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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
CIPFEANN_00001	0.0	-	-	-	L	-	-	-	PLD-like domain
CIPFEANN_00002	3.73e-62	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
CIPFEANN_00006	1.04e-101	-	-	-	S	ko:K17882	-	ko00000,ko01000,ko01504	KNTase C-terminal domain
CIPFEANN_00007	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
CIPFEANN_00008	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
CIPFEANN_00009	2.9e-120	dpsB	-	-	P	-	-	-	Belongs to the Dps family
CIPFEANN_00010	9.73e-146	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
CIPFEANN_00012	3.29e-58	mob	-	-	D	-	-	-	Plasmid recombination enzyme
CIPFEANN_00013	6.04e-06	-	-	-	S	-	-	-	Plasmid replication protein
CIPFEANN_00014	7.04e-30	-	-	-	K	-	-	-	sequence-specific DNA binding
CIPFEANN_00015	0.0	-	-	-	J	-	-	-	Elongation factor G, domain IV
CIPFEANN_00016	3.67e-255	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
CIPFEANN_00017	5.36e-97	-	-	-	-	-	-	-	-
CIPFEANN_00018	9.29e-290	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CIPFEANN_00019	7.41e-163	-	-	-	-	-	-	-	-
CIPFEANN_00020	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
CIPFEANN_00021	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
CIPFEANN_00023	3.04e-259	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CIPFEANN_00024	5.29e-163	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CIPFEANN_00026	7.45e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
CIPFEANN_00027	7.22e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CIPFEANN_00028	4.61e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CIPFEANN_00029	3.8e-196	-	-	-	EG	-	-	-	EamA-like transporter family
CIPFEANN_00030	9.45e-152	-	-	-	L	-	-	-	Integrase
CIPFEANN_00031	8.45e-203	rssA	-	-	S	-	-	-	Phospholipase, patatin family
CIPFEANN_00032	4.61e-123	-	-	-	M	-	-	-	domain protein
CIPFEANN_00033	9.23e-138	-	-	-	-	-	-	-	-
CIPFEANN_00035	1.09e-200	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CIPFEANN_00036	1.24e-92	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CIPFEANN_00038	2.13e-74	-	-	-	-	-	-	-	-
CIPFEANN_00040	2.05e-109	-	-	-	-	-	-	-	-
CIPFEANN_00041	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
CIPFEANN_00042	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
CIPFEANN_00043	1.6e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
CIPFEANN_00044	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
CIPFEANN_00045	1.29e-205	-	-	-	EG	-	-	-	EamA-like transporter family
CIPFEANN_00046	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
CIPFEANN_00047	3.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CIPFEANN_00048	3.05e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
CIPFEANN_00049	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
CIPFEANN_00050	8.24e-251	xylR	-	-	GK	-	-	-	ROK family
CIPFEANN_00051	2.49e-39	-	-	-	-	-	-	-	-
CIPFEANN_00052	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
CIPFEANN_00053	6.42e-140	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
CIPFEANN_00054	1.57e-199	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
CIPFEANN_00055	0.0	yclK	-	-	T	-	-	-	Histidine kinase
CIPFEANN_00056	2.7e-172	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
CIPFEANN_00058	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
CIPFEANN_00059	4.01e-193	-	-	-	S	-	-	-	Cof-like hydrolase
CIPFEANN_00060	3.7e-106	-	-	-	K	-	-	-	Transcriptional regulator
CIPFEANN_00061	0.0	oatA	-	-	I	-	-	-	Acyltransferase
CIPFEANN_00062	5.17e-70	-	-	-	-	-	-	-	-
CIPFEANN_00063	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CIPFEANN_00064	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CIPFEANN_00065	6.13e-164	ybbR	-	-	S	-	-	-	YbbR-like protein
CIPFEANN_00066	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CIPFEANN_00067	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
CIPFEANN_00068	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CIPFEANN_00069	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIPFEANN_00070	2.76e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
CIPFEANN_00071	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CIPFEANN_00072	3.55e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
CIPFEANN_00073	1.46e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CIPFEANN_00074	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
CIPFEANN_00075	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
CIPFEANN_00076	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CIPFEANN_00077	9.61e-137	-	-	-	-	-	-	-	-
CIPFEANN_00078	3.15e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CIPFEANN_00079	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CIPFEANN_00080	3.29e-187	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
CIPFEANN_00081	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CIPFEANN_00082	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CIPFEANN_00084	6.71e-206	-	-	-	S	-	-	-	reductase
CIPFEANN_00085	2.02e-69	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
CIPFEANN_00086	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CIPFEANN_00087	1.13e-301	-	-	-	L	-	-	-	Helicase C-terminal domain protein
CIPFEANN_00089	2.05e-20	-	-	-	L	-	-	-	PFAM Integrase catalytic region
CIPFEANN_00090	4.9e-202	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
CIPFEANN_00091	3.74e-213	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
CIPFEANN_00092	2.01e-29	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CIPFEANN_00093	3.81e-52	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
CIPFEANN_00094	4.36e-287	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
CIPFEANN_00095	1.62e-157	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
CIPFEANN_00096	4.01e-216	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CIPFEANN_00097	3.35e-59	-	-	-	S	-	-	-	Pfam:DUF59
CIPFEANN_00098	4.48e-90	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CIPFEANN_00099	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
CIPFEANN_00100	1.03e-37	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
CIPFEANN_00103	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
CIPFEANN_00104	4.85e-136	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CIPFEANN_00105	8.04e-115	-	-	-	S	-	-	-	Acyltransferase family
CIPFEANN_00107	1.69e-183	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
CIPFEANN_00108	3.38e-102	-	-	-	L	-	-	-	helicase activity
CIPFEANN_00110	1.03e-72	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIPFEANN_00112	4.36e-297	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CIPFEANN_00113	1.13e-123	-	-	-	G	-	-	-	Right handed beta helix region
CIPFEANN_00114	1.61e-45	-	-	-	G	-	-	-	Right handed beta helix region
CIPFEANN_00115	6.08e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIPFEANN_00116	6.21e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
CIPFEANN_00117	1.51e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
CIPFEANN_00118	2.71e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIPFEANN_00119	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
CIPFEANN_00120	1.06e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
CIPFEANN_00121	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CIPFEANN_00122	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CIPFEANN_00123	8.02e-159	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
CIPFEANN_00124	4.84e-241	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
CIPFEANN_00125	2.4e-212	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
CIPFEANN_00126	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CIPFEANN_00127	2.88e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIPFEANN_00128	1.23e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
CIPFEANN_00129	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIPFEANN_00130	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
CIPFEANN_00131	1.88e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CIPFEANN_00132	1.54e-269	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CIPFEANN_00133	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
CIPFEANN_00134	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
CIPFEANN_00135	2.75e-309	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
CIPFEANN_00136	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
CIPFEANN_00137	2.7e-145	-	-	-	S	-	-	-	(CBS) domain
CIPFEANN_00138	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CIPFEANN_00139	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CIPFEANN_00140	1.18e-51	yabO	-	-	J	-	-	-	S4 domain protein
CIPFEANN_00141	7.15e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
CIPFEANN_00142	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
CIPFEANN_00143	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CIPFEANN_00144	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
CIPFEANN_00145	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIPFEANN_00146	7.93e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CIPFEANN_00147	1.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CIPFEANN_00148	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
CIPFEANN_00149	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
CIPFEANN_00150	1.6e-272	-	-	-	L	-	-	-	Integrase core domain
CIPFEANN_00151	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
CIPFEANN_00171	1.74e-21	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
CIPFEANN_00172	1.03e-167	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
CIPFEANN_00173	8.56e-90	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIPFEANN_00174	4.85e-245	isp	-	-	L	-	-	-	Transposase
CIPFEANN_00175	3.55e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
CIPFEANN_00176	6.14e-71	-	-	-	-	-	-	-	-
CIPFEANN_00177	5.9e-48	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
CIPFEANN_00178	5.28e-29	-	-	-	-	-	-	-	-
CIPFEANN_00179	8.9e-169	-	-	-	L	-	-	-	Transposase
CIPFEANN_00180	1.65e-112	isp	-	-	L	-	-	-	Transposase
CIPFEANN_00181	5.21e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIPFEANN_00182	2.4e-162	-	-	-	EGP	-	-	-	Major Facilitator
CIPFEANN_00183	6.65e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
CIPFEANN_00184	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
CIPFEANN_00185	1.73e-148	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
CIPFEANN_00186	4.11e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CIPFEANN_00187	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CIPFEANN_00188	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CIPFEANN_00189	2.11e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
CIPFEANN_00190	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
CIPFEANN_00191	3.67e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CIPFEANN_00192	3.31e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CIPFEANN_00193	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
CIPFEANN_00194	1.79e-214	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
CIPFEANN_00195	5.04e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
CIPFEANN_00196	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
CIPFEANN_00197	2.03e-208	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
CIPFEANN_00198	1.35e-215	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CIPFEANN_00199	2.21e-276	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CIPFEANN_00200	1.36e-116	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
CIPFEANN_00201	5.46e-62	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
CIPFEANN_00202	2.85e-114	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
CIPFEANN_00203	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CIPFEANN_00204	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
CIPFEANN_00205	4.16e-19	-	-	-	-	-	-	-	-
CIPFEANN_00206	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CIPFEANN_00207	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CIPFEANN_00208	5.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
CIPFEANN_00209	8.05e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
CIPFEANN_00210	5.73e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
CIPFEANN_00211	1.94e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
CIPFEANN_00213	1.83e-21	-	-	-	-	-	-	-	-
CIPFEANN_00214	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CIPFEANN_00216	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CIPFEANN_00217	1.08e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
CIPFEANN_00218	1.45e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIPFEANN_00219	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CIPFEANN_00220	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
CIPFEANN_00221	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
CIPFEANN_00222	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
CIPFEANN_00223	3.11e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
CIPFEANN_00224	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
CIPFEANN_00226	5.9e-82	-	-	-	S	ko:K19279	-	ko00000,ko01000,ko01504	Domain of unknown function (DUF4111)
CIPFEANN_00227	2.95e-41	-	-	-	S	ko:K19279	-	ko00000,ko01000,ko01504	Domain of unknown function (DUF4111)
CIPFEANN_00228	6.31e-07	-	-	-	S	-	-	-	similarity to EGAD 6135
CIPFEANN_00229	1.06e-131	-	-	-	EGP	-	-	-	Major Facilitator
CIPFEANN_00230	8.81e-89	-	-	-	K	-	-	-	Transcriptional regulator
CIPFEANN_00232	2.84e-31	-	-	-	-	-	-	-	-
CIPFEANN_00233	4.95e-40	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CIPFEANN_00235	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
CIPFEANN_00236	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CIPFEANN_00237	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CIPFEANN_00238	1.51e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CIPFEANN_00239	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CIPFEANN_00240	1.25e-241	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CIPFEANN_00241	7.54e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CIPFEANN_00242	6.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
CIPFEANN_00243	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CIPFEANN_00244	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CIPFEANN_00245	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
CIPFEANN_00246	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CIPFEANN_00247	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
CIPFEANN_00248	2.4e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
CIPFEANN_00249	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CIPFEANN_00250	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CIPFEANN_00251	1.01e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
CIPFEANN_00252	2.58e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
CIPFEANN_00253	3.33e-133	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CIPFEANN_00254	9.81e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
CIPFEANN_00255	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
CIPFEANN_00256	1.1e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
CIPFEANN_00257	6.23e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
CIPFEANN_00258	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CIPFEANN_00259	1.84e-75	-	-	-	-	-	-	-	-
CIPFEANN_00260	1.08e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CIPFEANN_00261	1.63e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
CIPFEANN_00262	6.66e-178	-	-	-	-	-	-	-	-
CIPFEANN_00263	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
CIPFEANN_00264	4.67e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
CIPFEANN_00265	2.49e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
CIPFEANN_00266	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
CIPFEANN_00267	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
CIPFEANN_00268	1.61e-54	-	-	-	-	-	-	-	-
CIPFEANN_00269	9.32e-92	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
CIPFEANN_00271	2.07e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
CIPFEANN_00272	5.93e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIPFEANN_00273	1.08e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CIPFEANN_00274	9.28e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
CIPFEANN_00275	2.87e-171	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CIPFEANN_00276	5.97e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
CIPFEANN_00277	1.83e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
CIPFEANN_00278	2.49e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
CIPFEANN_00279	7.52e-65	-	-	-	-	-	-	-	-
CIPFEANN_00280	7.52e-242	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
CIPFEANN_00281	4.22e-140	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
CIPFEANN_00282	1.85e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
CIPFEANN_00283	1.99e-73	ymcC	-	-	S	-	-	-	Membrane
CIPFEANN_00285	3.36e-131	-	-	-	L	-	-	-	Transposase
CIPFEANN_00286	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CIPFEANN_00288	2.24e-205	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CIPFEANN_00289	1.91e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
CIPFEANN_00290	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
CIPFEANN_00291	1.26e-96	-	-	-	K	-	-	-	MerR HTH family regulatory protein
CIPFEANN_00292	9.15e-72	-	-	-	-	-	-	-	-
CIPFEANN_00293	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIPFEANN_00294	8.69e-277	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CIPFEANN_00295	2.11e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIPFEANN_00296	1.06e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIPFEANN_00297	3.85e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIPFEANN_00298	8.01e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_00299	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
CIPFEANN_00300	2.34e-142	-	-	-	S	-	-	-	VIT family
CIPFEANN_00301	7.33e-152	-	-	-	S	-	-	-	membrane
CIPFEANN_00302	2.85e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
CIPFEANN_00303	9.44e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
CIPFEANN_00304	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CIPFEANN_00305	4.05e-164	-	-	-	S	-	-	-	Putative threonine/serine exporter
CIPFEANN_00306	5.02e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
CIPFEANN_00307	2.79e-153	-	-	-	I	-	-	-	phosphatase
CIPFEANN_00309	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
CIPFEANN_00310	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
CIPFEANN_00316	3.58e-168	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
CIPFEANN_00317	4.62e-21	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
CIPFEANN_00318	8.94e-250	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
CIPFEANN_00319	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
CIPFEANN_00320	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CIPFEANN_00321	4.92e-142	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIPFEANN_00322	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIPFEANN_00323	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIPFEANN_00324	3.13e-61	-	-	-	-	-	-	-	-
CIPFEANN_00325	2.05e-20	-	-	-	L	-	-	-	PFAM Integrase catalytic region
CIPFEANN_00326	2.25e-99	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
CIPFEANN_00327	3.44e-12	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
CIPFEANN_00329	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CIPFEANN_00330	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
CIPFEANN_00331	1.76e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
CIPFEANN_00332	1.76e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
CIPFEANN_00333	3.15e-153	dltr	-	-	K	-	-	-	response regulator
CIPFEANN_00334	1.13e-289	sptS	-	-	T	-	-	-	Histidine kinase
CIPFEANN_00335	1.41e-265	-	-	-	P	-	-	-	Voltage gated chloride channel
CIPFEANN_00336	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
CIPFEANN_00337	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
CIPFEANN_00338	2.1e-214	-	-	-	C	-	-	-	Aldo keto reductase
CIPFEANN_00339	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
CIPFEANN_00340	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
CIPFEANN_00341	7.6e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
CIPFEANN_00342	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
CIPFEANN_00343	6.39e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIPFEANN_00344	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CIPFEANN_00345	1.98e-118	-	-	-	-	-	-	-	-
CIPFEANN_00346	4.65e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CIPFEANN_00348	3.25e-18	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
CIPFEANN_00349	5.88e-64	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
CIPFEANN_00350	8.53e-95	-	-	-	-	-	-	-	-
CIPFEANN_00351	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CIPFEANN_00352	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
CIPFEANN_00353	0.0	-	-	-	M	-	-	-	domain protein
CIPFEANN_00354	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CIPFEANN_00355	8.94e-11	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CIPFEANN_00356	1.42e-309	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CIPFEANN_00357	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CIPFEANN_00358	1.83e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CIPFEANN_00359	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CIPFEANN_00360	2.93e-168	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
CIPFEANN_00361	5.12e-266	yacL	-	-	S	-	-	-	domain protein
CIPFEANN_00362	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CIPFEANN_00363	1.1e-125	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
CIPFEANN_00364	3.33e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
CIPFEANN_00365	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CIPFEANN_00366	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CIPFEANN_00367	3.51e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
CIPFEANN_00368	2.38e-171	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_00369	9.62e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIPFEANN_00370	2.47e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
CIPFEANN_00371	6.27e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CIPFEANN_00372	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIPFEANN_00373	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
CIPFEANN_00374	3.18e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
CIPFEANN_00375	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
CIPFEANN_00377	5.75e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
CIPFEANN_00378	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
CIPFEANN_00379	6.42e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CIPFEANN_00380	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIPFEANN_00381	1.44e-164	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
CIPFEANN_00382	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
CIPFEANN_00383	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
CIPFEANN_00384	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CIPFEANN_00385	8.98e-143	-	-	-	-	-	-	-	-
CIPFEANN_00388	1.52e-201	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CIPFEANN_00389	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
CIPFEANN_00392	2.12e-112	-	-	-	C	-	-	-	Oxidoreductase
CIPFEANN_00393	3.41e-27	-	-	-	C	-	-	-	Oxidoreductase
CIPFEANN_00394	2.89e-68	-	-	-	C	-	-	-	Oxidoreductase
CIPFEANN_00395	3.88e-71	-	-	-	S	-	-	-	macrophage migration inhibitory factor
CIPFEANN_00396	4.95e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
CIPFEANN_00397	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CIPFEANN_00399	4e-243	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
CIPFEANN_00400	2.79e-179	-	-	-	K	-	-	-	LysR substrate binding domain
CIPFEANN_00401	6.04e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
CIPFEANN_00402	5.23e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CIPFEANN_00403	1.6e-219	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CIPFEANN_00404	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CIPFEANN_00405	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CIPFEANN_00406	1.91e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
CIPFEANN_00407	5.29e-122	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CIPFEANN_00408	1.15e-301	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
CIPFEANN_00409	3.91e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
CIPFEANN_00410	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
CIPFEANN_00411	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
CIPFEANN_00412	9.77e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
CIPFEANN_00413	3.65e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CIPFEANN_00414	1.61e-271	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CIPFEANN_00415	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CIPFEANN_00416	2.13e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
CIPFEANN_00417	2.23e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIPFEANN_00418	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIPFEANN_00419	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIPFEANN_00420	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CIPFEANN_00421	5.37e-248	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
CIPFEANN_00422	8.26e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CIPFEANN_00423	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
CIPFEANN_00424	4.57e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
CIPFEANN_00425	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIPFEANN_00426	7.38e-232	-	-	-	-	-	-	-	-
CIPFEANN_00427	4.92e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CIPFEANN_00428	5.54e-105	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
CIPFEANN_00434	1.08e-177	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
CIPFEANN_00437	7.55e-178	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
CIPFEANN_00438	7.99e-61	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
CIPFEANN_00439	8.76e-13	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
CIPFEANN_00442	1.66e-19	-	-	-	K	-	-	-	ORF6N domain
CIPFEANN_00443	3.85e-31	XK27_00515	-	-	D	-	-	-	Glucan-binding protein C
CIPFEANN_00446	6.83e-116	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIPFEANN_00447	9.08e-40	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
CIPFEANN_00448	2.21e-182	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system methyltransferase subunit()
CIPFEANN_00450	1.05e-91	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIPFEANN_00451	4.38e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CIPFEANN_00452	2.08e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
CIPFEANN_00453	1.09e-227	-	-	-	-	-	-	-	-
CIPFEANN_00454	1.02e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
CIPFEANN_00456	4.74e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
CIPFEANN_00457	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIPFEANN_00458	5.3e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
CIPFEANN_00459	6.03e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CIPFEANN_00460	9.83e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CIPFEANN_00461	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
CIPFEANN_00462	5.5e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CIPFEANN_00463	1.66e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CIPFEANN_00464	2.31e-156	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CIPFEANN_00465	4.12e-164	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
CIPFEANN_00466	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
CIPFEANN_00467	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CIPFEANN_00468	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIPFEANN_00469	1.6e-100	-	-	-	-	-	-	-	-
CIPFEANN_00470	1.89e-189	yidA	-	-	S	-	-	-	hydrolase
CIPFEANN_00471	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
CIPFEANN_00472	4.82e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
CIPFEANN_00473	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
CIPFEANN_00474	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CIPFEANN_00475	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CIPFEANN_00476	5.29e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIPFEANN_00477	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
CIPFEANN_00478	2.64e-302	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIPFEANN_00479	1.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CIPFEANN_00480	4.29e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
CIPFEANN_00481	1.99e-123	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CIPFEANN_00482	3.46e-09	-	-	-	EG	-	-	-	EamA-like transporter family
CIPFEANN_00483	4.28e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
CIPFEANN_00484	4.06e-103	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
CIPFEANN_00485	3.85e-24	-	-	-	S	-	-	-	PFAM Archaeal ATPase
CIPFEANN_00487	1.86e-227	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIPFEANN_00488	1.64e-23	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
CIPFEANN_00489	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_00490	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CIPFEANN_00491	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
CIPFEANN_00492	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CIPFEANN_00493	9.16e-111	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CIPFEANN_00494	3.02e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
CIPFEANN_00495	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
CIPFEANN_00496	1.05e-310	-	-	-	E	-	-	-	amino acid
CIPFEANN_00497	2.6e-179	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
CIPFEANN_00498	9.75e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CIPFEANN_00499	2.17e-213	-	-	-	GK	-	-	-	ROK family
CIPFEANN_00500	0.0	fusA1	-	-	J	-	-	-	elongation factor G
CIPFEANN_00501	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
CIPFEANN_00502	1.42e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
CIPFEANN_00503	1.78e-83	-	-	-	-	-	-	-	-
CIPFEANN_00504	3.18e-11	-	-	-	-	-	-	-	-
CIPFEANN_00505	6.79e-271	-	-	-	EGP	-	-	-	Major Facilitator
CIPFEANN_00506	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
CIPFEANN_00507	6.23e-152	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
CIPFEANN_00508	2.74e-62	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
CIPFEANN_00509	3.46e-207	-	-	-	-	-	-	-	-
CIPFEANN_00510	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
CIPFEANN_00511	2.53e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
CIPFEANN_00512	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
CIPFEANN_00513	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CIPFEANN_00514	6.5e-71	-	-	-	-	-	-	-	-
CIPFEANN_00515	2.91e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CIPFEANN_00516	4.68e-314	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_00517	8.59e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
CIPFEANN_00518	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CIPFEANN_00519	7.72e-178	-	-	-	IQ	-	-	-	KR domain
CIPFEANN_00520	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
CIPFEANN_00521	9.79e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
CIPFEANN_00522	1.74e-194	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CIPFEANN_00523	7.67e-162	-	-	-	L	-	-	-	Helix-turn-helix domain
CIPFEANN_00524	1.86e-62	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
CIPFEANN_00525	9.45e-152	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
CIPFEANN_00526	0.0	yagE	-	-	E	-	-	-	amino acid
CIPFEANN_00527	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
CIPFEANN_00528	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
CIPFEANN_00529	8.65e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CIPFEANN_00530	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CIPFEANN_00531	2.07e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CIPFEANN_00532	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIPFEANN_00533	4.43e-183	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIPFEANN_00534	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIPFEANN_00535	1.97e-293	-	-	-	-	-	-	-	-
CIPFEANN_00536	5.91e-297	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
CIPFEANN_00537	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
CIPFEANN_00538	3.59e-97	-	-	-	F	-	-	-	Nudix hydrolase
CIPFEANN_00539	2.75e-132	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
CIPFEANN_00540	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
CIPFEANN_00541	6.02e-34	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
CIPFEANN_00542	4.65e-193	-	-	-	-	-	-	-	-
CIPFEANN_00543	8.65e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
CIPFEANN_00544	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
CIPFEANN_00545	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
CIPFEANN_00546	3.17e-233	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIPFEANN_00547	6.08e-13	-	-	-	S	-	-	-	CsbD-like
CIPFEANN_00548	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
CIPFEANN_00549	1.27e-291	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CIPFEANN_00550	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
CIPFEANN_00551	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
CIPFEANN_00552	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CIPFEANN_00553	1.26e-44	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
CIPFEANN_00554	1.77e-202	-	-	-	EG	-	-	-	EamA-like transporter family
CIPFEANN_00555	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CIPFEANN_00556	5.62e-224	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
CIPFEANN_00557	7.02e-288	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
CIPFEANN_00559	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
CIPFEANN_00560	1.53e-25	-	-	-	-	-	-	-	-
CIPFEANN_00561	6.22e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
CIPFEANN_00562	3.85e-72	-	-	-	-	-	-	-	-
CIPFEANN_00563	6.51e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
CIPFEANN_00564	6.77e-306	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
CIPFEANN_00565	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CIPFEANN_00566	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
CIPFEANN_00567	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CIPFEANN_00568	9.42e-111	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CIPFEANN_00569	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
CIPFEANN_00570	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIPFEANN_00571	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIPFEANN_00572	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CIPFEANN_00573	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
CIPFEANN_00574	9.78e-14	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
CIPFEANN_00575	1.97e-105	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
CIPFEANN_00576	1.41e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CIPFEANN_00577	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CIPFEANN_00578	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
CIPFEANN_00579	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CIPFEANN_00580	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIPFEANN_00581	2.55e-169	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
CIPFEANN_00582	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CIPFEANN_00583	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CIPFEANN_00584	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
CIPFEANN_00585	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIPFEANN_00586	7.33e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
CIPFEANN_00587	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
CIPFEANN_00588	0.0	cadA	-	-	P	-	-	-	P-type ATPase
CIPFEANN_00589	5.23e-276	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
CIPFEANN_00590	4.44e-11	-	-	-	-	-	-	-	-
CIPFEANN_00591	1.83e-197	-	-	-	GM	-	-	-	NAD(P)H-binding
CIPFEANN_00592	3.87e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
CIPFEANN_00593	1.77e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
CIPFEANN_00594	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIPFEANN_00595	8.34e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_00596	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
CIPFEANN_00597	3.53e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
CIPFEANN_00598	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CIPFEANN_00599	4.82e-276	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CIPFEANN_00600	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIPFEANN_00601	4.92e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CIPFEANN_00602	8.4e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CIPFEANN_00603	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CIPFEANN_00604	4e-279	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
CIPFEANN_00605	1.41e-53	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
CIPFEANN_00606	5.71e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CIPFEANN_00607	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
CIPFEANN_00608	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CIPFEANN_00610	3.16e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CIPFEANN_00611	0.0	-	-	-	L	-	-	-	DNA helicase
CIPFEANN_00612	7.04e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
CIPFEANN_00613	5.96e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
CIPFEANN_00614	4.55e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CIPFEANN_00615	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
CIPFEANN_00616	1.09e-27	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
CIPFEANN_00621	1.13e-22	-	-	-	L	-	-	-	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CIPFEANN_00626	2.77e-134	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIPFEANN_00627	7.24e-27	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIPFEANN_00633	4.51e-29	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
CIPFEANN_00635	4.82e-11	-	-	-	-	-	-	-	-
CIPFEANN_00644	2.48e-15	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CIPFEANN_00645	5.46e-33	-	-	-	-	-	-	-	-
CIPFEANN_00651	1.95e-12	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
CIPFEANN_00657	1.17e-90	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
CIPFEANN_00658	1.05e-18	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
CIPFEANN_00659	2.34e-41	-	-	-	-	-	-	-	-
CIPFEANN_00660	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CIPFEANN_00661	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
CIPFEANN_00662	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CIPFEANN_00663	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
CIPFEANN_00664	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
CIPFEANN_00665	7.11e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
CIPFEANN_00666	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
CIPFEANN_00667	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
CIPFEANN_00668	5.16e-220	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
CIPFEANN_00669	1.71e-217	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
CIPFEANN_00670	4.79e-273	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
CIPFEANN_00671	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CIPFEANN_00672	5.52e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
CIPFEANN_00673	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
CIPFEANN_00674	2.43e-241	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
CIPFEANN_00675	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
CIPFEANN_00676	3.4e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CIPFEANN_00677	4.38e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
CIPFEANN_00678	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
CIPFEANN_00679	9.7e-168	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
CIPFEANN_00680	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
CIPFEANN_00681	1.8e-190	-	-	-	O	-	-	-	Band 7 protein
CIPFEANN_00682	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
CIPFEANN_00683	1.11e-201	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
CIPFEANN_00684	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
CIPFEANN_00685	3.92e-172	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
CIPFEANN_00686	5.02e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_00687	1.32e-131	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
CIPFEANN_00688	3.49e-124	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
CIPFEANN_00689	2.11e-219	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIPFEANN_00692	4.75e-79	-	-	-	-	-	-	-	-
CIPFEANN_00695	8.37e-14	-	-	-	T	-	-	-	SpoVT / AbrB like domain
CIPFEANN_00696	2.08e-30	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIPFEANN_00699	4.5e-63	-	-	-	L	-	-	-	four-way junction helicase activity
CIPFEANN_00707	0.000773	-	-	-	S	-	-	-	YopX protein
CIPFEANN_00718	1.59e-08	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
CIPFEANN_00723	2.28e-08	-	-	-	K	-	-	-	Peptidase S24-like
CIPFEANN_00725	1.45e-92	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIPFEANN_00727	1.39e-44	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CIPFEANN_00728	7.25e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
CIPFEANN_00729	4.38e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CIPFEANN_00730	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
CIPFEANN_00731	8.16e-212	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
CIPFEANN_00732	2.35e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
CIPFEANN_00733	0.0	-	-	-	L	-	-	-	Transposase
CIPFEANN_00734	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CIPFEANN_00735	6.8e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
CIPFEANN_00736	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
CIPFEANN_00737	3.98e-304	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
CIPFEANN_00738	3.39e-33	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
CIPFEANN_00739	3.18e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
CIPFEANN_00740	1.77e-56	-	-	-	-	-	-	-	-
CIPFEANN_00741	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CIPFEANN_00742	1.16e-263	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
CIPFEANN_00743	2.56e-188	-	-	-	S	-	-	-	Alpha beta hydrolase
CIPFEANN_00744	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CIPFEANN_00745	4.75e-132	-	-	-	-	-	-	-	-
CIPFEANN_00747	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CIPFEANN_00748	7.5e-85	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
CIPFEANN_00749	3.86e-205	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
CIPFEANN_00750	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
CIPFEANN_00751	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
CIPFEANN_00752	9.11e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
CIPFEANN_00753	1.76e-296	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CIPFEANN_00754	1.59e-303	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
CIPFEANN_00755	2.21e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
CIPFEANN_00756	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
CIPFEANN_00757	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
CIPFEANN_00758	5.19e-27	-	-	-	-	-	-	-	-
CIPFEANN_00759	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CIPFEANN_00760	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CIPFEANN_00761	9.54e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
CIPFEANN_00762	1.43e-141	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
CIPFEANN_00763	3.07e-265	-	-	-	G	-	-	-	Transporter, major facilitator family protein
CIPFEANN_00764	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
CIPFEANN_00765	7.07e-144	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
CIPFEANN_00766	1.3e-100	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CIPFEANN_00767	7.55e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CIPFEANN_00768	2.55e-119	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
CIPFEANN_00769	4.22e-244	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CIPFEANN_00770	4.47e-229	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
CIPFEANN_00772	6.02e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
CIPFEANN_00773	2.65e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CIPFEANN_00774	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CIPFEANN_00775	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CIPFEANN_00776	6.09e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
CIPFEANN_00777	3.7e-199	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CIPFEANN_00778	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
CIPFEANN_00779	2.23e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CIPFEANN_00780	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
CIPFEANN_00781	2.14e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CIPFEANN_00782	2.71e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
CIPFEANN_00783	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CIPFEANN_00784	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CIPFEANN_00785	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIPFEANN_00786	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CIPFEANN_00787	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
CIPFEANN_00788	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIPFEANN_00789	4.63e-255	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIPFEANN_00790	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
CIPFEANN_00791	3.1e-168	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
CIPFEANN_00792	8.01e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
CIPFEANN_00793	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
CIPFEANN_00794	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CIPFEANN_00796	2.91e-65	-	-	-	-	-	-	-	-
CIPFEANN_00801	1.47e-169	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIPFEANN_00803	5.7e-72	-	-	-	-	-	-	-	-
CIPFEANN_00804	1.95e-93	-	-	-	K	-	-	-	SIR2-like domain
CIPFEANN_00805	1.05e-90	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
CIPFEANN_00809	3.35e-89	-	-	-	K	-	-	-	Putative DNA-binding domain
CIPFEANN_00810	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
CIPFEANN_00811	5.22e-83	-	-	-	L	-	-	-	Type I restriction modification DNA specificity domain
CIPFEANN_00812	6.37e-256	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
CIPFEANN_00813	9.28e-13	-	-	-	-	-	-	-	-
CIPFEANN_00815	7.29e-84	-	-	-	-	-	-	-	-
CIPFEANN_00816	1.13e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CIPFEANN_00817	5.24e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CIPFEANN_00818	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
CIPFEANN_00819	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CIPFEANN_00820	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CIPFEANN_00821	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CIPFEANN_00822	1.01e-254	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
CIPFEANN_00824	4.78e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CIPFEANN_00826	7.92e-76	-	-	-	-	-	-	-	-
CIPFEANN_00828	5.65e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
CIPFEANN_00829	9.38e-197	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
CIPFEANN_00830	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
CIPFEANN_00831	1.88e-290	-	-	-	P	-	-	-	Chloride transporter, ClC family
CIPFEANN_00832	1.1e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CIPFEANN_00833	8.69e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CIPFEANN_00834	7.92e-180	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CIPFEANN_00835	4.3e-68	-	-	-	-	-	-	-	-
CIPFEANN_00836	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
CIPFEANN_00837	1.25e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
CIPFEANN_00838	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CIPFEANN_00839	4.29e-119	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
CIPFEANN_00840	2.71e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CIPFEANN_00841	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
CIPFEANN_00842	1.45e-55	-	-	-	-	-	-	-	-
CIPFEANN_00843	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CIPFEANN_00844	4.62e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CIPFEANN_00845	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
CIPFEANN_00846	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
CIPFEANN_00847	1.11e-224	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIPFEANN_00848	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
CIPFEANN_00849	3.08e-146	-	-	-	-	-	-	-	-
CIPFEANN_00850	8.42e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
CIPFEANN_00851	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIPFEANN_00852	1.52e-43	-	-	-	-	-	-	-	-
CIPFEANN_00853	1.05e-153	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CIPFEANN_00854	9.17e-59	-	-	-	-	-	-	-	-
CIPFEANN_00856	6.82e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CIPFEANN_00857	4.71e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
CIPFEANN_00858	3.36e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
CIPFEANN_00859	2.34e-284	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
CIPFEANN_00860	2.97e-136	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
CIPFEANN_00861	9.39e-277	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
CIPFEANN_00862	9.3e-61	-	-	-	-	-	-	-	-
CIPFEANN_00863	1.49e-54	-	-	-	-	-	-	-	-
CIPFEANN_00865	3.88e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CIPFEANN_00866	2.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CIPFEANN_00867	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
CIPFEANN_00868	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
CIPFEANN_00869	3.75e-77	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
CIPFEANN_00870	2.62e-282	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
CIPFEANN_00871	0.0	yhaN	-	-	L	-	-	-	AAA domain
CIPFEANN_00872	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CIPFEANN_00874	4.99e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
CIPFEANN_00875	2.7e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_00876	6.64e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CIPFEANN_00877	1.85e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CIPFEANN_00878	3.31e-37	-	-	-	S	-	-	-	YSIRK type signal peptide
CIPFEANN_00879	7.51e-77	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
CIPFEANN_00880	1.43e-311	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
CIPFEANN_00881	6.79e-183	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CIPFEANN_00882	1.92e-124	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CIPFEANN_00883	5.45e-232	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
CIPFEANN_00884	9.93e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
CIPFEANN_00885	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
CIPFEANN_00886	1.2e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
CIPFEANN_00887	1.63e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIPFEANN_00888	7.39e-64	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
CIPFEANN_00889	9.47e-48	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
CIPFEANN_00890	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
CIPFEANN_00891	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
CIPFEANN_00892	1.33e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
CIPFEANN_00893	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CIPFEANN_00894	2.74e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CIPFEANN_00895	1.02e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CIPFEANN_00896	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CIPFEANN_00897	3.31e-275	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
CIPFEANN_00898	9.62e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
CIPFEANN_00899	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CIPFEANN_00900	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
CIPFEANN_00901	2.23e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CIPFEANN_00902	3.17e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
CIPFEANN_00903	5.44e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
CIPFEANN_00904	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
CIPFEANN_00905	2.43e-158	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CIPFEANN_00906	3.6e-146	yqeK	-	-	H	-	-	-	Hydrolase, HD family
CIPFEANN_00907	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CIPFEANN_00908	1.1e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
CIPFEANN_00909	9.69e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
CIPFEANN_00910	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
CIPFEANN_00911	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
CIPFEANN_00912	1.38e-155	csrR	-	-	K	-	-	-	response regulator
CIPFEANN_00913	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIPFEANN_00914	0.0	potE	-	-	E	-	-	-	Amino Acid
CIPFEANN_00915	1.61e-292	-	-	-	V	-	-	-	MatE
CIPFEANN_00916	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
CIPFEANN_00917	3.89e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIPFEANN_00918	1.79e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
CIPFEANN_00919	2.22e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIPFEANN_00920	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CIPFEANN_00921	1.94e-76	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CIPFEANN_00922	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CIPFEANN_00923	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIPFEANN_00924	6.92e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
CIPFEANN_00925	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
CIPFEANN_00926	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIPFEANN_00927	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIPFEANN_00928	7.33e-253	-	-	-	EGP	-	-	-	Major Facilitator
CIPFEANN_00929	2.18e-115	ymdB	-	-	S	-	-	-	Macro domain protein
CIPFEANN_00930	2.13e-142	-	-	-	K	-	-	-	Helix-turn-helix domain
CIPFEANN_00931	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
CIPFEANN_00932	4.95e-63	-	-	-	-	-	-	-	-
CIPFEANN_00933	1.32e-307	-	-	-	S	-	-	-	Putative metallopeptidase domain
CIPFEANN_00934	1.46e-261	-	-	-	S	-	-	-	associated with various cellular activities
CIPFEANN_00935	1.92e-153	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
CIPFEANN_00936	3.47e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
CIPFEANN_00938	7.94e-150	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
CIPFEANN_00939	2.84e-73	-	-	-	-	-	-	-	-
CIPFEANN_00941	1.97e-131	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
CIPFEANN_00942	1.62e-34	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
CIPFEANN_00943	5.87e-65	-	-	-	-	-	-	-	-
CIPFEANN_00944	8.76e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
CIPFEANN_00945	6.07e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
CIPFEANN_00946	1.8e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CIPFEANN_00947	7.28e-138	-	-	-	NU	-	-	-	mannosyl-glycoprotein
CIPFEANN_00948	8.04e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
CIPFEANN_00949	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
CIPFEANN_00950	5.27e-64	-	-	-	-	-	-	-	-
CIPFEANN_00951	8.38e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
CIPFEANN_00952	1.99e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
CIPFEANN_00953	1.31e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CIPFEANN_00954	4.27e-194	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
CIPFEANN_00955	1.82e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIPFEANN_00956	3.52e-161	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
CIPFEANN_00957	9.4e-197	-	-	-	-	-	-	-	-
CIPFEANN_00958	6.13e-149	-	-	-	M	-	-	-	Glycosyl transferase
CIPFEANN_00959	8.91e-293	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
CIPFEANN_00960	2.23e-47	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
CIPFEANN_00961	6.49e-49	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
CIPFEANN_00963	0.0	snf	-	-	KL	-	-	-	domain protein
CIPFEANN_00964	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
CIPFEANN_00965	8e-225	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CIPFEANN_00966	5.31e-264	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CIPFEANN_00967	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
CIPFEANN_00968	7.36e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
CIPFEANN_00969	5.18e-222	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
CIPFEANN_00970	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
CIPFEANN_00971	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CIPFEANN_00972	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIPFEANN_00973	3.22e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
CIPFEANN_00975	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
CIPFEANN_00976	2.49e-43	-	-	-	-	-	-	-	-
CIPFEANN_00977	6.83e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CIPFEANN_00978	1.32e-225	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIPFEANN_00979	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
CIPFEANN_00980	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIPFEANN_00981	1.4e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
CIPFEANN_00982	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
CIPFEANN_00984	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CIPFEANN_00985	1.22e-289	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
CIPFEANN_00986	2.04e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
CIPFEANN_00987	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
CIPFEANN_00988	6.28e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIPFEANN_00989	1.3e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIPFEANN_00990	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIPFEANN_00991	1.43e-185	-	-	-	S	-	-	-	DUF218 domain
CIPFEANN_00992	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
CIPFEANN_00993	5.51e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
CIPFEANN_00994	2.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
CIPFEANN_00995	2.9e-309	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
CIPFEANN_00996	9.49e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
CIPFEANN_00997	6.14e-104	-	-	-	S	-	-	-	Cupin domain
CIPFEANN_00998	2.91e-109	-	-	-	C	-	-	-	Flavodoxin
CIPFEANN_00999	1.49e-176	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
CIPFEANN_01000	0.0	-	-	-	M	-	-	-	domain protein
CIPFEANN_01001	2.01e-76	-	-	-	-	-	-	-	-
CIPFEANN_01002	9.5e-239	ampC	-	-	V	-	-	-	Beta-lactamase
CIPFEANN_01003	1.25e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
CIPFEANN_01004	1.77e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CIPFEANN_01005	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
CIPFEANN_01006	1.97e-297	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
CIPFEANN_01007	4.87e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
CIPFEANN_01008	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
CIPFEANN_01009	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
CIPFEANN_01010	4.07e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CIPFEANN_01011	1.86e-208	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CIPFEANN_01012	6.29e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CIPFEANN_01013	2.47e-66	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CIPFEANN_01014	1.22e-208	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CIPFEANN_01015	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CIPFEANN_01016	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIPFEANN_01017	6.71e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
CIPFEANN_01018	4.71e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
CIPFEANN_01020	6.34e-95	-	-	-	-	-	-	-	-
CIPFEANN_01021	7.92e-221	-	-	-	-	-	-	-	-
CIPFEANN_01022	7.67e-229	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
CIPFEANN_01023	4.82e-180	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CIPFEANN_01024	4.18e-165	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIPFEANN_01025	1.79e-101	-	-	-	S	-	-	-	Flavodoxin
CIPFEANN_01026	3.25e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
CIPFEANN_01027	4.04e-48	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
CIPFEANN_01028	5.25e-279	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
CIPFEANN_01029	4.74e-213	-	-	-	H	-	-	-	geranyltranstransferase activity
CIPFEANN_01030	9.46e-235	-	-	-	-	-	-	-	-
CIPFEANN_01031	3.11e-26	-	-	-	-	-	-	-	-
CIPFEANN_01032	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
CIPFEANN_01033	9.18e-243	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
CIPFEANN_01034	1.56e-60	-	-	-	-	-	-	-	-
CIPFEANN_01035	2.37e-135	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CIPFEANN_01036	9.66e-110	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
CIPFEANN_01037	2.19e-291	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
CIPFEANN_01038	1.65e-107	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
CIPFEANN_01039	2.33e-239	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
CIPFEANN_01040	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CIPFEANN_01041	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
CIPFEANN_01042	4.54e-125	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
CIPFEANN_01043	7.16e-163	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
CIPFEANN_01044	1.33e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
CIPFEANN_01045	0.0	-	-	-	S	-	-	-	membrane
CIPFEANN_01046	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CIPFEANN_01047	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CIPFEANN_01048	9.34e-130	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CIPFEANN_01049	1.43e-16	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
CIPFEANN_01050	7.32e-35	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
CIPFEANN_01051	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
CIPFEANN_01052	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
CIPFEANN_01053	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
CIPFEANN_01054	2.39e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
CIPFEANN_01055	1.01e-226	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CIPFEANN_01056	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CIPFEANN_01057	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIPFEANN_01058	3.3e-280	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CIPFEANN_01059	1.28e-18	-	-	-	-	-	-	-	-
CIPFEANN_01060	1.9e-194	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CIPFEANN_01061	7.55e-107	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
CIPFEANN_01062	1.49e-309	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
CIPFEANN_01063	4.78e-179	-	-	-	V	-	-	-	Beta-lactamase enzyme family
CIPFEANN_01064	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
CIPFEANN_01065	6.33e-275	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
CIPFEANN_01066	0.0	arcT	-	-	E	-	-	-	Dipeptidase
CIPFEANN_01067	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
CIPFEANN_01068	2.13e-227	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
CIPFEANN_01069	1.19e-215	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
CIPFEANN_01070	6.14e-173	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CIPFEANN_01071	1.67e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
CIPFEANN_01072	6.72e-87	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CIPFEANN_01073	9.19e-13	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CIPFEANN_01074	3.23e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
CIPFEANN_01075	7.72e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
CIPFEANN_01076	5.66e-295	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CIPFEANN_01077	6.26e-113	-	-	-	Q	-	-	-	Methyltransferase
CIPFEANN_01078	3.26e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
CIPFEANN_01079	2.26e-303	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
CIPFEANN_01080	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
CIPFEANN_01081	6.53e-133	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
CIPFEANN_01082	7.23e-239	-	-	-	I	-	-	-	Alpha beta
CIPFEANN_01083	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
CIPFEANN_01084	2.22e-151	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
CIPFEANN_01085	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
CIPFEANN_01086	7.21e-205	-	-	-	K	-	-	-	LysR family
CIPFEANN_01087	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
CIPFEANN_01088	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
CIPFEANN_01089	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CIPFEANN_01090	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
CIPFEANN_01091	5.46e-207	mleR	-	-	K	-	-	-	LysR family
CIPFEANN_01092	2.87e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CIPFEANN_01093	1.35e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
CIPFEANN_01094	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
CIPFEANN_01095	2.47e-212	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
CIPFEANN_01096	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
CIPFEANN_01097	1.36e-35	-	-	-	-	-	-	-	-
CIPFEANN_01100	3.3e-203	-	-	-	J	-	-	-	Methyltransferase
CIPFEANN_01101	2.1e-288	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
CIPFEANN_01102	4.94e-285	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIPFEANN_01103	1.03e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
CIPFEANN_01105	0.0	-	-	-	-	-	-	-	-
CIPFEANN_01106	1.87e-178	-	-	-	-	-	-	-	-
CIPFEANN_01107	2.21e-101	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
CIPFEANN_01109	4.35e-14	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
CIPFEANN_01112	2.45e-51	-	-	-	D	-	-	-	nuclear chromosome segregation
CIPFEANN_01113	7.62e-10	-	-	-	K	-	-	-	sequence-specific DNA binding
CIPFEANN_01114	0.0	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
CIPFEANN_01115	9.83e-106	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIPFEANN_01116	2.26e-65	-	-	-	-	-	-	-	-
CIPFEANN_01118	8.11e-76	-	-	-	K	-	-	-	Peptidase S24-like
CIPFEANN_01119	1.46e-31	-	-	-	K	-	-	-	Protein of unknown function (DUF739)
CIPFEANN_01128	0.000499	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
CIPFEANN_01129	6.97e-81	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
CIPFEANN_01130	1.88e-83	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
CIPFEANN_01131	3.91e-59	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
CIPFEANN_01132	6.35e-76	-	-	-	-	-	-	-	-
CIPFEANN_01137	8.47e-07	-	-	-	-	-	-	-	-
CIPFEANN_01138	9.52e-14	-	-	-	-	-	-	-	-
CIPFEANN_01139	6.8e-37	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
CIPFEANN_01140	7.8e-24	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
CIPFEANN_01141	3.28e-96	-	-	-	-	-	-	-	-
CIPFEANN_01143	6.91e-58	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
CIPFEANN_01144	5.81e-171	-	-	-	S	-	-	-	Pfam:Terminase_3C
CIPFEANN_01145	5.42e-163	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
CIPFEANN_01146	4.73e-93	-	-	-	S	-	-	-	Phage minor capsid protein 2
CIPFEANN_01148	2.04e-14	-	-	-	S	-	-	-	Phage minor capsid protein 2
CIPFEANN_01150	1.5e-28	-	-	-	S	-	-	-	Phage minor structural protein GP20
CIPFEANN_01151	1.33e-122	-	-	-	-	-	-	-	-
CIPFEANN_01153	4.06e-39	-	-	-	S	-	-	-	Minor capsid protein
CIPFEANN_01155	5.78e-13	-	-	-	S	-	-	-	Minor capsid protein from bacteriophage
CIPFEANN_01156	4.03e-52	-	-	-	N	-	-	-	domain, Protein
CIPFEANN_01158	1.07e-44	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
CIPFEANN_01159	8.24e-125	-	-	-	S	-	-	-	peptidoglycan catabolic process
CIPFEANN_01161	1.04e-67	-	-	-	M	-	-	-	Prophage endopeptidase tail
CIPFEANN_01164	1.05e-101	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
CIPFEANN_01168	2.02e-41	-	-	-	-	-	-	-	-
CIPFEANN_01169	9.1e-70	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
CIPFEANN_01170	6.56e-236	-	-	-	M	-	-	-	hydrolase, family 25
CIPFEANN_01171	3.84e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CIPFEANN_01172	1.29e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CIPFEANN_01173	1e-146	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
CIPFEANN_01174	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
CIPFEANN_01175	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CIPFEANN_01176	1.61e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CIPFEANN_01177	1.09e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIPFEANN_01178	4.02e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIPFEANN_01179	2.83e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CIPFEANN_01180	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
CIPFEANN_01181	3.2e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CIPFEANN_01182	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
CIPFEANN_01183	9e-72	-	-	-	-	-	-	-	-
CIPFEANN_01184	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CIPFEANN_01185	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CIPFEANN_01186	4.44e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CIPFEANN_01187	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CIPFEANN_01188	8.26e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CIPFEANN_01189	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CIPFEANN_01190	4.26e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
CIPFEANN_01191	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
CIPFEANN_01192	3.75e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CIPFEANN_01193	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
CIPFEANN_01194	6.95e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
CIPFEANN_01195	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
CIPFEANN_01196	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CIPFEANN_01197	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
CIPFEANN_01198	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CIPFEANN_01199	4.72e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CIPFEANN_01200	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIPFEANN_01201	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CIPFEANN_01202	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
CIPFEANN_01203	4.94e-285	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CIPFEANN_01204	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CIPFEANN_01205	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CIPFEANN_01206	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
CIPFEANN_01207	2.17e-52	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
CIPFEANN_01208	1.53e-118	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CIPFEANN_01209	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
CIPFEANN_01210	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
CIPFEANN_01211	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CIPFEANN_01212	3.67e-46	-	-	-	-	-	-	-	-
CIPFEANN_01213	9e-72	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
CIPFEANN_01214	8.83e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
CIPFEANN_01215	1.55e-109	-	-	-	-	-	-	-	-
CIPFEANN_01216	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CIPFEANN_01217	4.29e-175	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_01218	5.89e-231	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
CIPFEANN_01219	8.74e-161	XK27_10500	-	-	K	-	-	-	response regulator
CIPFEANN_01220	7.23e-202	yvgN	-	-	S	-	-	-	Aldo keto reductase
CIPFEANN_01221	9.74e-176	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
CIPFEANN_01222	4.74e-107	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIPFEANN_01223	2.24e-261	-	-	-	-	-	-	-	-
CIPFEANN_01224	5.06e-68	-	-	-	-	-	-	-	-
CIPFEANN_01225	1.21e-48	-	-	-	-	-	-	-	-
CIPFEANN_01226	5.55e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
CIPFEANN_01227	4.68e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CIPFEANN_01228	1.34e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
CIPFEANN_01229	8.5e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CIPFEANN_01230	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
CIPFEANN_01231	1.97e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CIPFEANN_01232	2.56e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
CIPFEANN_01233	3.7e-297	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CIPFEANN_01234	1.39e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
CIPFEANN_01235	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
CIPFEANN_01236	9.42e-57	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
CIPFEANN_01237	5.14e-70	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
CIPFEANN_01238	9.08e-317	-	-	-	E	ko:K03294	-	ko00000	amino acid
CIPFEANN_01239	1.63e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIPFEANN_01241	1.94e-269	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
CIPFEANN_01242	4.51e-54	-	-	-	S	-	-	-	Cytochrome B5
CIPFEANN_01243	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
CIPFEANN_01244	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
CIPFEANN_01245	5.36e-92	-	-	-	S	ko:K02348	-	ko00000	Gnat family
CIPFEANN_01246	7.48e-155	-	-	-	GM	-	-	-	NmrA-like family
CIPFEANN_01247	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CIPFEANN_01248	3.2e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
CIPFEANN_01249	9.01e-57	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CIPFEANN_01250	2.59e-34	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CIPFEANN_01251	7.97e-292	-	-	-	-	-	-	-	-
CIPFEANN_01252	7.6e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIPFEANN_01253	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
CIPFEANN_01254	7.17e-146	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
CIPFEANN_01255	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
CIPFEANN_01256	5.35e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
CIPFEANN_01257	1.43e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
CIPFEANN_01258	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
CIPFEANN_01259	2.63e-53	-	-	-	-	-	-	-	-
CIPFEANN_01260	0.0	ydaO	-	-	E	-	-	-	amino acid
CIPFEANN_01261	0.0	-	-	-	E	-	-	-	amino acid
CIPFEANN_01262	3.11e-106	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
CIPFEANN_01263	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CIPFEANN_01264	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CIPFEANN_01266	1.34e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CIPFEANN_01267	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
CIPFEANN_01268	1.39e-231	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIPFEANN_01269	1.41e-285	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CIPFEANN_01270	1.82e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
CIPFEANN_01271	4.25e-176	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CIPFEANN_01272	6.3e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CIPFEANN_01273	2.55e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIPFEANN_01274	2.12e-253	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CIPFEANN_01275	5.02e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
CIPFEANN_01276	7.34e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
CIPFEANN_01277	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CIPFEANN_01278	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
CIPFEANN_01279	1.91e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
CIPFEANN_01280	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
CIPFEANN_01281	3.47e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
CIPFEANN_01282	2.95e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
CIPFEANN_01283	8.8e-264	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
CIPFEANN_01284	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
CIPFEANN_01285	3.61e-61	-	-	-	-	-	-	-	-
CIPFEANN_01286	1.88e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
CIPFEANN_01287	2.03e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CIPFEANN_01288	9.79e-29	-	-	-	-	-	-	-	-
CIPFEANN_01289	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
CIPFEANN_01290	4.16e-180	-	-	-	S	-	-	-	Membrane
CIPFEANN_01291	8.18e-174	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
CIPFEANN_01292	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
CIPFEANN_01293	1.35e-170	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CIPFEANN_01294	5.36e-133	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CIPFEANN_01295	5.53e-301	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
CIPFEANN_01296	5.52e-292	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CIPFEANN_01297	8.28e-135	-	-	-	V	-	-	-	VanZ like family
CIPFEANN_01298	7.03e-33	-	-	-	-	-	-	-	-
CIPFEANN_01299	5.03e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
CIPFEANN_01300	3.77e-102	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CIPFEANN_01301	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
CIPFEANN_01302	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CIPFEANN_01303	7.77e-198	yeaE	-	-	S	-	-	-	Aldo keto
CIPFEANN_01304	4.57e-137	-	-	-	M	-	-	-	LysM domain protein
CIPFEANN_01305	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
CIPFEANN_01306	2.73e-148	-	-	-	M	-	-	-	LysM domain protein
CIPFEANN_01307	3.48e-192	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
CIPFEANN_01308	3.94e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CIPFEANN_01309	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
CIPFEANN_01310	1.63e-312	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
CIPFEANN_01311	1.74e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CIPFEANN_01321	3.1e-67	-	-	-	L	-	-	-	Transposase
CIPFEANN_01322	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CIPFEANN_01323	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CIPFEANN_01324	2.48e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CIPFEANN_01325	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CIPFEANN_01326	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CIPFEANN_01327	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
CIPFEANN_01328	6.92e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
CIPFEANN_01329	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CIPFEANN_01330	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CIPFEANN_01331	1.22e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CIPFEANN_01332	5.23e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
CIPFEANN_01333	2.99e-218	yvgN	-	-	C	-	-	-	Aldo keto reductase
CIPFEANN_01334	7.35e-12	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
CIPFEANN_01335	7.87e-24	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
CIPFEANN_01336	3.36e-305	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
CIPFEANN_01337	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CIPFEANN_01338	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
CIPFEANN_01339	2.07e-202	gspA	-	-	M	-	-	-	family 8
CIPFEANN_01340	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CIPFEANN_01341	7.49e-124	-	-	-	-	-	-	-	-
CIPFEANN_01342	1.2e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
CIPFEANN_01343	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
CIPFEANN_01344	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CIPFEANN_01345	9.15e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
CIPFEANN_01346	5.61e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CIPFEANN_01347	6.71e-92	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CIPFEANN_01348	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
CIPFEANN_01349	2.57e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
CIPFEANN_01350	9.83e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
CIPFEANN_01351	4.13e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
CIPFEANN_01353	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
CIPFEANN_01354	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
CIPFEANN_01356	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
CIPFEANN_01357	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIPFEANN_01358	6.85e-315	yycH	-	-	S	-	-	-	YycH protein
CIPFEANN_01359	1.18e-191	yycI	-	-	S	-	-	-	YycH protein
CIPFEANN_01360	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
CIPFEANN_01361	1.3e-282	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
CIPFEANN_01362	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
CIPFEANN_01363	5.51e-220	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CIPFEANN_01364	3.07e-114	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CIPFEANN_01366	2.47e-230	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
CIPFEANN_01367	1.1e-125	-	-	-	S	-	-	-	reductase
CIPFEANN_01368	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
CIPFEANN_01369	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
CIPFEANN_01371	3.77e-245	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
CIPFEANN_01372	3.34e-189	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
CIPFEANN_01373	3.45e-246	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
CIPFEANN_01374	4.53e-272	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
CIPFEANN_01375	1.05e-197	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
CIPFEANN_01376	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CIPFEANN_01377	1.92e-284	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CIPFEANN_01378	1.21e-247	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CIPFEANN_01381	2.92e-33	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
CIPFEANN_01382	3.96e-154	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
CIPFEANN_01383	1.66e-303	-	-	-	T	-	-	-	GHKL domain
CIPFEANN_01384	2.28e-139	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
CIPFEANN_01385	1.01e-52	-	-	-	P	-	-	-	FAD-binding domain
CIPFEANN_01386	4.47e-12	-	-	-	P	-	-	-	FAD-binding domain
CIPFEANN_01387	1.16e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
CIPFEANN_01388	1.2e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIPFEANN_01389	4.09e-99	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CIPFEANN_01390	2.32e-210	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
CIPFEANN_01391	1.94e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
CIPFEANN_01392	2.67e-111	-	-	-	C	-	-	-	Flavodoxin
CIPFEANN_01393	2.15e-203	lysR	-	-	K	-	-	-	Transcriptional regulator
CIPFEANN_01394	7.41e-114	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
CIPFEANN_01395	8.09e-44	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
CIPFEANN_01396	2.05e-195	-	-	-	S	-	-	-	Alpha beta hydrolase
CIPFEANN_01397	2.49e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
CIPFEANN_01398	5.05e-121	-	-	-	K	-	-	-	Virulence activator alpha C-term
CIPFEANN_01399	9.8e-84	-	-	-	GM	-	-	-	NAD(P)H-binding
CIPFEANN_01400	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
CIPFEANN_01401	1.81e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
CIPFEANN_01402	1.21e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CIPFEANN_01403	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CIPFEANN_01404	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CIPFEANN_01405	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
CIPFEANN_01406	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
CIPFEANN_01407	1.68e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
CIPFEANN_01408	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
CIPFEANN_01409	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIPFEANN_01410	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CIPFEANN_01411	5.46e-297	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
CIPFEANN_01412	1.18e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
CIPFEANN_01413	1.83e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CIPFEANN_01414	4.23e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CIPFEANN_01415	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
CIPFEANN_01416	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CIPFEANN_01417	5.87e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
CIPFEANN_01418	1.02e-233	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIPFEANN_01419	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
CIPFEANN_01420	5.9e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
CIPFEANN_01421	7.51e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
CIPFEANN_01422	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
CIPFEANN_01423	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
CIPFEANN_01424	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CIPFEANN_01425	2.88e-270	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
CIPFEANN_01426	7.77e-159	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIPFEANN_01428	1.26e-121	-	-	-	-	-	-	-	-
CIPFEANN_01429	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CIPFEANN_01430	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
CIPFEANN_01431	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIPFEANN_01432	3.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CIPFEANN_01433	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CIPFEANN_01434	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CIPFEANN_01435	2.44e-20	-	-	-	-	-	-	-	-
CIPFEANN_01436	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
CIPFEANN_01437	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
CIPFEANN_01438	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CIPFEANN_01439	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CIPFEANN_01440	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CIPFEANN_01441	3.58e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
CIPFEANN_01442	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIPFEANN_01443	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CIPFEANN_01444	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
CIPFEANN_01445	9.21e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
CIPFEANN_01446	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
CIPFEANN_01447	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
CIPFEANN_01448	4.14e-139	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
CIPFEANN_01449	1.23e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
CIPFEANN_01450	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CIPFEANN_01451	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
CIPFEANN_01452	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
CIPFEANN_01453	7.54e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
CIPFEANN_01454	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
CIPFEANN_01455	3.52e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
CIPFEANN_01456	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
CIPFEANN_01457	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
CIPFEANN_01458	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CIPFEANN_01459	9.42e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
CIPFEANN_01460	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
CIPFEANN_01461	1.38e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CIPFEANN_01462	6.08e-102	-	-	-	-	-	-	-	-
CIPFEANN_01463	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
CIPFEANN_01464	1.69e-229	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
CIPFEANN_01465	4.37e-39	-	-	-	-	-	-	-	-
CIPFEANN_01466	8.15e-259	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CIPFEANN_01468	5.28e-76	-	-	-	-	-	-	-	-
CIPFEANN_01469	7.55e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
CIPFEANN_01470	6.63e-281	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
CIPFEANN_01471	5.77e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
CIPFEANN_01472	2.58e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CIPFEANN_01473	1.62e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CIPFEANN_01474	1.43e-177	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CIPFEANN_01475	9.32e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIPFEANN_01476	1.64e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CIPFEANN_01477	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CIPFEANN_01478	5.89e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CIPFEANN_01479	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
CIPFEANN_01480	3.17e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CIPFEANN_01481	3.66e-38	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CIPFEANN_01482	8.85e-147	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIPFEANN_01488	1.31e-130	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CIPFEANN_01490	6e-84	-	-	-	S	-	-	-	dextransucrase activity
CIPFEANN_01491	6.55e-216	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
CIPFEANN_01492	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
CIPFEANN_01493	4.51e-101	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
CIPFEANN_01494	7.38e-225	ydhF	-	-	S	-	-	-	Aldo keto reductase
CIPFEANN_01496	8.69e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIPFEANN_01497	4.16e-56	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
CIPFEANN_01498	2.14e-133	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
CIPFEANN_01500	5.18e-78	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CIPFEANN_01501	4.57e-137	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CIPFEANN_01502	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
CIPFEANN_01503	2.69e-51	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
CIPFEANN_01504	1.63e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
CIPFEANN_01505	3.88e-50	-	-	-	-	-	-	-	-
CIPFEANN_01506	8.61e-168	-	-	-	IQ	-	-	-	dehydrogenase reductase
CIPFEANN_01507	1.17e-304	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
CIPFEANN_01508	3.43e-85	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIPFEANN_01509	2.3e-94	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
CIPFEANN_01510	1.36e-222	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
CIPFEANN_01511	3.82e-255	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIPFEANN_01513	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CIPFEANN_01514	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
CIPFEANN_01515	1.33e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CIPFEANN_01516	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIPFEANN_01517	3.95e-203	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
CIPFEANN_01518	1.05e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
CIPFEANN_01519	1.21e-286	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CIPFEANN_01520	6.2e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CIPFEANN_01521	4.61e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CIPFEANN_01522	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
CIPFEANN_01523	6.9e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CIPFEANN_01524	1.55e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
CIPFEANN_01525	7.89e-168	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
CIPFEANN_01532	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CIPFEANN_01533	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CIPFEANN_01534	1.79e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CIPFEANN_01535	1.33e-313	-	-	-	M	-	-	-	Glycosyl transferase family group 2
CIPFEANN_01537	1.86e-288	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
CIPFEANN_01538	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CIPFEANN_01539	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CIPFEANN_01540	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
CIPFEANN_01541	2.9e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CIPFEANN_01542	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CIPFEANN_01543	1.05e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIPFEANN_01544	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CIPFEANN_01545	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CIPFEANN_01546	3.06e-222	-	-	-	L	-	-	-	PFAM Integrase catalytic region
CIPFEANN_01547	3.59e-69	-	-	-	L	-	-	-	Helicase C-terminal domain protein
CIPFEANN_01548	3.96e-61	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
CIPFEANN_01550	5.04e-210	-	-	-	S	-	-	-	Protein of unknown function DUF262
CIPFEANN_01551	1.33e-47	-	-	-	-	-	-	-	-
CIPFEANN_01552	9.3e-13	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CIPFEANN_01553	4.72e-220	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CIPFEANN_01554	2.27e-190	epsB	-	-	M	-	-	-	biosynthesis protein
CIPFEANN_01555	2.21e-154	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
CIPFEANN_01556	2.07e-131	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
CIPFEANN_01557	3.2e-95	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
CIPFEANN_01558	3.58e-72	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
CIPFEANN_01559	1.08e-170	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
CIPFEANN_01560	2.75e-63	-	-	-	M	-	-	-	Glycosyl transferases group 1
CIPFEANN_01561	6.92e-105	-	2.7.8.12	GT2	S	ko:K09809,ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
CIPFEANN_01562	3.89e-46	-	-	-	-	-	-	-	-
CIPFEANN_01563	1.81e-46	cysE_1	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
CIPFEANN_01564	3.61e-86	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
CIPFEANN_01565	1.44e-131	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
CIPFEANN_01566	1.75e-63	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
CIPFEANN_01567	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CIPFEANN_01568	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
CIPFEANN_01569	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CIPFEANN_01570	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CIPFEANN_01571	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CIPFEANN_01572	8.8e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CIPFEANN_01573	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CIPFEANN_01574	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CIPFEANN_01575	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
CIPFEANN_01576	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CIPFEANN_01577	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CIPFEANN_01578	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CIPFEANN_01579	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CIPFEANN_01580	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CIPFEANN_01581	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CIPFEANN_01582	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CIPFEANN_01583	1.2e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CIPFEANN_01584	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
CIPFEANN_01585	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CIPFEANN_01586	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CIPFEANN_01587	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CIPFEANN_01588	9.82e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CIPFEANN_01589	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
CIPFEANN_01590	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CIPFEANN_01591	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CIPFEANN_01592	8.91e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIPFEANN_01593	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
CIPFEANN_01594	2.88e-251	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
CIPFEANN_01595	1.37e-72	-	-	-	-	-	-	-	-
CIPFEANN_01597	6.01e-35	-	-	-	-	-	-	-	-
CIPFEANN_01598	1.48e-238	-	-	-	U	-	-	-	type IV secretory pathway VirB4
CIPFEANN_01600	1.79e-64	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CIPFEANN_01603	0.000969	ydiL	-	-	S	ko:K07052	-	ko00000	protease
CIPFEANN_01606	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
CIPFEANN_01607	1.17e-61	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
CIPFEANN_01608	3.86e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
CIPFEANN_01609	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
CIPFEANN_01610	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
CIPFEANN_01611	1.05e-308	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIPFEANN_01612	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
CIPFEANN_01613	1.05e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
CIPFEANN_01614	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CIPFEANN_01615	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CIPFEANN_01616	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CIPFEANN_01617	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIPFEANN_01618	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CIPFEANN_01619	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIPFEANN_01620	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
CIPFEANN_01621	2.6e-154	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
CIPFEANN_01622	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CIPFEANN_01623	1.13e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
CIPFEANN_01624	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIPFEANN_01625	2.06e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
CIPFEANN_01626	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
CIPFEANN_01627	2.13e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
CIPFEANN_01628	4.04e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
CIPFEANN_01629	2.06e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_01630	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CIPFEANN_01631	1.62e-118	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
CIPFEANN_01632	4.46e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
CIPFEANN_01633	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
CIPFEANN_01634	1.66e-155	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
CIPFEANN_01635	3e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CIPFEANN_01636	9.02e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
CIPFEANN_01637	2.6e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CIPFEANN_01638	2.57e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
CIPFEANN_01639	2.26e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
CIPFEANN_01640	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIPFEANN_01641	9.99e-68	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
CIPFEANN_01642	4.84e-233	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
CIPFEANN_01645	1.45e-153	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
CIPFEANN_01646	1.95e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CIPFEANN_01647	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
CIPFEANN_01648	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
CIPFEANN_01649	3.2e-185	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
CIPFEANN_01650	4.44e-91	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
CIPFEANN_01651	4.47e-95	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
CIPFEANN_01652	2.56e-152	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CIPFEANN_01653	1.41e-98	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
CIPFEANN_01654	4.6e-305	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
CIPFEANN_01655	2.77e-223	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
CIPFEANN_01656	6.56e-174	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CIPFEANN_01657	6.66e-246	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CIPFEANN_01658	3.85e-75	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
CIPFEANN_01659	2.78e-302	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
CIPFEANN_01660	7.19e-155	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
CIPFEANN_01661	4.42e-130	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CIPFEANN_01662	8.36e-59	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CIPFEANN_01663	2.23e-157	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CIPFEANN_01664	5.52e-117	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
CIPFEANN_01665	1.39e-138	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
CIPFEANN_01666	7.61e-220	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
CIPFEANN_01667	1.43e-123	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
CIPFEANN_01668	7.98e-166	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
CIPFEANN_01669	1.34e-182	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
CIPFEANN_01670	8.16e-165	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
CIPFEANN_01671	2.02e-99	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
CIPFEANN_01672	9.45e-101	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
CIPFEANN_01673	1.2e-245	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CIPFEANN_01674	3.17e-138	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
CIPFEANN_01675	8.37e-184	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CIPFEANN_01676	1.64e-258	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
CIPFEANN_01677	4.01e-215	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
CIPFEANN_01678	1.72e-102	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
CIPFEANN_01679	1.91e-144	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
CIPFEANN_01680	4.54e-95	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
CIPFEANN_01681	1.44e-90	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
CIPFEANN_01682	3.45e-87	-	-	-	P	-	-	-	Cadmium resistance transporter
CIPFEANN_01683	1.06e-96	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
CIPFEANN_01684	1.08e-147	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
CIPFEANN_01685	9.15e-72	-	-	-	E	ko:K04031	-	ko00000	BMC
CIPFEANN_01686	2.5e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIPFEANN_01687	4.33e-259	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
CIPFEANN_01688	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
CIPFEANN_01689	1.68e-103	pduO	-	-	S	-	-	-	Haem-degrading
CIPFEANN_01690	6e-136	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
CIPFEANN_01691	5.63e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
CIPFEANN_01692	1.25e-103	-	-	-	S	-	-	-	Putative propanediol utilisation
CIPFEANN_01693	1.98e-148	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
CIPFEANN_01694	3.65e-53	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
CIPFEANN_01695	4.63e-75	-	-	-	CQ	-	-	-	BMC
CIPFEANN_01696	5.18e-59	pduH	-	-	S	-	-	-	Dehydratase medium subunit
CIPFEANN_01697	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
CIPFEANN_01698	3.09e-97	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
CIPFEANN_01699	5e-162	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
CIPFEANN_01700	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
CIPFEANN_01701	3.41e-170	pduB	-	-	E	-	-	-	BMC
CIPFEANN_01702	2.33e-50	-	-	-	CQ	-	-	-	BMC
CIPFEANN_01703	1.69e-202	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CIPFEANN_01704	4.02e-177	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
CIPFEANN_01705	2.7e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CIPFEANN_01706	4.54e-119	-	-	-	-	-	-	-	-
CIPFEANN_01707	8.33e-161	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
CIPFEANN_01708	8.61e-214	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
CIPFEANN_01709	1.5e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
CIPFEANN_01710	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
CIPFEANN_01711	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
CIPFEANN_01712	1.83e-113	-	-	-	GM	-	-	-	epimerase
CIPFEANN_01713	1.39e-198	-	-	-	V	-	-	-	(ABC) transporter
CIPFEANN_01714	1.67e-307	yhdP	-	-	S	-	-	-	Transporter associated domain
CIPFEANN_01715	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
CIPFEANN_01716	1.5e-96	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
CIPFEANN_01717	2.64e-246	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
CIPFEANN_01718	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CIPFEANN_01719	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CIPFEANN_01720	6e-39	-	-	-	-	-	-	-	-
CIPFEANN_01721	9.45e-06	-	-	-	-	-	-	-	-
CIPFEANN_01730	4.41e-52	-	-	-	K	-	-	-	Helix-turn-helix domain
CIPFEANN_01731	1.5e-80	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
CIPFEANN_01732	9.73e-132	-	-	-	L	-	-	-	Integrase
CIPFEANN_01733	1.38e-59	-	-	-	-	-	-	-	-
CIPFEANN_01734	3.34e-215	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CIPFEANN_01735	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
CIPFEANN_01736	3.43e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
CIPFEANN_01737	1.85e-127	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
CIPFEANN_01738	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
CIPFEANN_01739	8.25e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
CIPFEANN_01740	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CIPFEANN_01741	6.06e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_01742	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CIPFEANN_01743	1.26e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
CIPFEANN_01744	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CIPFEANN_01745	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CIPFEANN_01746	4.8e-72	-	-	-	-	-	-	-	-
CIPFEANN_01747	1.66e-165	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CIPFEANN_01748	4.65e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
CIPFEANN_01750	0.0	-	-	-	L	-	-	-	Transposase
CIPFEANN_01752	5.52e-227	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
CIPFEANN_01754	2.5e-145	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIPFEANN_01755	9.7e-162	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
CIPFEANN_01757	7.06e-98	bamA	-	-	GM	ko:K07277,ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029	domain, Protein
CIPFEANN_01758	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CIPFEANN_01759	1.21e-24	-	-	-	-	-	-	-	-
CIPFEANN_01760	4.55e-118	-	-	-	M	-	-	-	Glycosyl transferase family 2
CIPFEANN_01761	1.32e-298	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CIPFEANN_01762	9.19e-233	yueF	-	-	S	-	-	-	AI-2E family transporter
CIPFEANN_01763	3.32e-76	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	dextransucrase activity
CIPFEANN_01766	1.62e-69	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIPFEANN_01767	1.29e-228	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIPFEANN_01768	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
CIPFEANN_01769	2.14e-32	-	-	-	-	-	-	-	-
CIPFEANN_01770	1.03e-146	-	-	-	-	-	-	-	-
CIPFEANN_01771	4.99e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
CIPFEANN_01772	6.55e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
CIPFEANN_01773	2.46e-113	-	-	-	-	-	-	-	-
CIPFEANN_01774	4.3e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
CIPFEANN_01775	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
CIPFEANN_01776	1.07e-119	-	-	-	L	-	-	-	Integrase
CIPFEANN_01778	3.09e-104	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
CIPFEANN_01779	8.37e-185	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
CIPFEANN_01780	3.39e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
CIPFEANN_01781	4.34e-75	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
CIPFEANN_01782	9.7e-94	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
CIPFEANN_01783	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
CIPFEANN_01785	1.41e-67	-	-	-	-	-	-	-	-
CIPFEANN_01786	6.62e-66	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
CIPFEANN_01787	3.59e-26	-	-	-	-	-	-	-	-
CIPFEANN_01788	1.22e-51	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIPFEANN_01789	2.2e-62	-	-	-	-	-	-	-	-
CIPFEANN_01790	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CIPFEANN_01791	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
CIPFEANN_01792	1.23e-112	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
CIPFEANN_01793	9.09e-130	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
CIPFEANN_01794	1.62e-232	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
CIPFEANN_01795	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
CIPFEANN_01796	6.59e-124	-	-	-	-	-	-	-	-
CIPFEANN_01797	3.09e-35	-	-	-	-	-	-	-	-
CIPFEANN_01798	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CIPFEANN_01799	8.92e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
CIPFEANN_01801	1.21e-135	-	-	-	L	-	-	-	Integrase
CIPFEANN_01802	4.34e-45	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CIPFEANN_01803	7.42e-59	-	-	-	-	-	-	-	-
CIPFEANN_01805	2.36e-299	-	-	-	-	-	-	-	-
CIPFEANN_01806	2.05e-77	-	-	-	-	-	-	-	-
CIPFEANN_01807	1.99e-38	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CIPFEANN_01808	6.57e-121	-	-	-	J	-	-	-	Aminoglycoside-2''-adenylyltransferase
CIPFEANN_01809	1.85e-20	pre	-	-	D	-	-	-	plasmid recombination enzyme
CIPFEANN_01810	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
CIPFEANN_01811	5.61e-75	-	-	-	K	-	-	-	Transcriptional regulator
CIPFEANN_01812	3.02e-52	-	-	-	K	-	-	-	Transcriptional regulator
CIPFEANN_01813	7.26e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
CIPFEANN_01814	6.78e-136	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
CIPFEANN_01815	1.28e-105	-	-	-	S	-	-	-	membrane
CIPFEANN_01816	3.43e-110	-	-	-	S	-	-	-	membrane
CIPFEANN_01817	2.22e-145	-	-	-	GM	-	-	-	NAD(P)H-binding
CIPFEANN_01818	1.74e-85	-	-	-	-	-	-	-	-
CIPFEANN_01819	4.18e-168	-	-	-	F	-	-	-	glutamine amidotransferase
CIPFEANN_01820	5.28e-181	-	-	-	T	-	-	-	EAL domain
CIPFEANN_01821	7.48e-300	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
CIPFEANN_01822	1.26e-243	flp	-	-	V	-	-	-	Beta-lactamase
CIPFEANN_01823	7.15e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
CIPFEANN_01824	5.66e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
CIPFEANN_01825	1.3e-50	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
CIPFEANN_01826	1.08e-89	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
CIPFEANN_01828	1.5e-149	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
CIPFEANN_01829	4.53e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
CIPFEANN_01830	1.01e-42	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
CIPFEANN_01831	8.59e-98	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
CIPFEANN_01832	4.47e-74	-	-	-	K	-	-	-	Aminotransferase class I and II
CIPFEANN_01833	2.19e-193	-	-	-	K	-	-	-	Aminotransferase class I and II
CIPFEANN_01834	0.0	-	-	-	S	-	-	-	amidohydrolase
CIPFEANN_01835	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
CIPFEANN_01836	2.41e-111	-	-	-	F	-	-	-	NUDIX domain
CIPFEANN_01837	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIPFEANN_01838	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIPFEANN_01839	1.9e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CIPFEANN_01840	7.89e-212	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
CIPFEANN_01841	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CIPFEANN_01842	7.84e-207	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
CIPFEANN_01843	2.05e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIPFEANN_01844	1.99e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CIPFEANN_01845	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
CIPFEANN_01846	4.05e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
CIPFEANN_01847	4.79e-221	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
CIPFEANN_01848	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
CIPFEANN_01849	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
CIPFEANN_01850	3.38e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CIPFEANN_01851	1.47e-246	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CIPFEANN_01852	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_01853	4.94e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CIPFEANN_01854	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
CIPFEANN_01855	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CIPFEANN_01856	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
CIPFEANN_01857	1.73e-273	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
CIPFEANN_01858	3.8e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
CIPFEANN_01859	2.13e-76	-	-	-	M	-	-	-	Lysin motif
CIPFEANN_01860	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CIPFEANN_01861	7.6e-246	-	-	-	S	-	-	-	Helix-turn-helix domain
CIPFEANN_01862	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CIPFEANN_01863	1.67e-163	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CIPFEANN_01864	1.35e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CIPFEANN_01865	7.93e-177	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CIPFEANN_01866	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIPFEANN_01867	9.56e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
CIPFEANN_01868	1.08e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
CIPFEANN_01869	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
CIPFEANN_01870	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
CIPFEANN_01871	1.11e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
CIPFEANN_01872	1.58e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
CIPFEANN_01873	1.85e-201	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CIPFEANN_01874	2.2e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
CIPFEANN_01875	1.69e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CIPFEANN_01876	1.71e-264	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CIPFEANN_01877	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CIPFEANN_01878	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
CIPFEANN_01879	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
CIPFEANN_01880	2.14e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
CIPFEANN_01881	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CIPFEANN_01882	1.8e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
CIPFEANN_01883	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CIPFEANN_01884	1.51e-233	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
CIPFEANN_01885	7.1e-226	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CIPFEANN_01886	1.46e-120	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
CIPFEANN_01887	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
CIPFEANN_01888	1.4e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
CIPFEANN_01889	3.31e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CIPFEANN_01890	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
CIPFEANN_01891	2.61e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_01892	7.87e-146	-	-	-	-	-	-	-	-
CIPFEANN_01893	1.35e-182	-	-	-	G	-	-	-	MucBP domain
CIPFEANN_01894	7.43e-129	-	-	-	S	-	-	-	Pfam:DUF3816
CIPFEANN_01895	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
CIPFEANN_01896	1.38e-37	-	-	-	-	-	-	-	-
CIPFEANN_01897	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
CIPFEANN_01898	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIPFEANN_01901	6.85e-294	-	-	-	-	-	-	-	-
CIPFEANN_01903	2.1e-50	-	-	-	K	-	-	-	Helix-turn-helix domain
CIPFEANN_01904	2.2e-70	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
CIPFEANN_01905	3.3e-124	-	-	-	L	-	-	-	Integrase
CIPFEANN_01906	1.18e-200	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIPFEANN_01907	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CIPFEANN_01908	1.54e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
CIPFEANN_01909	4.3e-111	-	-	-	L	-	-	-	Helix-turn-helix domain
CIPFEANN_01910	1.4e-157	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CIPFEANN_01912	4.16e-200	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CIPFEANN_01913	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CIPFEANN_01914	7.45e-139	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
CIPFEANN_01915	4.63e-17	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
CIPFEANN_01916	6.47e-149	-	-	-	S	-	-	-	Membrane
CIPFEANN_01917	3.66e-124	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIPFEANN_01918	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
CIPFEANN_01919	1.77e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
CIPFEANN_01920	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
CIPFEANN_01921	1.34e-144	-	-	-	K	-	-	-	Transcriptional regulator
CIPFEANN_01924	4.21e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
CIPFEANN_01925	1.47e-223	-	-	-	-	-	-	-	-
CIPFEANN_01926	4.87e-203	-	-	-	-	-	-	-	-
CIPFEANN_01927	1.54e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
CIPFEANN_01928	1.99e-131	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIPFEANN_01929	3.08e-99	-	-	-	S	-	-	-	Fic/DOC family
CIPFEANN_01931	3.91e-40	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CIPFEANN_01932	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CIPFEANN_01933	5.72e-224	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CIPFEANN_01934	3.4e-168	ermA	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Ribosomal RNA adenine dimethylase
CIPFEANN_01940	5.66e-36	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system methyltransferase subunit()
CIPFEANN_01944	1.77e-194	-	2.7.1.95	-	J	ko:K19272,ko:K19299	-	br01600,ko00000,ko01000,ko01504	Phosphotransferase enzyme family
CIPFEANN_01945	4.49e-40	-	-	-	-	-	-	-	-
CIPFEANN_01946	1.5e-95	-	-	-	S	-	-	-	MTH538 TIR-like domain (DUF1863)
CIPFEANN_01947	4.03e-61	-	-	-	-	-	-	-	-
CIPFEANN_01948	2.74e-272	-	-	-	O	-	-	-	Subtilase family
CIPFEANN_01949	1.58e-156	-	-	-	O	-	-	-	Holliday junction DNA helicase ruvB N-terminus
CIPFEANN_01951	9.38e-91	-	-	-	O	-	-	-	Preprotein translocase subunit SecB
CIPFEANN_01953	1.17e-78	-	-	-	-	-	-	-	-
CIPFEANN_01954	5.75e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
CIPFEANN_01956	2.44e-166	-	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NAD(P)H-binding
CIPFEANN_01957	4.94e-06	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
CIPFEANN_01959	8.35e-185	-	-	-	L	-	-	-	Integrase core domain
CIPFEANN_01960	8.68e-89	-	-	-	L	-	-	-	Integrase core domain
CIPFEANN_01961	4.31e-180	-	-	-	L	-	-	-	Bacterial dnaA protein
CIPFEANN_01962	1.24e-65	-	-	-	-	-	-	-	-
CIPFEANN_01963	3.02e-276	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CIPFEANN_01964	2.4e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CIPFEANN_01965	1.36e-198	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIPFEANN_01966	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CIPFEANN_01967	4.62e-184	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIPFEANN_01968	1.52e-192	-	-	-	E	-	-	-	Glyoxalase-like domain
CIPFEANN_01970	6.56e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
CIPFEANN_01971	8.5e-208	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
CIPFEANN_01972	1.53e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CIPFEANN_01973	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CIPFEANN_01974	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
CIPFEANN_01975	7.76e-74	-	-	-	-	-	-	-	-
CIPFEANN_01976	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
CIPFEANN_01977	2.67e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CIPFEANN_01978	3.47e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
CIPFEANN_01979	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CIPFEANN_01980	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CIPFEANN_01981	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CIPFEANN_01982	1.45e-260	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CIPFEANN_01983	8.69e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CIPFEANN_01984	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CIPFEANN_01985	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CIPFEANN_01986	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CIPFEANN_01987	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
CIPFEANN_01988	1.97e-185	ylmH	-	-	S	-	-	-	S4 domain protein
CIPFEANN_01989	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
CIPFEANN_01990	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CIPFEANN_01991	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CIPFEANN_01992	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
CIPFEANN_01993	1.54e-33	-	-	-	-	-	-	-	-
CIPFEANN_01994	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CIPFEANN_01995	1.75e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CIPFEANN_01996	1.13e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
CIPFEANN_01997	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CIPFEANN_01998	6.67e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
CIPFEANN_01999	3.82e-157	-	-	-	S	-	-	-	repeat protein
CIPFEANN_02000	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CIPFEANN_02001	8.58e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIPFEANN_02002	1.08e-05	-	-	-	L	-	-	-	Helix-turn-helix domain
CIPFEANN_02003	3.1e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
CIPFEANN_02004	1.35e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CIPFEANN_02005	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CIPFEANN_02006	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIPFEANN_02007	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_02009	1.77e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CIPFEANN_02010	3.42e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
CIPFEANN_02011	2.76e-217	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
CIPFEANN_02012	5.97e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
CIPFEANN_02013	6.29e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
CIPFEANN_02014	3.73e-200	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CIPFEANN_02015	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
CIPFEANN_02016	4.83e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CIPFEANN_02017	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
CIPFEANN_02018	1.75e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CIPFEANN_02019	4.25e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
CIPFEANN_02020	3.97e-153	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CIPFEANN_02021	1.09e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CIPFEANN_02022	2.15e-298	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
CIPFEANN_02023	6.61e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
CIPFEANN_02024	1.32e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
CIPFEANN_02025	8.13e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIPFEANN_02026	3.27e-159	vanR	-	-	K	-	-	-	response regulator
CIPFEANN_02027	5.47e-261	hpk31	-	-	T	-	-	-	Histidine kinase
CIPFEANN_02028	4.95e-195	-	-	-	E	-	-	-	AzlC protein
CIPFEANN_02029	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
CIPFEANN_02030	4.71e-109	-	-	-	-	-	-	-	-
CIPFEANN_02032	6.5e-238	-	-	-	M	-	-	-	Glycosyl transferase
CIPFEANN_02033	3.16e-169	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
CIPFEANN_02034	4.6e-184	-	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
CIPFEANN_02035	7.99e-221	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
CIPFEANN_02036	2.46e-81	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
CIPFEANN_02037	6.22e-112	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
CIPFEANN_02038	8.75e-81	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CIPFEANN_02039	3.4e-126	-	-	-	S	-	-	-	Chloramphenicol phosphotransferase-like protein
CIPFEANN_02040	6.27e-216	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
CIPFEANN_02042	4.51e-06	bamA	-	-	GM	ko:K07277,ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029	domain, Protein
CIPFEANN_02043	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
CIPFEANN_02044	2.72e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
CIPFEANN_02045	4.82e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CIPFEANN_02046	4.22e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_02047	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_02048	1.18e-50	-	-	-	-	-	-	-	-
CIPFEANN_02049	7.21e-35	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
CIPFEANN_02050	7.05e-101	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CIPFEANN_02051	2.6e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIPFEANN_02052	1.47e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
CIPFEANN_02054	1.03e-59	yrvD	-	-	S	-	-	-	Pfam:DUF1049
CIPFEANN_02055	4.68e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
CIPFEANN_02056	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
CIPFEANN_02057	1.01e-28	-	-	-	-	-	-	-	-
CIPFEANN_02058	3.46e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CIPFEANN_02059	1.2e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
CIPFEANN_02060	9.59e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
CIPFEANN_02061	1.89e-55	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
CIPFEANN_02062	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
CIPFEANN_02063	5.77e-121	-	-	-	P	-	-	-	Cadmium resistance transporter
CIPFEANN_02064	5.63e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIPFEANN_02065	5.58e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CIPFEANN_02066	3.16e-233	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CIPFEANN_02067	3.13e-164	-	-	-	M	-	-	-	PFAM NLP P60 protein
CIPFEANN_02069	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIPFEANN_02071	8.9e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
CIPFEANN_02072	7.37e-275	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
CIPFEANN_02073	3.98e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CIPFEANN_02074	2.7e-112	-	-	-	L	-	-	-	Transposase
CIPFEANN_02078	5.41e-236	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
CIPFEANN_02079	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CIPFEANN_02080	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
CIPFEANN_02081	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
CIPFEANN_02082	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CIPFEANN_02083	9.92e-110	-	-	-	-	-	-	-	-
CIPFEANN_02093	2.01e-13	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CIPFEANN_02097	1.15e-279	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
CIPFEANN_02098	2.54e-136	-	-	-	S	-	-	-	Protein of unknown function DUF262
CIPFEANN_02099	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
CIPFEANN_02100	8.78e-140	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
CIPFEANN_02101	1.78e-94	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
CIPFEANN_02102	6.74e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
CIPFEANN_02103	1.25e-129	-	-	-	L	-	-	-	DEAD-like helicases superfamily
CIPFEANN_02105	5.68e-95	-	-	-	K	-	-	-	DNA-templated transcription, initiation
CIPFEANN_02106	7.27e-38	-	-	-	-	-	-	-	-
CIPFEANN_02107	1.66e-58	-	-	-	-	-	-	-	-
CIPFEANN_02108	3.25e-273	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
CIPFEANN_02109	1.51e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
CIPFEANN_02110	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
CIPFEANN_02111	3.05e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CIPFEANN_02112	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
CIPFEANN_02113	1.77e-61	-	-	-	S	-	-	-	VRR_NUC
CIPFEANN_02114	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
CIPFEANN_02115	1.15e-109	-	-	-	-	-	-	-	-
CIPFEANN_02116	2.4e-130	-	-	-	-	-	-	-	-
CIPFEANN_02117	2.66e-289	-	-	-	KL	-	-	-	DNA methylase
CIPFEANN_02118	5.72e-144	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CIPFEANN_02119	2.4e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
CIPFEANN_02120	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
CIPFEANN_02121	2.37e-310	-	-	-	S	-	-	-	Phage portal protein
CIPFEANN_02122	2.7e-155	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
CIPFEANN_02123	2.92e-278	-	-	-	S	-	-	-	Phage capsid family
CIPFEANN_02124	1.78e-56	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
CIPFEANN_02125	1.06e-87	-	-	-	S	-	-	-	Phage head-tail joining protein
CIPFEANN_02126	1.99e-90	-	-	-	S	-	-	-	Bacteriophage holin family
CIPFEANN_02127	2.15e-184	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CIPFEANN_02128	1.03e-37	-	-	-	-	-	-	-	-
CIPFEANN_02129	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
CIPFEANN_02130	0.0	-	-	-	L	-	-	-	Recombinase
CIPFEANN_02132	1.51e-146	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
CIPFEANN_02133	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIPFEANN_02134	5.06e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
CIPFEANN_02135	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIPFEANN_02136	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CIPFEANN_02137	3.22e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIPFEANN_02138	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
CIPFEANN_02139	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CIPFEANN_02140	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
CIPFEANN_02141	8.91e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CIPFEANN_02142	3.91e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CIPFEANN_02143	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
CIPFEANN_02144	4.46e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
CIPFEANN_02145	1.15e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
CIPFEANN_02146	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CIPFEANN_02147	2.41e-264	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
CIPFEANN_02148	3.28e-156	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CIPFEANN_02149	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CIPFEANN_02150	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
CIPFEANN_02151	1.18e-133	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
CIPFEANN_02152	4.15e-228	tetB	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major facilitator superfamily
CIPFEANN_02153	1.15e-29	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase type I activity
CIPFEANN_02154	1.15e-162	-	-	-	L	ko:K07498	-	ko00000	DDE domain
CIPFEANN_02155	1.65e-128	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
CIPFEANN_02156	1.05e-91	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIPFEANN_02157	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
CIPFEANN_02159	2.12e-105	-	-	-	L	-	-	-	Integrase
CIPFEANN_02160	1.13e-22	-	-	-	M	-	-	-	KxYKxGKxW signal domain protein
CIPFEANN_02161	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CIPFEANN_02162	1.89e-80	-	-	-	-	-	-	-	-
CIPFEANN_02163	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIPFEANN_02164	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CIPFEANN_02165	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CIPFEANN_02166	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CIPFEANN_02167	1.14e-152	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
CIPFEANN_02168	9.72e-159	-	-	-	-	-	-	-	-
CIPFEANN_02171	1.4e-34	-	-	-	K	-	-	-	TRANSCRIPTIONal
CIPFEANN_02172	3.61e-53	yju3	-	-	I	-	-	-	Serine aminopeptidase, S33
CIPFEANN_02174	1.56e-102	pncA	-	-	Q	-	-	-	Isochorismatase family
CIPFEANN_02175	1.5e-289	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIPFEANN_02176	1.76e-143	-	-	-	F	-	-	-	NUDIX domain
CIPFEANN_02177	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
CIPFEANN_02178	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CIPFEANN_02179	6.12e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CIPFEANN_02180	1.43e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIPFEANN_02181	9.73e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIPFEANN_02182	1.23e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIPFEANN_02183	4.57e-30	-	-	-	L	-	-	-	Replication initiation factor
CIPFEANN_02185	4.65e-110	vatD	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	acetyltransferase'
CIPFEANN_02189	2.99e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CIPFEANN_02190	1.09e-250	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CIPFEANN_02191	7.34e-226	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CIPFEANN_02192	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
CIPFEANN_02193	9.4e-122	-	-	-	S	-	-	-	PFAM Archaeal ATPase
CIPFEANN_02194	3.81e-62	-	-	-	-	-	-	-	-
CIPFEANN_02196	3.44e-47	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
CIPFEANN_02197	1.52e-205	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
CIPFEANN_02198	2.64e-315	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
CIPFEANN_02199	1.16e-114	XK27_07210	-	-	S	-	-	-	B3 4 domain
CIPFEANN_02200	8.65e-119	-	-	-	-	-	-	-	-
CIPFEANN_02201	4.09e-61	pnb	-	-	C	-	-	-	nitroreductase
CIPFEANN_02202	2.3e-68	pnb	-	-	C	-	-	-	nitroreductase
CIPFEANN_02203	6.92e-96	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
CIPFEANN_02204	1.93e-216	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
CIPFEANN_02205	6.47e-214	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
CIPFEANN_02206	1.53e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
CIPFEANN_02207	1.05e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
CIPFEANN_02208	4.9e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
CIPFEANN_02209	5.18e-27	-	-	-	-	-	-	-	-
CIPFEANN_02210	6.48e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
CIPFEANN_02211	2.25e-105	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
CIPFEANN_02212	8.22e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
CIPFEANN_02213	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
CIPFEANN_02214	1.86e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CIPFEANN_02215	1.25e-136	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
CIPFEANN_02216	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
CIPFEANN_02217	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
CIPFEANN_02218	8.67e-294	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
CIPFEANN_02220	2.09e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CIPFEANN_02221	2.02e-72	-	-	-	-	-	-	-	-
CIPFEANN_02222	4.94e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
CIPFEANN_02223	1.11e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
CIPFEANN_02224	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
CIPFEANN_02225	3.98e-280	arcT	-	-	E	-	-	-	Aminotransferase
CIPFEANN_02226	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
CIPFEANN_02227	0.0	potE	-	-	E	-	-	-	Amino Acid
CIPFEANN_02228	7.47e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
CIPFEANN_02229	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
CIPFEANN_02230	2.53e-42	-	-	-	-	-	-	-	-
CIPFEANN_02231	2.02e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
CIPFEANN_02232	2.23e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
CIPFEANN_02233	1.55e-222	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
CIPFEANN_02234	9.45e-152	-	-	-	M	-	-	-	Bacterial sugar transferase
CIPFEANN_02235	2.78e-275	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
CIPFEANN_02236	6.68e-302	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
CIPFEANN_02237	5.68e-190	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
CIPFEANN_02238	1.01e-167	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
CIPFEANN_02239	5.69e-149	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
CIPFEANN_02241	5.13e-126	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
CIPFEANN_02242	6.08e-235	cps3F	-	-	-	-	-	-	-
CIPFEANN_02243	4e-109	-	-	-	M	-	-	-	biosynthesis protein
CIPFEANN_02245	3.96e-54	-	-	-	M	-	-	-	KxYKxGKxW signal domain protein
CIPFEANN_02246	1.07e-154	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
CIPFEANN_02247	4.96e-40	-	-	-	-	-	-	-	-