDD_00587	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMILKFDD_00588	1.76e-282	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IMILKFDD_00589	3.28e-173	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IMILKFDD_00590	6.95e-96	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMILKFDD_00591	1.4e-291	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IMILKFDD_00592	1.86e-200	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IMILKFDD_00593	3.92e-138	-	-	-	S	-	-	-	Acyltransferase family
IMILKFDD_00594	1.59e-241	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMILKFDD_00595	2.58e-156	-	-	-	K	-	-	-	LysR substrate binding domain
IMILKFDD_00597	6.94e-28	-	-	-	-	-	-	-	-
IMILKFDD_00598	1.03e-65	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IMILKFDD_00599	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IMILKFDD_00600	9.6e-61	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IMILKFDD_00601	1.71e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IMILKFDD_00602	4.97e-186	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IMILKFDD_00603	9.67e-132	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IMILKFDD_00604	3.76e-143	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IMILKFDD_00605	2.3e-172	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IMILKFDD_00606	1.78e-156	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IMILKFDD_00607	2.23e-120	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
IMILKFDD_00608	1.87e-271	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IMILKFDD_00609	1.55e-45	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IMILKFDD_00610	2.23e-181	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IMILKFDD_00611	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IMILKFDD_00612	2.93e-71	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
IMILKFDD_00613	4.21e-106	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMILKFDD_00614	6.01e-100	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMILKFDD_00615	3.06e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMILKFDD_00616	5.9e-117	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IMILKFDD_00617	1.49e-107	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
IMILKFDD_00618	3.08e-126	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IMILKFDD_00621	2.08e-148	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IMILKFDD_00622	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IMILKFDD_00623	1.87e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
IMILKFDD_00625	1.91e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IMILKFDD_00626	1.89e-142	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMILKFDD_00627	1.85e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IMILKFDD_00628	9.61e-166	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IMILKFDD_00629	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_00630	1.36e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IMILKFDD_00631	6.15e-73	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMILKFDD_00633	2.14e-99	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IMILKFDD_00634	7.98e-69	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
IMILKFDD_00635	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IMILKFDD_00636	2.54e-170	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IMILKFDD_00637	3.91e-122	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMILKFDD_00638	3.94e-106	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IMILKFDD_00639	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMILKFDD_00640	4.95e-265	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IMILKFDD_00641	1.91e-256	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
IMILKFDD_00642	5.8e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IMILKFDD_00643	1.94e-166	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IMILKFDD_00644	2.5e-256	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
IMILKFDD_00645	1.68e-42	-	-	-	S	-	-	-	Pfam:DUF2276
IMILKFDD_00646	6.31e-252	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
IMILKFDD_00647	6.4e-43	-	-	-	L	ko:K19138	-	ko00000,ko02048	Pfam:DUF310
IMILKFDD_00648	6.65e-89	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
IMILKFDD_00649	2.97e-82	-	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
IMILKFDD_00650	7.54e-87	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	RAMP superfamily
IMILKFDD_00651	6.72e-111	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IMILKFDD_00652	2.56e-42	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IMILKFDD_00653	8.74e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IMILKFDD_00654	1.45e-129	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
IMILKFDD_00655	3.68e-55	-	-	-	S	-	-	-	repeat protein
IMILKFDD_00656	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IMILKFDD_00657	3e-69	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
IMILKFDD_00660	1.13e-144	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IMILKFDD_00661	3.5e-20	-	-	-	-	-	-	-	-
IMILKFDD_00665	5.53e-18	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
IMILKFDD_00667	5.26e-34	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IMILKFDD_00668	3.01e-17	-	-	-	-	-	-	-	-
IMILKFDD_00669	2.97e-20	-	-	-	K	-	-	-	Transcriptional regulator
IMILKFDD_00671	7.65e-25	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
IMILKFDD_00677	2.18e-23	-	-	-	S	-	-	-	HNH endonuclease
IMILKFDD_00679	2.48e-139	-	-	-	L	-	-	-	snf2 family
IMILKFDD_00683	1.35e-153	-	-	-	L	-	-	-	AAA domain
IMILKFDD_00684	2.02e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
IMILKFDD_00685	6.07e-219	-	-	-	L	-	-	-	DNA polymerase elongation subunit (Family B)
IMILKFDD_00686	1.82e-192	-	-	-	L	ko:K06919	-	ko00000	Phage plasmid primase, P4 family
IMILKFDD_00695	4.01e-06	-	-	-	-	-	-	-	-
IMILKFDD_00702	4.44e-24	-	-	-	L	-	-	-	HNH endonuclease
IMILKFDD_00703	4.41e-41	-	-	-	L	-	-	-	Phage terminase, small subunit
IMILKFDD_00704	3.25e-269	-	-	-	S	-	-	-	Terminase
IMILKFDD_00705	1.49e-126	-	-	-	S	-	-	-	Phage portal protein, HK97 family
IMILKFDD_00706	3.15e-89	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
IMILKFDD_00707	6.05e-117	-	-	-	S	-	-	-	Phage capsid family
IMILKFDD_00714	1.73e-134	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
IMILKFDD_00715	2.08e-120	-	-	-	S	-	-	-	Phage tail protein
IMILKFDD_00716	0.0	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
IMILKFDD_00717	1.47e-122	-	-	-	M	-	-	-	Prophage endopeptidase tail
IMILKFDD_00723	8.59e-21	-	-	-	-	-	-	-	-
IMILKFDD_00727	8.1e-110	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMILKFDD_00728	3.38e-89	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IMILKFDD_00729	3.97e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IMILKFDD_00730	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMILKFDD_00731	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IMILKFDD_00732	6.6e-163	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMILKFDD_00733	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IMILKFDD_00734	2e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IMILKFDD_00735	5.6e-17	-	-	-	-	-	-	-	-
IMILKFDD_00736	1.76e-183	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
IMILKFDD_00737	5.19e-56	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
IMILKFDD_00738	2.26e-136	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IMILKFDD_00739	2.49e-96	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IMILKFDD_00740	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMILKFDD_00741	2.53e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IMILKFDD_00742	2.55e-72	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
IMILKFDD_00743	7.34e-54	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMILKFDD_00744	1.69e-164	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IMILKFDD_00745	2.49e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMILKFDD_00746	7.51e-257	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IMILKFDD_00747	1.29e-141	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IMILKFDD_00748	1.95e-235	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IMILKFDD_00749	1.5e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IMILKFDD_00750	1.05e-114	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMILKFDD_00751	2.6e-172	-	-	-	K	-	-	-	Transcriptional regulator
IMILKFDD_00752	7.65e-185	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IMILKFDD_00753	4.04e-148	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
IMILKFDD_00754	4.96e-219	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IMILKFDD_00755	4.96e-111	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IMILKFDD_00757	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IMILKFDD_00758	3.81e-218	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IMILKFDD_00759	8.9e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
IMILKFDD_00760	2.93e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
IMILKFDD_00761	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IMILKFDD_00762	7.12e-50	-	-	-	-	-	-	-	-
IMILKFDD_00765	1.6e-19	-	-	-	D	-	-	-	LPXTG cell wall anchor motif
IMILKFDD_00768	2.37e-184	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
IMILKFDD_00769	9.72e-98	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IMILKFDD_00770	9.44e-131	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMILKFDD_00771	1.76e-232	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IMILKFDD_00772	1.47e-91	-	-	-	L	-	-	-	DNA alkylation repair enzyme
IMILKFDD_00773	1.72e-174	-	-	-	EG	-	-	-	EamA-like transporter family
IMILKFDD_00774	3.9e-190	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IMILKFDD_00775	1.56e-256	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IMILKFDD_00776	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IMILKFDD_00777	8.84e-167	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IMILKFDD_00778	1.34e-220	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IMILKFDD_00779	2e-164	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IMILKFDD_00780	1.21e-104	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IMILKFDD_00782	1.79e-119	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IMILKFDD_00783	1.65e-201	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IMILKFDD_00784	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IMILKFDD_00785	5.64e-256	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IMILKFDD_00786	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IMILKFDD_00787	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IMILKFDD_00788	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IMILKFDD_00789	1.7e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IMILKFDD_00790	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IMILKFDD_00792	6.49e-53	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
IMILKFDD_00793	1.38e-106	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IMILKFDD_00794	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IMILKFDD_00795	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IMILKFDD_00796	7.25e-251	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IMILKFDD_00797	2.07e-52	-	-	-	K	-	-	-	Transcriptional regulator
IMILKFDD_00798	8.36e-148	-	-	-	S	-	-	-	EDD domain protein, DegV family
IMILKFDD_00799	6.76e-92	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
IMILKFDD_00800	2.4e-53	-	-	-	S	-	-	-	ASCH
IMILKFDD_00801	1.85e-236	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMILKFDD_00802	2.87e-98	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IMILKFDD_00803	2.08e-121	-	-	-	EG	-	-	-	EamA-like transporter family
IMILKFDD_00804	7.59e-69	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IMILKFDD_00805	8.53e-30	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
IMILKFDD_00806	9.85e-142	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
IMILKFDD_00807	2.83e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IMILKFDD_00809	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IMILKFDD_00810	1.36e-287	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IMILKFDD_00811	7.47e-219	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IMILKFDD_00812	1e-77	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
IMILKFDD_00813	4.73e-40	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMILKFDD_00814	5.28e-220	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IMILKFDD_00815	1.25e-275	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMILKFDD_00817	3.85e-114	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IMILKFDD_00818	4.63e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMILKFDD_00819	5.92e-40	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IMILKFDD_00820	2.42e-88	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMILKFDD_00821	8.4e-196	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IMILKFDD_00822	4.22e-106	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
IMILKFDD_00823	1.02e-111	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IMILKFDD_00824	1.12e-15	-	-	-	M	-	-	-	Lysin motif
IMILKFDD_00825	4.88e-153	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IMILKFDD_00826	1.2e-78	-	-	-	S	-	-	-	Helix-turn-helix domain
IMILKFDD_00827	2.54e-276	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IMILKFDD_00828	3.42e-59	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
IMILKFDD_00829	2.97e-149	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
IMILKFDD_00830	5.36e-51	-	-	-	-	-	-	-	-
IMILKFDD_00831	2.23e-109	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IMILKFDD_00833	1.26e-235	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IMILKFDD_00834	3.12e-264	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IMILKFDD_00835	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IMILKFDD_00836	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IMILKFDD_00837	2.66e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IMILKFDD_00838	2.12e-87	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IMILKFDD_00839	6.44e-79	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
IMILKFDD_00840	6.63e-167	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IMILKFDD_00841	5.65e-95	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
IMILKFDD_00842	3.35e-123	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
IMILKFDD_00843	1.78e-261	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IMILKFDD_00844	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IMILKFDD_00846	1.61e-101	-	-	-	F	-	-	-	Hydrolase, nudix family
IMILKFDD_00847	1.34e-73	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IMILKFDD_00848	1.64e-87	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IMILKFDD_00849	3.4e-93	-	-	-	M	-	-	-	GNAT acetyltransferase
IMILKFDD_00851	5.57e-12	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
IMILKFDD_00852	8.33e-13	-	-	-	D	-	-	-	Antitoxin Phd_YefM, type II toxin-antitoxin system
IMILKFDD_00853	8.44e-246	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IMILKFDD_00854	5.59e-84	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IMILKFDD_00855	1.52e-236	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IMILKFDD_00856	1.17e-98	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IMILKFDD_00857	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IMILKFDD_00858	1.8e-272	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IMILKFDD_00859	7.59e-185	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
IMILKFDD_00860	7.89e-42	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IMILKFDD_00861	1.06e-131	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IMILKFDD_00863	2.07e-106	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMILKFDD_00864	1.5e-141	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IMILKFDD_00865	9.26e-253	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IMILKFDD_00866	2.65e-35	-	-	-	-	-	-	-	-
IMILKFDD_00867	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
IMILKFDD_00868	4.99e-78	-	-	-	T	-	-	-	Universal stress protein family
IMILKFDD_00870	7.69e-272	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IMILKFDD_00871	3.5e-214	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IMILKFDD_00872	1.39e-142	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IMILKFDD_00873	3.06e-159	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IMILKFDD_00874	1.64e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
IMILKFDD_00875	8.84e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IMILKFDD_00876	2.3e-127	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IMILKFDD_00877	2.7e-79	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMILKFDD_00878	1.7e-76	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMILKFDD_00879	6.85e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IMILKFDD_00880	5.56e-73	-	-	-	-	-	-	-	-
IMILKFDD_00881	4.92e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
IMILKFDD_00882	5.36e-07	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
IMILKFDD_00883	2.76e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
IMILKFDD_00884	0.000912	-	2.7.11.1	-	T	ko:K12132	-	ko00000,ko01000,ko01001	NACHT domain
IMILKFDD_00885	1.73e-274	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IMILKFDD_00886	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IMILKFDD_00887	2.56e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
IMILKFDD_00888	3e-223	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IMILKFDD_00889	7.86e-124	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IMILKFDD_00890	9.73e-90	-	-	-	-	-	-	-	-
IMILKFDD_00892	1.47e-37	-	-	-	S	-	-	-	Cysteine-rich CPCC
IMILKFDD_00894	1.47e-09	-	-	-	M	-	-	-	LysM domain
IMILKFDD_00895	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IMILKFDD_00896	1.55e-37	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
IMILKFDD_00897	3.02e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IMILKFDD_00905	3.37e-81	-	-	-	H	-	-	-	Methyltransferase domain
IMILKFDD_00906	6.84e-55	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
IMILKFDD_00907	2.76e-52	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
IMILKFDD_00909	1.62e-29	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
IMILKFDD_00910	2.29e-51	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IMILKFDD_00912	2.66e-106	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IMILKFDD_00913	1.8e-40	-	-	-	S	-	-	-	CHY zinc finger
IMILKFDD_00914	2.08e-52	ywnA	-	-	K	-	-	-	Transcriptional regulator
IMILKFDD_00915	8.23e-105	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
IMILKFDD_00918	8.79e-155	-	-	-	M	-	-	-	Glycosyl transferases group 1
IMILKFDD_00919	2.03e-77	-	-	-	M	-	-	-	Glycosyl transferases group 1
IMILKFDD_00920	3.52e-225	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMILKFDD_00921	1.02e-181	-	5.1.3.6	-	GM	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	RmlD substrate binding domain
IMILKFDD_00922	5.97e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IMILKFDD_00923	3.08e-32	-	-	-	M	-	-	-	Glycosyl transferase
IMILKFDD_00924	2.54e-12	-	-	-	M	-	-	-	Glycosyl transferases group 1
IMILKFDD_00925	4.62e-109	-	-	-	S	-	-	-	Glycosyltransferase WbsX
IMILKFDD_00926	4.44e-29	-	2.8.2.1	-	M	ko:K01014	ko05204,map05204	ko00000,ko00001,ko01000	transferase activity, transferring glycosyl groups
IMILKFDD_00927	3.45e-51	-	-	-	-	-	-	-	-
IMILKFDD_00929	3.65e-70	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IMILKFDD_00930	1.19e-46	rfbF	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
IMILKFDD_00931	1.84e-88	-	-	-	M	-	-	-	Glycosyltransferase Family 4
IMILKFDD_00932	4.2e-92	-	-	-	M	-	-	-	glycosyl transferase group 1
IMILKFDD_00933	7.01e-67	-	-	-	M	-	-	-	glycosyl transferase group 1
IMILKFDD_00934	3.83e-22	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.87
IMILKFDD_00935	3.16e-157	-	-	-	M	-	-	-	Glycosyl transferases group 1
IMILKFDD_00936	2.02e-52	-	-	-	S	ko:K13006,ko:K19429	-	ko00000,ko01000,ko01005	Bacterial transferase hexapeptide (six repeats)
IMILKFDD_00937	2.94e-98	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
IMILKFDD_00938	7.69e-137	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMILKFDD_00939	1.86e-59	epsN	-	-	M	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IMILKFDD_00940	1.34e-104	-	-	-	GM	-	-	-	CoA-binding domain
IMILKFDD_00941	2.9e-154	capD	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
IMILKFDD_00942	1.57e-59	-	-	-	M	-	-	-	Chain length determinant protein
IMILKFDD_00943	2.35e-52	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IMILKFDD_00944	9.71e-225	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IMILKFDD_00945	5.48e-82	-	-	-	-	-	-	-	-
IMILKFDD_00946	4.55e-105	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IMILKFDD_00947	1.01e-143	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IMILKFDD_00948	9.13e-77	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IMILKFDD_00949	2.31e-239	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IMILKFDD_00950	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IMILKFDD_00951	1.12e-266	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IMILKFDD_00953	8.38e-80	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IMILKFDD_00954	5.51e-69	-	-	-	S	-	-	-	Membrane
IMILKFDD_00955	2.07e-231	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IMILKFDD_00956	2.34e-155	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IMILKFDD_00957	1.05e-76	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IMILKFDD_00958	6.64e-231	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IMILKFDD_00959	3.76e-32	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IMILKFDD_00960	8.4e-66	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IMILKFDD_00961	6.94e-117	tnp2	-	-	L	-	-	-	Transposase
IMILKFDD_00962	6.61e-36	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IMILKFDD_00963	1.53e-151	-	-	-	T	-	-	-	diguanylate cyclase activity
IMILKFDD_00964	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
IMILKFDD_00965	8.55e-256	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
IMILKFDD_00966	4.02e-254	-	-	-	S	-	-	-	Protein conserved in bacteria
IMILKFDD_00967	7.65e-237	-	-	-	-	-	-	-	-
IMILKFDD_00968	3.21e-162	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IMILKFDD_00969	3.88e-17	-	-	-	T	-	-	-	diguanylate cyclase
IMILKFDD_00970	4.76e-181	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
IMILKFDD_00971	6.22e-197	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IMILKFDD_00972	5.72e-133	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
IMILKFDD_00973	1.86e-120	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IMILKFDD_00974	1.63e-274	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
IMILKFDD_00975	1.34e-254	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IMILKFDD_00976	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
IMILKFDD_00977	1.84e-244	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
IMILKFDD_00978	4.47e-201	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IMILKFDD_00979	1.16e-47	-	-	-	M	-	-	-	LysM domain
IMILKFDD_00980	1.38e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
IMILKFDD_00981	1.8e-67	-	-	-	M	-	-	-	LysM domain protein
IMILKFDD_00982	1.29e-114	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IMILKFDD_00983	4.26e-108	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
IMILKFDD_00985	5.69e-91	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
IMILKFDD_00986	4.52e-131	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMILKFDD_00987	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMILKFDD_00988	1.61e-91	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
IMILKFDD_00989	1.4e-104	ylmH	-	-	S	-	-	-	S4 domain protein
IMILKFDD_00990	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IMILKFDD_00991	8.14e-43	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IMILKFDD_00992	4.52e-229	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMILKFDD_00993	1.22e-239	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IMILKFDD_00994	6.44e-76	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IMILKFDD_00995	2.12e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMILKFDD_00996	4.21e-233	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMILKFDD_00997	3.64e-172	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMILKFDD_00998	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IMILKFDD_00999	1.49e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
IMILKFDD_01000	1.05e-179	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IMILKFDD_01001	5.35e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IMILKFDD_01003	2.55e-194	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
IMILKFDD_01004	1.16e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IMILKFDD_01005	9.13e-124	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IMILKFDD_01006	5.62e-139	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IMILKFDD_01007	1.41e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_01008	3.02e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IMILKFDD_01009	7.95e-163	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
IMILKFDD_01010	1.02e-97	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IMILKFDD_01011	9.34e-71	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
IMILKFDD_01012	1.64e-121	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IMILKFDD_01013	2.35e-207	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IMILKFDD_01014	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
IMILKFDD_01015	2.27e-102	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IMILKFDD_01016	1.21e-169	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IMILKFDD_01017	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IMILKFDD_01018	1.01e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMILKFDD_01019	1.45e-204	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IMILKFDD_01020	3.25e-223	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IMILKFDD_01021	6.33e-73	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IMILKFDD_01022	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMILKFDD_01023	2.29e-28	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IMILKFDD_01024	3.67e-244	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IMILKFDD_01026	6.35e-97	uspA	-	-	T	-	-	-	universal stress protein
IMILKFDD_01027	4.17e-70	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IMILKFDD_01028	5.17e-253	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IMILKFDD_01029	2.41e-157	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IMILKFDD_01031	1.03e-96	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IMILKFDD_01032	1.21e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
IMILKFDD_01033	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IMILKFDD_01034	0.0	-	-	-	S	-	-	-	membrane
IMILKFDD_01035	3.03e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMILKFDD_01036	4.1e-267	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IMILKFDD_01037	4.8e-128	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
IMILKFDD_01038	4.32e-179	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IMILKFDD_01040	1.68e-22	-	-	-	-	-	-	-	-
IMILKFDD_01041	3.6e-255	oatA	-	-	I	-	-	-	Acyltransferase
IMILKFDD_01042	1.35e-271	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMILKFDD_01043	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IMILKFDD_01044	1.41e-177	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMILKFDD_01047	7.32e-53	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IMILKFDD_01048	4.41e-94	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMILKFDD_01049	3.55e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IMILKFDD_01050	5.23e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IMILKFDD_01051	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IMILKFDD_01052	7.68e-20	cvpA	-	-	S	-	-	-	Colicin V production protein
IMILKFDD_01053	3e-16	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IMILKFDD_01054	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IMILKFDD_01055	3.16e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMILKFDD_01056	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IMILKFDD_01057	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMILKFDD_01058	1.74e-235	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IMILKFDD_01059	8.82e-154	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IMILKFDD_01060	3.5e-18	-	-	-	-	-	-	-	-
IMILKFDD_01061	6.8e-185	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMILKFDD_01062	4.44e-85	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
IMILKFDD_01063	4.06e-310	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
IMILKFDD_01064	3.54e-150	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
IMILKFDD_01065	2.92e-264	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
IMILKFDD_01067	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
IMILKFDD_01069	1.06e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
IMILKFDD_01070	5.96e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IMILKFDD_01071	2.88e-231	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IMILKFDD_01072	1.45e-193	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IMILKFDD_01073	2.19e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IMILKFDD_01074	1.41e-287	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMILKFDD_01075	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMILKFDD_01076	3.58e-255	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IMILKFDD_01077	1.06e-202	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMILKFDD_01078	2.09e-111	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMILKFDD_01079	1.06e-84	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
IMILKFDD_01080	7.38e-116	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IMILKFDD_01081	4.91e-184	ymfH	-	-	S	-	-	-	Peptidase M16
IMILKFDD_01082	7.37e-137	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IMILKFDD_01083	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IMILKFDD_01084	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IMILKFDD_01085	5e-125	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
IMILKFDD_01086	1.44e-83	-	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
IMILKFDD_01087	1.61e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IMILKFDD_01088	3.47e-250	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IMILKFDD_01089	8.5e-24	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
IMILKFDD_01090	1.61e-165	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IMILKFDD_01091	1.59e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
IMILKFDD_01092	1.1e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMILKFDD_01093	2.27e-87	ybbR	-	-	S	-	-	-	YbbR-like protein
IMILKFDD_01094	4.8e-163	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IMILKFDD_01095	5.56e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
IMILKFDD_01096	3.49e-145	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IMILKFDD_01097	2.74e-89	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IMILKFDD_01098	1e-72	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IMILKFDD_01099	2.01e-180	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IMILKFDD_01100	1.07e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMILKFDD_01101	1.68e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IMILKFDD_01102	1.94e-53	-	-	-	-	-	-	-	-
IMILKFDD_01103	1.75e-90	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IMILKFDD_01104	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IMILKFDD_01105	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IMILKFDD_01106	3.14e-224	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IMILKFDD_01107	7.65e-189	-	-	-	E	-	-	-	Major Facilitator Superfamily
IMILKFDD_01108	4.69e-212	yclK	-	-	T	-	-	-	Histidine kinase
IMILKFDD_01109	1.37e-134	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
IMILKFDD_01110	2.02e-167	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMILKFDD_01111	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IMILKFDD_01112	2.01e-164	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IMILKFDD_01113	1.15e-263	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IMILKFDD_01114	1.19e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IMILKFDD_01115	2.76e-175	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
IMILKFDD_01117	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IMILKFDD_01118	2.05e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IMILKFDD_01119	9.11e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IMILKFDD_01120	7.15e-161	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IMILKFDD_01121	7.97e-102	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
IMILKFDD_01122	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IMILKFDD_01123	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IMILKFDD_01124	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IMILKFDD_01125	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IMILKFDD_01126	3.37e-142	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMILKFDD_01127	8.3e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IMILKFDD_01128	2.17e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
IMILKFDD_01129	1.44e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
IMILKFDD_01130	5.23e-104	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IMILKFDD_01131	1.7e-109	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IMILKFDD_01132	7e-81	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
IMILKFDD_01133	1.85e-206	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IMILKFDD_01134	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IMILKFDD_01135	3.91e-119	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
IMILKFDD_01136	7.08e-105	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IMILKFDD_01137	7.98e-69	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IMILKFDD_01138	1.23e-158	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IMILKFDD_01139	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
IMILKFDD_01140	0.0	ydaO	-	-	E	-	-	-	amino acid
IMILKFDD_01141	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
IMILKFDD_01142	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IMILKFDD_01143	1.98e-45	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMILKFDD_01144	1.43e-41	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IMILKFDD_01145	2.16e-126	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IMILKFDD_01146	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IMILKFDD_01147	4.15e-205	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMILKFDD_01148	1.9e-19	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IMILKFDD_01149	6.07e-87	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IMILKFDD_01150	2.82e-178	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
IMILKFDD_01151	6.03e-105	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IMILKFDD_01152	7.55e-120	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMILKFDD_01153	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IMILKFDD_01154	3.28e-105	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IMILKFDD_01155	3.09e-83	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMILKFDD_01156	2.93e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IMILKFDD_01157	6.62e-126	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMILKFDD_01158	3.64e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IMILKFDD_01159	2.34e-269	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMILKFDD_01160	2.23e-80	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IMILKFDD_01161	1.11e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IMILKFDD_01162	3.91e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IMILKFDD_01163	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
IMILKFDD_01164	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMILKFDD_01165	1.1e-203	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMILKFDD_01166	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IMILKFDD_01167	7.33e-71	-	-	-	-	-	-	-	-
IMILKFDD_01168	2.18e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IMILKFDD_01169	2.21e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMILKFDD_01170	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IMILKFDD_01171	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMILKFDD_01172	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IMILKFDD_01173	6.21e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IMILKFDD_01174	3.3e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IMILKFDD_01175	1.93e-92	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
IMILKFDD_01176	2.29e-139	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMILKFDD_01177	4.02e-72	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IMILKFDD_01178	2.26e-263	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IMILKFDD_01179	4.97e-311	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMILKFDD_01180	1.38e-195	yacL	-	-	S	-	-	-	domain protein
IMILKFDD_01181	2.79e-284	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMILKFDD_01182	2.38e-95	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
IMILKFDD_01183	1.17e-25	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
IMILKFDD_01184	5.18e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IMILKFDD_01185	3.93e-45	-	-	-	S	-	-	-	Enterocin A Immunity
IMILKFDD_01186	2.04e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IMILKFDD_01187	2.13e-163	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
IMILKFDD_01188	1.02e-145	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMILKFDD_01190	3.25e-54	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IMILKFDD_01191	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
IMILKFDD_01192	1.31e-165	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IMILKFDD_01193	3.1e-307	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IMILKFDD_01194	3.32e-113	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IMILKFDD_01195	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
IMILKFDD_01196	3.5e-114	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMILKFDD_01197	3.4e-119	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IMILKFDD_01198	1.59e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
IMILKFDD_01199	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IMILKFDD_01200	5.02e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IMILKFDD_01201	4.4e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IMILKFDD_01202	5.64e-69	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
IMILKFDD_01203	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IMILKFDD_01204	3.98e-151	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
IMILKFDD_01205	1.31e-154	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
IMILKFDD_01206	2.43e-90	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
IMILKFDD_01207	1.53e-214	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IMILKFDD_01208	1e-228	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
IMILKFDD_01209	0.0	-	-	-	E	-	-	-	Amino acid permease
IMILKFDD_01210	1.29e-109	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
IMILKFDD_01211	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IMILKFDD_01212	1.42e-18	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IMILKFDD_01213	5.58e-68	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IMILKFDD_01214	3.51e-270	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
IMILKFDD_01215	1.64e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
IMILKFDD_01216	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IMILKFDD_01219	2.96e-203	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IMILKFDD_01220	7.62e-161	mocA	-	-	S	-	-	-	Oxidoreductase
IMILKFDD_01221	7.99e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
IMILKFDD_01222	3.02e-213	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IMILKFDD_01223	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IMILKFDD_01224	1.82e-243	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IMILKFDD_01225	4.5e-156	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IMILKFDD_01226	1.95e-208	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMILKFDD_01227	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IMILKFDD_01228	2.39e-271	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IMILKFDD_01229	2.8e-46	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
IMILKFDD_01230	1.46e-277	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
IMILKFDD_01231	6.52e-262	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IMILKFDD_01232	1.87e-41	-	-	-	K	-	-	-	GNAT family
IMILKFDD_01233	1.96e-54	-	-	-	-	-	-	-	-
IMILKFDD_01235	3.65e-228	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
IMILKFDD_01236	7.5e-118	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IMILKFDD_01237	1.79e-148	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMILKFDD_01238	5.56e-124	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IMILKFDD_01239	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IMILKFDD_01240	2.27e-48	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IMILKFDD_01241	9.01e-254	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IMILKFDD_01242	1.31e-94	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IMILKFDD_01243	2.58e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
IMILKFDD_01244	8.09e-82	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IMILKFDD_01245	1.24e-161	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
IMILKFDD_01246	6.85e-313	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
IMILKFDD_01247	7.97e-90	mleR	-	-	K	-	-	-	LysR family
IMILKFDD_01248	5.18e-74	napB	-	-	K	-	-	-	transcriptional
IMILKFDD_01249	1.35e-51	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IMILKFDD_01250	6.59e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
IMILKFDD_01251	2.15e-59	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
IMILKFDD_01252	5.86e-287	-	-	-	M	-	-	-	Rib/alpha-like repeat
IMILKFDD_01254	1.7e-129	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IMILKFDD_01255	9.53e-79	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
IMILKFDD_01256	1.54e-203	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMILKFDD_01257	2.59e-50	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IMILKFDD_01258	1.09e-268	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IMILKFDD_01259	3.94e-249	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IMILKFDD_01260	4.35e-301	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IMILKFDD_01261	2.77e-19	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
IMILKFDD_01262	7.05e-222	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
IMILKFDD_01263	6e-76	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IMILKFDD_01264	2.11e-122	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMILKFDD_01265	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IMILKFDD_01266	5.1e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IMILKFDD_01267	1.84e-185	-	-	-	C	-	-	-	Oxidoreductase
IMILKFDD_01268	7.03e-208	spoVK	-	-	O	ko:K06413	-	ko00000	PFAM ATPase family associated with various cellular activities (AAA)
IMILKFDD_01269	7.43e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
IMILKFDD_01270	1.22e-74	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
IMILKFDD_01271	2.62e-133	-	-	-	S	-	-	-	Domain of unknown function (DUF4343)
IMILKFDD_01272	0.0	-	-	-	L	-	-	-	helicase activity
IMILKFDD_01273	4.53e-265	-	-	-	K	-	-	-	DNA binding
IMILKFDD_01274	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
IMILKFDD_01275	8.59e-287	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
IMILKFDD_01276	1.21e-212	mcrC	-	-	V	ko:K19147	-	ko00000,ko02048	Psort location Cytoplasmic, score
IMILKFDD_01277	0.0	mcrB	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	ATPase family associated with various cellular activities (AAA)
IMILKFDD_01279	8.77e-268	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMILKFDD_01280	1.46e-182	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IMILKFDD_01281	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMILKFDD_01282	1.98e-292	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IMILKFDD_01283	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMILKFDD_01284	6.9e-205	camS	-	-	S	-	-	-	sex pheromone
IMILKFDD_01285	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMILKFDD_01286	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IMILKFDD_01287	1.13e-180	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IMILKFDD_01289	6.22e-242	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IMILKFDD_01290	6.3e-104	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IMILKFDD_01291	6.66e-76	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IMILKFDD_01292	9.32e-242	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IMILKFDD_01293	5.66e-246	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IMILKFDD_01294	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IMILKFDD_01295	5.21e-226	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMILKFDD_01297	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IMILKFDD_01298	9.77e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMILKFDD_01299	2.65e-166	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IMILKFDD_01300	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMILKFDD_01301	2.04e-99	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IMILKFDD_01302	1.14e-118	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IMILKFDD_01303	1.23e-62	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
IMILKFDD_01304	1.05e-28	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IMILKFDD_01305	1.56e-42	yabO	-	-	J	-	-	-	S4 domain protein
IMILKFDD_01306	1.64e-173	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IMILKFDD_01307	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMILKFDD_01308	1.45e-95	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IMILKFDD_01309	8.16e-202	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IMILKFDD_01310	1.08e-26	-	-	-	V	ko:K07448,ko:K07449	-	ko00000,ko02048	Restriction endonuclease
IMILKFDD_01311	3.46e-107	-	-	-	S	-	-	-	(CBS) domain
IMILKFDD_01312	3.13e-180	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMILKFDD_01313	1.66e-260	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMILKFDD_01314	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IMILKFDD_01315	8.18e-73	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
IMILKFDD_01316	9.32e-131	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
IMILKFDD_01317	1.17e-141	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IMILKFDD_01318	2.6e-62	-	-	-	M	-	-	-	LysM domain protein
IMILKFDD_01319	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IMILKFDD_01320	6.4e-111	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IMILKFDD_01321	2.98e-41	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
IMILKFDD_01322	2.16e-137	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IMILKFDD_01323	3.65e-110	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_01324	3.37e-84	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IMILKFDD_01325	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IMILKFDD_01326	4.89e-308	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IMILKFDD_01328	1.88e-185	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IMILKFDD_01329	1.1e-270	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IMILKFDD_01330	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IMILKFDD_01331	4.81e-230	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IMILKFDD_01332	1.2e-144	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
IMILKFDD_01333	1.08e-74	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
IMILKFDD_01334	7.12e-68	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IMILKFDD_01335	4.59e-16	epsJ2	-	-	S	-	-	-	Glycosyltransferase like family 2
IMILKFDD_01336	5.71e-28	-	-	-	-	-	-	-	-
IMILKFDD_01337	3.54e-111	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IMILKFDD_01338	2.69e-71	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IMILKFDD_01339	1.49e-229	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
IMILKFDD_01340	5.04e-128	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
IMILKFDD_01341	2.17e-18	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMILKFDD_01342	1.2e-173	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IMILKFDD_01343	2.22e-63	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IMILKFDD_01344	1.64e-46	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IMILKFDD_01345	1.43e-179	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
IMILKFDD_01346	1.2e-99	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
IMILKFDD_01347	2.51e-126	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
IMILKFDD_01348	2.25e-213	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Xylulose kinase
IMILKFDD_01349	3.93e-116	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IMILKFDD_01350	5.62e-92	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
IMILKFDD_01351	1.29e-76	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IMILKFDD_01352	7.18e-51	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IMILKFDD_01353	3.99e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IMILKFDD_01354	1.41e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IMILKFDD_01355	2.49e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IMILKFDD_01356	1.29e-51	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IMILKFDD_01357	4.63e-76	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IMILKFDD_01358	5.17e-149	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IMILKFDD_01359	1.51e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
IMILKFDD_01360	2.16e-120	baeS	-	-	T	-	-	-	Histidine kinase
IMILKFDD_01361	7.63e-102	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
IMILKFDD_01362	3.19e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IMILKFDD_01363	1.97e-152	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IMILKFDD_01364	5.89e-188	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IMILKFDD_01365	1.61e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
IMILKFDD_01366	7.22e-27	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
IMILKFDD_01367	6.4e-152	-	-	-	V	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IMILKFDD_01368	4.9e-158	-	-	-	V	ko:K20460,ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IMILKFDD_01369	1.11e-207	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IMILKFDD_01370	2.3e-159	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMILKFDD_01371	1.56e-296	-	-	-	T	-	-	-	Histidine kinase
IMILKFDD_01372	2.35e-120	-	-	-	O	-	-	-	Ergosterol biosynthesis ERG4/ERG24 family
IMILKFDD_01373	8.85e-76	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
IMILKFDD_01374	3.78e-48	-	-	-	S	ko:K19165	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
IMILKFDD_01375	4.96e-132	-	-	-	L	-	-	-	ATPase involved in DNA repair
IMILKFDD_01376	2.71e-223	-	-	-	L	-	-	-	ATPase involved in DNA repair
IMILKFDD_01377	6.47e-87	-	-	-	-	-	-	-	-
IMILKFDD_01378	2.97e-102	-	-	-	T	-	-	-	Nacht domain
IMILKFDD_01379	3.4e-90	-	-	-	T	-	-	-	Nacht domain
IMILKFDD_01380	1.37e-30	-	-	-	-	-	-	-	-
IMILKFDD_01381	7.13e-118	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
IMILKFDD_01382	8.55e-187	-	-	-	IQ	-	-	-	KR domain
IMILKFDD_01383	3.26e-120	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IMILKFDD_01385	2.5e-103	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
IMILKFDD_01386	1.3e-33	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
IMILKFDD_01388	3.95e-266	cna	-	-	M	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IMILKFDD_01389	0.0	-	-	-	M	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IMILKFDD_01390	2.29e-79	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IMILKFDD_01391	8.55e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMILKFDD_01392	6.22e-160	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IMILKFDD_01393	1.03e-136	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMILKFDD_01394	8.76e-140	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMILKFDD_01395	3.22e-127	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMILKFDD_01396	1.82e-70	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IMILKFDD_01397	2.74e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMILKFDD_01398	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMILKFDD_01399	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMILKFDD_01400	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IMILKFDD_01401	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IMILKFDD_01402	5.17e-142	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IMILKFDD_01403	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IMILKFDD_01404	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IMILKFDD_01405	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IMILKFDD_01406	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMILKFDD_01407	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMILKFDD_01408	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMILKFDD_01409	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMILKFDD_01410	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMILKFDD_01411	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMILKFDD_01412	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMILKFDD_01413	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMILKFDD_01414	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMILKFDD_01415	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IMILKFDD_01416	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMILKFDD_01417	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMILKFDD_01418	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMILKFDD_01419	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IMILKFDD_01420	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMILKFDD_01421	1.34e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IMILKFDD_01422	6.55e-130	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IMILKFDD_01423	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMILKFDD_01424	3.24e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IMILKFDD_01425	2.1e-218	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMILKFDD_01426	1.07e-100	-	-	-	K	-	-	-	rpiR family
IMILKFDD_01427	1.63e-68	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
IMILKFDD_01428	1.38e-186	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IMILKFDD_01429	2.79e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IMILKFDD_01430	8.22e-240	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IMILKFDD_01431	1.88e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IMILKFDD_01432	4.89e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IMILKFDD_01433	2.79e-125	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IMILKFDD_01434	2.45e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_01435	3.68e-17	-	-	-	-	-	-	-	-
IMILKFDD_01436	3.67e-122	-	-	-	-	-	-	-	-
IMILKFDD_01437	2.09e-16	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
IMILKFDD_01438	2.87e-68	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IMILKFDD_01439	1.24e-268	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
IMILKFDD_01440	5.89e-316	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IMILKFDD_01441	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IMILKFDD_01442	1.01e-100	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IMILKFDD_01443	3.39e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
IMILKFDD_01444	7.84e-33	-	-	-	-	-	-	-	-
IMILKFDD_01445	1.13e-93	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IMILKFDD_01446	3.21e-162	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IMILKFDD_01447	2.78e-126	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IMILKFDD_01448	3.49e-86	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMILKFDD_01449	6.88e-200	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
IMILKFDD_01450	1.97e-174	-	-	-	V	-	-	-	MatE
IMILKFDD_01451	1.32e-57	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IMILKFDD_01452	5.52e-111	-	-	-	S	-	-	-	Alpha beta hydrolase
IMILKFDD_01453	1.06e-121	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IMILKFDD_01454	3.68e-219	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMILKFDD_01455	1.24e-137	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
IMILKFDD_01456	3.5e-128	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IMILKFDD_01457	8.54e-45	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
IMILKFDD_01458	1.09e-68	ccl	-	-	S	-	-	-	QueT transporter
IMILKFDD_01460	6.6e-84	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IMILKFDD_01461	2.37e-28	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMILKFDD_01462	3.11e-28	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMILKFDD_01463	7.86e-46	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IMILKFDD_01464	1.97e-108	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IMILKFDD_01465	1.52e-157	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IMILKFDD_01466	9.79e-65	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IMILKFDD_01467	9.59e-104	-	-	-	S	-	-	-	Putative threonine/serine exporter
IMILKFDD_01468	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IMILKFDD_01469	2.93e-114	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
IMILKFDD_01470	3.07e-119	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IMILKFDD_01471	4.75e-26	-	-	-	-	-	-	-	-
IMILKFDD_01472	1.3e-74	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
IMILKFDD_01473	4.48e-24	-	-	-	-	-	-	-	-
IMILKFDD_01474	3.45e-81	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IMILKFDD_01475	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
IMILKFDD_01476	3.58e-132	-	-	-	E	-	-	-	AzlC protein
IMILKFDD_01477	2.11e-23	-	-	-	-	-	-	-	-
IMILKFDD_01478	5.1e-163	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IMILKFDD_01479	1.53e-158	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
IMILKFDD_01487	2.43e-09	-	-	-	S	-	-	-	Mor transcription activator family
IMILKFDD_01488	3.27e-73	-	-	-	K	-	-	-	WYL domain
IMILKFDD_01489	3.53e-158	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IMILKFDD_01490	1.81e-216	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IMILKFDD_01491	7.91e-149	ydbI	-	-	K	-	-	-	AI-2E family transporter
IMILKFDD_01492	2.37e-75	-	-	-	EG	-	-	-	EamA-like transporter family
IMILKFDD_01493	1.3e-97	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
IMILKFDD_01494	4.74e-104	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IMILKFDD_01495	3.19e-15	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IMILKFDD_01496	4.46e-86	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IMILKFDD_01497	5.43e-209	-	-	-	C	-	-	-	Luciferase-like monooxygenase
IMILKFDD_01498	1.7e-55	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IMILKFDD_01499	6.68e-219	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMILKFDD_01500	2.09e-132	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IMILKFDD_01501	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IMILKFDD_01502	3.43e-106	pncA	-	-	Q	-	-	-	isochorismatase
IMILKFDD_01503	1.87e-80	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
IMILKFDD_01504	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IMILKFDD_01505	1.68e-108	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
IMILKFDD_01506	5.26e-316	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IMILKFDD_01507	2.77e-211	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IMILKFDD_01509	1.61e-229	XK27_08315	-	-	M	-	-	-	Sulfatase
IMILKFDD_01510	4.61e-67	-	-	-	S	-	-	-	peptidoglycan catabolic process
IMILKFDD_01511	1.82e-197	-	-	-	M	-	-	-	Belongs to the BCCT transporter (TC 2.A.15) family
IMILKFDD_01512	8.79e-109	-	-	-	M	-	-	-	Nucleotidyl transferase
IMILKFDD_01513	8.04e-220	-	-	-	M	-	-	-	Choline/ethanolamine kinase
IMILKFDD_01514	4.64e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IMILKFDD_01515	1.46e-213	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IMILKFDD_01516	1.21e-160	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IMILKFDD_01517	2.42e-222	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IMILKFDD_01518	1.52e-153	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
IMILKFDD_01519	4.55e-20	-	-	-	-	-	-	-	-
IMILKFDD_01520	4.67e-91	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IMILKFDD_01521	4.09e-183	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
IMILKFDD_01522	6.99e-66	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
IMILKFDD_01523	8.36e-196	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
IMILKFDD_01524	1.23e-85	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IMILKFDD_01525	3.27e-120	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IMILKFDD_01526	7.97e-206	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IMILKFDD_01527	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IMILKFDD_01529	2.97e-193	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IMILKFDD_01530	3.98e-43	-	-	-	S	-	-	-	Acyltransferase family
IMILKFDD_01531	1.43e-141	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
IMILKFDD_01532	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
IMILKFDD_01534	9.15e-11	-	-	-	S	-	-	-	Acyltransferase family
IMILKFDD_01538	2.04e-79	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IMILKFDD_01539	2.14e-92	licD1	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
IMILKFDD_01540	1.74e-67	-	-	-	-	-	-	-	-
IMILKFDD_01541	4.73e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IMILKFDD_01542	1.21e-83	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
IMILKFDD_01543	4.86e-115	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
IMILKFDD_01544	9.91e-47	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IMILKFDD_01545	6.48e-79	-	-	-	D	-	-	-	Peptidase family M23
IMILKFDD_01547	9.38e-161	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IMILKFDD_01548	3.12e-214	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IMILKFDD_01549	9.2e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IMILKFDD_01550	9.87e-184	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IMILKFDD_01551	1.19e-115	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
IMILKFDD_01552	7.11e-75	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
IMILKFDD_01553	2.34e-47	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IMILKFDD_01554	3.44e-26	-	-	-	L	ko:K07482	-	ko00000	Integrase
IMILKFDD_01555	4.8e-95	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IMILKFDD_01556	7.64e-27	-	-	-	-	-	-	-	-
IMILKFDD_01557	1.3e-65	-	-	-	K	-	-	-	SIR2-like domain
IMILKFDD_01558	6.37e-141	-	-	-	K	-	-	-	IrrE N-terminal-like domain
IMILKFDD_01560	1.64e-44	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
IMILKFDD_01561	5.89e-60	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
IMILKFDD_01562	7.73e-62	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
IMILKFDD_01563	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IMILKFDD_01564	9.14e-170	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IMILKFDD_01565	3.94e-56	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IMILKFDD_01566	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_01567	2e-240	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IMILKFDD_01568	6.18e-267	potE	-	-	E	-	-	-	Amino Acid
IMILKFDD_01569	2.51e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
IMILKFDD_01570	1.78e-171	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
IMILKFDD_01571	6.25e-77	-	-	-	S	-	-	-	Glycosyltransferase like family 2
IMILKFDD_01572	2.44e-149	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IMILKFDD_01573	2.09e-46	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IMILKFDD_01574	1.3e-114	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IMILKFDD_01575	1.03e-81	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IMILKFDD_01576	3.16e-192	-	-	-	EGP	-	-	-	Major Facilitator
IMILKFDD_01578	1.09e-87	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IMILKFDD_01579	2.64e-35	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
IMILKFDD_01580	7.64e-114	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IMILKFDD_01581	3.49e-130	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IMILKFDD_01582	1.98e-71	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IMILKFDD_01583	6.01e-139	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
IMILKFDD_01584	1.6e-126	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IMILKFDD_01585	5.14e-132	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IMILKFDD_01586	2.75e-46	-	-	-	-	-	-	-	-
IMILKFDD_01587	3.04e-20	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
IMILKFDD_01588	2.21e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IMILKFDD_01589	6.91e-241	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IMILKFDD_01590	8.92e-33	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IMILKFDD_01591	2.39e-137	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IMILKFDD_01592	5.38e-153	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
IMILKFDD_01593	9.15e-85	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IMILKFDD_01594	7.29e-130	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IMILKFDD_01595	4.74e-161	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IMILKFDD_01596	2.48e-89	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
IMILKFDD_01597	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IMILKFDD_01598	1.36e-78	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
IMILKFDD_01599	6.05e-94	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IMILKFDD_01601	2.06e-82	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
IMILKFDD_01602	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IMILKFDD_01603	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IMILKFDD_01604	1.75e-45	-	-	-	-	-	-	-	-
IMILKFDD_01605	1.86e-178	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMILKFDD_01606	1.42e-197	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMILKFDD_01607	1.11e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMILKFDD_01608	1.91e-197	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IMILKFDD_01609	4.21e-53	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
IMILKFDD_01611	3.12e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_01612	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
IMILKFDD_01613	2.84e-234	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
IMILKFDD_01614	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IMILKFDD_01615	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IMILKFDD_01616	6.4e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
IMILKFDD_01617	1.86e-49	-	-	-	K	-	-	-	Transcriptional regulator
IMILKFDD_01618	3.36e-122	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IMILKFDD_01619	1.17e-127	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_01620	3.9e-134	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IMILKFDD_01621	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IMILKFDD_01622	1.25e-256	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
IMILKFDD_01623	2.84e-220	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IMILKFDD_01624	3.08e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IMILKFDD_01625	1.7e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
IMILKFDD_01626	4.9e-89	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
IMILKFDD_01627	8.78e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
IMILKFDD_01628	3.63e-145	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
IMILKFDD_01629	2.02e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IMILKFDD_01630	6.79e-263	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IMILKFDD_01632	8.35e-141	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IMILKFDD_01633	4.35e-240	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
IMILKFDD_01634	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
IMILKFDD_01635	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
IMILKFDD_01636	3.49e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
IMILKFDD_01637	1.32e-74	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
IMILKFDD_01638	1.71e-97	azlC	-	-	E	-	-	-	branched-chain amino acid
IMILKFDD_01639	5.49e-91	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IMILKFDD_01640	2.04e-164	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMILKFDD_01641	6.06e-207	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMILKFDD_01642	3.33e-97	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
IMILKFDD_01643	6.4e-63	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
IMILKFDD_01644	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IMILKFDD_01645	2.21e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IMILKFDD_01646	4.46e-70	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
IMILKFDD_01647	1.3e-67	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IMILKFDD_01648	8.75e-60	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
IMILKFDD_01649	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IMILKFDD_01650	3.19e-139	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
IMILKFDD_01652	2.05e-86	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IMILKFDD_01653	5.56e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IMILKFDD_01654	1.3e-52	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
IMILKFDD_01656	4.2e-45	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
IMILKFDD_01657	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IMILKFDD_01658	6.7e-122	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_01659	4.5e-25	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IMILKFDD_01665	1.16e-93	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IMILKFDD_01666	9.06e-152	ytbE	-	-	S	-	-	-	reductase
IMILKFDD_01667	1.22e-57	ytcD	-	-	K	-	-	-	HxlR-like helix-turn-helix
IMILKFDD_01668	2.53e-130	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IMILKFDD_01669	1.78e-20	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMILKFDD_01670	1.03e-59	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IMILKFDD_01671	1.17e-30	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IMILKFDD_01672	5.32e-191	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
IMILKFDD_01674	2.61e-51	-	-	-	K	-	-	-	LytTr DNA-binding domain
IMILKFDD_01675	9.27e-145	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
IMILKFDD_01676	5.54e-264	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IMILKFDD_01677	1.85e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
IMILKFDD_01678	9.89e-197	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IMILKFDD_01679	3.5e-229	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IMILKFDD_01680	7.43e-217	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMILKFDD_01681	1.97e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMILKFDD_01682	2.65e-255	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IMILKFDD_01683	5.46e-276	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IMILKFDD_01684	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMILKFDD_01685	7.69e-73	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IMILKFDD_01686	1.28e-77	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
IMILKFDD_01687	9.35e-314	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IMILKFDD_01688	4.15e-26	-	-	-	S	-	-	-	Cupredoxin-like domain
IMILKFDD_01689	5.2e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
IMILKFDD_01690	2.04e-189	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IMILKFDD_01691	1.96e-29	-	-	-	K	-	-	-	transcriptional regulator
IMILKFDD_01692	2.64e-98	-	-	-	S	-	-	-	intracellular protease amidase
IMILKFDD_01693	9.64e-168	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
IMILKFDD_01694	3.48e-143	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IMILKFDD_01695	2.06e-291	treC	-	-	G	-	-	-	Psort location Cytoplasmic, score
IMILKFDD_01696	5.79e-51	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IMILKFDD_01697	1.68e-157	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IMILKFDD_01698	7.67e-139	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
IMILKFDD_01699	1.32e-84	-	-	-	G	-	-	-	PTS system sorbose subfamily IIB component
IMILKFDD_01700	6.73e-102	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IMILKFDD_01701	5.9e-178	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IMILKFDD_01702	3.98e-253	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IMILKFDD_01703	1.12e-72	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IMILKFDD_01704	1.41e-52	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IMILKFDD_01705	1.09e-243	-	-	-	C	-	-	-	FMN_bind
IMILKFDD_01706	2.26e-70	oxyR5	-	-	K	-	-	-	Transcriptional regulator
IMILKFDD_01707	2.85e-200	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IMILKFDD_01708	2.08e-249	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
IMILKFDD_01709	1.14e-92	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IMILKFDD_01710	6.41e-167	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
IMILKFDD_01711	6.89e-127	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IMILKFDD_01712	3.84e-105	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IMILKFDD_01713	5.3e-12	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
IMILKFDD_01714	9.91e-78	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
IMILKFDD_01715	7.06e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IMILKFDD_01717	4.09e-291	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMILKFDD_01718	3.46e-39	-	-	-	S	-	-	-	Belongs to the HesB IscA family
IMILKFDD_01719	3.65e-86	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
IMILKFDD_01721	1.77e-67	-	-	-	K	-	-	-	LysR substrate binding domain
IMILKFDD_01722	2.23e-150	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IMILKFDD_01723	2.09e-55	-	-	-	-	-	-	-	-
IMILKFDD_01724	2.4e-37	-	-	-	-	-	-	-	-
IMILKFDD_01725	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
IMILKFDD_01726	1.61e-64	-	-	-	-	-	-	-	-
IMILKFDD_01727	4.16e-136	-	-	-	-	-	-	-	-
IMILKFDD_01728	1.09e-68	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
IMILKFDD_01729	1.55e-70	-	-	-	-	-	-	-	-
IMILKFDD_01730	1.5e-150	-	-	-	-	-	-	-	-
IMILKFDD_01731	0.0	traE	-	-	U	-	-	-	AAA-like domain
IMILKFDD_01732	1.62e-288	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
IMILKFDD_01733	6.83e-263	-	-	-	M	-	-	-	CHAP domain
IMILKFDD_01734	4.74e-122	-	-	-	-	-	-	-	-
IMILKFDD_01735	1.14e-105	-	-	-	-	-	-	-	-
IMILKFDD_01736	0.0	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
IMILKFDD_01737	4.64e-83	-	-	-	-	-	-	-	-
IMILKFDD_01738	8.39e-196	-	-	-	-	-	-	-	-
IMILKFDD_01739	4.19e-87	-	-	-	-	-	-	-	-
IMILKFDD_01740	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IMILKFDD_01741	3.79e-26	-	-	-	-	-	-	-	-
IMILKFDD_01742	6.3e-107	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
IMILKFDD_01743	2.27e-125	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
IMILKFDD_01744	3.38e-93	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
IMILKFDD_01746	4.64e-23	-	-	-	-	-	-	-	-
IMILKFDD_01747	3.42e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
IMILKFDD_01748	3.37e-96	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IMILKFDD_01749	3.56e-31	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
IMILKFDD_01750	3.87e-114	-	-	-	-	-	-	-	-
IMILKFDD_01751	7.28e-132	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IMILKFDD_01752	1.65e-102	-	-	-	-	-	-	-	-
IMILKFDD_01753	3.86e-143	-	-	-	-	-	-	-	-
IMILKFDD_01754	6.74e-33	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IMILKFDD_01755	3.52e-62	-	-	-	-	-	-	-	-
IMILKFDD_01756	1.08e-83	-	-	-	-	-	-	-	-
IMILKFDD_01757	1.14e-188	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
IMILKFDD_01758	7.59e-48	-	-	-	-	-	-	-	-
IMILKFDD_01759	1.4e-174	repA	-	-	S	-	-	-	Replication initiator protein A
IMILKFDD_01760	4.7e-57	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
IMILKFDD_01761	4.89e-36	-	-	-	-	-	-	-	-
IMILKFDD_01762	6.58e-159	-	-	-	S	-	-	-	protein conserved in bacteria
IMILKFDD_01767	9.83e-30	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IMILKFDD_01771	8.8e-64	-	-	-	S	-	-	-	Fic/DOC family
IMILKFDD_01772	1.46e-261	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IMILKFDD_01773	5.21e-44	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
IMILKFDD_01775	8.69e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
IMILKFDD_01776	2.36e-14	-	-	-	D	-	-	-	nuclear chromosome segregation
IMILKFDD_01779	2.33e-90	-	-	-	DM	-	-	-	Glucan-binding protein C
IMILKFDD_01781	3.93e-131	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IMILKFDD_01782	1.83e-232	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IMILKFDD_01784	1.45e-56	-	-	-	L	-	-	-	PFAM HNH endonuclease
IMILKFDD_01788	1.76e-29	-	-	-	-	-	-	-	-
IMILKFDD_01791	6.74e-23	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
IMILKFDD_01802	5.71e-39	-	-	-	-	-	-	-	-
IMILKFDD_01803	1.56e-75	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
IMILKFDD_01810	1e-166	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IMILKFDD_01818	5.44e-50	-	-	-	-	-	-	-	-
IMILKFDD_01820	3.71e-56	-	-	-	T	-	-	-	phosphatase
IMILKFDD_01825	8.54e-43	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IMILKFDD_01834	3.41e-54	-	-	-	M	-	-	-	Prophage endopeptidase tail
IMILKFDD_01841	2.61e-43	-	-	-	O	-	-	-	ATP-dependent Clp protease ATP-binding subunit clpC
IMILKFDD_01845	2.55e-12	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
IMILKFDD_01847	1.61e-121	-	-	-	L	-	-	-	helicase
IMILKFDD_01850	3.8e-78	-	-	-	NU	-	-	-	StbA protein
IMILKFDD_01857	1.83e-20	-	-	-	-	-	-	-	-
IMILKFDD_01861	3.92e-162	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
IMILKFDD_01863	2.31e-187	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IMILKFDD_01864	1.16e-46	-	-	-	L	ko:K07496	-	ko00000	Helix-turn-helix domain
IMILKFDD_01866	1.84e-86	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
IMILKFDD_01867	3.25e-39	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
IMILKFDD_01868	1.3e-153	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
IMILKFDD_01875	5.02e-39	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
IMILKFDD_01876	1.16e-33	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
IMILKFDD_01882	7.11e-42	lytE	-	-	M	-	-	-	Lysin motif
IMILKFDD_01885	2.17e-19	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
IMILKFDD_01888	3.46e-139	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IMILKFDD_01889	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IMILKFDD_01890	1.5e-38	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
IMILKFDD_01891	1.47e-50	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
IMILKFDD_01892	2.01e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
IMILKFDD_01893	8.2e-10	-	-	-	S	-	-	-	Putative adhesin
IMILKFDD_01894	8.46e-23	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
IMILKFDD_01897	4.13e-296	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMILKFDD_01898	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
IMILKFDD_01899	3.27e-130	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IMILKFDD_01901	1.01e-34	-	-	-	S	-	-	-	Phage Mu protein F like protein
IMILKFDD_01902	2.16e-125	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
IMILKFDD_01903	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IMILKFDD_01905	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
IMILKFDD_01906	7.43e-91	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IMILKFDD_01910	8.17e-104	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
IMILKFDD_01911	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IMILKFDD_01913	1.66e-63	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IMILKFDD_01914	8.26e-62	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IMILKFDD_01922	3.14e-50	blpT	-	-	-	-	-	-	-
IMILKFDD_01923	1.94e-18	-	-	-	-	-	-	-	-
IMILKFDD_01925	1.9e-235	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IMILKFDD_01926	2.3e-103	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
IMILKFDD_01927	2.27e-86	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
IMILKFDD_01928	5.79e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IMILKFDD_01929	1.05e-143	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IMILKFDD_01930	4.48e-95	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
IMILKFDD_01931	1.02e-259	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMILKFDD_01932	2.19e-191	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IMILKFDD_01933	1.74e-80	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
IMILKFDD_01934	5.05e-115	nanK	-	-	GK	-	-	-	ROK family
IMILKFDD_01935	4.39e-162	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
IMILKFDD_01936	2.07e-117	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IMILKFDD_01937	2.77e-96	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IMILKFDD_01938	7.43e-80	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
IMILKFDD_01939	1.92e-270	potE	-	-	E	-	-	-	Amino Acid
IMILKFDD_01940	5.66e-08	-	-	-	-	-	-	-	-
IMILKFDD_01941	3.83e-43	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMILKFDD_01942	2.34e-288	fusA1	-	-	J	-	-	-	elongation factor G
IMILKFDD_01943	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMILKFDD_01944	1.38e-113	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMILKFDD_01945	7.62e-217	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
IMILKFDD_01946	1.37e-149	-	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
IMILKFDD_01947	1.46e-233	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IMILKFDD_01948	1.36e-47	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IMILKFDD_01949	2.62e-52	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IMILKFDD_01950	6.88e-78	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
IMILKFDD_01951	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IMILKFDD_01952	2.34e-37	-	-	-	L	-	-	-	PLD-like domain
IMILKFDD_01953	9.39e-69	-	-	-	L	-	-	-	PLD-like domain
IMILKFDD_01956	3.24e-142	-	-	-	L	-	-	-	Initiator Replication protein
IMILKFDD_01957	2.12e-48	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
IMILKFDD_01958	1.76e-210	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IMILKFDD_01959	8.54e-107	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	.Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome down-regulated in Spo0A mutant
IMILKFDD_01960	3.71e-21	bglG	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
IMILKFDD_01961	3.22e-161	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
IMILKFDD_01963	6.32e-47	-	-	-	-	-	-	-	-
IMILKFDD_01964	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IMILKFDD_01965	2.08e-53	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
IMILKFDD_01966	2.78e-23	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IMILKFDD_01971	3.26e-22	-	-	-	-	-	-	-	-
IMILKFDD_01972	4.41e-13	-	-	-	-	-	-	-	-
IMILKFDD_01974	1.78e-158	yvgN	-	-	C	-	-	-	Aldo keto reductase
IMILKFDD_01975	9.58e-132	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
IMILKFDD_01976	1.06e-34	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
IMILKFDD_01977	2.11e-32	-	-	-	S	-	-	-	Sulphur transport
IMILKFDD_01978	7.13e-16	-	-	-	O	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IMILKFDD_01979	3.18e-146	-	-	-	P	-	-	-	Rhodanese Homology Domain
IMILKFDD_01981	1.68e-291	prdA	1.21.4.1	-	EJ	ko:K10793	ko00330,map00330	ko00000,ko00001,ko01000	Glycine/sarcosine/betaine reductase component B subunits
IMILKFDD_01982	4.5e-34	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IMILKFDD_01983	1.14e-84	prdB	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a premature stop
IMILKFDD_01984	2.69e-42	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a premature stop
IMILKFDD_01985	1.19e-91	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
IMILKFDD_01986	6.97e-87	-	-	-	EJ	-	-	-	Glycine/sarcosine/betaine reductase component B subunits
IMILKFDD_01987	2.12e-182	-	5.1.1.4	-	E	ko:K01777	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Proline racemase
IMILKFDD_01988	2.77e-123	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
IMILKFDD_01989	1.53e-280	-	-	-	E	-	-	-	amino acid
IMILKFDD_01990	2.85e-60	yedF	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
IMILKFDD_01992	1.69e-169	selB	-	-	J	ko:K03833	-	ko00000,ko03012	Elongation factor SelB, winged helix
IMILKFDD_01993	1.58e-136	-	-	-	E	-	-	-	Serine hydroxymethyltransferase
IMILKFDD_01994	1.21e-142	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
IMILKFDD_01995	7.55e-38	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IMILKFDD_01996	3.81e-236	-	-	-	C	-	-	-	RnfC Barrel sandwich hybrid domain
IMILKFDD_01997	2.9e-125	selD	2.7.9.3	-	E	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	Synthesizes selenophosphate from selenide and ATP
IMILKFDD_01998	1.31e-187	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
IMILKFDD_01999	4.23e-38	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
IMILKFDD_02000	7.11e-15	-	-	-	GKT	-	-	-	COG3711 Transcriptional antiterminator
IMILKFDD_02001	5.14e-75	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
IMILKFDD_02002	3.31e-231	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
IMILKFDD_02003	8.39e-62	-	-	-	S	-	-	-	Membrane
IMILKFDD_02004	1.8e-94	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IMILKFDD_02005	1.26e-97	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
IMILKFDD_02006	1.9e-98	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
IMILKFDD_02007	1.26e-272	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IMILKFDD_02008	8.21e-53	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
IMILKFDD_02009	6e-258	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
IMILKFDD_02010	1.3e-140	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
IMILKFDD_02012	9.27e-74	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IMILKFDD_02013	2.77e-143	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IMILKFDD_02015	1.63e-135	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IMILKFDD_02017	1.22e-61	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IMILKFDD_02019	7.6e-203	-	-	-	L	-	-	-	T/G mismatch-specific endonuclease activity
IMILKFDD_02020	1.09e-78	-	-	-	-	-	-	-	-
IMILKFDD_02021	5.65e-82	-	-	-	-	-	-	-	-
IMILKFDD_02022	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
IMILKFDD_02023	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
IMILKFDD_02024	6.5e-114	yeeC	-	-	P	-	-	-	T5orf172
IMILKFDD_02026	3.95e-16	-	-	-	-	-	-	-	-
IMILKFDD_02029	3.35e-216	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
IMILKFDD_02030	2.23e-184	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
IMILKFDD_02031	1.11e-147	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IMILKFDD_02032	1.61e-75	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IMILKFDD_02033	2.66e-101	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
IMILKFDD_02034	3.77e-57	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IMILKFDD_02036	1.73e-49	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IMILKFDD_02037	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IMILKFDD_02038	1.23e-34	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
IMILKFDD_02039	3.22e-140	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
IMILKFDD_02041	2.14e-67	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
IMILKFDD_02042	6.14e-76	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IMILKFDD_02043	1.39e-195	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IMILKFDD_02044	2.08e-120	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
IMILKFDD_02045	8.3e-160	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
IMILKFDD_02046	2.58e-53	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
IMILKFDD_02047	1.98e-34	-	-	-	L	ko:K07498	-	ko00000	Transposase
IMILKFDD_02048	1.32e-33	-	-	-	L	ko:K07498	-	ko00000	Transposase
IMILKFDD_02049	3.43e-45	-	-	-	P	-	-	-	Heavy-metal-associated domain
IMILKFDD_02050	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
IMILKFDD_02051	1.09e-25	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
IMILKFDD_02052	5.92e-101	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
IMILKFDD_02053	3.78e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IMILKFDD_02054	8.06e-122	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IMILKFDD_02055	6.03e-88	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
IMILKFDD_02056	7.4e-177	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
IMILKFDD_02057	1.73e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IMILKFDD_02058	2.95e-271	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IMILKFDD_02059	5.13e-176	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMILKFDD_02060	4.79e-89	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IMILKFDD_02061	1.8e-180	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
IMILKFDD_02065	3.79e-113	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IMILKFDD_02066	1.06e-13	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IMILKFDD_02067	2.12e-48	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IMILKFDD_02068	2.37e-97	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
IMILKFDD_02069	6.11e-73	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IMILKFDD_02070	1.94e-67	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IMILKFDD_02071	8.46e-101	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IMILKFDD_02072	1.15e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IMILKFDD_02073	5e-100	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IMILKFDD_02074	1.42e-34	-	-	-	-	-	-	-	-
IMILKFDD_02075	3.76e-18	-	-	-	-	-	-	-	-
IMILKFDD_02076	2.15e-141	rssA	-	-	S	-	-	-	Phospholipase, patatin family
IMILKFDD_02077	5.49e-175	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMILKFDD_02078	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
IMILKFDD_02079	6.68e-64	-	-	-	S	-	-	-	VIT family
IMILKFDD_02080	1.66e-72	-	-	-	L	ko:K07487	-	ko00000	Transposase DDE domain
IMILKFDD_02081	9.19e-304	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IMILKFDD_02082	1.9e-52	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IMILKFDD_02083	5.64e-182	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMILKFDD_02084	4.96e-178	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
IMILKFDD_02085	1.5e-147	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IMILKFDD_02086	3.47e-278	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IMILKFDD_02087	2.3e-174	-	-	-	P	-	-	-	Voltage gated chloride channel
IMILKFDD_02088	5.44e-36	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IMILKFDD_02089	5.44e-173	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IMILKFDD_02090	9.61e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IMILKFDD_02091	1.01e-83	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
IMILKFDD_02092	1.28e-46	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
IMILKFDD_02093	8.56e-173	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
IMILKFDD_02094	4.75e-107	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
IMILKFDD_02095	9.94e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
IMILKFDD_02096	1.41e-93	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
IMILKFDD_02097	8.3e-142	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
IMILKFDD_02098	3.46e-34	-	-	-	M	-	-	-	by MetaGeneAnnotator
IMILKFDD_02099	2e-46	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
IMILKFDD_02101	1.04e-07	-	-	-	S	-	-	-	Phage minor structural protein GP20
IMILKFDD_02103	2.06e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
IMILKFDD_02108	9.84e-38	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
IMILKFDD_02112	8.65e-27	-	-	-	-	-	-	-	-
IMILKFDD_02113	3.19e-208	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
IMILKFDD_02114	7.66e-177	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
IMILKFDD_02115	1.37e-112	-	-	-	S	-	-	-	Phage minor capsid protein 2
IMILKFDD_02117	2.36e-25	-	-	-	S	-	-	-	Phage minor structural protein GP20
IMILKFDD_02118	2.89e-123	-	-	-	S	-	-	-	T=7 icosahedral viral capsid
IMILKFDD_02120	1.86e-39	-	-	-	S	-	-	-	Minor capsid protein
IMILKFDD_02123	4.29e-49	-	-	-	N	-	-	-	domain, Protein
IMILKFDD_02125	5.5e-50	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
IMILKFDD_02126	1.36e-114	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
IMILKFDD_02129	1.64e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
IMILKFDD_02130	1.65e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
IMILKFDD_02133	7.35e-07	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
IMILKFDD_02135	1.24e-08	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IMILKFDD_02147	4.35e-36	-	-	-	E	-	-	-	Zn peptidase
IMILKFDD_02149	1.2e-73	repB	-	-	L	-	-	-	Initiator Replication protein
IMILKFDD_02150	2.56e-121	-	-	-	L	-	-	-	Probable transposase
IMILKFDD_02151	1.6e-78	-	-	-	L	-	-	-	Resolvase, N-terminal domain
IMILKFDD_02152	1.28e-211	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IMILKFDD_02153	3.16e-152	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IMILKFDD_02154	3.11e-133	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IMILKFDD_02155	7.13e-201	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IMILKFDD_02156	7.9e-169	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IMILKFDD_02157	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IMILKFDD_02158	1.41e-138	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IMILKFDD_02159	2.89e-86	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IMILKFDD_02160	6.58e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IMILKFDD_02161	8.71e-286	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IMILKFDD_02162	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IMILKFDD_02163	2.22e-131	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
IMILKFDD_02164	1.13e-69	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IMILKFDD_02165	5.18e-61	-	-	-	C	-	-	-	Flavodoxin
IMILKFDD_02166	6.28e-71	yphH	-	-	S	-	-	-	Cupin domain
IMILKFDD_02167	6.97e-58	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
IMILKFDD_02168	3.1e-178	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IMILKFDD_02169	1.72e-134	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IMILKFDD_02170	1.87e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMILKFDD_02171	6.39e-120	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IMILKFDD_02172	1.85e-167	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IMILKFDD_02173	2.84e-107	-	-	-	C	-	-	-	nitroreductase
IMILKFDD_02174	5.36e-107	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
IMILKFDD_02175	1.16e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
IMILKFDD_02176	6.07e-214	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IMILKFDD_02177	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
IMILKFDD_02178	1.6e-83	-	-	-	S	-	-	-	Putative HNHc nuclease
IMILKFDD_02179	5.6e-37	-	-	-	S	-	-	-	calcium ion binding
IMILKFDD_02180	3.19e-157	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
IMILKFDD_02183	1.18e-30	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
IMILKFDD_02185	1.48e-157	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
IMILKFDD_02186	2.79e-47	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
IMILKFDD_02187	6.71e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IMILKFDD_02188	1.69e-85	-	-	-	S	-	-	-	Putative HNHc nuclease
IMILKFDD_02191	4.51e-107	-	-	-	M	-	-	-	domain, Protein
IMILKFDD_02193	1.53e-192	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMILKFDD_02194	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IMILKFDD_02195	3.63e-163	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IMILKFDD_02196	5.71e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
IMILKFDD_02198	7.07e-122	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IMILKFDD_02199	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IMILKFDD_02200	1.63e-267	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IMILKFDD_02201	1.49e-223	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IMILKFDD_02202	7.47e-213	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
IMILKFDD_02203	6.36e-229	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IMILKFDD_02204	4.36e-291	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
IMILKFDD_02205	6.7e-187	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IMILKFDD_02206	9.24e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IMILKFDD_02207	4.91e-79	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IMILKFDD_02208	2.52e-17	-	-	-	-	-	-	-	-
IMILKFDD_02209	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IMILKFDD_02210	1.13e-280	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IMILKFDD_02211	1.39e-111	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
IMILKFDD_02212	3.31e-192	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IMILKFDD_02213	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
IMILKFDD_02216	3.16e-19	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
IMILKFDD_02217	1.07e-157	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IMILKFDD_02218	4.45e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
IMILKFDD_02219	6.95e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
IMILKFDD_02220	1.85e-62	-	-	-	S	-	-	-	AAA domain