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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
EPNHKGJO_00001	3.52e-106	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
EPNHKGJO_00002	1.18e-104	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EPNHKGJO_00003	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
EPNHKGJO_00004	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
EPNHKGJO_00005	4.36e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EPNHKGJO_00007	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
EPNHKGJO_00008	3.02e-18	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
EPNHKGJO_00013	1.23e-123	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
EPNHKGJO_00021	2.17e-205	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
EPNHKGJO_00026	9.4e-121	-	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EPNHKGJO_00027	1.04e-79	-	-	-	-	-	-	-	-
EPNHKGJO_00028	1.37e-94	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_00029	1.46e-181	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_00030	9.86e-201	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
EPNHKGJO_00031	2.95e-91	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
EPNHKGJO_00032	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EPNHKGJO_00033	4.29e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
EPNHKGJO_00034	1.59e-203	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
EPNHKGJO_00035	4.16e-122	-	-	-	-	-	-	-	-
EPNHKGJO_00036	7.89e-216	-	-	-	-	-	-	-	-
EPNHKGJO_00037	1.34e-126	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
EPNHKGJO_00038	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
EPNHKGJO_00039	7.44e-121	-	-	-	-	-	-	-	-
EPNHKGJO_00040	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
EPNHKGJO_00041	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
EPNHKGJO_00042	1.24e-199	yitS	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_00043	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
EPNHKGJO_00044	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
EPNHKGJO_00045	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
EPNHKGJO_00046	1.92e-08	-	-	-	-	-	-	-	-
EPNHKGJO_00047	2.16e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
EPNHKGJO_00048	5.9e-184	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
EPNHKGJO_00049	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
EPNHKGJO_00050	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
EPNHKGJO_00051	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
EPNHKGJO_00052	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
EPNHKGJO_00053	9.68e-251	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EPNHKGJO_00054	7.1e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EPNHKGJO_00055	7.35e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
EPNHKGJO_00056	1.89e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
EPNHKGJO_00057	2.71e-261	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
EPNHKGJO_00058	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
EPNHKGJO_00059	1.05e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EPNHKGJO_00060	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
EPNHKGJO_00061	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
EPNHKGJO_00062	4.88e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
EPNHKGJO_00063	2.89e-129	yjaV	-	-	-	-	-	-	-
EPNHKGJO_00064	3.7e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
EPNHKGJO_00065	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
EPNHKGJO_00066	2.67e-38	yjzB	-	-	-	-	-	-	-
EPNHKGJO_00067	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPNHKGJO_00068	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EPNHKGJO_00069	5.27e-190	yjaZ	-	-	O	-	-	-	Zn-dependent protease
EPNHKGJO_00070	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPNHKGJO_00071	1.99e-235	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPNHKGJO_00072	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
EPNHKGJO_00073	1.58e-214	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPNHKGJO_00074	1.22e-196	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPNHKGJO_00075	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
EPNHKGJO_00076	2.92e-233	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
EPNHKGJO_00077	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
EPNHKGJO_00078	1.2e-211	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPNHKGJO_00079	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPNHKGJO_00080	3.22e-248	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPNHKGJO_00081	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPNHKGJO_00082	1.85e-257	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
EPNHKGJO_00083	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPNHKGJO_00084	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EPNHKGJO_00085	2.89e-143	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
EPNHKGJO_00086	3.98e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EPNHKGJO_00087	3.45e-279	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
EPNHKGJO_00088	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
EPNHKGJO_00089	2.68e-28	-	-	-	-	-	-	-	-
EPNHKGJO_00090	1.54e-217	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
EPNHKGJO_00091	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
EPNHKGJO_00092	2.07e-128	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EPNHKGJO_00093	7.32e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_00094	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
EPNHKGJO_00095	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
EPNHKGJO_00096	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPNHKGJO_00097	2.12e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
EPNHKGJO_00098	6.65e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EPNHKGJO_00099	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EPNHKGJO_00100	7.78e-175	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EPNHKGJO_00101	5.7e-139	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
EPNHKGJO_00102	1.09e-275	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
EPNHKGJO_00103	2.18e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
EPNHKGJO_00104	6.78e-174	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EPNHKGJO_00105	2.52e-237	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EPNHKGJO_00106	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
EPNHKGJO_00107	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
EPNHKGJO_00108	2.56e-104	yjbX	-	-	S	-	-	-	Spore coat protein
EPNHKGJO_00109	4.57e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
EPNHKGJO_00110	3.12e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
EPNHKGJO_00111	3.55e-110	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
EPNHKGJO_00112	9.52e-51	cotW	-	-	-	ko:K06341	-	ko00000	-
EPNHKGJO_00113	1.44e-72	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
EPNHKGJO_00114	5.03e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
EPNHKGJO_00117	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
EPNHKGJO_00118	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
EPNHKGJO_00119	6.31e-51	-	-	-	-	-	-	-	-
EPNHKGJO_00120	1.1e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPNHKGJO_00121	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
EPNHKGJO_00122	1.91e-177	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
EPNHKGJO_00123	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
EPNHKGJO_00124	1.84e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
EPNHKGJO_00126	2.35e-295	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
EPNHKGJO_00128	3.72e-38	-	-	-	-	-	-	-	-
EPNHKGJO_00129	4.41e-24	-	-	-	-	-	-	-	-
EPNHKGJO_00131	6.07e-273	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
EPNHKGJO_00132	6.86e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
EPNHKGJO_00133	2.02e-78	yttA	-	-	S	-	-	-	Pfam Transposase IS66
EPNHKGJO_00134	2.45e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
EPNHKGJO_00135	6.61e-184	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EPNHKGJO_00136	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
EPNHKGJO_00137	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
EPNHKGJO_00138	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
EPNHKGJO_00139	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
EPNHKGJO_00140	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
EPNHKGJO_00141	1.66e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPNHKGJO_00142	3.14e-313	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
EPNHKGJO_00143	2.08e-240	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_00144	3.38e-221	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
EPNHKGJO_00145	4.34e-177	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EPNHKGJO_00146	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EPNHKGJO_00147	5.21e-275	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EPNHKGJO_00148	6.59e-160	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EPNHKGJO_00149	1.86e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EPNHKGJO_00150	1.91e-280	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
EPNHKGJO_00151	3.67e-177	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
EPNHKGJO_00152	6.19e-193	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
EPNHKGJO_00153	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
EPNHKGJO_00154	1.13e-165	ytdP	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00155	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00156	2.27e-82	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
EPNHKGJO_00157	3.17e-122	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
EPNHKGJO_00158	4.8e-278	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
EPNHKGJO_00159	2.27e-92	yteS	-	-	G	-	-	-	transport
EPNHKGJO_00160	1.87e-240	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
EPNHKGJO_00161	8.22e-99	yteU	-	-	S	-	-	-	Integral membrane protein
EPNHKGJO_00162	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
EPNHKGJO_00163	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
EPNHKGJO_00164	1.16e-292	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
EPNHKGJO_00165	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPNHKGJO_00166	7.43e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
EPNHKGJO_00167	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
EPNHKGJO_00168	5.66e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EPNHKGJO_00169	4.28e-256	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
EPNHKGJO_00170	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
EPNHKGJO_00171	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
EPNHKGJO_00172	6.05e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
EPNHKGJO_00173	1.5e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EPNHKGJO_00174	9.92e-212	ytlQ	-	-	-	-	-	-	-
EPNHKGJO_00175	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
EPNHKGJO_00176	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
EPNHKGJO_00177	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
EPNHKGJO_00178	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
EPNHKGJO_00179	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EPNHKGJO_00180	1.06e-190	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
EPNHKGJO_00181	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
EPNHKGJO_00182	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
EPNHKGJO_00183	3.56e-259	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
EPNHKGJO_00184	4.88e-29	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
EPNHKGJO_00185	4.89e-63	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
EPNHKGJO_00186	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
EPNHKGJO_00187	1.1e-190	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
EPNHKGJO_00188	7.25e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPNHKGJO_00189	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
EPNHKGJO_00190	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
EPNHKGJO_00191	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EPNHKGJO_00192	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
EPNHKGJO_00193	2.23e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
EPNHKGJO_00194	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EPNHKGJO_00195	1.7e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
EPNHKGJO_00196	6.84e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
EPNHKGJO_00197	1.31e-160	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
EPNHKGJO_00198	2.65e-292	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
EPNHKGJO_00199	1.77e-151	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
EPNHKGJO_00200	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EPNHKGJO_00201	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EPNHKGJO_00202	2.16e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPNHKGJO_00204	4.73e-306	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EPNHKGJO_00205	2.29e-29	ywtC	-	-	-	-	-	-	-
EPNHKGJO_00206	3.66e-275	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EPNHKGJO_00207	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
EPNHKGJO_00208	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
EPNHKGJO_00209	9.35e-228	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
EPNHKGJO_00210	1.07e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPNHKGJO_00211	4.61e-84	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EPNHKGJO_00212	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EPNHKGJO_00213	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
EPNHKGJO_00214	9.04e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
EPNHKGJO_00215	1.14e-118	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
EPNHKGJO_00216	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
EPNHKGJO_00217	1.45e-124	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
EPNHKGJO_00218	6.15e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
EPNHKGJO_00219	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
EPNHKGJO_00220	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
EPNHKGJO_00221	1.79e-227	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EPNHKGJO_00222	1.06e-162	ywrJ	-	-	-	-	-	-	-
EPNHKGJO_00223	4.21e-112	cotB	-	-	-	ko:K06325	-	ko00000	-
EPNHKGJO_00224	3.12e-29	cotB	-	-	-	ko:K06325	-	ko00000	-
EPNHKGJO_00225	1.2e-264	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
EPNHKGJO_00226	5.01e-18	-	-	-	-	-	-	-	-
EPNHKGJO_00227	3.43e-140	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EPNHKGJO_00228	3.8e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
EPNHKGJO_00229	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
EPNHKGJO_00230	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
EPNHKGJO_00231	4.53e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
EPNHKGJO_00232	2.47e-113	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
EPNHKGJO_00234	5.23e-130	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
EPNHKGJO_00235	4.73e-209	-	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00236	1.77e-149	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EPNHKGJO_00238	3.64e-98	ywqJ	-	-	S	-	-	-	Pre-toxin TG
EPNHKGJO_00239	1.3e-23	-	-	-	-	-	-	-	-
EPNHKGJO_00240	1.77e-26	-	-	-	-	-	-	-	-
EPNHKGJO_00241	1.27e-264	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
EPNHKGJO_00242	2.47e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
EPNHKGJO_00244	3.44e-195	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
EPNHKGJO_00245	5.43e-312	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EPNHKGJO_00246	1.75e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
EPNHKGJO_00247	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
EPNHKGJO_00248	2.17e-162	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
EPNHKGJO_00249	3.6e-25	-	-	-	-	-	-	-	-
EPNHKGJO_00250	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
EPNHKGJO_00251	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
EPNHKGJO_00252	1.45e-199	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
EPNHKGJO_00253	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
EPNHKGJO_00254	1.04e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
EPNHKGJO_00255	3.56e-86	ywpG	-	-	-	-	-	-	-
EPNHKGJO_00256	3.59e-88	ywpF	-	-	S	-	-	-	YwpF-like protein
EPNHKGJO_00257	6.34e-66	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
EPNHKGJO_00258	9.97e-197	ywpD	-	-	T	-	-	-	Histidine kinase
EPNHKGJO_00259	1.61e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EPNHKGJO_00260	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EPNHKGJO_00261	4.47e-256	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
EPNHKGJO_00262	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
EPNHKGJO_00263	6.18e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
EPNHKGJO_00264	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
EPNHKGJO_00265	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
EPNHKGJO_00266	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
EPNHKGJO_00267	3.92e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_00268	1.54e-307	ywoF	-	-	P	-	-	-	Right handed beta helix region
EPNHKGJO_00269	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
EPNHKGJO_00270	3.63e-305	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
EPNHKGJO_00271	2.11e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
EPNHKGJO_00272	9.77e-101	-	-	-	-	-	-	-	-
EPNHKGJO_00273	1.6e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
EPNHKGJO_00274	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
EPNHKGJO_00275	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
EPNHKGJO_00276	2.7e-94	ywnJ	-	-	S	-	-	-	VanZ like family
EPNHKGJO_00277	1.07e-160	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
EPNHKGJO_00278	6.07e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
EPNHKGJO_00279	3.99e-17	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
EPNHKGJO_00280	2.37e-90	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
EPNHKGJO_00281	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPNHKGJO_00282	8.04e-183	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
EPNHKGJO_00283	1.24e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
EPNHKGJO_00284	3.27e-142	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
EPNHKGJO_00285	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00286	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EPNHKGJO_00287	1.78e-80	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
EPNHKGJO_00288	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
EPNHKGJO_00289	1.1e-143	-	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
EPNHKGJO_00290	9.77e-155	-	-	-	S	ko:K11962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPNHKGJO_00291	3.8e-233	-	-	-	E	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
EPNHKGJO_00292	3.05e-188	-	-	-	E	ko:K11960	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
EPNHKGJO_00293	8.55e-281	-	-	-	E	ko:K11959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
EPNHKGJO_00294	6.16e-19	csbD	-	-	K	-	-	-	CsbD-like
EPNHKGJO_00295	3.22e-109	ywmF	-	-	S	-	-	-	Peptidase M50
EPNHKGJO_00296	6.22e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
EPNHKGJO_00297	1.08e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EPNHKGJO_00298	3.69e-186	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EPNHKGJO_00300	5.87e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
EPNHKGJO_00301	1.28e-155	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
EPNHKGJO_00302	3.05e-237	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
EPNHKGJO_00303	2.02e-305	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPNHKGJO_00304	3.81e-171	ywmB	-	-	S	-	-	-	TATA-box binding
EPNHKGJO_00305	4.54e-45	ywzB	-	-	S	-	-	-	membrane
EPNHKGJO_00306	7.16e-114	ywmA	-	-	-	-	-	-	-
EPNHKGJO_00307	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
EPNHKGJO_00308	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EPNHKGJO_00309	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EPNHKGJO_00310	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EPNHKGJO_00311	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPNHKGJO_00312	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EPNHKGJO_00313	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPNHKGJO_00314	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
EPNHKGJO_00315	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
EPNHKGJO_00316	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EPNHKGJO_00317	1.78e-302	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPNHKGJO_00318	7.13e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
EPNHKGJO_00319	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
EPNHKGJO_00320	1.11e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPNHKGJO_00321	1.86e-116	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
EPNHKGJO_00322	6.77e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EPNHKGJO_00323	2.55e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
EPNHKGJO_00324	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
EPNHKGJO_00325	9.69e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
EPNHKGJO_00327	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EPNHKGJO_00328	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EPNHKGJO_00329	3.69e-84	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPNHKGJO_00330	3.33e-114	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EPNHKGJO_00331	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
EPNHKGJO_00332	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
EPNHKGJO_00333	4.06e-134	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
EPNHKGJO_00334	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
EPNHKGJO_00335	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EPNHKGJO_00336	3.51e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
EPNHKGJO_00337	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPNHKGJO_00338	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EPNHKGJO_00339	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
EPNHKGJO_00340	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
EPNHKGJO_00341	9.11e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
EPNHKGJO_00342	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EPNHKGJO_00343	8.03e-81	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EPNHKGJO_00344	2.01e-267	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
EPNHKGJO_00345	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
EPNHKGJO_00346	4.55e-285	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EPNHKGJO_00347	1.99e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EPNHKGJO_00348	1.32e-57	ywjC	-	-	-	-	-	-	-
EPNHKGJO_00349	1.51e-121	ywjB	-	-	H	-	-	-	RibD C-terminal domain
EPNHKGJO_00350	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
EPNHKGJO_00351	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPNHKGJO_00352	3.42e-158	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
EPNHKGJO_00353	7.94e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
EPNHKGJO_00354	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
EPNHKGJO_00355	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPNHKGJO_00356	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
EPNHKGJO_00357	1.51e-178	ywiC	-	-	S	-	-	-	YwiC-like protein
EPNHKGJO_00358	2.3e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
EPNHKGJO_00359	8.44e-274	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
EPNHKGJO_00360	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
EPNHKGJO_00361	6.59e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_00362	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
EPNHKGJO_00363	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
EPNHKGJO_00365	1.5e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EPNHKGJO_00366	4.86e-297	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
EPNHKGJO_00367	5.69e-275	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
EPNHKGJO_00368	2.34e-315	-	-	-	L	-	-	-	Peptidase, M16
EPNHKGJO_00370	2.83e-215	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
EPNHKGJO_00371	3.78e-68	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
EPNHKGJO_00372	2.29e-153	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
EPNHKGJO_00373	5.96e-98	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
EPNHKGJO_00374	4.64e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
EPNHKGJO_00376	7.29e-219	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
EPNHKGJO_00377	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
EPNHKGJO_00378	1.47e-100	-	-	-	K	-	-	-	acetyltransferase
EPNHKGJO_00379	4.86e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
EPNHKGJO_00380	4.39e-304	yhfN	-	-	O	-	-	-	Peptidase M48
EPNHKGJO_00381	7.65e-83	yhfM	-	-	-	-	-	-	-
EPNHKGJO_00382	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
EPNHKGJO_00383	2.13e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
EPNHKGJO_00384	8.2e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
EPNHKGJO_00385	4.01e-181	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EPNHKGJO_00386	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPNHKGJO_00387	1.53e-93	-	-	-	S	-	-	-	ASCH
EPNHKGJO_00388	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
EPNHKGJO_00389	1.88e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
EPNHKGJO_00390	2.07e-235	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPNHKGJO_00391	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
EPNHKGJO_00392	7.9e-130	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_00393	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EPNHKGJO_00394	3.41e-231	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
EPNHKGJO_00395	3.17e-260	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EPNHKGJO_00396	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
EPNHKGJO_00397	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
EPNHKGJO_00398	8.58e-46	-	-	-	C	-	-	-	Rubrerythrin
EPNHKGJO_00399	3.29e-313	yhfA	-	-	C	-	-	-	membrane
EPNHKGJO_00400	1.32e-292	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EPNHKGJO_00401	7.1e-162	ecsC	-	-	S	-	-	-	EcsC protein family
EPNHKGJO_00402	5.15e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
EPNHKGJO_00403	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
EPNHKGJO_00404	1.43e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EPNHKGJO_00405	2.15e-261	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EPNHKGJO_00406	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
EPNHKGJO_00407	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
EPNHKGJO_00408	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
EPNHKGJO_00409	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
EPNHKGJO_00410	1.4e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
EPNHKGJO_00411	5.15e-176	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EPNHKGJO_00412	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
EPNHKGJO_00413	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
EPNHKGJO_00414	0.0	yhaN	-	-	L	-	-	-	AAA domain
EPNHKGJO_00415	6.11e-297	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
EPNHKGJO_00416	1.72e-270	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
EPNHKGJO_00417	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_00418	9.36e-36	-	-	-	S	-	-	-	YhzD-like protein
EPNHKGJO_00419	3.62e-169	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
EPNHKGJO_00421	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
EPNHKGJO_00422	1.77e-265	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
EPNHKGJO_00423	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
EPNHKGJO_00424	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
EPNHKGJO_00425	9.07e-68	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
EPNHKGJO_00426	5.22e-167	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
EPNHKGJO_00427	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
EPNHKGJO_00428	2.93e-259	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
EPNHKGJO_00429	3.37e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
EPNHKGJO_00430	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
EPNHKGJO_00431	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
EPNHKGJO_00432	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
EPNHKGJO_00433	1.51e-139	yheG	-	-	GM	-	-	-	NAD(P)H-binding
EPNHKGJO_00434	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
EPNHKGJO_00435	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
EPNHKGJO_00436	1.86e-109	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
EPNHKGJO_00437	1.03e-302	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
EPNHKGJO_00438	3.16e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EPNHKGJO_00439	2.14e-195	nodB1	-	-	G	-	-	-	deacetylase
EPNHKGJO_00440	1.19e-179	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EPNHKGJO_00441	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
EPNHKGJO_00442	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
EPNHKGJO_00443	1.5e-171	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
EPNHKGJO_00444	2.78e-85	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPNHKGJO_00445	5.01e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPNHKGJO_00446	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
EPNHKGJO_00447	8.45e-283	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
EPNHKGJO_00448	4.07e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
EPNHKGJO_00449	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
EPNHKGJO_00450	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EPNHKGJO_00451	3.9e-243	yhdN	-	-	C	-	-	-	Aldo keto reductase
EPNHKGJO_00452	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPNHKGJO_00453	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
EPNHKGJO_00454	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
EPNHKGJO_00455	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPNHKGJO_00456	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPNHKGJO_00457	5e-309	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EPNHKGJO_00458	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
EPNHKGJO_00459	5.51e-206	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_00460	1.51e-260	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
EPNHKGJO_00461	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_00462	1.05e-199	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
EPNHKGJO_00463	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
EPNHKGJO_00464	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
EPNHKGJO_00465	1.02e-304	ygxB	-	-	M	-	-	-	Conserved TM helix
EPNHKGJO_00466	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
EPNHKGJO_00467	4.06e-271	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
EPNHKGJO_00468	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
EPNHKGJO_00469	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
EPNHKGJO_00470	1.9e-115	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
EPNHKGJO_00471	5.67e-146	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPNHKGJO_00472	1.54e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_00473	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
EPNHKGJO_00474	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EPNHKGJO_00475	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EPNHKGJO_00476	1.1e-193	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EPNHKGJO_00477	4.4e-134	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EPNHKGJO_00478	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPNHKGJO_00479	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EPNHKGJO_00480	1.24e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
EPNHKGJO_00481	7.16e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
EPNHKGJO_00482	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
EPNHKGJO_00483	8.26e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
EPNHKGJO_00484	4.89e-132	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
EPNHKGJO_00485	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
EPNHKGJO_00486	9.06e-142	yhcQ	-	-	M	-	-	-	Spore coat protein
EPNHKGJO_00487	1.18e-216	yhcP	-	-	-	-	-	-	-
EPNHKGJO_00488	1.9e-95	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPNHKGJO_00489	2.4e-72	yhcM	-	-	-	-	-	-	-
EPNHKGJO_00490	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPNHKGJO_00491	4.78e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
EPNHKGJO_00492	4.31e-192	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
EPNHKGJO_00493	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
EPNHKGJO_00494	2.83e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EPNHKGJO_00495	5.09e-210	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_00496	1.32e-155	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_00497	5.59e-78	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_00498	2.48e-65	-	-	-	-	-	-	-	-
EPNHKGJO_00499	3.95e-59	yhcC	-	-	-	-	-	-	-
EPNHKGJO_00500	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
EPNHKGJO_00501	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
EPNHKGJO_00502	6.29e-132	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
EPNHKGJO_00503	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
EPNHKGJO_00504	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
EPNHKGJO_00505	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
EPNHKGJO_00506	5.32e-83	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
EPNHKGJO_00507	3.73e-133	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
EPNHKGJO_00508	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EPNHKGJO_00509	4.41e-222	yhbB	-	-	S	-	-	-	Putative amidase domain
EPNHKGJO_00510	4.88e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EPNHKGJO_00511	1.92e-147	yhzB	-	-	S	-	-	-	B3/4 domain
EPNHKGJO_00513	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_00514	5.41e-100	ygaO	-	-	-	-	-	-	-
EPNHKGJO_00515	1.96e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPNHKGJO_00517	3.13e-274	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
EPNHKGJO_00518	2.66e-123	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EPNHKGJO_00519	4.95e-49	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EPNHKGJO_00520	2.08e-218	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
EPNHKGJO_00521	3.67e-178	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EPNHKGJO_00522	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
EPNHKGJO_00524	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
EPNHKGJO_00525	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EPNHKGJO_00526	5.27e-168	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
EPNHKGJO_00527	1.58e-36	-	-	-	-	-	-	-	-
EPNHKGJO_00528	1.5e-183	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
EPNHKGJO_00529	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
EPNHKGJO_00530	1.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
EPNHKGJO_00531	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
EPNHKGJO_00532	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPNHKGJO_00533	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
EPNHKGJO_00534	3.95e-113	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
EPNHKGJO_00536	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EPNHKGJO_00537	1.73e-252	yubA	-	-	S	-	-	-	transporter activity
EPNHKGJO_00538	3.71e-235	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
EPNHKGJO_00539	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
EPNHKGJO_00540	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
EPNHKGJO_00541	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
EPNHKGJO_00542	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
EPNHKGJO_00543	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
EPNHKGJO_00544	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
EPNHKGJO_00545	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
EPNHKGJO_00546	5.31e-291	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
EPNHKGJO_00547	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
EPNHKGJO_00548	2.51e-180	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
EPNHKGJO_00549	5e-48	-	-	-	-	-	-	-	-
EPNHKGJO_00550	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
EPNHKGJO_00551	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
EPNHKGJO_00552	1.03e-299	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
EPNHKGJO_00553	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
EPNHKGJO_00554	2.16e-48	-	-	-	-	-	-	-	-
EPNHKGJO_00555	1.01e-68	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
EPNHKGJO_00556	2.06e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
EPNHKGJO_00557	1.42e-93	yugN	-	-	S	-	-	-	YugN-like family
EPNHKGJO_00559	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
EPNHKGJO_00560	3.22e-290	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
EPNHKGJO_00561	6.7e-286	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
EPNHKGJO_00562	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
EPNHKGJO_00563	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
EPNHKGJO_00564	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
EPNHKGJO_00565	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00566	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
EPNHKGJO_00567	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
EPNHKGJO_00568	1.16e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EPNHKGJO_00569	6.13e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_00570	4.84e-89	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
EPNHKGJO_00571	1.41e-148	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
EPNHKGJO_00573	3.79e-243	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
EPNHKGJO_00574	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
EPNHKGJO_00575	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_00576	1.2e-112	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
EPNHKGJO_00577	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
EPNHKGJO_00578	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
EPNHKGJO_00579	5e-253	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
EPNHKGJO_00580	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_00581	2.6e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
EPNHKGJO_00582	4.9e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
EPNHKGJO_00583	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
EPNHKGJO_00584	1.73e-22	-	-	-	-	-	-	-	-
EPNHKGJO_00585	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EPNHKGJO_00586	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPNHKGJO_00587	3.48e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPNHKGJO_00588	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPNHKGJO_00589	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPNHKGJO_00590	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPNHKGJO_00591	6.98e-78	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
EPNHKGJO_00592	7.81e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
EPNHKGJO_00593	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPNHKGJO_00594	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_00596	3.33e-168	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
EPNHKGJO_00597	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
EPNHKGJO_00598	8.73e-09	yuzC	-	-	-	-	-	-	-
EPNHKGJO_00599	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
EPNHKGJO_00600	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPNHKGJO_00601	3.82e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
EPNHKGJO_00602	5.37e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
EPNHKGJO_00603	1.34e-51	yueH	-	-	S	-	-	-	YueH-like protein
EPNHKGJO_00604	1.19e-41	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
EPNHKGJO_00605	6.42e-243	yueF	-	-	S	-	-	-	transporter activity
EPNHKGJO_00606	1.01e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
EPNHKGJO_00607	3.85e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
EPNHKGJO_00608	2.35e-54	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_00609	1.47e-74	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_00610	4.37e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
EPNHKGJO_00611	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
EPNHKGJO_00612	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EPNHKGJO_00613	5.18e-270	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
EPNHKGJO_00614	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
EPNHKGJO_00615	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
EPNHKGJO_00616	4.03e-290	yukF	-	-	QT	-	-	-	Transcriptional regulator
EPNHKGJO_00617	5.47e-260	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
EPNHKGJO_00618	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
EPNHKGJO_00619	1.66e-46	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
EPNHKGJO_00620	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPNHKGJO_00621	3.15e-228	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
EPNHKGJO_00622	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
EPNHKGJO_00623	3.34e-287	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
EPNHKGJO_00624	1.95e-176	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNHKGJO_00625	8.94e-213	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
EPNHKGJO_00626	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
EPNHKGJO_00627	1.38e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
EPNHKGJO_00628	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
EPNHKGJO_00629	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EPNHKGJO_00630	7.09e-101	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
EPNHKGJO_00631	6.61e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_00632	1.97e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
EPNHKGJO_00633	6.9e-300	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
EPNHKGJO_00634	5.51e-239	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
EPNHKGJO_00636	1.29e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EPNHKGJO_00637	2.25e-115	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
EPNHKGJO_00638	1.64e-86	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPNHKGJO_00639	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
EPNHKGJO_00640	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EPNHKGJO_00641	2.97e-268	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPNHKGJO_00642	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
EPNHKGJO_00643	9.17e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
EPNHKGJO_00644	5.44e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_00645	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
EPNHKGJO_00646	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
EPNHKGJO_00647	2.99e-220	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EPNHKGJO_00648	5.64e-252	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EPNHKGJO_00649	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
EPNHKGJO_00650	8.97e-253	yutH	-	-	S	-	-	-	Spore coat protein
EPNHKGJO_00651	3.34e-112	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
EPNHKGJO_00652	3.03e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EPNHKGJO_00653	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
EPNHKGJO_00654	2.17e-61	yutD	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_00655	2.71e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPNHKGJO_00656	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EPNHKGJO_00657	7.63e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
EPNHKGJO_00658	2.54e-168	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
EPNHKGJO_00659	1.33e-59	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
EPNHKGJO_00660	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
EPNHKGJO_00661	2.65e-180	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EPNHKGJO_00662	1.73e-219	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
EPNHKGJO_00663	1.85e-61	yunG	-	-	-	-	-	-	-
EPNHKGJO_00664	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EPNHKGJO_00665	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
EPNHKGJO_00666	1.99e-298	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
EPNHKGJO_00667	1.76e-280	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
EPNHKGJO_00668	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
EPNHKGJO_00669	1.21e-71	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
EPNHKGJO_00670	0.000154	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
EPNHKGJO_00671	1.99e-121	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EPNHKGJO_00672	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EPNHKGJO_00673	4.27e-188	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EPNHKGJO_00674	3.58e-142	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
EPNHKGJO_00675	3.18e-237	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EPNHKGJO_00676	3.32e-303	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EPNHKGJO_00677	1.68e-294	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EPNHKGJO_00678	2.1e-214	bsn	-	-	L	-	-	-	Ribonuclease
EPNHKGJO_00679	1.91e-30	-	-	-	S	-	-	-	branched-chain amino acid
EPNHKGJO_00680	1.3e-93	-	-	-	E	-	-	-	AzlC protein
EPNHKGJO_00681	8.01e-198	gntR9	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPNHKGJO_00682	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
EPNHKGJO_00683	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
EPNHKGJO_00684	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EPNHKGJO_00685	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EPNHKGJO_00686	4.18e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
EPNHKGJO_00687	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
EPNHKGJO_00688	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPNHKGJO_00690	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
EPNHKGJO_00691	5.03e-278	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
EPNHKGJO_00692	9.32e-70	ydbL	-	-	-	-	-	-	-
EPNHKGJO_00693	8.57e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EPNHKGJO_00694	5.36e-218	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_00695	5.38e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
EPNHKGJO_00696	5.16e-289	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPNHKGJO_00697	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
EPNHKGJO_00698	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
EPNHKGJO_00699	4.99e-251	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EPNHKGJO_00700	2.74e-176	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
EPNHKGJO_00701	1.49e-81	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
EPNHKGJO_00702	3.09e-78	ydbB	-	-	G	-	-	-	Cupin domain
EPNHKGJO_00703	1.83e-09	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
EPNHKGJO_00704	4.3e-190	ydbA	-	-	P	-	-	-	EcsC protein family
EPNHKGJO_00705	4.22e-99	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
EPNHKGJO_00706	1.67e-42	ydaS	-	-	S	-	-	-	membrane
EPNHKGJO_00707	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
EPNHKGJO_00708	8.72e-53	-	-	-	-	-	-	-	-
EPNHKGJO_00709	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
EPNHKGJO_00710	4.05e-98	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
EPNHKGJO_00711	0.0	ydaO	-	-	E	-	-	-	amino acid
EPNHKGJO_00712	7.26e-237	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
EPNHKGJO_00713	7.66e-234	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
EPNHKGJO_00714	1.93e-304	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
EPNHKGJO_00715	4.3e-221	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
EPNHKGJO_00716	2.78e-164	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
EPNHKGJO_00717	7.07e-115	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
EPNHKGJO_00718	1.47e-265	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EPNHKGJO_00719	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPNHKGJO_00720	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
EPNHKGJO_00721	5.19e-60	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
EPNHKGJO_00722	2.18e-177	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EPNHKGJO_00723	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
EPNHKGJO_00724	8.32e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EPNHKGJO_00725	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
EPNHKGJO_00726	4.37e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_00727	2.76e-125	ydaC	-	-	Q	-	-	-	Methyltransferase domain
EPNHKGJO_00728	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
EPNHKGJO_00729	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
EPNHKGJO_00730	8.25e-218	ycsN	-	-	S	-	-	-	Oxidoreductase
EPNHKGJO_00731	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
EPNHKGJO_00732	2.33e-08	yczJ	-	-	S	-	-	-	biosynthesis
EPNHKGJO_00733	3.25e-43	yczJ	-	-	S	-	-	-	biosynthesis
EPNHKGJO_00735	6.94e-153	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
EPNHKGJO_00736	6.3e-170	kipR	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00737	9.08e-235	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
EPNHKGJO_00738	1.19e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
EPNHKGJO_00739	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
EPNHKGJO_00740	2.78e-273	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
EPNHKGJO_00741	3.82e-181	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
EPNHKGJO_00742	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
EPNHKGJO_00744	3.88e-140	yvgT	-	-	S	-	-	-	membrane
EPNHKGJO_00745	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
EPNHKGJO_00746	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EPNHKGJO_00747	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EPNHKGJO_00748	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
EPNHKGJO_00749	7.97e-113	yvgO	-	-	-	-	-	-	-
EPNHKGJO_00750	2.52e-200	yvgN	-	-	S	-	-	-	reductase
EPNHKGJO_00751	7.09e-153	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
EPNHKGJO_00752	8.94e-177	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
EPNHKGJO_00753	4.91e-212	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
EPNHKGJO_00754	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
EPNHKGJO_00755	6.83e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
EPNHKGJO_00756	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
EPNHKGJO_00757	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
EPNHKGJO_00758	4.45e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPNHKGJO_00759	2.72e-233	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_00760	6.5e-224	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_00761	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
EPNHKGJO_00762	8.47e-230	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
EPNHKGJO_00763	4.64e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_00764	8.98e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
EPNHKGJO_00765	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
EPNHKGJO_00766	2.17e-290	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
EPNHKGJO_00767	6.98e-26	-	-	-	S	-	-	-	YvrJ protein family
EPNHKGJO_00768	4.55e-124	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
EPNHKGJO_00769	5.07e-32	-	-	-	-	-	-	-	-
EPNHKGJO_00770	3.16e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_00771	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
EPNHKGJO_00772	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
EPNHKGJO_00773	1.18e-178	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNHKGJO_00774	2.98e-218	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
EPNHKGJO_00775	1.56e-235	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_00776	7.72e-311	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EPNHKGJO_00777	5.32e-129	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
EPNHKGJO_00778	4.58e-288	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_00779	1.07e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
EPNHKGJO_00780	3.49e-58	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EPNHKGJO_00781	3.17e-39	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EPNHKGJO_00782	6.72e-173	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
EPNHKGJO_00783	7.65e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
EPNHKGJO_00784	2.35e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_00785	8.64e-137	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPNHKGJO_00786	2.5e-242	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
EPNHKGJO_00787	1.13e-250	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
EPNHKGJO_00788	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
EPNHKGJO_00789	2.6e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
EPNHKGJO_00790	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EPNHKGJO_00791	5.07e-203	yuxN	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00792	9.22e-317	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_00793	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_00794	3.08e-302	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPNHKGJO_00795	2.15e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
EPNHKGJO_00796	3.16e-196	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNHKGJO_00797	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
EPNHKGJO_00798	4.94e-88	-	-	-	S	-	-	-	YusW-like protein
EPNHKGJO_00799	1.06e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
EPNHKGJO_00800	1.05e-63	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
EPNHKGJO_00801	1.98e-202	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
EPNHKGJO_00802	2.87e-137	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNHKGJO_00803	2.82e-83	yusQ	-	-	S	-	-	-	Tautomerase enzyme
EPNHKGJO_00804	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
EPNHKGJO_00805	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
EPNHKGJO_00806	2.29e-69	yusN	-	-	M	-	-	-	Coat F domain
EPNHKGJO_00807	2.23e-54	-	-	-	-	-	-	-	-
EPNHKGJO_00808	8.15e-210	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
EPNHKGJO_00809	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
EPNHKGJO_00810	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
EPNHKGJO_00811	7.74e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
EPNHKGJO_00812	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
EPNHKGJO_00813	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
EPNHKGJO_00814	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EPNHKGJO_00815	2.11e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
EPNHKGJO_00816	8.9e-96	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
EPNHKGJO_00817	8.14e-73	yusE	-	-	CO	-	-	-	Thioredoxin
EPNHKGJO_00818	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
EPNHKGJO_00819	2.5e-235	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPNHKGJO_00820	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
EPNHKGJO_00821	7.98e-187	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
EPNHKGJO_00822	3.06e-60	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EPNHKGJO_00823	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EPNHKGJO_00824	6.1e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
EPNHKGJO_00825	1.63e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPNHKGJO_00826	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
EPNHKGJO_00827	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
EPNHKGJO_00828	1.25e-56	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
EPNHKGJO_00829	5.06e-86	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPNHKGJO_00830	3.35e-226	-	-	-	L	-	-	-	Replication protein
EPNHKGJO_00832	2.95e-42	-	-	-	-	-	-	-	-
EPNHKGJO_00835	2.31e-65	XK26_06135	-	-	D	-	-	-	plasmid recombination enzyme
EPNHKGJO_00837	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EPNHKGJO_00838	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EPNHKGJO_00839	6.43e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
EPNHKGJO_00840	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
EPNHKGJO_00841	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EPNHKGJO_00842	1.97e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
EPNHKGJO_00843	4.3e-259	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
EPNHKGJO_00844	2.04e-275	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
EPNHKGJO_00845	9.85e-263	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
EPNHKGJO_00847	8.18e-289	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
EPNHKGJO_00848	8.31e-226	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
EPNHKGJO_00849	1.67e-309	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EPNHKGJO_00850	2.32e-194	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
EPNHKGJO_00851	5.02e-168	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
EPNHKGJO_00852	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
EPNHKGJO_00853	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EPNHKGJO_00854	4.49e-193	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EPNHKGJO_00855	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EPNHKGJO_00856	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EPNHKGJO_00857	7.07e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EPNHKGJO_00858	3.23e-218	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
EPNHKGJO_00859	1.5e-179	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EPNHKGJO_00860	8.31e-293	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EPNHKGJO_00861	3.22e-192	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
EPNHKGJO_00862	9.9e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
EPNHKGJO_00863	9.47e-238	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EPNHKGJO_00864	6.19e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
EPNHKGJO_00865	1.44e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
EPNHKGJO_00866	1.27e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
EPNHKGJO_00867	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EPNHKGJO_00868	4.78e-95	ytkA	-	-	S	-	-	-	YtkA-like
EPNHKGJO_00870	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
EPNHKGJO_00871	1.52e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
EPNHKGJO_00872	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
EPNHKGJO_00873	1.09e-182	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EPNHKGJO_00874	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
EPNHKGJO_00875	1.08e-239	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EPNHKGJO_00876	1.06e-187	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EPNHKGJO_00877	1.16e-51	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
EPNHKGJO_00878	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EPNHKGJO_00879	3.07e-284	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EPNHKGJO_00880	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
EPNHKGJO_00881	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
EPNHKGJO_00882	2.39e-87	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EPNHKGJO_00883	6.67e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
EPNHKGJO_00884	4.81e-276	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
EPNHKGJO_00885	3.91e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
EPNHKGJO_00886	2.35e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
EPNHKGJO_00887	3.64e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
EPNHKGJO_00889	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
EPNHKGJO_00890	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_00891	3.78e-10	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
EPNHKGJO_00892	6.95e-159	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
EPNHKGJO_00893	3.57e-188	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
EPNHKGJO_00894	5.88e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_00895	8.41e-298	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
EPNHKGJO_00896	9.83e-165	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_00897	8.4e-235	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
EPNHKGJO_00898	3.14e-178	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_00899	9.27e-249	-	-	-	L	-	-	-	Replication protein
EPNHKGJO_00900	9.19e-55	-	-	-	-	-	-	-	-
EPNHKGJO_00903	3.27e-300	pre	-	-	D	-	-	-	plasmid recombination enzyme
EPNHKGJO_00904	1.73e-97	-	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00906	1.08e-135	rapE	-	-	S	ko:K06363	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
EPNHKGJO_00907	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPNHKGJO_00908	3.81e-71	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPNHKGJO_00909	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
EPNHKGJO_00910	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
EPNHKGJO_00912	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
EPNHKGJO_00913	1.4e-281	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
EPNHKGJO_00914	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EPNHKGJO_00915	9.16e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
EPNHKGJO_00916	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
EPNHKGJO_00917	1.5e-204	yybS	-	-	S	-	-	-	membrane
EPNHKGJO_00919	6.16e-20	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
EPNHKGJO_00920	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00921	1.4e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
EPNHKGJO_00922	2.07e-43	-	-	-	-	-	-	-	-
EPNHKGJO_00923	7e-36	-	-	-	-	-	-	-	-
EPNHKGJO_00925	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_00926	5.1e-141	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
EPNHKGJO_00927	4.62e-180	-	-	-	-	-	-	-	-
EPNHKGJO_00928	5.02e-87	-	-	-	S	-	-	-	SnoaL-like domain
EPNHKGJO_00929	1.09e-159	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
EPNHKGJO_00930	4.5e-129	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_00931	3.29e-102	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
EPNHKGJO_00932	1.85e-99	yybA	-	-	K	-	-	-	transcriptional
EPNHKGJO_00933	4.18e-90	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
EPNHKGJO_00934	1.01e-123	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
EPNHKGJO_00935	3.86e-119	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
EPNHKGJO_00936	7.41e-86	-	-	-	S	-	-	-	YjbR
EPNHKGJO_00937	7.09e-136	yyaP	-	-	H	-	-	-	RibD C-terminal domain
EPNHKGJO_00938	7.74e-312	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_00939	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
EPNHKGJO_00940	2.1e-215	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EPNHKGJO_00941	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
EPNHKGJO_00942	6.07e-126	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
EPNHKGJO_00943	3.3e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPNHKGJO_00944	4.83e-227	ccpB	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00945	9.83e-186	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
EPNHKGJO_00946	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EPNHKGJO_00947	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EPNHKGJO_00948	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
EPNHKGJO_00949	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EPNHKGJO_00950	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPNHKGJO_00951	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_00952	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
EPNHKGJO_00953	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
EPNHKGJO_00954	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
EPNHKGJO_00955	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
EPNHKGJO_00956	8.9e-96	-	-	-	S	-	-	-	Bacterial PH domain
EPNHKGJO_00957	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EPNHKGJO_00958	1.01e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EPNHKGJO_00959	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EPNHKGJO_00960	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EPNHKGJO_00961	2.14e-140	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
EPNHKGJO_00962	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPNHKGJO_00963	1.64e-70	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EPNHKGJO_00964	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EPNHKGJO_00965	4.69e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EPNHKGJO_00966	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
EPNHKGJO_00967	3.73e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EPNHKGJO_00968	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
EPNHKGJO_00969	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPNHKGJO_00970	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPNHKGJO_00971	2.35e-248	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
EPNHKGJO_00972	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
EPNHKGJO_00973	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPNHKGJO_00974	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPNHKGJO_00975	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EPNHKGJO_00976	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPNHKGJO_00977	3.45e-189	yerO	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_00978	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPNHKGJO_00979	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EPNHKGJO_00980	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPNHKGJO_00982	5.6e-125	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
EPNHKGJO_00984	4e-40	-	-	-	S	-	-	-	Colicin immunity protein / pyocin immunity protein
EPNHKGJO_00986	1.73e-108	-	-	-	S	-	-	-	Protein of unknown function, DUF600
EPNHKGJO_00987	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
EPNHKGJO_00988	2.38e-121	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
EPNHKGJO_00989	1.06e-73	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
EPNHKGJO_00990	1.73e-271	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
EPNHKGJO_00992	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
EPNHKGJO_00994	9.52e-128	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_00995	7.67e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
EPNHKGJO_00996	9.4e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
EPNHKGJO_00997	6.05e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
EPNHKGJO_00998	4.15e-131	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
EPNHKGJO_01000	7.03e-130	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
EPNHKGJO_01001	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_01002	1.82e-255	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
EPNHKGJO_01003	3.39e-313	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
EPNHKGJO_01004	8.23e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPNHKGJO_01005	6.38e-78	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPNHKGJO_01006	8.14e-115	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPNHKGJO_01007	2.29e-253	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
EPNHKGJO_01008	2.77e-254	yesS	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_01009	6.99e-244	yesS	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_01010	3.83e-166	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
EPNHKGJO_01011	4.88e-161	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
EPNHKGJO_01012	3.17e-142	-	-	-	S	-	-	-	Protein of unknown function, DUF624
EPNHKGJO_01013	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
EPNHKGJO_01014	2.76e-206	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
EPNHKGJO_01015	1.35e-206	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
EPNHKGJO_01016	6.17e-158	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
EPNHKGJO_01017	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
EPNHKGJO_01018	0.0	yetA	-	-	-	-	-	-	-
EPNHKGJO_01019	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
EPNHKGJO_01020	2.39e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
EPNHKGJO_01021	1.3e-207	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPNHKGJO_01022	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
EPNHKGJO_01023	7.07e-155	yetF	-	-	S	-	-	-	membrane
EPNHKGJO_01024	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
EPNHKGJO_01025	3.51e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPNHKGJO_01026	2.61e-49	-	-	-	-	-	-	-	-
EPNHKGJO_01027	1.03e-183	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPNHKGJO_01028	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
EPNHKGJO_01029	5.15e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
EPNHKGJO_01030	5.07e-38	yetM	-	-	CH	-	-	-	FAD binding domain
EPNHKGJO_01031	2.81e-172	-	-	-	M	-	-	-	Membrane
EPNHKGJO_01032	1.06e-176	-	-	-	I	ko:K01066	-	ko00000,ko01000	esterase
EPNHKGJO_01033	3.54e-62	ohrB	-	-	O	-	-	-	OsmC-like protein
EPNHKGJO_01034	7.77e-65	ohrR	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_01036	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
EPNHKGJO_01037	1.1e-72	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPNHKGJO_01038	9.81e-47	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
EPNHKGJO_01039	1.49e-167	-	-	-	-	-	-	-	-
EPNHKGJO_01040	8.9e-216	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
EPNHKGJO_01041	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
EPNHKGJO_01042	1.33e-173	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
EPNHKGJO_01043	6.41e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
EPNHKGJO_01045	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
EPNHKGJO_01046	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EPNHKGJO_01047	3.3e-198	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EPNHKGJO_01048	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
EPNHKGJO_01049	5.83e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EPNHKGJO_01050	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
EPNHKGJO_01051	6.61e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EPNHKGJO_01052	9.8e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
EPNHKGJO_01053	1.1e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPNHKGJO_01054	6.65e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
EPNHKGJO_01055	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
EPNHKGJO_01056	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
EPNHKGJO_01057	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
EPNHKGJO_01058	2.74e-242	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
EPNHKGJO_01059	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
EPNHKGJO_01060	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EPNHKGJO_01061	2.73e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
EPNHKGJO_01062	7.06e-70	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
EPNHKGJO_01063	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EPNHKGJO_01064	1.96e-274	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
EPNHKGJO_01065	3.88e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EPNHKGJO_01066	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EPNHKGJO_01067	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
EPNHKGJO_01068	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EPNHKGJO_01069	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
EPNHKGJO_01070	1.38e-178	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EPNHKGJO_01071	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
EPNHKGJO_01072	1.34e-199	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
EPNHKGJO_01073	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
EPNHKGJO_01074	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
EPNHKGJO_01075	7.62e-290	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
EPNHKGJO_01076	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
EPNHKGJO_01077	3.13e-79	yqfB	-	-	-	-	-	-	-
EPNHKGJO_01078	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
EPNHKGJO_01079	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
EPNHKGJO_01080	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
EPNHKGJO_01082	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
EPNHKGJO_01083	2.49e-105	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EPNHKGJO_01084	2.26e-78	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
EPNHKGJO_01085	5.52e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EPNHKGJO_01086	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EPNHKGJO_01087	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
EPNHKGJO_01088	1.24e-185	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
EPNHKGJO_01089	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
EPNHKGJO_01090	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
EPNHKGJO_01091	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
EPNHKGJO_01092	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EPNHKGJO_01093	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
EPNHKGJO_01094	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EPNHKGJO_01095	2.29e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EPNHKGJO_01096	2.29e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
EPNHKGJO_01097	5.67e-149	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
EPNHKGJO_01098	2.44e-265	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EPNHKGJO_01099	1.14e-131	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
EPNHKGJO_01100	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
EPNHKGJO_01101	3.89e-248	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
EPNHKGJO_01102	2.76e-283	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
EPNHKGJO_01103	3.62e-142	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPNHKGJO_01108	7.27e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
EPNHKGJO_01111	2.64e-21	-	-	-	K	-	-	-	Helix-turn-helix domain
EPNHKGJO_01114	2.88e-270	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
EPNHKGJO_01117	7.55e-84	-	-	-	-	-	-	-	-
EPNHKGJO_01118	5.69e-224	-	-	-	-	-	-	-	-
EPNHKGJO_01119	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EPNHKGJO_01120	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
EPNHKGJO_01121	1.74e-119	yobW	-	-	-	-	-	-	-
EPNHKGJO_01122	6.31e-224	yobV	-	-	K	-	-	-	WYL domain
EPNHKGJO_01123	4.8e-111	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
EPNHKGJO_01124	3.16e-168	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
EPNHKGJO_01125	8.85e-127	yobS	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_01126	5.67e-178	-	-	-	J	-	-	-	FR47-like protein
EPNHKGJO_01127	8.68e-174	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
EPNHKGJO_01128	8.66e-70	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
EPNHKGJO_01133	3.38e-232	-	-	-	-	-	-	-	-
EPNHKGJO_01136	1.36e-12	-	-	-	-	-	-	-	-
EPNHKGJO_01145	3.18e-08	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH nucleases
EPNHKGJO_01146	3.82e-29	-	-	-	-	-	-	-	-
EPNHKGJO_01147	1.63e-308	-	-	-	L	-	-	-	Phage Terminase
EPNHKGJO_01148	1.26e-144	-	-	-	N	-	-	-	Portal protein
EPNHKGJO_01149	7.41e-65	-	-	-	S	-	-	-	Caudovirus prohead serine protease
EPNHKGJO_01150	1.01e-136	-	-	-	S	-	-	-	Phage capsid family
EPNHKGJO_01153	3.85e-21	-	-	-	S	-	-	-	TIGRFAM phage protein, HK97 gp10 family
EPNHKGJO_01155	1.02e-66	-	-	-	S	-	-	-	phage major tail protein, phi13 family
EPNHKGJO_01156	0.00038	-	-	-	-	-	-	-	-
EPNHKGJO_01158	1.87e-161	-	-	-	D	-	-	-	Phage-related minor tail protein
EPNHKGJO_01160	8.2e-126	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
EPNHKGJO_01161	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
EPNHKGJO_01164	3.44e-302	-	-	-	-	-	-	-	-
EPNHKGJO_01165	4.68e-06	-	-	-	L	-	-	-	SNF2 family N-terminal domain
EPNHKGJO_01166	5.75e-42	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
EPNHKGJO_01167	1.45e-231	xkdQ	-	-	G	-	-	-	NLP P60 protein
EPNHKGJO_01168	6.56e-156	xkdP	-	-	S	-	-	-	Lysin motif
EPNHKGJO_01169	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
EPNHKGJO_01170	9.14e-88	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
EPNHKGJO_01172	7.03e-98	xkdM	-	-	S	-	-	-	Phage tail tube protein
EPNHKGJO_01173	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
EPNHKGJO_01174	1.21e-34	-	-	-	-	-	-	-	-
EPNHKGJO_01175	1.48e-98	yqbJ	-	-	-	-	-	-	-
EPNHKGJO_01176	1.79e-112	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
EPNHKGJO_01177	9.68e-83	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
EPNHKGJO_01178	1.43e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
EPNHKGJO_01179	2.12e-60	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
EPNHKGJO_01180	8.83e-214	xkdG	-	-	S	-	-	-	Phage capsid family
EPNHKGJO_01181	4.23e-158	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
EPNHKGJO_01183	1.79e-194	-	-	-	S	-	-	-	Phage Mu protein F like protein
EPNHKGJO_01184	0.0	yqbA	-	-	S	-	-	-	portal protein
EPNHKGJO_01185	2.69e-312	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
EPNHKGJO_01186	7.73e-147	yqaS	-	-	L	-	-	-	DNA packaging
EPNHKGJO_01188	5.27e-95	yqaQ	-	-	L	-	-	-	Transposase
EPNHKGJO_01189	3.63e-184	ddeI	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
EPNHKGJO_01190	5.34e-138	-	-	-	L	-	-	-	SacI restriction endonuclease
EPNHKGJO_01191	2.92e-42	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
EPNHKGJO_01192	1.14e-96	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
EPNHKGJO_01194	2.14e-208	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
EPNHKGJO_01195	2.41e-152	yqaL	-	-	L	-	-	-	DnaD domain protein
EPNHKGJO_01196	2.39e-193	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
EPNHKGJO_01197	1.37e-221	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
EPNHKGJO_01201	1.43e-131	-	-	-	-	-	-	-	-
EPNHKGJO_01203	1.54e-24	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
EPNHKGJO_01204	1.88e-42	-	-	-	K	-	-	-	sequence-specific DNA binding
EPNHKGJO_01206	1.85e-121	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
EPNHKGJO_01207	4.46e-79	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPNHKGJO_01208	5.15e-42	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EPNHKGJO_01210	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPNHKGJO_01211	1.05e-276	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPNHKGJO_01212	1.15e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
EPNHKGJO_01213	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
EPNHKGJO_01214	7.54e-22	-	-	-	-	-	-	-	-
EPNHKGJO_01217	2.43e-106	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPNHKGJO_01219	1.21e-264	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
EPNHKGJO_01220	3.28e-48	-	-	-	S	-	-	-	Bacteriophage holin
EPNHKGJO_01222	2.43e-100	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
EPNHKGJO_01225	4.19e-97	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
EPNHKGJO_01226	2.17e-30	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
EPNHKGJO_01227	1.36e-12	-	-	-	-	-	-	-	-
EPNHKGJO_01228	3.43e-66	bldD	-	-	K	ko:K07110,ko:K21572	-	ko00000,ko02000,ko03000	domain, Protein
EPNHKGJO_01229	2.75e-19	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EPNHKGJO_01230	1.62e-19	-	-	-	S	-	-	-	Helix-turn-helix domain
EPNHKGJO_01231	3.29e-57	-	-	-	-	-	-	-	-
EPNHKGJO_01235	1.31e-232	-	-	-	D	-	-	-	nuclear chromosome segregation
EPNHKGJO_01237	6.24e-107	bet	-	-	L	-	-	-	RecT family
EPNHKGJO_01238	7.25e-133	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
EPNHKGJO_01240	3.12e-33	-	-	-	L	-	-	-	primosome component and related proteins
EPNHKGJO_01242	1.85e-227	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
EPNHKGJO_01245	1.03e-63	-	3.1.22.4	-	-	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	-
EPNHKGJO_01246	8.24e-96	-	-	-	-	-	-	-	-
EPNHKGJO_01248	6.56e-25	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
EPNHKGJO_01250	5.54e-34	-	-	-	-	-	-	-	-
EPNHKGJO_01255	9.18e-78	-	-	-	-	-	-	-	-
EPNHKGJO_01256	1.73e-50	-	-	-	-	-	-	-	-
EPNHKGJO_01258	3.56e-05	-	-	-	-	-	-	-	-
EPNHKGJO_01261	2.85e-73	-	-	-	K	-	-	-	DNA binding
EPNHKGJO_01262	2.13e-160	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EPNHKGJO_01263	7.82e-42	-	-	-	-	-	-	-	-
EPNHKGJO_01264	5.13e-107	-	-	-	-	-	-	-	-
EPNHKGJO_01265	1.09e-288	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
EPNHKGJO_01266	7.34e-316	yqbA	-	-	S	-	-	-	portal protein
EPNHKGJO_01267	2.75e-182	-	-	-	S	-	-	-	Phage Mu protein F like protein
EPNHKGJO_01268	1.04e-21	-	-	-	-	-	-	-	-
EPNHKGJO_01269	4.5e-130	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
EPNHKGJO_01270	1.49e-189	xkdG	-	-	S	-	-	-	Phage capsid family
EPNHKGJO_01271	1.53e-33	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
EPNHKGJO_01272	4.84e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
EPNHKGJO_01273	1.61e-72	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
EPNHKGJO_01274	1.3e-107	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
EPNHKGJO_01275	1.8e-90	yqbJ	-	-	-	-	-	-	-
EPNHKGJO_01276	3.49e-32	-	-	-	-	-	-	-	-
EPNHKGJO_01277	5.87e-311	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
EPNHKGJO_01278	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
EPNHKGJO_01279	2.45e-87	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
EPNHKGJO_01280	1.89e-22	-	-	-	-	-	-	-	-
EPNHKGJO_01281	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
EPNHKGJO_01282	2.59e-151	xkdP	-	-	S	-	-	-	Lysin motif
EPNHKGJO_01283	9.35e-228	xkdQ	-	-	G	-	-	-	NLP P60 protein
EPNHKGJO_01284	6.68e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
EPNHKGJO_01285	1.14e-91	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
EPNHKGJO_01286	1.31e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EPNHKGJO_01287	2.65e-133	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
EPNHKGJO_01288	3e-54	-	-	-	-	-	-	-	-
EPNHKGJO_01289	1.19e-282	-	-	-	-	-	-	-	-
EPNHKGJO_01290	1.01e-73	xkdW	-	-	S	-	-	-	XkdW protein
EPNHKGJO_01291	9.34e-33	-	-	-	-	-	-	-	-
EPNHKGJO_01292	2.45e-213	xepA	-	-	-	-	-	-	-
EPNHKGJO_01293	8.36e-89	-	-	-	S	-	-	-	Bacteriophage holin family
EPNHKGJO_01294	9.72e-187	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
EPNHKGJO_01296	5.4e-80	-	-	-	-	-	-	-	-
EPNHKGJO_01298	1.6e-134	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
EPNHKGJO_01299	1.74e-62	-	-	-	-	-	-	-	-
EPNHKGJO_01300	9.34e-20	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
EPNHKGJO_01303	5.7e-287	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EPNHKGJO_01304	1.91e-91	-	-	-	K	-	-	-	MerR family transcriptional regulator
EPNHKGJO_01305	3.68e-176	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Reductase
EPNHKGJO_01306	6.04e-170	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
EPNHKGJO_01308	1.76e-122	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_01309	3.22e-240	-	-	-	T	-	-	-	Histidine kinase
EPNHKGJO_01310	2.92e-165	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
EPNHKGJO_01311	5.51e-121	hrtA	-	-	V	ko:K02003,ko:K09814	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
EPNHKGJO_01319	5.55e-49	wapA	-	-	M	-	-	-	RHS family
EPNHKGJO_01320	1.27e-69	-	-	-	-	-	-	-	-
EPNHKGJO_01322	2.06e-174	-	-	-	-	-	-	-	-
EPNHKGJO_01323	8.9e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF4240)
EPNHKGJO_01324	7.13e-100	-	-	-	-	-	-	-	-
EPNHKGJO_01325	1.1e-58	-	-	-	-	-	-	-	-
EPNHKGJO_01326	4.67e-89	yxiG	-	-	-	-	-	-	-
EPNHKGJO_01327	9.7e-68	yxxG	-	-	-	-	-	-	-
EPNHKGJO_01328	6.09e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2750)
EPNHKGJO_01331	3.29e-19	yxiJ	-	-	S	-	-	-	YxiJ-like protein
EPNHKGJO_01332	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
EPNHKGJO_01333	1.99e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
EPNHKGJO_01334	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
EPNHKGJO_01335	2.02e-217	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EPNHKGJO_01336	1.99e-82	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EPNHKGJO_01337	1.56e-53	-	-	-	-	-	-	-	-
EPNHKGJO_01338	5.35e-102	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
EPNHKGJO_01339	0.0	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
EPNHKGJO_01340	3.27e-53	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
EPNHKGJO_01341	6.24e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
EPNHKGJO_01342	2.96e-64	-	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
EPNHKGJO_01343	4.76e-233	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
EPNHKGJO_01344	7.83e-111	-	-	-	S	-	-	-	GTP binding
EPNHKGJO_01345	2.51e-95	-	-	-	L	-	-	-	NgoFVII restriction endonuclease
EPNHKGJO_01346	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
EPNHKGJO_01347	3.11e-100	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EPNHKGJO_01348	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
EPNHKGJO_01349	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EPNHKGJO_01350	5.49e-300	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
EPNHKGJO_01351	3.41e-231	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EPNHKGJO_01352	3.42e-67	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
EPNHKGJO_01353	7.08e-201	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
EPNHKGJO_01354	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
EPNHKGJO_01355	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPNHKGJO_01356	8.3e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EPNHKGJO_01357	1.17e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EPNHKGJO_01358	8.36e-133	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
EPNHKGJO_01359	7.95e-41	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
EPNHKGJO_01360	7.72e-256	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
EPNHKGJO_01361	1.34e-312	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
EPNHKGJO_01362	8.27e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
EPNHKGJO_01363	5.6e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_01364	3e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
EPNHKGJO_01365	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
EPNHKGJO_01366	6.03e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPNHKGJO_01367	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPNHKGJO_01368	1.92e-237	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
EPNHKGJO_01369	5.69e-194	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
EPNHKGJO_01372	7.32e-42	yxeE	-	-	-	-	-	-	-
EPNHKGJO_01373	7.57e-28	yxeD	-	-	-	-	-	-	-
EPNHKGJO_01374	6.79e-91	-	-	-	-	-	-	-	-
EPNHKGJO_01375	7.4e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPNHKGJO_01376	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
EPNHKGJO_01377	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
EPNHKGJO_01378	3.01e-178	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_01379	1.1e-230	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_01380	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_01381	2.83e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EPNHKGJO_01382	2.67e-192	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EPNHKGJO_01383	4.4e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
EPNHKGJO_01384	1.27e-250	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EPNHKGJO_01385	2.32e-295	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
EPNHKGJO_01386	4.1e-221	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EPNHKGJO_01387	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EPNHKGJO_01388	3.52e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EPNHKGJO_01389	1.46e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EPNHKGJO_01390	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPNHKGJO_01391	9.02e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
EPNHKGJO_01392	1.43e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
EPNHKGJO_01394	8.67e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
EPNHKGJO_01395	3.41e-312	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPNHKGJO_01396	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
EPNHKGJO_01398	8.38e-193	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
EPNHKGJO_01399	1.03e-265	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EPNHKGJO_01400	2.4e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
EPNHKGJO_01401	2.09e-16	yxaI	-	-	S	-	-	-	membrane protein domain
EPNHKGJO_01402	1.73e-135	yxaL	-	-	S	-	-	-	PQQ-like domain
EPNHKGJO_01403	5.94e-78	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
EPNHKGJO_01404	8.13e-99	yxaI	-	-	S	-	-	-	membrane protein domain
EPNHKGJO_01405	3.08e-285	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
EPNHKGJO_01406	7.9e-246	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
EPNHKGJO_01407	9.61e-131	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
EPNHKGJO_01408	7.12e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNHKGJO_01409	2.07e-82	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
EPNHKGJO_01411	8.77e-215	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	methionine gamma-lyase
EPNHKGJO_01412	1.3e-27	-	-	-	I	-	-	-	Fatty acid desaturase
EPNHKGJO_01413	4.23e-100	-	-	-	I	-	-	-	Fatty acid desaturase
EPNHKGJO_01414	0.000162	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
EPNHKGJO_01415	3.78e-250	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPNHKGJO_01416	2.5e-174	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
EPNHKGJO_01417	1.05e-187	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
EPNHKGJO_01418	1.65e-194	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
EPNHKGJO_01419	2.72e-79	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
EPNHKGJO_01420	1.51e-234	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EPNHKGJO_01421	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
EPNHKGJO_01422	7.86e-266	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
EPNHKGJO_01424	3.35e-56	-	-	-	-	-	-	-	-
EPNHKGJO_01426	1.65e-286	-	-	-	S	-	-	-	hydrolase activity
EPNHKGJO_01429	1.05e-223	-	-	-	-	-	-	-	-
EPNHKGJO_01430	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EPNHKGJO_01431	1.56e-44	yqfQ	-	-	S	-	-	-	YqfQ-like protein
EPNHKGJO_01432	1.09e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EPNHKGJO_01433	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EPNHKGJO_01434	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
EPNHKGJO_01435	2.21e-198	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
EPNHKGJO_01436	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
EPNHKGJO_01437	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
EPNHKGJO_01438	6.82e-80	yqfX	-	-	S	-	-	-	membrane
EPNHKGJO_01439	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EPNHKGJO_01440	1.35e-61	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
EPNHKGJO_01441	2.74e-168	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
EPNHKGJO_01442	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
EPNHKGJO_01443	1.31e-147	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
EPNHKGJO_01444	1.54e-290	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
EPNHKGJO_01445	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
EPNHKGJO_01446	7.59e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
EPNHKGJO_01447	8.29e-202	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
EPNHKGJO_01448	2.14e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
EPNHKGJO_01449	9.78e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPNHKGJO_01450	1.29e-185	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPNHKGJO_01451	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
EPNHKGJO_01452	2.81e-67	yqzD	-	-	-	-	-	-	-
EPNHKGJO_01454	1.56e-254	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
EPNHKGJO_01455	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
EPNHKGJO_01456	3.8e-135	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EPNHKGJO_01457	3.38e-14	yqgO	-	-	-	-	-	-	-
EPNHKGJO_01458	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
EPNHKGJO_01459	2.11e-42	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
EPNHKGJO_01460	1.62e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
EPNHKGJO_01461	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
EPNHKGJO_01462	5.04e-282	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
EPNHKGJO_01463	7.7e-256	yqgU	-	-	-	-	-	-	-
EPNHKGJO_01464	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
EPNHKGJO_01465	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
EPNHKGJO_01466	3.07e-155	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
EPNHKGJO_01467	1.41e-48	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
EPNHKGJO_01468	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
EPNHKGJO_01470	2.29e-188	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPNHKGJO_01471	1.65e-304	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
EPNHKGJO_01472	2.4e-230	yqxL	-	-	P	-	-	-	Mg2 transporter protein
EPNHKGJO_01473	1.28e-256	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EPNHKGJO_01474	2.55e-211	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
EPNHKGJO_01475	1.26e-61	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
EPNHKGJO_01476	5.39e-91	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
EPNHKGJO_01477	3.45e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
EPNHKGJO_01478	1.17e-59	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
EPNHKGJO_01479	3.78e-57	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
EPNHKGJO_01480	2.84e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
EPNHKGJO_01481	3.68e-70	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
EPNHKGJO_01482	1.92e-128	yqxM	-	-	-	ko:K19433	-	ko00000	-
EPNHKGJO_01483	1.74e-96	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
EPNHKGJO_01484	9e-182	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
EPNHKGJO_01485	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
EPNHKGJO_01486	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
EPNHKGJO_01487	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
EPNHKGJO_01488	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
EPNHKGJO_01489	1.91e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
EPNHKGJO_01490	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EPNHKGJO_01491	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EPNHKGJO_01492	2.51e-81	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
EPNHKGJO_01493	2.63e-203	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EPNHKGJO_01494	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EPNHKGJO_01495	9.94e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
EPNHKGJO_01496	5.18e-81	yqhP	-	-	-	-	-	-	-
EPNHKGJO_01497	4.95e-219	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
EPNHKGJO_01498	3.27e-120	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
EPNHKGJO_01499	1.94e-100	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
EPNHKGJO_01500	2.99e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
EPNHKGJO_01501	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPNHKGJO_01502	9.89e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
EPNHKGJO_01503	8.22e-217	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
EPNHKGJO_01504	5.69e-111	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
EPNHKGJO_01505	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
EPNHKGJO_01506	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
EPNHKGJO_01507	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
EPNHKGJO_01508	2.58e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
EPNHKGJO_01509	1.08e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
EPNHKGJO_01510	4.04e-134	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
EPNHKGJO_01511	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EPNHKGJO_01512	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EPNHKGJO_01513	9.55e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_01514	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPNHKGJO_01515	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPNHKGJO_01516	3.55e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPNHKGJO_01517	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPNHKGJO_01518	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
EPNHKGJO_01519	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EPNHKGJO_01520	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
EPNHKGJO_01521	4.38e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
EPNHKGJO_01522	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
EPNHKGJO_01523	2.96e-302	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
EPNHKGJO_01524	3.14e-185	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EPNHKGJO_01526	1.15e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EPNHKGJO_01528	1.36e-36	-	-	-	-	-	-	-	-
EPNHKGJO_01529	3.83e-137	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
EPNHKGJO_01530	1.88e-165	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
EPNHKGJO_01531	1.91e-279	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
EPNHKGJO_01532	1.98e-198	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
EPNHKGJO_01533	4.95e-268	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
EPNHKGJO_01534	1.66e-267	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
EPNHKGJO_01535	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
EPNHKGJO_01536	4.18e-207	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EPNHKGJO_01537	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
EPNHKGJO_01538	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
EPNHKGJO_01539	3.02e-199	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
EPNHKGJO_01540	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
EPNHKGJO_01541	1.18e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
EPNHKGJO_01542	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EPNHKGJO_01543	1.92e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EPNHKGJO_01544	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EPNHKGJO_01545	1.87e-288	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPNHKGJO_01546	9.06e-195	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
EPNHKGJO_01547	1.26e-266	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_01548	5.76e-212	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EPNHKGJO_01549	6.29e-100	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
EPNHKGJO_01550	1.43e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
EPNHKGJO_01551	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
EPNHKGJO_01552	1.28e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
EPNHKGJO_01553	1.73e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
EPNHKGJO_01554	4.01e-127	yqjB	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_01556	4.67e-95	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
EPNHKGJO_01557	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EPNHKGJO_01558	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
EPNHKGJO_01559	1.6e-28	-	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_01560	0.0	-	-	-	L	-	-	-	DNA polymerase elongation subunit (Family B)
EPNHKGJO_01561	3e-218	-	-	-	S	-	-	-	PD-(D/E)XK nuclease superfamily
EPNHKGJO_01562	7.25e-188	-	-	-	L	-	-	-	DNA primase activity
EPNHKGJO_01563	5.32e-306	-	-	-	L	-	-	-	DnaB-like helicase C terminal domain
EPNHKGJO_01565	5.06e-209	-	-	-	S	-	-	-	AAA domain
EPNHKGJO_01566	4.8e-223	-	-	-	-	-	-	-	-
EPNHKGJO_01569	1.12e-67	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
EPNHKGJO_01570	5.65e-275	-	-	-	M	-	-	-	Parallel beta-helix repeats
EPNHKGJO_01571	1.99e-108	-	-	-	S	-	-	-	Pfam:DUF867
EPNHKGJO_01573	7.36e-06	-	-	-	S	-	-	-	YopX protein
EPNHKGJO_01575	2.6e-158	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
EPNHKGJO_01576	6.45e-175	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
EPNHKGJO_01578	1.56e-73	-	-	-	-	-	-	-	-
EPNHKGJO_01579	9.95e-70	ybiA	-	-	O	ko:K09935	-	ko00000	Protein conserved in bacteria
EPNHKGJO_01585	1.37e-116	-	-	-	S	-	-	-	Protein of unknown function (DUF1273)
EPNHKGJO_01586	8.64e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPNHKGJO_01587	7.48e-140	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
EPNHKGJO_01588	7.49e-236	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
EPNHKGJO_01589	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
EPNHKGJO_01590	3.78e-74	ydfQ	-	-	CO	-	-	-	Thioredoxin
EPNHKGJO_01591	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
EPNHKGJO_01592	5.33e-39	-	-	-	-	-	-	-	-
EPNHKGJO_01594	4.33e-34	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
EPNHKGJO_01595	4.9e-36	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
EPNHKGJO_01596	8.96e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
EPNHKGJO_01597	1.28e-98	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
EPNHKGJO_01598	5.54e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
EPNHKGJO_01599	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
EPNHKGJO_01600	8.51e-128	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EPNHKGJO_01601	1.97e-111	yycN	-	-	K	-	-	-	Acetyltransferase
EPNHKGJO_01602	1.18e-239	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
EPNHKGJO_01603	2.5e-122	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
EPNHKGJO_01604	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
EPNHKGJO_01605	5.94e-118	-	-	-	S	-	-	-	DinB family
EPNHKGJO_01606	2.06e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EPNHKGJO_01607	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
EPNHKGJO_01608	1.84e-146	ydgI	-	-	C	-	-	-	nitroreductase
EPNHKGJO_01609	1.9e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
EPNHKGJO_01610	4.9e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
EPNHKGJO_01611	2.51e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EPNHKGJO_01612	5.24e-158	ydhC	-	-	K	-	-	-	FCD
EPNHKGJO_01613	2.01e-306	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
EPNHKGJO_01614	6.49e-288	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EPNHKGJO_01615	4.28e-163	-	-	-	-	-	-	-	-
EPNHKGJO_01616	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
EPNHKGJO_01617	5.54e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
EPNHKGJO_01619	7.97e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
EPNHKGJO_01620	3.02e-230	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
EPNHKGJO_01621	7.76e-128	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
EPNHKGJO_01622	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
EPNHKGJO_01623	2.29e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_01624	1.44e-68	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_01625	2.27e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPNHKGJO_01626	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EPNHKGJO_01627	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
EPNHKGJO_01628	5.53e-211	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
EPNHKGJO_01629	1.2e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
EPNHKGJO_01630	5.33e-268	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
EPNHKGJO_01631	3.44e-202	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
EPNHKGJO_01632	7.5e-282	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPNHKGJO_01633	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
EPNHKGJO_01634	5.47e-178	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
EPNHKGJO_01635	3.62e-287	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EPNHKGJO_01636	1.66e-119	-	-	-	S	-	-	-	YcxB-like protein
EPNHKGJO_01637	8.03e-206	ycxC	-	-	EG	-	-	-	EamA-like transporter family
EPNHKGJO_01638	2.04e-300	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
EPNHKGJO_01639	3.91e-144	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
EPNHKGJO_01640	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
EPNHKGJO_01641	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
EPNHKGJO_01642	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
EPNHKGJO_01643	2.39e-185	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
EPNHKGJO_01644	1.71e-205	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
EPNHKGJO_01645	2.33e-142	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EPNHKGJO_01646	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EPNHKGJO_01647	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
EPNHKGJO_01648	1.45e-107	yclD	-	-	-	-	-	-	-
EPNHKGJO_01649	6.42e-201	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
EPNHKGJO_01650	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
EPNHKGJO_01651	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
EPNHKGJO_01653	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
EPNHKGJO_01654	1.22e-289	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
EPNHKGJO_01655	4.24e-250	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
EPNHKGJO_01656	1.18e-155	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
EPNHKGJO_01657	2.59e-274	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
EPNHKGJO_01658	2.09e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_01659	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EPNHKGJO_01660	3.09e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
EPNHKGJO_01662	6.5e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
EPNHKGJO_01663	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
EPNHKGJO_01664	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_01665	4.69e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_01666	3.26e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_01667	1.12e-219	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
EPNHKGJO_01668	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
EPNHKGJO_01669	9.73e-197	ycnC	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_01670	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
EPNHKGJO_01671	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
EPNHKGJO_01672	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
EPNHKGJO_01673	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPNHKGJO_01674	6.58e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPNHKGJO_01675	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPNHKGJO_01676	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
EPNHKGJO_01677	1.39e-185	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_01678	1.34e-132	ycnI	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_01679	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
EPNHKGJO_01680	2.03e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
EPNHKGJO_01681	4.67e-75	-	-	-	-	-	-	-	-
EPNHKGJO_01682	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
EPNHKGJO_01683	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EPNHKGJO_01684	1.72e-265	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
EPNHKGJO_01685	5.86e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
EPNHKGJO_01687	9.86e-94	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
EPNHKGJO_01688	6.98e-143	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
EPNHKGJO_01689	1.89e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
EPNHKGJO_01690	1.31e-121	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
EPNHKGJO_01691	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
EPNHKGJO_01692	6.61e-37	ycgB	-	-	-	-	-	-	-
EPNHKGJO_01693	0.0	ycgA	-	-	S	-	-	-	Membrane
EPNHKGJO_01694	1.05e-271	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
EPNHKGJO_01695	3.33e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
EPNHKGJO_01696	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
EPNHKGJO_01697	2.12e-291	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
EPNHKGJO_01698	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
EPNHKGJO_01699	6.13e-236	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
EPNHKGJO_01700	2.22e-277	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
EPNHKGJO_01701	1.7e-186	-	-	-	S	-	-	-	Phage tail protein
EPNHKGJO_01702	4.13e-51	-	-	-	-	-	-	-	-
EPNHKGJO_01703	4.8e-83	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
EPNHKGJO_01704	2.69e-216	-	-	-	S	-	-	-	Bacterial EndoU nuclease
EPNHKGJO_01705	3.86e-104	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
EPNHKGJO_01707	2.76e-46	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EPNHKGJO_01708	8.04e-96	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
EPNHKGJO_01711	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
EPNHKGJO_01712	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPNHKGJO_01713	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
EPNHKGJO_01714	4.56e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EPNHKGJO_01715	3.12e-79	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EPNHKGJO_01716	9.13e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EPNHKGJO_01717	1.26e-213	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
EPNHKGJO_01718	1.72e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
EPNHKGJO_01719	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPNHKGJO_01720	8.88e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
EPNHKGJO_01721	2.23e-194	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
EPNHKGJO_01722	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EPNHKGJO_01723	2.82e-188	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EPNHKGJO_01724	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EPNHKGJO_01725	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
EPNHKGJO_01726	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EPNHKGJO_01727	6.92e-236	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
EPNHKGJO_01728	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
EPNHKGJO_01729	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
EPNHKGJO_01732	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
EPNHKGJO_01733	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
EPNHKGJO_01734	5.21e-138	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
EPNHKGJO_01735	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
EPNHKGJO_01736	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EPNHKGJO_01737	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EPNHKGJO_01738	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPNHKGJO_01739	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
EPNHKGJO_01740	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPNHKGJO_01741	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
EPNHKGJO_01742	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EPNHKGJO_01743	1.69e-135	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EPNHKGJO_01744	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPNHKGJO_01745	2.58e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EPNHKGJO_01746	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EPNHKGJO_01747	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
EPNHKGJO_01748	1.56e-194	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
EPNHKGJO_01749	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EPNHKGJO_01750	1.28e-35	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
EPNHKGJO_01751	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_01752	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
EPNHKGJO_01753	1.05e-195	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EPNHKGJO_01754	4.09e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EPNHKGJO_01755	1.86e-274	yabE	-	-	T	-	-	-	protein conserved in bacteria
EPNHKGJO_01756	1.39e-182	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
EPNHKGJO_01757	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPNHKGJO_01758	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
EPNHKGJO_01759	7.26e-208	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EPNHKGJO_01760	4.19e-65	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
EPNHKGJO_01761	2.81e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
EPNHKGJO_01762	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
EPNHKGJO_01763	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
EPNHKGJO_01764	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
EPNHKGJO_01765	1.48e-94	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
EPNHKGJO_01766	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_01767	5.46e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPNHKGJO_01768	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
EPNHKGJO_01769	2.92e-259	yaaN	-	-	P	-	-	-	Belongs to the TelA family
EPNHKGJO_01770	1.82e-130	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EPNHKGJO_01771	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
EPNHKGJO_01772	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
EPNHKGJO_01773	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EPNHKGJO_01774	4.54e-241	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
EPNHKGJO_01777	7.14e-11	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
EPNHKGJO_01778	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
EPNHKGJO_01779	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
EPNHKGJO_01780	1.24e-94	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
EPNHKGJO_01781	1.34e-112	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
EPNHKGJO_01782	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EPNHKGJO_01783	4.87e-299	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
EPNHKGJO_01784	3.99e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
EPNHKGJO_01785	9.97e-59	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EPNHKGJO_01786	8.14e-286	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
EPNHKGJO_01788	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
EPNHKGJO_01789	2.29e-176	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_01790	1.2e-202	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EPNHKGJO_01791	5.49e-238	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
EPNHKGJO_01792	4.02e-237	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
EPNHKGJO_01793	5.97e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
EPNHKGJO_01794	5.8e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
EPNHKGJO_01795	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EPNHKGJO_01796	2.34e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EPNHKGJO_01797	2.47e-291	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
EPNHKGJO_01798	1.07e-264	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
EPNHKGJO_01799	4.73e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
EPNHKGJO_01801	0.0	ypbR	-	-	S	-	-	-	Dynamin family
EPNHKGJO_01802	1.66e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
EPNHKGJO_01803	7.57e-12	-	-	-	-	-	-	-	-
EPNHKGJO_01804	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
EPNHKGJO_01805	0.00015	-	-	-	-	ko:K06429	-	ko00000	-
EPNHKGJO_01806	1.6e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
EPNHKGJO_01807	7.39e-156	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EPNHKGJO_01808	1.9e-161	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
EPNHKGJO_01809	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
EPNHKGJO_01810	1.05e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
EPNHKGJO_01811	1.17e-22	degR	-	-	-	-	-	-	-
EPNHKGJO_01812	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
EPNHKGJO_01813	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EPNHKGJO_01814	5e-224	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EPNHKGJO_01815	3.66e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
EPNHKGJO_01816	6.48e-75	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
EPNHKGJO_01817	8.52e-206	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
EPNHKGJO_01818	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
EPNHKGJO_01819	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
EPNHKGJO_01820	4.65e-182	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
EPNHKGJO_01821	4.51e-141	ypjP	-	-	S	-	-	-	YpjP-like protein
EPNHKGJO_01822	5.16e-120	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
EPNHKGJO_01823	2.43e-201	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPNHKGJO_01824	7.88e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EPNHKGJO_01825	1.15e-143	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EPNHKGJO_01826	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
EPNHKGJO_01827	1.34e-234	yplP	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_01828	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EPNHKGJO_01829	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
EPNHKGJO_01830	5.15e-136	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EPNHKGJO_01831	1.49e-177	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
EPNHKGJO_01832	1.95e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_01833	1.24e-39	ypmT	-	-	S	-	-	-	Uncharacterized ympT
EPNHKGJO_01834	3.33e-288	mepA	-	-	V	-	-	-	MATE efflux family protein
EPNHKGJO_01835	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
EPNHKGJO_01836	1.63e-131	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPNHKGJO_01837	2.04e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
EPNHKGJO_01838	1.76e-124	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
EPNHKGJO_01839	6.49e-304	yokA	-	-	L	-	-	-	Recombinase
EPNHKGJO_01841	3.89e-85	-	-	-	S	-	-	-	SMI1 / KNR4 family
EPNHKGJO_01842	6.52e-72	-	-	-	S	-	-	-	DNase/tRNase domain of colicin-like bacteriocin
EPNHKGJO_01843	9.7e-63	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
EPNHKGJO_01844	1.55e-133	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
EPNHKGJO_01845	2.57e-19	-	-	-	-	-	-	-	-
EPNHKGJO_01846	6.63e-79	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
EPNHKGJO_01847	2.88e-95	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
EPNHKGJO_01848	6.58e-101	yoaW	-	-	-	-	-	-	-
EPNHKGJO_01849	4.14e-198	yoaV	-	-	EG	-	-	-	EamA-like transporter family
EPNHKGJO_01850	4.16e-201	yoaU	-	-	K	-	-	-	LysR substrate binding domain
EPNHKGJO_01851	7.76e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
EPNHKGJO_01852	7.19e-41	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_01853	3.22e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
EPNHKGJO_01854	5.78e-215	yoaR	-	-	V	-	-	-	vancomycin resistance protein
EPNHKGJO_01855	2.35e-48	-	-	-	-	-	-	-	-
EPNHKGJO_01858	6.5e-65	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
EPNHKGJO_01859	1.45e-207	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
EPNHKGJO_01861	4.69e-167	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
EPNHKGJO_01862	3.94e-250	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
EPNHKGJO_01863	7.3e-145	yoaK	-	-	S	-	-	-	Membrane
EPNHKGJO_01864	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
EPNHKGJO_01865	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
EPNHKGJO_01866	2.56e-228	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
EPNHKGJO_01867	6.78e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
EPNHKGJO_01868	1.46e-19	-	-	-	-	-	-	-	-
EPNHKGJO_01870	3.59e-45	yoaF	-	-	-	-	-	-	-
EPNHKGJO_01871	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPNHKGJO_01872	4.77e-234	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPNHKGJO_01873	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
EPNHKGJO_01874	7.48e-299	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
EPNHKGJO_01875	3.87e-103	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EPNHKGJO_01876	3.01e-178	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
EPNHKGJO_01877	5.07e-121	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
EPNHKGJO_01878	1.78e-167	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
EPNHKGJO_01879	1.34e-121	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EPNHKGJO_01880	1.09e-89	yoxB	-	-	-	-	-	-	-
EPNHKGJO_01881	3.84e-51	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
EPNHKGJO_01882	7.94e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNHKGJO_01883	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EPNHKGJO_01884	3.18e-184	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPNHKGJO_01885	3.86e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPNHKGJO_01886	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_01887	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
EPNHKGJO_01888	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EPNHKGJO_01889	1.15e-234	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EPNHKGJO_01890	1.45e-199	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_01891	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
EPNHKGJO_01892	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
EPNHKGJO_01893	1.14e-124	-	-	-	L	-	-	-	Integrase
EPNHKGJO_01895	7.14e-128	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
EPNHKGJO_01896	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
EPNHKGJO_01897	1.11e-239	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
EPNHKGJO_01898	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
EPNHKGJO_01899	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPNHKGJO_01900	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPNHKGJO_01901	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
EPNHKGJO_01902	3.06e-185	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
EPNHKGJO_01903	3.64e-192	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
EPNHKGJO_01904	3.39e-42	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
EPNHKGJO_01905	2.12e-84	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
EPNHKGJO_01906	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
EPNHKGJO_01907	7.28e-266	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
EPNHKGJO_01908	4.82e-241	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EPNHKGJO_01909	1.83e-112	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EPNHKGJO_01910	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
EPNHKGJO_01911	1.98e-40	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
EPNHKGJO_01912	1.36e-211	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
EPNHKGJO_01913	8.22e-173	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
EPNHKGJO_01914	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EPNHKGJO_01915	7.39e-296	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
EPNHKGJO_01916	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
EPNHKGJO_01917	2.74e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
EPNHKGJO_01918	1.04e-98	yngA	-	-	S	-	-	-	membrane
EPNHKGJO_01919	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
EPNHKGJO_01920	2.08e-171	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
EPNHKGJO_01921	2.12e-114	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
EPNHKGJO_01923	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
EPNHKGJO_01924	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
EPNHKGJO_01925	8.74e-75	ynfC	-	-	-	-	-	-	-
EPNHKGJO_01926	1.82e-18	-	-	-	-	-	-	-	-
EPNHKGJO_01927	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPNHKGJO_01928	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPNHKGJO_01929	1.21e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
EPNHKGJO_01930	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EPNHKGJO_01931	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
EPNHKGJO_01932	5.48e-70	yneQ	-	-	-	-	-	-	-
EPNHKGJO_01933	1.4e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
EPNHKGJO_01934	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
EPNHKGJO_01936	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
EPNHKGJO_01937	3.74e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EPNHKGJO_01938	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EPNHKGJO_01939	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
EPNHKGJO_01940	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
EPNHKGJO_01941	5.77e-85	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
EPNHKGJO_01942	3.97e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
EPNHKGJO_01943	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
EPNHKGJO_01944	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
EPNHKGJO_01945	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
EPNHKGJO_01946	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
EPNHKGJO_01947	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
EPNHKGJO_01948	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
EPNHKGJO_01949	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPNHKGJO_01950	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
EPNHKGJO_01951	2.68e-143	yneB	-	-	L	-	-	-	resolvase
EPNHKGJO_01952	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EPNHKGJO_01953	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPNHKGJO_01954	1.22e-101	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EPNHKGJO_01955	8.65e-119	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
EPNHKGJO_01956	5.4e-174	yndL	-	-	S	-	-	-	Replication protein
EPNHKGJO_01958	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
EPNHKGJO_01959	8.07e-146	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
EPNHKGJO_01960	5.29e-198	yndG	-	-	S	-	-	-	DoxX-like family
EPNHKGJO_01961	6.51e-241	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
EPNHKGJO_01962	2.18e-247	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
EPNHKGJO_01963	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
EPNHKGJO_01966	1.81e-103	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
EPNHKGJO_01967	2.59e-70	-	-	-	-	-	-	-	-
EPNHKGJO_01968	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
EPNHKGJO_01971	9.38e-162	-	-	-	S	-	-	-	Domain of unknown function, YrpD
EPNHKGJO_01973	8.27e-40	-	-	-	-	-	-	-	-
EPNHKGJO_01974	2.64e-208	-	-	-	S	-	-	-	Thymidylate synthase
EPNHKGJO_01977	1.85e-70	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
EPNHKGJO_01978	1.88e-106	-	-	-	S	-	-	-	Bacterial PH domain
EPNHKGJO_01979	2.73e-196	yokD	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	aminoglycoside
EPNHKGJO_01980	8.09e-53	-	-	-	-	-	-	-	-
EPNHKGJO_01983	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPNHKGJO_01984	1.18e-122	-	-	-	S	-	-	-	A nuclease of the HNH/ENDO VII superfamily with conserved WHH
EPNHKGJO_01985	8.39e-65	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
EPNHKGJO_01986	4.12e-88	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
EPNHKGJO_01991	1.9e-231	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EPNHKGJO_01992	1.82e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
EPNHKGJO_01993	2.8e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
EPNHKGJO_01994	4.91e-109	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EPNHKGJO_01995	2.71e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EPNHKGJO_01996	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
EPNHKGJO_01997	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EPNHKGJO_01998	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EPNHKGJO_01999	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EPNHKGJO_02000	3.55e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPNHKGJO_02001	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
EPNHKGJO_02002	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EPNHKGJO_02003	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPNHKGJO_02004	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EPNHKGJO_02006	1.93e-53	-	-	-	-	-	-	-	-
EPNHKGJO_02007	1.09e-253	-	-	-	S	-	-	-	Bacterial EndoU nuclease
EPNHKGJO_02008	2.08e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
EPNHKGJO_02009	1.32e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EPNHKGJO_02010	1.9e-233	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
EPNHKGJO_02011	7.21e-282	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPNHKGJO_02012	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EPNHKGJO_02013	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
EPNHKGJO_02014	2.46e-183	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
EPNHKGJO_02015	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
EPNHKGJO_02016	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EPNHKGJO_02017	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
EPNHKGJO_02018	1.9e-68	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
EPNHKGJO_02019	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EPNHKGJO_02020	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPNHKGJO_02021	1.08e-140	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
EPNHKGJO_02022	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
EPNHKGJO_02025	2.67e-38	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
EPNHKGJO_02027	2.8e-49	-	-	-	S	-	-	-	Bacteriophage holin
EPNHKGJO_02028	3.46e-244	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
EPNHKGJO_02030	3.05e-299	-	-	-	S	-	-	-	damaged DNA binding
EPNHKGJO_02031	2.58e-71	-	-	-	S	-	-	-	YolD-like protein
EPNHKGJO_02033	1.48e-227	-	-	-	S	-	-	-	amine dehydrogenase activity
EPNHKGJO_02035	6.61e-31	-	-	-	-	-	-	-	-
EPNHKGJO_02036	6.39e-126	-	-	-	-	-	-	-	-
EPNHKGJO_02037	4.29e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EPNHKGJO_02038	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EPNHKGJO_02039	1.7e-92	yviE	-	-	-	-	-	-	-
EPNHKGJO_02040	3.8e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
EPNHKGJO_02041	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
EPNHKGJO_02042	3.5e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
EPNHKGJO_02043	1.06e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
EPNHKGJO_02044	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
EPNHKGJO_02045	9.99e-166	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
EPNHKGJO_02046	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
EPNHKGJO_02047	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EPNHKGJO_02048	1.77e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_02049	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPNHKGJO_02050	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EPNHKGJO_02051	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
EPNHKGJO_02052	2.68e-223	yvhJ	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_02053	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EPNHKGJO_02054	2.49e-298	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
EPNHKGJO_02055	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
EPNHKGJO_02056	2.02e-147	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
EPNHKGJO_02057	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
EPNHKGJO_02058	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EPNHKGJO_02059	1.63e-278	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
EPNHKGJO_02060	2.58e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPNHKGJO_02061	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EPNHKGJO_02062	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
EPNHKGJO_02063	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
EPNHKGJO_02064	3.26e-50	-	-	-	-	-	-	-	-
EPNHKGJO_02065	1.13e-218	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EPNHKGJO_02066	2.58e-275	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EPNHKGJO_02071	2.51e-45	-	-	-	S	-	-	-	Putative amidase domain
EPNHKGJO_02072	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EPNHKGJO_02073	2.5e-176	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EPNHKGJO_02074	8.14e-240	spsG	-	-	M	-	-	-	Spore Coat
EPNHKGJO_02075	8.63e-165	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
EPNHKGJO_02076	7.93e-271	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
EPNHKGJO_02077	8.17e-208	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
EPNHKGJO_02078	2.07e-281	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
EPNHKGJO_02079	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
EPNHKGJO_02080	8.08e-187	spsA	-	-	M	-	-	-	Spore Coat
EPNHKGJO_02081	7.3e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EPNHKGJO_02082	6.48e-78	ywdK	-	-	S	-	-	-	small membrane protein
EPNHKGJO_02083	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
EPNHKGJO_02084	9.23e-65	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
EPNHKGJO_02085	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
EPNHKGJO_02086	2.32e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EPNHKGJO_02087	1.34e-191	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
EPNHKGJO_02089	1.19e-143	ywdD	-	-	-	-	-	-	-
EPNHKGJO_02090	6.52e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
EPNHKGJO_02091	5.2e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
EPNHKGJO_02092	6.19e-39	ywdA	-	-	-	-	-	-	-
EPNHKGJO_02093	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
EPNHKGJO_02094	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_02095	3.96e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
EPNHKGJO_02096	2.13e-192	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
EPNHKGJO_02099	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
EPNHKGJO_02100	9.87e-238	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPNHKGJO_02101	1.98e-179	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
EPNHKGJO_02102	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
EPNHKGJO_02103	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
EPNHKGJO_02104	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
EPNHKGJO_02105	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
EPNHKGJO_02106	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EPNHKGJO_02107	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EPNHKGJO_02108	5.11e-49	ydaS	-	-	S	-	-	-	membrane
EPNHKGJO_02109	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
EPNHKGJO_02110	6.49e-290	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EPNHKGJO_02111	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
EPNHKGJO_02112	1.1e-154	ywcC	-	-	K	-	-	-	transcriptional regulator
EPNHKGJO_02114	7.41e-65	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
EPNHKGJO_02115	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPNHKGJO_02116	3.25e-144	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
EPNHKGJO_02117	4.22e-306	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
EPNHKGJO_02118	1.98e-245	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
EPNHKGJO_02119	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
EPNHKGJO_02120	2.03e-145	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EPNHKGJO_02121	2.99e-181	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EPNHKGJO_02122	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_02123	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EPNHKGJO_02124	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
EPNHKGJO_02125	5.87e-275	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
EPNHKGJO_02126	1.05e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
EPNHKGJO_02127	4.67e-279	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
EPNHKGJO_02128	1.99e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
EPNHKGJO_02129	5.66e-158	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
EPNHKGJO_02130	3.5e-309	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPNHKGJO_02131	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
EPNHKGJO_02132	5.64e-310	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_02133	9.07e-196	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
EPNHKGJO_02134	3.78e-216	gspA	-	-	M	-	-	-	General stress
EPNHKGJO_02135	5.31e-51	ywaF	-	-	S	-	-	-	Integral membrane protein
EPNHKGJO_02136	3.33e-82	ywaF	-	-	S	-	-	-	Integral membrane protein
EPNHKGJO_02137	2.15e-115	ywaE	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_02138	4.48e-297	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPNHKGJO_02139	9.14e-317	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
EPNHKGJO_02140	1.08e-115	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EPNHKGJO_02141	5.58e-64	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
EPNHKGJO_02142	3.96e-165	-	-	-	EGP	-	-	-	Permeases of the major facilitator superfamily
EPNHKGJO_02143	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
EPNHKGJO_02144	5.7e-210	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
EPNHKGJO_02145	1.27e-20	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
EPNHKGJO_02146	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPNHKGJO_02147	2.29e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
EPNHKGJO_02148	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPNHKGJO_02149	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EPNHKGJO_02150	3.97e-176	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNHKGJO_02151	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
EPNHKGJO_02152	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EPNHKGJO_02153	1.3e-49	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_02154	3.82e-157	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPNHKGJO_02155	2.16e-203	ytbE	-	-	S	-	-	-	reductase
EPNHKGJO_02156	1.37e-255	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
EPNHKGJO_02157	9.37e-21	ytcD	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_02158	8.75e-55	ytcD	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_02159	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPNHKGJO_02160	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EPNHKGJO_02161	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EPNHKGJO_02162	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
EPNHKGJO_02163	1.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
EPNHKGJO_02164	9.37e-142	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
EPNHKGJO_02165	5.74e-204	ytxC	-	-	S	-	-	-	YtxC-like family
EPNHKGJO_02167	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPNHKGJO_02168	6.64e-188	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
EPNHKGJO_02169	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_02170	3.39e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
EPNHKGJO_02171	2.08e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EPNHKGJO_02172	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EPNHKGJO_02174	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EPNHKGJO_02175	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
EPNHKGJO_02176	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EPNHKGJO_02177	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
EPNHKGJO_02178	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
EPNHKGJO_02179	4.35e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
EPNHKGJO_02180	4.56e-241	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
EPNHKGJO_02181	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
EPNHKGJO_02182	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
EPNHKGJO_02183	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EPNHKGJO_02184	7.07e-186	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
EPNHKGJO_02185	1.24e-280	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EPNHKGJO_02186	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
EPNHKGJO_02187	1.94e-218	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
EPNHKGJO_02188	7.39e-191	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
EPNHKGJO_02189	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
EPNHKGJO_02190	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
EPNHKGJO_02192	5.13e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
EPNHKGJO_02193	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
EPNHKGJO_02194	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
EPNHKGJO_02195	1.24e-260	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
EPNHKGJO_02196	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
EPNHKGJO_02197	1.22e-168	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPNHKGJO_02198	1.81e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EPNHKGJO_02199	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPNHKGJO_02200	1.47e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPNHKGJO_02201	2.45e-53	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EPNHKGJO_02202	1.55e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
EPNHKGJO_02203	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
EPNHKGJO_02204	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EPNHKGJO_02205	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
EPNHKGJO_02206	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EPNHKGJO_02207	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_02208	1.81e-175	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
EPNHKGJO_02209	1.74e-177	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
EPNHKGJO_02210	1.18e-225	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
EPNHKGJO_02212	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
EPNHKGJO_02213	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
EPNHKGJO_02214	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EPNHKGJO_02215	3.79e-273	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
EPNHKGJO_02216	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
EPNHKGJO_02217	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
EPNHKGJO_02218	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
EPNHKGJO_02219	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
EPNHKGJO_02220	2.65e-102	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
EPNHKGJO_02221	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_02222	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EPNHKGJO_02223	3.55e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
EPNHKGJO_02224	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
EPNHKGJO_02225	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EPNHKGJO_02226	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPNHKGJO_02227	1.65e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
EPNHKGJO_02229	9.64e-183	ysnF	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_02230	1.25e-102	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
EPNHKGJO_02232	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
EPNHKGJO_02233	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
EPNHKGJO_02234	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EPNHKGJO_02235	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EPNHKGJO_02236	7.43e-256	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EPNHKGJO_02237	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EPNHKGJO_02238	7.31e-148	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EPNHKGJO_02239	1.11e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
EPNHKGJO_02240	2.96e-285	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EPNHKGJO_02241	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EPNHKGJO_02242	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
EPNHKGJO_02243	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EPNHKGJO_02244	6.25e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
EPNHKGJO_02245	8.23e-117	ysxD	-	-	-	-	-	-	-
EPNHKGJO_02246	1.92e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EPNHKGJO_02247	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
EPNHKGJO_02248	7.63e-221	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EPNHKGJO_02249	5.87e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
EPNHKGJO_02250	3.7e-233	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
EPNHKGJO_02251	1.75e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
EPNHKGJO_02252	3.58e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
EPNHKGJO_02253	1.81e-65	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
EPNHKGJO_02254	1.13e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
EPNHKGJO_02255	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
EPNHKGJO_02256	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
EPNHKGJO_02257	1.46e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
EPNHKGJO_02258	1.59e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
EPNHKGJO_02259	1.73e-48	yfhS	-	-	-	-	-	-	-
EPNHKGJO_02260	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_02261	9.51e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
EPNHKGJO_02262	1.88e-63	ygaB	-	-	S	-	-	-	YgaB-like protein
EPNHKGJO_02263	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
EPNHKGJO_02264	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
EPNHKGJO_02265	3.61e-236	ygaE	-	-	S	-	-	-	Membrane
EPNHKGJO_02266	3.26e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
EPNHKGJO_02267	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
EPNHKGJO_02268	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
EPNHKGJO_02269	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
EPNHKGJO_02270	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
EPNHKGJO_02271	1.09e-205	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
EPNHKGJO_02272	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
EPNHKGJO_02273	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
EPNHKGJO_02274	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPNHKGJO_02275	1.91e-33	-	-	-	S	-	-	-	Ion transport 2 domain protein
EPNHKGJO_02276	1.75e-184	-	-	-	S	-	-	-	Ion transport 2 domain protein
EPNHKGJO_02277	4.91e-201	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
EPNHKGJO_02278	4.56e-167	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
EPNHKGJO_02279	3.64e-228	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPNHKGJO_02280	1.54e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
EPNHKGJO_02281	2.1e-221	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
EPNHKGJO_02282	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
EPNHKGJO_02283	8.71e-258	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
EPNHKGJO_02284	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
EPNHKGJO_02285	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
EPNHKGJO_02286	1.09e-123	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
EPNHKGJO_02287	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
EPNHKGJO_02288	1.12e-103	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
EPNHKGJO_02289	4.31e-82	yozB	-	-	S	ko:K08976	-	ko00000	Membrane
EPNHKGJO_02292	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
EPNHKGJO_02293	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
EPNHKGJO_02294	2.74e-271	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
EPNHKGJO_02295	2.3e-124	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
EPNHKGJO_02296	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EPNHKGJO_02297	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPNHKGJO_02298	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EPNHKGJO_02299	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EPNHKGJO_02300	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
EPNHKGJO_02301	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
EPNHKGJO_02302	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
EPNHKGJO_02303	1.92e-140	yodC	-	-	C	-	-	-	nitroreductase
EPNHKGJO_02304	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
EPNHKGJO_02305	3.27e-83	iolK	-	-	S	-	-	-	tautomerase
EPNHKGJO_02306	3.09e-288	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
EPNHKGJO_02307	3.94e-14	-	-	-	-	-	-	-	-
EPNHKGJO_02308	3.51e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
EPNHKGJO_02309	5.49e-206	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
EPNHKGJO_02310	1.85e-58	-	-	-	-	-	-	-	-
EPNHKGJO_02311	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
EPNHKGJO_02312	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
EPNHKGJO_02313	8.33e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPNHKGJO_02314	1.89e-309	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
EPNHKGJO_02316	6.12e-141	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EPNHKGJO_02317	1.09e-291	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
EPNHKGJO_02318	1.05e-263	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
EPNHKGJO_02319	4.94e-140	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EPNHKGJO_02320	5.42e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
EPNHKGJO_02321	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
EPNHKGJO_02322	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EPNHKGJO_02323	2.59e-264	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EPNHKGJO_02324	4.7e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
EPNHKGJO_02325	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EPNHKGJO_02326	4.57e-210	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
EPNHKGJO_02327	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
EPNHKGJO_02328	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
EPNHKGJO_02329	1.91e-42	yozC	-	-	-	-	-	-	-
EPNHKGJO_02330	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
EPNHKGJO_02331	1.83e-49	yocN	-	-	-	-	-	-	-
EPNHKGJO_02332	2.94e-55	yozN	-	-	-	-	-	-	-
EPNHKGJO_02333	1.5e-111	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
EPNHKGJO_02334	6.54e-40	-	-	-	-	-	-	-	-
EPNHKGJO_02335	4.29e-70	yocL	-	-	-	-	-	-	-
EPNHKGJO_02336	1.42e-107	yocK	-	-	T	-	-	-	general stress protein
EPNHKGJO_02337	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EPNHKGJO_02338	7.42e-172	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
EPNHKGJO_02339	4.95e-240	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
EPNHKGJO_02340	2.89e-175	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
EPNHKGJO_02341	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPNHKGJO_02342	2.37e-250	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_02343	5.67e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
EPNHKGJO_02344	3.06e-237	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
EPNHKGJO_02345	2.99e-119	yocC	-	-	-	-	-	-	-
EPNHKGJO_02346	2.39e-181	-	-	-	-	-	-	-	-
EPNHKGJO_02347	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
EPNHKGJO_02348	2.19e-140	-	-	-	L	-	-	-	Transposase
EPNHKGJO_02351	5.04e-87	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
EPNHKGJO_02353	5.52e-285	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
EPNHKGJO_02354	2.4e-277	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EPNHKGJO_02355	1.11e-41	-	-	-	-	-	-	-	-
EPNHKGJO_02356	1.01e-185	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
EPNHKGJO_02357	1.05e-154	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
EPNHKGJO_02358	1.14e-174	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPNHKGJO_02359	1.81e-224	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
EPNHKGJO_02360	2.87e-117	yjlB	-	-	S	-	-	-	Cupin domain
EPNHKGJO_02361	3.98e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
EPNHKGJO_02362	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
EPNHKGJO_02363	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
EPNHKGJO_02364	7.52e-315	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
EPNHKGJO_02365	2.08e-241	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
EPNHKGJO_02366	5.73e-240	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
EPNHKGJO_02367	1.53e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
EPNHKGJO_02368	1.34e-196	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNHKGJO_02369	1.37e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
EPNHKGJO_02370	2.23e-234	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
EPNHKGJO_02371	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
EPNHKGJO_02372	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
EPNHKGJO_02373	9.2e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EPNHKGJO_02374	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
EPNHKGJO_02375	2.38e-311	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
EPNHKGJO_02376	1.6e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
EPNHKGJO_02378	1.21e-53	-	-	-	S	-	-	-	YCII-related domain
EPNHKGJO_02379	1.26e-216	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
EPNHKGJO_02380	5.74e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
EPNHKGJO_02381	2.74e-139	yjqB	-	-	S	-	-	-	Pfam:DUF867
EPNHKGJO_02382	1.3e-203	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
EPNHKGJO_02383	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
EPNHKGJO_02384	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EPNHKGJO_02386	7.53e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
EPNHKGJO_02387	2.05e-139	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
EPNHKGJO_02391	5.95e-112	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EPNHKGJO_02392	4.78e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
EPNHKGJO_02393	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
EPNHKGJO_02394	0.0	yqbA	-	-	S	-	-	-	portal protein
EPNHKGJO_02395	9.88e-177	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
EPNHKGJO_02396	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
EPNHKGJO_02397	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
EPNHKGJO_02398	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
EPNHKGJO_02399	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
EPNHKGJO_02400	2.36e-100	xkdJ	-	-	-	-	-	-	-
EPNHKGJO_02401	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
EPNHKGJO_02402	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
EPNHKGJO_02403	3.34e-101	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
EPNHKGJO_02404	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
EPNHKGJO_02405	2.49e-149	xkdP	-	-	S	-	-	-	Lysin motif
EPNHKGJO_02406	9.42e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
EPNHKGJO_02407	1.24e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
EPNHKGJO_02408	3.82e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
EPNHKGJO_02409	3.6e-243	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EPNHKGJO_02410	6.25e-132	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
EPNHKGJO_02411	2.56e-55	-	-	-	-	-	-	-	-
EPNHKGJO_02412	5.43e-164	-	-	-	-	-	-	-	-
EPNHKGJO_02414	1.82e-12	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
EPNHKGJO_02415	2.71e-46	xhlA	-	-	S	-	-	-	Haemolysin XhlA
EPNHKGJO_02416	8.12e-53	xhlB	-	-	S	-	-	-	SPP1 phage holin
EPNHKGJO_02417	3.73e-208	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
EPNHKGJO_02418	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
EPNHKGJO_02419	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
EPNHKGJO_02420	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
EPNHKGJO_02421	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
EPNHKGJO_02422	2.36e-305	steT	-	-	E	ko:K03294	-	ko00000	amino acid
EPNHKGJO_02423	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
EPNHKGJO_02424	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EPNHKGJO_02425	5.21e-228	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
EPNHKGJO_02427	1.92e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPNHKGJO_02428	3.2e-176	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
EPNHKGJO_02429	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
EPNHKGJO_02430	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPNHKGJO_02431	3.02e-224	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPNHKGJO_02432	6.67e-237	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPNHKGJO_02433	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
EPNHKGJO_02435	2.26e-223	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
EPNHKGJO_02436	1.09e-253	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
EPNHKGJO_02437	1.2e-208	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EPNHKGJO_02438	8.44e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPNHKGJO_02439	9.43e-260	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
EPNHKGJO_02440	2.95e-204	ykgA	-	-	E	-	-	-	Amidinotransferase
EPNHKGJO_02441	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
EPNHKGJO_02442	8.15e-284	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPNHKGJO_02443	5.45e-13	-	-	-	-	-	-	-	-
EPNHKGJO_02444	3.25e-166	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
EPNHKGJO_02445	9.11e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
EPNHKGJO_02446	8.47e-127	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EPNHKGJO_02447	7.34e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
EPNHKGJO_02448	1.94e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
EPNHKGJO_02449	1.66e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EPNHKGJO_02450	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPNHKGJO_02451	6.52e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EPNHKGJO_02453	6.6e-91	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
EPNHKGJO_02454	1.21e-98	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
EPNHKGJO_02455	2.34e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
EPNHKGJO_02456	1.63e-114	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
EPNHKGJO_02457	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
EPNHKGJO_02458	1.42e-75	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
EPNHKGJO_02459	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EPNHKGJO_02460	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
EPNHKGJO_02461	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EPNHKGJO_02462	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EPNHKGJO_02463	2.11e-251	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
EPNHKGJO_02464	6.09e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EPNHKGJO_02465	2.59e-112	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EPNHKGJO_02466	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPNHKGJO_02467	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
EPNHKGJO_02468	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
EPNHKGJO_02469	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EPNHKGJO_02470	3.52e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPNHKGJO_02471	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
EPNHKGJO_02472	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
EPNHKGJO_02473	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EPNHKGJO_02474	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
EPNHKGJO_02475	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EPNHKGJO_02476	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EPNHKGJO_02477	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EPNHKGJO_02478	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EPNHKGJO_02479	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
EPNHKGJO_02480	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPNHKGJO_02481	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPNHKGJO_02482	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
EPNHKGJO_02483	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EPNHKGJO_02484	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EPNHKGJO_02485	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EPNHKGJO_02486	1.36e-285	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EPNHKGJO_02487	8.42e-236	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
EPNHKGJO_02488	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
EPNHKGJO_02489	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EPNHKGJO_02490	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
EPNHKGJO_02491	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EPNHKGJO_02492	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EPNHKGJO_02493	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EPNHKGJO_02494	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EPNHKGJO_02495	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EPNHKGJO_02496	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EPNHKGJO_02497	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
EPNHKGJO_02498	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EPNHKGJO_02499	7.32e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EPNHKGJO_02500	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EPNHKGJO_02501	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EPNHKGJO_02502	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPNHKGJO_02503	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EPNHKGJO_02504	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EPNHKGJO_02505	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EPNHKGJO_02506	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EPNHKGJO_02507	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
EPNHKGJO_02508	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
EPNHKGJO_02509	8.09e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EPNHKGJO_02510	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EPNHKGJO_02511	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
EPNHKGJO_02512	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EPNHKGJO_02513	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
EPNHKGJO_02514	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EPNHKGJO_02515	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EPNHKGJO_02516	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPNHKGJO_02517	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
EPNHKGJO_02518	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPNHKGJO_02519	2.69e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPNHKGJO_02520	4.39e-175	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPNHKGJO_02521	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EPNHKGJO_02522	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EPNHKGJO_02523	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
EPNHKGJO_02524	7.18e-185	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
EPNHKGJO_02525	1.53e-92	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
EPNHKGJO_02526	3.03e-168	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
EPNHKGJO_02527	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EPNHKGJO_02528	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
EPNHKGJO_02529	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
EPNHKGJO_02530	1.75e-180	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
EPNHKGJO_02531	2.31e-110	-	-	-	L	-	-	-	Tn3 transposase DDE domain
EPNHKGJO_02532	9.02e-182	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
EPNHKGJO_02533	6.62e-140	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPNHKGJO_02534	2.05e-178	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
EPNHKGJO_02535	5.02e-158	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
EPNHKGJO_02536	3.26e-81	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
EPNHKGJO_02537	1.35e-74	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
EPNHKGJO_02538	6.09e-65	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
EPNHKGJO_02539	1.31e-206	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
EPNHKGJO_02540	2.26e-142	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
EPNHKGJO_02541	2.16e-197	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EPNHKGJO_02542	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
EPNHKGJO_02543	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPNHKGJO_02544	1.28e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
EPNHKGJO_02545	1.41e-119	yisT	-	-	S	-	-	-	DinB family
EPNHKGJO_02546	8.57e-248	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
EPNHKGJO_02547	4.83e-231	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
EPNHKGJO_02548	4.04e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_02549	2.91e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
EPNHKGJO_02550	6.96e-152	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
EPNHKGJO_02551	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
EPNHKGJO_02552	4.29e-131	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
EPNHKGJO_02553	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
EPNHKGJO_02554	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
EPNHKGJO_02555	2.66e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EPNHKGJO_02556	2.2e-221	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
EPNHKGJO_02557	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
EPNHKGJO_02558	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
EPNHKGJO_02559	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
EPNHKGJO_02560	1e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
EPNHKGJO_02561	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
EPNHKGJO_02562	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
EPNHKGJO_02563	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
EPNHKGJO_02564	2.41e-62	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
EPNHKGJO_02565	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
EPNHKGJO_02566	4.67e-279	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EPNHKGJO_02567	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
EPNHKGJO_02568	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
EPNHKGJO_02569	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
EPNHKGJO_02570	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
EPNHKGJO_02571	7.04e-270	-	-	-	EGP	-	-	-	Transmembrane secretion effector
EPNHKGJO_02572	2.5e-259	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
EPNHKGJO_02573	4.36e-239	yhjM	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_02574	7.97e-162	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
EPNHKGJO_02575	4.22e-142	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
EPNHKGJO_02576	3.07e-204	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
EPNHKGJO_02577	5.43e-255	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
EPNHKGJO_02578	4.25e-271	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
EPNHKGJO_02579	8.09e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EPNHKGJO_02580	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
EPNHKGJO_02581	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
EPNHKGJO_02582	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
EPNHKGJO_02583	4.13e-78	yhjD	-	-	-	-	-	-	-
EPNHKGJO_02584	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
EPNHKGJO_02585	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPNHKGJO_02586	1.68e-55	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
EPNHKGJO_02587	1.16e-212	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
EPNHKGJO_02588	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
EPNHKGJO_02589	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
EPNHKGJO_02590	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_02591	8.24e-238	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
EPNHKGJO_02592	1.67e-120	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
EPNHKGJO_02593	7.16e-258	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
EPNHKGJO_02594	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
EPNHKGJO_02595	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
EPNHKGJO_02596	1.42e-248	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
EPNHKGJO_02597	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
EPNHKGJO_02598	1.4e-99	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
EPNHKGJO_02599	3.13e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
EPNHKGJO_02600	1.35e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EPNHKGJO_02601	9e-193	ybbH	-	-	K	-	-	-	transcriptional
EPNHKGJO_02602	1.21e-302	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_02603	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
EPNHKGJO_02604	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
EPNHKGJO_02605	1.84e-299	ybbC	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_02606	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
EPNHKGJO_02607	2.43e-214	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
EPNHKGJO_02608	4.77e-225	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_02609	3.51e-228	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_02610	4.31e-179	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
EPNHKGJO_02611	2.34e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
EPNHKGJO_02612	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
EPNHKGJO_02613	1.56e-08	-	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
EPNHKGJO_02614	3.07e-98	-	-	-	-	-	-	-	-
EPNHKGJO_02615	1.6e-108	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
EPNHKGJO_02616	4.75e-57	yxiJ	-	-	S	-	-	-	YxiJ-like protein
EPNHKGJO_02619	2.48e-274	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
EPNHKGJO_02620	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EPNHKGJO_02621	1.8e-290	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
EPNHKGJO_02622	3.59e-141	-	-	-	-	-	-	-	-
EPNHKGJO_02623	1.72e-177	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
EPNHKGJO_02624	3.06e-184	bglS	-	-	M	-	-	-	licheninase activity
EPNHKGJO_02625	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
EPNHKGJO_02626	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
EPNHKGJO_02627	2.28e-63	yxiS	-	-	-	-	-	-	-
EPNHKGJO_02628	4.89e-132	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
EPNHKGJO_02629	3.47e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPNHKGJO_02631	3.93e-47	XK26_06135	-	-	D	-	-	-	Plasmid recombination enzyme
EPNHKGJO_02632	4.1e-45	XK26_06135	-	-	D	-	-	-	Plasmid recombination enzyme
EPNHKGJO_02633	2.06e-92	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPNHKGJO_02634	4.21e-23	-	-	-	S	-	-	-	Protein conserved in bacteria
EPNHKGJO_02635	5.01e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF1430)
EPNHKGJO_02637	1.94e-104	-	-	-	L	-	-	-	DNA-invertase Bin3
EPNHKGJO_02638	1.74e-189	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
EPNHKGJO_02639	0.0	blaR1	-	-	KTV	ko:K02172	ko01501,map01501	ko00000,ko00001,ko00002,ko01002,ko01504	Regulatory protein BlaR1
EPNHKGJO_02640	1.02e-80	blaI	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
EPNHKGJO_02641	1.26e-138	-	-	-	L	-	-	-	Resolvase, N terminal domain
EPNHKGJO_02642	3.24e-143	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
EPNHKGJO_02643	3.03e-199	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
EPNHKGJO_02644	2.33e-198	-	3.6.1.3	-	S	ko:K07132	-	ko00000,ko01000	AAA domain
EPNHKGJO_02645	3.61e-33	-	-	-	T	-	-	-	Domain of unknown function (DUF4062)
EPNHKGJO_02646	4.71e-74	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
EPNHKGJO_02647	1.27e-126	cadD	-	-	P	-	-	-	Cadmium resistance transporter
EPNHKGJO_02648	8.8e-28	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
EPNHKGJO_02649	1.52e-103	-	-	-	S	-	-	-	Protein of unknown function, DUF536
EPNHKGJO_02651	2.82e-41	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
EPNHKGJO_02652	1.94e-152	-	-	-	L	-	-	-	Initiator Replication protein
EPNHKGJO_02653	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
EPNHKGJO_02654	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
EPNHKGJO_02655	1.2e-122	-	-	-	M	-	-	-	FR47-like protein
EPNHKGJO_02656	3.58e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
EPNHKGJO_02658	4.77e-68	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
EPNHKGJO_02662	2.38e-24	-	-	-	S	-	-	-	Transcriptional activator RinB
EPNHKGJO_02663	2.46e-57	-	-	-	S	-	-	-	peptidase activity
EPNHKGJO_02664	2.59e-28	yleF	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_02665	3.59e-203	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
EPNHKGJO_02666	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
EPNHKGJO_02667	7.71e-167	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EPNHKGJO_02668	4.86e-150	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EPNHKGJO_02669	7.78e-33	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EPNHKGJO_02670	1.41e-115	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EPNHKGJO_02671	6.32e-275	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
EPNHKGJO_02672	1.5e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
EPNHKGJO_02673	2.88e-111	yxjI	-	-	S	-	-	-	LURP-one-related
EPNHKGJO_02676	7.76e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
EPNHKGJO_02677	7.4e-146	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
EPNHKGJO_02678	1.37e-258	-	-	-	T	-	-	-	Signal transduction histidine kinase
EPNHKGJO_02679	7.69e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
EPNHKGJO_02680	4.26e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
EPNHKGJO_02681	2.35e-98	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
EPNHKGJO_02682	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPNHKGJO_02683	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPNHKGJO_02684	1.12e-209	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
EPNHKGJO_02685	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPNHKGJO_02686	6.16e-198	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
EPNHKGJO_02688	0.0	-	-	-	O	-	-	-	Peptidase family M48
EPNHKGJO_02689	3.8e-308	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
EPNHKGJO_02690	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
EPNHKGJO_02691	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
EPNHKGJO_02692	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
EPNHKGJO_02693	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
EPNHKGJO_02694	2.09e-123	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPNHKGJO_02695	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
EPNHKGJO_02696	1.06e-123	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPNHKGJO_02697	1.58e-52	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
EPNHKGJO_02698	6.66e-39	-	-	-	-	-	-	-	-
EPNHKGJO_02699	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
EPNHKGJO_02700	1.17e-188	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_02701	2.98e-126	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EPNHKGJO_02702	1.64e-248	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
EPNHKGJO_02703	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
EPNHKGJO_02704	1.54e-143	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
EPNHKGJO_02705	8.94e-28	yxzF	-	-	-	-	-	-	-
EPNHKGJO_02706	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
EPNHKGJO_02707	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
EPNHKGJO_02709	1.8e-45	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
EPNHKGJO_02710	6e-53	-	-	-	-	-	-	-	-
EPNHKGJO_02711	2.75e-244	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
EPNHKGJO_02712	4.39e-05	-	-	-	S	-	-	-	Nitrate reductase delta subunit
EPNHKGJO_02713	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
EPNHKGJO_02714	5.92e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
EPNHKGJO_02715	2.47e-47	ydzE	-	-	EG	-	-	-	spore germination
EPNHKGJO_02716	1.26e-208	-	-	-	K	-	-	-	AraC-like ligand binding domain
EPNHKGJO_02717	3.23e-220	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EPNHKGJO_02718	8.83e-208	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
EPNHKGJO_02719	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPNHKGJO_02720	4.7e-197	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
EPNHKGJO_02721	3.19e-132	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
EPNHKGJO_02722	2.46e-140	-	-	-	-	-	-	-	-
EPNHKGJO_02724	3.3e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
EPNHKGJO_02725	6e-111	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
EPNHKGJO_02726	1.56e-195	ydeK	-	-	EG	-	-	-	-transporter
EPNHKGJO_02727	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPNHKGJO_02728	8.69e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
EPNHKGJO_02729	2.03e-136	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
EPNHKGJO_02730	5.22e-75	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
EPNHKGJO_02731	1.96e-195	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
EPNHKGJO_02732	3e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
EPNHKGJO_02733	2.04e-293	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EPNHKGJO_02734	1.51e-95	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
EPNHKGJO_02735	7.12e-185	-	-	-	J	-	-	-	GNAT acetyltransferase
EPNHKGJO_02736	1.62e-202	-	-	-	EG	-	-	-	EamA-like transporter family
EPNHKGJO_02737	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPNHKGJO_02738	1.64e-148	ydfE	-	-	S	-	-	-	Flavin reductase like domain
EPNHKGJO_02739	8.69e-158	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
EPNHKGJO_02740	6.51e-103	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EPNHKGJO_02742	2.64e-249	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_02743	1.33e-141	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPNHKGJO_02744	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
EPNHKGJO_02745	3.77e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
EPNHKGJO_02746	9.72e-186	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
EPNHKGJO_02747	6.73e-13	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
EPNHKGJO_02752	3.62e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
EPNHKGJO_02753	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
EPNHKGJO_02754	8.27e-163	yebC	-	-	K	-	-	-	transcriptional regulatory protein
EPNHKGJO_02755	6.81e-67	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPNHKGJO_02756	5.73e-209	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
EPNHKGJO_02757	3.78e-271	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EPNHKGJO_02758	9.81e-200	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
EPNHKGJO_02759	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
EPNHKGJO_02760	1.12e-288	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
EPNHKGJO_02761	5.86e-122	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
EPNHKGJO_02762	4.99e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
EPNHKGJO_02763	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
EPNHKGJO_02764	5.59e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EPNHKGJO_02765	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
EPNHKGJO_02766	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
EPNHKGJO_02767	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
EPNHKGJO_02768	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
EPNHKGJO_02769	1.52e-207	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
EPNHKGJO_02770	1.06e-186	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
EPNHKGJO_02771	6.84e-185	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
EPNHKGJO_02772	2.05e-156	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EPNHKGJO_02773	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
EPNHKGJO_02774	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
EPNHKGJO_02775	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
EPNHKGJO_02776	8.35e-163	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
EPNHKGJO_02777	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
EPNHKGJO_02778	9.61e-208	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
EPNHKGJO_02779	2.58e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EPNHKGJO_02780	5.8e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
EPNHKGJO_02781	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EPNHKGJO_02782	1.53e-35	-	-	-	-	-	-	-	-
EPNHKGJO_02783	5.63e-251	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EPNHKGJO_02784	1.32e-184	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
EPNHKGJO_02785	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EPNHKGJO_02786	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EPNHKGJO_02787	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_02788	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
EPNHKGJO_02789	4.77e-130	yvkB	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_02790	5.24e-296	yvkA	-	-	P	-	-	-	-transporter
EPNHKGJO_02791	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPNHKGJO_02792	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
EPNHKGJO_02793	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
EPNHKGJO_02794	1.1e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EPNHKGJO_02795	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
EPNHKGJO_02796	3.23e-75	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
EPNHKGJO_02797	1.31e-184	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
EPNHKGJO_02798	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EPNHKGJO_02799	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EPNHKGJO_02800	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPNHKGJO_02801	2.46e-67	-	-	-	-	-	-	-	-
EPNHKGJO_02802	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
EPNHKGJO_02803	6.02e-90	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
EPNHKGJO_02804	2.21e-313	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EPNHKGJO_02805	9.77e-71	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
EPNHKGJO_02806	7.08e-85	hxlR	-	-	K	-	-	-	transcriptional
EPNHKGJO_02807	9.34e-136	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
EPNHKGJO_02808	1.32e-125	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
EPNHKGJO_02809	9.46e-163	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
EPNHKGJO_02810	1.71e-72	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
EPNHKGJO_02811	1e-93	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
EPNHKGJO_02812	4.78e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
EPNHKGJO_02813	8.26e-312	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EPNHKGJO_02814	1.92e-26	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EPNHKGJO_02815	1.01e-68	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
EPNHKGJO_02816	4.37e-56	yckC	-	-	S	-	-	-	membrane
EPNHKGJO_02818	6.23e-186	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
EPNHKGJO_02819	5.79e-147	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
EPNHKGJO_02820	2.26e-123	yciC	-	-	S	-	-	-	GTPases (G3E family)
EPNHKGJO_02821	2.72e-141	yciC	-	-	S	-	-	-	GTPases (G3E family)
EPNHKGJO_02822	1.47e-131	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
EPNHKGJO_02823	2.47e-221	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
EPNHKGJO_02824	1.11e-282	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
EPNHKGJO_02825	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
EPNHKGJO_02826	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPNHKGJO_02827	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EPNHKGJO_02828	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
EPNHKGJO_02829	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
EPNHKGJO_02830	1.93e-241	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
EPNHKGJO_02831	2.95e-203	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
EPNHKGJO_02832	2.41e-184	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
EPNHKGJO_02833	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
EPNHKGJO_02834	1.12e-287	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
EPNHKGJO_02835	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPNHKGJO_02836	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
EPNHKGJO_02837	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
EPNHKGJO_02838	7.76e-187	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
EPNHKGJO_02839	6.64e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
EPNHKGJO_02840	2.05e-230	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
EPNHKGJO_02841	1.45e-183	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
EPNHKGJO_02842	4.28e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EPNHKGJO_02843	3.46e-111	tmrB	-	-	S	-	-	-	AAA domain
EPNHKGJO_02844	3.03e-190	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EPNHKGJO_02845	1.03e-120	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
EPNHKGJO_02846	2.1e-193	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
EPNHKGJO_02847	2.07e-192	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
EPNHKGJO_02848	1.44e-140	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
EPNHKGJO_02849	6.13e-100	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EPNHKGJO_02850	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
EPNHKGJO_02851	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
EPNHKGJO_02852	2.93e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
EPNHKGJO_02853	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EPNHKGJO_02854	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EPNHKGJO_02855	5.26e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EPNHKGJO_02856	1.24e-314	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
EPNHKGJO_02857	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EPNHKGJO_02858	2.45e-230	yaaC	-	-	S	-	-	-	YaaC-like Protein
EPNHKGJO_02859	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
EPNHKGJO_02860	2.29e-192	-	-	-	S	-	-	-	membrane
EPNHKGJO_02861	1.38e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
EPNHKGJO_02862	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
EPNHKGJO_02863	0.0	-	-	-	I	-	-	-	PLD-like domain
EPNHKGJO_02864	1.28e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
EPNHKGJO_02865	2.32e-152	yrzF	-	-	T	-	-	-	serine threonine protein kinase
EPNHKGJO_02866	2.77e-248	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
EPNHKGJO_02867	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
EPNHKGJO_02868	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
EPNHKGJO_02869	1.64e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EPNHKGJO_02870	3.72e-238	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EPNHKGJO_02871	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
EPNHKGJO_02872	2.46e-247	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EPNHKGJO_02873	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EPNHKGJO_02874	1.24e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
EPNHKGJO_02875	2.95e-96	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
EPNHKGJO_02876	1.67e-142	yrbG	-	-	S	-	-	-	membrane
EPNHKGJO_02877	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPNHKGJO_02878	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
EPNHKGJO_02879	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EPNHKGJO_02880	6.51e-114	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
EPNHKGJO_02881	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
EPNHKGJO_02882	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
EPNHKGJO_02883	1.46e-117	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPNHKGJO_02884	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPNHKGJO_02885	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EPNHKGJO_02886	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
EPNHKGJO_02888	3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
EPNHKGJO_02889	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EPNHKGJO_02890	3.96e-177	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EPNHKGJO_02891	2e-302	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EPNHKGJO_02892	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_02893	1.87e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
EPNHKGJO_02894	1.19e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EPNHKGJO_02895	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
EPNHKGJO_02896	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EPNHKGJO_02897	2.79e-105	yrrD	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_02898	8.4e-42	yrzR	-	-	-	-	-	-	-
EPNHKGJO_02899	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
EPNHKGJO_02900	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPNHKGJO_02901	9.28e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPNHKGJO_02902	1.05e-186	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
EPNHKGJO_02903	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
EPNHKGJO_02904	2.42e-239	yrrI	-	-	S	-	-	-	AI-2E family transporter
EPNHKGJO_02905	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EPNHKGJO_02906	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
EPNHKGJO_02907	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EPNHKGJO_02908	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
EPNHKGJO_02909	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EPNHKGJO_02910	1.4e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
EPNHKGJO_02911	6.57e-224	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
EPNHKGJO_02912	3.8e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
EPNHKGJO_02913	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
EPNHKGJO_02914	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPNHKGJO_02915	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
EPNHKGJO_02916	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
EPNHKGJO_02917	8.52e-37	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
EPNHKGJO_02918	7.23e-155	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
EPNHKGJO_02919	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPNHKGJO_02920	7.04e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
EPNHKGJO_02921	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
EPNHKGJO_02922	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
EPNHKGJO_02923	2.46e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
EPNHKGJO_02924	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
EPNHKGJO_02925	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
EPNHKGJO_02927	1.96e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
EPNHKGJO_02929	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
EPNHKGJO_02930	5.86e-122	yrhH	-	-	Q	-	-	-	methyltransferase
EPNHKGJO_02931	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
EPNHKGJO_02932	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
EPNHKGJO_02933	4.27e-59	yrhK	-	-	S	-	-	-	YrhK-like protein
EPNHKGJO_02934	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
EPNHKGJO_02935	7.09e-191	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
EPNHKGJO_02936	9.97e-114	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPNHKGJO_02937	5.9e-194	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
EPNHKGJO_02938	1.88e-135	yrhP	-	-	E	-	-	-	LysE type translocator
EPNHKGJO_02939	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
EPNHKGJO_02940	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
EPNHKGJO_02941	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
EPNHKGJO_02942	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
EPNHKGJO_02943	2.79e-166	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
EPNHKGJO_02944	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
EPNHKGJO_02945	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
EPNHKGJO_02946	2.63e-115	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
EPNHKGJO_02947	6.28e-249	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
EPNHKGJO_02948	2.32e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
EPNHKGJO_02949	3.79e-31	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
EPNHKGJO_02950	3.26e-72	-	-	-	L	-	-	-	transposase activity
EPNHKGJO_02951	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
EPNHKGJO_02952	7.55e-59	orfX1	-	-	L	-	-	-	Transposase
EPNHKGJO_02953	5.6e-173	-	-	-	L	-	-	-	Integrase core domain
EPNHKGJO_02955	1.29e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1381)
EPNHKGJO_02956	1.56e-133	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPNHKGJO_02957	2.25e-45	yvkN	-	-	-	-	-	-	-
EPNHKGJO_02958	8.09e-65	yvlA	-	-	-	-	-	-	-
EPNHKGJO_02959	9.59e-220	yvlB	-	-	S	-	-	-	Putative adhesin
EPNHKGJO_02960	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
EPNHKGJO_02961	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
EPNHKGJO_02962	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
EPNHKGJO_02963	8.46e-112	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EPNHKGJO_02964	8.35e-176	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
EPNHKGJO_02965	3.49e-290	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
EPNHKGJO_02966	7.73e-109	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EPNHKGJO_02967	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
EPNHKGJO_02968	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
EPNHKGJO_02969	2.58e-167	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EPNHKGJO_02970	2.51e-281	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EPNHKGJO_02971	1.47e-216	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EPNHKGJO_02972	1.29e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EPNHKGJO_02973	3.05e-210	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
EPNHKGJO_02974	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EPNHKGJO_02975	5.94e-118	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
EPNHKGJO_02976	3.15e-153	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
EPNHKGJO_02977	2.49e-178	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
EPNHKGJO_02978	2.42e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EPNHKGJO_02979	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EPNHKGJO_02980	1.74e-290	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EPNHKGJO_02981	1.17e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
EPNHKGJO_02982	1.2e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPNHKGJO_02983	2.67e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EPNHKGJO_02984	5.63e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EPNHKGJO_02985	3.05e-145	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
EPNHKGJO_02986	3.53e-169	-	-	-	-	-	-	-	-
EPNHKGJO_02987	0.0	-	-	-	-	-	-	-	-
EPNHKGJO_02989	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
EPNHKGJO_02990	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
EPNHKGJO_02991	4.38e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
EPNHKGJO_02992	1.18e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EPNHKGJO_02993	9.76e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EPNHKGJO_02994	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
EPNHKGJO_02995	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
EPNHKGJO_02996	1.04e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
EPNHKGJO_02997	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
EPNHKGJO_02998	8.02e-183	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
EPNHKGJO_02999	2.2e-42	-	-	-	-	-	-	-	-
EPNHKGJO_03000	3.69e-169	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_03001	1.96e-251	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
EPNHKGJO_03002	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_03003	8.99e-29	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
EPNHKGJO_03004	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
EPNHKGJO_03005	2.32e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPNHKGJO_03006	5.3e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
EPNHKGJO_03007	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
EPNHKGJO_03008	3.2e-70	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
EPNHKGJO_03009	3.11e-136	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
EPNHKGJO_03010	1.04e-219	yvdE	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_03011	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
EPNHKGJO_03012	3.44e-301	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
EPNHKGJO_03013	1.09e-44	-	-	-	S	-	-	-	exonuclease activity
EPNHKGJO_03014	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
EPNHKGJO_03015	0.0	ylaA	-	-	-	-	-	-	-
EPNHKGJO_03016	1.18e-55	ylaB	-	-	-	-	-	-	-
EPNHKGJO_03017	2.93e-114	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPNHKGJO_03019	9.96e-57	ylaE	-	-	-	-	-	-	-
EPNHKGJO_03020	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
EPNHKGJO_03021	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
EPNHKGJO_03022	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
EPNHKGJO_03023	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03024	1.64e-124	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPNHKGJO_03025	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
EPNHKGJO_03026	1.09e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EPNHKGJO_03027	1e-218	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
EPNHKGJO_03028	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
EPNHKGJO_03029	3.2e-267	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
EPNHKGJO_03030	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EPNHKGJO_03031	2.44e-213	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EPNHKGJO_03032	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EPNHKGJO_03033	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EPNHKGJO_03034	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EPNHKGJO_03035	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EPNHKGJO_03036	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EPNHKGJO_03037	9.56e-211	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
EPNHKGJO_03038	1.88e-80	ylbA	-	-	S	-	-	-	YugN-like family
EPNHKGJO_03039	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
EPNHKGJO_03040	4.39e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
EPNHKGJO_03041	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
EPNHKGJO_03042	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
EPNHKGJO_03043	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
EPNHKGJO_03044	5.1e-51	ylbG	-	-	S	-	-	-	UPF0298 protein
EPNHKGJO_03045	9.66e-123	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
EPNHKGJO_03046	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EPNHKGJO_03047	6.41e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
EPNHKGJO_03048	2.99e-175	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
EPNHKGJO_03049	4.52e-238	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
EPNHKGJO_03050	5.94e-301	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
EPNHKGJO_03052	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
EPNHKGJO_03053	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
EPNHKGJO_03054	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EPNHKGJO_03055	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
EPNHKGJO_03056	5.12e-211	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPNHKGJO_03057	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EPNHKGJO_03058	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
EPNHKGJO_03059	4.76e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EPNHKGJO_03060	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
EPNHKGJO_03061	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
EPNHKGJO_03062	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
EPNHKGJO_03063	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPNHKGJO_03064	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPNHKGJO_03065	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EPNHKGJO_03066	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
EPNHKGJO_03067	9.03e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EPNHKGJO_03068	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
EPNHKGJO_03069	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EPNHKGJO_03070	6.39e-142	ylxW	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03071	1.23e-149	ylxX	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03072	1.54e-75	sbp	-	-	S	-	-	-	small basic protein
EPNHKGJO_03073	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EPNHKGJO_03074	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EPNHKGJO_03075	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
EPNHKGJO_03076	1.21e-218	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EPNHKGJO_03077	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPNHKGJO_03078	1.55e-177	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPNHKGJO_03079	1.1e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EPNHKGJO_03080	1.95e-316	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
EPNHKGJO_03081	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
EPNHKGJO_03082	1.25e-201	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
EPNHKGJO_03083	9.03e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EPNHKGJO_03084	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EPNHKGJO_03085	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
EPNHKGJO_03086	1.49e-178	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
EPNHKGJO_03087	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
EPNHKGJO_03088	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EPNHKGJO_03089	1.58e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
EPNHKGJO_03090	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EPNHKGJO_03091	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EPNHKGJO_03092	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EPNHKGJO_03093	1.3e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
EPNHKGJO_03094	7.29e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
EPNHKGJO_03095	4.86e-316	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EPNHKGJO_03096	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
EPNHKGJO_03097	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
EPNHKGJO_03098	6.12e-182	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EPNHKGJO_03099	7.36e-222	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EPNHKGJO_03100	6.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EPNHKGJO_03101	8.96e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPNHKGJO_03102	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
EPNHKGJO_03103	1.04e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
EPNHKGJO_03104	1.25e-283	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
EPNHKGJO_03105	1.59e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
EPNHKGJO_03106	3.56e-186	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
EPNHKGJO_03107	1.02e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
EPNHKGJO_03108	7.63e-107	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
EPNHKGJO_03109	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
EPNHKGJO_03110	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
EPNHKGJO_03111	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
EPNHKGJO_03112	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
EPNHKGJO_03113	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
EPNHKGJO_03114	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EPNHKGJO_03115	5.98e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EPNHKGJO_03116	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPNHKGJO_03117	4.8e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPNHKGJO_03118	3.13e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EPNHKGJO_03119	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPNHKGJO_03120	2.16e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EPNHKGJO_03121	3.54e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
EPNHKGJO_03122	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
EPNHKGJO_03123	1.37e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EPNHKGJO_03124	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
EPNHKGJO_03125	4.7e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
EPNHKGJO_03126	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
EPNHKGJO_03127	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03128	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
EPNHKGJO_03129	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
EPNHKGJO_03130	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
EPNHKGJO_03131	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EPNHKGJO_03132	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EPNHKGJO_03133	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EPNHKGJO_03134	3.09e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
EPNHKGJO_03135	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
EPNHKGJO_03136	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPNHKGJO_03137	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EPNHKGJO_03138	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
EPNHKGJO_03139	2.28e-225	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EPNHKGJO_03140	1.34e-160	-	-	-	S	-	-	-	Phosphotransferase enzyme family
EPNHKGJO_03141	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EPNHKGJO_03142	3.95e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPNHKGJO_03143	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
EPNHKGJO_03144	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
EPNHKGJO_03145	9.77e-80	ylqD	-	-	S	-	-	-	YlqD protein
EPNHKGJO_03146	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EPNHKGJO_03147	9.8e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
EPNHKGJO_03148	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EPNHKGJO_03149	2.83e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EPNHKGJO_03150	1.18e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPNHKGJO_03151	0.0	ylqG	-	-	-	-	-	-	-
EPNHKGJO_03152	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
EPNHKGJO_03153	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EPNHKGJO_03154	6.23e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EPNHKGJO_03155	2.1e-214	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
EPNHKGJO_03156	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPNHKGJO_03157	4.47e-313	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EPNHKGJO_03158	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
EPNHKGJO_03159	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EPNHKGJO_03160	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EPNHKGJO_03161	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EPNHKGJO_03162	2.3e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EPNHKGJO_03163	2.52e-97	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
EPNHKGJO_03164	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
EPNHKGJO_03165	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
EPNHKGJO_03166	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EPNHKGJO_03167	1.11e-143	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
EPNHKGJO_03168	1.22e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EPNHKGJO_03169	1.03e-90	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
EPNHKGJO_03170	2.93e-83	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
EPNHKGJO_03171	2.21e-312	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
EPNHKGJO_03172	3.28e-95	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
EPNHKGJO_03173	2.1e-177	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
EPNHKGJO_03174	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
EPNHKGJO_03175	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EPNHKGJO_03176	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EPNHKGJO_03177	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
EPNHKGJO_03178	5.3e-135	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
EPNHKGJO_03179	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
EPNHKGJO_03180	1.06e-49	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
EPNHKGJO_03181	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
EPNHKGJO_03182	2.74e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EPNHKGJO_03183	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EPNHKGJO_03184	1.62e-255	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
EPNHKGJO_03185	1.49e-198	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
EPNHKGJO_03186	2.58e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EPNHKGJO_03187	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
EPNHKGJO_03188	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
EPNHKGJO_03189	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EPNHKGJO_03190	1.36e-111	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EPNHKGJO_03191	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPNHKGJO_03192	6.62e-99	ylxL	-	-	-	-	-	-	-
EPNHKGJO_03193	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
EPNHKGJO_03194	1.39e-201	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EPNHKGJO_03195	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
EPNHKGJO_03196	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EPNHKGJO_03197	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPNHKGJO_03198	5.77e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
EPNHKGJO_03199	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EPNHKGJO_03200	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
EPNHKGJO_03201	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EPNHKGJO_03202	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPNHKGJO_03203	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
EPNHKGJO_03204	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
EPNHKGJO_03205	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
EPNHKGJO_03206	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
EPNHKGJO_03207	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EPNHKGJO_03208	1.58e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
EPNHKGJO_03209	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EPNHKGJO_03210	4.96e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EPNHKGJO_03211	3.84e-231	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
EPNHKGJO_03212	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EPNHKGJO_03213	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EPNHKGJO_03214	6.89e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
EPNHKGJO_03215	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
EPNHKGJO_03216	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
EPNHKGJO_03217	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
EPNHKGJO_03218	4.73e-140	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EPNHKGJO_03219	1.66e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPNHKGJO_03220	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
EPNHKGJO_03221	1.57e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPNHKGJO_03222	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPNHKGJO_03223	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
EPNHKGJO_03224	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
EPNHKGJO_03225	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
EPNHKGJO_03226	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_03227	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_03228	3.17e-297	albE	-	-	S	-	-	-	Peptidase M16
EPNHKGJO_03229	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
EPNHKGJO_03230	4.27e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EPNHKGJO_03231	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
EPNHKGJO_03232	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
EPNHKGJO_03233	2.29e-172	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
EPNHKGJO_03234	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPNHKGJO_03235	3.56e-298	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
EPNHKGJO_03236	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EPNHKGJO_03237	2.82e-280	pbpX	-	-	V	-	-	-	Beta-lactamase
EPNHKGJO_03238	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
EPNHKGJO_03239	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
EPNHKGJO_03240	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
EPNHKGJO_03241	3.38e-252	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EPNHKGJO_03242	5.89e-278	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EPNHKGJO_03243	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EPNHKGJO_03244	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
EPNHKGJO_03245	5.83e-118	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
EPNHKGJO_03246	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EPNHKGJO_03247	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EPNHKGJO_03248	6.4e-90	-	-	-	S	-	-	-	Regulatory protein YrvL
EPNHKGJO_03249	5.38e-125	ymcC	-	-	S	-	-	-	Membrane
EPNHKGJO_03250	4.14e-134	pksA	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_03251	8.03e-81	ymzB	-	-	-	-	-	-	-
EPNHKGJO_03252	1.88e-207	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
EPNHKGJO_03253	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
EPNHKGJO_03255	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
EPNHKGJO_03256	5.98e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
EPNHKGJO_03257	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
EPNHKGJO_03258	1.21e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
EPNHKGJO_03260	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
EPNHKGJO_03261	9.69e-224	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EPNHKGJO_03262	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EPNHKGJO_03263	1.63e-31	-	-	-	-	-	-	-	-
EPNHKGJO_03264	1.2e-30	ymzA	-	-	-	-	-	-	-
EPNHKGJO_03265	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
EPNHKGJO_03266	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPNHKGJO_03267	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPNHKGJO_03268	2.24e-141	-	-	-	-	-	-	-	-
EPNHKGJO_03269	2.72e-148	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
EPNHKGJO_03270	3.46e-123	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
EPNHKGJO_03272	5.1e-123	-	-	-	-	-	-	-	-
EPNHKGJO_03277	1.74e-13	-	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_03278	2.2e-19	-	-	-	-	-	-	-	-
EPNHKGJO_03280	1.62e-242	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
EPNHKGJO_03281	5.52e-196	-	-	-	S	-	-	-	Bacterial EndoU nuclease
EPNHKGJO_03282	2.03e-29	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
EPNHKGJO_03283	3.04e-159	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
EPNHKGJO_03284	1.65e-43	xhlB	-	-	S	-	-	-	SPP1 phage holin
EPNHKGJO_03285	1.7e-36	xhlA	-	-	S	-	-	-	Haemolysin XhlA
EPNHKGJO_03286	4.58e-193	xepA	-	-	-	-	-	-	-
EPNHKGJO_03287	3.44e-26	-	-	-	-	-	-	-	-
EPNHKGJO_03288	4.65e-60	xkdW	-	-	S	-	-	-	XkdW protein
EPNHKGJO_03289	9.95e-192	-	-	-	-	-	-	-	-
EPNHKGJO_03290	1.33e-48	-	-	-	-	-	-	-	-
EPNHKGJO_03291	9.55e-127	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
EPNHKGJO_03292	2.14e-235	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EPNHKGJO_03293	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
EPNHKGJO_03294	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
EPNHKGJO_03295	8.3e-274	xylR	-	-	GK	-	-	-	ROK family
EPNHKGJO_03296	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
EPNHKGJO_03297	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
EPNHKGJO_03298	9.98e-183	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPNHKGJO_03299	1.28e-226	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
EPNHKGJO_03300	9.78e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNHKGJO_03301	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
EPNHKGJO_03302	1.09e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
EPNHKGJO_03303	7.43e-93	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPNHKGJO_03305	6.83e-288	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
EPNHKGJO_03307	2.43e-303	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPNHKGJO_03308	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
EPNHKGJO_03309	2.22e-112	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
EPNHKGJO_03310	2.63e-77	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
EPNHKGJO_03311	4.59e-248	yqkA	-	-	K	-	-	-	GrpB protein
EPNHKGJO_03312	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
EPNHKGJO_03313	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
EPNHKGJO_03314	3.25e-222	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
EPNHKGJO_03315	2.69e-25	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
EPNHKGJO_03316	4.4e-216	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
EPNHKGJO_03317	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
EPNHKGJO_03318	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
EPNHKGJO_03319	4.16e-280	yqxK	-	-	L	-	-	-	DNA helicase
EPNHKGJO_03320	1.29e-76	ansR	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_03321	1.46e-237	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
EPNHKGJO_03322	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
EPNHKGJO_03323	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
EPNHKGJO_03324	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
EPNHKGJO_03325	1.78e-42	yqkK	-	-	-	-	-	-	-
EPNHKGJO_03326	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EPNHKGJO_03327	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
EPNHKGJO_03328	2.25e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
EPNHKGJO_03329	3.91e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
EPNHKGJO_03330	2.77e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EPNHKGJO_03331	5.66e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EPNHKGJO_03332	3.37e-271	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
EPNHKGJO_03333	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
EPNHKGJO_03334	3.93e-99	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EPNHKGJO_03335	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPNHKGJO_03336	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
EPNHKGJO_03337	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
EPNHKGJO_03338	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
EPNHKGJO_03339	2.86e-244	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
EPNHKGJO_03340	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
EPNHKGJO_03341	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
EPNHKGJO_03342	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
EPNHKGJO_03343	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EPNHKGJO_03344	2.67e-193	ypuA	-	-	S	-	-	-	Secreted protein
EPNHKGJO_03345	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPNHKGJO_03347	5.94e-13	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
EPNHKGJO_03349	2.51e-12	-	-	-	S	-	-	-	SNARE associated Golgi protein
EPNHKGJO_03350	7.41e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
EPNHKGJO_03352	1.54e-121	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
EPNHKGJO_03353	5.98e-72	ypuD	-	-	-	-	-	-	-
EPNHKGJO_03354	2.41e-259	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPNHKGJO_03355	1.24e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
EPNHKGJO_03356	2.1e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EPNHKGJO_03357	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EPNHKGJO_03358	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPNHKGJO_03359	3.29e-116	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
EPNHKGJO_03360	4.45e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EPNHKGJO_03361	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EPNHKGJO_03362	6.13e-128	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
EPNHKGJO_03363	4.11e-273	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
EPNHKGJO_03364	2.17e-134	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
EPNHKGJO_03365	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
EPNHKGJO_03366	1.81e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
EPNHKGJO_03367	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EPNHKGJO_03368	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
EPNHKGJO_03369	1.1e-277	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EPNHKGJO_03370	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_03371	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_03372	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPNHKGJO_03373	6.08e-254	rsiX	-	-	-	-	-	-	-
EPNHKGJO_03374	7.94e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EPNHKGJO_03375	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPNHKGJO_03376	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EPNHKGJO_03377	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
EPNHKGJO_03378	4.66e-257	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
EPNHKGJO_03379	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
EPNHKGJO_03380	4.14e-127	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
EPNHKGJO_03381	2.15e-125	ypbE	-	-	M	-	-	-	Lysin motif
EPNHKGJO_03382	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
EPNHKGJO_03383	4.15e-186	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
EPNHKGJO_03384	3.22e-135	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EPNHKGJO_03385	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
EPNHKGJO_03386	8.76e-223	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
EPNHKGJO_03387	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
EPNHKGJO_03388	1.99e-207	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
EPNHKGJO_03389	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
EPNHKGJO_03390	8.23e-138	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
EPNHKGJO_03391	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
EPNHKGJO_03392	5.8e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
EPNHKGJO_03393	1.06e-259	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
EPNHKGJO_03394	1.33e-234	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EPNHKGJO_03395	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
EPNHKGJO_03396	9.13e-133	yphA	-	-	-	-	-	-	-
EPNHKGJO_03397	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
EPNHKGJO_03398	1.02e-38	ypzH	-	-	-	-	-	-	-
EPNHKGJO_03399	4.77e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
EPNHKGJO_03400	8.18e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
EPNHKGJO_03401	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
EPNHKGJO_03402	1.5e-176	yphF	-	-	-	-	-	-	-
EPNHKGJO_03403	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EPNHKGJO_03404	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EPNHKGJO_03405	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
EPNHKGJO_03406	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EPNHKGJO_03407	7.17e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EPNHKGJO_03408	1.34e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EPNHKGJO_03409	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
EPNHKGJO_03410	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EPNHKGJO_03411	2.13e-182	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
EPNHKGJO_03412	5.88e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EPNHKGJO_03413	1.57e-260	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EPNHKGJO_03414	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EPNHKGJO_03415	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPNHKGJO_03416	6.08e-230	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EPNHKGJO_03417	2.95e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
EPNHKGJO_03418	2.23e-150	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
EPNHKGJO_03419	1.09e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EPNHKGJO_03420	7.71e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EPNHKGJO_03421	1.5e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EPNHKGJO_03422	1.71e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
EPNHKGJO_03423	4.03e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EPNHKGJO_03424	5.27e-299	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
EPNHKGJO_03425	1.83e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
EPNHKGJO_03426	1.86e-98	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
EPNHKGJO_03427	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
EPNHKGJO_03428	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
EPNHKGJO_03429	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
EPNHKGJO_03430	1.2e-127	ypjA	-	-	S	-	-	-	membrane
EPNHKGJO_03431	6.84e-183	ypjB	-	-	S	-	-	-	sporulation protein
EPNHKGJO_03432	2.14e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
EPNHKGJO_03433	5.83e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
EPNHKGJO_03434	1.39e-188	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EPNHKGJO_03435	2.52e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
EPNHKGJO_03436	7.71e-166	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
EPNHKGJO_03437	2.01e-266	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
EPNHKGJO_03438	6.13e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EPNHKGJO_03439	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EPNHKGJO_03440	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EPNHKGJO_03441	1.83e-198	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EPNHKGJO_03442	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EPNHKGJO_03443	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
EPNHKGJO_03444	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
EPNHKGJO_03445	2.27e-103	ypmB	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03446	4.37e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
EPNHKGJO_03447	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
EPNHKGJO_03448	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
EPNHKGJO_03449	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EPNHKGJO_03450	1.43e-121	ypoC	-	-	-	-	-	-	-
EPNHKGJO_03451	1.94e-145	tetR3	-	-	K	ko:K18476	-	ko00000,ko00002,ko03000	Transcriptional regulator
EPNHKGJO_03452	5.17e-149	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	Multidrug transporter MatE
EPNHKGJO_03453	2.08e-87	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	Multidrug transporter MatE
EPNHKGJO_03454	7.28e-207	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
EPNHKGJO_03455	4.96e-155	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EPNHKGJO_03456	3.2e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
EPNHKGJO_03457	1.7e-262	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
EPNHKGJO_03458	7.04e-22	perX	-	-	S	-	-	-	DsrE/DsrF-like family
EPNHKGJO_03459	6.82e-128	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
EPNHKGJO_03460	1.96e-108	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
EPNHKGJO_03461	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03462	3.32e-28	-	-	-	-	-	-	-	-
EPNHKGJO_03463	4.11e-134	yrkC	-	-	G	-	-	-	Cupin domain
EPNHKGJO_03464	1.24e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EPNHKGJO_03465	1.31e-269	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_03466	1.25e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
EPNHKGJO_03467	7.52e-300	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
EPNHKGJO_03468	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
EPNHKGJO_03469	7.28e-218	yrdR	-	-	EG	-	-	-	EamA-like transporter family
EPNHKGJO_03470	2.71e-28	-	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_03471	1.51e-154	-	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_03472	1.67e-251	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
EPNHKGJO_03473	2.09e-213	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
EPNHKGJO_03474	8.34e-86	yodA	-	-	S	-	-	-	tautomerase
EPNHKGJO_03475	2.43e-208	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
EPNHKGJO_03476	2.03e-291	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EPNHKGJO_03477	2.79e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
EPNHKGJO_03478	6.99e-116	azlC	-	-	E	-	-	-	AzlC protein
EPNHKGJO_03479	8.34e-104	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
EPNHKGJO_03480	3.22e-54	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
EPNHKGJO_03481	7.64e-290	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
EPNHKGJO_03483	4.27e-132	yrdC	-	-	Q	-	-	-	Isochorismatase family
EPNHKGJO_03484	2.28e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
EPNHKGJO_03486	1.42e-118	yrdA	-	-	S	-	-	-	DinB family
EPNHKGJO_03487	2.86e-210	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
EPNHKGJO_03488	5.15e-247	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EPNHKGJO_03489	8.38e-189	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
EPNHKGJO_03490	2.29e-160	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
EPNHKGJO_03492	1.04e-166	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
EPNHKGJO_03493	1.39e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPNHKGJO_03494	2.43e-239	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
EPNHKGJO_03495	9.19e-287	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
EPNHKGJO_03496	2.97e-210	yraN	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_03497	1.71e-262	yraM	-	-	S	-	-	-	PrpF protein
EPNHKGJO_03498	4.54e-19	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EPNHKGJO_03499	9.4e-51	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPNHKGJO_03500	2.15e-194	-	-	-	S	-	-	-	Alpha beta hydrolase
EPNHKGJO_03501	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
EPNHKGJO_03502	1.05e-81	-	-	-	T	-	-	-	sh3 domain protein
EPNHKGJO_03503	1.56e-85	-	-	-	E	-	-	-	Glyoxalase-like domain
EPNHKGJO_03504	1.2e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
EPNHKGJO_03505	2.76e-83	yraF	-	-	M	-	-	-	Spore coat protein
EPNHKGJO_03506	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EPNHKGJO_03507	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
EPNHKGJO_03508	2.91e-296	-	-	-	S	-	-	-	DNA replication origin binding
EPNHKGJO_03509	2.81e-07	-	-	-	L	-	-	-	SNF2 family N-terminal domain
EPNHKGJO_03510	1.16e-157	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
EPNHKGJO_03511	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
EPNHKGJO_03512	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_03513	1.7e-282	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EPNHKGJO_03514	1.05e-22	-	-	-	-	-	-	-	-
EPNHKGJO_03515	2.86e-215	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
EPNHKGJO_03516	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
EPNHKGJO_03517	7.3e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_03518	4.8e-114	ykuD	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03519	9.98e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
EPNHKGJO_03520	1.06e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_03521	0.0	ybfG	-	-	M	-	-	-	Putative peptidoglycan binding domain
EPNHKGJO_03523	2.91e-297	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
EPNHKGJO_03525	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03526	2.62e-121	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
EPNHKGJO_03527	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
EPNHKGJO_03528	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
EPNHKGJO_03529	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_03530	3.53e-110	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
EPNHKGJO_03531	1.01e-221	ykuO	-	-	-	-	-	-	-
EPNHKGJO_03532	1.03e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
EPNHKGJO_03533	3.74e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EPNHKGJO_03534	4.43e-273	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EPNHKGJO_03535	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
EPNHKGJO_03536	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
EPNHKGJO_03537	2.8e-129	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
EPNHKGJO_03538	6.01e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
EPNHKGJO_03539	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
EPNHKGJO_03540	0.0	ybeC	-	-	E	-	-	-	amino acid
EPNHKGJO_03541	4.27e-66	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
EPNHKGJO_03542	2.44e-65	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
EPNHKGJO_03543	7.83e-96	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
EPNHKGJO_03544	5.68e-30	-	-	-	K	-	-	-	Helix-turn-helix
EPNHKGJO_03546	8.91e-168	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
EPNHKGJO_03547	1.8e-83	-	-	-	-	-	-	-	-
EPNHKGJO_03551	3e-45	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
EPNHKGJO_03552	1.07e-194	-	3.5.1.28	-	MT	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
EPNHKGJO_03553	1.12e-39	-	-	-	S	-	-	-	BhlA holin family
EPNHKGJO_03554	3.46e-05	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
EPNHKGJO_03556	2.49e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
EPNHKGJO_03557	0.0	-	-	-	S	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
EPNHKGJO_03558	3.43e-86	-	-	-	L	-	-	-	Prophage endopeptidase tail
EPNHKGJO_03559	1.37e-67	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
EPNHKGJO_03560	1.68e-135	-	-	-	D	-	-	-	phage tail tape measure protein
EPNHKGJO_03562	3.67e-33	-	-	-	-	-	-	-	-
EPNHKGJO_03563	7.76e-66	-	-	-	N	-	-	-	domain, Protein
EPNHKGJO_03565	3.74e-20	-	-	-	-	-	-	-	-
EPNHKGJO_03566	1.99e-34	-	-	-	-	-	-	-	-
EPNHKGJO_03568	3.49e-102	-	-	-	-	-	-	-	-
EPNHKGJO_03569	1.19e-07	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
EPNHKGJO_03570	2.83e-105	-	-	-	S	-	-	-	Phage minor capsid protein 2
EPNHKGJO_03571	3.63e-192	-	-	-	-	-	-	-	-
EPNHKGJO_03572	1.4e-28	-	-	-	S	-	-	-	Helix-turn-helix of insertion element transposase
EPNHKGJO_03573	7.57e-169	-	-	-	S	-	-	-	TIGRFAM Phage uncharacterised protein, C-terminal
EPNHKGJO_03574	5.29e-85	-	-	-	L	-	-	-	Phage integrase family
EPNHKGJO_03575	8.53e-09	-	-	-	-	-	-	-	-
EPNHKGJO_03577	2.1e-52	-	-	-	-	-	-	-	-
EPNHKGJO_03585	6.79e-38	-	-	-	-	-	-	-	-
EPNHKGJO_03586	5.74e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
EPNHKGJO_03588	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
EPNHKGJO_03589	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
EPNHKGJO_03590	4.05e-267	yfhI	-	-	EGP	-	-	-	-transporter
EPNHKGJO_03592	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
EPNHKGJO_03593	2.67e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
EPNHKGJO_03594	2.56e-218	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
EPNHKGJO_03596	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
EPNHKGJO_03597	2.87e-138	yfhC	-	-	C	-	-	-	nitroreductase
EPNHKGJO_03598	4.05e-210	yfhB	-	-	S	-	-	-	PhzF family
EPNHKGJO_03599	3.49e-227	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_03600	1.04e-223	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_03601	9.03e-230	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
EPNHKGJO_03602	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EPNHKGJO_03603	2.11e-103	yfiV	-	-	K	-	-	-	transcriptional
EPNHKGJO_03604	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
EPNHKGJO_03605	2.31e-127	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
EPNHKGJO_03606	4.25e-249	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EPNHKGJO_03607	4.55e-127	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EPNHKGJO_03608	1.89e-128	padR	-	-	K	-	-	-	transcriptional
EPNHKGJO_03609	2.13e-66	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
EPNHKGJO_03610	1.7e-262	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
EPNHKGJO_03611	6.49e-268	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
EPNHKGJO_03612	6.48e-216	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_03613	6.07e-146	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
EPNHKGJO_03614	2.94e-273	baeS	-	-	T	-	-	-	Histidine kinase
EPNHKGJO_03616	6.76e-291	-	-	-	S	-	-	-	Oxidoreductase
EPNHKGJO_03617	2.23e-233	-	-	-	G	-	-	-	Xylose isomerase
EPNHKGJO_03618	0.0	yfiG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPNHKGJO_03619	5.61e-223	-	-	-	K	ko:K02099	-	ko00000,ko03000	AraC-like ligand binding domain
EPNHKGJO_03620	2.97e-208	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
EPNHKGJO_03621	3.34e-83	yfiD3	-	-	S	-	-	-	DoxX
EPNHKGJO_03622	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
EPNHKGJO_03623	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
EPNHKGJO_03624	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_03625	3.54e-180	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
EPNHKGJO_03626	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EPNHKGJO_03627	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
EPNHKGJO_03628	1.46e-267	yfjB	-	-	-	-	-	-	-
EPNHKGJO_03629	2.06e-184	yfjC	-	-	-	-	-	-	-
EPNHKGJO_03630	6.08e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
EPNHKGJO_03631	1.5e-74	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
EPNHKGJO_03632	8.16e-36	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
EPNHKGJO_03633	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
EPNHKGJO_03634	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EPNHKGJO_03635	5.21e-259	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPNHKGJO_03636	9.2e-243	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EPNHKGJO_03637	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EPNHKGJO_03639	7.85e-110	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
EPNHKGJO_03640	5.07e-236	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPNHKGJO_03641	4.32e-59	-	-	-	S	-	-	-	YfzA-like protein
EPNHKGJO_03642	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPNHKGJO_03643	2.76e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EPNHKGJO_03644	6.15e-234	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
EPNHKGJO_03645	3.25e-192	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EPNHKGJO_03646	1.4e-195	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
EPNHKGJO_03647	3.26e-36	yfjT	-	-	-	-	-	-	-
EPNHKGJO_03648	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
EPNHKGJO_03649	1.81e-190	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
EPNHKGJO_03650	1.06e-188	yfkD	-	-	S	-	-	-	YfkD-like protein
EPNHKGJO_03651	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
EPNHKGJO_03652	4.48e-277	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_03653	2.74e-11	-	-	-	-	-	-	-	-
EPNHKGJO_03654	1.37e-183	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
EPNHKGJO_03655	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
EPNHKGJO_03656	1.39e-102	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPNHKGJO_03657	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
EPNHKGJO_03658	1.03e-264	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_03659	6.14e-111	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
EPNHKGJO_03660	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
EPNHKGJO_03661	2.93e-158	frp	-	-	C	-	-	-	nitroreductase
EPNHKGJO_03662	3.55e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
EPNHKGJO_03663	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
EPNHKGJO_03664	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_03665	1.95e-142	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
EPNHKGJO_03666	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
EPNHKGJO_03667	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
EPNHKGJO_03668	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EPNHKGJO_03669	7.72e-177	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
EPNHKGJO_03670	2.1e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
EPNHKGJO_03671	6.9e-27	yflI	-	-	-	-	-	-	-
EPNHKGJO_03672	6.9e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03673	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
EPNHKGJO_03674	9.67e-276	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EPNHKGJO_03675	1.63e-190	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
EPNHKGJO_03676	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
EPNHKGJO_03677	5.66e-230	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
EPNHKGJO_03678	1.33e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
EPNHKGJO_03679	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
EPNHKGJO_03680	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
EPNHKGJO_03681	2.01e-306	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
EPNHKGJO_03682	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
EPNHKGJO_03683	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
EPNHKGJO_03684	1.53e-216	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EPNHKGJO_03685	8.17e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_03686	2.1e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPNHKGJO_03687	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
EPNHKGJO_03688	6.98e-241	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
EPNHKGJO_03689	2.55e-105	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
EPNHKGJO_03690	8.46e-263	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
EPNHKGJO_03691	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EPNHKGJO_03692	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
EPNHKGJO_03693	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
EPNHKGJO_03694	7.58e-98	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
EPNHKGJO_03695	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EPNHKGJO_03696	9.89e-159	yfmS	-	-	NT	-	-	-	chemotaxis protein
EPNHKGJO_03697	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPNHKGJO_03698	1.39e-311	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
EPNHKGJO_03699	9.84e-115	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
EPNHKGJO_03700	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_03701	3.19e-241	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
EPNHKGJO_03702	6.42e-282	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
EPNHKGJO_03703	1.1e-228	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
EPNHKGJO_03704	4.79e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
EPNHKGJO_03705	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
EPNHKGJO_03706	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
EPNHKGJO_03707	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
EPNHKGJO_03708	2.38e-250	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
EPNHKGJO_03709	1.27e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
EPNHKGJO_03710	2.81e-180	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
EPNHKGJO_03711	0.000141	-	-	-	-	-	-	-	-
EPNHKGJO_03712	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
EPNHKGJO_03713	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_03714	1.46e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
EPNHKGJO_03715	4.79e-78	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
EPNHKGJO_03716	1.67e-219	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EPNHKGJO_03717	6.82e-78	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
EPNHKGJO_03718	3.18e-193	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
EPNHKGJO_03719	4.48e-35	ykzI	-	-	-	-	-	-	-
EPNHKGJO_03720	5.28e-152	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
EPNHKGJO_03721	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
EPNHKGJO_03722	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
EPNHKGJO_03724	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
EPNHKGJO_03725	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EPNHKGJO_03726	9.88e-300	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPNHKGJO_03727	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EPNHKGJO_03728	1.51e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EPNHKGJO_03729	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
EPNHKGJO_03730	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
EPNHKGJO_03731	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPNHKGJO_03732	5.59e-185	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
EPNHKGJO_03733	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
EPNHKGJO_03734	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPNHKGJO_03735	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EPNHKGJO_03736	1.01e-147	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
EPNHKGJO_03737	1.15e-196	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
EPNHKGJO_03738	3.77e-306	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
EPNHKGJO_03739	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
EPNHKGJO_03740	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
EPNHKGJO_03741	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
EPNHKGJO_03742	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
EPNHKGJO_03743	3.9e-213	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPNHKGJO_03744	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EPNHKGJO_03745	7.71e-52	ykoA	-	-	-	-	-	-	-
EPNHKGJO_03746	1.42e-133	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
EPNHKGJO_03747	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EPNHKGJO_03748	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
EPNHKGJO_03749	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_03750	3.88e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
EPNHKGJO_03751	1.23e-159	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_03752	2.72e-232	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPNHKGJO_03753	1.6e-151	yknW	-	-	S	-	-	-	Yip1 domain
EPNHKGJO_03754	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
EPNHKGJO_03755	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
EPNHKGJO_03756	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EPNHKGJO_03757	3.83e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
EPNHKGJO_03758	1.64e-120	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
EPNHKGJO_03759	1.23e-312	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
EPNHKGJO_03760	8.86e-244	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EPNHKGJO_03761	1.86e-141	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EPNHKGJO_03762	5.72e-199	yknT	-	-	-	ko:K06437	-	ko00000	-
EPNHKGJO_03763	7.57e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
EPNHKGJO_03764	5.57e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
EPNHKGJO_03765	1.01e-312	-	-	-	I	-	-	-	Pfam Lipase (class 3)
EPNHKGJO_03766	4.47e-56	-	-	-	-	-	-	-	-
EPNHKGJO_03767	1.04e-113	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPNHKGJO_03768	5.49e-47	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EPNHKGJO_03769	2.2e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
EPNHKGJO_03770	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03771	2.6e-39	-	-	-	-	-	-	-	-
EPNHKGJO_03772	1.83e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
EPNHKGJO_03773	1.12e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPNHKGJO_03774	1.12e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
EPNHKGJO_03775	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
EPNHKGJO_03776	3.99e-09	-	-	-	-	-	-	-	-
EPNHKGJO_03777	9.15e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
EPNHKGJO_03778	2.69e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_03780	2.79e-167	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
EPNHKGJO_03781	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_03782	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
EPNHKGJO_03783	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPNHKGJO_03784	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_03785	5.86e-255	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
EPNHKGJO_03786	1.07e-162	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPNHKGJO_03787	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
EPNHKGJO_03788	8.11e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EPNHKGJO_03789	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
EPNHKGJO_03790	2.56e-220	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EPNHKGJO_03791	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPNHKGJO_03792	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPNHKGJO_03793	4.32e-298	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPNHKGJO_03794	1.77e-32	yqzJ	-	-	-	-	-	-	-
EPNHKGJO_03795	1.03e-178	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPNHKGJO_03796	1.57e-177	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
EPNHKGJO_03797	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
EPNHKGJO_03798	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EPNHKGJO_03799	6.4e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EPNHKGJO_03800	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPNHKGJO_03801	2.73e-152	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EPNHKGJO_03802	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EPNHKGJO_03803	1.44e-290	ybbR	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_03804	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPNHKGJO_03805	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EPNHKGJO_03806	1.22e-216	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EPNHKGJO_03807	3.59e-152	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
EPNHKGJO_03808	5.25e-127	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPNHKGJO_03809	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EPNHKGJO_03810	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
EPNHKGJO_03811	1.63e-121	ybcF	-	-	P	-	-	-	carbonic anhydrase
EPNHKGJO_03813	1.6e-63	-	-	-	-	-	-	-	-
EPNHKGJO_03814	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
EPNHKGJO_03815	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
EPNHKGJO_03816	6.59e-258	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
EPNHKGJO_03818	7.24e-304	-	-	-	J	-	-	-	4Fe-4S single cluster domain
EPNHKGJO_03819	0.0	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
EPNHKGJO_03820	2.22e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EPNHKGJO_03821	1e-310	skfF	-	-	S	-	-	-	ABC transporter
EPNHKGJO_03822	3.88e-118	-	-	-	C	-	-	-	HEAT repeats
EPNHKGJO_03823	5.88e-103	-	-	-	CO	-	-	-	Thioredoxin-like domain
EPNHKGJO_03824	8.65e-228	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EPNHKGJO_03825	6.9e-158	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
EPNHKGJO_03826	4.22e-214	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
EPNHKGJO_03828	1.68e-179	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
EPNHKGJO_03829	3.67e-193	ybdN	-	-	-	-	-	-	-
EPNHKGJO_03830	7.06e-271	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
EPNHKGJO_03831	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
EPNHKGJO_03832	2.23e-50	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
EPNHKGJO_03833	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
EPNHKGJO_03834	1.24e-191	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
EPNHKGJO_03835	4.25e-215	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
EPNHKGJO_03836	3.64e-40	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
EPNHKGJO_03837	1.11e-54	ybyB	-	-	-	-	-	-	-
EPNHKGJO_03838	0.0	ybeC	-	-	E	-	-	-	amino acid
EPNHKGJO_03839	9.95e-211	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
EPNHKGJO_03840	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
EPNHKGJO_03841	1.7e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
EPNHKGJO_03842	2.35e-215	ybfA	-	-	K	-	-	-	FR47-like protein
EPNHKGJO_03843	7.54e-284	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_03845	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
EPNHKGJO_03846	8.11e-86	ybfH	-	-	EG	-	-	-	EamA-like transporter family
EPNHKGJO_03847	1.88e-61	ybfH	-	-	EG	-	-	-	EamA-like transporter family
EPNHKGJO_03848	1.74e-186	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
EPNHKGJO_03849	1.54e-269	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EPNHKGJO_03850	8.01e-227	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
EPNHKGJO_03852	1.2e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase family
EPNHKGJO_03853	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPNHKGJO_03854	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
EPNHKGJO_03855	2.5e-189	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EPNHKGJO_03856	3.88e-60	ybfN	-	-	-	-	-	-	-
EPNHKGJO_03857	9.32e-316	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
EPNHKGJO_03858	2.35e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
EPNHKGJO_03859	1.73e-272	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPNHKGJO_03860	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EPNHKGJO_03861	2.48e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EPNHKGJO_03862	5.79e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
EPNHKGJO_03864	1.52e-259	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
EPNHKGJO_03865	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
EPNHKGJO_03866	6.14e-232	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
EPNHKGJO_03868	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
EPNHKGJO_03869	4.35e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
EPNHKGJO_03870	3.4e-292	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_03871	3.33e-215	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
EPNHKGJO_03872	7.94e-220	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
EPNHKGJO_03873	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPNHKGJO_03874	5.05e-60	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_03875	9.33e-200	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
EPNHKGJO_03876	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
EPNHKGJO_03877	7.68e-160	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
EPNHKGJO_03878	1.58e-84	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
EPNHKGJO_03879	8.78e-96	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
EPNHKGJO_03880	4.69e-122	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
EPNHKGJO_03881	1.92e-67	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
EPNHKGJO_03882	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
EPNHKGJO_03883	2.44e-216	eamA1	-	-	EG	-	-	-	spore germination
EPNHKGJO_03884	9.12e-161	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_03885	3.69e-99	ycbM	-	-	T	-	-	-	Histidine kinase
EPNHKGJO_03886	1.25e-98	ycbM	-	-	T	-	-	-	Histidine kinase
EPNHKGJO_03887	9.59e-216	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_03888	4.75e-147	-	-	-	S	-	-	-	ABC-2 family transporter protein
EPNHKGJO_03889	2.48e-73	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
EPNHKGJO_03890	2.05e-99	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
EPNHKGJO_03891	3.38e-06	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma factor
EPNHKGJO_03892	6.43e-65	XK27_07210	-	-	S	-	-	-	B3/4 domain
EPNHKGJO_03894	5.42e-11	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPNHKGJO_03895	6.95e-51	-	-	-	S	ko:K07006	-	ko00000	flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase
EPNHKGJO_03896	1.56e-42	-	-	-	S	-	-	-	CGNR zinc finger
EPNHKGJO_03897	1.07e-123	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartate-semialdehyde dehydrogenase family
EPNHKGJO_03898	1.78e-152	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
EPNHKGJO_03899	3.41e-102	-	-	-	I	-	-	-	Fatty acid desaturase
EPNHKGJO_03900	6.05e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF444)
EPNHKGJO_03901	1.64e-56	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate synthase activity
EPNHKGJO_03902	8.48e-153	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
EPNHKGJO_03903	2.93e-91	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
EPNHKGJO_03904	9.39e-246	-	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPNHKGJO_03905	1.75e-83	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
EPNHKGJO_03906	1.5e-55	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
EPNHKGJO_03907	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
EPNHKGJO_03908	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EPNHKGJO_03909	1.26e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPNHKGJO_03910	2.94e-155	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EPNHKGJO_03911	1.98e-258	ycbU	-	-	E	-	-	-	Selenocysteine lyase
EPNHKGJO_03912	2.39e-300	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
EPNHKGJO_03913	7.64e-131	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
EPNHKGJO_03914	2.3e-255	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EPNHKGJO_03915	4.67e-146	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EPNHKGJO_03916	6.61e-73	-	-	-	S	-	-	-	RDD family
EPNHKGJO_03917	5.86e-254	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
EPNHKGJO_03918	1.85e-214	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
EPNHKGJO_03919	3.81e-160	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
EPNHKGJO_03920	2.2e-170	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
EPNHKGJO_03921	1.09e-254	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
EPNHKGJO_03922	1.51e-77	yccK	-	-	C	-	-	-	Aldo keto reductase
EPNHKGJO_03923	4.23e-114	yccK	-	-	C	-	-	-	Aldo keto reductase
EPNHKGJO_03924	6.42e-240	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
EPNHKGJO_03925	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPNHKGJO_03926	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPNHKGJO_03927	2.65e-123	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
EPNHKGJO_03928	5.52e-246	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
EPNHKGJO_03929	9.73e-180	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
EPNHKGJO_03930	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
EPNHKGJO_03931	1.31e-219	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
EPNHKGJO_03932	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EPNHKGJO_03933	1.88e-172	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EPNHKGJO_03934	9.86e-237	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPNHKGJO_03935	1.78e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
EPNHKGJO_03936	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
EPNHKGJO_03937	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
EPNHKGJO_03938	4.1e-176	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
EPNHKGJO_03939	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
EPNHKGJO_03940	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
EPNHKGJO_03942	4.93e-293	-	-	-	I	-	-	-	Pfam Lipase (class 3)
EPNHKGJO_03943	1.09e-62	-	-	-	-	-	-	-	-
EPNHKGJO_03944	2.81e-41	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
EPNHKGJO_03945	1.91e-43	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
EPNHKGJO_03946	1.21e-128	-	-	-	L	-	-	-	Phage integrase family
EPNHKGJO_03947	5.62e-140	-	-	-	S	-	-	-	Helix-turn-helix domain
EPNHKGJO_03948	8.57e-40	-	-	-	L	-	-	-	Phage integrase family
EPNHKGJO_03950	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EPNHKGJO_03951	7.59e-147	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
EPNHKGJO_03952	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
EPNHKGJO_03953	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
EPNHKGJO_03954	5.63e-197	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
EPNHKGJO_03955	6.56e-188	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
EPNHKGJO_03956	1.63e-235	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
EPNHKGJO_03958	1.96e-220	-	-	-	L	-	-	-	TIGRFAM Transposase, IS605 OrfB, C-terminal
EPNHKGJO_03960	8.64e-17	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_03961	1.67e-225	-	-	-	-	-	-	-	-
EPNHKGJO_03962	0.0	-	-	-	S	-	-	-	DNA-sulfur modification-associated
EPNHKGJO_03963	2.39e-253	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPNHKGJO_03968	1.87e-86	-	-	-	-	-	-	-	-
EPNHKGJO_03969	3.17e-102	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
EPNHKGJO_03970	7.24e-205	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
EPNHKGJO_03971	8.57e-222	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_03972	6.22e-103	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPNHKGJO_03973	1.02e-194	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPNHKGJO_03974	1.25e-263	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
EPNHKGJO_03975	2.86e-246	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
EPNHKGJO_03976	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
EPNHKGJO_03977	1.3e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
EPNHKGJO_03978	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPNHKGJO_03979	0.0	-	-	-	-	-	-	-	-
EPNHKGJO_03980	3.8e-273	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EPNHKGJO_03981	1.9e-185	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EPNHKGJO_03982	3.82e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
EPNHKGJO_03983	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferase 1 domain A
EPNHKGJO_03984	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EPNHKGJO_03985	2.06e-194	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
EPNHKGJO_03986	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EPNHKGJO_03987	2.13e-127	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
EPNHKGJO_03988	5.43e-05	-	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase-like
EPNHKGJO_03989	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
EPNHKGJO_03990	0.0	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EPNHKGJO_03992	7.57e-43	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
EPNHKGJO_03993	1.24e-97	-	-	-	S	-	-	-	MTH538 TIR-like domain (DUF1863)
EPNHKGJO_03994	2.48e-233	-	-	-	K	-	-	-	SIR2-like domain
EPNHKGJO_03996	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
EPNHKGJO_03997	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
EPNHKGJO_03998	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
EPNHKGJO_03999	8.37e-161	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
EPNHKGJO_04000	1.23e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
EPNHKGJO_04001	3.13e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
EPNHKGJO_04003	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
EPNHKGJO_04004	2.07e-97	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
EPNHKGJO_04005	1.32e-156	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
EPNHKGJO_04006	3.23e-149	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
EPNHKGJO_04007	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
EPNHKGJO_04008	3.85e-282	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
EPNHKGJO_04009	2.16e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
EPNHKGJO_04010	7.18e-278	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
EPNHKGJO_04011	2.08e-263	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
EPNHKGJO_04012	1.66e-246	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
EPNHKGJO_04013	1.06e-256	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
EPNHKGJO_04014	3.75e-243	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
EPNHKGJO_04015	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPNHKGJO_04016	9.14e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EPNHKGJO_04017	2.88e-77	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
EPNHKGJO_04018	9.08e-280	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
EPNHKGJO_04019	1.46e-238	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
EPNHKGJO_04020	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
EPNHKGJO_04021	1.48e-307	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EPNHKGJO_04022	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
EPNHKGJO_04023	6.85e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
EPNHKGJO_04024	6.42e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_04025	1.32e-291	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
EPNHKGJO_04026	2.15e-300	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
EPNHKGJO_04027	1.1e-193	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
EPNHKGJO_04028	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
EPNHKGJO_04029	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
EPNHKGJO_04030	3.48e-255	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
EPNHKGJO_04031	5.96e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
EPNHKGJO_04032	1.63e-206	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
EPNHKGJO_04033	2.9e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
EPNHKGJO_04034	3.25e-253	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_04035	7.53e-137	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPNHKGJO_04036	4.23e-42	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
EPNHKGJO_04037	2.39e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
EPNHKGJO_04038	2.6e-174	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EPNHKGJO_04039	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EPNHKGJO_04040	1.14e-169	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EPNHKGJO_04041	1.44e-41	-	-	-	S	-	-	-	Glycosyl hydrolase
EPNHKGJO_04042	1.15e-167	-	-	-	S	-	-	-	Glycosyl hydrolase
EPNHKGJO_04043	2.36e-305	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
EPNHKGJO_04044	5.59e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
EPNHKGJO_04045	2.83e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_04046	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPNHKGJO_04047	4.14e-256	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
EPNHKGJO_04048	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPNHKGJO_04049	2.42e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EPNHKGJO_04050	9.48e-237	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPNHKGJO_04051	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
EPNHKGJO_04052	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPNHKGJO_04053	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
EPNHKGJO_04054	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EPNHKGJO_04055	6.83e-97	yvbK	-	-	K	-	-	-	acetyltransferase
EPNHKGJO_04056	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
EPNHKGJO_04057	3.11e-154	yvbI	-	-	M	-	-	-	Membrane
EPNHKGJO_04058	2.96e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
EPNHKGJO_04059	1.32e-133	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
EPNHKGJO_04060	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
EPNHKGJO_04061	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EPNHKGJO_04062	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
EPNHKGJO_04063	5e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EPNHKGJO_04064	1.03e-146	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
EPNHKGJO_04065	9.63e-60	sdpR	-	-	K	-	-	-	transcriptional
EPNHKGJO_04066	8.32e-133	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
EPNHKGJO_04068	1.13e-222	-	-	-	-	-	-	-	-
EPNHKGJO_04069	2.75e-11	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
EPNHKGJO_04070	1.9e-121	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
EPNHKGJO_04071	9.58e-267	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EPNHKGJO_04072	2.57e-141	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
EPNHKGJO_04073	2.37e-220	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EPNHKGJO_04074	1.07e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
EPNHKGJO_04075	5.82e-258	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
EPNHKGJO_04076	3.65e-24	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
EPNHKGJO_04077	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
EPNHKGJO_04078	1.98e-91	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
EPNHKGJO_04079	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
EPNHKGJO_04080	4.9e-48	yvzC	-	-	K	-	-	-	transcriptional
EPNHKGJO_04081	3.87e-194	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
EPNHKGJO_04082	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
EPNHKGJO_04083	2.42e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
EPNHKGJO_04084	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EPNHKGJO_04085	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EPNHKGJO_04087	7.66e-180	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNHKGJO_04088	5.77e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EPNHKGJO_04089	2.04e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
EPNHKGJO_04090	8.22e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
EPNHKGJO_04091	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
EPNHKGJO_04092	2.08e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EPNHKGJO_04093	1.4e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
EPNHKGJO_04094	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
EPNHKGJO_04095	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
EPNHKGJO_04096	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
EPNHKGJO_04097	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
EPNHKGJO_04098	1.71e-137	bdbD	-	-	O	-	-	-	Thioredoxin
EPNHKGJO_04099	1.64e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
EPNHKGJO_04102	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
EPNHKGJO_04103	1.19e-23	-	-	-	-	-	-	-	-
EPNHKGJO_04104	2.12e-163	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_04105	7.55e-44	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPNHKGJO_04106	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EPNHKGJO_04107	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
EPNHKGJO_04108	2.68e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
EPNHKGJO_04109	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPNHKGJO_04110	2.91e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
EPNHKGJO_04111	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
EPNHKGJO_04112	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
EPNHKGJO_04113	6.69e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
EPNHKGJO_04114	2.39e-235	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
EPNHKGJO_04116	2.45e-14	-	-	-	-	-	-	-	-
EPNHKGJO_04117	2.24e-23	-	-	-	-	-	-	-	-
EPNHKGJO_04119	2.08e-119	-	-	-	A	-	-	-	Belongs to the 'phage' integrase family
EPNHKGJO_04120	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EPNHKGJO_04121	5.91e-178	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EPNHKGJO_04122	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
EPNHKGJO_04123	2.61e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EPNHKGJO_04124	3.91e-226	ykvI	-	-	S	-	-	-	membrane
EPNHKGJO_04125	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
EPNHKGJO_04126	9.19e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
EPNHKGJO_04127	1.06e-166	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
EPNHKGJO_04128	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
EPNHKGJO_04129	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
EPNHKGJO_04130	1.88e-91	eag	-	-	-	-	-	-	-
EPNHKGJO_04132	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
EPNHKGJO_04133	8.7e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EPNHKGJO_04134	2.15e-145	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EPNHKGJO_04135	6.91e-173	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EPNHKGJO_04136	3.25e-293	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EPNHKGJO_04137	6.56e-294	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EPNHKGJO_04138	8.12e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EPNHKGJO_04139	5.81e-292	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EPNHKGJO_04140	5.4e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EPNHKGJO_04142	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPNHKGJO_04143	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_04144	3.2e-242	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
EPNHKGJO_04145	1.77e-28	ykzE	-	-	-	-	-	-	-
EPNHKGJO_04147	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
EPNHKGJO_04148	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
EPNHKGJO_04149	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
EPNHKGJO_04150	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
EPNHKGJO_04151	1.41e-199	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
EPNHKGJO_04152	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPNHKGJO_04153	4.63e-227	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EPNHKGJO_04154	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
EPNHKGJO_04155	2.43e-76	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
EPNHKGJO_04156	2.46e-74	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
EPNHKGJO_04157	3.75e-131	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
EPNHKGJO_04158	1.89e-31	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
EPNHKGJO_04159	1.41e-69	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
EPNHKGJO_04160	7.24e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EPNHKGJO_04161	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
EPNHKGJO_04162	2.23e-236	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
EPNHKGJO_04163	0.0	ykoS	-	-	-	-	-	-	-
EPNHKGJO_04164	7.22e-197	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
EPNHKGJO_04165	2.07e-126	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
EPNHKGJO_04166	1.76e-277	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
EPNHKGJO_04167	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
EPNHKGJO_04168	3.04e-36	ykoL	-	-	-	-	-	-	-
EPNHKGJO_04169	1.63e-25	-	-	-	-	-	-	-	-
EPNHKGJO_04170	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
EPNHKGJO_04171	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
EPNHKGJO_04173	1.45e-08	-	-	-	-	-	-	-	-
EPNHKGJO_04174	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
EPNHKGJO_04175	3.74e-143	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
EPNHKGJO_04176	1.42e-305	ykoH	-	-	T	-	-	-	Histidine kinase
EPNHKGJO_04177	4.3e-159	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_04178	2.01e-141	ykoF	-	-	S	-	-	-	YKOF-related Family
EPNHKGJO_04179	2.81e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
EPNHKGJO_04180	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPNHKGJO_04181	3.65e-173	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
EPNHKGJO_04182	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPNHKGJO_04183	4.27e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
EPNHKGJO_04184	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EPNHKGJO_04188	3.8e-88	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EPNHKGJO_04190	4.02e-82	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
EPNHKGJO_04191	5.44e-278	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
EPNHKGJO_04192	1.15e-237	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
EPNHKGJO_04193	2.18e-83	cgeA	-	-	-	ko:K06319	-	ko00000	-
EPNHKGJO_04194	1.76e-58	cgeC	-	-	-	ko:K06321	-	ko00000	-
EPNHKGJO_04195	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
EPNHKGJO_04196	3.98e-184	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
EPNHKGJO_04197	4.15e-303	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPNHKGJO_04199	6.38e-151	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EPNHKGJO_04200	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
EPNHKGJO_04201	1.24e-195	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
EPNHKGJO_04202	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
EPNHKGJO_04203	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
EPNHKGJO_04204	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
EPNHKGJO_04205	7.44e-159	yodN	-	-	-	-	-	-	-
EPNHKGJO_04207	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
EPNHKGJO_04208	2.23e-135	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
EPNHKGJO_04209	3.35e-71	yodL	-	-	S	-	-	-	YodL-like
EPNHKGJO_04210	2.08e-12	-	-	-	-	-	-	-	-
EPNHKGJO_04211	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
EPNHKGJO_04212	7.71e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
EPNHKGJO_04213	4.86e-41	yodI	-	-	-	-	-	-	-
EPNHKGJO_04214	3.03e-166	yodH	-	-	Q	-	-	-	Methyltransferase
EPNHKGJO_04215	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
EPNHKGJO_04216	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPNHKGJO_04217	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
EPNHKGJO_04218	1.18e-223	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
EPNHKGJO_04219	3.61e-144	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
EPNHKGJO_04220	8.07e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EPNHKGJO_04221	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
EPNHKGJO_04222	7.84e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EPNHKGJO_04223	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPNHKGJO_04224	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
EPNHKGJO_04225	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_04226	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
EPNHKGJO_04227	9.27e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
EPNHKGJO_04228	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
EPNHKGJO_04229	9.38e-95	ytwI	-	-	S	-	-	-	membrane
EPNHKGJO_04230	7.83e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
EPNHKGJO_04231	3.85e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
EPNHKGJO_04232	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
EPNHKGJO_04233	1.89e-228	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EPNHKGJO_04234	4e-233	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EPNHKGJO_04235	1.25e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EPNHKGJO_04236	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
EPNHKGJO_04237	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
EPNHKGJO_04238	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
EPNHKGJO_04239	5.12e-112	ytrI	-	-	-	-	-	-	-
EPNHKGJO_04240	1.15e-39	-	-	-	-	-	-	-	-
EPNHKGJO_04241	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
EPNHKGJO_04242	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
EPNHKGJO_04243	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
EPNHKGJO_04244	8.36e-202	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EPNHKGJO_04245	5.44e-235	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
EPNHKGJO_04246	1.98e-165	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
EPNHKGJO_04247	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPNHKGJO_04248	5.26e-63	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
EPNHKGJO_04249	8.4e-235	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPNHKGJO_04250	6.61e-183	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
EPNHKGJO_04251	4.76e-155	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPNHKGJO_04252	1.66e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPNHKGJO_04253	1.34e-192	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
EPNHKGJO_04254	9.11e-195	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
EPNHKGJO_04255	4e-128	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
EPNHKGJO_04256	4.99e-223	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
EPNHKGJO_04257	5.47e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
EPNHKGJO_04258	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_04260	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
EPNHKGJO_04261	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
EPNHKGJO_04262	9.5e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
EPNHKGJO_04263	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPNHKGJO_04264	2.44e-220	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
EPNHKGJO_04265	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EPNHKGJO_04266	5.02e-90	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
EPNHKGJO_04267	6.29e-144	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
EPNHKGJO_04268	8.23e-112	yteJ	-	-	S	-	-	-	RDD family
EPNHKGJO_04269	3.96e-229	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
EPNHKGJO_04270	1.69e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPNHKGJO_04271	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
EPNHKGJO_04272	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EPNHKGJO_04273	7.14e-39	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
EPNHKGJO_04274	2.55e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPNHKGJO_04275	4.75e-267	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
EPNHKGJO_04276	8.23e-305	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EPNHKGJO_04277	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EPNHKGJO_04278	3.58e-196	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EPNHKGJO_04279	2.82e-140	yttP	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_04280	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
EPNHKGJO_04281	0.0	-	-	-	-	-	-	-	-
EPNHKGJO_04282	7.15e-122	-	-	-	-	-	-	-	-
EPNHKGJO_04283	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
EPNHKGJO_04284	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EPNHKGJO_04285	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
EPNHKGJO_04286	4.48e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EPNHKGJO_04287	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
EPNHKGJO_04288	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_04289	1.3e-241	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
EPNHKGJO_04290	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
EPNHKGJO_04291	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
EPNHKGJO_04292	2.74e-287	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
EPNHKGJO_04293	7.5e-92	-	-	-	K	-	-	-	helix_turn_helix ASNC type
EPNHKGJO_04294	2.32e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
EPNHKGJO_04295	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
EPNHKGJO_04296	8.88e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EPNHKGJO_04297	1.15e-238	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
EPNHKGJO_04298	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EPNHKGJO_04299	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPNHKGJO_04300	1.91e-166	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPNHKGJO_04301	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPNHKGJO_04302	2.78e-166	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
EPNHKGJO_04303	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EPNHKGJO_04304	4.28e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPNHKGJO_04305	9.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EPNHKGJO_04306	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
EPNHKGJO_04307	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
EPNHKGJO_04309	1.95e-163	yebC	-	-	M	-	-	-	Membrane
EPNHKGJO_04310	4.65e-281	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
EPNHKGJO_04311	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
EPNHKGJO_04312	7.14e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPNHKGJO_04313	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
EPNHKGJO_04314	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
EPNHKGJO_04315	3.58e-282	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EPNHKGJO_04316	1.88e-224	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
EPNHKGJO_04317	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPNHKGJO_04318	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
EPNHKGJO_04319	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
EPNHKGJO_04320	1.88e-226	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
EPNHKGJO_04321	4.9e-200	-	-	-	I	-	-	-	Alpha/beta hydrolase family
EPNHKGJO_04322	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
EPNHKGJO_04324	5.47e-117	-	-	-	P	-	-	-	Catalase
EPNHKGJO_04326	3.72e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
EPNHKGJO_04327	4.82e-103	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPNHKGJO_04328	4.11e-105	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
EPNHKGJO_04329	1e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
EPNHKGJO_04330	3.16e-222	-	-	-	-	-	-	-	-
EPNHKGJO_04333	2.16e-75	-	-	-	-	-	-	-	-
EPNHKGJO_04334	3.73e-113	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
EPNHKGJO_04335	3.7e-101	-	-	-	-	-	-	-	-
EPNHKGJO_04336	2.29e-261	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
EPNHKGJO_04337	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
EPNHKGJO_04338	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
EPNHKGJO_04339	4.25e-50	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
EPNHKGJO_04340	8.59e-266	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
EPNHKGJO_04341	1.04e-272	ywfA	-	-	EGP	-	-	-	-transporter
EPNHKGJO_04342	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EPNHKGJO_04343	3.31e-155	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EPNHKGJO_04344	1.1e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPNHKGJO_04345	3.03e-101	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EPNHKGJO_04346	8.75e-170	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
EPNHKGJO_04347	1.4e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
EPNHKGJO_04348	3.93e-223	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
EPNHKGJO_04349	3.07e-208	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
EPNHKGJO_04350	2.15e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EPNHKGJO_04351	4.83e-199	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
EPNHKGJO_04352	8.85e-142	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
EPNHKGJO_04353	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
EPNHKGJO_04354	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
EPNHKGJO_04355	8.53e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
EPNHKGJO_04356	3.15e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_04357	1.45e-298	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
EPNHKGJO_04360	1.23e-238	-	-	-	S	-	-	-	aspartate phosphatase
EPNHKGJO_04361	4.89e-108	yycN	-	-	K	-	-	-	Acetyltransferase
EPNHKGJO_04362	9.3e-167	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EPNHKGJO_04363	1.99e-262	yycP	-	-	-	-	-	-	-
EPNHKGJO_04364	5.22e-28	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
EPNHKGJO_04366	2.03e-294	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EPNHKGJO_04367	2.13e-36	-	-	-	-	-	-	-	-
EPNHKGJO_04369	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EPNHKGJO_04370	3.51e-212	-	-	-	-	-	-	-	-
EPNHKGJO_04371	6.42e-301	-	-	-	T	-	-	-	Putative serine esterase (DUF676)
EPNHKGJO_04372	9.72e-11	-	-	-	-	-	-	-	-
EPNHKGJO_04373	0.0	-	-	-	L	-	-	-	ATPase involved in DNA repair
EPNHKGJO_04374	2.3e-283	-	-	-	M	-	-	-	Pectate lyase superfamily protein
EPNHKGJO_04375	2.8e-169	-	-	-	-	-	-	-	-
EPNHKGJO_04376	1.05e-76	-	-	-	S	-	-	-	Pfam Transposase IS66
EPNHKGJO_04377	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPNHKGJO_04378	1.76e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
EPNHKGJO_04379	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
EPNHKGJO_04380	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
EPNHKGJO_04381	7.83e-123	ywhD	-	-	S	-	-	-	YwhD family
EPNHKGJO_04382	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
EPNHKGJO_04383	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EPNHKGJO_04384	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
EPNHKGJO_04385	7.14e-36	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
EPNHKGJO_04391	3.6e-152	-	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_04392	2.97e-07	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPNHKGJO_04393	6.95e-145	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
EPNHKGJO_04394	3.93e-65	-	-	-	S	-	-	-	DNA primase activity
EPNHKGJO_04395	1.94e-179	-	-	-	L	-	-	-	Participates in initiation and elongation during chromosome replication
EPNHKGJO_04403	0.000328	-	-	-	V	-	-	-	PFAM HNH endonuclease
EPNHKGJO_04406	7.44e-54	-	-	-	-	-	-	-	-
EPNHKGJO_04408	1.01e-40	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EPNHKGJO_04409	1.08e-16	larC	4.99.1.12	-	FJ	ko:K06898,ko:K09121,ko:K09705	-	ko00000,ko01000	Protein conserved in bacteria
EPNHKGJO_04413	1.83e-85	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
EPNHKGJO_04414	2.65e-159	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPNHKGJO_04415	4.43e-48	-	-	-	S	-	-	-	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
EPNHKGJO_04416	4.22e-203	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPNHKGJO_04418	5.54e-124	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPNHKGJO_04420	3.16e-88	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPNHKGJO_04421	2.65e-48	-	-	-	O	-	-	-	Glutaredoxin
EPNHKGJO_04422	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
EPNHKGJO_04423	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EPNHKGJO_04424	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPNHKGJO_04425	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPNHKGJO_04426	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_04427	4.01e-199	yycI	-	-	S	-	-	-	protein conserved in bacteria
EPNHKGJO_04428	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EPNHKGJO_04429	1.01e-273	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPNHKGJO_04430	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EPNHKGJO_04431	9.1e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
EPNHKGJO_04432	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
EPNHKGJO_04433	5.33e-212	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
EPNHKGJO_04442	1.02e-80	-	-	-	-	-	-	-	-
EPNHKGJO_04449	1.11e-315	-	-	-	-	-	-	-	-
EPNHKGJO_04455	5.01e-260	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EPNHKGJO_04456	8.87e-62	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
EPNHKGJO_04457	2.77e-26	-	-	-	-	-	-	-	-
EPNHKGJO_04458	1.92e-47	-	-	-	-	-	-	-	-
EPNHKGJO_04459	1.42e-09	-	-	-	S	-	-	-	YolD-like protein
EPNHKGJO_04461	6.46e-152	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
EPNHKGJO_04462	1.59e-65	-	-	-	L	-	-	-	Transposase
EPNHKGJO_04463	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
EPNHKGJO_04464	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
EPNHKGJO_04465	1.17e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EPNHKGJO_04466	7.4e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPNHKGJO_04467	1.09e-88	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
EPNHKGJO_04468	1.77e-306	-	-	-	L	ko:K06400	-	ko00000	Recombinase
EPNHKGJO_04470	6.78e-98	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EPNHKGJO_04471	1.28e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
EPNHKGJO_04473	2.5e-109	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
EPNHKGJO_04476	7.57e-208	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPNHKGJO_04477	5.24e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1643)
EPNHKGJO_04478	1.52e-62	-	-	-	-	-	-	-	-
EPNHKGJO_04481	1.68e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
EPNHKGJO_04482	6.53e-108	yuaE	-	-	S	-	-	-	DinB superfamily
EPNHKGJO_04483	5.57e-135	yuaD	-	-	-	-	-	-	-
EPNHKGJO_04484	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
EPNHKGJO_04485	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
EPNHKGJO_04486	8.33e-122	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
EPNHKGJO_04487	5.83e-118	yuaB	-	-	-	-	-	-	-
EPNHKGJO_04488	4.92e-139	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
EPNHKGJO_04489	2.21e-104	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
EPNHKGJO_04490	9.26e-123	-	-	-	S	ko:K21490	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
EPNHKGJO_04491	1.88e-162	-	-	-	UW	ko:K21487,ko:K21489,ko:K21491,ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
EPNHKGJO_04499	2.22e-65	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
EPNHKGJO_04501	1.07e-84	-	-	-	S	-	-	-	TIGRFAM germination protein, Ger(x)C family
EPNHKGJO_04502	1.23e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
EPNHKGJO_04503	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
EPNHKGJO_04504	4.94e-214	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
EPNHKGJO_04505	2.67e-57	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
EPNHKGJO_04506	6.76e-131	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
EPNHKGJO_04507	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
EPNHKGJO_04508	1.84e-85	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
EPNHKGJO_04509	9.24e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
EPNHKGJO_04510	4.61e-64	-	-	-	-	-	-	-	-
EPNHKGJO_04511	1.22e-88	-	-	-	-	-	-	-	-
EPNHKGJO_04513	1.29e-154	-	-	-	-	-	-	-	-
EPNHKGJO_04514	3.16e-102	-	-	-	-	-	-	-	-
EPNHKGJO_04515	1.09e-115	-	-	-	-	-	-	-	-
EPNHKGJO_04516	4.53e-75	-	-	-	-	-	-	-	-
EPNHKGJO_04517	4.99e-206	-	-	-	L	-	-	-	Domain of unknown function (DUF4942)
EPNHKGJO_04518	4.81e-50	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
EPNHKGJO_04519	1.1e-191	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
EPNHKGJO_04520	9.88e-91	-	-	-	-	-	-	-	-
EPNHKGJO_04521	1.36e-46	-	-	-	-	-	-	-	-
EPNHKGJO_04522	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EPNHKGJO_04523	1.46e-77	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
EPNHKGJO_04524	4.06e-149	yxaC	-	-	M	-	-	-	effector of murein hydrolase
EPNHKGJO_04525	1.13e-67	tmk	2.1.1.45, 2.7.4.9	-	F	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dTDP biosynthetic process
EPNHKGJO_04526	2.83e-116	yorS	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EPNHKGJO_04528	3.93e-93	-	-	-	S	-	-	-	Pfam Transposase IS66
EPNHKGJO_04529	7.62e-165	-	-	-	-	-	-	-	-
EPNHKGJO_04530	0.0	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
EPNHKGJO_04531	1.07e-53	-	-	-	-	-	-	-	-
EPNHKGJO_04532	3.38e-05	-	-	-	S	-	-	-	YopX protein
EPNHKGJO_04538	3.82e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
EPNHKGJO_04543	4.97e-96	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
EPNHKGJO_04544	2.49e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
EPNHKGJO_04545	1.92e-14	-	-	-	-	-	-	-	-
EPNHKGJO_04547	1.27e-37	bhlA	-	-	S	-	-	-	BhlA holin family
EPNHKGJO_04548	7.23e-36	-	-	-	S	-	-	-	SPP1 phage holin
EPNHKGJO_04550	1.07e-57	-	-	-	S	-	-	-	transposition, DNA-mediated
EPNHKGJO_04551	1.53e-148	-	-	-	S	-	-	-	HTH-like domain
EPNHKGJO_04557	7.18e-137	-	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EPNHKGJO_04559	4.76e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EPNHKGJO_04560	2.88e-56	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase