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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
CKHKLAEA_00002	2.6e-121	-	-	-	L	-	-	-	Integrase
CKHKLAEA_00004	1.25e-201	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
CKHKLAEA_00005	3.38e-100	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
CKHKLAEA_00007	8.16e-67	-	-	-	-	-	-	-	-
CKHKLAEA_00012	1.75e-225	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
CKHKLAEA_00013	1.54e-76	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
CKHKLAEA_00014	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
CKHKLAEA_00015	6.08e-107	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
CKHKLAEA_00016	3e-93	-	-	-	-	-	-	-	-
CKHKLAEA_00018	4.17e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CKHKLAEA_00019	1.65e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKHKLAEA_00020	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_00021	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CKHKLAEA_00022	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CKHKLAEA_00023	1.65e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CKHKLAEA_00024	3.02e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
CKHKLAEA_00025	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
CKHKLAEA_00026	1.05e-310	-	-	-	E	-	-	-	amino acid
CKHKLAEA_00027	4.49e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
CKHKLAEA_00028	2.4e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CKHKLAEA_00029	2.17e-213	-	-	-	GK	-	-	-	ROK family
CKHKLAEA_00030	0.0	fusA1	-	-	J	-	-	-	elongation factor G
CKHKLAEA_00031	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
CKHKLAEA_00032	1.42e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
CKHKLAEA_00033	1.78e-83	-	-	-	-	-	-	-	-
CKHKLAEA_00034	3.18e-11	-	-	-	-	-	-	-	-
CKHKLAEA_00035	6.79e-271	-	-	-	EGP	-	-	-	Major Facilitator
CKHKLAEA_00036	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
CKHKLAEA_00037	9.77e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
CKHKLAEA_00038	3.46e-207	-	-	-	-	-	-	-	-
CKHKLAEA_00039	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
CKHKLAEA_00040	2.53e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
CKHKLAEA_00041	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
CKHKLAEA_00042	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CKHKLAEA_00043	6.5e-71	-	-	-	-	-	-	-	-
CKHKLAEA_00044	2.91e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CKHKLAEA_00045	4.68e-314	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_00046	8.59e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
CKHKLAEA_00047	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CKHKLAEA_00048	7.72e-178	-	-	-	IQ	-	-	-	KR domain
CKHKLAEA_00049	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
CKHKLAEA_00050	3.42e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
CKHKLAEA_00051	5e-194	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CKHKLAEA_00052	7.67e-162	-	-	-	L	-	-	-	Helix-turn-helix domain
CKHKLAEA_00053	1.86e-62	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
CKHKLAEA_00054	9.45e-152	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
CKHKLAEA_00055	2.59e-135	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CKHKLAEA_00056	3.16e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CKHKLAEA_00057	0.0	-	-	-	L	-	-	-	DNA helicase
CKHKLAEA_00058	7.04e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
CKHKLAEA_00059	5.96e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
CKHKLAEA_00060	5.54e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CKHKLAEA_00061	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CKHKLAEA_00062	2.08e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
CKHKLAEA_00063	1.09e-227	-	-	-	-	-	-	-	-
CKHKLAEA_00064	5.9e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
CKHKLAEA_00065	3.45e-198	-	-	-	KL	-	-	-	DNA methylase
CKHKLAEA_00066	5.98e-303	isp	-	-	L	-	-	-	Transposase
CKHKLAEA_00067	4.88e-244	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CKHKLAEA_00068	7.71e-50	-	-	-	L	-	-	-	Initiator Replication protein
CKHKLAEA_00069	1.04e-72	-	-	-	S	-	-	-	Phage head-tail joining protein
CKHKLAEA_00070	5.95e-92	-	-	-	S	-	-	-	Bacteriophage holin family
CKHKLAEA_00072	9.3e-160	ywfI	-	-	S	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	Chlorite dismutase
CKHKLAEA_00074	3.98e-32	-	-	-	S	-	-	-	helicase activity
CKHKLAEA_00075	2.17e-57	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
CKHKLAEA_00076	8.74e-211	-	-	-	S	-	-	-	Phage capsid family
CKHKLAEA_00077	9.18e-140	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
CKHKLAEA_00078	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CKHKLAEA_00079	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
CKHKLAEA_00080	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
CKHKLAEA_00081	7.51e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
CKHKLAEA_00082	5.9e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
CKHKLAEA_00083	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
CKHKLAEA_00084	5.9e-233	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKHKLAEA_00085	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
CKHKLAEA_00086	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CKHKLAEA_00087	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
CKHKLAEA_00088	4.23e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CKHKLAEA_00089	1.83e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CKHKLAEA_00090	1.18e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
CKHKLAEA_00091	5.46e-297	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
CKHKLAEA_00092	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CKHKLAEA_00093	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CKHKLAEA_00094	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
CKHKLAEA_00095	1.68e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
CKHKLAEA_00096	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
CKHKLAEA_00097	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
CKHKLAEA_00098	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CKHKLAEA_00099	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CKHKLAEA_00100	4.95e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CKHKLAEA_00101	5.19e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
CKHKLAEA_00102	1.79e-84	-	-	-	-	-	-	-	-
CKHKLAEA_00103	1.13e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CKHKLAEA_00104	5.24e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CKHKLAEA_00105	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
CKHKLAEA_00106	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CKHKLAEA_00107	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CKHKLAEA_00108	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CKHKLAEA_00109	2.39e-253	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
CKHKLAEA_00111	4.78e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CKHKLAEA_00113	7.92e-76	-	-	-	-	-	-	-	-
CKHKLAEA_00114	4.65e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
CKHKLAEA_00115	1.66e-165	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CKHKLAEA_00116	4.8e-72	-	-	-	-	-	-	-	-
CKHKLAEA_00117	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CKHKLAEA_00118	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CKHKLAEA_00119	2.09e-211	-	-	-	G	-	-	-	Phosphotransferase enzyme family
CKHKLAEA_00120	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CKHKLAEA_00121	6.06e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_00122	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CKHKLAEA_00123	8.25e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
CKHKLAEA_00124	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
CKHKLAEA_00125	5.21e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CKHKLAEA_00126	4.85e-245	isp	-	-	L	-	-	-	Transposase
CKHKLAEA_00127	2.76e-198	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
CKHKLAEA_00128	1.4e-53	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CKHKLAEA_00129	3.35e-59	-	-	-	S	-	-	-	Pfam:DUF59
CKHKLAEA_00130	1.68e-91	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CKHKLAEA_00131	8.48e-20	-	-	-	M	-	-	-	Glycosyl transferase family 8
CKHKLAEA_00132	4.14e-59	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CKHKLAEA_00133	8.13e-119	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CKHKLAEA_00134	1.15e-26	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
CKHKLAEA_00135	1.55e-45	arbV	-	-	I	-	-	-	Phosphate acyltransferases
CKHKLAEA_00137	5.34e-136	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CKHKLAEA_00138	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CKHKLAEA_00139	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
CKHKLAEA_00140	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CKHKLAEA_00141	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CKHKLAEA_00142	3.43e-189	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
CKHKLAEA_00143	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CKHKLAEA_00144	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CKHKLAEA_00145	9.61e-137	-	-	-	-	-	-	-	-
CKHKLAEA_00146	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CKHKLAEA_00147	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
CKHKLAEA_00148	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
CKHKLAEA_00149	1.46e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CKHKLAEA_00150	3.55e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
CKHKLAEA_00151	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CKHKLAEA_00152	2.76e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
CKHKLAEA_00153	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKHKLAEA_00154	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CKHKLAEA_00155	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
CKHKLAEA_00156	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CKHKLAEA_00157	7.48e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
CKHKLAEA_00158	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CKHKLAEA_00159	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CKHKLAEA_00160	5.17e-70	-	-	-	-	-	-	-	-
CKHKLAEA_00161	0.0	oatA	-	-	I	-	-	-	Acyltransferase
CKHKLAEA_00162	3.7e-106	-	-	-	K	-	-	-	Transcriptional regulator
CKHKLAEA_00163	4.01e-193	-	-	-	S	-	-	-	Cof-like hydrolase
CKHKLAEA_00164	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
CKHKLAEA_00166	2.7e-172	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
CKHKLAEA_00167	0.0	yclK	-	-	T	-	-	-	Histidine kinase
CKHKLAEA_00168	2.71e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
CKHKLAEA_00169	6.42e-140	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
CKHKLAEA_00170	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
CKHKLAEA_00171	2.49e-39	-	-	-	-	-	-	-	-
CKHKLAEA_00172	2.08e-208	xylR	-	-	GK	-	-	-	ROK family
CKHKLAEA_00173	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
CKHKLAEA_00174	3.05e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
CKHKLAEA_00175	3.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CKHKLAEA_00176	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
CKHKLAEA_00177	1.82e-316	-	-	-	E	ko:K03294	-	ko00000	amino acid
CKHKLAEA_00178	6.2e-271	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
CKHKLAEA_00179	1.22e-288	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
CKHKLAEA_00181	5.95e-238	-	-	-	L	-	-	-	PFAM Integrase catalytic region
CKHKLAEA_00183	9.7e-94	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
CKHKLAEA_00184	7.1e-56	XK27_03440	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
CKHKLAEA_00185	7.41e-163	-	-	-	-	-	-	-	-
CKHKLAEA_00186	1.06e-91	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
CKHKLAEA_00187	8.56e-161	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CKHKLAEA_00188	6.52e-198	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CKHKLAEA_00189	1.4e-34	-	-	-	K	-	-	-	TRANSCRIPTIONal
CKHKLAEA_00190	1.65e-83	yju3	-	-	I	-	-	-	Serine aminopeptidase, S33
CKHKLAEA_00191	1.56e-102	pncA	-	-	Q	-	-	-	Isochorismatase family
CKHKLAEA_00192	1.5e-289	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CKHKLAEA_00193	1.76e-143	-	-	-	F	-	-	-	NUDIX domain
CKHKLAEA_00194	2.46e-159	-	-	-	L	-	-	-	PFAM Integrase catalytic region
CKHKLAEA_00195	8.13e-123	-	-	-	S	-	-	-	PFAM Archaeal ATPase
CKHKLAEA_00196	3.81e-62	-	-	-	-	-	-	-	-
CKHKLAEA_00198	3.44e-47	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
CKHKLAEA_00199	1.52e-205	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
CKHKLAEA_00200	2.64e-315	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
CKHKLAEA_00201	1.65e-114	XK27_07210	-	-	S	-	-	-	B3 4 domain
CKHKLAEA_00202	8.65e-119	-	-	-	-	-	-	-	-
CKHKLAEA_00203	1.25e-157	pnb	-	-	C	-	-	-	nitroreductase
CKHKLAEA_00204	3.43e-96	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
CKHKLAEA_00205	2.36e-217	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
CKHKLAEA_00206	7.88e-215	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
CKHKLAEA_00207	1.53e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
CKHKLAEA_00208	1.05e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
CKHKLAEA_00209	4.9e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
CKHKLAEA_00210	5.18e-27	-	-	-	-	-	-	-	-
CKHKLAEA_00211	6.48e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
CKHKLAEA_00212	2.25e-105	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
CKHKLAEA_00213	2.87e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
CKHKLAEA_00214	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
CKHKLAEA_00215	1.86e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CKHKLAEA_00216	1.25e-136	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
CKHKLAEA_00217	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
CKHKLAEA_00218	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
CKHKLAEA_00219	7.11e-293	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
CKHKLAEA_00221	2.09e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CKHKLAEA_00222	2.02e-72	-	-	-	-	-	-	-	-
CKHKLAEA_00223	4.94e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
CKHKLAEA_00224	1.58e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
CKHKLAEA_00225	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
CKHKLAEA_00226	3.98e-280	arcT	-	-	E	-	-	-	Aminotransferase
CKHKLAEA_00227	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
CKHKLAEA_00228	0.0	potE	-	-	E	-	-	-	Amino Acid
CKHKLAEA_00229	7.47e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
CKHKLAEA_00230	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
CKHKLAEA_00231	2.53e-42	-	-	-	-	-	-	-	-
CKHKLAEA_00232	2.02e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
CKHKLAEA_00233	1.84e-187	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
CKHKLAEA_00234	1.38e-225	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
CKHKLAEA_00235	1.15e-152	-	-	-	M	-	-	-	Bacterial sugar transferase
CKHKLAEA_00236	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
CKHKLAEA_00237	1.22e-190	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CKHKLAEA_00238	7.7e-29	-	-	-	G	-	-	-	Right handed beta helix region
CKHKLAEA_00239	4.71e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
CKHKLAEA_00240	1.39e-139	-	-	-	LM	-	-	-	gp58-like protein
CKHKLAEA_00242	6.74e-35	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
CKHKLAEA_00243	2.05e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
CKHKLAEA_00244	1.66e-303	-	-	-	T	-	-	-	GHKL domain
CKHKLAEA_00245	1.87e-138	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
CKHKLAEA_00246	1.2e-91	-	-	-	P	-	-	-	FAD-binding domain
CKHKLAEA_00247	1.16e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
CKHKLAEA_00248	1.2e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CKHKLAEA_00249	4.09e-99	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CKHKLAEA_00250	2.32e-210	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
CKHKLAEA_00251	7.88e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
CKHKLAEA_00252	2.67e-111	-	-	-	C	-	-	-	Flavodoxin
CKHKLAEA_00253	1.45e-201	lysR	-	-	K	-	-	-	Transcriptional regulator
CKHKLAEA_00254	7.41e-114	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
CKHKLAEA_00255	8.09e-44	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
CKHKLAEA_00256	2.05e-195	-	-	-	S	-	-	-	Alpha beta hydrolase
CKHKLAEA_00257	5.88e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
CKHKLAEA_00258	1.02e-120	-	-	-	K	-	-	-	Virulence activator alpha C-term
CKHKLAEA_00259	1.39e-83	-	-	-	GM	-	-	-	NAD(P)H-binding
CKHKLAEA_00260	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
CKHKLAEA_00261	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
CKHKLAEA_00262	5.61e-75	-	-	-	K	-	-	-	Transcriptional regulator
CKHKLAEA_00263	3.02e-52	-	-	-	K	-	-	-	Transcriptional regulator
CKHKLAEA_00264	7.26e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
CKHKLAEA_00265	6.78e-136	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
CKHKLAEA_00266	1.28e-105	-	-	-	S	-	-	-	membrane
CKHKLAEA_00267	3.43e-110	-	-	-	S	-	-	-	membrane
CKHKLAEA_00268	2.22e-145	-	-	-	GM	-	-	-	NAD(P)H-binding
CKHKLAEA_00269	1.74e-85	-	-	-	-	-	-	-	-
CKHKLAEA_00270	4.18e-168	-	-	-	F	-	-	-	glutamine amidotransferase
CKHKLAEA_00271	5.28e-181	-	-	-	T	-	-	-	EAL domain
CKHKLAEA_00272	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
CKHKLAEA_00273	7.01e-109	-	-	-	-	-	-	-	-
CKHKLAEA_00274	1.13e-259	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
CKHKLAEA_00275	6.11e-158	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CKHKLAEA_00276	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
CKHKLAEA_00277	1.43e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
CKHKLAEA_00278	5.35e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
CKHKLAEA_00279	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
CKHKLAEA_00280	7.17e-146	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
CKHKLAEA_00281	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
CKHKLAEA_00282	7.6e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CKHKLAEA_00283	1.61e-291	-	-	-	-	-	-	-	-
CKHKLAEA_00284	6.71e-102	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CKHKLAEA_00285	2.74e-139	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
CKHKLAEA_00286	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CKHKLAEA_00287	7.48e-155	-	-	-	GM	-	-	-	NmrA-like family
CKHKLAEA_00288	5.36e-92	-	-	-	S	ko:K02348	-	ko00000	Gnat family
CKHKLAEA_00289	1.89e-51	-	-	-	S	-	-	-	Cytochrome B5
CKHKLAEA_00290	7.08e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
CKHKLAEA_00291	6.17e-104	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
CKHKLAEA_00293	1.9e-98	-	-	-	L	-	-	-	Integrase
CKHKLAEA_00295	1.83e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
CKHKLAEA_00296	1.03e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
CKHKLAEA_00297	2.87e-171	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CKHKLAEA_00298	9.28e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
CKHKLAEA_00299	1.08e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CKHKLAEA_00300	4.18e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CKHKLAEA_00301	2.07e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
CKHKLAEA_00303	9.32e-92	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
CKHKLAEA_00304	1.61e-54	-	-	-	-	-	-	-	-
CKHKLAEA_00305	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
CKHKLAEA_00306	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
CKHKLAEA_00307	2.49e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
CKHKLAEA_00308	4.67e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
CKHKLAEA_00309	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
CKHKLAEA_00310	1.15e-178	-	-	-	-	-	-	-	-
CKHKLAEA_00311	1.63e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
CKHKLAEA_00312	1.26e-268	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CKHKLAEA_00313	1.84e-75	-	-	-	-	-	-	-	-
CKHKLAEA_00314	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CKHKLAEA_00315	6.23e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
CKHKLAEA_00316	1.1e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
CKHKLAEA_00317	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
CKHKLAEA_00318	9.81e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
CKHKLAEA_00319	3.33e-133	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CKHKLAEA_00320	2.58e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
CKHKLAEA_00321	1.01e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
CKHKLAEA_00322	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CKHKLAEA_00323	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CKHKLAEA_00324	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
CKHKLAEA_00325	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
CKHKLAEA_00326	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CKHKLAEA_00327	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
CKHKLAEA_00328	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CKHKLAEA_00329	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CKHKLAEA_00330	6.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
CKHKLAEA_00331	7.54e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CKHKLAEA_00332	1.25e-241	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CKHKLAEA_00333	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CKHKLAEA_00334	1.51e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CKHKLAEA_00335	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CKHKLAEA_00336	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CKHKLAEA_00337	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
CKHKLAEA_00338	7.58e-83	-	-	-	M	-	-	-	Glycosyl transferase, family 2
CKHKLAEA_00340	9.92e-168	-	-	-	S	-	-	-	overlaps another CDS with the same product name
CKHKLAEA_00341	3.43e-85	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CKHKLAEA_00342	4.57e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
CKHKLAEA_00343	4.52e-86	xtmA	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
CKHKLAEA_00348	8.81e-89	-	-	-	K	-	-	-	Transcriptional regulator
CKHKLAEA_00349	4.03e-299	-	-	-	EGP	-	-	-	Major Facilitator
CKHKLAEA_00350	3.85e-144	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
CKHKLAEA_00351	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
CKHKLAEA_00352	1.73e-148	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
CKHKLAEA_00353	1.18e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CKHKLAEA_00354	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CKHKLAEA_00355	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CKHKLAEA_00356	2.11e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
CKHKLAEA_00357	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
CKHKLAEA_00358	5.62e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CKHKLAEA_00359	3.31e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CKHKLAEA_00360	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
CKHKLAEA_00361	1.79e-214	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
CKHKLAEA_00362	8.36e-174	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
CKHKLAEA_00363	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
CKHKLAEA_00364	1.43e-208	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
CKHKLAEA_00365	9.67e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CKHKLAEA_00366	7.73e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CKHKLAEA_00367	5.89e-201	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
CKHKLAEA_00368	2.34e-113	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
CKHKLAEA_00369	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CKHKLAEA_00370	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
CKHKLAEA_00371	4.16e-19	-	-	-	-	-	-	-	-
CKHKLAEA_00372	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CKHKLAEA_00373	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CKHKLAEA_00374	5.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
CKHKLAEA_00375	8.05e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
CKHKLAEA_00376	5.73e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
CKHKLAEA_00377	1.94e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
CKHKLAEA_00379	1.83e-21	-	-	-	-	-	-	-	-
CKHKLAEA_00380	5.58e-306	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
CKHKLAEA_00381	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CKHKLAEA_00383	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CKHKLAEA_00384	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
CKHKLAEA_00385	1.68e-103	pduO	-	-	S	-	-	-	Haem-degrading
CKHKLAEA_00387	1.26e-96	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
CKHKLAEA_00389	2.87e-30	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
CKHKLAEA_00390	1.92e-61	-	-	-	S	-	-	-	Phage antirepressor protein KilAC domain
CKHKLAEA_00391	4.69e-251	yagE	-	-	E	-	-	-	amino acid
CKHKLAEA_00392	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
CKHKLAEA_00393	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
CKHKLAEA_00394	8.65e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CKHKLAEA_00395	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CKHKLAEA_00396	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CKHKLAEA_00397	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CKHKLAEA_00398	4.43e-183	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CKHKLAEA_00399	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CKHKLAEA_00400	1.97e-293	-	-	-	-	-	-	-	-
CKHKLAEA_00401	1.77e-298	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
CKHKLAEA_00402	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
CKHKLAEA_00403	3.59e-97	-	-	-	F	-	-	-	Nudix hydrolase
CKHKLAEA_00404	2.75e-132	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
CKHKLAEA_00405	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
CKHKLAEA_00406	6.02e-34	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
CKHKLAEA_00407	4.65e-193	-	-	-	-	-	-	-	-
CKHKLAEA_00408	8.65e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
CKHKLAEA_00409	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
CKHKLAEA_00410	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
CKHKLAEA_00411	3.17e-233	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKHKLAEA_00412	6.08e-13	-	-	-	S	-	-	-	CsbD-like
CKHKLAEA_00413	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
CKHKLAEA_00414	1.27e-291	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CKHKLAEA_00415	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
CKHKLAEA_00416	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
CKHKLAEA_00417	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CKHKLAEA_00418	6.85e-44	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
CKHKLAEA_00419	1.77e-202	-	-	-	EG	-	-	-	EamA-like transporter family
CKHKLAEA_00420	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CKHKLAEA_00421	3.39e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
CKHKLAEA_00422	1.65e-286	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
CKHKLAEA_00424	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
CKHKLAEA_00425	9.19e-91	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
CKHKLAEA_00426	8.06e-76	-	-	-	-	-	-	-	-
CKHKLAEA_00427	1.77e-55	-	-	-	-	-	-	-	-
CKHKLAEA_00428	3.44e-12	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
CKHKLAEA_00429	6.22e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
CKHKLAEA_00430	3.85e-72	-	-	-	-	-	-	-	-
CKHKLAEA_00431	5.34e-269	yttB	-	-	EGP	-	-	-	Major Facilitator
CKHKLAEA_00432	6.04e-307	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
CKHKLAEA_00433	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CKHKLAEA_00434	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
CKHKLAEA_00435	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CKHKLAEA_00436	2.7e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CKHKLAEA_00437	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
CKHKLAEA_00438	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CKHKLAEA_00439	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CKHKLAEA_00440	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CKHKLAEA_00441	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
CKHKLAEA_00442	9.78e-14	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
CKHKLAEA_00443	1.13e-104	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
CKHKLAEA_00444	1.41e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CKHKLAEA_00445	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CKHKLAEA_00446	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
CKHKLAEA_00447	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CKHKLAEA_00448	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CKHKLAEA_00449	2.55e-169	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
CKHKLAEA_00450	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CKHKLAEA_00451	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CKHKLAEA_00452	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
CKHKLAEA_00453	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKHKLAEA_00454	7.33e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
CKHKLAEA_00455	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CKHKLAEA_00456	4.4e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
CKHKLAEA_00457	3.88e-205	-	-	-	S	-	-	-	reductase
CKHKLAEA_00459	0.0	-	-	-	S	-	-	-	amidohydrolase
CKHKLAEA_00460	2.55e-192	-	-	-	K	-	-	-	Aminotransferase class I and II
CKHKLAEA_00461	4.47e-74	-	-	-	K	-	-	-	Aminotransferase class I and II
CKHKLAEA_00462	3.17e-18	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
CKHKLAEA_00464	1.51e-34	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CKHKLAEA_00465	7.62e-54	-	-	-	-	-	-	-	-
CKHKLAEA_00466	6.74e-88	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
CKHKLAEA_00467	2.86e-68	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
CKHKLAEA_00468	1.49e-103	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
CKHKLAEA_00470	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
CKHKLAEA_00471	1.24e-65	-	-	-	-	-	-	-	-
CKHKLAEA_00472	3.05e-86	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CKHKLAEA_00473	5.79e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
CKHKLAEA_00474	1.21e-303	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CKHKLAEA_00475	1.25e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
CKHKLAEA_00476	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CKHKLAEA_00477	4.29e-119	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
CKHKLAEA_00478	2.71e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CKHKLAEA_00479	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
CKHKLAEA_00480	1.45e-55	-	-	-	-	-	-	-	-
CKHKLAEA_00481	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CKHKLAEA_00482	1.61e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CKHKLAEA_00483	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
CKHKLAEA_00484	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
CKHKLAEA_00485	1.11e-224	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CKHKLAEA_00486	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
CKHKLAEA_00487	3.08e-146	-	-	-	-	-	-	-	-
CKHKLAEA_00488	8.42e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
CKHKLAEA_00489	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKHKLAEA_00490	1.52e-43	-	-	-	-	-	-	-	-
CKHKLAEA_00491	4.68e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CKHKLAEA_00492	2.17e-57	-	-	-	-	-	-	-	-
CKHKLAEA_00494	6.82e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CKHKLAEA_00495	4.71e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
CKHKLAEA_00496	2.76e-135	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
CKHKLAEA_00497	8.17e-285	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
CKHKLAEA_00498	2.97e-136	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
CKHKLAEA_00499	1.62e-277	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
CKHKLAEA_00500	9.3e-61	-	-	-	-	-	-	-	-
CKHKLAEA_00501	1.49e-54	-	-	-	-	-	-	-	-
CKHKLAEA_00503	3.88e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CKHKLAEA_00504	2.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CKHKLAEA_00506	6.56e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
CKHKLAEA_00507	8.5e-208	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
CKHKLAEA_00508	1.53e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CKHKLAEA_00509	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CKHKLAEA_00510	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
CKHKLAEA_00511	7.76e-74	-	-	-	-	-	-	-	-
CKHKLAEA_00512	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
CKHKLAEA_00513	9.31e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CKHKLAEA_00514	3.47e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
CKHKLAEA_00515	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CKHKLAEA_00516	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CKHKLAEA_00517	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CKHKLAEA_00518	1.45e-260	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CKHKLAEA_00519	8.69e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CKHKLAEA_00520	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CKHKLAEA_00521	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CKHKLAEA_00522	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CKHKLAEA_00523	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
CKHKLAEA_00524	8.04e-185	ylmH	-	-	S	-	-	-	S4 domain protein
CKHKLAEA_00525	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
CKHKLAEA_00526	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CKHKLAEA_00527	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CKHKLAEA_00528	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
CKHKLAEA_00529	1.54e-33	-	-	-	-	-	-	-	-
CKHKLAEA_00530	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CKHKLAEA_00531	1.75e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CKHKLAEA_00532	1.13e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
CKHKLAEA_00533	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CKHKLAEA_00534	6.67e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
CKHKLAEA_00535	3.82e-157	-	-	-	S	-	-	-	repeat protein
CKHKLAEA_00536	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CKHKLAEA_00537	8.58e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CKHKLAEA_00538	1.08e-05	-	-	-	L	-	-	-	Helix-turn-helix domain
CKHKLAEA_00539	3.1e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
CKHKLAEA_00540	2e-205	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CKHKLAEA_00541	3.66e-38	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CKHKLAEA_00542	3.17e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CKHKLAEA_00543	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
CKHKLAEA_00544	1.45e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CKHKLAEA_00545	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CKHKLAEA_00546	1.64e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CKHKLAEA_00547	9.32e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKHKLAEA_00548	1.43e-177	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CKHKLAEA_00549	1.62e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CKHKLAEA_00550	2.58e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CKHKLAEA_00551	5.77e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
CKHKLAEA_00552	6.63e-281	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
CKHKLAEA_00553	7.55e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
CKHKLAEA_00554	5.28e-76	-	-	-	-	-	-	-	-
CKHKLAEA_00556	3.3e-265	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CKHKLAEA_00557	4.37e-39	-	-	-	-	-	-	-	-
CKHKLAEA_00558	1.69e-229	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
CKHKLAEA_00559	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
CKHKLAEA_00560	6.08e-102	-	-	-	-	-	-	-	-
CKHKLAEA_00561	1.38e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CKHKLAEA_00562	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
CKHKLAEA_00563	9.42e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
CKHKLAEA_00564	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CKHKLAEA_00565	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
CKHKLAEA_00566	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
CKHKLAEA_00567	3.52e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
CKHKLAEA_00568	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
CKHKLAEA_00569	7.54e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
CKHKLAEA_00570	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
CKHKLAEA_00571	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
CKHKLAEA_00572	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CKHKLAEA_00573	3.51e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
CKHKLAEA_00574	3.4e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
CKHKLAEA_00575	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
CKHKLAEA_00576	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
CKHKLAEA_00577	9.21e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
CKHKLAEA_00578	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
CKHKLAEA_00579	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CKHKLAEA_00580	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CKHKLAEA_00581	3.58e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
CKHKLAEA_00582	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CKHKLAEA_00583	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CKHKLAEA_00584	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CKHKLAEA_00585	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
CKHKLAEA_00586	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
CKHKLAEA_00587	2.44e-20	-	-	-	-	-	-	-	-
CKHKLAEA_00588	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CKHKLAEA_00589	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CKHKLAEA_00590	3.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CKHKLAEA_00591	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
CKHKLAEA_00592	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
CKHKLAEA_00593	1.46e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CKHKLAEA_00594	1.79e-121	-	-	-	-	-	-	-	-
CKHKLAEA_00596	7.77e-159	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CKHKLAEA_00597	3.77e-93	-	-	-	S	-	-	-	Phage tail tube protein, TTP
CKHKLAEA_00598	3.91e-23	-	-	-	M	-	-	-	KxYKxGKxW signal domain protein
CKHKLAEA_00599	7.64e-47	yeeC	-	-	P	-	-	-	T5orf172
CKHKLAEA_00600	2.79e-179	-	-	-	K	-	-	-	LysR substrate binding domain
CKHKLAEA_00601	6.04e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
CKHKLAEA_00602	1.83e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CKHKLAEA_00603	1.95e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CKHKLAEA_00604	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CKHKLAEA_00605	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CKHKLAEA_00606	7.47e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
CKHKLAEA_00607	4.34e-121	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKHKLAEA_00608	1.15e-301	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
CKHKLAEA_00609	6.76e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
CKHKLAEA_00610	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
CKHKLAEA_00611	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
CKHKLAEA_00612	9.77e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
CKHKLAEA_00613	3.65e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CKHKLAEA_00614	3.78e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CKHKLAEA_00615	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CKHKLAEA_00616	7.43e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
CKHKLAEA_00617	2.23e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CKHKLAEA_00618	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CKHKLAEA_00619	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CKHKLAEA_00620	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CKHKLAEA_00621	3.62e-246	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
CKHKLAEA_00622	8.26e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CKHKLAEA_00623	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
CKHKLAEA_00624	4.57e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
CKHKLAEA_00625	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CKHKLAEA_00626	3.14e-233	-	-	-	-	-	-	-	-
CKHKLAEA_00627	4.92e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CKHKLAEA_00628	5.39e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
CKHKLAEA_00632	2.69e-165	-	-	-	M	-	-	-	PFAM NLP P60 protein
CKHKLAEA_00633	3.16e-233	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CKHKLAEA_00634	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CKHKLAEA_00635	5.63e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_00636	3.2e-118	-	-	-	P	-	-	-	Cadmium resistance transporter
CKHKLAEA_00637	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
CKHKLAEA_00638	1.05e-44	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CKHKLAEA_00639	7.25e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
CKHKLAEA_00640	4.38e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CKHKLAEA_00641	3.1e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
CKHKLAEA_00642	8.16e-212	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
CKHKLAEA_00643	2.35e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
CKHKLAEA_00644	0.0	-	-	-	L	-	-	-	Transposase
CKHKLAEA_00645	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CKHKLAEA_00646	4.79e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
CKHKLAEA_00647	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
CKHKLAEA_00648	3.98e-304	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
CKHKLAEA_00649	3.39e-33	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
CKHKLAEA_00650	3.18e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
CKHKLAEA_00651	1.77e-56	-	-	-	-	-	-	-	-
CKHKLAEA_00652	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CKHKLAEA_00653	2.84e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
CKHKLAEA_00654	1.58e-182	-	-	-	S	-	-	-	Alpha beta hydrolase
CKHKLAEA_00655	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CKHKLAEA_00656	4.75e-132	-	-	-	-	-	-	-	-
CKHKLAEA_00658	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CKHKLAEA_00659	8.37e-29	-	-	-	-	-	-	-	-
CKHKLAEA_00662	1.1e-95	-	-	-	-	-	-	-	-
CKHKLAEA_00663	8.62e-225	-	-	-	-	-	-	-	-
CKHKLAEA_00664	3.04e-235	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
CKHKLAEA_00665	4.82e-180	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CKHKLAEA_00666	4.18e-165	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKHKLAEA_00667	2.96e-100	-	-	-	S	-	-	-	Flavodoxin
CKHKLAEA_00668	3.25e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
CKHKLAEA_00669	4.04e-48	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
CKHKLAEA_00670	5.25e-279	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
CKHKLAEA_00671	3.9e-212	-	-	-	H	-	-	-	geranyltranstransferase activity
CKHKLAEA_00672	9.46e-235	-	-	-	-	-	-	-	-
CKHKLAEA_00673	3.11e-26	-	-	-	-	-	-	-	-
CKHKLAEA_00674	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
CKHKLAEA_00675	9.18e-243	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
CKHKLAEA_00676	1.56e-60	-	-	-	-	-	-	-	-
CKHKLAEA_00677	2.03e-136	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CKHKLAEA_00678	9.66e-110	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
CKHKLAEA_00679	2.19e-291	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
CKHKLAEA_00680	4.94e-109	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
CKHKLAEA_00681	2.33e-239	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
CKHKLAEA_00682	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CKHKLAEA_00683	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
CKHKLAEA_00684	7.3e-131	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
CKHKLAEA_00685	1.91e-167	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
CKHKLAEA_00686	9.68e-250	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CKHKLAEA_00687	7.66e-196	-	-	-	EG	-	-	-	EamA-like transporter family
CKHKLAEA_00688	1.15e-152	-	-	-	L	-	-	-	Integrase
CKHKLAEA_00689	7.24e-204	rssA	-	-	S	-	-	-	Phospholipase, patatin family
CKHKLAEA_00690	1.93e-39	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
CKHKLAEA_00691	9.77e-71	-	-	-	-	-	-	-	-
CKHKLAEA_00693	2.85e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
CKHKLAEA_00696	1.2e-100	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
CKHKLAEA_00697	2.23e-20	-	-	-	-	-	-	-	-
CKHKLAEA_00701	4.83e-28	-	-	-	-	-	-	-	-
CKHKLAEA_00702	7.03e-81	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
CKHKLAEA_00707	6.91e-58	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
CKHKLAEA_00708	6.19e-173	-	-	-	S	-	-	-	Pfam:Terminase_3C
CKHKLAEA_00709	6.7e-164	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
CKHKLAEA_00710	7.84e-112	-	-	-	S	-	-	-	Phage minor capsid protein 2
CKHKLAEA_00712	1.66e-27	-	-	-	S	-	-	-	Phage minor structural protein GP20
CKHKLAEA_00713	1.33e-122	-	-	-	-	-	-	-	-
CKHKLAEA_00715	6.51e-40	-	-	-	S	-	-	-	Minor capsid protein
CKHKLAEA_00717	5.61e-13	-	-	-	S	-	-	-	Minor capsid protein from bacteriophage
CKHKLAEA_00718	1.69e-48	-	-	-	N	-	-	-	domain, Protein
CKHKLAEA_00720	4.05e-36	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
CKHKLAEA_00721	5.71e-123	-	-	-	M	-	-	-	NlpC/P60 family
CKHKLAEA_00723	1.54e-68	-	-	-	M	-	-	-	Prophage endopeptidase tail
CKHKLAEA_00725	9.62e-111	-	-	-	S	-	-	-	Glycosyltransferase like family
CKHKLAEA_00726	1.29e-105	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
CKHKLAEA_00727	5.19e-49	-	-	-	M	-	-	-	biosynthesis protein
CKHKLAEA_00728	3.94e-122	cps3F	-	-	-	-	-	-	-
CKHKLAEA_00729	3.68e-123	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CKHKLAEA_00730	1.23e-145	-	-	-	S	-	-	-	Glycosyltransferase like family 2
CKHKLAEA_00731	8.61e-94	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
CKHKLAEA_00732	4.63e-270	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
CKHKLAEA_00733	6.1e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
CKHKLAEA_00734	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
CKHKLAEA_00735	4.46e-46	-	-	-	-	-	-	-	-
CKHKLAEA_00736	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
CKHKLAEA_00737	2.33e-202	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CKHKLAEA_00738	2.23e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CKHKLAEA_00739	9.64e-141	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CKHKLAEA_00740	1.35e-206	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CKHKLAEA_00741	2.15e-46	-	-	-	S	-	-	-	Domain of unknown function DUF1829
CKHKLAEA_00742	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CKHKLAEA_00743	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
CKHKLAEA_00744	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CKHKLAEA_00745	1.86e-208	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CKHKLAEA_00746	1.55e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CKHKLAEA_00747	6.33e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CKHKLAEA_00748	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CKHKLAEA_00749	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CKHKLAEA_00750	6.71e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
CKHKLAEA_00751	4.71e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
CKHKLAEA_00752	2.3e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
CKHKLAEA_00753	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
CKHKLAEA_00754	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CKHKLAEA_00755	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CKHKLAEA_00756	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CKHKLAEA_00757	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CKHKLAEA_00758	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CKHKLAEA_00759	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CKHKLAEA_00760	1.05e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
CKHKLAEA_00761	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
CKHKLAEA_00762	1.05e-308	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CKHKLAEA_00763	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
CKHKLAEA_00764	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
CKHKLAEA_00765	3.86e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
CKHKLAEA_00766	1.17e-61	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
CKHKLAEA_00767	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
CKHKLAEA_00768	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CKHKLAEA_00769	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CKHKLAEA_00770	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_00772	6.17e-286	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CKHKLAEA_00773	3.42e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
CKHKLAEA_00774	2.76e-217	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
CKHKLAEA_00775	9.89e-207	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
CKHKLAEA_00776	1.54e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
CKHKLAEA_00777	3.73e-200	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CKHKLAEA_00778	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
CKHKLAEA_00779	4.83e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CKHKLAEA_00780	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
CKHKLAEA_00781	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CKHKLAEA_00782	7.35e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
CKHKLAEA_00783	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CKHKLAEA_00784	1.09e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CKHKLAEA_00785	1.58e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
CKHKLAEA_00786	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
CKHKLAEA_00787	1.32e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
CKHKLAEA_00788	8.13e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CKHKLAEA_00789	3.27e-159	vanR	-	-	K	-	-	-	response regulator
CKHKLAEA_00790	1.1e-260	hpk31	-	-	T	-	-	-	Histidine kinase
CKHKLAEA_00791	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CKHKLAEA_00793	3.25e-18	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
CKHKLAEA_00794	7.96e-97	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
CKHKLAEA_00795	8.53e-95	-	-	-	-	-	-	-	-
CKHKLAEA_00796	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CKHKLAEA_00797	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
CKHKLAEA_00798	0.0	-	-	-	M	-	-	-	domain protein
CKHKLAEA_00799	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CKHKLAEA_00800	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CKHKLAEA_00801	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CKHKLAEA_00802	4.03e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CKHKLAEA_00803	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CKHKLAEA_00804	7.72e-232	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
CKHKLAEA_00805	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CKHKLAEA_00807	8.9e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
CKHKLAEA_00808	2.02e-272	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
CKHKLAEA_00809	3.98e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CKHKLAEA_00810	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CKHKLAEA_00811	1.13e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
CKHKLAEA_00812	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CKHKLAEA_00813	2.06e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
CKHKLAEA_00814	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
CKHKLAEA_00815	2.13e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
CKHKLAEA_00816	4.04e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
CKHKLAEA_00817	2.06e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_00818	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CKHKLAEA_00819	1.62e-118	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
CKHKLAEA_00820	4.46e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
CKHKLAEA_00821	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
CKHKLAEA_00822	6.98e-156	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
CKHKLAEA_00823	2.13e-312	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
CKHKLAEA_00824	1.22e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CKHKLAEA_00825	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CKHKLAEA_00826	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CKHKLAEA_00827	6.92e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
CKHKLAEA_00828	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
CKHKLAEA_00829	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
CKHKLAEA_00830	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CKHKLAEA_00831	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
CKHKLAEA_00832	4.32e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
CKHKLAEA_00833	1.22e-93	-	-	-	-	-	-	-	-
CKHKLAEA_00834	5.05e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
CKHKLAEA_00835	3.15e-153	dltr	-	-	K	-	-	-	response regulator
CKHKLAEA_00836	1.13e-289	sptS	-	-	T	-	-	-	Histidine kinase
CKHKLAEA_00837	1.41e-265	-	-	-	P	-	-	-	Voltage gated chloride channel
CKHKLAEA_00838	2.89e-161	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
CKHKLAEA_00839	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
CKHKLAEA_00840	2.1e-214	-	-	-	C	-	-	-	Aldo keto reductase
CKHKLAEA_00841	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
CKHKLAEA_00842	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
CKHKLAEA_00843	7.6e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
CKHKLAEA_00844	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
CKHKLAEA_00845	6.39e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CKHKLAEA_00846	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CKHKLAEA_00849	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CKHKLAEA_00850	5.28e-225	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CKHKLAEA_00851	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
CKHKLAEA_00852	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
CKHKLAEA_00853	5.11e-188	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CKHKLAEA_00854	4.32e-155	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
CKHKLAEA_00857	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CKHKLAEA_00858	9.61e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
CKHKLAEA_00859	2.57e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
CKHKLAEA_00860	2.6e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CKHKLAEA_00861	9.02e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
CKHKLAEA_00862	4.26e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CKHKLAEA_00863	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
CKHKLAEA_00864	4.02e-286	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
CKHKLAEA_00865	2.82e-133	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
CKHKLAEA_00866	4.51e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CKHKLAEA_00867	9.85e-59	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
CKHKLAEA_00868	1.06e-50	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CKHKLAEA_00869	5.66e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CKHKLAEA_00870	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CKHKLAEA_00871	8.99e-109	-	-	-	-	-	-	-	-
CKHKLAEA_00872	8.83e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
CKHKLAEA_00873	3.67e-71	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
CKHKLAEA_00874	3.67e-46	-	-	-	-	-	-	-	-
CKHKLAEA_00875	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CKHKLAEA_00876	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
CKHKLAEA_00877	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
CKHKLAEA_00878	5.33e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CKHKLAEA_00879	2.54e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
CKHKLAEA_00880	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
CKHKLAEA_00881	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CKHKLAEA_00882	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CKHKLAEA_00883	4.94e-285	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CKHKLAEA_00884	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
CKHKLAEA_00885	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CKHKLAEA_00886	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CKHKLAEA_00887	4.72e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CKHKLAEA_00888	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CKHKLAEA_00889	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
CKHKLAEA_00890	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CKHKLAEA_00891	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
CKHKLAEA_00892	1.91e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
CKHKLAEA_00893	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
CKHKLAEA_00894	9.22e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CKHKLAEA_00895	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
CKHKLAEA_00896	2.47e-167	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
CKHKLAEA_00897	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CKHKLAEA_00898	8.26e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CKHKLAEA_00899	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CKHKLAEA_00900	4.44e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CKHKLAEA_00901	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CKHKLAEA_00902	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CKHKLAEA_00903	9e-72	-	-	-	-	-	-	-	-
CKHKLAEA_00904	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
CKHKLAEA_00905	3.2e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CKHKLAEA_00906	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
CKHKLAEA_00907	6.95e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CKHKLAEA_00908	4.02e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CKHKLAEA_00909	1.09e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CKHKLAEA_00910	1.61e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CKHKLAEA_00911	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKHKLAEA_00912	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
CKHKLAEA_00913	1.22e-147	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
CKHKLAEA_00914	2.13e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CKHKLAEA_00915	3.84e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CKHKLAEA_00916	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
CKHKLAEA_00917	1.77e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
CKHKLAEA_00918	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
CKHKLAEA_00919	1.34e-144	-	-	-	K	-	-	-	Transcriptional regulator
CKHKLAEA_00923	4.21e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
CKHKLAEA_00924	7.6e-226	-	-	-	-	-	-	-	-
CKHKLAEA_00925	4.87e-203	-	-	-	-	-	-	-	-
CKHKLAEA_00926	1.54e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
CKHKLAEA_00927	1.99e-131	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CKHKLAEA_00928	1.14e-195	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CKHKLAEA_00929	1.28e-18	-	-	-	-	-	-	-	-
CKHKLAEA_00930	4.08e-157	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CKHKLAEA_00931	4.85e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CKHKLAEA_00932	1.36e-198	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKHKLAEA_00933	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CKHKLAEA_00934	3.39e-186	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKHKLAEA_00935	2.41e-189	-	-	-	E	-	-	-	Glyoxalase-like domain
CKHKLAEA_00936	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
CKHKLAEA_00937	1.1e-125	-	-	-	S	-	-	-	reductase
CKHKLAEA_00939	6.2e-114	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CKHKLAEA_00940	6.05e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CKHKLAEA_00941	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
CKHKLAEA_00942	2.25e-283	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
CKHKLAEA_00943	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
CKHKLAEA_00944	5.87e-192	yycI	-	-	S	-	-	-	YycH protein
CKHKLAEA_00945	2.41e-315	yycH	-	-	S	-	-	-	YycH protein
CKHKLAEA_00946	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CKHKLAEA_00947	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
CKHKLAEA_00949	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
CKHKLAEA_00950	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
CKHKLAEA_00952	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
CKHKLAEA_00953	4.87e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
CKHKLAEA_00954	1.97e-297	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
CKHKLAEA_00955	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
CKHKLAEA_00956	1.77e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CKHKLAEA_00957	1.25e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
CKHKLAEA_00958	1.11e-237	ampC	-	-	V	-	-	-	Beta-lactamase
CKHKLAEA_00959	2.01e-76	-	-	-	-	-	-	-	-
CKHKLAEA_00960	0.0	-	-	-	M	-	-	-	domain protein
CKHKLAEA_00961	3.42e-135	-	-	-	-	-	-	-	-
CKHKLAEA_00963	8.9e-200	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CKHKLAEA_00964	8.67e-89	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CKHKLAEA_00966	2.13e-74	-	-	-	-	-	-	-	-
CKHKLAEA_00968	1.23e-110	-	-	-	-	-	-	-	-
CKHKLAEA_00969	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
CKHKLAEA_00970	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
CKHKLAEA_00971	1.6e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
CKHKLAEA_00972	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
CKHKLAEA_00973	1.29e-205	-	-	-	EG	-	-	-	EamA-like transporter family
CKHKLAEA_00974	1.45e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
CKHKLAEA_00975	2.33e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
CKHKLAEA_00976	6.51e-194	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CKHKLAEA_00977	5.82e-194	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
CKHKLAEA_00978	7.41e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CKHKLAEA_00979	1.43e-160	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
CKHKLAEA_00980	2.47e-192	-	-	-	-	-	-	-	-
CKHKLAEA_00981	1.55e-309	-	-	-	M	-	-	-	Glycosyl transferase
CKHKLAEA_00982	1.29e-279	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
CKHKLAEA_00983	7.72e-179	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
CKHKLAEA_00984	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
CKHKLAEA_00985	3.91e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
CKHKLAEA_00986	2.8e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
CKHKLAEA_00987	2.66e-114	-	-	-	Q	-	-	-	Methyltransferase
CKHKLAEA_00988	2.11e-290	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CKHKLAEA_00989	2.72e-82	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
CKHKLAEA_00990	1.89e-19	-	-	-	G	ko:K03832	-	ko00000,ko02000	Belongs to the glycosyl hydrolase family 6
CKHKLAEA_00991	1.18e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
CKHKLAEA_00992	7.47e-174	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CKHKLAEA_00993	1.02e-216	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
CKHKLAEA_01001	1.74e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CKHKLAEA_01002	1.34e-311	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
CKHKLAEA_01003	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
CKHKLAEA_01004	3.94e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CKHKLAEA_01005	3.48e-192	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
CKHKLAEA_01006	2.73e-148	-	-	-	M	-	-	-	LysM domain protein
CKHKLAEA_01007	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
CKHKLAEA_01008	4.57e-137	-	-	-	M	-	-	-	LysM domain protein
CKHKLAEA_01009	3.31e-189	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
CKHKLAEA_01010	3.3e-211	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
CKHKLAEA_01011	5.38e-308	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
CKHKLAEA_01012	7.77e-198	yeaE	-	-	S	-	-	-	Aldo keto
CKHKLAEA_01013	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CKHKLAEA_01014	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
CKHKLAEA_01015	3.77e-102	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CKHKLAEA_01016	5.03e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
CKHKLAEA_01017	7.03e-33	-	-	-	-	-	-	-	-
CKHKLAEA_01018	8.28e-135	-	-	-	V	-	-	-	VanZ like family
CKHKLAEA_01021	2.71e-54	-	-	-	O	-	-	-	Bacterial dnaA protein
CKHKLAEA_01022	1.25e-99	-	-	-	O	-	-	-	Bacterial dnaA protein
CKHKLAEA_01023	1.51e-300	-	-	-	L	-	-	-	Integrase core domain
CKHKLAEA_01024	2.03e-307	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
CKHKLAEA_01025	3.5e-167	-	-	-	IQ	-	-	-	dehydrogenase reductase
CKHKLAEA_01026	3.88e-50	-	-	-	-	-	-	-	-
CKHKLAEA_01027	1.63e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
CKHKLAEA_01028	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
CKHKLAEA_01029	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
CKHKLAEA_01030	3.97e-232	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CKHKLAEA_01032	2.9e-57	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
CKHKLAEA_01033	7.3e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
CKHKLAEA_01034	1.01e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CKHKLAEA_01036	4.45e-226	ydhF	-	-	S	-	-	-	Aldo keto reductase
CKHKLAEA_01037	3.18e-101	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
CKHKLAEA_01038	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
CKHKLAEA_01040	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
CKHKLAEA_01041	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
CKHKLAEA_01042	5.98e-14	-	-	-	-	-	-	-	-
CKHKLAEA_01043	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
CKHKLAEA_01044	3.96e-61	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
CKHKLAEA_01045	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CKHKLAEA_01046	1.69e-235	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
CKHKLAEA_01047	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CKHKLAEA_01048	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CKHKLAEA_01049	9.59e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CKHKLAEA_01050	1.91e-261	camS	-	-	S	-	-	-	sex pheromone
CKHKLAEA_01051	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CKHKLAEA_01052	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
CKHKLAEA_01053	8.91e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CKHKLAEA_01054	3.91e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CKHKLAEA_01055	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
CKHKLAEA_01056	4.46e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
CKHKLAEA_01057	9.03e-229	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
CKHKLAEA_01058	6.25e-246	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKHKLAEA_01059	3.39e-124	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
CKHKLAEA_01060	2.64e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CKHKLAEA_01061	2.24e-101	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CKHKLAEA_01062	1.43e-143	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
CKHKLAEA_01063	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
CKHKLAEA_01064	3.07e-265	-	-	-	G	-	-	-	Transporter, major facilitator family protein
CKHKLAEA_01065	1.18e-140	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
CKHKLAEA_01066	9.54e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
CKHKLAEA_01067	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CKHKLAEA_01068	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CKHKLAEA_01069	5.19e-27	-	-	-	-	-	-	-	-
CKHKLAEA_01070	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
CKHKLAEA_01071	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
CKHKLAEA_01072	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
CKHKLAEA_01073	1.59e-303	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
CKHKLAEA_01074	7.28e-75	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CKHKLAEA_01075	1.96e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
CKHKLAEA_01076	5.02e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
CKHKLAEA_01077	2.12e-253	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CKHKLAEA_01078	5.14e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKHKLAEA_01079	6.3e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CKHKLAEA_01080	4.25e-176	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CKHKLAEA_01081	1.82e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
CKHKLAEA_01082	6.98e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CKHKLAEA_01083	1.39e-231	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKHKLAEA_01084	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
CKHKLAEA_01085	1.34e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CKHKLAEA_01087	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CKHKLAEA_01088	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CKHKLAEA_01089	3.11e-106	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
CKHKLAEA_01090	0.0	-	-	-	E	-	-	-	amino acid
CKHKLAEA_01091	0.0	ydaO	-	-	E	-	-	-	amino acid
CKHKLAEA_01092	2.63e-53	-	-	-	-	-	-	-	-
CKHKLAEA_01093	2.7e-258	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
CKHKLAEA_01094	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CKHKLAEA_01095	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
CKHKLAEA_01096	8.18e-174	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
CKHKLAEA_01097	4.16e-180	-	-	-	S	-	-	-	Membrane
CKHKLAEA_01098	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
CKHKLAEA_01099	9.79e-29	-	-	-	-	-	-	-	-
CKHKLAEA_01100	2.03e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CKHKLAEA_01101	1.88e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
CKHKLAEA_01102	3.61e-61	-	-	-	-	-	-	-	-
CKHKLAEA_01103	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
CKHKLAEA_01104	8.8e-264	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
CKHKLAEA_01105	3.44e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
CKHKLAEA_01106	3.47e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
CKHKLAEA_01107	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
CKHKLAEA_01108	1.91e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
CKHKLAEA_01109	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
CKHKLAEA_01110	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CKHKLAEA_01111	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CKHKLAEA_01112	2.06e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CKHKLAEA_01113	4.92e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKHKLAEA_01114	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CKHKLAEA_01115	1.96e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CKHKLAEA_01116	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CKHKLAEA_01117	3.53e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
CKHKLAEA_01118	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
CKHKLAEA_01119	1.01e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_01120	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CKHKLAEA_01121	1.77e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
CKHKLAEA_01122	3.87e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
CKHKLAEA_01123	1.83e-197	-	-	-	GM	-	-	-	NAD(P)H-binding
CKHKLAEA_01124	4.44e-11	-	-	-	-	-	-	-	-
CKHKLAEA_01125	5.23e-276	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
CKHKLAEA_01126	0.0	cadA	-	-	P	-	-	-	P-type ATPase
CKHKLAEA_01127	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
CKHKLAEA_01128	6.02e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
CKHKLAEA_01129	1.87e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CKHKLAEA_01130	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CKHKLAEA_01131	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CKHKLAEA_01132	6.09e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
CKHKLAEA_01133	3.7e-199	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CKHKLAEA_01134	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
CKHKLAEA_01135	1.29e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CKHKLAEA_01136	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
CKHKLAEA_01137	2.14e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CKHKLAEA_01138	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
CKHKLAEA_01139	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CKHKLAEA_01140	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CKHKLAEA_01141	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CKHKLAEA_01142	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CKHKLAEA_01143	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
CKHKLAEA_01144	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKHKLAEA_01145	4.63e-255	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKHKLAEA_01146	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
CKHKLAEA_01147	3.1e-168	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
CKHKLAEA_01148	8.01e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
CKHKLAEA_01149	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
CKHKLAEA_01150	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CKHKLAEA_01152	2.78e-293	-	-	-	L	-	-	-	Integrase core domain
CKHKLAEA_01153	4.31e-180	-	-	-	L	-	-	-	Bacterial dnaA protein
CKHKLAEA_01154	2.77e-51	-	-	-	-	-	-	-	-
CKHKLAEA_01155	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CKHKLAEA_01156	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CKHKLAEA_01157	1.79e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CKHKLAEA_01158	1.69e-306	-	-	-	M	-	-	-	Glycosyl transferase family group 2
CKHKLAEA_01160	1.86e-288	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
CKHKLAEA_01161	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CKHKLAEA_01162	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CKHKLAEA_01163	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
CKHKLAEA_01164	2.9e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CKHKLAEA_01165	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CKHKLAEA_01166	1.05e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKHKLAEA_01167	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CKHKLAEA_01168	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CKHKLAEA_01169	5.12e-266	yacL	-	-	S	-	-	-	domain protein
CKHKLAEA_01170	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CKHKLAEA_01171	1.1e-125	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
CKHKLAEA_01172	3.33e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
CKHKLAEA_01173	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CKHKLAEA_01174	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CKHKLAEA_01175	3.51e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
CKHKLAEA_01176	2.38e-171	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_01177	9.62e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CKHKLAEA_01178	2.47e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
CKHKLAEA_01179	6.27e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CKHKLAEA_01180	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CKHKLAEA_01181	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
CKHKLAEA_01182	5.27e-235	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
CKHKLAEA_01183	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
CKHKLAEA_01185	4.73e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
CKHKLAEA_01186	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
CKHKLAEA_01187	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CKHKLAEA_01188	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CKHKLAEA_01189	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
CKHKLAEA_01190	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
CKHKLAEA_01191	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
CKHKLAEA_01192	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CKHKLAEA_01193	1.55e-143	-	-	-	-	-	-	-	-
CKHKLAEA_01196	1.85e-202	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CKHKLAEA_01197	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
CKHKLAEA_01200	9.11e-114	-	-	-	C	-	-	-	Oxidoreductase
CKHKLAEA_01201	3.41e-27	-	-	-	C	-	-	-	Oxidoreductase
CKHKLAEA_01202	2.89e-68	-	-	-	C	-	-	-	Oxidoreductase
CKHKLAEA_01203	3.88e-71	-	-	-	S	-	-	-	macrophage migration inhibitory factor
CKHKLAEA_01204	4.95e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
CKHKLAEA_01205	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CKHKLAEA_01207	3.01e-285	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
CKHKLAEA_01208	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
CKHKLAEA_01212	1.21e-247	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CKHKLAEA_01213	1.92e-284	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CKHKLAEA_01214	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CKHKLAEA_01215	5.21e-198	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
CKHKLAEA_01216	1.12e-272	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
CKHKLAEA_01217	3.45e-246	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
CKHKLAEA_01218	3.34e-189	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
CKHKLAEA_01219	3.77e-245	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
CKHKLAEA_01222	1.12e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
CKHKLAEA_01223	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKHKLAEA_01224	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CKHKLAEA_01225	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
CKHKLAEA_01226	5.18e-222	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
CKHKLAEA_01227	4.25e-271	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
CKHKLAEA_01228	4.95e-191	-	-	-	L	-	-	-	PFAM Integrase catalytic region
CKHKLAEA_01229	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
CKHKLAEA_01230	1.44e-208	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
CKHKLAEA_01231	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
CKHKLAEA_01232	4.94e-35	-	-	-	S	-	-	-	Acyltransferase family
CKHKLAEA_01234	8.1e-281	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CKHKLAEA_01235	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKHKLAEA_01236	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CKHKLAEA_01237	7.13e-227	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CKHKLAEA_01238	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
CKHKLAEA_01239	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
CKHKLAEA_01240	8.4e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
CKHKLAEA_01241	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
CKHKLAEA_01242	1.38e-59	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
CKHKLAEA_01243	1.43e-16	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
CKHKLAEA_01244	9.34e-130	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CKHKLAEA_01245	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CKHKLAEA_01246	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CKHKLAEA_01247	0.0	-	-	-	S	-	-	-	membrane
CKHKLAEA_01248	1.33e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
CKHKLAEA_01249	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
CKHKLAEA_01250	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CKHKLAEA_01251	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
CKHKLAEA_01252	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CKHKLAEA_01253	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CKHKLAEA_01254	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CKHKLAEA_01255	8.8e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CKHKLAEA_01256	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CKHKLAEA_01257	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CKHKLAEA_01258	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
CKHKLAEA_01259	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CKHKLAEA_01260	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CKHKLAEA_01261	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CKHKLAEA_01262	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CKHKLAEA_01263	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CKHKLAEA_01264	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CKHKLAEA_01265	1.06e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CKHKLAEA_01266	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CKHKLAEA_01267	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CKHKLAEA_01268	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
CKHKLAEA_01269	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CKHKLAEA_01270	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CKHKLAEA_01271	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CKHKLAEA_01272	9.82e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CKHKLAEA_01273	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
CKHKLAEA_01274	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CKHKLAEA_01275	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CKHKLAEA_01276	8.91e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CKHKLAEA_01277	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
CKHKLAEA_01278	2.61e-105	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
CKHKLAEA_01279	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
CKHKLAEA_01280	9.71e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
CKHKLAEA_01281	3.86e-205	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
CKHKLAEA_01282	8.34e-147	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
CKHKLAEA_01283	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
CKHKLAEA_01284	1.11e-201	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
CKHKLAEA_01285	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
CKHKLAEA_01286	1.54e-191	-	-	-	O	-	-	-	Band 7 protein
CKHKLAEA_01287	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
CKHKLAEA_01288	8.31e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
CKHKLAEA_01289	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
CKHKLAEA_01290	4.38e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
CKHKLAEA_01291	2.78e-205	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CKHKLAEA_01292	2.84e-136	-	-	-	L	-	-	-	Helix-turn-helix domain
CKHKLAEA_01293	2.49e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
CKHKLAEA_01294	9.14e-66	-	-	-	-	-	-	-	-
CKHKLAEA_01296	4.42e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
CKHKLAEA_01297	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CKHKLAEA_01298	3.09e-35	-	-	-	-	-	-	-	-
CKHKLAEA_01299	2.3e-124	-	-	-	-	-	-	-	-
CKHKLAEA_01300	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
CKHKLAEA_01301	3.99e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
CKHKLAEA_01302	5.18e-15	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
CKHKLAEA_01303	8.11e-137	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
CKHKLAEA_01304	4.92e-82	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
CKHKLAEA_01305	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
CKHKLAEA_01306	5.91e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CKHKLAEA_01307	1.09e-62	-	-	-	-	-	-	-	-
CKHKLAEA_01308	1.81e-41	-	-	-	-	-	-	-	-
CKHKLAEA_01309	1.26e-60	-	-	-	-	-	-	-	-
CKHKLAEA_01310	6.49e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
CKHKLAEA_01311	1.01e-15	-	-	-	-	-	-	-	-
CKHKLAEA_01312	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
CKHKLAEA_01313	2.63e-264	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CKHKLAEA_01314	3.58e-224	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CKHKLAEA_01315	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
CKHKLAEA_01316	0.0	snf	-	-	KL	-	-	-	domain protein
CKHKLAEA_01318	7.01e-41	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
CKHKLAEA_01319	3.57e-12	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
CKHKLAEA_01321	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
CKHKLAEA_01322	3.8e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CKHKLAEA_01323	1.09e-250	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CKHKLAEA_01324	8.56e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CKHKLAEA_01325	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CKHKLAEA_01326	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
CKHKLAEA_01327	1.38e-37	-	-	-	-	-	-	-	-
CKHKLAEA_01328	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
CKHKLAEA_01329	7.43e-129	-	-	-	S	-	-	-	Pfam:DUF3816
CKHKLAEA_01330	1.35e-182	-	-	-	G	-	-	-	MucBP domain
CKHKLAEA_01331	2.26e-145	-	-	-	-	-	-	-	-
CKHKLAEA_01332	9.47e-202	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_01333	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
CKHKLAEA_01334	1.44e-124	epsB	-	-	M	-	-	-	biosynthesis protein
CKHKLAEA_01335	3.01e-140	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
CKHKLAEA_01336	4.29e-13	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
CKHKLAEA_01337	1.12e-43	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
CKHKLAEA_01338	1.38e-102	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
CKHKLAEA_01339	1.66e-81	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
CKHKLAEA_01340	2.03e-50	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
CKHKLAEA_01342	1.42e-85	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CKHKLAEA_01343	1.11e-32	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
CKHKLAEA_01344	4.77e-36	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
CKHKLAEA_01345	8.23e-32	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
CKHKLAEA_01346	2.41e-57	-	-	-	S	-	-	-	Glycosyltransferase like family 2
CKHKLAEA_01347	4.74e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
CKHKLAEA_01348	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKHKLAEA_01349	5.3e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
CKHKLAEA_01350	6.03e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CKHKLAEA_01351	9.83e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CKHKLAEA_01352	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
CKHKLAEA_01353	5.5e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CKHKLAEA_01354	1.66e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CKHKLAEA_01355	2.31e-156	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CKHKLAEA_01356	4.12e-164	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
CKHKLAEA_01357	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
CKHKLAEA_01358	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CKHKLAEA_01359	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CKHKLAEA_01360	2.27e-100	-	-	-	-	-	-	-	-
CKHKLAEA_01361	1.89e-189	yidA	-	-	S	-	-	-	hydrolase
CKHKLAEA_01362	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
CKHKLAEA_01363	4.82e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
CKHKLAEA_01364	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
CKHKLAEA_01365	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CKHKLAEA_01366	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CKHKLAEA_01367	5.29e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CKHKLAEA_01368	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
CKHKLAEA_01369	3.58e-300	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CKHKLAEA_01370	1.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CKHKLAEA_01371	4.29e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
CKHKLAEA_01372	6.11e-289	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CKHKLAEA_01373	6.08e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CKHKLAEA_01374	6.21e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
CKHKLAEA_01375	1.51e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
CKHKLAEA_01376	2.71e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKHKLAEA_01377	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
CKHKLAEA_01378	1.06e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
CKHKLAEA_01379	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CKHKLAEA_01380	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CKHKLAEA_01381	2.29e-158	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
CKHKLAEA_01382	1.96e-239	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
CKHKLAEA_01383	4.83e-212	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
CKHKLAEA_01384	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CKHKLAEA_01385	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CKHKLAEA_01386	1.23e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
CKHKLAEA_01387	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CKHKLAEA_01388	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
CKHKLAEA_01389	1.88e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CKHKLAEA_01390	1.54e-269	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CKHKLAEA_01391	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
CKHKLAEA_01392	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
CKHKLAEA_01393	2.75e-309	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
CKHKLAEA_01394	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
CKHKLAEA_01395	2.7e-145	-	-	-	S	-	-	-	(CBS) domain
CKHKLAEA_01396	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CKHKLAEA_01397	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CKHKLAEA_01398	1.18e-51	yabO	-	-	J	-	-	-	S4 domain protein
CKHKLAEA_01399	7.15e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
CKHKLAEA_01400	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
CKHKLAEA_01401	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CKHKLAEA_01402	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
CKHKLAEA_01403	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKHKLAEA_01404	7.93e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CKHKLAEA_01405	1.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CKHKLAEA_01406	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
CKHKLAEA_01407	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
CKHKLAEA_01414	7.89e-168	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
CKHKLAEA_01415	1.55e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
CKHKLAEA_01416	2.41e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CKHKLAEA_01417	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
CKHKLAEA_01418	4.61e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CKHKLAEA_01419	6.2e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CKHKLAEA_01420	4.93e-286	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CKHKLAEA_01421	1.22e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
CKHKLAEA_01422	1.38e-203	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
CKHKLAEA_01423	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CKHKLAEA_01424	1.33e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKHKLAEA_01425	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
CKHKLAEA_01426	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CKHKLAEA_01428	3.82e-255	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CKHKLAEA_01429	3.97e-184	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKHKLAEA_01430	3.5e-166	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKHKLAEA_01431	8.97e-207	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CKHKLAEA_01432	6.22e-175	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CKHKLAEA_01433	1.84e-201	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
CKHKLAEA_01434	5.65e-275	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
CKHKLAEA_01435	8.8e-241	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
CKHKLAEA_01436	2.1e-276	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
CKHKLAEA_01437	5.07e-56	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
CKHKLAEA_01438	6.12e-194	is18	-	-	L	-	-	-	Integrase core domain
CKHKLAEA_01439	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CKHKLAEA_01440	2.18e-79	-	-	-	-	-	-	-	-
CKHKLAEA_01441	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CKHKLAEA_01442	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
CKHKLAEA_01443	2.72e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
CKHKLAEA_01444	1.3e-227	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CKHKLAEA_01445	4.22e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_01446	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_01447	9.55e-21	-	-	-	-	-	-	-	-
CKHKLAEA_01448	0.0	-	-	-	L	-	-	-	PLD-like domain
CKHKLAEA_01449	2.5e-47	higA	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
CKHKLAEA_01450	8.75e-183	yeeC	-	-	P	-	-	-	T5orf172
CKHKLAEA_01451	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
CKHKLAEA_01452	5.16e-105	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
CKHKLAEA_01454	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
CKHKLAEA_01455	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
CKHKLAEA_01456	4.3e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
CKHKLAEA_01457	2.46e-113	-	-	-	-	-	-	-	-
CKHKLAEA_01458	6.55e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
CKHKLAEA_01459	2.03e-272	yttB	-	-	EGP	-	-	-	Major Facilitator
CKHKLAEA_01460	1.03e-146	-	-	-	-	-	-	-	-
CKHKLAEA_01461	2.14e-32	-	-	-	-	-	-	-	-
CKHKLAEA_01462	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
CKHKLAEA_01463	7.15e-315	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CKHKLAEA_01465	5.65e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
CKHKLAEA_01466	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
CKHKLAEA_01467	7.62e-268	-	-	-	P	-	-	-	Chloride transporter, ClC family
CKHKLAEA_01468	5.25e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CKHKLAEA_01469	8.69e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CKHKLAEA_01470	9.06e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CKHKLAEA_01471	1.19e-65	-	-	-	-	-	-	-	-
CKHKLAEA_01472	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
CKHKLAEA_01473	4.65e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
CKHKLAEA_01474	1.36e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
CKHKLAEA_01475	1.2e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
CKHKLAEA_01476	6.99e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CKHKLAEA_01477	1.01e-28	-	-	-	-	-	-	-	-
CKHKLAEA_01478	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
CKHKLAEA_01479	4.68e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
CKHKLAEA_01480	2.54e-60	yrvD	-	-	S	-	-	-	Pfam:DUF1049
CKHKLAEA_01482	1.47e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
CKHKLAEA_01483	2.6e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CKHKLAEA_01484	7.05e-101	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CKHKLAEA_01485	3.55e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
CKHKLAEA_01486	6.14e-71	-	-	-	-	-	-	-	-
CKHKLAEA_01487	4.87e-238	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
CKHKLAEA_01488	4.93e-35	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
CKHKLAEA_01489	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CKHKLAEA_01490	2.37e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKHKLAEA_01491	2.48e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CKHKLAEA_01492	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CKHKLAEA_01493	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CKHKLAEA_01494	3.26e-48	-	-	-	-	-	-	-	-
CKHKLAEA_01495	3.91e-130	-	-	-	K	-	-	-	DNA-templated transcription, initiation
CKHKLAEA_01496	3.34e-38	-	-	-	-	-	-	-	-
CKHKLAEA_01497	4.04e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
CKHKLAEA_01498	6.27e-293	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
CKHKLAEA_01499	6.74e-53	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CKHKLAEA_01500	5.08e-219	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CKHKLAEA_01501	1.16e-185	epsB	-	-	M	-	-	-	biosynthesis protein
CKHKLAEA_01502	3.79e-155	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
CKHKLAEA_01503	8.05e-65	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
CKHKLAEA_01504	1.13e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CKHKLAEA_01505	7.22e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CKHKLAEA_01506	7.45e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
CKHKLAEA_01507	1.4e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
CKHKLAEA_01508	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CKHKLAEA_01509	2.41e-264	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
CKHKLAEA_01510	2.7e-155	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CKHKLAEA_01511	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CKHKLAEA_01512	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
CKHKLAEA_01513	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CKHKLAEA_01514	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CKHKLAEA_01515	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CKHKLAEA_01516	1.97e-153	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
CKHKLAEA_01517	1.15e-263	-	-	-	-	-	-	-	-
CKHKLAEA_01518	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CKHKLAEA_01519	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CKHKLAEA_01520	1.72e-142	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CKHKLAEA_01521	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CKHKLAEA_01522	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
CKHKLAEA_01523	8.94e-250	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
CKHKLAEA_01524	4.62e-21	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
CKHKLAEA_01525	4.09e-116	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
CKHKLAEA_01531	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
CKHKLAEA_01532	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
CKHKLAEA_01534	2.79e-153	-	-	-	I	-	-	-	phosphatase
CKHKLAEA_01535	2.05e-104	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
CKHKLAEA_01536	2.09e-166	-	-	-	S	-	-	-	Putative threonine/serine exporter
CKHKLAEA_01537	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CKHKLAEA_01538	9.44e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
CKHKLAEA_01539	2.85e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
CKHKLAEA_01540	7.33e-152	-	-	-	S	-	-	-	membrane
CKHKLAEA_01541	2.34e-142	-	-	-	S	-	-	-	VIT family
CKHKLAEA_01542	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
CKHKLAEA_01543	8.01e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_01544	4.49e-194	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CKHKLAEA_01545	1.06e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CKHKLAEA_01546	2.11e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CKHKLAEA_01547	8.69e-277	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CKHKLAEA_01548	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CKHKLAEA_01549	4.03e-75	-	-	-	-	-	-	-	-
CKHKLAEA_01550	1.47e-95	-	-	-	K	-	-	-	MerR HTH family regulatory protein
CKHKLAEA_01551	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
CKHKLAEA_01552	9.49e-154	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
CKHKLAEA_01553	2.24e-205	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CKHKLAEA_01555	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CKHKLAEA_01556	5.59e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
CKHKLAEA_01557	7.85e-241	-	-	-	I	-	-	-	Alpha beta
CKHKLAEA_01558	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
CKHKLAEA_01559	2.22e-151	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
CKHKLAEA_01560	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
CKHKLAEA_01561	7.21e-205	-	-	-	K	-	-	-	LysR family
CKHKLAEA_01562	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
CKHKLAEA_01563	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
CKHKLAEA_01564	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CKHKLAEA_01565	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
CKHKLAEA_01566	5.46e-207	mleR	-	-	K	-	-	-	LysR family
CKHKLAEA_01567	2.87e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CKHKLAEA_01568	1.35e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
CKHKLAEA_01569	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
CKHKLAEA_01570	1.23e-212	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
CKHKLAEA_01571	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
CKHKLAEA_01572	1.36e-35	-	-	-	-	-	-	-	-
CKHKLAEA_01573	3.67e-255	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
CKHKLAEA_01574	5.36e-97	-	-	-	-	-	-	-	-
CKHKLAEA_01575	9.29e-290	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CKHKLAEA_01576	3.66e-183	-	-	-	V	-	-	-	Beta-lactamase enzyme family
CKHKLAEA_01577	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
CKHKLAEA_01578	3.66e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
CKHKLAEA_01579	0.0	arcT	-	-	E	-	-	-	Dipeptidase
CKHKLAEA_01580	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
CKHKLAEA_01581	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
CKHKLAEA_01582	5.38e-225	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKHKLAEA_01583	6.83e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CKHKLAEA_01584	2.49e-43	-	-	-	-	-	-	-	-
CKHKLAEA_01585	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
CKHKLAEA_01586	7.17e-240	-	-	-	M	-	-	-	hydrolase, family 25
CKHKLAEA_01587	3.92e-74	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
CKHKLAEA_01588	9.11e-45	-	-	-	-	-	-	-	-
CKHKLAEA_01592	8.66e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
CKHKLAEA_01594	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CKHKLAEA_01595	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
CKHKLAEA_01596	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
CKHKLAEA_01597	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CKHKLAEA_01598	1.58e-106	-	-	-	-	-	-	-	-
CKHKLAEA_01599	2.31e-278	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
CKHKLAEA_01600	1.41e-53	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
CKHKLAEA_01601	5.71e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CKHKLAEA_01602	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
CKHKLAEA_01603	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CKHKLAEA_01608	6.11e-26	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
CKHKLAEA_01610	1.24e-201	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CKHKLAEA_01611	2.69e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CKHKLAEA_01612	1.98e-83	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
CKHKLAEA_01613	1.2e-144	-	-	-	S	-	-	-	Membrane
CKHKLAEA_01614	6.22e-56	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
CKHKLAEA_01615	8.28e-20	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKHKLAEA_01616	1.89e-36	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKHKLAEA_01617	8.6e-215	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
CKHKLAEA_01618	2.26e-46	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
CKHKLAEA_01620	1.39e-82	repB	-	-	L	-	-	-	Initiator Replication protein
CKHKLAEA_01621	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
CKHKLAEA_01622	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CKHKLAEA_01623	6.12e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CKHKLAEA_01624	1.43e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CKHKLAEA_01625	9.73e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CKHKLAEA_01626	1.23e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CKHKLAEA_01627	7e-206	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
CKHKLAEA_01628	1.92e-143	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
CKHKLAEA_01635	2.34e-16	-	-	-	-	-	-	-	-
CKHKLAEA_01636	3.46e-39	-	-	-	K	-	-	-	Helix-turn-helix domain
CKHKLAEA_01637	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKHKLAEA_01638	1.4e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
CKHKLAEA_01639	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
CKHKLAEA_01641	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CKHKLAEA_01642	6.47e-285	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
CKHKLAEA_01643	1.68e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
CKHKLAEA_01644	6.98e-122	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
CKHKLAEA_01645	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
CKHKLAEA_01646	6.28e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CKHKLAEA_01647	1.3e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CKHKLAEA_01648	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CKHKLAEA_01649	2.37e-184	-	-	-	S	-	-	-	DUF218 domain
CKHKLAEA_01650	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
CKHKLAEA_01651	5.51e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
CKHKLAEA_01652	1.97e-97	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
CKHKLAEA_01653	2.9e-309	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
CKHKLAEA_01654	9.49e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
CKHKLAEA_01655	6.14e-104	-	-	-	S	-	-	-	Cupin domain
CKHKLAEA_01656	6.21e-91	-	-	-	C	-	-	-	Flavodoxin
CKHKLAEA_01657	5.9e-48	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
CKHKLAEA_01658	2.99e-218	yvgN	-	-	C	-	-	-	Aldo keto reductase
CKHKLAEA_01659	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
CKHKLAEA_01660	1.66e-305	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
CKHKLAEA_01661	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CKHKLAEA_01662	3.46e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
CKHKLAEA_01663	1.03e-202	gspA	-	-	M	-	-	-	family 8
CKHKLAEA_01664	2.2e-292	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
CKHKLAEA_01665	7.28e-101	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
CKHKLAEA_01666	9.78e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CKHKLAEA_01667	2.05e-121	-	-	-	-	-	-	-	-
CKHKLAEA_01668	2.95e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
CKHKLAEA_01669	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
CKHKLAEA_01670	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CKHKLAEA_01671	9.15e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
CKHKLAEA_01672	5.61e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CKHKLAEA_01673	1.92e-91	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CKHKLAEA_01674	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
CKHKLAEA_01675	2.2e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
CKHKLAEA_01676	3.43e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
CKHKLAEA_01677	1.01e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
CKHKLAEA_01678	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CKHKLAEA_01679	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
CKHKLAEA_01680	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CKHKLAEA_01681	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
CKHKLAEA_01682	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
CKHKLAEA_01683	1.75e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
CKHKLAEA_01684	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
CKHKLAEA_01685	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
CKHKLAEA_01686	6.02e-219	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
CKHKLAEA_01687	1.71e-217	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
CKHKLAEA_01688	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
CKHKLAEA_01689	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CKHKLAEA_01690	5.52e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
CKHKLAEA_01691	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
CKHKLAEA_01692	2.43e-241	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
CKHKLAEA_01693	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
CKHKLAEA_01695	6.94e-315	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
CKHKLAEA_01696	2.71e-153	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
CKHKLAEA_01697	7.36e-28	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
CKHKLAEA_01699	1.08e-89	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
CKHKLAEA_01700	1.3e-50	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
CKHKLAEA_01701	5.66e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
CKHKLAEA_01702	7.15e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
CKHKLAEA_01703	1.26e-243	flp	-	-	V	-	-	-	Beta-lactamase
CKHKLAEA_01704	8e-145	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
CKHKLAEA_01705	1.01e-120	dpsB	-	-	P	-	-	-	Belongs to the Dps family
CKHKLAEA_01706	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
CKHKLAEA_01707	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
CKHKLAEA_01709	2.1e-50	-	-	-	K	-	-	-	Helix-turn-helix domain
CKHKLAEA_01710	2.2e-70	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
CKHKLAEA_01711	6.38e-122	-	-	-	L	-	-	-	Integrase
CKHKLAEA_01712	6.88e-49	-	-	-	-	-	-	-	-
CKHKLAEA_01715	1.21e-51	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
CKHKLAEA_01716	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
CKHKLAEA_01717	4.51e-54	-	-	-	S	-	-	-	Cytochrome B5
CKHKLAEA_01718	4.77e-270	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
CKHKLAEA_01720	1.63e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKHKLAEA_01721	2.39e-301	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CKHKLAEA_01722	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CKHKLAEA_01723	0.0	-	-	-	J	-	-	-	Elongation factor G, domain IV
CKHKLAEA_01724	1.63e-281	-	-	-	-	-	-	-	-
CKHKLAEA_01725	3.3e-203	-	-	-	J	-	-	-	Methyltransferase
CKHKLAEA_01726	2.1e-288	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
CKHKLAEA_01727	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
CKHKLAEA_01728	1.44e-137	pduB	-	-	E	-	-	-	BMC
CKHKLAEA_01729	5.07e-47	-	-	-	CQ	-	-	-	BMC
CKHKLAEA_01730	6.91e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CKHKLAEA_01731	6.45e-49	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
CKHKLAEA_01732	1.22e-197	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
CKHKLAEA_01733	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
CKHKLAEA_01734	5.1e-121	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
CKHKLAEA_01735	7.1e-226	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CKHKLAEA_01736	2.6e-234	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
CKHKLAEA_01737	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CKHKLAEA_01738	1.8e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
CKHKLAEA_01739	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CKHKLAEA_01740	2.14e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
CKHKLAEA_01741	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
CKHKLAEA_01742	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
CKHKLAEA_01743	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CKHKLAEA_01744	2e-263	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CKHKLAEA_01745	1.69e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CKHKLAEA_01746	2.2e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
CKHKLAEA_01747	1.85e-201	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CKHKLAEA_01748	1.58e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
CKHKLAEA_01749	1.11e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
CKHKLAEA_01750	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
CKHKLAEA_01751	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
CKHKLAEA_01752	1.08e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
CKHKLAEA_01753	9.56e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
CKHKLAEA_01754	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CKHKLAEA_01755	1.95e-177	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CKHKLAEA_01756	1.35e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CKHKLAEA_01757	1.67e-163	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CKHKLAEA_01758	1.08e-132	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CKHKLAEA_01759	7.6e-246	-	-	-	S	-	-	-	Helix-turn-helix domain
CKHKLAEA_01760	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CKHKLAEA_01761	2.15e-83	-	-	-	M	-	-	-	Lysin motif
CKHKLAEA_01762	3.8e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
CKHKLAEA_01763	1e-272	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
CKHKLAEA_01764	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
CKHKLAEA_01765	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CKHKLAEA_01766	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
CKHKLAEA_01767	2.86e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CKHKLAEA_01768	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_01769	5.13e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CKHKLAEA_01770	3.38e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CKHKLAEA_01771	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
CKHKLAEA_01772	5.24e-195	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
CKHKLAEA_01773	4.79e-221	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
CKHKLAEA_01774	4.05e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
CKHKLAEA_01775	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
CKHKLAEA_01776	1.99e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CKHKLAEA_01777	2.05e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CKHKLAEA_01778	7.84e-207	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
CKHKLAEA_01779	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CKHKLAEA_01780	7.89e-212	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
CKHKLAEA_01781	1.9e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CKHKLAEA_01782	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CKHKLAEA_01783	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CKHKLAEA_01784	2.41e-111	-	-	-	F	-	-	-	NUDIX domain
CKHKLAEA_01785	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
CKHKLAEA_01786	1.34e-104	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
CKHKLAEA_01788	1.17e-27	-	3.1.21.5	-	KL	ko:K01156	-	ko00000,ko01000,ko02048	type III restriction enzyme, res subunit
CKHKLAEA_01789	7.62e-19	-	-	-	K	-	-	-	Helix-turn-helix domain
CKHKLAEA_01790	9.97e-18	-	-	-	-	-	-	-	-
CKHKLAEA_01791	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CKHKLAEA_01792	3.43e-273	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
CKHKLAEA_01793	1.76e-258	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
CKHKLAEA_01794	8.89e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
CKHKLAEA_01795	1.95e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CKHKLAEA_01796	3.81e-88	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
CKHKLAEA_01798	9.19e-233	yueF	-	-	S	-	-	-	AI-2E family transporter
CKHKLAEA_01799	4.58e-169	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
CKHKLAEA_01803	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
CKHKLAEA_01804	1.51e-207	-	-	-	-	-	-	-	-
CKHKLAEA_01805	1.92e-202	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
CKHKLAEA_01806	1.32e-236	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
CKHKLAEA_01807	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
CKHKLAEA_01808	1.36e-101	yybA	-	-	K	-	-	-	Transcriptional regulator
CKHKLAEA_01809	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
CKHKLAEA_01810	3.16e-114	-	-	-	GM	-	-	-	epimerase
CKHKLAEA_01811	1.39e-198	-	-	-	V	-	-	-	(ABC) transporter
CKHKLAEA_01812	4.79e-307	yhdP	-	-	S	-	-	-	Transporter associated domain
CKHKLAEA_01813	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
CKHKLAEA_01814	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
CKHKLAEA_01815	2.17e-245	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
CKHKLAEA_01816	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CKHKLAEA_01817	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CKHKLAEA_01818	1.06e-53	-	-	-	-	-	-	-	-
CKHKLAEA_01819	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
CKHKLAEA_01820	1.61e-50	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
CKHKLAEA_01821	2.65e-13	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
CKHKLAEA_01822	2.32e-104	usp5	-	-	T	-	-	-	universal stress protein
CKHKLAEA_01823	1.39e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
CKHKLAEA_01824	3.7e-297	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CKHKLAEA_01825	2.56e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
CKHKLAEA_01826	1.97e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CKHKLAEA_01827	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
CKHKLAEA_01828	8.5e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CKHKLAEA_01829	1.34e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
CKHKLAEA_01830	5.69e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CKHKLAEA_01831	5.55e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
CKHKLAEA_01832	1.21e-48	-	-	-	-	-	-	-	-
CKHKLAEA_01833	2.51e-68	-	-	-	-	-	-	-	-
CKHKLAEA_01834	2.24e-261	-	-	-	-	-	-	-	-
CKHKLAEA_01835	1.36e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CKHKLAEA_01836	9.74e-176	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
CKHKLAEA_01837	7.23e-202	yvgN	-	-	S	-	-	-	Aldo keto reductase
CKHKLAEA_01838	2.22e-171	XK27_10500	-	-	K	-	-	-	response regulator
CKHKLAEA_01839	2.4e-230	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
CKHKLAEA_01840	4.29e-175	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_01841	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CKHKLAEA_01842	9.9e-202	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
CKHKLAEA_01843	3.74e-213	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
CKHKLAEA_01844	1.39e-69	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CKHKLAEA_01845	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKHKLAEA_01846	7.33e-253	-	-	-	EGP	-	-	-	Major Facilitator
CKHKLAEA_01847	2.18e-115	ymdB	-	-	S	-	-	-	Macro domain protein
CKHKLAEA_01848	2.13e-142	-	-	-	K	-	-	-	Helix-turn-helix domain
CKHKLAEA_01849	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
CKHKLAEA_01850	1.66e-61	-	-	-	-	-	-	-	-
CKHKLAEA_01851	1.32e-307	-	-	-	S	-	-	-	Putative metallopeptidase domain
CKHKLAEA_01852	1.46e-261	-	-	-	S	-	-	-	associated with various cellular activities
CKHKLAEA_01853	1.92e-153	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
CKHKLAEA_01854	2.01e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
CKHKLAEA_01856	7.94e-150	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
CKHKLAEA_01857	2.84e-73	-	-	-	-	-	-	-	-
CKHKLAEA_01859	1.97e-131	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
CKHKLAEA_01860	1.62e-34	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
CKHKLAEA_01861	5.87e-65	-	-	-	-	-	-	-	-
CKHKLAEA_01862	5.28e-262	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
CKHKLAEA_01863	6.07e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
CKHKLAEA_01864	1.8e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CKHKLAEA_01865	5.99e-137	-	-	-	NU	-	-	-	mannosyl-glycoprotein
CKHKLAEA_01866	8.04e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
CKHKLAEA_01867	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
CKHKLAEA_01868	5.56e-25	-	-	-	-	-	-	-	-
CKHKLAEA_01869	1.28e-65	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
CKHKLAEA_01870	1.18e-56	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CKHKLAEA_01871	6.38e-122	-	-	-	L	-	-	-	Integrase
CKHKLAEA_01878	4.95e-195	-	-	-	E	-	-	-	AzlC protein
CKHKLAEA_01879	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
CKHKLAEA_01880	2.05e-15	-	-	-	-	-	-	-	-
CKHKLAEA_01881	5.23e-184	-	-	-	S	-	-	-	Phage major capsid protein E
CKHKLAEA_01882	1.4e-47	-	-	-	-	-	-	-	-
CKHKLAEA_01885	9.23e-65	-	-	-	-	-	-	-	-
CKHKLAEA_01904	8.94e-122	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
CKHKLAEA_01905	7.09e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CKHKLAEA_01906	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
CKHKLAEA_01907	6.92e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
CKHKLAEA_01908	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CKHKLAEA_01909	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CKHKLAEA_01910	2.36e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CKHKLAEA_01911	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CKHKLAEA_01912	2.22e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKHKLAEA_01913	1.79e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
CKHKLAEA_01914	3.89e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CKHKLAEA_01915	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
CKHKLAEA_01916	7.99e-293	-	-	-	V	-	-	-	MatE
CKHKLAEA_01917	0.0	potE	-	-	E	-	-	-	Amino Acid
CKHKLAEA_01918	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CKHKLAEA_01919	1.38e-155	csrR	-	-	K	-	-	-	response regulator
CKHKLAEA_01920	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
CKHKLAEA_01921	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
CKHKLAEA_01922	9.69e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
CKHKLAEA_01923	3.16e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
CKHKLAEA_01924	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CKHKLAEA_01925	3.6e-146	yqeK	-	-	H	-	-	-	Hydrolase, HD family
CKHKLAEA_01926	2.83e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CKHKLAEA_01927	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
CKHKLAEA_01928	5.44e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
CKHKLAEA_01929	3.17e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
CKHKLAEA_01930	2.23e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CKHKLAEA_01931	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
CKHKLAEA_01932	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CKHKLAEA_01933	9.62e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
CKHKLAEA_01934	7.76e-274	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
CKHKLAEA_01935	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CKHKLAEA_01936	5.91e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CKHKLAEA_01937	2.74e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CKHKLAEA_01938	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CKHKLAEA_01939	5.63e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
CKHKLAEA_01940	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
CKHKLAEA_01941	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
CKHKLAEA_01942	9.47e-48	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
CKHKLAEA_01943	7.39e-64	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
CKHKLAEA_01944	1.63e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CKHKLAEA_01945	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
CKHKLAEA_01946	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
CKHKLAEA_01947	2.46e-122	-	-	-	J	-	-	-	Aminoglycoside-2''-adenylyltransferase
CKHKLAEA_01948	5.22e-255	-	-	-	L	-	-	-	transposition, DNA-mediated
CKHKLAEA_01949	2.26e-25	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
CKHKLAEA_01950	4.17e-92	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
CKHKLAEA_01951	2.32e-233	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
CKHKLAEA_01952	5.88e-126	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CKHKLAEA_01953	9.64e-183	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CKHKLAEA_01954	7.98e-311	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
CKHKLAEA_01955	7.51e-77	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
CKHKLAEA_01956	3.31e-37	-	-	-	S	-	-	-	YSIRK type signal peptide
CKHKLAEA_01957	1.85e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CKHKLAEA_01958	6.64e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CKHKLAEA_01959	4.47e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CKHKLAEA_01960	4.99e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
CKHKLAEA_01962	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CKHKLAEA_01963	0.0	yhaN	-	-	L	-	-	-	AAA domain
CKHKLAEA_01964	2.62e-282	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
CKHKLAEA_01965	3.75e-77	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
CKHKLAEA_01966	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
CKHKLAEA_01967	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase