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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
COCFMAFH_00002	2.53e-55	-	-	-	-	-	-	-	-
COCFMAFH_00003	4.66e-201	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
COCFMAFH_00007	3.8e-13	-	-	-	-	-	-	-	-
COCFMAFH_00009	1.84e-70	-	-	-	L	-	-	-	Resolvase, N terminal domain
COCFMAFH_00010	9.05e-174	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
COCFMAFH_00011	1.65e-215	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
COCFMAFH_00012	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
COCFMAFH_00013	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COCFMAFH_00014	1.09e-62	-	-	-	-	-	-	-	-
COCFMAFH_00018	1.04e-101	-	-	-	S	ko:K17882	-	ko00000,ko01000,ko01504	KNTase C-terminal domain
COCFMAFH_00019	4.67e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
COCFMAFH_00020	7.45e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
COCFMAFH_00021	7.22e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COCFMAFH_00022	4.61e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
COCFMAFH_00023	2.47e-241	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
COCFMAFH_00024	2.69e-79	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
COCFMAFH_00027	3.8e-61	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
COCFMAFH_00028	7.66e-42	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
COCFMAFH_00029	9.73e-146	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
COCFMAFH_00030	1.01e-120	dpsB	-	-	P	-	-	-	Belongs to the Dps family
COCFMAFH_00031	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
COCFMAFH_00032	9.18e-252	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
COCFMAFH_00033	1.78e-136	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
COCFMAFH_00034	6.1e-104	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
COCFMAFH_00037	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
COCFMAFH_00038	1.38e-65	-	-	-	-	-	-	-	-
COCFMAFH_00039	4.47e-292	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
COCFMAFH_00040	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COCFMAFH_00041	1.58e-245	bamA	-	-	GM	ko:K07277,ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029	domain, Protein
COCFMAFH_00042	4.48e-107	-	-	-	L	-	-	-	Integrase
COCFMAFH_00048	2.93e-290	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
COCFMAFH_00050	1.95e-35	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
COCFMAFH_00051	3.17e-290	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
COCFMAFH_00054	4.83e-135	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COCFMAFH_00056	2.2e-28	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
COCFMAFH_00061	1.06e-29	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COCFMAFH_00062	3.05e-57	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
COCFMAFH_00070	1.47e-14	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COCFMAFH_00072	1.79e-29	-	-	-	-	-	-	-	-
COCFMAFH_00080	7.7e-17	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
COCFMAFH_00086	1.17e-90	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
COCFMAFH_00090	2.01e-13	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COCFMAFH_00091	1.39e-118	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COCFMAFH_00092	5.58e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
COCFMAFH_00093	1.34e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COCFMAFH_00094	2.33e-202	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COCFMAFH_00095	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COCFMAFH_00096	1.13e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
COCFMAFH_00097	5.77e-128	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
COCFMAFH_00098	4.36e-287	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
COCFMAFH_00099	1.62e-157	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
COCFMAFH_00100	4.01e-216	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
COCFMAFH_00101	3.35e-59	-	-	-	S	-	-	-	Pfam:DUF59
COCFMAFH_00102	4.48e-90	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
COCFMAFH_00103	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
COCFMAFH_00110	2.8e-81	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
COCFMAFH_00111	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
COCFMAFH_00112	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
COCFMAFH_00133	4.98e-49	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
COCFMAFH_00134	4.47e-74	-	-	-	K	-	-	-	Aminotransferase class I and II
COCFMAFH_00135	2.19e-193	-	-	-	K	-	-	-	Aminotransferase class I and II
COCFMAFH_00136	0.0	-	-	-	S	-	-	-	amidohydrolase
COCFMAFH_00138	1.65e-206	-	-	-	S	-	-	-	reductase
COCFMAFH_00139	4.4e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
COCFMAFH_00140	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
COCFMAFH_00141	7.33e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
COCFMAFH_00142	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COCFMAFH_00143	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
COCFMAFH_00144	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COCFMAFH_00145	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COCFMAFH_00146	2.55e-169	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
COCFMAFH_00147	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COCFMAFH_00148	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COCFMAFH_00149	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
COCFMAFH_00150	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COCFMAFH_00151	1.41e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COCFMAFH_00152	1.97e-105	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
COCFMAFH_00153	9.78e-14	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
COCFMAFH_00154	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
COCFMAFH_00155	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COCFMAFH_00156	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COCFMAFH_00157	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COCFMAFH_00158	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
COCFMAFH_00159	5.69e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COCFMAFH_00160	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COCFMAFH_00161	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
COCFMAFH_00162	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
COCFMAFH_00163	6.04e-307	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
COCFMAFH_00164	5.34e-269	yttB	-	-	EGP	-	-	-	Major Facilitator
COCFMAFH_00165	3.85e-72	-	-	-	-	-	-	-	-
COCFMAFH_00166	1.46e-207	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
COCFMAFH_00167	1.88e-11	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
COCFMAFH_00168	2.01e-161	-	-	-	O	-	-	-	Bacterial dnaA protein
COCFMAFH_00169	5.35e-271	-	-	-	L	-	-	-	Integrase core domain
COCFMAFH_00172	1.51e-300	-	-	-	L	-	-	-	Integrase core domain
COCFMAFH_00173	7.12e-171	-	-	-	O	-	-	-	Bacterial dnaA protein
COCFMAFH_00174	7.92e-221	-	-	-	-	-	-	-	-
COCFMAFH_00175	6.34e-95	-	-	-	-	-	-	-	-
COCFMAFH_00176	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
COCFMAFH_00177	3.11e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
COCFMAFH_00179	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
COCFMAFH_00180	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COCFMAFH_00181	3.85e-159	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COCFMAFH_00183	4.65e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
COCFMAFH_00184	9.59e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
COCFMAFH_00185	1.2e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
COCFMAFH_00186	5.9e-48	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
COCFMAFH_00187	5.28e-29	-	-	-	-	-	-	-	-
COCFMAFH_00188	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
COCFMAFH_00189	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
COCFMAFH_00190	3.52e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
COCFMAFH_00191	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
COCFMAFH_00192	7.54e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
COCFMAFH_00193	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
COCFMAFH_00194	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
COCFMAFH_00195	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COCFMAFH_00196	3.51e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
COCFMAFH_00197	3.4e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
COCFMAFH_00198	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
COCFMAFH_00199	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
COCFMAFH_00200	9.21e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
COCFMAFH_00201	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
COCFMAFH_00202	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COCFMAFH_00203	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COCFMAFH_00204	2.94e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
COCFMAFH_00205	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COCFMAFH_00206	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COCFMAFH_00207	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COCFMAFH_00208	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
COCFMAFH_00209	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
COCFMAFH_00210	2.44e-20	-	-	-	-	-	-	-	-
COCFMAFH_00211	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COCFMAFH_00212	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COCFMAFH_00213	4.82e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COCFMAFH_00214	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
COCFMAFH_00215	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
COCFMAFH_00216	1.46e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COCFMAFH_00217	1.79e-121	-	-	-	-	-	-	-	-
COCFMAFH_00218	6.47e-172	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COCFMAFH_00219	7.86e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
COCFMAFH_00220	1.04e-08	-	-	-	K	-	-	-	transcriptional
COCFMAFH_00222	1.84e-52	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
COCFMAFH_00228	9.99e-56	-	-	-	S	ko:K06919	-	ko00000	DNA primase
COCFMAFH_00229	1.13e-18	-	-	-	-	-	-	-	-
COCFMAFH_00230	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
COCFMAFH_00231	1.77e-230	yueF	-	-	S	-	-	-	AI-2E family transporter
COCFMAFH_00232	7.41e-163	-	-	-	-	-	-	-	-
COCFMAFH_00233	9.52e-72	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
COCFMAFH_00234	7.7e-277	isp	-	-	L	-	-	-	Transposase
COCFMAFH_00235	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
COCFMAFH_00236	5.21e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COCFMAFH_00237	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
COCFMAFH_00238	2.95e-41	-	-	-	S	ko:K19279	-	ko00000,ko01000,ko01504	Domain of unknown function (DUF4111)
COCFMAFH_00239	5.9e-82	-	-	-	S	ko:K19279	-	ko00000,ko01000,ko01504	Domain of unknown function (DUF4111)
COCFMAFH_00240	5.95e-238	-	-	-	L	-	-	-	PFAM Integrase catalytic region
COCFMAFH_00241	1.91e-144	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
COCFMAFH_00242	3.73e-94	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
COCFMAFH_00243	1.44e-90	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
COCFMAFH_00244	3.45e-87	-	-	-	P	-	-	-	Cadmium resistance transporter
COCFMAFH_00245	1.06e-96	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
COCFMAFH_00246	1.08e-147	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
COCFMAFH_00247	9.15e-72	-	-	-	E	ko:K04031	-	ko00000	BMC
COCFMAFH_00248	2.06e-277	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COCFMAFH_00249	4.33e-259	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
COCFMAFH_00250	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
COCFMAFH_00251	1.68e-103	pduO	-	-	S	-	-	-	Haem-degrading
COCFMAFH_00252	6e-136	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
COCFMAFH_00253	5.63e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
COCFMAFH_00254	1.25e-103	-	-	-	S	-	-	-	Putative propanediol utilisation
COCFMAFH_00255	1.98e-148	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
COCFMAFH_00256	3.65e-53	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
COCFMAFH_00257	4.63e-75	-	-	-	CQ	-	-	-	BMC
COCFMAFH_00258	5.18e-59	pduH	-	-	S	-	-	-	Dehydratase medium subunit
COCFMAFH_00259	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
COCFMAFH_00260	3.09e-97	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
COCFMAFH_00261	5e-162	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
COCFMAFH_00262	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
COCFMAFH_00263	3.41e-170	pduB	-	-	E	-	-	-	BMC
COCFMAFH_00264	2.33e-50	-	-	-	CQ	-	-	-	BMC
COCFMAFH_00265	1.69e-202	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COCFMAFH_00266	4.02e-177	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
COCFMAFH_00267	2.7e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
COCFMAFH_00268	4.54e-119	-	-	-	-	-	-	-	-
COCFMAFH_00269	8.33e-161	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
COCFMAFH_00270	8.61e-214	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
COCFMAFH_00271	1.5e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
COCFMAFH_00272	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
COCFMAFH_00273	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
COCFMAFH_00274	3.16e-114	-	-	-	GM	-	-	-	epimerase
COCFMAFH_00275	1.39e-198	-	-	-	V	-	-	-	(ABC) transporter
COCFMAFH_00276	1.37e-306	yhdP	-	-	S	-	-	-	Transporter associated domain
COCFMAFH_00277	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
COCFMAFH_00278	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
COCFMAFH_00279	2.64e-246	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
COCFMAFH_00280	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COCFMAFH_00281	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COCFMAFH_00282	4.58e-169	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
COCFMAFH_00283	1e-50	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COCFMAFH_00284	4.93e-35	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COCFMAFH_00289	1.08e-124	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COCFMAFH_00290	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
COCFMAFH_00291	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
COCFMAFH_00292	5.69e-188	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
COCFMAFH_00293	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COCFMAFH_00294	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COCFMAFH_00295	9.61e-137	-	-	-	-	-	-	-	-
COCFMAFH_00296	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COCFMAFH_00297	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
COCFMAFH_00298	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
COCFMAFH_00299	8.46e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COCFMAFH_00300	3.55e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
COCFMAFH_00301	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
COCFMAFH_00302	6.77e-216	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
COCFMAFH_00303	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COCFMAFH_00304	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
COCFMAFH_00305	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
COCFMAFH_00306	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COCFMAFH_00307	7.48e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
COCFMAFH_00308	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COCFMAFH_00309	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COCFMAFH_00310	5.17e-70	-	-	-	-	-	-	-	-
COCFMAFH_00311	0.0	oatA	-	-	I	-	-	-	Acyltransferase
COCFMAFH_00312	3.7e-106	-	-	-	K	-	-	-	Transcriptional regulator
COCFMAFH_00313	9.84e-194	-	-	-	S	-	-	-	Cof-like hydrolase
COCFMAFH_00314	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
COCFMAFH_00316	7.74e-172	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
COCFMAFH_00317	0.0	yclK	-	-	T	-	-	-	Histidine kinase
COCFMAFH_00318	2.71e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
COCFMAFH_00319	2.15e-138	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
COCFMAFH_00320	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
COCFMAFH_00321	2.49e-39	-	-	-	-	-	-	-	-
COCFMAFH_00322	1.5e-276	xylR	-	-	GK	-	-	-	ROK family
COCFMAFH_00324	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
COCFMAFH_00325	3.69e-114	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
COCFMAFH_00326	4.92e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COCFMAFH_00327	7.38e-232	-	-	-	-	-	-	-	-
COCFMAFH_00328	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COCFMAFH_00329	4.57e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
COCFMAFH_00330	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
COCFMAFH_00331	4.78e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COCFMAFH_00332	5.37e-248	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
COCFMAFH_00333	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COCFMAFH_00334	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COCFMAFH_00335	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COCFMAFH_00336	2.23e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COCFMAFH_00337	7.43e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
COCFMAFH_00338	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COCFMAFH_00339	1.61e-271	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COCFMAFH_00340	3.65e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COCFMAFH_00341	9.77e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
COCFMAFH_00342	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
COCFMAFH_00343	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
COCFMAFH_00344	6.76e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
COCFMAFH_00345	4.67e-301	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
COCFMAFH_00346	4.34e-121	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
COCFMAFH_00347	6.4e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
COCFMAFH_00348	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COCFMAFH_00349	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COCFMAFH_00350	1.95e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COCFMAFH_00351	5.23e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COCFMAFH_00352	6.04e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
COCFMAFH_00353	1.04e-174	-	-	-	K	-	-	-	LysR substrate binding domain
COCFMAFH_00355	3.3e-173	-	-	-	M	-	-	-	PFAM NLP P60 protein
COCFMAFH_00356	3.16e-233	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
COCFMAFH_00357	5.58e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
COCFMAFH_00358	5.63e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_00359	3.34e-120	-	-	-	P	-	-	-	Cadmium resistance transporter
COCFMAFH_00360	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
COCFMAFH_00361	1.39e-44	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
COCFMAFH_00362	7.25e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
COCFMAFH_00363	4.38e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
COCFMAFH_00364	1.8e-167	yceF	-	-	P	ko:K05794	-	ko00000	membrane
COCFMAFH_00365	3.32e-211	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
COCFMAFH_00366	2.35e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
COCFMAFH_00367	0.0	-	-	-	L	-	-	-	Transposase
COCFMAFH_00368	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COCFMAFH_00369	6.8e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
COCFMAFH_00370	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
COCFMAFH_00371	3.98e-304	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
COCFMAFH_00372	3.39e-33	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
COCFMAFH_00373	3.18e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
COCFMAFH_00374	1.77e-56	-	-	-	-	-	-	-	-
COCFMAFH_00375	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COCFMAFH_00376	1.16e-263	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
COCFMAFH_00377	2.56e-188	-	-	-	S	-	-	-	Alpha beta hydrolase
COCFMAFH_00378	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COCFMAFH_00379	4.75e-132	-	-	-	-	-	-	-	-
COCFMAFH_00381	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
COCFMAFH_00382	1.08e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
COCFMAFH_00383	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
COCFMAFH_00384	1.61e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COCFMAFH_00385	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
COCFMAFH_00386	1.45e-55	-	-	-	-	-	-	-	-
COCFMAFH_00387	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
COCFMAFH_00388	3.85e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COCFMAFH_00389	4.29e-119	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
COCFMAFH_00390	0.0	-	-	-	EGP	-	-	-	Major Facilitator
COCFMAFH_00391	1.25e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
COCFMAFH_00392	9.95e-303	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
COCFMAFH_00393	8.28e-135	-	-	-	V	-	-	-	VanZ like family
COCFMAFH_00394	7.03e-33	-	-	-	-	-	-	-	-
COCFMAFH_00395	1.01e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
COCFMAFH_00396	3.77e-102	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COCFMAFH_00397	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
COCFMAFH_00398	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
COCFMAFH_00399	7.77e-198	yeaE	-	-	S	-	-	-	Aldo keto
COCFMAFH_00400	4.57e-137	-	-	-	M	-	-	-	LysM domain protein
COCFMAFH_00401	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
COCFMAFH_00402	1.36e-148	-	-	-	M	-	-	-	LysM domain protein
COCFMAFH_00403	3.48e-192	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
COCFMAFH_00404	3.94e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COCFMAFH_00405	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
COCFMAFH_00406	1.63e-312	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
COCFMAFH_00407	1.74e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COCFMAFH_00418	6.48e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
COCFMAFH_00419	2.25e-105	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
COCFMAFH_00420	2.87e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
COCFMAFH_00421	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
COCFMAFH_00422	1.86e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
COCFMAFH_00423	1.25e-136	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
COCFMAFH_00424	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
COCFMAFH_00425	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
COCFMAFH_00426	7.11e-293	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
COCFMAFH_00428	2.09e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COCFMAFH_00429	2.02e-72	-	-	-	-	-	-	-	-
COCFMAFH_00430	4.94e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
COCFMAFH_00431	1.58e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
COCFMAFH_00432	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
COCFMAFH_00433	3.98e-280	arcT	-	-	E	-	-	-	Aminotransferase
COCFMAFH_00434	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
COCFMAFH_00435	0.0	potE	-	-	E	-	-	-	Amino Acid
COCFMAFH_00436	7.47e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
COCFMAFH_00437	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
COCFMAFH_00438	1.25e-42	-	-	-	-	-	-	-	-
COCFMAFH_00439	2.02e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
COCFMAFH_00440	2.23e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
COCFMAFH_00441	9.73e-226	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
COCFMAFH_00442	6.93e-154	-	-	-	M	-	-	-	Bacterial sugar transferase
COCFMAFH_00443	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
COCFMAFH_00444	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
COCFMAFH_00445	4.46e-46	-	-	-	-	-	-	-	-
COCFMAFH_00446	5.29e-184	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
COCFMAFH_00447	4.44e-91	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
COCFMAFH_00448	4.47e-95	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
COCFMAFH_00449	2.56e-152	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
COCFMAFH_00450	1.41e-98	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
COCFMAFH_00451	3.91e-305	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
COCFMAFH_00452	2.77e-223	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
COCFMAFH_00453	6.56e-174	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
COCFMAFH_00454	6.66e-246	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
COCFMAFH_00455	3.85e-75	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
COCFMAFH_00456	2.78e-302	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
COCFMAFH_00457	7.19e-155	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
COCFMAFH_00458	4.42e-130	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
COCFMAFH_00459	8.36e-59	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
COCFMAFH_00460	2.23e-157	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
COCFMAFH_00461	5.52e-117	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
COCFMAFH_00462	1.39e-138	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
COCFMAFH_00463	1.32e-220	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
COCFMAFH_00464	1.43e-123	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
COCFMAFH_00465	7.98e-166	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
COCFMAFH_00466	1.34e-182	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
COCFMAFH_00467	8.16e-165	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
COCFMAFH_00468	1.72e-90	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
COCFMAFH_00469	9.45e-101	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
COCFMAFH_00470	1.2e-245	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
COCFMAFH_00471	3.17e-138	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
COCFMAFH_00472	8.37e-184	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
COCFMAFH_00473	1.64e-258	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
COCFMAFH_00474	4.9e-216	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
COCFMAFH_00475	1.72e-102	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
COCFMAFH_00476	1.98e-147	-	-	-	M	-	-	-	PFAM NLP P60 protein
COCFMAFH_00477	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COCFMAFH_00478	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COCFMAFH_00479	4.77e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
COCFMAFH_00480	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
COCFMAFH_00481	2.22e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COCFMAFH_00482	1.79e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
COCFMAFH_00483	3.89e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COCFMAFH_00484	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
COCFMAFH_00485	7.99e-293	-	-	-	V	-	-	-	MatE
COCFMAFH_00486	0.0	potE	-	-	E	-	-	-	Amino Acid
COCFMAFH_00487	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
COCFMAFH_00488	1.38e-155	csrR	-	-	K	-	-	-	response regulator
COCFMAFH_00489	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
COCFMAFH_00490	4.8e-128	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
COCFMAFH_00491	3.95e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
COCFMAFH_00492	1.1e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
COCFMAFH_00493	2.69e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COCFMAFH_00494	3.6e-146	yqeK	-	-	H	-	-	-	Hydrolase, HD family
COCFMAFH_00495	2.43e-158	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COCFMAFH_00496	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
COCFMAFH_00497	9.01e-278	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
COCFMAFH_00498	3.17e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
COCFMAFH_00499	2.23e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COCFMAFH_00500	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
COCFMAFH_00501	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COCFMAFH_00502	9.62e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
COCFMAFH_00503	3.31e-275	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
COCFMAFH_00504	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COCFMAFH_00505	5.91e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COCFMAFH_00506	2.74e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COCFMAFH_00507	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COCFMAFH_00508	3.26e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
COCFMAFH_00509	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
COCFMAFH_00510	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
COCFMAFH_00511	8.55e-46	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
COCFMAFH_00512	7.39e-64	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
COCFMAFH_00513	1.63e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COCFMAFH_00514	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
COCFMAFH_00515	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
COCFMAFH_00516	3.46e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
COCFMAFH_00517	2.32e-233	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
COCFMAFH_00518	5.88e-126	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
COCFMAFH_00519	6.79e-183	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
COCFMAFH_00520	1.43e-311	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
COCFMAFH_00521	1.87e-41	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
COCFMAFH_00522	3.31e-37	-	-	-	S	-	-	-	YSIRK type signal peptide
COCFMAFH_00523	1.85e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COCFMAFH_00524	6.64e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
COCFMAFH_00525	2.7e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_00526	4.99e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
COCFMAFH_00528	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COCFMAFH_00529	0.0	yhaN	-	-	L	-	-	-	AAA domain
COCFMAFH_00530	2.62e-282	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
COCFMAFH_00531	3.75e-77	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
COCFMAFH_00532	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
COCFMAFH_00533	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
COCFMAFH_00534	2.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
COCFMAFH_00535	3.88e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
COCFMAFH_00537	9.76e-45	-	-	-	-	-	-	-	-
COCFMAFH_00538	9.3e-61	-	-	-	-	-	-	-	-
COCFMAFH_00539	1.62e-277	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
COCFMAFH_00540	2.97e-136	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
COCFMAFH_00541	8.17e-285	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
COCFMAFH_00542	9.63e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
COCFMAFH_00543	4.71e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
COCFMAFH_00544	6.82e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COCFMAFH_00545	2.47e-88	-	-	-	-	-	-	-	-
COCFMAFH_00548	8.16e-193	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
COCFMAFH_00549	2.53e-53	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
COCFMAFH_00556	1.04e-48	-	-	-	LM	-	-	-	gp58-like protein
COCFMAFH_00557	3.11e-173	-	-	-	M	-	-	-	Prophage endopeptidase tail
COCFMAFH_00558	1.06e-101	-	-	-	S	-	-	-	Phage tail protein
COCFMAFH_00559	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
COCFMAFH_00561	1.76e-98	-	-	-	S	-	-	-	Phage tail tube protein
COCFMAFH_00563	1.32e-40	-	-	-	S	-	-	-	exonuclease activity
COCFMAFH_00565	5.79e-54	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
COCFMAFH_00566	1.05e-199	-	-	-	S	-	-	-	Phage capsid family
COCFMAFH_00567	8.7e-138	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
COCFMAFH_00568	7.31e-268	-	-	-	S	-	-	-	Phage portal protein
COCFMAFH_00569	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
COCFMAFH_00570	1.43e-83	-	-	-	L	-	-	-	Phage terminase, small subunit
COCFMAFH_00571	3.52e-84	-	-	-	L	-	-	-	HNH nucleases
COCFMAFH_00574	8.71e-100	-	-	-	-	-	-	-	-
COCFMAFH_00577	3.97e-27	-	-	-	-	-	-	-	-
COCFMAFH_00580	3e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
COCFMAFH_00582	7.26e-55	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
COCFMAFH_00583	1.08e-35	-	-	-	L	-	-	-	DnaD domain protein
COCFMAFH_00584	3.55e-14	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
COCFMAFH_00585	2.71e-66	-	-	-	S	-	-	-	ERF superfamily
COCFMAFH_00591	7.9e-155	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
COCFMAFH_00592	2.3e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COCFMAFH_00593	2.92e-31	-	-	-	S	-	-	-	sequence-specific DNA binding
COCFMAFH_00595	1.73e-26	-	-	-	-	-	-	-	-
COCFMAFH_00596	1.48e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
COCFMAFH_00598	1.21e-130	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COCFMAFH_00600	9.17e-59	-	-	-	-	-	-	-	-
COCFMAFH_00601	1.05e-153	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
COCFMAFH_00602	1.52e-43	-	-	-	-	-	-	-	-
COCFMAFH_00603	2.32e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COCFMAFH_00604	8.42e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
COCFMAFH_00605	1.26e-145	-	-	-	-	-	-	-	-
COCFMAFH_00606	6.18e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
COCFMAFH_00607	1.29e-223	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COCFMAFH_00608	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COCFMAFH_00609	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COCFMAFH_00610	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
COCFMAFH_00611	4.12e-164	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
COCFMAFH_00612	1.34e-155	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
COCFMAFH_00613	1.66e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
COCFMAFH_00614	2.63e-53	-	-	-	-	-	-	-	-
COCFMAFH_00615	0.0	ydaO	-	-	E	-	-	-	amino acid
COCFMAFH_00616	0.0	-	-	-	E	-	-	-	amino acid
COCFMAFH_00617	3.11e-106	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
COCFMAFH_00618	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COCFMAFH_00619	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COCFMAFH_00621	3.84e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COCFMAFH_00622	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
COCFMAFH_00623	1.39e-231	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COCFMAFH_00624	1.41e-285	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COCFMAFH_00625	1.82e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
COCFMAFH_00626	3.49e-175	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COCFMAFH_00627	6.3e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COCFMAFH_00628	5.14e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COCFMAFH_00629	8.63e-253	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COCFMAFH_00630	3.02e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
COCFMAFH_00631	1.27e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
COCFMAFH_00632	1.81e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
COCFMAFH_00633	1.21e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COCFMAFH_00634	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COCFMAFH_00635	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COCFMAFH_00636	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
COCFMAFH_00637	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
COCFMAFH_00638	1.68e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
COCFMAFH_00639	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
COCFMAFH_00640	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COCFMAFH_00641	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COCFMAFH_00642	5.46e-297	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
COCFMAFH_00643	2.37e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
COCFMAFH_00644	1.83e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COCFMAFH_00645	4.23e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COCFMAFH_00646	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
COCFMAFH_00647	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COCFMAFH_00648	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
COCFMAFH_00649	8.38e-233	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COCFMAFH_00650	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
COCFMAFH_00651	5.9e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
COCFMAFH_00652	7.51e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
COCFMAFH_00653	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
COCFMAFH_00654	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
COCFMAFH_00655	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COCFMAFH_00656	9.18e-140	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
COCFMAFH_00657	1.79e-84	-	-	-	-	-	-	-	-
COCFMAFH_00658	1.13e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COCFMAFH_00659	5.24e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COCFMAFH_00660	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
COCFMAFH_00661	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COCFMAFH_00662	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COCFMAFH_00663	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COCFMAFH_00664	2.39e-253	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
COCFMAFH_00666	4.78e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
COCFMAFH_00668	7.92e-76	-	-	-	-	-	-	-	-
COCFMAFH_00669	4.65e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
COCFMAFH_00670	1.66e-165	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COCFMAFH_00671	4.8e-72	-	-	-	-	-	-	-	-
COCFMAFH_00672	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COCFMAFH_00673	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COCFMAFH_00674	8.52e-152	-	-	-	G	-	-	-	Phosphotransferase enzyme family
COCFMAFH_00675	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COCFMAFH_00676	6.06e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_00677	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
COCFMAFH_00678	8.25e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
COCFMAFH_00679	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
COCFMAFH_00680	5.14e-70	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
COCFMAFH_00681	9.42e-57	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
COCFMAFH_00682	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
COCFMAFH_00683	1.39e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
COCFMAFH_00684	3.7e-297	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COCFMAFH_00685	2.56e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
COCFMAFH_00686	1.97e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
COCFMAFH_00687	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
COCFMAFH_00688	8.5e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COCFMAFH_00689	1.34e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
COCFMAFH_00690	1.9e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
COCFMAFH_00691	5.55e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
COCFMAFH_00692	1.21e-48	-	-	-	-	-	-	-	-
COCFMAFH_00693	5.06e-68	-	-	-	-	-	-	-	-
COCFMAFH_00694	2.24e-261	-	-	-	-	-	-	-	-
COCFMAFH_00695	4.74e-107	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COCFMAFH_00696	9.74e-176	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
COCFMAFH_00697	7.23e-202	yvgN	-	-	S	-	-	-	Aldo keto reductase
COCFMAFH_00698	8.74e-161	XK27_10500	-	-	K	-	-	-	response regulator
COCFMAFH_00699	5.89e-231	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
COCFMAFH_00700	3.52e-174	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_00701	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
COCFMAFH_00702	1.02e-220	-	-	-	L	-	-	-	PFAM Integrase catalytic region
COCFMAFH_00703	2.84e-201	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
COCFMAFH_00704	3.74e-213	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
COCFMAFH_00705	2.01e-29	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
COCFMAFH_00706	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
COCFMAFH_00707	2.25e-201	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
COCFMAFH_00708	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
COCFMAFH_00709	1.8e-190	-	-	-	O	-	-	-	Band 7 protein
COCFMAFH_00710	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
COCFMAFH_00711	8.31e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
COCFMAFH_00712	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
COCFMAFH_00713	4.38e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
COCFMAFH_00714	1.97e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
COCFMAFH_00715	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
COCFMAFH_00716	2.43e-241	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
COCFMAFH_00717	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
COCFMAFH_00718	5.52e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
COCFMAFH_00719	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COCFMAFH_00720	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
COCFMAFH_00721	1.71e-217	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
COCFMAFH_00722	2.1e-219	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
COCFMAFH_00723	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
COCFMAFH_00724	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
COCFMAFH_00725	1.75e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
COCFMAFH_00726	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
COCFMAFH_00727	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COCFMAFH_00728	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
COCFMAFH_00729	8.01e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
COCFMAFH_00730	3.1e-168	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
COCFMAFH_00731	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
COCFMAFH_00732	4.63e-255	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COCFMAFH_00733	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COCFMAFH_00734	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
COCFMAFH_00735	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COCFMAFH_00736	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COCFMAFH_00737	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COCFMAFH_00738	1.41e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COCFMAFH_00739	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
COCFMAFH_00740	2.14e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COCFMAFH_00741	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
COCFMAFH_00742	1.29e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
COCFMAFH_00743	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
COCFMAFH_00744	3.7e-199	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COCFMAFH_00745	6.09e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
COCFMAFH_00746	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
COCFMAFH_00747	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COCFMAFH_00748	1.87e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
COCFMAFH_00749	6.02e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
COCFMAFH_00750	5.27e-64	-	-	-	-	-	-	-	-
COCFMAFH_00751	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
COCFMAFH_00752	8.04e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
COCFMAFH_00753	1.47e-137	-	-	-	NU	-	-	-	mannosyl-glycoprotein
COCFMAFH_00754	1.8e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
COCFMAFH_00755	6.07e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
COCFMAFH_00756	8.76e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
COCFMAFH_00757	5.87e-65	-	-	-	-	-	-	-	-
COCFMAFH_00758	1.62e-34	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
COCFMAFH_00759	1.97e-131	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
COCFMAFH_00761	2.84e-73	-	-	-	-	-	-	-	-
COCFMAFH_00762	7.94e-150	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
COCFMAFH_00764	3.47e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
COCFMAFH_00765	1.92e-153	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
COCFMAFH_00766	1.46e-261	-	-	-	S	-	-	-	associated with various cellular activities
COCFMAFH_00767	1.32e-307	-	-	-	S	-	-	-	Putative metallopeptidase domain
COCFMAFH_00768	4.95e-63	-	-	-	-	-	-	-	-
COCFMAFH_00769	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
COCFMAFH_00770	2.13e-142	-	-	-	K	-	-	-	Helix-turn-helix domain
COCFMAFH_00771	2.18e-115	ymdB	-	-	S	-	-	-	Macro domain protein
COCFMAFH_00772	7.33e-253	-	-	-	EGP	-	-	-	Major Facilitator
COCFMAFH_00773	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COCFMAFH_00774	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
COCFMAFH_00775	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COCFMAFH_00776	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
COCFMAFH_00777	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COCFMAFH_00778	1.01e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
COCFMAFH_00779	3.43e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
COCFMAFH_00780	2.2e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
COCFMAFH_00781	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
COCFMAFH_00782	6.71e-92	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COCFMAFH_00783	4.61e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
COCFMAFH_00784	9.15e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
COCFMAFH_00785	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
COCFMAFH_00786	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
COCFMAFH_00787	1.2e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
COCFMAFH_00788	7.49e-124	-	-	-	-	-	-	-	-
COCFMAFH_00789	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
COCFMAFH_00790	2.07e-202	gspA	-	-	M	-	-	-	family 8
COCFMAFH_00791	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
COCFMAFH_00792	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COCFMAFH_00793	4.09e-306	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
COCFMAFH_00794	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
COCFMAFH_00795	2.99e-218	yvgN	-	-	C	-	-	-	Aldo keto reductase
COCFMAFH_00796	6e-159	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
COCFMAFH_00797	2.91e-109	-	-	-	C	-	-	-	Flavodoxin
COCFMAFH_00798	6.14e-104	-	-	-	S	-	-	-	Cupin domain
COCFMAFH_00799	9.49e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
COCFMAFH_00800	2.9e-309	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
COCFMAFH_00801	2.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
COCFMAFH_00802	5.51e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
COCFMAFH_00803	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
COCFMAFH_00804	1.43e-185	-	-	-	S	-	-	-	DUF218 domain
COCFMAFH_00805	1.38e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COCFMAFH_00806	1.3e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COCFMAFH_00807	6.28e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COCFMAFH_00808	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
COCFMAFH_00809	2.04e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
COCFMAFH_00810	6.05e-290	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
COCFMAFH_00811	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COCFMAFH_00813	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
COCFMAFH_00814	1.4e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
COCFMAFH_00815	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COCFMAFH_00816	7.96e-97	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
COCFMAFH_00817	3.25e-18	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
COCFMAFH_00819	4.65e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COCFMAFH_00820	1.98e-118	-	-	-	-	-	-	-	-
COCFMAFH_00821	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COCFMAFH_00822	3.7e-233	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COCFMAFH_00823	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
COCFMAFH_00824	7.6e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
COCFMAFH_00825	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
COCFMAFH_00826	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
COCFMAFH_00827	2.1e-214	-	-	-	C	-	-	-	Aldo keto reductase
COCFMAFH_00828	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
COCFMAFH_00829	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
COCFMAFH_00830	1.41e-265	-	-	-	P	-	-	-	Voltage gated chloride channel
COCFMAFH_00831	1.13e-289	sptS	-	-	T	-	-	-	Histidine kinase
COCFMAFH_00832	3.15e-153	dltr	-	-	K	-	-	-	response regulator
COCFMAFH_00833	1.76e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
COCFMAFH_00834	1.76e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
COCFMAFH_00835	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
COCFMAFH_00836	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
COCFMAFH_00839	1.35e-202	-	-	-	J	-	-	-	Methyltransferase
COCFMAFH_00840	2.1e-288	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
COCFMAFH_00841	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
COCFMAFH_00843	2.01e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
COCFMAFH_00844	5.62e-224	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
COCFMAFH_00845	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COCFMAFH_00846	1.77e-202	-	-	-	EG	-	-	-	EamA-like transporter family
COCFMAFH_00847	1.26e-44	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
COCFMAFH_00848	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
COCFMAFH_00849	9.4e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
COCFMAFH_00850	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
COCFMAFH_00851	1.27e-291	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COCFMAFH_00852	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
COCFMAFH_00853	6.08e-13	-	-	-	S	-	-	-	CsbD-like
COCFMAFH_00854	3.17e-233	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COCFMAFH_00855	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
COCFMAFH_00856	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
COCFMAFH_00857	8.65e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
COCFMAFH_00858	4.65e-193	-	-	-	-	-	-	-	-
COCFMAFH_00859	6.02e-34	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
COCFMAFH_00860	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
COCFMAFH_00861	2.75e-132	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
COCFMAFH_00862	3.59e-97	-	-	-	F	-	-	-	Nudix hydrolase
COCFMAFH_00863	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
COCFMAFH_00864	1.77e-298	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
COCFMAFH_00865	1.97e-293	-	-	-	-	-	-	-	-
COCFMAFH_00866	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COCFMAFH_00867	4.43e-183	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COCFMAFH_00868	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COCFMAFH_00869	2.07e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COCFMAFH_00870	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COCFMAFH_00871	8.65e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
COCFMAFH_00872	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
COCFMAFH_00873	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
COCFMAFH_00874	0.0	yagE	-	-	E	-	-	-	amino acid
COCFMAFH_00875	9.45e-152	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
COCFMAFH_00876	1.86e-62	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
COCFMAFH_00877	6.85e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
COCFMAFH_00878	9.54e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
COCFMAFH_00884	2.23e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
COCFMAFH_00885	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
COCFMAFH_00887	2.79e-153	-	-	-	I	-	-	-	phosphatase
COCFMAFH_00888	5.02e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
COCFMAFH_00889	2.09e-166	-	-	-	S	-	-	-	Putative threonine/serine exporter
COCFMAFH_00890	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
COCFMAFH_00891	9.44e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
COCFMAFH_00892	2.85e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
COCFMAFH_00893	7.33e-152	-	-	-	S	-	-	-	membrane
COCFMAFH_00894	2.34e-142	-	-	-	S	-	-	-	VIT family
COCFMAFH_00895	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
COCFMAFH_00896	1.14e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_00897	3.85e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COCFMAFH_00898	1.06e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COCFMAFH_00899	2.11e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COCFMAFH_00900	2.9e-275	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
COCFMAFH_00901	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COCFMAFH_00902	9.15e-72	-	-	-	-	-	-	-	-
COCFMAFH_00903	1.26e-96	-	-	-	K	-	-	-	MerR HTH family regulatory protein
COCFMAFH_00904	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
COCFMAFH_00905	1.91e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
COCFMAFH_00906	2.24e-205	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
COCFMAFH_00908	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COCFMAFH_00909	5.59e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
COCFMAFH_00910	1.93e-241	-	-	-	I	-	-	-	Alpha beta
COCFMAFH_00911	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
COCFMAFH_00912	2.22e-151	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
COCFMAFH_00913	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
COCFMAFH_00914	7.21e-205	-	-	-	K	-	-	-	LysR family
COCFMAFH_00915	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
COCFMAFH_00916	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
COCFMAFH_00917	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COCFMAFH_00918	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
COCFMAFH_00919	5.46e-207	mleR	-	-	K	-	-	-	LysR family
COCFMAFH_00920	2.87e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COCFMAFH_00921	1.11e-262	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
COCFMAFH_00922	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
COCFMAFH_00923	2.47e-212	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
COCFMAFH_00924	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
COCFMAFH_00925	1.36e-35	-	-	-	-	-	-	-	-
COCFMAFH_00926	3.67e-255	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
COCFMAFH_00927	5.36e-97	-	-	-	-	-	-	-	-
COCFMAFH_00928	9.29e-290	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COCFMAFH_00929	1.06e-107	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
COCFMAFH_00930	9.19e-287	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
COCFMAFH_00931	1.11e-101	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COCFMAFH_00932	7.07e-144	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
COCFMAFH_00933	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
COCFMAFH_00934	3.07e-265	-	-	-	G	-	-	-	Transporter, major facilitator family protein
COCFMAFH_00935	2.37e-140	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
COCFMAFH_00936	9.54e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
COCFMAFH_00937	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
COCFMAFH_00938	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
COCFMAFH_00939	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
COCFMAFH_00940	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
COCFMAFH_00941	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
COCFMAFH_00942	1.59e-303	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
COCFMAFH_00943	2.23e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COCFMAFH_00944	9.11e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
COCFMAFH_00945	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
COCFMAFH_00946	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
COCFMAFH_00947	5.72e-207	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
COCFMAFH_00948	3.8e-143	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
COCFMAFH_00949	3.11e-211	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COCFMAFH_00950	6.83e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COCFMAFH_00951	2.49e-43	-	-	-	-	-	-	-	-
COCFMAFH_00952	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
COCFMAFH_00954	1.12e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
COCFMAFH_00955	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COCFMAFH_00956	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COCFMAFH_00957	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
COCFMAFH_00958	1.22e-220	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
COCFMAFH_00959	2.11e-271	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
COCFMAFH_00960	1.18e-179	-	-	-	V	-	-	-	Beta-lactamase enzyme family
COCFMAFH_00961	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
COCFMAFH_00962	6.33e-275	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
COCFMAFH_00963	0.0	arcT	-	-	E	-	-	-	Dipeptidase
COCFMAFH_00964	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
COCFMAFH_00965	2.13e-227	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
COCFMAFH_00966	1.19e-215	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
COCFMAFH_00967	6.14e-173	-	-	-	I	-	-	-	alpha/beta hydrolase fold
COCFMAFH_00968	1.67e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
COCFMAFH_00969	6.72e-87	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
COCFMAFH_00970	9.19e-13	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
COCFMAFH_00971	3.23e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
COCFMAFH_00972	7.72e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
COCFMAFH_00973	5.66e-295	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
COCFMAFH_00974	6.26e-113	-	-	-	Q	-	-	-	Methyltransferase
COCFMAFH_00975	3.26e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
COCFMAFH_00976	2.26e-303	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
COCFMAFH_00977	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
COCFMAFH_00978	1.73e-225	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
COCFMAFH_00979	4.82e-180	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COCFMAFH_00980	4.18e-165	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COCFMAFH_00981	7.28e-101	-	-	-	S	-	-	-	Flavodoxin
COCFMAFH_00982	3.25e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
COCFMAFH_00983	4.04e-48	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
COCFMAFH_00984	5.25e-279	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
COCFMAFH_00985	4.74e-213	-	-	-	H	-	-	-	geranyltranstransferase activity
COCFMAFH_00986	9.46e-235	-	-	-	-	-	-	-	-
COCFMAFH_00987	8.9e-26	-	-	-	-	-	-	-	-
COCFMAFH_00988	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
COCFMAFH_00989	3.74e-242	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
COCFMAFH_00990	1.56e-60	-	-	-	-	-	-	-	-
COCFMAFH_00991	2.03e-136	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
COCFMAFH_00992	9.66e-110	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
COCFMAFH_00993	2.19e-291	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
COCFMAFH_00994	1.65e-107	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
COCFMAFH_00995	1.35e-238	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
COCFMAFH_00996	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COCFMAFH_00997	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
COCFMAFH_00998	4.54e-125	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
COCFMAFH_00999	7.16e-163	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
COCFMAFH_01000	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
COCFMAFH_01001	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COCFMAFH_01002	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COCFMAFH_01003	1.51e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COCFMAFH_01004	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COCFMAFH_01005	1.25e-241	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COCFMAFH_01006	7.54e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
COCFMAFH_01007	6.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
COCFMAFH_01008	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COCFMAFH_01009	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COCFMAFH_01010	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
COCFMAFH_01011	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COCFMAFH_01012	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
COCFMAFH_01013	2.4e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
COCFMAFH_01014	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COCFMAFH_01015	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
COCFMAFH_01016	7.62e-258	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
COCFMAFH_01017	6.11e-158	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
COCFMAFH_01018	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
COCFMAFH_01019	1.43e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
COCFMAFH_01020	5.35e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
COCFMAFH_01021	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
COCFMAFH_01022	7.17e-146	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
COCFMAFH_01023	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
COCFMAFH_01024	7.6e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
COCFMAFH_01025	7.97e-292	-	-	-	-	-	-	-	-
COCFMAFH_01026	2.59e-34	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
COCFMAFH_01027	9.01e-57	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
COCFMAFH_01028	2.74e-139	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
COCFMAFH_01029	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
COCFMAFH_01030	7.48e-155	-	-	-	GM	-	-	-	NmrA-like family
COCFMAFH_01031	5.36e-92	-	-	-	S	ko:K02348	-	ko00000	Gnat family
COCFMAFH_01032	3.66e-45	-	-	-	S	-	-	-	Cytochrome B5
COCFMAFH_01033	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
COCFMAFH_01034	4.51e-54	-	-	-	S	-	-	-	Cytochrome B5
COCFMAFH_01035	1.37e-269	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
COCFMAFH_01037	1.63e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COCFMAFH_01038	1.77e-168	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
COCFMAFH_01039	4.62e-21	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
COCFMAFH_01040	8.94e-250	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
COCFMAFH_01041	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
COCFMAFH_01042	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COCFMAFH_01043	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COCFMAFH_01044	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COCFMAFH_01045	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COCFMAFH_01046	1.15e-263	-	-	-	-	-	-	-	-
COCFMAFH_01047	1.97e-153	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
COCFMAFH_01048	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COCFMAFH_01049	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COCFMAFH_01050	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COCFMAFH_01051	2.7e-112	-	-	-	L	-	-	-	Transposase
COCFMAFH_01052	5.17e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
COCFMAFH_01053	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COCFMAFH_01054	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
COCFMAFH_01055	8.18e-174	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
COCFMAFH_01056	4.16e-180	-	-	-	S	-	-	-	Membrane
COCFMAFH_01057	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
COCFMAFH_01058	9.79e-29	-	-	-	-	-	-	-	-
COCFMAFH_01059	2.03e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
COCFMAFH_01060	1.88e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
COCFMAFH_01061	3.61e-61	-	-	-	-	-	-	-	-
COCFMAFH_01062	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
COCFMAFH_01063	8.8e-264	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
COCFMAFH_01064	2.95e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
COCFMAFH_01065	3.47e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
COCFMAFH_01066	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
COCFMAFH_01067	2.23e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
COCFMAFH_01068	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
COCFMAFH_01069	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
COCFMAFH_01070	1.23e-177	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
COCFMAFH_01071	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
COCFMAFH_01072	3.91e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COCFMAFH_01073	5.15e-269	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COCFMAFH_01074	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
COCFMAFH_01075	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COCFMAFH_01076	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
COCFMAFH_01077	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COCFMAFH_01078	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COCFMAFH_01079	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COCFMAFH_01080	5.06e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
COCFMAFH_01081	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COCFMAFH_01082	3.25e-60	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
COCFMAFH_01083	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
COCFMAFH_01084	5.98e-14	-	-	-	-	-	-	-	-
COCFMAFH_01085	8.81e-89	-	-	-	K	-	-	-	Transcriptional regulator
COCFMAFH_01086	4.03e-299	-	-	-	EGP	-	-	-	Major Facilitator
COCFMAFH_01087	6.65e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
COCFMAFH_01088	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
COCFMAFH_01089	1.73e-148	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
COCFMAFH_01090	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COCFMAFH_01091	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COCFMAFH_01092	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COCFMAFH_01093	2.11e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
COCFMAFH_01094	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
COCFMAFH_01095	2.79e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COCFMAFH_01096	3.31e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COCFMAFH_01097	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
COCFMAFH_01098	8.87e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
COCFMAFH_01099	5.04e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
COCFMAFH_01100	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
COCFMAFH_01101	1.43e-208	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
COCFMAFH_01102	9.67e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COCFMAFH_01103	8.31e-187	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
COCFMAFH_01104	1.55e-109	-	-	-	-	-	-	-	-
COCFMAFH_01105	8.83e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
COCFMAFH_01106	9e-72	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
COCFMAFH_01107	3.67e-46	-	-	-	-	-	-	-	-
COCFMAFH_01108	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COCFMAFH_01109	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
COCFMAFH_01110	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
COCFMAFH_01111	7.57e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COCFMAFH_01112	1.78e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
COCFMAFH_01113	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
COCFMAFH_01114	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COCFMAFH_01115	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COCFMAFH_01116	4.04e-284	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COCFMAFH_01117	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
COCFMAFH_01118	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COCFMAFH_01119	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COCFMAFH_01120	4.72e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COCFMAFH_01121	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COCFMAFH_01122	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
COCFMAFH_01123	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
COCFMAFH_01124	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
COCFMAFH_01125	1.91e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
COCFMAFH_01126	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
COCFMAFH_01127	8.84e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COCFMAFH_01128	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
COCFMAFH_01129	4.26e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
COCFMAFH_01130	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COCFMAFH_01131	8.26e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COCFMAFH_01132	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COCFMAFH_01133	4.44e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COCFMAFH_01134	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COCFMAFH_01135	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
COCFMAFH_01136	9e-72	-	-	-	-	-	-	-	-
COCFMAFH_01137	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
COCFMAFH_01138	3.2e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
COCFMAFH_01139	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
COCFMAFH_01140	6.95e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
COCFMAFH_01141	4.02e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COCFMAFH_01142	1.09e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COCFMAFH_01143	6.56e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COCFMAFH_01144	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COCFMAFH_01145	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
COCFMAFH_01146	1.22e-147	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
COCFMAFH_01147	4.3e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
COCFMAFH_01148	3.84e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COCFMAFH_01149	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
COCFMAFH_01150	1.77e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
COCFMAFH_01151	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
COCFMAFH_01152	1.34e-144	-	-	-	K	-	-	-	Transcriptional regulator
COCFMAFH_01156	4.21e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
COCFMAFH_01157	1.47e-223	-	-	-	-	-	-	-	-
COCFMAFH_01158	4.87e-203	-	-	-	-	-	-	-	-
COCFMAFH_01159	1.54e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
COCFMAFH_01160	1.99e-131	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COCFMAFH_01161	3.42e-197	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
COCFMAFH_01162	1.28e-18	-	-	-	-	-	-	-	-
COCFMAFH_01163	8.16e-226	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COCFMAFH_01164	3.64e-24	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COCFMAFH_01165	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COCFMAFH_01166	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
COCFMAFH_01167	1.01e-226	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COCFMAFH_01168	2.39e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
COCFMAFH_01169	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
COCFMAFH_01170	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
COCFMAFH_01171	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
COCFMAFH_01172	7.32e-35	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
COCFMAFH_01173	1.43e-16	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
COCFMAFH_01174	9.34e-130	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COCFMAFH_01175	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
COCFMAFH_01176	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
COCFMAFH_01177	0.0	-	-	-	S	-	-	-	membrane
COCFMAFH_01178	1.33e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
COCFMAFH_01179	8.69e-45	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
COCFMAFH_01180	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
COCFMAFH_01181	5.72e-224	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
COCFMAFH_01182	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
COCFMAFH_01183	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
COCFMAFH_01184	5.11e-188	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COCFMAFH_01185	1.1e-157	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
COCFMAFH_01188	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COCFMAFH_01189	9.61e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
COCFMAFH_01190	2.57e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
COCFMAFH_01191	2.6e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
COCFMAFH_01192	9.02e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
COCFMAFH_01193	8.59e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
COCFMAFH_01194	5.68e-279	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
COCFMAFH_01195	9.17e-59	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
COCFMAFH_01196	8.11e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COCFMAFH_01197	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
COCFMAFH_01198	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COCFMAFH_01200	3.16e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COCFMAFH_01201	0.0	-	-	-	L	-	-	-	DNA helicase
COCFMAFH_01202	4.08e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
COCFMAFH_01203	1.2e-240	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
COCFMAFH_01204	5.54e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
COCFMAFH_01205	2.47e-230	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
COCFMAFH_01206	4.52e-80	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
COCFMAFH_01207	1.27e-40	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
COCFMAFH_01208	1.2e-131	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
COCFMAFH_01209	2.85e-114	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
COCFMAFH_01210	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COCFMAFH_01211	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
COCFMAFH_01212	4.16e-19	-	-	-	-	-	-	-	-
COCFMAFH_01213	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COCFMAFH_01214	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COCFMAFH_01215	5.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
COCFMAFH_01216	8.05e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
COCFMAFH_01217	2.33e-238	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
COCFMAFH_01218	1.94e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
COCFMAFH_01220	1.83e-21	-	-	-	-	-	-	-	-
COCFMAFH_01221	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COCFMAFH_01223	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COCFMAFH_01224	1.08e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
COCFMAFH_01225	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COCFMAFH_01226	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COCFMAFH_01227	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
COCFMAFH_01228	1.4e-34	-	-	-	K	-	-	-	TRANSCRIPTIONal
COCFMAFH_01229	7.69e-07	-	-	-	K	-	-	-	TRANSCRIPTIONal
COCFMAFH_01230	2.55e-167	-	-	-	L	-	-	-	PFAM Integrase catalytic region
COCFMAFH_01231	1.03e-167	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
COCFMAFH_01232	1.42e-88	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COCFMAFH_01233	3.59e-26	-	-	-	-	-	-	-	-
COCFMAFH_01234	6.62e-66	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
COCFMAFH_01235	1.41e-67	-	-	-	-	-	-	-	-
COCFMAFH_01237	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
COCFMAFH_01238	1.23e-96	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
COCFMAFH_01239	7.04e-48	-	-	-	K	-	-	-	Transcriptional regulator
COCFMAFH_01240	5.32e-102	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
COCFMAFH_01241	5.9e-99	arbY	-	-	M	-	-	-	family 8
COCFMAFH_01242	2.14e-98	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
COCFMAFH_01243	2.38e-68	arbV	-	-	I	-	-	-	Phosphate acyltransferases
COCFMAFH_01244	3.91e-215	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COCFMAFH_01245	2.15e-75	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
COCFMAFH_01246	3.39e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
COCFMAFH_01247	1.1e-211	-	-	-	S	-	-	-	Protein of unknown function DUF262
COCFMAFH_01248	1.34e-123	-	-	-	L	-	-	-	Integrase
COCFMAFH_01249	1.23e-311	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
COCFMAFH_01250	1.43e-291	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
COCFMAFH_01251	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
COCFMAFH_01252	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
COCFMAFH_01253	6.92e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
COCFMAFH_01254	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
COCFMAFH_01255	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COCFMAFH_01256	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COCFMAFH_01257	2.48e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
COCFMAFH_01258	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COCFMAFH_01259	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COCFMAFH_01260	1.47e-99	-	-	-	K	-	-	-	Transcriptional regulator
COCFMAFH_01261	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
COCFMAFH_01262	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
COCFMAFH_01263	1.39e-83	-	-	-	GM	-	-	-	NAD(P)H-binding
COCFMAFH_01264	1.02e-120	-	-	-	K	-	-	-	Virulence activator alpha C-term
COCFMAFH_01265	1.69e-118	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
COCFMAFH_01266	2.05e-195	-	-	-	S	-	-	-	Alpha beta hydrolase
COCFMAFH_01267	8.09e-44	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
COCFMAFH_01268	7.41e-114	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
COCFMAFH_01269	2.15e-203	lysR	-	-	K	-	-	-	Transcriptional regulator
COCFMAFH_01270	2.67e-111	-	-	-	C	-	-	-	Flavodoxin
COCFMAFH_01271	1.12e-210	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
COCFMAFH_01272	1.34e-209	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
COCFMAFH_01273	4.09e-99	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COCFMAFH_01274	1.2e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COCFMAFH_01275	1.16e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
COCFMAFH_01276	4.47e-12	-	-	-	P	-	-	-	FAD-binding domain
COCFMAFH_01277	1.2e-25	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
COCFMAFH_01278	2.28e-139	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
COCFMAFH_01279	1.66e-303	-	-	-	T	-	-	-	GHKL domain
COCFMAFH_01280	1.18e-155	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
COCFMAFH_01281	6.74e-35	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
COCFMAFH_01282	4.22e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
COCFMAFH_01283	1.01e-28	-	-	-	-	-	-	-	-
COCFMAFH_01284	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
COCFMAFH_01285	4.68e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
COCFMAFH_01286	2.54e-60	yrvD	-	-	S	-	-	-	Pfam:DUF1049
COCFMAFH_01288	1.47e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
COCFMAFH_01289	2.6e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COCFMAFH_01290	7.05e-101	-	-	-	I	-	-	-	alpha/beta hydrolase fold
COCFMAFH_01291	3.55e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
COCFMAFH_01292	1.72e-65	-	-	-	-	-	-	-	-
COCFMAFH_01293	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COCFMAFH_01294	1.54e-52	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
COCFMAFH_01295	1.32e-266	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
COCFMAFH_01296	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
COCFMAFH_01297	0.0	-	-	-	M	-	-	-	domain protein
COCFMAFH_01298	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
COCFMAFH_01299	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
COCFMAFH_01300	8.53e-95	-	-	-	-	-	-	-	-
COCFMAFH_01302	3.77e-245	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
COCFMAFH_01303	3.88e-188	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
COCFMAFH_01304	3.45e-246	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
COCFMAFH_01305	4.53e-272	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
COCFMAFH_01306	5.21e-198	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
COCFMAFH_01307	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COCFMAFH_01308	3.86e-284	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
COCFMAFH_01309	1.21e-247	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
COCFMAFH_01314	6.59e-48	-	-	-	-	-	-	-	-
COCFMAFH_01315	4.08e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
COCFMAFH_01316	2.08e-39	-	-	-	-	-	-	-	-
COCFMAFH_01317	1.41e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
COCFMAFH_01318	1.08e-293	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
COCFMAFH_01319	4.5e-47	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
COCFMAFH_01320	1.59e-49	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
COCFMAFH_01322	0.0	snf	-	-	KL	-	-	-	domain protein
COCFMAFH_01323	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
COCFMAFH_01324	1.25e-224	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
COCFMAFH_01325	9.18e-265	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
COCFMAFH_01326	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
COCFMAFH_01327	7.21e-35	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
COCFMAFH_01328	1.18e-50	-	-	-	-	-	-	-	-
COCFMAFH_01329	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_01330	4.22e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_01331	5.92e-226	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
COCFMAFH_01332	2.72e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
COCFMAFH_01333	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
COCFMAFH_01334	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
COCFMAFH_01335	2.52e-78	-	-	-	-	-	-	-	-
COCFMAFH_01336	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COCFMAFH_01338	8.57e-289	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
COCFMAFH_01339	5.32e-272	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
COCFMAFH_01340	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
COCFMAFH_01341	4.95e-195	-	-	-	E	-	-	-	AzlC protein
COCFMAFH_01342	5.47e-261	hpk31	-	-	T	-	-	-	Histidine kinase
COCFMAFH_01343	3.27e-159	vanR	-	-	K	-	-	-	response regulator
COCFMAFH_01344	5.72e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COCFMAFH_01345	1.32e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
COCFMAFH_01346	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
COCFMAFH_01347	8.75e-298	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
COCFMAFH_01348	1.09e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
COCFMAFH_01349	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
COCFMAFH_01350	4.25e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
COCFMAFH_01351	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COCFMAFH_01352	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
COCFMAFH_01353	4.83e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
COCFMAFH_01354	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
COCFMAFH_01355	3.73e-200	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
COCFMAFH_01356	6.29e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
COCFMAFH_01357	5.97e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
COCFMAFH_01358	2.76e-217	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
COCFMAFH_01359	1.14e-276	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
COCFMAFH_01360	1.77e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
COCFMAFH_01362	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_01363	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COCFMAFH_01364	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COCFMAFH_01365	1.35e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
COCFMAFH_01366	1.74e-94	-	-	-	L	-	-	-	Helix-turn-helix domain
COCFMAFH_01367	8.31e-06	-	-	-	L	-	-	-	Helix-turn-helix domain
COCFMAFH_01368	8.58e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COCFMAFH_01369	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COCFMAFH_01370	3.82e-157	-	-	-	S	-	-	-	repeat protein
COCFMAFH_01371	6.67e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
COCFMAFH_01372	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COCFMAFH_01373	1.13e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
COCFMAFH_01374	1.75e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
COCFMAFH_01375	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COCFMAFH_01376	1.54e-33	-	-	-	-	-	-	-	-
COCFMAFH_01377	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
COCFMAFH_01378	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
COCFMAFH_01379	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COCFMAFH_01380	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
COCFMAFH_01381	1.97e-185	ylmH	-	-	S	-	-	-	S4 domain protein
COCFMAFH_01382	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
COCFMAFH_01383	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COCFMAFH_01384	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COCFMAFH_01385	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COCFMAFH_01386	8.69e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COCFMAFH_01387	1.45e-260	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COCFMAFH_01388	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COCFMAFH_01389	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COCFMAFH_01390	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
COCFMAFH_01391	3.47e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
COCFMAFH_01392	9.31e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COCFMAFH_01393	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
COCFMAFH_01394	7.76e-74	-	-	-	-	-	-	-	-
COCFMAFH_01395	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
COCFMAFH_01396	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
COCFMAFH_01397	1.53e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COCFMAFH_01398	8.5e-208	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
COCFMAFH_01399	6.56e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
COCFMAFH_01401	3.81e-88	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
COCFMAFH_01402	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
COCFMAFH_01403	0.0	cadA	-	-	P	-	-	-	P-type ATPase
COCFMAFH_01404	5.23e-276	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
COCFMAFH_01405	4.44e-11	-	-	-	-	-	-	-	-
COCFMAFH_01406	2.14e-196	-	-	-	GM	-	-	-	NAD(P)H-binding
COCFMAFH_01407	1.29e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
COCFMAFH_01408	1.77e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
COCFMAFH_01409	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COCFMAFH_01410	1.01e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_01411	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
COCFMAFH_01412	3.53e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
COCFMAFH_01413	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
COCFMAFH_01414	1.96e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
COCFMAFH_01415	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COCFMAFH_01416	4.92e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COCFMAFH_01417	2.06e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
COCFMAFH_01418	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
COCFMAFH_01419	1.56e-152	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COCFMAFH_01420	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
COCFMAFH_01421	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COCFMAFH_01422	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COCFMAFH_01423	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COCFMAFH_01424	8.8e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COCFMAFH_01425	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COCFMAFH_01426	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COCFMAFH_01427	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
COCFMAFH_01428	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COCFMAFH_01429	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COCFMAFH_01430	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COCFMAFH_01431	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COCFMAFH_01432	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COCFMAFH_01433	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COCFMAFH_01434	1.06e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COCFMAFH_01435	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COCFMAFH_01436	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COCFMAFH_01437	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
COCFMAFH_01438	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
COCFMAFH_01439	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COCFMAFH_01440	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COCFMAFH_01441	9.82e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COCFMAFH_01442	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
COCFMAFH_01443	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COCFMAFH_01444	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COCFMAFH_01445	8.91e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COCFMAFH_01446	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
COCFMAFH_01451	2.76e-43	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
COCFMAFH_01453	1.14e-21	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
COCFMAFH_01454	3.61e-169	yocS	-	-	S	ko:K03453	-	ko00000	Transporter
COCFMAFH_01455	1.72e-36	XK27_02560	-	-	S	-	-	-	Pfam:DUF59
COCFMAFH_01456	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
COCFMAFH_01457	6.8e-136	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COCFMAFH_01458	0.0	ilvD	4.2.1.9	-	EG	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
COCFMAFH_01459	3.45e-52	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
COCFMAFH_01460	6.86e-200	yocS	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
COCFMAFH_01461	4.3e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
COCFMAFH_01462	8.05e-264	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
COCFMAFH_01463	3.02e-95	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
COCFMAFH_01464	9.83e-107	-	-	-	-	-	-	-	-
COCFMAFH_01465	6.82e-38	-	-	-	M	-	-	-	biosynthesis protein
COCFMAFH_01466	3.87e-96	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
COCFMAFH_01467	1.46e-82	-	-	-	S	-	-	-	Glycosyltransferase like family
COCFMAFH_01468	5.35e-100	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
COCFMAFH_01469	6.67e-89	-	-	-	S	-	-	-	Acyltransferase family
COCFMAFH_01471	6.37e-90	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COCFMAFH_01472	1.19e-210	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
COCFMAFH_01473	1.27e-23	-	-	-	S	-	-	-	integral membrane protein
COCFMAFH_01474	4.84e-07	-	-	-	S	-	-	-	integral membrane protein
COCFMAFH_01475	1.72e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
COCFMAFH_01476	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
COCFMAFH_01477	3.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COCFMAFH_01478	3.05e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
COCFMAFH_01479	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
COCFMAFH_01480	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
COCFMAFH_01481	8.8e-17	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
COCFMAFH_01482	8.25e-61	pgdA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
COCFMAFH_01483	0.0	-	-	-	G	-	-	-	Right handed beta helix region
COCFMAFH_01484	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
COCFMAFH_01486	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
COCFMAFH_01487	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
COCFMAFH_01489	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
COCFMAFH_01490	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
COCFMAFH_01491	2.41e-315	yycH	-	-	S	-	-	-	YycH protein
COCFMAFH_01492	4.13e-192	yycI	-	-	S	-	-	-	YycH protein
COCFMAFH_01493	5.93e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
COCFMAFH_01494	1.84e-282	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
COCFMAFH_01495	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
COCFMAFH_01496	1.81e-226	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
COCFMAFH_01497	7.54e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COCFMAFH_01499	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
COCFMAFH_01500	3.8e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COCFMAFH_01501	1.09e-250	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
COCFMAFH_01502	1.73e-288	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
COCFMAFH_01503	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COCFMAFH_01504	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
COCFMAFH_01505	1.38e-37	-	-	-	-	-	-	-	-
COCFMAFH_01506	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
COCFMAFH_01507	7.43e-129	-	-	-	S	-	-	-	Pfam:DUF3816
COCFMAFH_01508	2.24e-181	-	-	-	G	-	-	-	MucBP domain
COCFMAFH_01509	2.26e-145	-	-	-	-	-	-	-	-
COCFMAFH_01510	6.4e-202	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_01511	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
COCFMAFH_01512	1.85e-127	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
COCFMAFH_01513	3.43e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
COCFMAFH_01514	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
COCFMAFH_01515	3.34e-215	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
COCFMAFH_01516	1.38e-59	-	-	-	-	-	-	-	-
COCFMAFH_01517	9.73e-132	-	-	-	L	-	-	-	Integrase
COCFMAFH_01518	1.5e-80	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
COCFMAFH_01519	4.41e-52	-	-	-	K	-	-	-	Helix-turn-helix domain
COCFMAFH_01528	9.45e-06	-	-	-	-	-	-	-	-
COCFMAFH_01529	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COCFMAFH_01530	9.53e-207	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COCFMAFH_01531	5.58e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
COCFMAFH_01532	1.44e-257	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COCFMAFH_01533	2.83e-236	arbY	-	-	M	-	-	-	family 8
COCFMAFH_01534	1.1e-233	-	-	-	M	-	-	-	Glycosyltransferase like family 2
COCFMAFH_01535	5.91e-234	-	-	-	M	-	-	-	Glycosyl transferase, family 2
COCFMAFH_01536	3.69e-296	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COCFMAFH_01537	3.19e-302	-	-	-	S	-	-	-	polysaccharide biosynthetic process
COCFMAFH_01538	4.61e-274	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
COCFMAFH_01539	7.89e-168	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
COCFMAFH_01540	3.12e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
COCFMAFH_01541	2.41e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COCFMAFH_01542	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
COCFMAFH_01543	4.61e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COCFMAFH_01544	6.2e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COCFMAFH_01545	3.47e-286	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COCFMAFH_01546	3e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
COCFMAFH_01547	3.95e-203	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
COCFMAFH_01548	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COCFMAFH_01549	1.33e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COCFMAFH_01550	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
COCFMAFH_01551	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COCFMAFH_01553	3.82e-255	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COCFMAFH_01554	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
COCFMAFH_01555	2.41e-111	-	-	-	F	-	-	-	NUDIX domain
COCFMAFH_01556	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COCFMAFH_01557	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COCFMAFH_01558	1.1e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COCFMAFH_01559	7.89e-212	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
COCFMAFH_01560	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COCFMAFH_01561	1.3e-205	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
COCFMAFH_01562	2.05e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COCFMAFH_01563	1.99e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COCFMAFH_01564	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
COCFMAFH_01565	4.05e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
COCFMAFH_01566	4.79e-221	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
COCFMAFH_01567	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
COCFMAFH_01568	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
COCFMAFH_01569	3.38e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COCFMAFH_01570	3.61e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COCFMAFH_01571	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_01572	2.01e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COCFMAFH_01573	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
COCFMAFH_01574	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COCFMAFH_01575	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
COCFMAFH_01576	1e-272	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
COCFMAFH_01577	3.8e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
COCFMAFH_01578	3.15e-54	-	-	-	M	-	-	-	Lysin motif
COCFMAFH_01579	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
COCFMAFH_01580	7.6e-246	-	-	-	S	-	-	-	Helix-turn-helix domain
COCFMAFH_01581	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COCFMAFH_01582	1.67e-163	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
COCFMAFH_01583	1.35e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COCFMAFH_01584	1.95e-177	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COCFMAFH_01585	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COCFMAFH_01586	2.74e-210	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
COCFMAFH_01587	1.08e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
COCFMAFH_01588	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
COCFMAFH_01589	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
COCFMAFH_01590	1.11e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
COCFMAFH_01591	5.28e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
COCFMAFH_01592	1.85e-201	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COCFMAFH_01593	2.2e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
COCFMAFH_01594	1.69e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COCFMAFH_01595	2.09e-265	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COCFMAFH_01596	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COCFMAFH_01597	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
COCFMAFH_01598	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
COCFMAFH_01599	2.14e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
COCFMAFH_01600	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COCFMAFH_01601	1.8e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
COCFMAFH_01602	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COCFMAFH_01603	3.62e-184	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
COCFMAFH_01604	3.06e-27	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
COCFMAFH_01605	4.11e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COCFMAFH_01606	5.1e-121	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
COCFMAFH_01607	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
COCFMAFH_01608	2.36e-171	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
COCFMAFH_01609	5.87e-50	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
COCFMAFH_01610	1.2e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COCFMAFH_01611	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
COCFMAFH_01612	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COCFMAFH_01613	1.05e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COCFMAFH_01614	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
COCFMAFH_01615	2.9e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COCFMAFH_01616	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
COCFMAFH_01617	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COCFMAFH_01618	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COCFMAFH_01619	1.86e-288	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
COCFMAFH_01621	7.39e-311	-	-	-	M	-	-	-	Glycosyl transferase family group 2
COCFMAFH_01622	3.88e-76	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COCFMAFH_01623	3.25e-162	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COCFMAFH_01624	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COCFMAFH_01625	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COCFMAFH_01626	2.91e-65	-	-	-	-	-	-	-	-
COCFMAFH_01628	1.37e-79	-	-	-	M	-	-	-	MucBP domain
COCFMAFH_01630	8.49e-08	-	-	-	K	-	-	-	peptidyl-tyrosine sulfation
COCFMAFH_01635	4.38e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
COCFMAFH_01636	2.08e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
COCFMAFH_01637	1.09e-227	-	-	-	-	-	-	-	-
COCFMAFH_01638	1.02e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
COCFMAFH_01640	4.74e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
COCFMAFH_01641	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COCFMAFH_01642	5.3e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
COCFMAFH_01643	6.03e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COCFMAFH_01644	9.83e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COCFMAFH_01645	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
COCFMAFH_01646	5.5e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COCFMAFH_01647	2.78e-38	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
COCFMAFH_01648	1.57e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COCFMAFH_01649	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
COCFMAFH_01650	1.45e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COCFMAFH_01651	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COCFMAFH_01652	1.64e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COCFMAFH_01653	9.32e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COCFMAFH_01654	1.43e-177	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COCFMAFH_01655	1.62e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COCFMAFH_01656	2.58e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COCFMAFH_01657	6.98e-156	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
COCFMAFH_01658	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
COCFMAFH_01659	4.46e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
COCFMAFH_01660	1.62e-118	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
COCFMAFH_01661	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
COCFMAFH_01662	2.06e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_01663	4.04e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
COCFMAFH_01664	2.13e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
COCFMAFH_01665	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
COCFMAFH_01666	2.06e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
COCFMAFH_01667	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COCFMAFH_01668	3.1e-246	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COCFMAFH_01669	4.47e-229	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
COCFMAFH_01671	0.0	-	-	-	L	-	-	-	PLD-like domain
COCFMAFH_01672	2.93e-117	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
COCFMAFH_01673	1.7e-201	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
COCFMAFH_01674	6.37e-76	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
COCFMAFH_01675	5.87e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COCFMAFH_01676	1.13e-29	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
COCFMAFH_01677	1.11e-196	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COCFMAFH_01678	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
COCFMAFH_01679	4.41e-218	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
COCFMAFH_01680	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
COCFMAFH_01682	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
COCFMAFH_01683	4.3e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
COCFMAFH_01684	2.46e-113	-	-	-	-	-	-	-	-
COCFMAFH_01685	6.55e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
COCFMAFH_01686	1.01e-272	yttB	-	-	EGP	-	-	-	Major Facilitator
COCFMAFH_01687	1.03e-146	-	-	-	-	-	-	-	-
COCFMAFH_01688	2.14e-32	-	-	-	-	-	-	-	-
COCFMAFH_01689	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
COCFMAFH_01690	7.15e-315	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COCFMAFH_01691	1.01e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
COCFMAFH_01692	2.58e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
COCFMAFH_01693	3.33e-133	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COCFMAFH_01694	9.81e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
COCFMAFH_01695	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
COCFMAFH_01696	1.1e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
COCFMAFH_01697	6.23e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
COCFMAFH_01698	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COCFMAFH_01699	1.84e-75	-	-	-	-	-	-	-	-
COCFMAFH_01700	1.08e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
COCFMAFH_01701	1.63e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
COCFMAFH_01702	1.15e-178	-	-	-	-	-	-	-	-
COCFMAFH_01703	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
COCFMAFH_01704	3.3e-265	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
COCFMAFH_01705	4.37e-39	-	-	-	-	-	-	-	-
COCFMAFH_01706	1.69e-229	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
COCFMAFH_01707	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
COCFMAFH_01708	6.08e-102	-	-	-	-	-	-	-	-
COCFMAFH_01709	1.38e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COCFMAFH_01710	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
COCFMAFH_01711	1.1e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
COCFMAFH_01712	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COCFMAFH_01713	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
COCFMAFH_01714	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
COCFMAFH_01715	1.17e-61	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
COCFMAFH_01716	3.86e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
COCFMAFH_01717	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
COCFMAFH_01718	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
COCFMAFH_01719	6.06e-308	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COCFMAFH_01720	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
COCFMAFH_01721	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
COCFMAFH_01722	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COCFMAFH_01723	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COCFMAFH_01724	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COCFMAFH_01725	9.72e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COCFMAFH_01726	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COCFMAFH_01727	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COCFMAFH_01728	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
COCFMAFH_01729	2.3e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
COCFMAFH_01730	4.71e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
COCFMAFH_01731	6.71e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
COCFMAFH_01732	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COCFMAFH_01733	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COCFMAFH_01734	7.62e-290	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COCFMAFH_01735	1.55e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COCFMAFH_01736	1.86e-208	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COCFMAFH_01737	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COCFMAFH_01738	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
COCFMAFH_01739	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
COCFMAFH_01740	4.87e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
COCFMAFH_01741	1.97e-297	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
COCFMAFH_01742	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
COCFMAFH_01743	1.77e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
COCFMAFH_01744	1.25e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
COCFMAFH_01745	9.5e-239	ampC	-	-	V	-	-	-	Beta-lactamase
COCFMAFH_01746	8.92e-73	-	-	-	-	-	-	-	-
COCFMAFH_01747	0.0	-	-	-	M	-	-	-	domain protein
COCFMAFH_01748	9.23e-138	-	-	-	-	-	-	-	-
COCFMAFH_01749	1.67e-146	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COCFMAFH_01750	0.000223	-	-	-	L	-	-	-	GIY-YIG catalytic domain
COCFMAFH_01751	2.01e-09	-	-	-	S	-	-	-	Helix-turn-helix domain
COCFMAFH_01754	3.16e-11	-	-	-	S	-	-	-	Primase C terminal 1 (PriCT-1)
COCFMAFH_01755	7.57e-108	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
COCFMAFH_01759	9.09e-41	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
COCFMAFH_01760	2.99e-32	terS	-	-	L	-	-	-	Phage terminase, small subunit
COCFMAFH_01761	1.3e-248	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
COCFMAFH_01762	1.14e-177	-	-	-	S	-	-	-	Phage portal protein
COCFMAFH_01763	2.35e-239	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
COCFMAFH_01764	2.16e-22	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
COCFMAFH_01768	2.2e-200	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
COCFMAFH_01769	4.95e-92	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
COCFMAFH_01771	2.13e-74	-	-	-	-	-	-	-	-
COCFMAFH_01773	1.23e-110	-	-	-	-	-	-	-	-
COCFMAFH_01774	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
COCFMAFH_01775	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
COCFMAFH_01776	1.6e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
COCFMAFH_01777	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
COCFMAFH_01778	1.29e-205	-	-	-	EG	-	-	-	EamA-like transporter family
COCFMAFH_01779	4.67e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
COCFMAFH_01780	1.87e-145	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
COCFMAFH_01781	4.5e-67	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
COCFMAFH_01782	2.57e-61	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
COCFMAFH_01783	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
COCFMAFH_01784	1.61e-54	-	-	-	-	-	-	-	-
COCFMAFH_01785	4.41e-61	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
COCFMAFH_01787	2.07e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
COCFMAFH_01788	4.18e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COCFMAFH_01789	1.08e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
COCFMAFH_01790	9.28e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
COCFMAFH_01791	2.87e-171	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COCFMAFH_01792	1.03e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
COCFMAFH_01793	1.83e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
COCFMAFH_01794	1.77e-55	-	-	-	-	-	-	-	-
COCFMAFH_01795	1.37e-95	-	-	-	KV	ko:K01990	-	ko00000,ko00002,ko02000	of ABC transporters with duplicated ATPase domains
COCFMAFH_01796	0.0	-	-	-	J	-	-	-	Elongation factor G, domain IV
COCFMAFH_01798	6.38e-122	-	-	-	L	-	-	-	Integrase
COCFMAFH_01799	1.43e-57	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
COCFMAFH_01800	1.28e-65	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
COCFMAFH_01802	1.63e-281	-	-	-	-	-	-	-	-
COCFMAFH_01803	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
COCFMAFH_01804	5.29e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COCFMAFH_01805	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COCFMAFH_01806	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COCFMAFH_01807	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
COCFMAFH_01808	4.82e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
COCFMAFH_01809	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
COCFMAFH_01810	3.14e-188	yidA	-	-	S	-	-	-	hydrolase
COCFMAFH_01811	1.6e-100	-	-	-	-	-	-	-	-
COCFMAFH_01812	1.1e-125	-	-	-	S	-	-	-	reductase
COCFMAFH_01813	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
COCFMAFH_01814	2.41e-189	-	-	-	E	-	-	-	Glyoxalase-like domain
COCFMAFH_01815	3.39e-186	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COCFMAFH_01816	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
COCFMAFH_01817	4.09e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COCFMAFH_01818	4.85e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
COCFMAFH_01819	7.58e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
COCFMAFH_01820	1.99e-38	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
COCFMAFH_01821	2.05e-77	-	-	-	-	-	-	-	-
COCFMAFH_01822	2.36e-299	-	-	-	-	-	-	-	-
COCFMAFH_01824	7.42e-59	-	-	-	-	-	-	-	-
COCFMAFH_01825	4.34e-45	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
COCFMAFH_01826	1.21e-135	-	-	-	L	-	-	-	Integrase
COCFMAFH_01827	4.31e-52	-	-	-	-	-	-	-	-
COCFMAFH_01828	4.04e-53	-	3.1.21.4	-	K	ko:K01155	-	ko00000,ko01000,ko02048	sequence-specific DNA binding
COCFMAFH_01829	2.68e-142	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
COCFMAFH_01831	3.66e-78	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COCFMAFH_01832	4.57e-137	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COCFMAFH_01833	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
COCFMAFH_01834	2.69e-51	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
COCFMAFH_01835	1.63e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
COCFMAFH_01836	3.88e-50	-	-	-	-	-	-	-	-
COCFMAFH_01837	1.49e-168	-	-	-	IQ	-	-	-	dehydrogenase reductase
COCFMAFH_01838	2.02e-305	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
COCFMAFH_01839	3.43e-85	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COCFMAFH_01840	1.24e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
COCFMAFH_01841	4.16e-56	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
COCFMAFH_01842	8.69e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COCFMAFH_01844	7.38e-225	ydhF	-	-	S	-	-	-	Aldo keto reductase
COCFMAFH_01845	3.75e-46	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
COCFMAFH_01846	1.57e-116	-	-	-	L	-	-	-	Helicase C-terminal domain protein
COCFMAFH_01847	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
COCFMAFH_01848	7.35e-291	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
COCFMAFH_01849	8.49e-79	-	-	-	-	-	-	-	-
COCFMAFH_01850	1.06e-10	-	-	-	S	-	-	-	Protein of unknown function, DUF536
COCFMAFH_01856	4.03e-47	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
COCFMAFH_01857	3.38e-38	-	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
COCFMAFH_01858	5.41e-193	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
COCFMAFH_01859	1.4e-300	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
COCFMAFH_01860	1.18e-200	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COCFMAFH_01861	3.3e-124	-	-	-	L	-	-	-	Integrase
COCFMAFH_01862	2.2e-70	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
COCFMAFH_01863	2.1e-50	-	-	-	K	-	-	-	Helix-turn-helix domain
COCFMAFH_01865	6.85e-294	-	-	-	-	-	-	-	-
COCFMAFH_01866	6.25e-112	-	-	-	-	-	-	-	-
COCFMAFH_01867	1.8e-84	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
COCFMAFH_01868	1.57e-56	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
COCFMAFH_01869	6.94e-117	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
COCFMAFH_01870	6.43e-182	-	-	-	T	-	-	-	EAL domain
COCFMAFH_01871	1.7e-167	-	-	-	F	-	-	-	glutamine amidotransferase
COCFMAFH_01872	1.74e-85	-	-	-	-	-	-	-	-
COCFMAFH_01873	2.22e-145	-	-	-	GM	-	-	-	NAD(P)H-binding
COCFMAFH_01874	3.43e-110	-	-	-	S	-	-	-	membrane
COCFMAFH_01875	1.28e-105	-	-	-	S	-	-	-	membrane
COCFMAFH_01876	3.14e-118	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
COCFMAFH_01877	1.14e-149	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
COCFMAFH_01878	6.58e-36	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
COCFMAFH_01879	3.02e-52	-	-	-	K	-	-	-	Transcriptional regulator
COCFMAFH_01880	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
COCFMAFH_01881	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
COCFMAFH_01882	1.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COCFMAFH_01883	7.93e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COCFMAFH_01884	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COCFMAFH_01885	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
COCFMAFH_01886	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COCFMAFH_01887	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
COCFMAFH_01888	7.15e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
COCFMAFH_01889	1.18e-51	yabO	-	-	J	-	-	-	S4 domain protein
COCFMAFH_01890	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COCFMAFH_01891	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COCFMAFH_01892	2.7e-145	-	-	-	S	-	-	-	(CBS) domain
COCFMAFH_01893	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
COCFMAFH_01894	1.12e-308	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
COCFMAFH_01895	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
COCFMAFH_01896	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
COCFMAFH_01897	1.54e-269	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COCFMAFH_01898	1.88e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COCFMAFH_01899	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
COCFMAFH_01900	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COCFMAFH_01901	1.23e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
COCFMAFH_01902	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COCFMAFH_01903	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COCFMAFH_01904	4.14e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
COCFMAFH_01905	9.59e-239	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
COCFMAFH_01906	8.02e-159	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
COCFMAFH_01907	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COCFMAFH_01908	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COCFMAFH_01909	1.06e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
COCFMAFH_01910	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
COCFMAFH_01911	2.71e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COCFMAFH_01912	1.51e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
COCFMAFH_01913	6.21e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
COCFMAFH_01914	6.08e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COCFMAFH_01915	1.37e-189	-	-	-	G	-	-	-	Right handed beta helix region
COCFMAFH_01916	2.04e-248	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
COCFMAFH_01917	1.91e-168	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
COCFMAFH_01918	4.29e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
COCFMAFH_01919	1.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
COCFMAFH_01920	6.2e-301	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COCFMAFH_01921	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COCFMAFH_01922	1.54e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
COCFMAFH_01923	4.87e-158	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
COCFMAFH_01925	4.16e-200	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
COCFMAFH_01926	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COCFMAFH_01927	7.45e-139	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
COCFMAFH_01928	4.63e-17	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
COCFMAFH_01929	6.47e-149	-	-	-	S	-	-	-	Membrane
COCFMAFH_01930	8.38e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
COCFMAFH_01931	1.99e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
COCFMAFH_01932	1.31e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
COCFMAFH_01933	4.27e-194	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
COCFMAFH_01934	1.82e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COCFMAFH_01935	3.52e-161	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
COCFMAFH_01936	9.4e-197	-	-	-	-	-	-	-	-
COCFMAFH_01937	6.13e-149	-	-	-	M	-	-	-	Glycosyl transferase
COCFMAFH_01938	3.45e-36	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	restriction
COCFMAFH_01939	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
COCFMAFH_01940	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
COCFMAFH_01941	5.18e-179	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
COCFMAFH_01942	9.22e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
COCFMAFH_01943	1.26e-60	-	-	-	-	-	-	-	-
COCFMAFH_01944	1.81e-41	-	-	-	-	-	-	-	-
COCFMAFH_01945	8.13e-123	-	-	-	S	-	-	-	PFAM Archaeal ATPase
COCFMAFH_01946	4.45e-61	-	-	-	-	-	-	-	-
COCFMAFH_01948	3.44e-47	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
COCFMAFH_01949	1.52e-205	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
COCFMAFH_01950	2.64e-315	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
COCFMAFH_01951	1.16e-114	XK27_07210	-	-	S	-	-	-	B3 4 domain
COCFMAFH_01952	8.65e-119	-	-	-	-	-	-	-	-
COCFMAFH_01953	5.13e-97	pnb	-	-	C	-	-	-	nitroreductase
COCFMAFH_01954	2.81e-69	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
COCFMAFH_01955	1.17e-149	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COCFMAFH_01962	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
COCFMAFH_01963	2e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
COCFMAFH_01964	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
COCFMAFH_01965	1.07e-170	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
COCFMAFH_01966	4.23e-67	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
COCFMAFH_01967	1.62e-232	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
COCFMAFH_01968	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
COCFMAFH_01969	1.14e-124	-	-	-	-	-	-	-	-
COCFMAFH_01970	3.09e-35	-	-	-	-	-	-	-	-
COCFMAFH_01971	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
COCFMAFH_01972	7.63e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
COCFMAFH_01974	5.29e-65	-	-	-	-	-	-	-	-
COCFMAFH_01975	2.49e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
COCFMAFH_01976	1.58e-106	-	-	-	-	-	-	-	-
COCFMAFH_01977	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COCFMAFH_01978	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
COCFMAFH_01979	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
COCFMAFH_01980	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COCFMAFH_01981	3.09e-281	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
COCFMAFH_01982	5.32e-23	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
COCFMAFH_01983	8.45e-203	rssA	-	-	S	-	-	-	Phospholipase, patatin family
COCFMAFH_01984	9.45e-152	-	-	-	L	-	-	-	Integrase
COCFMAFH_01985	3.8e-196	-	-	-	EG	-	-	-	EamA-like transporter family
COCFMAFH_01986	1.26e-243	flp	-	-	V	-	-	-	Beta-lactamase
COCFMAFH_01987	7.15e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
COCFMAFH_01988	5.66e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
COCFMAFH_01989	1.3e-50	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
COCFMAFH_01990	1.08e-89	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
COCFMAFH_01992	1.5e-149	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
COCFMAFH_01993	4.53e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
COCFMAFH_01994	7.73e-98	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
COCFMAFH_01995	5.12e-266	yacL	-	-	S	-	-	-	domain protein
COCFMAFH_01996	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COCFMAFH_01997	1.1e-125	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
COCFMAFH_01998	3.33e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
COCFMAFH_01999	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COCFMAFH_02000	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
COCFMAFH_02001	3.51e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
COCFMAFH_02002	5.84e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_02003	9.62e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COCFMAFH_02004	2.47e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
COCFMAFH_02005	6.27e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
COCFMAFH_02006	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COCFMAFH_02007	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
COCFMAFH_02008	5.27e-235	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
COCFMAFH_02009	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
COCFMAFH_02011	1.36e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
COCFMAFH_02012	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
COCFMAFH_02013	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COCFMAFH_02014	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COCFMAFH_02015	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
COCFMAFH_02016	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
COCFMAFH_02017	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
COCFMAFH_02018	0.0	-	-	-	EGP	-	-	-	Major Facilitator
COCFMAFH_02019	1.55e-143	-	-	-	-	-	-	-	-
COCFMAFH_02022	1.85e-202	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
COCFMAFH_02023	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
COCFMAFH_02026	2.12e-61	-	-	-	C	-	-	-	Oxidoreductase
COCFMAFH_02027	3.91e-26	-	-	-	C	-	-	-	Oxidoreductase
COCFMAFH_02028	2.89e-68	-	-	-	C	-	-	-	Oxidoreductase
COCFMAFH_02029	3.88e-71	-	-	-	S	-	-	-	macrophage migration inhibitory factor
COCFMAFH_02030	4.07e-85	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
COCFMAFH_02031	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COCFMAFH_02033	3.66e-286	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
COCFMAFH_02036	3e-93	-	-	-	-	-	-	-	-
COCFMAFH_02037	1.88e-290	-	-	-	P	-	-	-	Chloride transporter, ClC family
COCFMAFH_02038	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
COCFMAFH_02039	5.65e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
COCFMAFH_02041	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COCFMAFH_02043	8.9e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
COCFMAFH_02044	7.37e-275	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
COCFMAFH_02045	3.98e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COCFMAFH_02046	5.07e-120	-	-	-	-	-	-	-	-
COCFMAFH_02047	7.34e-86	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
COCFMAFH_02048	2.45e-222	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
COCFMAFH_02049	1.28e-196	epsB	-	-	M	-	-	-	biosynthesis protein
COCFMAFH_02050	3.18e-160	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
COCFMAFH_02051	7.75e-148	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
COCFMAFH_02052	7.93e-90	-	-	-	L	-	-	-	Integrase
COCFMAFH_02053	1.55e-155	-	-	-	S	-	-	-	KAP family P-loop domain
COCFMAFH_02054	1.26e-24	-	-	-	-	-	-	-	-
COCFMAFH_02055	1.38e-10	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
COCFMAFH_02056	9.7e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
COCFMAFH_02057	6.63e-281	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
COCFMAFH_02058	2.16e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
COCFMAFH_02059	5.28e-76	-	-	-	-	-	-	-	-
COCFMAFH_02061	1.3e-37	pre	-	-	D	-	-	-	plasmid recombination enzyme
COCFMAFH_02062	1.52e-144	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
COCFMAFH_02063	3.31e-66	-	-	-	S	-	-	-	Plasmid replication protein
COCFMAFH_02065	6.57e-121	-	-	-	J	-	-	-	Aminoglycoside-2''-adenylyltransferase
COCFMAFH_02066	9.82e-20	pre	-	-	D	-	-	-	plasmid recombination enzyme
COCFMAFH_02067	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
COCFMAFH_02068	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COCFMAFH_02069	3.28e-156	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COCFMAFH_02070	2.41e-264	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
COCFMAFH_02071	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COCFMAFH_02072	2.47e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COCFMAFH_02073	9.73e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COCFMAFH_02074	1.43e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COCFMAFH_02075	6.12e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COCFMAFH_02076	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COCFMAFH_02077	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
COCFMAFH_02078	3.46e-78	-	-	-	L	-	-	-	Resolvase, N terminal domain
COCFMAFH_02079	9.7e-162	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
COCFMAFH_02080	8.75e-146	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COCFMAFH_02082	5.54e-216	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
COCFMAFH_02083	3.21e-214	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
COCFMAFH_02084	1.53e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
COCFMAFH_02085	1.05e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
COCFMAFH_02086	1.2e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
COCFMAFH_02087	3.46e-09	-	-	-	EG	-	-	-	EamA-like transporter family
COCFMAFH_02088	4.28e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
COCFMAFH_02089	4.06e-103	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
COCFMAFH_02090	3.85e-24	-	-	-	S	-	-	-	PFAM Archaeal ATPase
COCFMAFH_02091	1.86e-227	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COCFMAFH_02092	1.64e-23	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
COCFMAFH_02093	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_02094	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COCFMAFH_02095	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
COCFMAFH_02096	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COCFMAFH_02097	9.16e-111	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COCFMAFH_02098	3.02e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
COCFMAFH_02099	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
COCFMAFH_02100	6.09e-310	-	-	-	E	-	-	-	amino acid
COCFMAFH_02101	2.6e-179	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
COCFMAFH_02102	9.75e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
COCFMAFH_02103	2.17e-213	-	-	-	GK	-	-	-	ROK family
COCFMAFH_02104	0.0	fusA1	-	-	J	-	-	-	elongation factor G
COCFMAFH_02105	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
COCFMAFH_02106	1.42e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
COCFMAFH_02107	1.78e-83	-	-	-	-	-	-	-	-
COCFMAFH_02108	3.18e-11	-	-	-	-	-	-	-	-
COCFMAFH_02109	6.79e-271	-	-	-	EGP	-	-	-	Major Facilitator
COCFMAFH_02110	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
COCFMAFH_02111	9.77e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
COCFMAFH_02112	3.46e-207	-	-	-	-	-	-	-	-
COCFMAFH_02113	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
COCFMAFH_02114	2.53e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
COCFMAFH_02115	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
COCFMAFH_02116	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
COCFMAFH_02117	6.5e-71	-	-	-	-	-	-	-	-
COCFMAFH_02118	2.91e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
COCFMAFH_02119	4.68e-314	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COCFMAFH_02120	8.59e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
COCFMAFH_02121	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
COCFMAFH_02122	7.72e-178	-	-	-	IQ	-	-	-	KR domain
COCFMAFH_02123	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
COCFMAFH_02124	9.79e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase