ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GPBMILCE_00001 0.0 - - - O - - - Arylsulfotransferase (ASST)
GPBMILCE_00002 1.67e-229 - - - S - - - Conserved hypothetical protein 698
GPBMILCE_00003 1.15e-84 - - - S - - - NADPH-dependent FMN reductase
GPBMILCE_00022 4.46e-46 - - - - - - - -
GPBMILCE_00023 1.95e-184 - - - G - - - Peptidase_C39 like family
GPBMILCE_00024 1.41e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
GPBMILCE_00025 3.63e-292 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GPBMILCE_00026 5.9e-48 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
GPBMILCE_00027 5.28e-29 - - - - - - - -
GPBMILCE_00028 1.21e-20 - - - - - - - -
GPBMILCE_00029 2.26e-129 - - - K - - - DNA-templated transcription, initiation
GPBMILCE_00030 3.26e-48 - - - - - - - -
GPBMILCE_00031 4.66e-231 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
GPBMILCE_00032 1.49e-285 - - - L ko:K07484 - ko00000 Transposase IS66 family
GPBMILCE_00034 2.09e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GPBMILCE_00035 4.95e-86 - - - K - - - HxlR-like helix-turn-helix
GPBMILCE_00036 3.88e-71 - - - S - - - macrophage migration inhibitory factor
GPBMILCE_00037 2.89e-68 - - - C - - - Oxidoreductase
GPBMILCE_00038 3.41e-27 - - - C - - - Oxidoreductase
GPBMILCE_00039 2.12e-112 - - - C - - - Oxidoreductase
GPBMILCE_00042 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
GPBMILCE_00043 1.85e-202 - - - S - - - Calcineurin-like phosphoesterase
GPBMILCE_00046 1.55e-143 - - - - - - - -
GPBMILCE_00047 0.0 - - - EGP - - - Major Facilitator
GPBMILCE_00048 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
GPBMILCE_00049 1.1e-171 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GPBMILCE_00050 1.44e-164 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
GPBMILCE_00051 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPBMILCE_00052 6.42e-198 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GPBMILCE_00053 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
GPBMILCE_00054 5.75e-112 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GPBMILCE_00056 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
GPBMILCE_00057 3.18e-236 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
GPBMILCE_00058 0.0 - - - S - - - Bacterial membrane protein, YfhO
GPBMILCE_00059 3.04e-172 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPBMILCE_00060 6.27e-216 - - - I - - - alpha/beta hydrolase fold
GPBMILCE_00061 2.47e-273 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GPBMILCE_00062 9.62e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GPBMILCE_00063 2.38e-171 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_00064 3.51e-180 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
GPBMILCE_00065 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GPBMILCE_00066 2.5e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPBMILCE_00067 3.33e-66 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
GPBMILCE_00068 1.1e-125 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
GPBMILCE_00069 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPBMILCE_00070 5.12e-266 yacL - - S - - - domain protein
GPBMILCE_00071 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GPBMILCE_00072 3.58e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GPBMILCE_00073 1.05e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPBMILCE_00074 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GPBMILCE_00075 2.9e-31 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GPBMILCE_00076 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GPBMILCE_00077 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPBMILCE_00078 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GPBMILCE_00079 1.86e-288 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
GPBMILCE_00081 1.9e-313 - - - M - - - Glycosyl transferase family group 2
GPBMILCE_00082 2.5e-246 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GPBMILCE_00083 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPBMILCE_00084 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GPBMILCE_00086 3.46e-92 - - - - - - - -
GPBMILCE_00087 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
GPBMILCE_00088 5.21e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
GPBMILCE_00090 2.17e-56 - - - S - - - Membrane
GPBMILCE_00091 6.36e-75 - - - - - - - -
GPBMILCE_00092 5.95e-238 - - - L - - - PFAM Integrase catalytic region
GPBMILCE_00093 2.33e-41 - - - M - - - Lysin motif
GPBMILCE_00094 5.04e-132 - - - L - - - Transposase
GPBMILCE_00095 1.86e-62 - - - S - - - PD-(D/E)XK nuclease family transposase
GPBMILCE_00096 9.45e-152 - - - S - - - HAD hydrolase, family IA, variant
GPBMILCE_00097 0.0 yagE - - E - - - amino acid
GPBMILCE_00098 4.16e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GPBMILCE_00099 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GPBMILCE_00100 8.65e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GPBMILCE_00101 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GPBMILCE_00102 5.08e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GPBMILCE_00103 2.49e-187 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GPBMILCE_00104 5.39e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GPBMILCE_00105 6.98e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GPBMILCE_00106 1.97e-293 - - - - - - - -
GPBMILCE_00107 1.77e-298 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
GPBMILCE_00108 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
GPBMILCE_00109 3.59e-97 - - - F - - - Nudix hydrolase
GPBMILCE_00110 2.75e-132 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
GPBMILCE_00111 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
GPBMILCE_00112 6.02e-34 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
GPBMILCE_00113 2.69e-192 - - - - - - - -
GPBMILCE_00114 8.65e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
GPBMILCE_00115 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
GPBMILCE_00116 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
GPBMILCE_00117 1.29e-232 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPBMILCE_00118 6.08e-13 - - - S - - - CsbD-like
GPBMILCE_00119 1.34e-47 - - - S - - - Transglycosylase associated protein
GPBMILCE_00120 1.27e-291 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPBMILCE_00121 9.5e-162 pgm3 - - G - - - phosphoglycerate mutase
GPBMILCE_00122 2.31e-148 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
GPBMILCE_00123 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GPBMILCE_00124 1.26e-44 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
GPBMILCE_00125 1.77e-202 - - - EG - - - EamA-like transporter family
GPBMILCE_00126 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GPBMILCE_00127 3.39e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GPBMILCE_00128 7.02e-288 - - - S ko:K07133 - ko00000 cog cog1373
GPBMILCE_00130 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GPBMILCE_00132 1.25e-192 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GPBMILCE_00133 6.89e-27 ydcL - - L - - - Belongs to the 'phage' integrase family
GPBMILCE_00134 4.1e-103 - - - L ko:K07482 - ko00000 transposase and inactivated derivatives, IS30 family
GPBMILCE_00135 3.41e-152 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPBMILCE_00136 7.96e-97 - - - K - - - Transcriptional regulator, TetR family
GPBMILCE_00143 9.76e-58 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
GPBMILCE_00144 6.74e-35 - - - S ko:K07088 - ko00000 Membrane transport protein
GPBMILCE_00145 2.34e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
GPBMILCE_00146 8.25e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GPBMILCE_00147 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GPBMILCE_00148 6.06e-168 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_00149 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GPBMILCE_00150 4.94e-210 - - - G - - - Phosphotransferase enzyme family
GPBMILCE_00151 1.88e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GPBMILCE_00152 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPBMILCE_00153 1.96e-71 - - - - - - - -
GPBMILCE_00154 1.66e-165 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GPBMILCE_00155 4.65e-229 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
GPBMILCE_00156 7.92e-76 - - - - - - - -
GPBMILCE_00158 4.78e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GPBMILCE_00160 1.01e-254 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
GPBMILCE_00161 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GPBMILCE_00162 3.58e-34 - - - S - - - Bacteriophage abortive infection AbiH
GPBMILCE_00163 3.5e-251 - - - M - - - hydrolase, family 25
GPBMILCE_00164 1.09e-83 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
GPBMILCE_00165 1.49e-25 - - - - - - - -
GPBMILCE_00168 4.94e-209 - - - M - - - CotH kinase protein
GPBMILCE_00170 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
GPBMILCE_00171 3.58e-202 - - - S - - - Phage tail protein
GPBMILCE_00172 0.0 - - - L - - - Phage tail tape measure protein TP901
GPBMILCE_00173 1.75e-75 - - - - - - - -
GPBMILCE_00174 2.24e-147 - - - - - - - -
GPBMILCE_00175 1.7e-101 - - - - - - - -
GPBMILCE_00176 1.85e-82 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
GPBMILCE_00177 1.34e-55 - - - S - - - Phage head-tail joining protein
GPBMILCE_00178 9.88e-91 - - - S - - - Phage gp6-like head-tail connector protein
GPBMILCE_00179 5.12e-266 - - - S - - - Phage capsid family
GPBMILCE_00180 3.54e-148 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
GPBMILCE_00181 1.12e-307 - - - S - - - Phage portal protein
GPBMILCE_00184 0.0 terL - - S - - - overlaps another CDS with the same product name
GPBMILCE_00185 1.62e-100 - - - L - - - Phage terminase, small subunit
GPBMILCE_00186 2.32e-200 - - - L - - - HNH nucleases
GPBMILCE_00189 1.04e-41 - - - - - - - -
GPBMILCE_00190 0.0 - - - S - - - ABC transporter, ATP-binding protein
GPBMILCE_00191 8.04e-184 - - - S - - - Putative ABC-transporter type IV
GPBMILCE_00192 7.28e-138 - - - NU - - - mannosyl-glycoprotein
GPBMILCE_00193 1.8e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GPBMILCE_00194 6.07e-292 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GPBMILCE_00195 5.28e-262 yngD - - S ko:K07097 - ko00000 DHHA1 domain
GPBMILCE_00197 5.87e-65 - - - - - - - -
GPBMILCE_00198 1.62e-34 - - - S - - - PD-(D/E)XK nuclease family transposase
GPBMILCE_00199 6.51e-130 - - - S - - - PD-(D/E)XK nuclease family transposase
GPBMILCE_00201 2.84e-73 - - - - - - - -
GPBMILCE_00202 6.8e-151 yrkL - - S - - - Flavodoxin-like fold
GPBMILCE_00204 9.94e-85 yeaO - - S - - - Protein of unknown function, DUF488
GPBMILCE_00205 1.92e-153 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GPBMILCE_00206 1.46e-261 - - - S - - - associated with various cellular activities
GPBMILCE_00207 2.66e-307 - - - S - - - Putative metallopeptidase domain
GPBMILCE_00208 4.95e-63 - - - - - - - -
GPBMILCE_00209 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GPBMILCE_00210 2.13e-142 - - - K - - - Helix-turn-helix domain
GPBMILCE_00211 6.26e-115 ymdB - - S - - - Macro domain protein
GPBMILCE_00212 7.33e-253 - - - EGP - - - Major Facilitator
GPBMILCE_00213 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPBMILCE_00214 1.13e-68 - - - K - - - helix_turn_helix, mercury resistance
GPBMILCE_00215 3.74e-213 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GPBMILCE_00216 8.48e-203 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
GPBMILCE_00217 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
GPBMILCE_00218 1.01e-173 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_00219 7.79e-236 kinG - - T - - - Histidine kinase-like ATPases
GPBMILCE_00220 2.82e-163 XK27_10500 - - K - - - response regulator
GPBMILCE_00221 8.44e-201 yvgN - - S - - - Aldo keto reductase
GPBMILCE_00222 9.74e-176 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
GPBMILCE_00223 4.74e-107 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPBMILCE_00224 2.24e-261 - - - - - - - -
GPBMILCE_00225 1.24e-68 - - - - - - - -
GPBMILCE_00226 1.21e-48 - - - - - - - -
GPBMILCE_00227 5.55e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
GPBMILCE_00228 5.69e-189 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GPBMILCE_00229 1.34e-234 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
GPBMILCE_00230 8.5e-287 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPBMILCE_00231 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GPBMILCE_00232 1.97e-231 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GPBMILCE_00233 2.56e-133 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
GPBMILCE_00234 2.14e-296 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPBMILCE_00235 1.39e-106 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
GPBMILCE_00236 7.51e-77 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
GPBMILCE_00237 1.43e-311 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
GPBMILCE_00238 6.79e-183 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GPBMILCE_00239 5.88e-126 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GPBMILCE_00240 1.34e-232 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
GPBMILCE_00241 1.21e-213 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GPBMILCE_00242 3.23e-75 - - - S - - - Small secreted protein
GPBMILCE_00243 2.95e-75 ytpP - - CO - - - Thioredoxin
GPBMILCE_00244 7.77e-151 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPBMILCE_00245 7.39e-64 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
GPBMILCE_00246 8.55e-46 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
GPBMILCE_00247 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GPBMILCE_00248 6.48e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GPBMILCE_00249 3.26e-150 - - - S - - - Protein of unknown function (DUF1275)
GPBMILCE_00250 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPBMILCE_00251 2.74e-204 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GPBMILCE_00252 5.91e-129 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPBMILCE_00253 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPBMILCE_00254 3.31e-275 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
GPBMILCE_00255 9.62e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GPBMILCE_00256 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPBMILCE_00257 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GPBMILCE_00258 2.23e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPBMILCE_00259 3.17e-124 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
GPBMILCE_00260 5.44e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
GPBMILCE_00261 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
GPBMILCE_00262 2.43e-158 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPBMILCE_00263 5.11e-146 yqeK - - H - - - Hydrolase, HD family
GPBMILCE_00264 1.9e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GPBMILCE_00265 1.1e-179 yqeM - - Q - - - Methyltransferase
GPBMILCE_00266 9.69e-274 ylbM - - S - - - Belongs to the UPF0348 family
GPBMILCE_00267 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
GPBMILCE_00268 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GPBMILCE_00269 1.38e-155 csrR - - K - - - response regulator
GPBMILCE_00270 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GPBMILCE_00271 0.0 potE - - E - - - Amino Acid
GPBMILCE_00272 7.99e-293 - - - V - - - MatE
GPBMILCE_00273 9.16e-91 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
GPBMILCE_00274 1.58e-214 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPBMILCE_00275 1.79e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GPBMILCE_00276 2.22e-185 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPBMILCE_00277 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GPBMILCE_00278 2.36e-77 yodB - - K - - - Transcriptional regulator, HxlR family
GPBMILCE_00279 2.12e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPBMILCE_00280 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPBMILCE_00281 6.92e-148 - - - M - - - PFAM NLP P60 protein
GPBMILCE_00282 2.06e-152 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
GPBMILCE_00283 7.09e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPBMILCE_00284 1.83e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
GPBMILCE_00285 2.96e-135 - - - S - - - Protein of unknown function (DUF1461)
GPBMILCE_00286 2.87e-171 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GPBMILCE_00287 9.28e-121 yutD - - S - - - Protein of unknown function (DUF1027)
GPBMILCE_00288 1.08e-146 - - - S - - - Calcineurin-like phosphoesterase
GPBMILCE_00289 4.18e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPBMILCE_00290 2.07e-185 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
GPBMILCE_00292 9.32e-92 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
GPBMILCE_00293 1.61e-54 - - - - - - - -
GPBMILCE_00294 1.01e-100 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
GPBMILCE_00295 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
GPBMILCE_00296 2.49e-232 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GPBMILCE_00297 4.67e-232 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
GPBMILCE_00298 1.22e-168 yebC - - K - - - Transcriptional regulatory protein
GPBMILCE_00299 1.15e-178 - - - - - - - -
GPBMILCE_00300 2.81e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GPBMILCE_00301 8.87e-269 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GPBMILCE_00302 1.84e-75 - - - - - - - -
GPBMILCE_00303 8.88e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GPBMILCE_00304 6.23e-188 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
GPBMILCE_00305 1.1e-195 - - - S - - - haloacid dehalogenase-like hydrolase
GPBMILCE_00306 3.62e-100 ykuL - - S - - - (CBS) domain
GPBMILCE_00307 9.81e-122 - - - S ko:K07095 - ko00000 Phosphoesterase
GPBMILCE_00308 3.33e-133 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPBMILCE_00309 2.58e-184 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GPBMILCE_00310 1.01e-124 yslB - - S - - - Protein of unknown function (DUF2507)
GPBMILCE_00311 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GPBMILCE_00312 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPBMILCE_00313 8.35e-121 cvpA - - S - - - Colicin V production protein
GPBMILCE_00314 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
GPBMILCE_00315 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPBMILCE_00316 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
GPBMILCE_00317 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPBMILCE_00318 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GPBMILCE_00319 6.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
GPBMILCE_00320 7.54e-62 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GPBMILCE_00321 1.25e-241 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GPBMILCE_00322 2.86e-244 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GPBMILCE_00323 1.51e-131 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GPBMILCE_00324 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPBMILCE_00325 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPBMILCE_00326 9.31e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GPBMILCE_00327 6.62e-75 - - - S - - - Uncharacterised protein family (UPF0236)
GPBMILCE_00328 4.05e-70 - - - S - - - branched-chain amino acid
GPBMILCE_00329 4.95e-195 - - - E - - - AzlC protein
GPBMILCE_00330 5.47e-261 hpk31 - - T - - - Histidine kinase
GPBMILCE_00331 3.27e-159 vanR - - K - - - response regulator
GPBMILCE_00332 8.13e-263 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPBMILCE_00333 1.32e-219 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
GPBMILCE_00334 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
GPBMILCE_00335 2.15e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
GPBMILCE_00336 1.09e-296 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPBMILCE_00337 9.74e-154 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPBMILCE_00338 4.25e-173 - - - S - - - Protein of unknown function (DUF1129)
GPBMILCE_00339 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GPBMILCE_00340 5.8e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
GPBMILCE_00341 4.83e-198 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GPBMILCE_00342 2.79e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
GPBMILCE_00343 3.73e-200 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GPBMILCE_00344 6.29e-163 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
GPBMILCE_00345 5.97e-208 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
GPBMILCE_00346 2.76e-217 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
GPBMILCE_00347 3.42e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
GPBMILCE_00348 3.56e-285 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GPBMILCE_00350 5.67e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_00351 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GPBMILCE_00352 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPBMILCE_00353 1.35e-203 - - - L ko:K07497 - ko00000 hmm pf00665
GPBMILCE_00354 3.1e-127 - - - L - - - Helix-turn-helix domain
GPBMILCE_00355 1.08e-05 - - - L - - - Helix-turn-helix domain
GPBMILCE_00356 1.26e-243 flp - - V - - - Beta-lactamase
GPBMILCE_00357 7.15e-122 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GPBMILCE_00358 5.66e-158 - - - S ko:K07507 - ko00000,ko02000 MgtC family
GPBMILCE_00359 1.3e-50 - - - S - - - GyrI-like small molecule binding domain
GPBMILCE_00360 1.08e-89 - - - S - - - GyrI-like small molecule binding domain
GPBMILCE_00362 1.5e-149 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GPBMILCE_00363 4.53e-66 azlD - - E - - - Branched-chain amino acid transport
GPBMILCE_00364 1.01e-42 azlC - - E - - - azaleucine resistance protein AzlC
GPBMILCE_00365 8.59e-98 azlC - - E - - - azaleucine resistance protein AzlC
GPBMILCE_00366 4.47e-74 - - - K - - - Aminotransferase class I and II
GPBMILCE_00367 4.82e-208 - - - K - - - Aminotransferase class I and II
GPBMILCE_00368 0.0 - - - S - - - amidohydrolase
GPBMILCE_00370 1.65e-206 - - - S - - - reductase
GPBMILCE_00371 4.4e-114 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
GPBMILCE_00372 2.44e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GPBMILCE_00373 2.52e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
GPBMILCE_00375 2.87e-43 - - - - - - - -
GPBMILCE_00376 1.56e-51 - - - S - - - Bacteriophage holin
GPBMILCE_00377 4.04e-44 - - - S - - - Haemolysin XhlA
GPBMILCE_00378 1.19e-243 - - - M - - - Glycosyl hydrolases family 25
GPBMILCE_00379 3.02e-72 - - - - - - - -
GPBMILCE_00383 2.53e-130 - - - - - - - -
GPBMILCE_00384 0.0 - - - S - - - Phage minor structural protein
GPBMILCE_00385 0.0 - - - S - - - Phage tail protein
GPBMILCE_00386 0.0 - - - L - - - Phage tail tape measure protein TP901
GPBMILCE_00387 2.6e-33 - - - - - - - -
GPBMILCE_00388 4.04e-77 - - - S - - - Phage tail assembly chaperone proteins, TAC
GPBMILCE_00389 1.28e-135 - - - S - - - Phage tail tube protein
GPBMILCE_00390 1.83e-74 - - - S - - - Protein of unknown function (DUF806)
GPBMILCE_00391 7.25e-83 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
GPBMILCE_00392 3.45e-67 - - - S - - - Phage head-tail joining protein
GPBMILCE_00393 5.64e-66 - - - S - - - Phage gp6-like head-tail connector protein
GPBMILCE_00394 1.27e-272 - - - S - - - Phage capsid family
GPBMILCE_00395 1.6e-163 - - - S - - - Clp protease
GPBMILCE_00396 5.81e-271 - - - S - - - Phage portal protein
GPBMILCE_00397 6.68e-35 - - - S - - - Protein of unknown function (DUF1056)
GPBMILCE_00398 0.0 - - - S - - - Phage Terminase
GPBMILCE_00399 4.86e-102 - - - S - - - Phage terminase, small subunit
GPBMILCE_00400 2e-117 - - - L - - - HNH nucleases
GPBMILCE_00406 2.46e-39 rusA - - L - - - Endodeoxyribonuclease RusA
GPBMILCE_00409 4.05e-142 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
GPBMILCE_00410 7.29e-70 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
GPBMILCE_00411 1.28e-149 - - - S - - - Putative HNHc nuclease
GPBMILCE_00412 6.02e-78 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
GPBMILCE_00426 1.62e-128 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
GPBMILCE_00427 4.92e-305 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPBMILCE_00428 7.38e-232 - - - - - - - -
GPBMILCE_00429 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPBMILCE_00430 4.57e-307 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
GPBMILCE_00431 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
GPBMILCE_00432 8.26e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPBMILCE_00433 5.37e-248 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
GPBMILCE_00434 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPBMILCE_00435 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPBMILCE_00436 1.15e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPBMILCE_00437 2.23e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPBMILCE_00438 2.13e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
GPBMILCE_00439 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPBMILCE_00440 1.61e-271 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPBMILCE_00441 2.11e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPBMILCE_00442 9.77e-170 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
GPBMILCE_00443 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GPBMILCE_00444 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
GPBMILCE_00445 6.76e-227 ydbI - - K - - - AI-2E family transporter
GPBMILCE_00446 1.15e-301 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
GPBMILCE_00447 1.85e-122 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPBMILCE_00448 6.4e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
GPBMILCE_00449 1.83e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPBMILCE_00450 3.95e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GPBMILCE_00451 1.6e-219 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GPBMILCE_00452 3.68e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GPBMILCE_00453 6.04e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GPBMILCE_00454 2.79e-179 - - - K - - - LysR substrate binding domain
GPBMILCE_00455 7.67e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPBMILCE_00456 1.13e-289 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
GPBMILCE_00457 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPBMILCE_00458 2.06e-197 - - - S - - - Helix-turn-helix domain
GPBMILCE_00459 0.0 ymfH - - S - - - Peptidase M16
GPBMILCE_00460 2.13e-294 ymfF - - S - - - Peptidase M16 inactive domain protein
GPBMILCE_00461 4.04e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GPBMILCE_00462 2.06e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_00463 4.45e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GPBMILCE_00464 1.62e-118 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
GPBMILCE_00465 4.46e-194 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GPBMILCE_00466 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
GPBMILCE_00467 6.98e-156 radC - - L ko:K03630 - ko00000 DNA repair protein
GPBMILCE_00468 5.23e-313 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GPBMILCE_00469 1.22e-292 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GPBMILCE_00470 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPBMILCE_00471 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GPBMILCE_00472 6.92e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
GPBMILCE_00473 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
GPBMILCE_00474 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GPBMILCE_00475 5.83e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPBMILCE_00476 2.89e-273 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GPBMILCE_00477 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GPBMILCE_00478 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPBMILCE_00479 5.18e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
GPBMILCE_00480 2.41e-111 - - - F - - - NUDIX domain
GPBMILCE_00481 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPBMILCE_00482 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPBMILCE_00483 1.9e-139 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GPBMILCE_00484 7.89e-212 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GPBMILCE_00485 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPBMILCE_00486 7.84e-207 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GPBMILCE_00487 2.05e-180 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPBMILCE_00488 1.99e-204 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPBMILCE_00489 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
GPBMILCE_00490 8.17e-141 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
GPBMILCE_00491 4.79e-221 - - - E - - - lipolytic protein G-D-S-L family
GPBMILCE_00492 6.38e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
GPBMILCE_00493 2.59e-144 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
GPBMILCE_00494 3.38e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPBMILCE_00495 3.61e-247 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPBMILCE_00496 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_00497 4.94e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GPBMILCE_00498 9.5e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
GPBMILCE_00499 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPBMILCE_00500 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GPBMILCE_00501 1.73e-273 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GPBMILCE_00502 3.8e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GPBMILCE_00503 2.15e-83 - - - M - - - Lysin motif
GPBMILCE_00504 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
GPBMILCE_00505 7.6e-246 - - - S - - - Helix-turn-helix domain
GPBMILCE_00506 2.65e-133 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GPBMILCE_00507 1.67e-163 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GPBMILCE_00508 1.35e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GPBMILCE_00509 1.95e-177 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GPBMILCE_00510 3.67e-86 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPBMILCE_00511 2.35e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
GPBMILCE_00512 1.08e-214 yitL - - S ko:K00243 - ko00000 S1 domain
GPBMILCE_00513 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GPBMILCE_00514 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GPBMILCE_00515 1.11e-41 - - - S - - - Protein of unknown function (DUF2929)
GPBMILCE_00516 9.03e-14 - - - S - - - peptidoglycan catabolic process
GPBMILCE_00517 7.67e-191 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GPBMILCE_00518 5.93e-52 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
GPBMILCE_00525 1.12e-42 - - - LM - - - gp58-like protein
GPBMILCE_00526 6.97e-175 - - - M - - - Prophage endopeptidase tail
GPBMILCE_00527 5.25e-102 - - - S - - - Phage tail protein
GPBMILCE_00528 0.0 - - - L - - - Phage tail tape measure protein TP901
GPBMILCE_00530 1.02e-97 - - - S - - - Phage tail tube protein
GPBMILCE_00532 9.3e-41 - - - S - - - exonuclease activity
GPBMILCE_00534 5.79e-54 - - - S - - - Phage gp6-like head-tail connector protein
GPBMILCE_00535 3.75e-251 - - - S - - - Phage capsid family
GPBMILCE_00536 2.77e-83 - - - S - - - Clp protease
GPBMILCE_00537 6.8e-255 - - - S - - - Phage portal protein
GPBMILCE_00538 0.0 terL - - S - - - overlaps another CDS with the same product name
GPBMILCE_00539 4.79e-82 - - - L - - - Phage terminase, small subunit
GPBMILCE_00540 3.02e-85 - - - L - - - HNH nucleases
GPBMILCE_00542 2.14e-100 - - - - - - - -
GPBMILCE_00544 7.34e-10 - - - S - - - Helix-turn-helix domain
GPBMILCE_00549 7.92e-37 - - - - - - - -
GPBMILCE_00551 4e-156 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
GPBMILCE_00552 2.76e-247 - - - L - - - Belongs to the 'phage' integrase family
GPBMILCE_00553 4.94e-68 - - - S - - - Protein of unknown function (DUF1064)
GPBMILCE_00555 1.03e-44 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
GPBMILCE_00556 4.93e-33 - - - L - - - DnaD domain protein
GPBMILCE_00557 1.78e-14 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
GPBMILCE_00558 6.72e-67 - - - S - - - ERF superfamily
GPBMILCE_00565 3.91e-49 - - - S - - - Protein of unknown function (DUF3102)
GPBMILCE_00567 1.88e-11 - - - - - - - -
GPBMILCE_00568 5.86e-53 - - - K - - - Helix-turn-helix XRE-family like proteins
GPBMILCE_00570 2.74e-26 - - - - - - - -
GPBMILCE_00571 1.46e-116 - - - L - - - Belongs to the 'phage' integrase family
GPBMILCE_00572 1.58e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GPBMILCE_00573 1.85e-201 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPBMILCE_00574 2.2e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GPBMILCE_00575 1.69e-278 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GPBMILCE_00576 1.71e-264 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GPBMILCE_00577 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GPBMILCE_00578 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GPBMILCE_00579 3.05e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GPBMILCE_00580 2.14e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GPBMILCE_00581 1.08e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPBMILCE_00582 7.35e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
GPBMILCE_00583 1.55e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPBMILCE_00584 1.06e-233 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
GPBMILCE_00585 7.1e-226 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GPBMILCE_00586 5.95e-120 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
GPBMILCE_00587 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
GPBMILCE_00588 2.42e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
GPBMILCE_00589 1.2e-234 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GPBMILCE_00590 3.82e-98 - - - L - - - PFAM Integrase catalytic region
GPBMILCE_00591 8.55e-163 - - - O - - - Bacterial dnaA protein
GPBMILCE_00592 3.44e-12 - - - K - - - DNA-binding helix-turn-helix protein
GPBMILCE_00593 6.22e-209 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
GPBMILCE_00594 3.85e-72 - - - - - - - -
GPBMILCE_00595 5.34e-269 yttB - - EGP - - - Major Facilitator
GPBMILCE_00596 6.04e-307 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GPBMILCE_00597 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GPBMILCE_00598 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GPBMILCE_00599 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPBMILCE_00600 5.93e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GPBMILCE_00601 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GPBMILCE_00602 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPBMILCE_00603 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPBMILCE_00604 1.7e-261 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPBMILCE_00605 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
GPBMILCE_00606 9.78e-14 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
GPBMILCE_00607 1.97e-105 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
GPBMILCE_00608 1.41e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GPBMILCE_00609 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPBMILCE_00610 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
GPBMILCE_00611 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GPBMILCE_00612 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPBMILCE_00613 2.55e-169 jag - - S ko:K06346 - ko00000 R3H domain protein
GPBMILCE_00614 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPBMILCE_00615 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GPBMILCE_00616 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GPBMILCE_00617 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPBMILCE_00618 7.33e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
GPBMILCE_00619 2.59e-114 - - - K - - - Acetyltransferase (GNAT) family
GPBMILCE_00620 5.18e-27 - - - - - - - -
GPBMILCE_00621 6.48e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GPBMILCE_00622 2.25e-105 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
GPBMILCE_00623 2.87e-250 - - - S - - - Protein of unknown function (DUF3114)
GPBMILCE_00624 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
GPBMILCE_00625 1.86e-213 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
GPBMILCE_00626 2.95e-135 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GPBMILCE_00627 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
GPBMILCE_00628 5.34e-245 mocA - - S - - - Oxidoreductase
GPBMILCE_00629 8.67e-294 yfmL - - L - - - DEAD DEAH box helicase
GPBMILCE_00631 2.09e-266 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GPBMILCE_00632 2.02e-72 - - - - - - - -
GPBMILCE_00633 4.94e-88 gtcA - - S - - - Teichoic acid glycosylation protein
GPBMILCE_00634 4.7e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
GPBMILCE_00635 1e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
GPBMILCE_00636 3.98e-280 arcT - - E - - - Aminotransferase
GPBMILCE_00637 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
GPBMILCE_00638 0.0 potE - - E - - - Amino Acid
GPBMILCE_00639 7.47e-203 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GPBMILCE_00640 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
GPBMILCE_00641 2.53e-42 - - - - - - - -
GPBMILCE_00642 8.57e-177 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
GPBMILCE_00643 6.4e-188 cps1D - - M - - - Domain of unknown function (DUF4422)
GPBMILCE_00644 3.96e-225 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
GPBMILCE_00645 6.93e-154 - - - M - - - Bacterial sugar transferase
GPBMILCE_00646 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
GPBMILCE_00647 0.0 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
GPBMILCE_00648 1.88e-57 - - - K - - - UTRA
GPBMILCE_00649 1.43e-209 - - - O - - - ADP-ribosylglycohydrolase
GPBMILCE_00650 6.77e-306 - - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
GPBMILCE_00651 2.87e-148 - - - G - - - Belongs to the carbohydrate kinase PfkB family
GPBMILCE_00652 6.05e-159 - - - O - - - Holliday junction DNA helicase ruvB N-terminus
GPBMILCE_00653 5.95e-258 - - - O - - - Subtilase family
GPBMILCE_00654 1.59e-38 - - - - - - - -
GPBMILCE_00657 1.64e-125 - - - V - - - Abi-like protein
GPBMILCE_00659 1.21e-215 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
GPBMILCE_00660 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GPBMILCE_00663 0.0 snf - - KL - - - domain protein
GPBMILCE_00664 2.71e-186 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
GPBMILCE_00665 2.63e-264 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GPBMILCE_00666 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
GPBMILCE_00667 8.58e-223 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPBMILCE_00668 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GPBMILCE_00669 3.82e-157 - - - S - - - repeat protein
GPBMILCE_00670 6.67e-158 pgm6 - - G - - - phosphoglycerate mutase
GPBMILCE_00671 2.15e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GPBMILCE_00672 1.13e-75 XK27_04120 - - S - - - Putative amino acid metabolism
GPBMILCE_00673 1.75e-275 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GPBMILCE_00674 9.75e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPBMILCE_00675 1.54e-33 - - - - - - - -
GPBMILCE_00676 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GPBMILCE_00677 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
GPBMILCE_00678 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPBMILCE_00679 3.71e-109 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
GPBMILCE_00680 1.97e-185 ylmH - - S - - - S4 domain protein
GPBMILCE_00681 3.2e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
GPBMILCE_00682 9.11e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GPBMILCE_00683 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPBMILCE_00684 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GPBMILCE_00685 8.69e-195 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GPBMILCE_00686 1.45e-260 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPBMILCE_00687 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPBMILCE_00688 4.47e-229 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPBMILCE_00689 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GPBMILCE_00690 3.47e-73 ftsL - - D - - - Cell division protein FtsL
GPBMILCE_00691 9.31e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GPBMILCE_00692 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GPBMILCE_00693 7.76e-74 - - - - - - - -
GPBMILCE_00694 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
GPBMILCE_00695 2.4e-160 xylR - - GK - - - ROK family
GPBMILCE_00696 0.0 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
GPBMILCE_00697 3.05e-198 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
GPBMILCE_00698 1.31e-243 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPBMILCE_00699 3.94e-221 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
GPBMILCE_00700 3.18e-206 - - - EG - - - EamA-like transporter family
GPBMILCE_00701 7.03e-134 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
GPBMILCE_00702 1.6e-82 - - - S - - - Cupredoxin-like domain
GPBMILCE_00703 2.2e-65 - - - S - - - Cupredoxin-like domain
GPBMILCE_00704 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GPBMILCE_00705 5.02e-110 - - - - - - - -
GPBMILCE_00707 2.13e-74 - - - - - - - -
GPBMILCE_00709 8.67e-89 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
GPBMILCE_00710 1.09e-200 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
GPBMILCE_00712 3.42e-135 - - - - - - - -
GPBMILCE_00713 0.0 - - - M - - - domain protein
GPBMILCE_00714 3.12e-73 - - - - - - - -
GPBMILCE_00715 9.5e-239 ampC - - V - - - Beta-lactamase
GPBMILCE_00716 1.25e-304 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
GPBMILCE_00717 1.77e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GPBMILCE_00718 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
GPBMILCE_00719 1.97e-297 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
GPBMILCE_00720 4.87e-173 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
GPBMILCE_00721 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
GPBMILCE_00722 5.32e-272 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
GPBMILCE_00723 8.57e-289 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
GPBMILCE_00725 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPBMILCE_00726 2.52e-78 - - - - - - - -
GPBMILCE_00727 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GPBMILCE_00728 7.01e-244 - - - E - - - Zinc-binding dehydrogenase
GPBMILCE_00729 2.72e-113 - - - K - - - transcriptional regulator (TetR family)
GPBMILCE_00730 2.39e-234 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GPBMILCE_00731 4.22e-148 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_00732 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_00733 1.18e-50 - - - - - - - -
GPBMILCE_00734 4.57e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
GPBMILCE_00735 7.15e-315 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPBMILCE_00736 3.11e-220 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
GPBMILCE_00737 2.14e-32 - - - - - - - -
GPBMILCE_00738 1.03e-146 - - - - - - - -
GPBMILCE_00739 4.99e-273 yttB - - EGP - - - Major Facilitator
GPBMILCE_00740 2.66e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GPBMILCE_00741 2.02e-112 - - - - - - - -
GPBMILCE_00742 4.3e-142 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
GPBMILCE_00743 0.0 - - - S - - - Putative peptidoglycan binding domain
GPBMILCE_00744 6.32e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GPBMILCE_00745 1.17e-61 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
GPBMILCE_00746 3.86e-281 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GPBMILCE_00747 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
GPBMILCE_00748 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
GPBMILCE_00749 1.05e-308 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPBMILCE_00750 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
GPBMILCE_00751 1.05e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GPBMILCE_00752 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPBMILCE_00753 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPBMILCE_00754 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPBMILCE_00755 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPBMILCE_00756 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPBMILCE_00757 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPBMILCE_00758 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GPBMILCE_00759 2.3e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
GPBMILCE_00760 2.72e-165 yibF - - S - - - overlaps another CDS with the same product name
GPBMILCE_00761 6.71e-246 yibE - - S - - - overlaps another CDS with the same product name
GPBMILCE_00762 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPBMILCE_00763 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPBMILCE_00764 3.66e-293 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPBMILCE_00765 1.55e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GPBMILCE_00766 1.86e-208 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GPBMILCE_00767 4.95e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPBMILCE_00768 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GPBMILCE_00769 1.04e-299 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GPBMILCE_00770 1.45e-301 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GPBMILCE_00771 1.56e-07 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GPBMILCE_00772 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GPBMILCE_00773 8.18e-174 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
GPBMILCE_00774 4.16e-180 - - - S - - - Membrane
GPBMILCE_00775 5.75e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
GPBMILCE_00776 9.79e-29 - - - - - - - -
GPBMILCE_00777 2.03e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
GPBMILCE_00778 1.55e-308 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
GPBMILCE_00779 3.61e-61 - - - - - - - -
GPBMILCE_00780 1.95e-109 uspA - - T - - - universal stress protein
GPBMILCE_00781 8.8e-264 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
GPBMILCE_00782 2.95e-201 yvgN - - S - - - Aldo keto reductase
GPBMILCE_00783 3.33e-121 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
GPBMILCE_00784 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
GPBMILCE_00785 1.91e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GPBMILCE_00786 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
GPBMILCE_00787 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GPBMILCE_00788 4.3e-111 - - - L - - - Helix-turn-helix domain
GPBMILCE_00789 1.63e-156 - - - L ko:K07497 - ko00000 hmm pf00665
GPBMILCE_00791 4.16e-200 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GPBMILCE_00792 9.38e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GPBMILCE_00793 2.5e-164 - - - O - - - Zinc-dependent metalloprotease
GPBMILCE_00794 6.47e-149 - - - S - - - Membrane
GPBMILCE_00795 6.86e-98 - - - O - - - OsmC-like protein
GPBMILCE_00796 3.24e-226 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPBMILCE_00797 9.71e-274 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GPBMILCE_00798 2.49e-43 - - - - - - - -
GPBMILCE_00799 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
GPBMILCE_00801 1.12e-135 - - - K - - - PFAM GCN5-related N-acetyltransferase
GPBMILCE_00802 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPBMILCE_00803 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GPBMILCE_00804 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GPBMILCE_00805 5.18e-222 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
GPBMILCE_00806 7.36e-272 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GPBMILCE_00807 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GPBMILCE_00808 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
GPBMILCE_00809 4.32e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
GPBMILCE_00810 5.11e-86 - - - - - - - -
GPBMILCE_00811 1.24e-112 - - - T - - - Region found in RelA / SpoT proteins
GPBMILCE_00812 3.68e-152 dltr - - K - - - response regulator
GPBMILCE_00813 7.94e-290 sptS - - T - - - Histidine kinase
GPBMILCE_00814 1.41e-265 - - - P - - - Voltage gated chloride channel
GPBMILCE_00815 2.89e-161 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
GPBMILCE_00816 6.13e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
GPBMILCE_00817 2.1e-214 - - - C - - - Aldo keto reductase
GPBMILCE_00818 1.86e-63 - - - S - - - Cupin 2, conserved barrel domain protein
GPBMILCE_00819 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
GPBMILCE_00820 7.6e-113 - - - S - - - ECF-type riboflavin transporter, S component
GPBMILCE_00821 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
GPBMILCE_00822 6.39e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPBMILCE_00823 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPBMILCE_00824 1.98e-118 - - - - - - - -
GPBMILCE_00825 1.82e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GPBMILCE_00827 6.64e-99 - - - L - - - PFAM Integrase catalytic region
GPBMILCE_00828 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GPBMILCE_00829 1.53e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPBMILCE_00830 7.93e-219 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPBMILCE_00831 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPBMILCE_00832 3.68e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GPBMILCE_00833 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GPBMILCE_00834 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
GPBMILCE_00835 7.15e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GPBMILCE_00836 1.18e-51 yabO - - J - - - S4 domain protein
GPBMILCE_00837 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPBMILCE_00838 7.98e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GPBMILCE_00839 2.7e-145 - - - S - - - (CBS) domain
GPBMILCE_00840 2.06e-188 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
GPBMILCE_00841 1.59e-308 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
GPBMILCE_00842 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
GPBMILCE_00843 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
GPBMILCE_00844 1.54e-269 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPBMILCE_00845 1.88e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GPBMILCE_00846 4.36e-07 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
GPBMILCE_00847 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPBMILCE_00848 1.23e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
GPBMILCE_00849 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPBMILCE_00850 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GPBMILCE_00851 2.4e-212 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GPBMILCE_00852 1.38e-194 - - - D - - - Domain of Unknown Function (DUF1542)
GPBMILCE_00853 1.56e-32 - - - D - - - Domain of Unknown Function (DUF1542)
GPBMILCE_00854 8.02e-159 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
GPBMILCE_00855 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GPBMILCE_00856 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GPBMILCE_00857 1.06e-203 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GPBMILCE_00858 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
GPBMILCE_00859 2.71e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPBMILCE_00860 1.51e-154 - - - G - - - Belongs to the phosphoglycerate mutase family
GPBMILCE_00861 6.21e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
GPBMILCE_00862 6.08e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPBMILCE_00863 1.51e-289 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GPBMILCE_00864 1.75e-161 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
GPBMILCE_00865 1.86e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GPBMILCE_00866 3.07e-301 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPBMILCE_00867 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GPBMILCE_00868 5.29e-300 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPBMILCE_00869 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GPBMILCE_00870 1.04e-85 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GPBMILCE_00871 9.28e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
GPBMILCE_00872 4.82e-188 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
GPBMILCE_00873 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
GPBMILCE_00874 1.89e-189 yidA - - S - - - hydrolase
GPBMILCE_00875 1.6e-100 - - - - - - - -
GPBMILCE_00876 3.53e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPBMILCE_00877 3.17e-314 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPBMILCE_00878 5.24e-191 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GPBMILCE_00879 4.12e-164 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
GPBMILCE_00880 2.31e-156 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GPBMILCE_00881 1.66e-214 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GPBMILCE_00882 9.13e-202 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPBMILCE_00883 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
GPBMILCE_00884 9.83e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GPBMILCE_00885 6.03e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPBMILCE_00886 5.3e-200 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
GPBMILCE_00887 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPBMILCE_00888 1.63e-115 yunF - - F - - - Protein of unknown function DUF72
GPBMILCE_00889 8.49e-68 yunF - - F - - - Protein of unknown function DUF72
GPBMILCE_00891 1.02e-168 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
GPBMILCE_00892 1.09e-227 - - - - - - - -
GPBMILCE_00893 2.08e-283 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
GPBMILCE_00894 4.38e-215 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GPBMILCE_00895 5.54e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GPBMILCE_00896 5.96e-241 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
GPBMILCE_00897 7.04e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
GPBMILCE_00898 0.0 - - - L - - - DNA helicase
GPBMILCE_00899 1.1e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GPBMILCE_00901 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPBMILCE_00902 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
GPBMILCE_00903 4.89e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPBMILCE_00904 1.07e-57 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
GPBMILCE_00905 1.9e-277 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
GPBMILCE_00906 3.43e-85 - - - L - - - Belongs to the 'phage' integrase family
GPBMILCE_00907 2.02e-305 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
GPBMILCE_00908 8.61e-168 - - - IQ - - - dehydrogenase reductase
GPBMILCE_00909 3.88e-50 - - - - - - - -
GPBMILCE_00910 1.63e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
GPBMILCE_00911 2.69e-51 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
GPBMILCE_00912 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GPBMILCE_00913 4.57e-137 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPBMILCE_00914 1.82e-78 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPBMILCE_00916 2.14e-133 - - - S ko:K07002 - ko00000 Serine hydrolase
GPBMILCE_00917 1.26e-82 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
GPBMILCE_00918 8.69e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPBMILCE_00920 9.23e-185 - - - K - - - helix_turn_helix, arabinose operon control protein
GPBMILCE_00921 1.53e-110 - - - S - - - Membrane
GPBMILCE_00922 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
GPBMILCE_00923 5.2e-225 ydhF - - S - - - Aldo keto reductase
GPBMILCE_00924 4.51e-101 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
GPBMILCE_00925 0.0 - - - L - - - Helicase C-terminal domain protein
GPBMILCE_00927 5.71e-315 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
GPBMILCE_00928 2.84e-73 - - - S - - - Sugar efflux transporter for intercellular exchange
GPBMILCE_00929 7.41e-163 - - - - - - - -
GPBMILCE_00931 7.73e-109 - - - S - - - Phage transcriptional regulator, ArpU family
GPBMILCE_00937 5.83e-21 - - - - - - - -
GPBMILCE_00939 8.6e-169 - - - - - - - -
GPBMILCE_00940 6.33e-91 - - - - - - - -
GPBMILCE_00942 1.15e-159 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
GPBMILCE_00943 1.31e-244 - - - L - - - Belongs to the 'phage' integrase family
GPBMILCE_00944 5.33e-170 - - - L - - - DnaD domain protein
GPBMILCE_00947 6.3e-21 - - - - - - - -
GPBMILCE_00953 9.06e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
GPBMILCE_00954 9.75e-101 - - - K - - - Peptidase S24-like
GPBMILCE_00956 1.78e-26 - - - - - - - -
GPBMILCE_00958 2.26e-59 - - - - - - - -
GPBMILCE_00961 1.5e-18 - - - - - - - -
GPBMILCE_00962 3.16e-178 - - - - - - - -
GPBMILCE_00963 8.1e-282 int7 - - L - - - Belongs to the 'phage' integrase family
GPBMILCE_00964 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GPBMILCE_00965 3.81e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GPBMILCE_00966 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GPBMILCE_00967 7.44e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPBMILCE_00968 1.13e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GPBMILCE_00969 1.79e-84 - - - - - - - -
GPBMILCE_00971 1.37e-249 - - - M - - - transferase activity, transferring glycosyl groups
GPBMILCE_00972 6.21e-266 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
GPBMILCE_00973 0.0 - - - M - - - transferase activity, transferring glycosyl groups
GPBMILCE_00974 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
GPBMILCE_00975 9.55e-210 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
GPBMILCE_00976 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GPBMILCE_00977 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GPBMILCE_00978 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GPBMILCE_00980 0.0 - - - M - - - family 8
GPBMILCE_00981 0.0 - - - M - - - family 8
GPBMILCE_00983 1.82e-316 - - - E ko:K03294 - ko00000 amino acid
GPBMILCE_00984 6.64e-233 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPBMILCE_00986 1.37e-269 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
GPBMILCE_00987 4.51e-54 - - - S - - - Cytochrome B5
GPBMILCE_00988 8.47e-08 - - - S - - - Cytochrome B5
GPBMILCE_00989 9.37e-52 - - - S - - - Cytochrome B5
GPBMILCE_00990 5.36e-92 - - - S ko:K02348 - ko00000 Gnat family
GPBMILCE_00991 7.48e-155 - - - GM - - - NmrA-like family
GPBMILCE_00992 2.74e-69 ydeP - - K - - - Transcriptional regulator, HxlR family
GPBMILCE_00993 2.74e-139 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
GPBMILCE_00994 3.33e-102 - - - K - - - Transcriptional regulator, HxlR family
GPBMILCE_00995 7.97e-292 - - - - - - - -
GPBMILCE_00996 7.6e-269 - - - EGP - - - Major Facilitator Superfamily
GPBMILCE_00997 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GPBMILCE_00998 7.17e-146 - - - GM - - - NAD dependent epimerase dehydratase family protein
GPBMILCE_00999 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
GPBMILCE_01000 5.35e-121 - - - S - - - ECF transporter, substrate-specific component
GPBMILCE_01001 1.43e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
GPBMILCE_01002 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
GPBMILCE_01003 6.11e-158 - - - T - - - Putative diguanylate phosphodiesterase
GPBMILCE_01004 7.95e-260 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
GPBMILCE_01005 7.58e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
GPBMILCE_01006 4.85e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
GPBMILCE_01007 4.09e-200 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPBMILCE_01008 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GPBMILCE_01009 3.39e-186 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPBMILCE_01010 2.41e-189 - - - E - - - Glyoxalase-like domain
GPBMILCE_01011 6.23e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
GPBMILCE_01012 1.1e-125 - - - S - - - reductase
GPBMILCE_01014 7.54e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPBMILCE_01015 1.81e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GPBMILCE_01016 5.79e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
GPBMILCE_01017 1.84e-282 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
GPBMILCE_01018 2.52e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
GPBMILCE_01019 4.13e-192 yycI - - S - - - YycH protein
GPBMILCE_01020 6.85e-315 yycH - - S - - - YycH protein
GPBMILCE_01021 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GPBMILCE_01022 3.69e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GPBMILCE_01024 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
GPBMILCE_01025 6.55e-97 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
GPBMILCE_01031 7.89e-168 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
GPBMILCE_01032 1.55e-176 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
GPBMILCE_01033 2.41e-183 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPBMILCE_01034 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
GPBMILCE_01035 4.61e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPBMILCE_01036 6.2e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GPBMILCE_01037 1.21e-286 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GPBMILCE_01038 1.05e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
GPBMILCE_01039 3.95e-203 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
GPBMILCE_01040 2.51e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPBMILCE_01041 1.33e-226 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPBMILCE_01042 2.35e-101 - - - K - - - Transcriptional regulator, MarR family
GPBMILCE_01043 1.76e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPBMILCE_01045 9.39e-256 xerS - - L - - - Belongs to the 'phage' integrase family
GPBMILCE_01046 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
GPBMILCE_01047 7.24e-204 rssA - - S - - - Phospholipase, patatin family
GPBMILCE_01048 1.15e-152 - - - L - - - Integrase
GPBMILCE_01049 7.66e-196 - - - EG - - - EamA-like transporter family
GPBMILCE_01050 7.3e-245 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GPBMILCE_01051 9.45e-168 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
GPBMILCE_01052 7.3e-131 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
GPBMILCE_01053 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
GPBMILCE_01054 8.74e-108 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
GPBMILCE_01055 4.38e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GPBMILCE_01056 1.54e-168 yceF - - P ko:K05794 - ko00000 membrane
GPBMILCE_01057 8.16e-212 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GPBMILCE_01058 2.35e-215 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GPBMILCE_01059 0.0 - - - L - - - Transposase
GPBMILCE_01060 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GPBMILCE_01061 4.79e-307 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
GPBMILCE_01062 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GPBMILCE_01063 3.98e-304 - - - S - - - C4-dicarboxylate anaerobic carrier
GPBMILCE_01064 3.39e-33 - - - S - - - C4-dicarboxylate anaerobic carrier
GPBMILCE_01065 3.18e-160 pgm3 - - G - - - phosphoglycerate mutase family
GPBMILCE_01066 5.07e-56 - - - - - - - -
GPBMILCE_01067 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GPBMILCE_01068 2.84e-264 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
GPBMILCE_01069 2.56e-188 - - - S - - - Alpha beta hydrolase
GPBMILCE_01070 1.02e-279 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GPBMILCE_01071 2.75e-131 - - - - - - - -
GPBMILCE_01073 5.09e-162 - - - M - - - ErfK YbiS YcfS YnhG
GPBMILCE_01074 4.24e-76 - - - L - - - PFAM Integrase catalytic region
GPBMILCE_01075 5.96e-252 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
GPBMILCE_01077 3.97e-302 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 NADH:flavin oxidoreductase / NADH oxidase family
GPBMILCE_01078 1.36e-30 - - - K - - - Transcriptional regulator
GPBMILCE_01083 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
GPBMILCE_01085 1.12e-102 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
GPBMILCE_01086 2.17e-273 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GPBMILCE_01087 1.51e-86 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GPBMILCE_01089 2.25e-100 - - - L - - - Integrase
GPBMILCE_01091 2.5e-171 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
GPBMILCE_01092 3.3e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GPBMILCE_01093 1.31e-193 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GPBMILCE_01094 1.74e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GPBMILCE_01095 7.41e-176 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPBMILCE_01096 3.52e-161 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GPBMILCE_01097 3.14e-195 - - - - - - - -
GPBMILCE_01098 1.28e-308 - - - M - - - Glycosyl transferase
GPBMILCE_01099 3.53e-277 - - - G - - - Glycosyl hydrolases family 8
GPBMILCE_01100 1.41e-66 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GPBMILCE_01101 3.05e-94 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GPBMILCE_01102 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GPBMILCE_01103 3.91e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
GPBMILCE_01104 2.8e-152 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
GPBMILCE_01105 2.66e-114 - - - Q - - - Methyltransferase
GPBMILCE_01106 1.27e-291 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GPBMILCE_01107 1.14e-229 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
GPBMILCE_01108 2.65e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GPBMILCE_01109 4.81e-26 - - - S - - - NADPH-dependent FMN reductase
GPBMILCE_01110 5.22e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GPBMILCE_01111 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPBMILCE_01112 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GPBMILCE_01113 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GPBMILCE_01114 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPBMILCE_01115 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPBMILCE_01116 8.8e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPBMILCE_01117 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPBMILCE_01118 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPBMILCE_01119 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GPBMILCE_01120 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPBMILCE_01121 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPBMILCE_01122 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPBMILCE_01123 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPBMILCE_01124 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPBMILCE_01125 1.06e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPBMILCE_01126 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPBMILCE_01127 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPBMILCE_01128 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GPBMILCE_01129 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GPBMILCE_01130 2.88e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GPBMILCE_01131 4.52e-161 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GPBMILCE_01132 9.82e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPBMILCE_01133 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GPBMILCE_01134 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPBMILCE_01135 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPBMILCE_01136 8.91e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPBMILCE_01137 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GPBMILCE_01138 1.23e-186 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPBMILCE_01139 9.73e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPBMILCE_01140 1.43e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPBMILCE_01141 6.12e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GPBMILCE_01142 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPBMILCE_01143 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GPBMILCE_01144 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GPBMILCE_01145 3.02e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
GPBMILCE_01146 9.16e-111 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPBMILCE_01147 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GPBMILCE_01148 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
GPBMILCE_01149 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
GPBMILCE_01150 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_01151 1.64e-23 - - - K - - - Winged helix-turn-helix DNA-binding
GPBMILCE_01152 1.86e-227 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPBMILCE_01153 3.85e-24 - - - S - - - PFAM Archaeal ATPase
GPBMILCE_01154 4.06e-103 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
GPBMILCE_01155 4.28e-66 - - - S - - - Domain of unknown function (DUF4430)
GPBMILCE_01156 1.02e-10 - - - EG - - - EamA-like transporter family
GPBMILCE_01157 3.2e-185 cobT 2.4.2.21 - F ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
GPBMILCE_01158 4.44e-91 - - - H - - - Uroporphyrinogen-III synthase
GPBMILCE_01159 4.47e-95 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
GPBMILCE_01160 2.56e-152 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPBMILCE_01161 1.41e-98 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobinamide kinase / cobinamide phosphate guanyltransferase
GPBMILCE_01162 3.91e-305 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
GPBMILCE_01163 1.95e-223 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Delta-aminolevulinic acid dehydratase
GPBMILCE_01164 6.56e-174 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GPBMILCE_01165 6.66e-246 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPBMILCE_01166 3.85e-75 cysG 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Putative NAD(P)-binding
GPBMILCE_01167 2.78e-302 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
GPBMILCE_01168 7.19e-155 cbiO - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 part of an ABC transporter complex. Responsible for energy coupling to the transport system
GPBMILCE_01169 1.88e-131 cbiQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GPBMILCE_01170 8.36e-59 cbiN - - P ko:K02009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GPBMILCE_01171 6.68e-159 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GPBMILCE_01172 5.52e-117 cbiL 2.1.1.130, 2.1.1.151 - H ko:K03394 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
GPBMILCE_01173 3.42e-139 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalt chelatase (CbiK)
GPBMILCE_01174 1.32e-220 cobA 2.1.1.107, 4.2.1.75 - H ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
GPBMILCE_01175 1.43e-123 cobK 1.3.1.106, 1.3.1.54 - H ko:K05895 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-6x reductase CbiJ/CobK
GPBMILCE_01176 7.98e-166 cbiH 2.1.1.131 - H ko:K05934 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
GPBMILCE_01177 1.34e-182 cbiG 3.7.1.12 - H ko:K02189 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalamin synthesis G C-terminus
GPBMILCE_01178 8.16e-165 cbiF 2.1.1.133, 2.1.1.271 - H ko:K05936 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
GPBMILCE_01179 1.72e-90 cbiT 2.1.1.196 - H ko:K02191 ko00860,map00860 ko00000,ko00001,ko01000 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
GPBMILCE_01180 6.65e-101 cbiE 2.1.1.289 - H ko:K03399 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
GPBMILCE_01181 1.2e-245 cbiD 2.1.1.195 - H ko:K02188 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GPBMILCE_01182 3.17e-138 cbiC 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-8X methylmutase
GPBMILCE_01183 3.57e-185 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GPBMILCE_01184 2.45e-260 cbiA 6.3.5.11, 6.3.5.9 - F ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
GPBMILCE_01185 4.9e-216 cobD 4.1.1.81 - E ko:K04720 ko00860,map00860 ko00000,ko00001,ko01000 Aminotransferase class I and II
GPBMILCE_01186 1.72e-102 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
GPBMILCE_01187 2e-146 nqo1 - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
GPBMILCE_01188 4.54e-95 ykuP - - C ko:K03839 - ko00000 Flavodoxin
GPBMILCE_01189 1.18e-89 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
GPBMILCE_01190 3.45e-87 - - - P - - - Cadmium resistance transporter
GPBMILCE_01191 1.06e-96 pgm1 - - G - - - phosphoglycerate mutase
GPBMILCE_01192 7.99e-150 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
GPBMILCE_01193 9.15e-72 - - - E ko:K04031 - ko00000 BMC
GPBMILCE_01194 2.5e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPBMILCE_01195 2.5e-258 pduQ - - C ko:K13921 ko00640,map00640 ko00000,ko00001 Iron-containing alcohol dehydrogenase
GPBMILCE_01196 0.0 pduP 1.2.1.87 - C ko:K13922 ko00640,map00640 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
GPBMILCE_01197 1.14e-101 pduO - - S - - - Haem-degrading
GPBMILCE_01198 2.85e-134 - - - S - - - Cobalamin adenosyltransferase
GPBMILCE_01199 5.63e-55 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
GPBMILCE_01200 1.25e-103 - - - S - - - Putative propanediol utilisation
GPBMILCE_01201 1.98e-148 pduL 2.3.1.222 - Q ko:K13923 ko00640,map00640 ko00000,ko00001,ko01000 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
GPBMILCE_01202 3.65e-53 pduA_2 - - CQ ko:K04027 - ko00000 BMC
GPBMILCE_01203 4.63e-75 - - - CQ - - - BMC
GPBMILCE_01204 5.18e-59 pduH - - S - - - Dehydratase medium subunit
GPBMILCE_01205 0.0 pduG - - D - - - Diol dehydratase reactivase ATPase-like domain
GPBMILCE_01206 3.09e-97 pduE 4.2.1.28 - Q ko:K13920 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase small subunit
GPBMILCE_01207 5e-162 pduD 4.2.1.28 - Q ko:K13919 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase medium subunit
GPBMILCE_01208 0.0 pduC 4.2.1.28 - Q ko:K01699 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase large subunit
GPBMILCE_01209 3.41e-170 pduB - - E - - - BMC
GPBMILCE_01210 2.33e-50 - - - CQ - - - BMC
GPBMILCE_01211 1.69e-202 - - - K - - - helix_turn_helix, arabinose operon control protein
GPBMILCE_01212 4.02e-177 eutJ - - E ko:K04024 - ko00000 Hsp70 protein
GPBMILCE_01213 2.7e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GPBMILCE_01214 4.54e-119 - - - - - - - -
GPBMILCE_01215 8.33e-161 - - - G - - - Xylose isomerase domain protein TIM barrel
GPBMILCE_01216 8.61e-214 XK27_12525 - - S - - - AI-2E family transporter
GPBMILCE_01217 2.59e-171 XK27_07210 - - S - - - B3 4 domain
GPBMILCE_01218 8.16e-103 yybA - - K - - - Transcriptional regulator
GPBMILCE_01219 5.25e-118 - - - K - - - Domain of unknown function (DUF1836)
GPBMILCE_01220 3.16e-114 - - - GM - - - epimerase
GPBMILCE_01221 1.39e-198 - - - V - - - (ABC) transporter
GPBMILCE_01222 1.67e-307 yhdP - - S - - - Transporter associated domain
GPBMILCE_01223 1.98e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
GPBMILCE_01224 3.68e-97 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
GPBMILCE_01225 2.64e-246 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
GPBMILCE_01226 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPBMILCE_01227 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPBMILCE_01228 2.6e-54 - - - - - - - -
GPBMILCE_01229 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
GPBMILCE_01230 5.08e-77 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
GPBMILCE_01231 2.07e-61 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
GPBMILCE_01232 6.65e-104 usp5 - - T - - - universal stress protein
GPBMILCE_01233 5.98e-14 - - - - - - - -
GPBMILCE_01234 0.0 - - - L - - - Helicase C-terminal domain protein
GPBMILCE_01235 2.29e-60 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
GPBMILCE_01236 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPBMILCE_01237 5.06e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
GPBMILCE_01238 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPBMILCE_01239 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GPBMILCE_01240 1.36e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPBMILCE_01241 1.11e-260 camS - - S - - - sex pheromone
GPBMILCE_01242 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPBMILCE_01243 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GPBMILCE_01244 8.91e-270 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPBMILCE_01245 1.94e-130 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GPBMILCE_01246 3.07e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
GPBMILCE_01247 4.46e-180 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
GPBMILCE_01249 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
GPBMILCE_01250 4.07e-224 - - - M - - - LPXTG-motif cell wall anchor domain protein
GPBMILCE_01251 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
GPBMILCE_01252 6.57e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
GPBMILCE_01253 5.11e-188 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GPBMILCE_01254 1.1e-157 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
GPBMILCE_01257 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPBMILCE_01258 9.61e-213 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
GPBMILCE_01259 2.11e-290 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GPBMILCE_01260 3.03e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GPBMILCE_01261 9.02e-201 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
GPBMILCE_01262 3e-224 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GPBMILCE_01263 2.05e-183 - - - V - - - DNA restriction-modification system
GPBMILCE_01264 1.39e-75 - - - V - - - Domain of unknown function (DUF3883)
GPBMILCE_01265 2.91e-231 apc3 - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
GPBMILCE_01266 4.67e-160 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
GPBMILCE_01267 6.05e-185 - - - F ko:K10974 - ko00000,ko02000 Permease for cytosine/purines, uracil, thiamine, allantoin
GPBMILCE_01268 1.17e-29 - - - L - - - Helix-turn-helix domain
GPBMILCE_01269 9.31e-51 - - - L ko:K07497 - ko00000 hmm pf00665
GPBMILCE_01270 4.31e-52 - - - - - - - -
GPBMILCE_01271 8.53e-136 - - - L - - - Integrase
GPBMILCE_01273 2.26e-61 - - - S - - - Phage derived protein Gp49-like (DUF891)
GPBMILCE_01274 1.87e-42 - - - K - - - Helix-turn-helix domain
GPBMILCE_01276 1.53e-283 - - - - - - - -
GPBMILCE_01277 2.31e-201 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
GPBMILCE_01278 2.67e-60 - - - - - - - -
GPBMILCE_01279 8.81e-89 - - - K - - - Transcriptional regulator
GPBMILCE_01280 2.24e-301 - - - EGP - - - Major Facilitator
GPBMILCE_01281 6.65e-145 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
GPBMILCE_01282 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
GPBMILCE_01283 1.73e-148 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
GPBMILCE_01284 1.18e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPBMILCE_01285 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GPBMILCE_01286 1.58e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GPBMILCE_01287 8.62e-66 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
GPBMILCE_01288 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
GPBMILCE_01289 1.38e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GPBMILCE_01290 5.5e-199 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPBMILCE_01291 5.93e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GPBMILCE_01292 1.79e-214 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GPBMILCE_01293 5.04e-175 lutC - - S ko:K00782 - ko00000 LUD domain
GPBMILCE_01294 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
GPBMILCE_01295 2.03e-208 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
GPBMILCE_01296 6.81e-222 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GPBMILCE_01297 7.12e-171 - - - O - - - Bacterial dnaA protein
GPBMILCE_01298 3.68e-145 - - - L - - - Integrase core domain
GPBMILCE_01299 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
GPBMILCE_01300 3.11e-218 - - - L ko:K07497 - ko00000 Integrase core domain
GPBMILCE_01301 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GPBMILCE_01302 1.07e-217 - - - S - - - Protein of unknown function DUF262
GPBMILCE_01303 5.33e-103 - - - S - - - Protein of unknown function (DUF805)
GPBMILCE_01304 1.26e-60 - - - - - - - -
GPBMILCE_01305 1.81e-41 - - - - - - - -
GPBMILCE_01306 2.2e-62 - - - - - - - -
GPBMILCE_01307 5.91e-125 - - - K - - - Acetyltransferase (GNAT) domain
GPBMILCE_01308 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GPBMILCE_01309 1.05e-292 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
GPBMILCE_01310 1.62e-232 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
GPBMILCE_01311 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GPBMILCE_01312 1.14e-124 - - - - - - - -
GPBMILCE_01313 3.09e-35 - - - - - - - -
GPBMILCE_01314 2.71e-81 asp1 - - S - - - Asp23 family, cell envelope-related function
GPBMILCE_01315 7.63e-117 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
GPBMILCE_01317 9.14e-66 - - - - - - - -
GPBMILCE_01318 2.49e-87 - - - S - - - Belongs to the HesB IscA family
GPBMILCE_01319 4.63e-255 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPBMILCE_01320 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPBMILCE_01321 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
GPBMILCE_01322 6.21e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GPBMILCE_01323 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPBMILCE_01324 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPBMILCE_01325 4.92e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPBMILCE_01326 2.71e-51 - - - S - - - Protein of unknown function (DUF2508)
GPBMILCE_01327 2.14e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPBMILCE_01328 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
GPBMILCE_01329 1.29e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GPBMILCE_01330 3.71e-76 yabA - - L - - - Involved in initiation control of chromosome replication
GPBMILCE_01331 3.7e-199 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPBMILCE_01332 6.09e-176 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
GPBMILCE_01333 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GPBMILCE_01334 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPBMILCE_01335 3.23e-222 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GPBMILCE_01336 6.02e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GPBMILCE_01337 5.14e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
GPBMILCE_01338 2.06e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GPBMILCE_01339 8.52e-245 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPBMILCE_01340 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GPBMILCE_01341 8e-275 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GPBMILCE_01342 0.0 eriC - - P ko:K03281 - ko00000 chloride
GPBMILCE_01343 3.53e-100 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GPBMILCE_01344 1.96e-138 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
GPBMILCE_01345 8.34e-180 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_01346 2.35e-139 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GPBMILCE_01347 1.77e-207 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
GPBMILCE_01348 3.87e-97 ywnA - - K - - - Transcriptional regulator
GPBMILCE_01349 1.83e-197 - - - GM - - - NAD(P)H-binding
GPBMILCE_01350 4.44e-11 - - - - - - - -
GPBMILCE_01351 5.23e-276 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
GPBMILCE_01352 0.0 cadA - - P - - - P-type ATPase
GPBMILCE_01353 1.31e-161 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
GPBMILCE_01354 1.14e-178 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
GPBMILCE_01355 8.43e-165 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPBMILCE_01356 1.79e-101 - - - S - - - Flavodoxin
GPBMILCE_01357 3.25e-84 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
GPBMILCE_01358 4.04e-48 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
GPBMILCE_01359 5.25e-279 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
GPBMILCE_01360 4.74e-213 - - - H - - - geranyltranstransferase activity
GPBMILCE_01361 9.46e-235 - - - - - - - -
GPBMILCE_01362 3.11e-26 - - - - - - - -
GPBMILCE_01363 2.22e-151 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
GPBMILCE_01364 7.54e-242 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
GPBMILCE_01365 1.56e-60 - - - - - - - -
GPBMILCE_01366 2.03e-136 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GPBMILCE_01367 9.66e-110 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
GPBMILCE_01368 8.93e-291 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
GPBMILCE_01369 1.65e-107 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
GPBMILCE_01370 1.35e-238 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
GPBMILCE_01371 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPBMILCE_01372 3.8e-56 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
GPBMILCE_01373 6.35e-69 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
GPBMILCE_01374 5.96e-240 ybcH - - D ko:K06889 - ko00000 Alpha beta
GPBMILCE_01375 1.3e-95 - - - K - - - Transcriptional regulator
GPBMILCE_01376 3.46e-207 - - - - - - - -
GPBMILCE_01377 9.77e-231 - - - C - - - Zinc-binding dehydrogenase
GPBMILCE_01378 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
GPBMILCE_01379 6.79e-271 - - - EGP - - - Major Facilitator
GPBMILCE_01380 3.18e-11 - - - - - - - -
GPBMILCE_01381 1.78e-83 - - - - - - - -
GPBMILCE_01382 1.42e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
GPBMILCE_01383 1.24e-104 uspA3 - - T - - - universal stress protein
GPBMILCE_01384 0.0 fusA1 - - J - - - elongation factor G
GPBMILCE_01385 2.17e-213 - - - GK - - - ROK family
GPBMILCE_01386 9.75e-311 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GPBMILCE_01387 4.49e-180 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
GPBMILCE_01388 1.05e-310 - - - E - - - amino acid
GPBMILCE_01389 8.53e-95 - - - - - - - -
GPBMILCE_01390 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GPBMILCE_01391 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
GPBMILCE_01392 0.0 - - - M - - - domain protein
GPBMILCE_01393 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GPBMILCE_01394 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GPBMILCE_01395 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GPBMILCE_01396 4.03e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GPBMILCE_01397 2.11e-160 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GPBMILCE_01398 2.69e-116 yclK - - T - - - Histidine kinase
GPBMILCE_01399 5.74e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
GPBMILCE_01400 6.64e-99 - - - L - - - PFAM Integrase catalytic region
GPBMILCE_01401 3.13e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GPBMILCE_01402 1.21e-215 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPBMILCE_01403 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPBMILCE_01404 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPBMILCE_01405 1.96e-65 ylxQ - - J - - - ribosomal protein
GPBMILCE_01406 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
GPBMILCE_01407 1.68e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GPBMILCE_01408 1.1e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GPBMILCE_01409 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPBMILCE_01410 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GPBMILCE_01411 5.46e-297 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GPBMILCE_01412 1.18e-177 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GPBMILCE_01413 1.83e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPBMILCE_01414 4.23e-123 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GPBMILCE_01415 2.21e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GPBMILCE_01416 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPBMILCE_01417 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GPBMILCE_01418 5.9e-233 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPBMILCE_01419 6.79e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
GPBMILCE_01420 5.9e-182 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
GPBMILCE_01421 7.51e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
GPBMILCE_01422 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
GPBMILCE_01423 2.7e-47 ynzC - - S - - - UPF0291 protein
GPBMILCE_01424 4.18e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPBMILCE_01425 2.88e-270 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
GPBMILCE_01426 7.77e-159 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPBMILCE_01428 4.6e-77 - - - - - - - -
GPBMILCE_01429 1.31e-84 - - - - - - - -
GPBMILCE_01431 6.53e-126 - - - S ko:K06919 - ko00000 D5 N terminal like
GPBMILCE_01432 3.93e-51 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
GPBMILCE_01439 1.11e-25 - - - S - - - Helix-turn-helix domain
GPBMILCE_01440 4.27e-13 ansR - - K - - - Transcriptional regulator
GPBMILCE_01441 1.43e-168 int2 - - L - - - Belongs to the 'phage' integrase family
GPBMILCE_01442 1.47e-120 - - - - - - - -
GPBMILCE_01443 1.46e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPBMILCE_01444 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GPBMILCE_01445 3.87e-200 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GPBMILCE_01446 3.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GPBMILCE_01447 3.8e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPBMILCE_01448 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GPBMILCE_01449 2.44e-20 - - - - - - - -
GPBMILCE_01450 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
GPBMILCE_01451 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GPBMILCE_01452 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPBMILCE_01453 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GPBMILCE_01454 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPBMILCE_01455 3.58e-208 - - - S - - - Tetratricopeptide repeat
GPBMILCE_01456 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPBMILCE_01457 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPBMILCE_01458 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GPBMILCE_01459 9.21e-200 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GPBMILCE_01460 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GPBMILCE_01461 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
GPBMILCE_01462 3.4e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
GPBMILCE_01463 3.51e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GPBMILCE_01464 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPBMILCE_01465 6.8e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
GPBMILCE_01466 6.37e-60 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
GPBMILCE_01467 7.54e-284 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GPBMILCE_01468 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GPBMILCE_01469 3.52e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
GPBMILCE_01470 7.04e-63 yktA - - S - - - Belongs to the UPF0223 family
GPBMILCE_01471 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
GPBMILCE_01472 2.13e-311 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPBMILCE_01473 5.45e-231 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
GPBMILCE_01474 2.44e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
GPBMILCE_01475 1.38e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPBMILCE_01476 6.08e-102 - - - - - - - -
GPBMILCE_01477 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
GPBMILCE_01478 1.69e-229 - - - I - - - Diacylglycerol kinase catalytic
GPBMILCE_01479 4.37e-39 - - - - - - - -
GPBMILCE_01480 3.3e-265 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
GPBMILCE_01481 3.12e-121 - - - L - - - PFAM Integrase catalytic region
GPBMILCE_01487 2.68e-11 - - - S - - - Antirestriction protein (ArdA)
GPBMILCE_01498 5.11e-29 - - - - - - - -
GPBMILCE_01500 2.48e-15 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GPBMILCE_01512 7.04e-118 - - - - - - - -
GPBMILCE_01513 1.8e-84 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
GPBMILCE_01514 1.57e-56 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
GPBMILCE_01515 6.94e-117 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
GPBMILCE_01516 1.08e-112 - - - T - - - EAL domain
GPBMILCE_01517 4.18e-168 - - - F - - - glutamine amidotransferase
GPBMILCE_01518 1.74e-85 - - - - - - - -
GPBMILCE_01519 2.22e-145 - - - GM - - - NAD(P)H-binding
GPBMILCE_01520 3.43e-110 - - - S - - - membrane
GPBMILCE_01521 1.28e-105 - - - S - - - membrane
GPBMILCE_01522 6.78e-136 - - - K - - - Transcriptional regulator C-terminal region
GPBMILCE_01523 7.26e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
GPBMILCE_01524 3.02e-52 - - - K - - - Transcriptional regulator
GPBMILCE_01525 5.61e-75 - - - K - - - Transcriptional regulator
GPBMILCE_01526 1.9e-233 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
GPBMILCE_01527 1.45e-214 ypuA - - S - - - Protein of unknown function (DUF1002)
GPBMILCE_01528 6.88e-84 - - - GM - - - NAD(P)H-binding
GPBMILCE_01529 1.19e-119 - - - K - - - Virulence activator alpha C-term
GPBMILCE_01530 2.49e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
GPBMILCE_01531 2.05e-195 - - - S - - - Alpha beta hydrolase
GPBMILCE_01532 8.09e-44 - - - S ko:K06889 - ko00000 thiolester hydrolase activity
GPBMILCE_01533 7.41e-114 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GPBMILCE_01534 2.15e-203 lysR - - K - - - Transcriptional regulator
GPBMILCE_01535 2.67e-111 - - - C - - - Flavodoxin
GPBMILCE_01537 5.28e-76 - - - - - - - -
GPBMILCE_01538 7.55e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GPBMILCE_01539 2.7e-280 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
GPBMILCE_01540 5.77e-104 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
GPBMILCE_01541 2.58e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPBMILCE_01542 1.33e-275 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GPBMILCE_01543 1.43e-177 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GPBMILCE_01544 9.32e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPBMILCE_01545 1.64e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GPBMILCE_01546 2.66e-111 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GPBMILCE_01547 5.89e-314 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GPBMILCE_01548 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GPBMILCE_01549 3.17e-219 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPBMILCE_01550 1.55e-46 - - - M - - - LPXTG-motif cell wall anchor domain protein
GPBMILCE_01551 1.1e-187 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
GPBMILCE_01552 1.04e-90 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPBMILCE_01553 1.47e-25 - - - - - - - -
GPBMILCE_01554 6.62e-66 tnpR1 - - L - - - Resolvase, N terminal domain
GPBMILCE_01555 1.41e-67 - - - - - - - -
GPBMILCE_01557 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
GPBMILCE_01558 9.7e-94 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
GPBMILCE_01559 2.4e-191 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GPBMILCE_01560 7.84e-49 - - - K - - - Transcriptional regulator
GPBMILCE_01561 5.32e-102 arbZ - - I - - - Phosphate acyltransferases
GPBMILCE_01562 8.37e-99 arbY - - M - - - family 8
GPBMILCE_01563 2.14e-98 arbx - - M - - - Glycosyl transferase family 8
GPBMILCE_01564 2.38e-68 arbV - - I - - - Phosphate acyltransferases
GPBMILCE_01565 3.91e-215 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GPBMILCE_01566 1.51e-75 cadX - - K ko:K21903 - ko00000,ko03000 Bacterial regulatory protein, arsR family
GPBMILCE_01567 3.39e-131 cadD - - P - - - Cadmium resistance transporter
GPBMILCE_01569 1.07e-119 - - - L - - - Integrase
GPBMILCE_01570 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
GPBMILCE_01571 5.97e-91 - - - L - - - Helix-turn-helix domain
GPBMILCE_01572 1.33e-173 - - - L ko:K07497 - ko00000 hmm pf00665
GPBMILCE_01573 1.99e-38 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GPBMILCE_01574 2.05e-77 - - - - - - - -
GPBMILCE_01575 2.36e-299 - - - - - - - -
GPBMILCE_01577 7.42e-59 - - - - - - - -
GPBMILCE_01578 4.34e-45 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
GPBMILCE_01579 1.21e-135 - - - L - - - Integrase
GPBMILCE_01580 1.31e-110 - - - D - - - AAA domain
GPBMILCE_01581 1.03e-53 - - - - - - - -
GPBMILCE_01584 2.91e-311 - - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 Tetracycline resistance protein TetA
GPBMILCE_01585 6.97e-24 yrkL - - S - - - Flavodoxin-like fold
GPBMILCE_01586 0.0 - - - S - - - Peptidase, M23
GPBMILCE_01587 0.0 bamA - - GM ko:K07277,ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029 domain, Protein
GPBMILCE_01588 1.19e-84 - - - K - - - Transcriptional regulator, GntR family
GPBMILCE_01589 2.02e-56 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_01590 6.4e-113 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_01591 7.87e-146 - - - - - - - -
GPBMILCE_01592 1.35e-182 - - - G - - - MucBP domain
GPBMILCE_01593 7.43e-129 - - - S - - - Pfam:DUF3816
GPBMILCE_01594 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
GPBMILCE_01595 1.38e-37 - - - - - - - -
GPBMILCE_01596 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
GPBMILCE_01597 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPBMILCE_01598 1.08e-110 - - - S - - - Glycosyltransferase like family
GPBMILCE_01599 1.29e-105 - - - M - - - Domain of unknown function (DUF4422)
GPBMILCE_01600 5.19e-49 - - - M - - - biosynthesis protein
GPBMILCE_01601 5.58e-122 cps3F - - - - - - -
GPBMILCE_01602 3.68e-123 - - - M - - - Glycosyltransferase like family 2
GPBMILCE_01603 1.23e-145 - - - S - - - Glycosyltransferase like family 2
GPBMILCE_01604 8.61e-94 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
GPBMILCE_01605 4.63e-270 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GPBMILCE_01606 6.1e-279 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
GPBMILCE_01607 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
GPBMILCE_01609 8.24e-160 - - - S - - - polysaccharide biosynthetic process
GPBMILCE_01610 1.23e-38 - - - - - - - -
GPBMILCE_01611 2.25e-55 cps1B - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 transferase activity, transferring glycosyl groups
GPBMILCE_01613 3.2e-80 - - - - - - - -
GPBMILCE_01614 1.42e-62 - - - M - - - Glycosyl transferase family 2
GPBMILCE_01615 1.79e-66 capM - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
GPBMILCE_01616 5.26e-159 ywqD - - D - - - Capsular exopolysaccharide family
GPBMILCE_01617 4.78e-192 epsB - - M - - - biosynthesis protein
GPBMILCE_01618 1.15e-214 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GPBMILCE_01619 6.74e-53 - - - K - - - Transcriptional regulator, HxlR family
GPBMILCE_01620 7.13e-227 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPBMILCE_01621 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
GPBMILCE_01622 7.66e-88 yqhL - - P - - - Rhodanese-like protein
GPBMILCE_01623 1.02e-234 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
GPBMILCE_01624 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
GPBMILCE_01625 1.38e-59 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
GPBMILCE_01626 1.43e-16 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
GPBMILCE_01627 9.34e-130 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPBMILCE_01628 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GPBMILCE_01629 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GPBMILCE_01630 0.0 - - - S - - - membrane
GPBMILCE_01631 1.33e-91 yneR - - S - - - Belongs to the HesB IscA family
GPBMILCE_01632 5.39e-64 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
GPBMILCE_01633 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
GPBMILCE_01634 2.32e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
GPBMILCE_01635 5.43e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
GPBMILCE_01636 1.59e-303 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
GPBMILCE_01637 2.23e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPBMILCE_01638 9.11e-106 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
GPBMILCE_01639 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
GPBMILCE_01640 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
GPBMILCE_01641 3.86e-205 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
GPBMILCE_01642 5.87e-147 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
GPBMILCE_01643 3.47e-50 - - - S - - - Cytochrome B5
GPBMILCE_01644 1.11e-201 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GPBMILCE_01645 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
GPBMILCE_01646 1.54e-191 - - - O - - - Band 7 protein
GPBMILCE_01647 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
GPBMILCE_01648 3.39e-168 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
GPBMILCE_01649 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
GPBMILCE_01650 4.38e-161 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
GPBMILCE_01651 3.4e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GPBMILCE_01652 5.79e-214 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
GPBMILCE_01653 2.43e-241 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
GPBMILCE_01654 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
GPBMILCE_01655 5.52e-119 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
GPBMILCE_01656 2.55e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GPBMILCE_01657 4.11e-274 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
GPBMILCE_01658 1.71e-217 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
GPBMILCE_01659 6.02e-219 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
GPBMILCE_01660 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GPBMILCE_01661 9.09e-113 ypmB - - S - - - Protein conserved in bacteria
GPBMILCE_01662 1.75e-161 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
GPBMILCE_01663 5.69e-207 - - - EG - - - EamA-like transporter family
GPBMILCE_01664 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
GPBMILCE_01665 7.01e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPBMILCE_01666 1.17e-135 ypsA - - S - - - Belongs to the UPF0398 family
GPBMILCE_01667 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GPBMILCE_01668 1.01e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
GPBMILCE_01669 3.43e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GPBMILCE_01670 2.2e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
GPBMILCE_01671 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
GPBMILCE_01672 6.71e-92 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPBMILCE_01673 5.61e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GPBMILCE_01674 9.15e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
GPBMILCE_01675 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GPBMILCE_01676 0.0 FbpA - - K - - - Fibronectin-binding protein
GPBMILCE_01677 1.2e-206 - - - S - - - EDD domain protein, DegV family
GPBMILCE_01678 7.49e-124 - - - - - - - -
GPBMILCE_01679 3.04e-154 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GPBMILCE_01680 2.07e-202 gspA - - M - - - family 8
GPBMILCE_01681 9.91e-205 - - - S - - - Alpha beta hydrolase
GPBMILCE_01682 7.5e-122 - - - K - - - Acetyltransferase (GNAT) domain
GPBMILCE_01683 2.88e-306 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
GPBMILCE_01684 1.02e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
GPBMILCE_01685 2.99e-218 yvgN - - C - - - Aldo keto reductase
GPBMILCE_01686 7.79e-204 rlrB - - K - - - LysR substrate binding domain protein
GPBMILCE_01687 2.91e-109 - - - C - - - Flavodoxin
GPBMILCE_01688 6.14e-104 - - - S - - - Cupin domain
GPBMILCE_01689 9.49e-98 - - - S - - - UPF0756 membrane protein
GPBMILCE_01690 2.9e-309 - - - U - - - Belongs to the major facilitator superfamily
GPBMILCE_01691 2.39e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
GPBMILCE_01692 9.45e-315 yhdP - - S - - - Transporter associated domain
GPBMILCE_01693 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
GPBMILCE_01694 1.43e-185 - - - S - - - DUF218 domain
GPBMILCE_01695 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPBMILCE_01696 1.3e-78 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPBMILCE_01697 6.28e-73 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPBMILCE_01698 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
GPBMILCE_01699 2.04e-158 - - - S - - - SNARE associated Golgi protein
GPBMILCE_01700 1.22e-289 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
GPBMILCE_01701 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPBMILCE_01703 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
GPBMILCE_01704 1.4e-201 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
GPBMILCE_01705 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPBMILCE_01706 4.35e-148 sthIR 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
GPBMILCE_01707 4.29e-205 - 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
GPBMILCE_01708 1.33e-19 - - - - - - - -
GPBMILCE_01711 1.33e-162 - - - L - - - Helix-turn-helix domain
GPBMILCE_01712 3.88e-202 - - - L ko:K07497 - ko00000 hmm pf00665
GPBMILCE_01713 3.42e-233 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GPBMILCE_01714 5.46e-233 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
GPBMILCE_01715 4.28e-182 - - - V - - - Beta-lactamase enzyme family
GPBMILCE_01716 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
GPBMILCE_01717 6.33e-275 - - - EGP - - - Transporter, major facilitator family protein
GPBMILCE_01718 0.0 arcT - - E - - - Dipeptidase
GPBMILCE_01719 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
GPBMILCE_01720 7.42e-228 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
GPBMILCE_01721 4.83e-215 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GPBMILCE_01722 5.26e-174 - - - I - - - alpha/beta hydrolase fold
GPBMILCE_01723 8.07e-53 - - - D - - - nuclear chromosome segregation
GPBMILCE_01725 3.49e-58 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPBMILCE_01726 7.27e-178 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
GPBMILCE_01727 1.9e-12 - - - - - - - -
GPBMILCE_01731 4.67e-166 - - - M - - - PFAM NLP P60 protein
GPBMILCE_01732 3.16e-233 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GPBMILCE_01733 2.27e-194 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GPBMILCE_01734 5.63e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_01735 5.77e-121 - - - P - - - Cadmium resistance transporter
GPBMILCE_01736 1.14e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
GPBMILCE_01737 1.25e-43 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPBMILCE_01738 8.52e-144 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
GPBMILCE_01739 0.0 - - - S - - - SEC-C Motif Domain Protein
GPBMILCE_01740 1.19e-65 - - - - - - - -
GPBMILCE_01741 1.87e-178 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPBMILCE_01742 6.12e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GPBMILCE_01743 5.25e-149 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GPBMILCE_01744 6.19e-277 - - - P - - - Chloride transporter, ClC family
GPBMILCE_01745 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
GPBMILCE_01746 5.65e-143 - - - I - - - Acid phosphatase homologues
GPBMILCE_01748 9.94e-36 - - - K - - - UTRA
GPBMILCE_01749 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
GPBMILCE_01750 8.05e-195 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GPBMILCE_01751 5.94e-82 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
GPBMILCE_01752 1.1e-261 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPBMILCE_01753 7.93e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GPBMILCE_01754 3.14e-309 - - - M - - - NlpC/P60 family
GPBMILCE_01755 7.66e-314 - - - M - - - NlpC/P60 family
GPBMILCE_01756 9.82e-38 - 3.2.1.26, 3.2.1.65 GH32 G ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
GPBMILCE_01757 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPBMILCE_01758 1.38e-300 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GPBMILCE_01759 9.19e-233 yueF - - S - - - AI-2E family transporter
GPBMILCE_01760 6.64e-99 - - - L - - - PFAM Integrase catalytic region
GPBMILCE_01761 1.77e-54 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
GPBMILCE_01762 1.36e-95 - - - S - - - Protein of unknown function (DUF3290)
GPBMILCE_01763 1.98e-147 - - - S - - - Protein of unknown function (DUF421)
GPBMILCE_01764 4.22e-209 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GPBMILCE_01765 1.01e-28 - - - - - - - -
GPBMILCE_01766 8e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
GPBMILCE_01767 4.68e-197 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GPBMILCE_01768 2.54e-60 yrvD - - S - - - Pfam:DUF1049
GPBMILCE_01770 1.47e-41 - - - S - - - Phage derived protein Gp49-like (DUF891)
GPBMILCE_01771 2.6e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
GPBMILCE_01772 7.05e-101 - - - I - - - alpha/beta hydrolase fold
GPBMILCE_01773 3.55e-147 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
GPBMILCE_01774 3.05e-69 - - - - - - - -
GPBMILCE_01775 2.94e-239 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPBMILCE_01776 4.93e-35 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPBMILCE_01777 1.15e-204 - - - - - - - -
GPBMILCE_01778 3.7e-123 - - - K - - - acetyltransferase
GPBMILCE_01779 2.19e-97 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GPBMILCE_01780 7.73e-59 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GPBMILCE_01781 6.63e-202 - - - K - - - LysR substrate binding domain
GPBMILCE_01782 1.62e-256 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
GPBMILCE_01783 1.24e-76 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPBMILCE_01785 2.08e-215 - - - - - - - -
GPBMILCE_01786 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPBMILCE_01787 1.54e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
GPBMILCE_01788 1.96e-166 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
GPBMILCE_01789 5.02e-134 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
GPBMILCE_01790 2.12e-253 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPBMILCE_01791 1.35e-167 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPBMILCE_01792 6.3e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPBMILCE_01793 2.46e-175 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPBMILCE_01794 6.34e-182 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
GPBMILCE_01795 3.87e-283 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GPBMILCE_01796 3.99e-231 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPBMILCE_01797 9.29e-290 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GPBMILCE_01798 1.08e-96 - - - - - - - -
GPBMILCE_01799 3.67e-255 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
GPBMILCE_01800 1.36e-35 - - - - - - - -
GPBMILCE_01801 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
GPBMILCE_01802 8.63e-213 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GPBMILCE_01803 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
GPBMILCE_01804 1.35e-263 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
GPBMILCE_01805 2.87e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPBMILCE_01806 5.46e-207 mleR - - K - - - LysR family
GPBMILCE_01807 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
GPBMILCE_01808 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GPBMILCE_01809 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GPBMILCE_01810 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GPBMILCE_01811 7.21e-205 - - - K - - - LysR family
GPBMILCE_01812 0.0 - - - S - - - Putative threonine/serine exporter
GPBMILCE_01813 2.22e-151 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
GPBMILCE_01814 0.0 qacA - - EGP - - - Major Facilitator
GPBMILCE_01815 1.93e-241 - - - I - - - Alpha beta
GPBMILCE_01816 5.59e-134 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
GPBMILCE_01817 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPBMILCE_01819 2.24e-205 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GPBMILCE_01820 1.91e-153 - - - S - - - Domain of unknown function (DUF4811)
GPBMILCE_01821 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
GPBMILCE_01822 1.26e-96 - - - K - - - MerR HTH family regulatory protein
GPBMILCE_01823 9.15e-72 - - - - - - - -
GPBMILCE_01824 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPBMILCE_01825 8.69e-277 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GPBMILCE_01826 2.11e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GPBMILCE_01827 1.06e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GPBMILCE_01828 1.29e-193 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GPBMILCE_01829 1.39e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_01830 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
GPBMILCE_01831 4.71e-142 - - - S - - - VIT family
GPBMILCE_01832 3.11e-153 - - - S - - - membrane
GPBMILCE_01833 4.04e-212 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
GPBMILCE_01834 2.32e-161 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
GPBMILCE_01835 2.17e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
GPBMILCE_01836 1.72e-165 - - - S - - - Putative threonine/serine exporter
GPBMILCE_01837 5.02e-105 - - - S - - - Threonine/Serine exporter, ThrE
GPBMILCE_01838 1.14e-152 - - - I - - - phosphatase
GPBMILCE_01840 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
GPBMILCE_01841 7.78e-150 dgk2 - - F - - - deoxynucleoside kinase
GPBMILCE_01847 1.45e-167 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
GPBMILCE_01848 4.62e-21 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
GPBMILCE_01849 8.94e-250 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GPBMILCE_01850 1.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
GPBMILCE_01851 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GPBMILCE_01852 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
GPBMILCE_01853 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPBMILCE_01854 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPBMILCE_01855 1.15e-263 - - - - - - - -
GPBMILCE_01856 1.97e-153 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
GPBMILCE_01857 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPBMILCE_01858 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GPBMILCE_01859 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPBMILCE_01860 6.54e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GPBMILCE_01861 7.22e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPBMILCE_01862 7.45e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
GPBMILCE_01863 4.67e-146 yjbH - - Q - - - Thioredoxin
GPBMILCE_01864 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GPBMILCE_01865 2.41e-264 coiA - - S ko:K06198 - ko00000 Competence protein
GPBMILCE_01866 3.28e-156 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GPBMILCE_01867 2.02e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GPBMILCE_01868 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
GPBMILCE_01869 1.76e-252 bamA - - GM ko:K07277,ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029 domain, Protein
GPBMILCE_01870 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
GPBMILCE_01871 1.73e-56 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
GPBMILCE_01872 3.58e-34 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
GPBMILCE_01873 6.64e-99 - - - L - - - PFAM Integrase catalytic region
GPBMILCE_01874 3.74e-53 - - - - - - - -
GPBMILCE_01875 0.0 ydaO - - E - - - amino acid
GPBMILCE_01876 0.0 - - - E - - - amino acid
GPBMILCE_01877 3.11e-106 - - - S ko:K19055 - ko00000,ko01000,ko03016 YbaK proline--tRNA ligase associated domain protein
GPBMILCE_01878 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GPBMILCE_01879 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPBMILCE_01881 1.34e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GPBMILCE_01882 4.67e-122 - - - S - - - PFAM Archaeal ATPase
GPBMILCE_01883 3.81e-62 - - - - - - - -
GPBMILCE_01885 3.44e-47 - - - S - - - PD-(D/E)XK nuclease family transposase
GPBMILCE_01886 8.76e-205 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
GPBMILCE_01887 3.05e-41 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
GPBMILCE_01888 7.45e-315 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
GPBMILCE_01889 1.16e-114 XK27_07210 - - S - - - B3 4 domain
GPBMILCE_01890 8.65e-119 - - - - - - - -
GPBMILCE_01891 5.47e-80 pnb - - C - - - nitroreductase
GPBMILCE_01892 7.72e-178 - - - IQ - - - KR domain
GPBMILCE_01893 1.47e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
GPBMILCE_01894 8.59e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GPBMILCE_01895 4.68e-314 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_01896 2.91e-147 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GPBMILCE_01897 6.5e-71 - - - - - - - -
GPBMILCE_01898 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
GPBMILCE_01899 4.59e-272 - - - L - - - Integrase core domain
GPBMILCE_01900 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GPBMILCE_01901 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
GPBMILCE_01902 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
GPBMILCE_01903 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPBMILCE_01904 4.72e-108 - - - - - - - -
GPBMILCE_01905 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
GPBMILCE_01906 5.8e-143 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
GPBMILCE_01907 1.3e-100 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GPBMILCE_01908 7.55e-286 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GPBMILCE_01909 3.39e-124 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GPBMILCE_01910 5.59e-249 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPBMILCE_01913 2.19e-13 - - - S - - - 23S rRNA methylase leader peptide (ErmC)
GPBMILCE_01914 4.32e-171 ermA 2.1.1.184 - J ko:K00561 - br01600,ko00000,ko01000,ko01504,ko03009 Ribosomal RNA adenine dimethylase
GPBMILCE_01918 8.28e-114 - - - L - - - Transposase
GPBMILCE_01919 3.98e-229 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GPBMILCE_01920 7.37e-275 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
GPBMILCE_01921 8.9e-131 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
GPBMILCE_01923 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPBMILCE_01924 2.58e-230 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
GPBMILCE_01925 2.79e-184 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
GPBMILCE_01926 1.51e-126 - - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GPBMILCE_01927 1.33e-170 - 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_01928 8.56e-162 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
GPBMILCE_01929 2.79e-193 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
GPBMILCE_01930 1.29e-231 - - - G - - - Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
GPBMILCE_01931 3.31e-37 - - - S - - - YSIRK type signal peptide
GPBMILCE_01932 1.85e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GPBMILCE_01933 6.64e-279 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GPBMILCE_01934 2.7e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GPBMILCE_01935 4.99e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
GPBMILCE_01937 3.96e-178 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GPBMILCE_01938 0.0 yhaN - - L - - - AAA domain
GPBMILCE_01939 2.62e-282 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
GPBMILCE_01940 3.75e-77 yheA - - S - - - Belongs to the UPF0342 family
GPBMILCE_01941 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GPBMILCE_01942 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GPBMILCE_01943 2.15e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GPBMILCE_01944 3.88e-213 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GPBMILCE_01946 1.49e-54 - - - - - - - -
GPBMILCE_01947 9.3e-61 - - - - - - - -
GPBMILCE_01948 9.39e-277 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
GPBMILCE_01949 2.97e-136 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
GPBMILCE_01950 8.17e-285 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GPBMILCE_01951 3.36e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
GPBMILCE_01952 4.71e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
GPBMILCE_01953 6.82e-72 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPBMILCE_01955 9.17e-59 - - - - - - - -
GPBMILCE_01956 1.05e-153 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
GPBMILCE_01957 1.52e-43 - - - - - - - -
GPBMILCE_01958 1.63e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPBMILCE_01959 8.42e-237 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
GPBMILCE_01960 7.27e-145 - - - - - - - -
GPBMILCE_01961 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
GPBMILCE_01962 1.11e-224 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPBMILCE_01963 4.4e-112 - - - T - - - Belongs to the universal stress protein A family
GPBMILCE_01964 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
GPBMILCE_01965 1.61e-192 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPBMILCE_01966 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GPBMILCE_01967 1.45e-55 - - - - - - - -
GPBMILCE_01968 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GPBMILCE_01969 2.71e-280 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPBMILCE_01970 4.41e-73 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
GPBMILCE_01971 0.0 - - - EGP - - - Major Facilitator
GPBMILCE_01972 1.25e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
GPBMILCE_01973 4.05e-302 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GPBMILCE_01974 8.28e-135 - - - V - - - VanZ like family
GPBMILCE_01975 7.03e-33 - - - - - - - -
GPBMILCE_01976 5.03e-111 - - - S - - - Short repeat of unknown function (DUF308)
GPBMILCE_01977 3.77e-102 - - - S - - - Psort location Cytoplasmic, score
GPBMILCE_01978 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
GPBMILCE_01979 3.81e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GPBMILCE_01980 7.77e-198 yeaE - - S - - - Aldo keto
GPBMILCE_01981 4.57e-137 - - - M - - - LysM domain protein
GPBMILCE_01982 0.0 - - - EP - - - Psort location Cytoplasmic, score
GPBMILCE_01983 2.73e-148 - - - M - - - LysM domain protein
GPBMILCE_01984 3.48e-192 - - - O - - - Uncharacterized protein family (UPF0051)
GPBMILCE_01985 3.94e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPBMILCE_01986 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
GPBMILCE_01987 1.63e-312 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
GPBMILCE_01988 1.74e-125 - - - K - - - Acetyltransferase (GNAT) domain
GPBMILCE_01996 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GPBMILCE_01997 3.1e-168 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GPBMILCE_01998 8.01e-129 - - - S - - - Protein of unknown function (DUF1700)
GPBMILCE_01999 2.79e-75 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
GPBMILCE_02000 2.94e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GPBMILCE_02002 2.91e-65 - - - - - - - -
GPBMILCE_02004 8.3e-112 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
GPBMILCE_02008 2.01e-13 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPBMILCE_02010 6.56e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GPBMILCE_02011 8.5e-208 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
GPBMILCE_02012 1.53e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GPBMILCE_02013 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GPBMILCE_02014 1.25e-195 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
GPBMILCE_02015 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GPBMILCE_02016 1.13e-264 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
GPBMILCE_02017 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GPBMILCE_02018 6.96e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPBMILCE_02019 9.54e-85 yuxO - - Q - - - Thioesterase superfamily
GPBMILCE_02020 3.51e-142 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
GPBMILCE_02021 1.25e-264 - - - G - - - Transporter, major facilitator family protein
GPBMILCE_02022 1.4e-34 - - - K - - - TRANSCRIPTIONal
GPBMILCE_02023 1.65e-83 yju3 - - I - - - Serine aminopeptidase, S33
GPBMILCE_02024 1.56e-102 pncA - - Q - - - Isochorismatase family
GPBMILCE_02025 6.08e-289 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPBMILCE_02026 1.76e-143 - - - F - - - NUDIX domain
GPBMILCE_02027 2.3e-68 pnb - - C - - - nitroreductase
GPBMILCE_02028 6.92e-96 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
GPBMILCE_02029 1.93e-216 XK27_00915 - - C - - - Luciferase-like monooxygenase
GPBMILCE_02030 7.88e-215 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
GPBMILCE_02031 1.53e-97 - - - S - - - Protein of unknown function (DUF3021)
GPBMILCE_02032 1.05e-102 - - - K - - - LytTr DNA-binding domain
GPBMILCE_02033 2.99e-289 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GPBMILCE_02034 1.09e-250 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GPBMILCE_02035 3.8e-228 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPBMILCE_02036 1.97e-53 - - - S - - - Protein of unknown function (DUF1797)
GPBMILCE_02037 5.85e-128 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPBMILCE_02038 9.64e-141 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GPBMILCE_02039 3.3e-263 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPBMILCE_02040 1.3e-199 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GPBMILCE_02041 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPBMILCE_02043 1.22e-137 - - - L - - - Integrase core domain
GPBMILCE_02044 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GPBMILCE_02045 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPBMILCE_02046 8.1e-281 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GPBMILCE_02047 3.04e-17 - - - - - - - -
GPBMILCE_02048 3.42e-197 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GPBMILCE_02049 1.99e-131 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPBMILCE_02050 1.54e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
GPBMILCE_02051 4.87e-203 - - - - - - - -
GPBMILCE_02052 1.47e-223 - - - - - - - -
GPBMILCE_02053 4.21e-116 - - - S - - - Protein conserved in bacteria
GPBMILCE_02056 7.77e-144 - - - K - - - Transcriptional regulator
GPBMILCE_02057 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GPBMILCE_02058 1.77e-72 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
GPBMILCE_02059 5.07e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GPBMILCE_02060 3.84e-170 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPBMILCE_02061 1.29e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GPBMILCE_02062 1e-146 - - - J - - - 2'-5' RNA ligase superfamily
GPBMILCE_02063 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
GPBMILCE_02064 2.24e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPBMILCE_02065 1.61e-192 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPBMILCE_02066 1.09e-309 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPBMILCE_02067 4.02e-58 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPBMILCE_02068 6.95e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GPBMILCE_02069 1.69e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
GPBMILCE_02070 3.2e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GPBMILCE_02071 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GPBMILCE_02072 9e-72 - - - - - - - -
GPBMILCE_02073 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GPBMILCE_02074 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GPBMILCE_02075 4.44e-273 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPBMILCE_02076 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPBMILCE_02077 8.26e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPBMILCE_02078 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPBMILCE_02079 2.47e-167 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GPBMILCE_02080 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GPBMILCE_02081 9.22e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GPBMILCE_02082 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GPBMILCE_02083 1.91e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GPBMILCE_02084 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GPBMILCE_02085 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
GPBMILCE_02086 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
GPBMILCE_02087 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPBMILCE_02088 2.73e-240 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GPBMILCE_02089 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPBMILCE_02090 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GPBMILCE_02091 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GPBMILCE_02092 8.15e-284 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPBMILCE_02093 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GPBMILCE_02094 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPBMILCE_02095 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GPBMILCE_02096 2.17e-52 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
GPBMILCE_02097 1.53e-118 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPBMILCE_02098 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GPBMILCE_02099 0.0 - - - E ko:K03294 - ko00000 amino acid
GPBMILCE_02100 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GPBMILCE_02101 3.67e-46 - - - - - - - -
GPBMILCE_02102 3.67e-71 - - - S - - - Mazg nucleotide pyrophosphohydrolase
GPBMILCE_02103 1.03e-203 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GPBMILCE_02104 1.55e-109 - - - - - - - -
GPBMILCE_02105 9.73e-146 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
GPBMILCE_02106 1.01e-120 dpsB - - P - - - Belongs to the Dps family
GPBMILCE_02107 1.35e-46 - - - C - - - Heavy-metal-associated domain
GPBMILCE_02108 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
GPBMILCE_02109 6.1e-104 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GPBMILCE_02112 0.0 - - - S - - - Putative peptidoglycan binding domain
GPBMILCE_02113 1.38e-65 - - - - - - - -
GPBMILCE_02114 5.9e-265 isp - - L - - - Transposase
GPBMILCE_02115 1.26e-269 - - - L - - - Integrase core domain
GPBMILCE_02116 4.31e-180 - - - L - - - Bacterial dnaA protein
GPBMILCE_02117 1.42e-27 isp - - L - - - Transposase
GPBMILCE_02118 0.0 - - - L - - - PLD-like domain
GPBMILCE_02120 1.55e-28 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GPBMILCE_02126 4.51e-29 - - - L - - - Addiction module antitoxin, RelB DinJ family
GPBMILCE_02128 1.23e-12 - - - - - - - -
GPBMILCE_02129 2.1e-288 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
GPBMILCE_02130 3.3e-203 - - - J - - - Methyltransferase
GPBMILCE_02131 1.1e-95 - - - - - - - -
GPBMILCE_02132 8.62e-225 - - - - - - - -
GPBMILCE_02133 8.36e-233 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
GPBMILCE_02134 4.01e-216 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPBMILCE_02135 3.35e-59 - - - S - - - Pfam:DUF59
GPBMILCE_02136 4.48e-90 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GPBMILCE_02138 9.72e-135 - - - L - - - Belongs to the 'phage' integrase family
GPBMILCE_02139 4.47e-276 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GPBMILCE_02140 7.84e-116 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
GPBMILCE_02141 5.46e-62 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
GPBMILCE_02142 2.85e-114 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
GPBMILCE_02143 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GPBMILCE_02144 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
GPBMILCE_02145 4.16e-19 - - - - - - - -
GPBMILCE_02146 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GPBMILCE_02147 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GPBMILCE_02148 5.51e-316 steT - - E ko:K03294 - ko00000 amino acid
GPBMILCE_02149 8.05e-208 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GPBMILCE_02150 6.69e-238 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GPBMILCE_02151 1.94e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GPBMILCE_02153 1.83e-21 - - - - - - - -
GPBMILCE_02154 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GPBMILCE_02156 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPBMILCE_02157 1.08e-289 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GPBMILCE_02158 2.51e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPBMILCE_02159 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GPBMILCE_02160 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
GPBMILCE_02161 0.0 eriC - - P ko:K03281 - ko00000 chloride
GPBMILCE_02162 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GPBMILCE_02163 3.29e-187 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
GPBMILCE_02164 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GPBMILCE_02165 3.15e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GPBMILCE_02166 9.61e-137 - - - - - - - -
GPBMILCE_02167 1.84e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPBMILCE_02168 1.38e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
GPBMILCE_02169 6.95e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
GPBMILCE_02170 1.46e-112 - - - K - - - Acetyltransferase (GNAT) domain
GPBMILCE_02171 2.06e-98 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GPBMILCE_02172 3.7e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GPBMILCE_02173 2.76e-215 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
GPBMILCE_02174 1.31e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPBMILCE_02175 1.43e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GPBMILCE_02176 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
GPBMILCE_02177 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPBMILCE_02178 7.48e-165 ybbR - - S - - - YbbR-like protein
GPBMILCE_02179 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPBMILCE_02180 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GPBMILCE_02181 5.17e-70 - - - - - - - -
GPBMILCE_02182 0.0 oatA - - I - - - Acyltransferase
GPBMILCE_02183 3.7e-106 - - - K - - - Transcriptional regulator
GPBMILCE_02184 4.01e-193 - - - S - - - Cof-like hydrolase
GPBMILCE_02185 2.2e-110 lytE - - M - - - Lysin motif
GPBMILCE_02187 2.7e-172 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
GPBMILCE_02188 0.0 yclK - - T - - - Histidine kinase
GPBMILCE_02189 2.71e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
GPBMILCE_02190 6.42e-140 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GPBMILCE_02191 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GPBMILCE_02192 2.49e-39 - - - - - - - -
GPBMILCE_02193 1.99e-33 xylR - - GK - - - ROK family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)