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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
KGCLDFHP_00001	6.46e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KGCLDFHP_00002	6.85e-132	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KGCLDFHP_00003	2.53e-139	-	-	-	S	-	-	-	SNARE associated Golgi protein
KGCLDFHP_00004	1.92e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KGCLDFHP_00005	5.7e-199	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
KGCLDFHP_00006	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
KGCLDFHP_00007	8.27e-227	-	-	-	-	-	-	-	-
KGCLDFHP_00008	2.14e-163	-	-	-	S	-	-	-	SNARE associated Golgi protein
KGCLDFHP_00009	9.25e-178	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KGCLDFHP_00010	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
KGCLDFHP_00011	3.1e-125	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGCLDFHP_00012	1.55e-204	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
KGCLDFHP_00013	1.86e-213	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
KGCLDFHP_00014	8.58e-103	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
KGCLDFHP_00015	1.68e-109	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
KGCLDFHP_00016	1.77e-98	yybA	-	-	K	-	-	-	Transcriptional regulator
KGCLDFHP_00017	4.76e-75	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
KGCLDFHP_00018	9.33e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGCLDFHP_00019	1.9e-313	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
KGCLDFHP_00020	2.39e-189	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGCLDFHP_00021	3.57e-201	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
KGCLDFHP_00022	8.41e-260	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
KGCLDFHP_00023	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KGCLDFHP_00024	4.84e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
KGCLDFHP_00025	4.36e-200	dkgB	-	-	S	-	-	-	reductase
KGCLDFHP_00026	1.67e-252	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
KGCLDFHP_00027	2.6e-231	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
KGCLDFHP_00028	1.62e-187	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KGCLDFHP_00029	1.69e-143	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
KGCLDFHP_00030	6.72e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
KGCLDFHP_00031	2.2e-312	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
KGCLDFHP_00032	2.3e-118	-	-	-	S	-	-	-	PAS domain
KGCLDFHP_00033	1.63e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
KGCLDFHP_00034	0.0	-	-	-	GM	ko:K13732	ko05100,map05100	ko00000,ko00001	domain, Protein
KGCLDFHP_00035	2.42e-69	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KGCLDFHP_00036	3.65e-52	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
KGCLDFHP_00037	4.66e-158	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
KGCLDFHP_00038	1.27e-164	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
KGCLDFHP_00039	1.31e-92	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KGCLDFHP_00040	3.28e-92	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
KGCLDFHP_00041	4.01e-181	-	-	-	S	-	-	-	PAS domain
KGCLDFHP_00042	2.08e-302	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KGCLDFHP_00043	3.03e-257	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
KGCLDFHP_00044	8.03e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KGCLDFHP_00045	1.27e-81	-	-	-	-	-	-	-	-
KGCLDFHP_00046	7.71e-186	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
KGCLDFHP_00047	2.27e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
KGCLDFHP_00048	1.02e-205	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KGCLDFHP_00049	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGCLDFHP_00050	1.19e-177	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
KGCLDFHP_00051	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KGCLDFHP_00052	8.26e-290	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KGCLDFHP_00053	1.14e-230	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
KGCLDFHP_00054	3.67e-184	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KGCLDFHP_00055	1.04e-172	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_00056	0.0	-	-	-	E	-	-	-	amino acid
KGCLDFHP_00057	8.98e-55	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
KGCLDFHP_00058	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KGCLDFHP_00059	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KGCLDFHP_00060	1.75e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KGCLDFHP_00061	5.18e-273	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KGCLDFHP_00062	3.03e-158	-	-	-	S	-	-	-	(CBS) domain
KGCLDFHP_00063	1.14e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KGCLDFHP_00064	4.45e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KGCLDFHP_00065	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KGCLDFHP_00066	3.62e-46	yabO	-	-	J	-	-	-	S4 domain protein
KGCLDFHP_00067	1.52e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
KGCLDFHP_00068	9.39e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
KGCLDFHP_00069	1.7e-311	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KGCLDFHP_00070	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KGCLDFHP_00071	0.0	-	-	-	S	-	-	-	membrane
KGCLDFHP_00072	0.0	-	-	-	S	-	-	-	membrane
KGCLDFHP_00073	4.49e-143	-	-	-	L	-	-	-	Resolvase, N-terminal
KGCLDFHP_00074	2.46e-269	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
KGCLDFHP_00075	1.92e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KGCLDFHP_00076	2.17e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KGCLDFHP_00077	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
KGCLDFHP_00079	2.5e-15	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
KGCLDFHP_00081	7.76e-59	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
KGCLDFHP_00082	8.8e-119	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KGCLDFHP_00083	2.24e-76	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KGCLDFHP_00084	1.86e-84	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KGCLDFHP_00088	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KGCLDFHP_00089	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGCLDFHP_00090	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGCLDFHP_00092	8.64e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KGCLDFHP_00093	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KGCLDFHP_00094	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
KGCLDFHP_00095	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
KGCLDFHP_00096	1.38e-175	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
KGCLDFHP_00097	2.36e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KGCLDFHP_00098	2.05e-115	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KGCLDFHP_00099	2.02e-221	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
KGCLDFHP_00100	1.09e-76	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
KGCLDFHP_00101	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
KGCLDFHP_00102	3.44e-200	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KGCLDFHP_00103	9.17e-70	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KGCLDFHP_00104	8.64e-196	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KGCLDFHP_00105	6.14e-155	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
KGCLDFHP_00106	3.17e-202	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KGCLDFHP_00107	7.69e-134	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KGCLDFHP_00108	4.55e-12	-	-	-	-	-	-	-	-
KGCLDFHP_00109	1.39e-181	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
KGCLDFHP_00110	3.13e-98	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
KGCLDFHP_00111	2.62e-282	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KGCLDFHP_00112	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KGCLDFHP_00113	2.58e-313	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
KGCLDFHP_00114	8.26e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KGCLDFHP_00115	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KGCLDFHP_00116	1.91e-85	-	-	-	-	-	-	-	-
KGCLDFHP_00117	6.78e-220	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
KGCLDFHP_00118	3.6e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KGCLDFHP_00119	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
KGCLDFHP_00120	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
KGCLDFHP_00121	3.61e-244	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
KGCLDFHP_00122	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
KGCLDFHP_00123	2.09e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KGCLDFHP_00124	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KGCLDFHP_00125	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KGCLDFHP_00126	1.74e-117	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KGCLDFHP_00127	2.94e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KGCLDFHP_00128	9.46e-200	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KGCLDFHP_00129	2.33e-87	-	-	-	L	-	-	-	nuclease
KGCLDFHP_00130	7.26e-183	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
KGCLDFHP_00131	2e-64	-	-	-	K	-	-	-	Helix-turn-helix domain
KGCLDFHP_00132	4.2e-240	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KGCLDFHP_00133	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
KGCLDFHP_00134	6.36e-37	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
KGCLDFHP_00135	2.48e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KGCLDFHP_00136	1.03e-131	-	-	-	I	-	-	-	PAP2 superfamily
KGCLDFHP_00137	7.18e-189	pbpX2	-	-	V	-	-	-	Beta-lactamase
KGCLDFHP_00138	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KGCLDFHP_00139	5.16e-50	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGCLDFHP_00140	4.7e-303	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
KGCLDFHP_00141	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGCLDFHP_00142	9.7e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
KGCLDFHP_00143	6.13e-52	-	-	-	-	-	-	-	-
KGCLDFHP_00144	2.57e-272	-	-	-	S	-	-	-	Membrane
KGCLDFHP_00146	1.18e-78	-	-	-	-	-	-	-	-
KGCLDFHP_00147	1.88e-66	-	-	-	-	-	-	-	-
KGCLDFHP_00148	5.45e-61	-	-	-	-	-	-	-	-
KGCLDFHP_00149	1.66e-111	ykuL	-	-	S	-	-	-	(CBS) domain
KGCLDFHP_00150	0.0	cadA	-	-	P	-	-	-	P-type ATPase
KGCLDFHP_00151	1.19e-258	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
KGCLDFHP_00152	1.81e-141	-	-	-	S	-	-	-	Putative adhesin
KGCLDFHP_00153	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
KGCLDFHP_00154	2.24e-204	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGCLDFHP_00155	2.33e-47	-	-	-	-	-	-	-	-
KGCLDFHP_00156	2.07e-155	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KGCLDFHP_00157	5.84e-201	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
KGCLDFHP_00158	7.06e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
KGCLDFHP_00159	2.11e-113	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
KGCLDFHP_00162	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
KGCLDFHP_00163	1.86e-124	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
KGCLDFHP_00164	4.83e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KGCLDFHP_00165	3.18e-261	-	-	-	S	-	-	-	DUF218 domain
KGCLDFHP_00166	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_00167	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
KGCLDFHP_00168	1.9e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
KGCLDFHP_00169	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KGCLDFHP_00170	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KGCLDFHP_00171	4.96e-226	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
KGCLDFHP_00172	1.21e-215	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
KGCLDFHP_00173	1.75e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
KGCLDFHP_00174	4.62e-192	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KGCLDFHP_00175	2.55e-247	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
KGCLDFHP_00176	1.06e-203	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KGCLDFHP_00177	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGCLDFHP_00178	5.37e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KGCLDFHP_00179	8.84e-207	-	-	-	S	-	-	-	Aldo/keto reductase family
KGCLDFHP_00180	9.42e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KGCLDFHP_00181	8.43e-155	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
KGCLDFHP_00182	4e-162	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
KGCLDFHP_00183	1.58e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
KGCLDFHP_00184	1.26e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
KGCLDFHP_00185	2.02e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
KGCLDFHP_00186	3.74e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KGCLDFHP_00187	0.0	ycaM	-	-	E	-	-	-	amino acid
KGCLDFHP_00189	3.72e-238	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
KGCLDFHP_00190	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KGCLDFHP_00191	7.02e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
KGCLDFHP_00192	5.9e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KGCLDFHP_00193	1.18e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KGCLDFHP_00194	7.52e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
KGCLDFHP_00195	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KGCLDFHP_00196	1.46e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KGCLDFHP_00197	6.82e-139	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
KGCLDFHP_00198	2.21e-110	-	-	-	-	-	-	-	-
KGCLDFHP_00199	2.08e-122	-	-	-	-	-	-	-	-
KGCLDFHP_00200	6.67e-202	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KGCLDFHP_00201	1.02e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KGCLDFHP_00202	4.47e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
KGCLDFHP_00203	1.75e-110	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
KGCLDFHP_00204	6.4e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KGCLDFHP_00205	1.12e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
KGCLDFHP_00206	2.41e-260	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KGCLDFHP_00207	2.51e-172	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KGCLDFHP_00208	1.08e-175	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KGCLDFHP_00209	8.14e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGCLDFHP_00210	6.38e-197	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KGCLDFHP_00211	1.33e-225	ybbR	-	-	S	-	-	-	YbbR-like protein
KGCLDFHP_00212	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KGCLDFHP_00213	2.8e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KGCLDFHP_00214	3.02e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KGCLDFHP_00215	1.44e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KGCLDFHP_00216	1.42e-255	-	-	-	S	-	-	-	Putative adhesin
KGCLDFHP_00217	5.95e-149	-	-	-	-	-	-	-	-
KGCLDFHP_00218	5.93e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase family
KGCLDFHP_00219	8.84e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KGCLDFHP_00220	1.75e-275	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KGCLDFHP_00221	3.59e-123	-	-	-	S	-	-	-	VanZ like family
KGCLDFHP_00222	6.1e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
KGCLDFHP_00223	6.35e-230	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
KGCLDFHP_00224	8.54e-223	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
KGCLDFHP_00225	9.23e-55	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
KGCLDFHP_00226	3.97e-77	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
KGCLDFHP_00228	8.81e-114	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
KGCLDFHP_00229	4.19e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
KGCLDFHP_00230	9.62e-289	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KGCLDFHP_00233	8.93e-130	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
KGCLDFHP_00234	1.22e-54	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KGCLDFHP_00235	5.72e-104	-	-	-	K	-	-	-	LytTr DNA-binding domain
KGCLDFHP_00236	6.76e-168	-	-	-	S	-	-	-	membrane
KGCLDFHP_00238	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KGCLDFHP_00239	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KGCLDFHP_00240	1.77e-139	-	-	-	-	-	-	-	-
KGCLDFHP_00241	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
KGCLDFHP_00242	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KGCLDFHP_00243	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KGCLDFHP_00244	3.1e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KGCLDFHP_00245	3.28e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KGCLDFHP_00246	6.84e-75	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
KGCLDFHP_00247	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KGCLDFHP_00248	6.98e-265	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KGCLDFHP_00249	1.24e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
KGCLDFHP_00250	1.61e-294	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KGCLDFHP_00251	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KGCLDFHP_00252	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
KGCLDFHP_00253	1.01e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KGCLDFHP_00254	3.49e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
KGCLDFHP_00255	1.96e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
KGCLDFHP_00256	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KGCLDFHP_00257	8.93e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KGCLDFHP_00258	3.65e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
KGCLDFHP_00259	1.23e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
KGCLDFHP_00260	3.6e-152	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KGCLDFHP_00261	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KGCLDFHP_00262	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KGCLDFHP_00263	3.86e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
KGCLDFHP_00264	4.59e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KGCLDFHP_00265	1.15e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KGCLDFHP_00266	1.22e-48	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
KGCLDFHP_00267	1.91e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
KGCLDFHP_00268	9.02e-317	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KGCLDFHP_00269	2.27e-222	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KGCLDFHP_00270	6.82e-224	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
KGCLDFHP_00271	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
KGCLDFHP_00272	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
KGCLDFHP_00273	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
KGCLDFHP_00274	4.64e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
KGCLDFHP_00275	1.36e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGCLDFHP_00276	7.34e-290	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGCLDFHP_00277	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGCLDFHP_00278	3.99e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KGCLDFHP_00279	3.19e-53	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
KGCLDFHP_00280	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
KGCLDFHP_00281	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KGCLDFHP_00282	7.07e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
KGCLDFHP_00283	1.03e-90	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KGCLDFHP_00284	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KGCLDFHP_00285	4.39e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KGCLDFHP_00286	1.6e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
KGCLDFHP_00287	1.17e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KGCLDFHP_00288	2.16e-167	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
KGCLDFHP_00289	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
KGCLDFHP_00290	3.64e-76	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KGCLDFHP_00291	2.63e-239	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KGCLDFHP_00293	2.91e-139	-	-	-	K	-	-	-	transcriptional regulator
KGCLDFHP_00294	1.79e-122	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
KGCLDFHP_00295	4.22e-219	-	-	-	K	-	-	-	Helix-turn-helix
KGCLDFHP_00296	3.76e-145	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KGCLDFHP_00297	2.31e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGCLDFHP_00298	1.3e-86	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
KGCLDFHP_00299	7.69e-278	-	-	-	S	-	-	-	Membrane
KGCLDFHP_00300	9.28e-79	-	-	-	S	-	-	-	YjcQ protein
KGCLDFHP_00301	2.5e-47	-	-	-	-	-	-	-	-
KGCLDFHP_00302	0.0	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
KGCLDFHP_00303	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
KGCLDFHP_00304	9.85e-317	yqaT	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
KGCLDFHP_00305	2.95e-101	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
KGCLDFHP_00310	2.15e-101	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
KGCLDFHP_00317	3.87e-133	-	-	-	-	-	-	-	-
KGCLDFHP_00320	3.39e-38	-	-	-	S	-	-	-	sequence-specific DNA binding
KGCLDFHP_00321	1.14e-40	-	-	-	K	-	-	-	Helix-turn-helix domain
KGCLDFHP_00322	8.54e-147	-	-	-	S	-	-	-	ERF superfamily
KGCLDFHP_00323	1.69e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
KGCLDFHP_00324	6.63e-26	-	-	-	-	-	-	-	-
KGCLDFHP_00325	1.18e-24	-	-	-	-	-	-	-	-
KGCLDFHP_00326	1.09e-42	-	-	-	-	-	-	-	-
KGCLDFHP_00328	4.22e-41	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
KGCLDFHP_00331	3.69e-38	-	-	-	-	-	-	-	-
KGCLDFHP_00332	1.13e-100	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
KGCLDFHP_00333	0.000669	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGCLDFHP_00334	8.16e-37	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGCLDFHP_00335	3.92e-61	-	-	-	E	-	-	-	Zn peptidase
KGCLDFHP_00336	2.92e-83	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
KGCLDFHP_00337	5.48e-27	-	-	-	-	-	-	-	-
KGCLDFHP_00338	5.3e-133	-	-	-	-	-	-	-	-
KGCLDFHP_00339	1.4e-280	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KGCLDFHP_00340	2.04e-132	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KGCLDFHP_00341	5.14e-77	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
KGCLDFHP_00342	8.88e-18	-	-	-	-	-	-	-	-
KGCLDFHP_00344	1.31e-59	-	-	-	-	-	-	-	-
KGCLDFHP_00346	1.65e-127	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
KGCLDFHP_00347	1.46e-64	-	-	-	-	-	-	-	-
KGCLDFHP_00348	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
KGCLDFHP_00349	7.39e-185	-	-	-	S	-	-	-	phage tail
KGCLDFHP_00350	0.0	-	-	-	D	-	-	-	SLT domain
KGCLDFHP_00353	8.25e-131	-	-	-	S	-	-	-	Phage tail tube protein
KGCLDFHP_00355	2.46e-58	-	-	-	S	-	-	-	exonuclease activity
KGCLDFHP_00357	5.31e-82	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
KGCLDFHP_00358	1.59e-216	-	-	-	-	-	-	-	-
KGCLDFHP_00359	9.09e-114	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
KGCLDFHP_00360	4.59e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KGCLDFHP_00361	7.58e-210	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
KGCLDFHP_00362	4.41e-131	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
KGCLDFHP_00363	2.68e-154	-	-	-	S	-	-	-	Peptidase_C39 like family
KGCLDFHP_00364	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
KGCLDFHP_00365	5.92e-150	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
KGCLDFHP_00367	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
KGCLDFHP_00368	3.25e-185	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KGCLDFHP_00369	1.14e-164	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KGCLDFHP_00370	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KGCLDFHP_00371	3.39e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
KGCLDFHP_00372	1.65e-69	-	-	-	-	-	-	-	-
KGCLDFHP_00373	9.27e-36	-	-	-	-	-	-	-	-
KGCLDFHP_00374	4.36e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
KGCLDFHP_00375	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KGCLDFHP_00376	2.68e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_00377	0.0	-	-	-	E	-	-	-	Amino Acid
KGCLDFHP_00378	3.69e-296	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KGCLDFHP_00379	8.6e-292	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
KGCLDFHP_00380	1.43e-161	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
KGCLDFHP_00381	3.24e-126	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
KGCLDFHP_00382	1.87e-58	-	-	-	-	-	-	-	-
KGCLDFHP_00383	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
KGCLDFHP_00384	2.23e-142	-	-	-	-	-	-	-	-
KGCLDFHP_00385	1.35e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
KGCLDFHP_00386	3.35e-228	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KGCLDFHP_00387	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KGCLDFHP_00388	9.16e-138	vanZ	-	-	V	-	-	-	VanZ like family
KGCLDFHP_00389	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
KGCLDFHP_00390	7.02e-311	-	-	-	EGP	-	-	-	Major Facilitator
KGCLDFHP_00391	3.21e-89	-	-	-	-	-	-	-	-
KGCLDFHP_00394	7.92e-247	ampC	-	-	V	-	-	-	Beta-lactamase
KGCLDFHP_00395	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
KGCLDFHP_00396	8.2e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
KGCLDFHP_00397	4.43e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KGCLDFHP_00398	5.31e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KGCLDFHP_00399	8.5e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KGCLDFHP_00400	2.61e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KGCLDFHP_00401	7.4e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
KGCLDFHP_00402	1.75e-35	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KGCLDFHP_00403	5.6e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KGCLDFHP_00404	1.13e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KGCLDFHP_00405	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KGCLDFHP_00406	1.21e-219	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KGCLDFHP_00407	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KGCLDFHP_00408	2.1e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
KGCLDFHP_00409	3.07e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
KGCLDFHP_00410	3.53e-229	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
KGCLDFHP_00411	3.34e-18	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
KGCLDFHP_00412	5.54e-69	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
KGCLDFHP_00413	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
KGCLDFHP_00414	1.85e-284	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
KGCLDFHP_00415	3.52e-106	uspA	-	-	T	-	-	-	universal stress protein
KGCLDFHP_00416	9.34e-08	-	-	-	-	-	-	-	-
KGCLDFHP_00417	3.91e-305	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
KGCLDFHP_00418	6.16e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KGCLDFHP_00419	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KGCLDFHP_00421	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KGCLDFHP_00422	8.66e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
KGCLDFHP_00423	4.43e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KGCLDFHP_00424	3.13e-159	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KGCLDFHP_00425	1.91e-230	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
KGCLDFHP_00426	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
KGCLDFHP_00427	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KGCLDFHP_00428	1.35e-300	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KGCLDFHP_00429	2.59e-159	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
KGCLDFHP_00430	9.17e-144	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
KGCLDFHP_00431	3.11e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
KGCLDFHP_00432	1.17e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
KGCLDFHP_00433	3.99e-123	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
KGCLDFHP_00434	2.36e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
KGCLDFHP_00435	2.2e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
KGCLDFHP_00436	1.89e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
KGCLDFHP_00437	1.02e-229	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KGCLDFHP_00438	3.95e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
KGCLDFHP_00439	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KGCLDFHP_00440	9e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KGCLDFHP_00441	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KGCLDFHP_00442	9.56e-266	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KGCLDFHP_00443	4.49e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KGCLDFHP_00444	5.2e-309	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KGCLDFHP_00445	3.29e-313	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KGCLDFHP_00446	9.26e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KGCLDFHP_00447	1.36e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
KGCLDFHP_00448	1.39e-187	ylmH	-	-	S	-	-	-	S4 domain protein
KGCLDFHP_00449	4.46e-162	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
KGCLDFHP_00450	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KGCLDFHP_00451	1.37e-45	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
KGCLDFHP_00452	2.57e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
KGCLDFHP_00453	6.32e-52	-	-	-	-	-	-	-	-
KGCLDFHP_00454	1.02e-164	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KGCLDFHP_00455	3.68e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
KGCLDFHP_00456	1.27e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
KGCLDFHP_00457	9.01e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KGCLDFHP_00458	5.5e-162	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
KGCLDFHP_00459	3.57e-151	-	-	-	S	-	-	-	repeat protein
KGCLDFHP_00460	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KGCLDFHP_00461	6.58e-225	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
KGCLDFHP_00462	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KGCLDFHP_00463	3.08e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
KGCLDFHP_00464	9.73e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KGCLDFHP_00465	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
KGCLDFHP_00466	1.36e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
KGCLDFHP_00467	4e-66	ylbG	-	-	S	-	-	-	UPF0298 protein
KGCLDFHP_00468	1.23e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
KGCLDFHP_00469	3.34e-112	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KGCLDFHP_00470	6.91e-235	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
KGCLDFHP_00471	7.81e-141	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
KGCLDFHP_00472	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
KGCLDFHP_00473	3.38e-227	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
KGCLDFHP_00474	1.8e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
KGCLDFHP_00475	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KGCLDFHP_00476	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KGCLDFHP_00477	9.52e-205	-	-	-	-	-	-	-	-
KGCLDFHP_00478	2.45e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KGCLDFHP_00479	1.21e-276	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KGCLDFHP_00480	3.55e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KGCLDFHP_00481	1.26e-132	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
KGCLDFHP_00482	1.62e-115	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KGCLDFHP_00483	1.1e-108	-	-	-	-	-	-	-	-
KGCLDFHP_00485	5.91e-151	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
KGCLDFHP_00486	5.18e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
KGCLDFHP_00487	3.45e-283	-	-	-	-	-	-	-	-
KGCLDFHP_00488	1.39e-156	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
KGCLDFHP_00489	1.53e-209	-	-	-	-	-	-	-	-
KGCLDFHP_00490	8.59e-103	-	-	-	K	-	-	-	DNA-templated transcription, initiation
KGCLDFHP_00491	1.74e-211	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KGCLDFHP_00492	9.04e-179	epsB	-	-	M	-	-	-	biosynthesis protein
KGCLDFHP_00493	1.69e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
KGCLDFHP_00494	3.8e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
KGCLDFHP_00495	4.19e-104	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
KGCLDFHP_00496	2.29e-176	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
KGCLDFHP_00497	3.11e-156	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
KGCLDFHP_00498	1.92e-48	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
KGCLDFHP_00499	7.92e-64	-	-	-	M	-	-	-	Glycosyltransferase like family 2
KGCLDFHP_00500	1.53e-58	-	-	-	G	-	-	-	Protein of unknown function (DUF563)
KGCLDFHP_00501	2.79e-80	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
KGCLDFHP_00502	5.75e-127	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
KGCLDFHP_00503	4.68e-56	-	-	-	H	-	-	-	Core-2/I-Branching enzyme
KGCLDFHP_00504	2.1e-270	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
KGCLDFHP_00505	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
KGCLDFHP_00506	3.85e-210	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KGCLDFHP_00507	6.86e-73	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KGCLDFHP_00510	6.6e-07	-	-	-	-	-	-	-	-
KGCLDFHP_00511	6.4e-281	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
KGCLDFHP_00512	6.41e-265	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KGCLDFHP_00513	2.53e-209	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KGCLDFHP_00514	1.21e-152	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KGCLDFHP_00515	1.11e-236	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KGCLDFHP_00516	7.56e-101	-	-	-	S	-	-	-	AAA ATPase domain
KGCLDFHP_00517	1.3e-111	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	DNA mismatch endonuclease Vsr
KGCLDFHP_00518	2.74e-08	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KGCLDFHP_00519	3.1e-15	-	-	-	S	-	-	-	FRG
KGCLDFHP_00521	1.88e-47	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KGCLDFHP_00522	6.12e-162	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGCLDFHP_00523	4.22e-34	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
KGCLDFHP_00524	5.36e-297	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KGCLDFHP_00525	1.25e-135	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
KGCLDFHP_00526	8.21e-136	-	-	-	-	-	-	-	-
KGCLDFHP_00527	5.82e-130	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
KGCLDFHP_00528	4.01e-207	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
KGCLDFHP_00530	5.83e-172	-	-	-	-	-	-	-	-
KGCLDFHP_00531	4.42e-105	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
KGCLDFHP_00532	3.78e-92	-	-	-	-	-	-	-	-
KGCLDFHP_00533	1.48e-90	-	-	-	-	-	-	-	-
KGCLDFHP_00534	6.93e-88	-	-	-	S	-	-	-	Domain of unknown function DUF1828
KGCLDFHP_00535	8.94e-161	-	-	-	S	-	-	-	Rib/alpha-like repeat
KGCLDFHP_00536	2.03e-09	-	-	-	-	-	-	-	-
KGCLDFHP_00537	1.06e-314	yagE	-	-	E	-	-	-	amino acid
KGCLDFHP_00538	5.48e-150	-	-	-	GM	-	-	-	NmrA-like family
KGCLDFHP_00539	1.15e-195	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
KGCLDFHP_00540	3.55e-132	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
KGCLDFHP_00541	8.28e-222	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
KGCLDFHP_00542	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KGCLDFHP_00543	7.6e-306	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KGCLDFHP_00544	0.0	oatA	-	-	I	-	-	-	Acyltransferase
KGCLDFHP_00545	6.85e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KGCLDFHP_00546	7.14e-185	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
KGCLDFHP_00547	8.03e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
KGCLDFHP_00548	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
KGCLDFHP_00549	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KGCLDFHP_00550	7.45e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
KGCLDFHP_00551	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
KGCLDFHP_00552	1.69e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KGCLDFHP_00553	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
KGCLDFHP_00554	3.33e-211	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
KGCLDFHP_00555	1.59e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
KGCLDFHP_00556	1.95e-82	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
KGCLDFHP_00557	1.23e-172	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KGCLDFHP_00558	1.59e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KGCLDFHP_00559	4.82e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KGCLDFHP_00560	1.08e-117	-	-	-	M	-	-	-	Lysin motif
KGCLDFHP_00561	2.31e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KGCLDFHP_00562	1.78e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
KGCLDFHP_00563	6.93e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
KGCLDFHP_00564	1.28e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
KGCLDFHP_00565	1.37e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KGCLDFHP_00566	2.89e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
KGCLDFHP_00567	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
KGCLDFHP_00568	3.21e-175	-	-	-	S	-	-	-	SIR2-like domain
KGCLDFHP_00569	4.78e-53	-	-	-	S	-	-	-	SIR2-like domain
KGCLDFHP_00570	5.77e-193	-	-	-	-	-	-	-	-
KGCLDFHP_00571	1.46e-134	-	-	-	J	ko:K10716	-	ko00000,ko02000	Ion transport protein
KGCLDFHP_00572	4.7e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KGCLDFHP_00573	2.86e-288	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KGCLDFHP_00574	2.78e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
KGCLDFHP_00575	7.72e-195	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
KGCLDFHP_00576	3.74e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
KGCLDFHP_00577	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
KGCLDFHP_00578	1.64e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KGCLDFHP_00579	1.49e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KGCLDFHP_00580	1.39e-195	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
KGCLDFHP_00581	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KGCLDFHP_00582	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KGCLDFHP_00583	5.79e-217	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
KGCLDFHP_00584	1.9e-115	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KGCLDFHP_00585	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KGCLDFHP_00586	5.87e-229	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
KGCLDFHP_00587	7.43e-131	-	-	-	K	-	-	-	LysR substrate binding domain
KGCLDFHP_00588	5.82e-130	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
KGCLDFHP_00590	2.6e-96	-	-	-	-	-	-	-	-
KGCLDFHP_00591	1.73e-227	-	-	-	S	-	-	-	Conserved hypothetical protein 698
KGCLDFHP_00593	2.81e-139	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
KGCLDFHP_00594	3.1e-177	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
KGCLDFHP_00595	1.25e-107	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
KGCLDFHP_00596	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
KGCLDFHP_00597	1.76e-175	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
KGCLDFHP_00598	7.2e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
KGCLDFHP_00599	3.12e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
KGCLDFHP_00600	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
KGCLDFHP_00601	2.7e-139	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
KGCLDFHP_00602	3.46e-15	-	-	-	S	-	-	-	reductase
KGCLDFHP_00603	9.63e-70	-	-	-	S	-	-	-	reductase
KGCLDFHP_00604	6.22e-140	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
KGCLDFHP_00605	3.45e-150	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
KGCLDFHP_00606	7.15e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
KGCLDFHP_00607	3.02e-308	-	-	-	T	-	-	-	GHKL domain
KGCLDFHP_00608	4.05e-119	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KGCLDFHP_00609	3.38e-87	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KGCLDFHP_00610	4.36e-120	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KGCLDFHP_00611	1.18e-41	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
KGCLDFHP_00612	3.23e-315	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KGCLDFHP_00613	3.27e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KGCLDFHP_00614	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KGCLDFHP_00615	3.31e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KGCLDFHP_00616	9.79e-296	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KGCLDFHP_00617	1.18e-226	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
KGCLDFHP_00618	3.04e-119	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KGCLDFHP_00619	6.47e-214	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KGCLDFHP_00620	7.14e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KGCLDFHP_00621	9.13e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KGCLDFHP_00622	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
KGCLDFHP_00623	1.1e-191	yxeH	-	-	S	-	-	-	hydrolase
KGCLDFHP_00624	1.32e-228	-	-	-	S	-	-	-	DUF218 domain
KGCLDFHP_00625	2.14e-64	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
KGCLDFHP_00626	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
KGCLDFHP_00627	2.18e-221	-	-	-	-	-	-	-	-
KGCLDFHP_00628	1.28e-167	-	-	-	-	-	-	-	-
KGCLDFHP_00629	2.02e-131	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KGCLDFHP_00630	5.06e-31	-	-	-	-	-	-	-	-
KGCLDFHP_00631	2.65e-108	-	-	-	L	-	-	-	transposase activity
KGCLDFHP_00632	9.27e-15	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
KGCLDFHP_00633	4.93e-82	-	-	-	-	-	-	-	-
KGCLDFHP_00634	1.1e-49	-	-	-	-	-	-	-	-
KGCLDFHP_00635	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
KGCLDFHP_00636	2.06e-192	-	-	-	-	-	-	-	-
KGCLDFHP_00637	6.46e-49	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
KGCLDFHP_00638	3.06e-177	-	-	-	-	-	-	-	-
KGCLDFHP_00639	3.51e-184	-	-	-	-	-	-	-	-
KGCLDFHP_00640	6.31e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KGCLDFHP_00641	4.24e-78	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
KGCLDFHP_00642	5.38e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
KGCLDFHP_00643	1.35e-194	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KGCLDFHP_00644	4.62e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
KGCLDFHP_00645	4.82e-193	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KGCLDFHP_00646	3.81e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_00647	7.1e-152	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
KGCLDFHP_00648	6.84e-147	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
KGCLDFHP_00649	1.84e-151	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
KGCLDFHP_00650	1.08e-286	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
KGCLDFHP_00651	1.84e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
KGCLDFHP_00652	3.97e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KGCLDFHP_00653	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KGCLDFHP_00654	3.56e-235	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KGCLDFHP_00655	3.73e-40	-	-	-	-	-	-	-	-
KGCLDFHP_00656	6.07e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KGCLDFHP_00657	2.16e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KGCLDFHP_00658	1.29e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
KGCLDFHP_00659	1.05e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KGCLDFHP_00660	7.28e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KGCLDFHP_00661	4.7e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
KGCLDFHP_00662	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
KGCLDFHP_00663	1.36e-241	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KGCLDFHP_00664	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
KGCLDFHP_00665	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
KGCLDFHP_00666	1.36e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KGCLDFHP_00667	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
KGCLDFHP_00668	1.94e-246	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KGCLDFHP_00669	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KGCLDFHP_00670	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KGCLDFHP_00671	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KGCLDFHP_00672	2.04e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
KGCLDFHP_00673	1.33e-188	-	-	-	S	-	-	-	hydrolase
KGCLDFHP_00675	1.47e-212	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
KGCLDFHP_00676	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KGCLDFHP_00677	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KGCLDFHP_00678	3.17e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KGCLDFHP_00679	2.62e-263	camS	-	-	S	-	-	-	sex pheromone
KGCLDFHP_00680	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KGCLDFHP_00681	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
KGCLDFHP_00682	5.71e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
KGCLDFHP_00683	4.82e-131	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
KGCLDFHP_00685	4.53e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
KGCLDFHP_00686	1.34e-169	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
KGCLDFHP_00687	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
KGCLDFHP_00688	9.14e-286	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KGCLDFHP_00689	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
KGCLDFHP_00690	0.0	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
KGCLDFHP_00691	9.12e-199	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KGCLDFHP_00692	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KGCLDFHP_00693	0.0	-	-	-	S	-	-	-	Glycosyltransferase like family 2
KGCLDFHP_00694	2.43e-264	-	-	-	M	-	-	-	Glycosyl transferases group 1
KGCLDFHP_00695	6.86e-174	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KGCLDFHP_00696	1.44e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
KGCLDFHP_00697	2.57e-158	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
KGCLDFHP_00698	2.15e-243	-	-	-	-	-	-	-	-
KGCLDFHP_00699	1.7e-56	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
KGCLDFHP_00700	2.36e-51	-	-	-	-	-	-	-	-
KGCLDFHP_00701	1.44e-17	-	-	-	-	-	-	-	-
KGCLDFHP_00702	3.24e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KGCLDFHP_00703	6.92e-236	-	-	-	S	-	-	-	AAA domain
KGCLDFHP_00704	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KGCLDFHP_00705	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
KGCLDFHP_00706	5.37e-271	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
KGCLDFHP_00707	0.0	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
KGCLDFHP_00708	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
KGCLDFHP_00709	5.26e-200	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
KGCLDFHP_00710	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KGCLDFHP_00711	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KGCLDFHP_00712	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KGCLDFHP_00713	2.87e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KGCLDFHP_00714	1.15e-153	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KGCLDFHP_00715	6e-212	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KGCLDFHP_00716	5.4e-140	yjbH	-	-	Q	-	-	-	Thioredoxin
KGCLDFHP_00717	2.51e-143	-	-	-	S	-	-	-	CYTH
KGCLDFHP_00718	1.7e-146	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
KGCLDFHP_00719	3.58e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KGCLDFHP_00720	1.08e-217	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KGCLDFHP_00721	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
KGCLDFHP_00722	6.98e-306	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
KGCLDFHP_00723	6.1e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
KGCLDFHP_00724	1.2e-88	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
KGCLDFHP_00725	8.89e-269	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
KGCLDFHP_00726	8e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KGCLDFHP_00727	1.96e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
KGCLDFHP_00728	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KGCLDFHP_00729	4.09e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
KGCLDFHP_00730	4.65e-296	ymfH	-	-	S	-	-	-	Peptidase M16
KGCLDFHP_00731	1.05e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
KGCLDFHP_00732	1.48e-178	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
KGCLDFHP_00733	7.62e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KGCLDFHP_00734	2.99e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KGCLDFHP_00735	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
KGCLDFHP_00736	9.48e-262	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
KGCLDFHP_00737	1.16e-140	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
KGCLDFHP_00738	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KGCLDFHP_00739	8.05e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KGCLDFHP_00740	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KGCLDFHP_00741	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
KGCLDFHP_00742	3.57e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KGCLDFHP_00743	1.57e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
KGCLDFHP_00744	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KGCLDFHP_00745	1.99e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KGCLDFHP_00746	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KGCLDFHP_00747	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KGCLDFHP_00748	3.69e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KGCLDFHP_00749	3e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KGCLDFHP_00750	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
KGCLDFHP_00751	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KGCLDFHP_00752	6.02e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KGCLDFHP_00753	1.18e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KGCLDFHP_00754	6.1e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KGCLDFHP_00755	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KGCLDFHP_00756	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KGCLDFHP_00757	3.04e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KGCLDFHP_00758	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KGCLDFHP_00759	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KGCLDFHP_00760	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
KGCLDFHP_00761	5.78e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KGCLDFHP_00762	1.2e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KGCLDFHP_00763	4.87e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KGCLDFHP_00764	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KGCLDFHP_00765	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
KGCLDFHP_00766	1.92e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KGCLDFHP_00767	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KGCLDFHP_00768	7.63e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGCLDFHP_00769	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
KGCLDFHP_00770	4.31e-195	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGCLDFHP_00771	3.43e-204	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGCLDFHP_00772	7.2e-262	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
KGCLDFHP_00773	2.37e-179	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGCLDFHP_00774	1.29e-191	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KGCLDFHP_00775	1.08e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KGCLDFHP_00776	1.13e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
KGCLDFHP_00777	8.5e-85	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KGCLDFHP_00779	0.0	-	-	-	S	-	-	-	M26 IgA1-specific Metallo-endopeptidase C-terminal region
KGCLDFHP_00780	1.42e-101	-	-	-	L	-	-	-	NUDIX domain
KGCLDFHP_00781	6.08e-180	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
KGCLDFHP_00782	1.13e-248	flp	-	-	V	-	-	-	Beta-lactamase
KGCLDFHP_00784	1.77e-51	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
KGCLDFHP_00785	5.03e-148	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
KGCLDFHP_00786	2.49e-121	dpsB	-	-	P	-	-	-	Belongs to the Dps family
KGCLDFHP_00787	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
KGCLDFHP_00788	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
KGCLDFHP_00789	1.26e-140	-	-	-	-	-	-	-	-
KGCLDFHP_00790	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KGCLDFHP_00791	2.58e-155	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
KGCLDFHP_00792	3.28e-166	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_00793	1.56e-311	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
KGCLDFHP_00794	5.12e-207	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
KGCLDFHP_00795	2.56e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
KGCLDFHP_00796	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_00797	2.1e-183	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
KGCLDFHP_00798	3.82e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KGCLDFHP_00799	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KGCLDFHP_00800	4.72e-134	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
KGCLDFHP_00802	1.09e-61	-	-	-	S	-	-	-	Enterocin A Immunity
KGCLDFHP_00803	8.17e-285	-	-	-	S	-	-	-	CAAX protease self-immunity
KGCLDFHP_00807	7.62e-68	-	-	-	S	-	-	-	Enterocin A Immunity
KGCLDFHP_00809	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
KGCLDFHP_00810	2.16e-204	-	-	-	S	-	-	-	Phospholipase, patatin family
KGCLDFHP_00811	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
KGCLDFHP_00812	1.54e-164	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_00813	3.23e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGCLDFHP_00814	5.51e-206	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
KGCLDFHP_00815	8.44e-217	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
KGCLDFHP_00816	1.19e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
KGCLDFHP_00817	3.29e-191	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KGCLDFHP_00818	6.89e-181	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KGCLDFHP_00819	8.28e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
KGCLDFHP_00820	1.8e-78	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGCLDFHP_00821	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
KGCLDFHP_00822	1.98e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
KGCLDFHP_00823	4.72e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KGCLDFHP_00824	3.67e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KGCLDFHP_00825	1.61e-223	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
KGCLDFHP_00826	2.4e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
KGCLDFHP_00827	1.29e-70	-	-	-	S	-	-	-	Enterocin A Immunity
KGCLDFHP_00828	3.01e-180	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
KGCLDFHP_00829	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
KGCLDFHP_00830	6.34e-147	-	-	-	C	-	-	-	nitroreductase
KGCLDFHP_00831	6.35e-160	-	-	-	-	-	-	-	-
KGCLDFHP_00832	4.03e-301	yhdP	-	-	S	-	-	-	Transporter associated domain
KGCLDFHP_00833	2.11e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
KGCLDFHP_00834	2.31e-295	-	-	-	E	ko:K03294	-	ko00000	amino acid
KGCLDFHP_00835	1.34e-175	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KGCLDFHP_00836	5.69e-280	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
KGCLDFHP_00837	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGCLDFHP_00839	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
KGCLDFHP_00840	3.37e-221	-	-	-	K	-	-	-	LysR substrate binding domain
KGCLDFHP_00841	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KGCLDFHP_00842	2.31e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KGCLDFHP_00843	1.09e-171	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KGCLDFHP_00844	8.35e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
KGCLDFHP_00845	5.19e-111	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KGCLDFHP_00846	3.19e-239	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
KGCLDFHP_00847	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
KGCLDFHP_00848	7.19e-314	-	-	-	P	-	-	-	Major Facilitator Superfamily
KGCLDFHP_00849	3.48e-212	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
KGCLDFHP_00850	2.24e-239	-	-	-	M	-	-	-	Glycosyl transferase family 8
KGCLDFHP_00851	8.41e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
KGCLDFHP_00852	2.52e-199	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
KGCLDFHP_00853	1.4e-188	-	-	-	I	-	-	-	Acyl-transferase
KGCLDFHP_00856	1.03e-202	lysR5	-	-	K	-	-	-	LysR substrate binding domain
KGCLDFHP_00857	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
KGCLDFHP_00858	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
KGCLDFHP_00859	5.35e-123	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KGCLDFHP_00860	9.15e-240	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KGCLDFHP_00861	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KGCLDFHP_00862	0.0	potE	-	-	E	-	-	-	Amino Acid
KGCLDFHP_00863	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KGCLDFHP_00864	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
KGCLDFHP_00865	4.45e-157	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
KGCLDFHP_00866	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KGCLDFHP_00867	1.73e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KGCLDFHP_00868	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
KGCLDFHP_00869	6.8e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KGCLDFHP_00870	4.4e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KGCLDFHP_00871	8.8e-139	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KGCLDFHP_00873	5.39e-22	ansR	-	-	K	-	-	-	Transcriptional regulator
KGCLDFHP_00874	3.86e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
KGCLDFHP_00879	3.06e-39	-	-	-	-	-	-	-	-
KGCLDFHP_00883	4.87e-121	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
KGCLDFHP_00884	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
KGCLDFHP_00885	1.6e-222	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
KGCLDFHP_00886	4.06e-212	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KGCLDFHP_00887	4.75e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KGCLDFHP_00888	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KGCLDFHP_00889	1.32e-63	-	-	-	J	-	-	-	ribosomal protein
KGCLDFHP_00890	1.08e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
KGCLDFHP_00891	2.72e-281	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
KGCLDFHP_00892	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
KGCLDFHP_00893	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KGCLDFHP_00894	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KGCLDFHP_00895	8.99e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
KGCLDFHP_00896	3.37e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
KGCLDFHP_00897	5.91e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KGCLDFHP_00898	2.02e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KGCLDFHP_00899	4.12e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
KGCLDFHP_00900	8.74e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KGCLDFHP_00901	7.4e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
KGCLDFHP_00902	9.99e-246	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
KGCLDFHP_00903	3.9e-150	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
KGCLDFHP_00904	5.17e-293	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
KGCLDFHP_00905	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGCLDFHP_00906	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGCLDFHP_00907	4.85e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
KGCLDFHP_00908	1.7e-45	ynzC	-	-	S	-	-	-	UPF0291 protein
KGCLDFHP_00909	4.53e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KGCLDFHP_00910	1.77e-150	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
KGCLDFHP_00911	2.61e-96	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
KGCLDFHP_00912	2.63e-151	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KGCLDFHP_00913	2.61e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KGCLDFHP_00914	3.7e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
KGCLDFHP_00915	2.07e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KGCLDFHP_00916	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
KGCLDFHP_00917	1.99e-291	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KGCLDFHP_00918	3.48e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KGCLDFHP_00919	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KGCLDFHP_00920	4.07e-257	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KGCLDFHP_00921	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
KGCLDFHP_00922	1.29e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KGCLDFHP_00923	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGCLDFHP_00924	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGCLDFHP_00925	2.05e-39	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGCLDFHP_00926	1.06e-206	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGCLDFHP_00927	3.25e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KGCLDFHP_00928	8.34e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGCLDFHP_00929	9.96e-244	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGCLDFHP_00930	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KGCLDFHP_00931	1.23e-231	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KGCLDFHP_00932	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KGCLDFHP_00933	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
KGCLDFHP_00934	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
KGCLDFHP_00935	6.36e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
KGCLDFHP_00936	4.31e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
KGCLDFHP_00937	7.8e-156	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
KGCLDFHP_00938	6.45e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KGCLDFHP_00939	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
KGCLDFHP_00940	1.29e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
KGCLDFHP_00941	1.74e-307	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KGCLDFHP_00942	2.28e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KGCLDFHP_00943	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KGCLDFHP_00944	3.3e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KGCLDFHP_00945	3.6e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
KGCLDFHP_00946	7.04e-63	-	-	-	-	-	-	-	-
KGCLDFHP_00947	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
KGCLDFHP_00948	5.29e-199	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
KGCLDFHP_00949	6.21e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KGCLDFHP_00950	7.86e-46	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KGCLDFHP_00951	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KGCLDFHP_00952	3.69e-196	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KGCLDFHP_00953	1e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KGCLDFHP_00954	1.21e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
KGCLDFHP_00955	1.73e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KGCLDFHP_00956	1.57e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KGCLDFHP_00957	5.73e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
KGCLDFHP_00958	1.67e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
KGCLDFHP_00959	1.9e-79	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
KGCLDFHP_00960	4.65e-193	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KGCLDFHP_00961	2.8e-271	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
KGCLDFHP_00962	1.17e-17	-	-	-	-	-	-	-	-
KGCLDFHP_00963	2.18e-83	-	-	-	-	-	-	-	-
KGCLDFHP_00964	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
KGCLDFHP_00965	4.76e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
KGCLDFHP_00966	7.71e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
KGCLDFHP_00967	1.44e-72	-	-	-	-	-	-	-	-
KGCLDFHP_00968	3.72e-159	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KGCLDFHP_00969	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
KGCLDFHP_00970	8.29e-222	-	-	-	I	-	-	-	Carboxylesterase family
KGCLDFHP_00971	3e-75	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KGCLDFHP_00972	1.93e-81	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGCLDFHP_00973	2.8e-171	-	-	-	GK	-	-	-	ROK family
KGCLDFHP_00974	2.08e-13	-	-	-	GK	-	-	-	ROK family
KGCLDFHP_00975	1.67e-104	-	-	-	M	-	-	-	Sortase family
KGCLDFHP_00978	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KGCLDFHP_00979	2.03e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
KGCLDFHP_00980	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGCLDFHP_00981	3.24e-102	-	-	-	K	-	-	-	MerR HTH family regulatory protein
KGCLDFHP_00982	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
KGCLDFHP_00983	7.6e-121	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
KGCLDFHP_00984	8.08e-190	-	-	-	M	-	-	-	Glycosyl transferase family 2
KGCLDFHP_00985	8.04e-139	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
KGCLDFHP_00986	8.07e-91	-	-	-	-	-	-	-	-
KGCLDFHP_00987	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KGCLDFHP_00988	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
KGCLDFHP_00990	3.13e-179	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KGCLDFHP_00991	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
KGCLDFHP_00992	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KGCLDFHP_00993	3.85e-292	sptS	-	-	T	-	-	-	Histidine kinase
KGCLDFHP_00994	1.75e-150	dltr	-	-	K	-	-	-	response regulator
KGCLDFHP_00995	2.44e-148	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
KGCLDFHP_00996	1.84e-210	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
KGCLDFHP_00997	3.2e-91	-	-	-	O	-	-	-	OsmC-like protein
KGCLDFHP_00998	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KGCLDFHP_00999	6.12e-232	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01000	2.45e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
KGCLDFHP_01001	2.72e-208	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
KGCLDFHP_01002	1.21e-206	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
KGCLDFHP_01003	9.59e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
KGCLDFHP_01004	3.74e-115	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
KGCLDFHP_01005	2.58e-275	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KGCLDFHP_01007	1.04e-165	-	-	-	S	-	-	-	Putative ABC-transporter type IV
KGCLDFHP_01008	2.08e-77	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
KGCLDFHP_01009	4.51e-118	-	-	-	K	-	-	-	acetyltransferase
KGCLDFHP_01011	8.5e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
KGCLDFHP_01012	3.97e-311	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
KGCLDFHP_01013	1.69e-188	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
KGCLDFHP_01014	1.79e-100	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
KGCLDFHP_01015	1.65e-48	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
KGCLDFHP_01016	7.28e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KGCLDFHP_01017	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
KGCLDFHP_01018	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
KGCLDFHP_01019	0.0	-	-	-	S	-	-	-	TerB-C domain
KGCLDFHP_01020	9.59e-49	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
KGCLDFHP_01021	2.16e-106	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
KGCLDFHP_01022	2.91e-94	-	-	-	-	-	-	-	-
KGCLDFHP_01023	1.72e-267	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KGCLDFHP_01024	4.41e-224	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
KGCLDFHP_01025	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
KGCLDFHP_01026	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
KGCLDFHP_01027	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
KGCLDFHP_01028	1.39e-74	-	-	-	-	-	-	-	-
KGCLDFHP_01029	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KGCLDFHP_01030	1.45e-126	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
KGCLDFHP_01031	1.2e-190	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KGCLDFHP_01032	3.32e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
KGCLDFHP_01033	8.39e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
KGCLDFHP_01034	1.23e-228	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
KGCLDFHP_01035	5.77e-81	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
KGCLDFHP_01036	4.65e-194	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGCLDFHP_01037	2.01e-187	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
KGCLDFHP_01038	9.54e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
KGCLDFHP_01039	3.27e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
KGCLDFHP_01040	3.6e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGCLDFHP_01041	2.63e-73	ywnA	-	-	K	-	-	-	Transcriptional regulator
KGCLDFHP_01042	2.53e-123	-	-	-	-	-	-	-	-
KGCLDFHP_01043	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KGCLDFHP_01044	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
KGCLDFHP_01045	1.75e-259	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
KGCLDFHP_01046	7.55e-53	-	-	-	-	-	-	-	-
KGCLDFHP_01047	7.02e-105	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
KGCLDFHP_01048	4.04e-103	-	-	-	-	-	-	-	-
KGCLDFHP_01049	1.46e-42	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KGCLDFHP_01050	1.7e-101	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
KGCLDFHP_01051	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KGCLDFHP_01052	3.15e-232	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KGCLDFHP_01053	1.18e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KGCLDFHP_01054	1.91e-281	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
KGCLDFHP_01066	6.09e-81	-	-	-	-	-	-	-	-
KGCLDFHP_01085	3.49e-303	-	-	-	E	-	-	-	amino acid
KGCLDFHP_01086	1.98e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
KGCLDFHP_01087	2.21e-296	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
KGCLDFHP_01088	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
KGCLDFHP_01089	4.98e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
KGCLDFHP_01090	6.04e-220	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
KGCLDFHP_01091	1.23e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
KGCLDFHP_01092	1.83e-232	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KGCLDFHP_01094	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
KGCLDFHP_01095	1.36e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
KGCLDFHP_01096	1.35e-281	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
KGCLDFHP_01097	1.21e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KGCLDFHP_01098	4.63e-88	-	-	-	S	-	-	-	SdpI/YhfL protein family
KGCLDFHP_01099	1.89e-166	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
KGCLDFHP_01100	0.0	yclK	-	-	T	-	-	-	Histidine kinase
KGCLDFHP_01101	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
KGCLDFHP_01102	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
KGCLDFHP_01103	3.7e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KGCLDFHP_01104	6.12e-313	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGCLDFHP_01105	2.11e-53	-	-	-	-	-	-	-	-
KGCLDFHP_01106	3.82e-274	-	-	-	E	-	-	-	Major Facilitator Superfamily
KGCLDFHP_01108	2.13e-167	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KGCLDFHP_01109	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGCLDFHP_01110	0.0	yycH	-	-	S	-	-	-	YycH protein
KGCLDFHP_01111	1.49e-186	yycI	-	-	S	-	-	-	YycH protein
KGCLDFHP_01112	8.73e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
KGCLDFHP_01113	3.91e-235	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
KGCLDFHP_01114	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KGCLDFHP_01115	6.57e-144	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
KGCLDFHP_01116	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01117	1.32e-126	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
KGCLDFHP_01118	5.14e-216	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KGCLDFHP_01119	1.2e-208	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
KGCLDFHP_01120	2.67e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
KGCLDFHP_01121	4.27e-236	ysdE	-	-	P	-	-	-	Citrate transporter
KGCLDFHP_01122	7.84e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
KGCLDFHP_01123	1.14e-23	-	-	-	-	-	-	-	-
KGCLDFHP_01124	6.23e-151	-	-	-	-	-	-	-	-
KGCLDFHP_01126	2.59e-312	-	-	-	M	-	-	-	Glycosyl transferase
KGCLDFHP_01127	4.96e-270	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
KGCLDFHP_01128	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
KGCLDFHP_01129	1.65e-209	-	-	-	L	-	-	-	HNH nucleases
KGCLDFHP_01130	5.01e-61	-	-	-	-	-	-	-	-
KGCLDFHP_01131	4.83e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01132	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KGCLDFHP_01133	6.19e-149	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
KGCLDFHP_01134	4.1e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
KGCLDFHP_01135	2.41e-165	terC	-	-	P	-	-	-	Integral membrane protein TerC family
KGCLDFHP_01136	3.53e-112	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
KGCLDFHP_01137	6.37e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
KGCLDFHP_01138	1.28e-103	-	-	-	-	-	-	-	-
KGCLDFHP_01139	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KGCLDFHP_01140	5.18e-159	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
KGCLDFHP_01141	1.49e-224	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KGCLDFHP_01142	5.53e-180	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KGCLDFHP_01144	2.02e-220	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
KGCLDFHP_01145	5.52e-204	epsV	-	-	S	-	-	-	glycosyl transferase family 2
KGCLDFHP_01146	3.44e-161	-	-	-	S	-	-	-	Alpha/beta hydrolase family
KGCLDFHP_01147	2.78e-82	-	-	-	-	-	-	-	-
KGCLDFHP_01148	6.1e-230	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KGCLDFHP_01149	4.11e-308	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KGCLDFHP_01150	1.01e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGCLDFHP_01151	1.14e-161	-	-	-	-	-	-	-	-
KGCLDFHP_01152	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
KGCLDFHP_01153	3.19e-264	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KGCLDFHP_01154	2.79e-144	-	-	-	-	-	-	-	-
KGCLDFHP_01155	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KGCLDFHP_01156	3.33e-215	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
KGCLDFHP_01157	3.4e-157	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
KGCLDFHP_01158	6.18e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KGCLDFHP_01159	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
KGCLDFHP_01160	2.69e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
KGCLDFHP_01161	1.44e-276	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
KGCLDFHP_01162	5.34e-291	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KGCLDFHP_01163	9.66e-110	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KGCLDFHP_01164	8.1e-191	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
KGCLDFHP_01165	1.02e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
KGCLDFHP_01166	2.66e-88	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
KGCLDFHP_01167	5.08e-282	-	-	-	S	-	-	-	zinc-ribbon domain
KGCLDFHP_01168	1.56e-113	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
KGCLDFHP_01169	1.76e-128	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KGCLDFHP_01170	3.53e-169	-	-	-	K	-	-	-	UTRA domain
KGCLDFHP_01171	8.74e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KGCLDFHP_01172	6.03e-114	usp5	-	-	T	-	-	-	universal stress protein
KGCLDFHP_01174	1.16e-215	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
KGCLDFHP_01175	1.28e-181	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KGCLDFHP_01176	1.11e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGCLDFHP_01177	6.11e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGCLDFHP_01178	3.38e-109	-	-	-	-	-	-	-	-
KGCLDFHP_01179	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KGCLDFHP_01180	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
KGCLDFHP_01181	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
KGCLDFHP_01182	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
KGCLDFHP_01183	1.51e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KGCLDFHP_01184	6.48e-136	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KGCLDFHP_01185	1.8e-291	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
KGCLDFHP_01186	7.1e-291	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
KGCLDFHP_01187	2.95e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
KGCLDFHP_01188	0.0	-	-	-	D	-	-	-	transport
KGCLDFHP_01189	1.33e-174	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KGCLDFHP_01190	7.3e-216	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
KGCLDFHP_01191	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KGCLDFHP_01192	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KGCLDFHP_01193	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
KGCLDFHP_01194	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
KGCLDFHP_01195	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KGCLDFHP_01196	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KGCLDFHP_01197	4.33e-95	-	-	-	-	-	-	-	-
KGCLDFHP_01198	1.44e-176	-	-	-	-	-	-	-	-
KGCLDFHP_01199	3.41e-37	-	-	-	-	-	-	-	-
KGCLDFHP_01200	3.38e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
KGCLDFHP_01201	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KGCLDFHP_01202	0.0	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KGCLDFHP_01203	1.13e-184	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
KGCLDFHP_01204	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
KGCLDFHP_01205	1.01e-228	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KGCLDFHP_01206	8.33e-182	-	-	-	-	-	-	-	-
KGCLDFHP_01207	6.79e-184	-	-	-	-	-	-	-	-
KGCLDFHP_01208	2.4e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
KGCLDFHP_01209	2.23e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KGCLDFHP_01210	6.15e-62	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
KGCLDFHP_01211	4.38e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KGCLDFHP_01212	9.65e-95	-	-	-	S	-	-	-	GtrA-like protein
KGCLDFHP_01213	7.72e-228	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
KGCLDFHP_01214	6.21e-152	-	-	-	-	-	-	-	-
KGCLDFHP_01215	3.83e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
KGCLDFHP_01216	9.65e-218	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
KGCLDFHP_01217	1.59e-268	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KGCLDFHP_01218	3.45e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KGCLDFHP_01219	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
KGCLDFHP_01220	7.25e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KGCLDFHP_01222	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
KGCLDFHP_01223	5.93e-156	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KGCLDFHP_01224	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
KGCLDFHP_01225	1.06e-58	-	-	-	-	-	-	-	-
KGCLDFHP_01226	3.85e-98	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KGCLDFHP_01227	7.46e-97	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KGCLDFHP_01228	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KGCLDFHP_01229	2.35e-107	-	-	-	-	-	-	-	-
KGCLDFHP_01230	1.85e-316	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGCLDFHP_01231	6.9e-167	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
KGCLDFHP_01232	1.86e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
KGCLDFHP_01233	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KGCLDFHP_01234	2.81e-175	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
KGCLDFHP_01235	3.56e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
KGCLDFHP_01236	7.13e-56	-	-	-	-	-	-	-	-
KGCLDFHP_01237	3.44e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KGCLDFHP_01238	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGCLDFHP_01239	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KGCLDFHP_01240	1.2e-203	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
KGCLDFHP_01241	8.03e-151	-	-	-	-	-	-	-	-
KGCLDFHP_01243	1.03e-149	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
KGCLDFHP_01244	2.46e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KGCLDFHP_01245	9.68e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
KGCLDFHP_01246	3.58e-128	-	-	-	S	ko:K06872	-	ko00000	TPM domain
KGCLDFHP_01247	5.01e-233	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
KGCLDFHP_01248	0.0	-	-	-	M	-	-	-	family 8
KGCLDFHP_01249	0.0	-	-	-	M	-	-	-	family 8
KGCLDFHP_01250	5.21e-35	-	-	-	UW	-	-	-	Tetratricopeptide repeat
KGCLDFHP_01251	1.24e-58	-	-	-	UW	-	-	-	Tetratricopeptide repeat
KGCLDFHP_01252	1.24e-211	-	-	-	UW	-	-	-	Tetratricopeptide repeat
KGCLDFHP_01253	2.86e-08	-	-	-	UW	-	-	-	Tetratricopeptide repeat
KGCLDFHP_01254	3.26e-160	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
KGCLDFHP_01255	5.07e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
KGCLDFHP_01256	9.8e-259	-	-	-	S	-	-	-	membrane
KGCLDFHP_01257	9.62e-128	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
KGCLDFHP_01258	8.93e-191	-	-	-	GM	-	-	-	NmrA-like family
KGCLDFHP_01259	8.91e-142	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
KGCLDFHP_01260	1.29e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
KGCLDFHP_01261	4.17e-67	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
KGCLDFHP_01262	8e-197	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
KGCLDFHP_01263	2.09e-214	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KGCLDFHP_01264	4.71e-285	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
KGCLDFHP_01265	2.69e-185	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
KGCLDFHP_01266	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KGCLDFHP_01267	4.05e-135	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
KGCLDFHP_01268	4.62e-31	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
KGCLDFHP_01272	1.31e-193	-	-	-	EG	-	-	-	EamA-like transporter family
KGCLDFHP_01273	3.42e-88	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KGCLDFHP_01274	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
KGCLDFHP_01277	5.98e-212	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
KGCLDFHP_01278	1.21e-45	-	-	-	K	-	-	-	SIS domain
KGCLDFHP_01279	2.8e-48	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
KGCLDFHP_01281	6.19e-147	-	-	-	M	-	-	-	LysM domain protein
KGCLDFHP_01282	2.9e-165	-	-	-	M	-	-	-	LysM domain protein
KGCLDFHP_01283	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KGCLDFHP_01284	1.24e-312	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KGCLDFHP_01286	1.02e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KGCLDFHP_01287	1.21e-177	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
KGCLDFHP_01288	2.92e-37	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KGCLDFHP_01289	8.01e-66	-	-	-	-	-	-	-	-
KGCLDFHP_01291	6.66e-236	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KGCLDFHP_01292	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
KGCLDFHP_01293	6.13e-315	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KGCLDFHP_01294	4.17e-108	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KGCLDFHP_01295	1.5e-243	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KGCLDFHP_01296	2.89e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KGCLDFHP_01297	6.86e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KGCLDFHP_01298	3.16e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KGCLDFHP_01299	4.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KGCLDFHP_01300	1.75e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
KGCLDFHP_01301	5.75e-285	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
KGCLDFHP_01302	2.79e-293	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KGCLDFHP_01303	5.72e-104	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
KGCLDFHP_01304	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
KGCLDFHP_01305	1.02e-71	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KGCLDFHP_01306	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KGCLDFHP_01307	2.71e-180	-	-	-	H	-	-	-	Nodulation protein S (NodS)
KGCLDFHP_01308	0.000705	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
KGCLDFHP_01309	1.35e-240	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KGCLDFHP_01310	3.82e-181	-	-	-	S	-	-	-	PFAM Archaeal ATPase
KGCLDFHP_01311	7.49e-64	-	-	-	-	-	-	-	-
KGCLDFHP_01312	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
KGCLDFHP_01314	3.26e-74	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
KGCLDFHP_01315	3.11e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KGCLDFHP_01316	8.96e-101	-	-	-	S	-	-	-	Cupin domain
KGCLDFHP_01317	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
KGCLDFHP_01318	1.54e-91	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
KGCLDFHP_01319	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
KGCLDFHP_01320	9.5e-199	-	-	-	C	-	-	-	Aldo keto reductase
KGCLDFHP_01321	7.23e-25	lysR	-	-	K	-	-	-	Transcriptional regulator
KGCLDFHP_01322	8.78e-301	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
KGCLDFHP_01323	5.36e-218	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
KGCLDFHP_01324	6.22e-43	-	-	-	-	-	-	-	-
KGCLDFHP_01325	1.09e-141	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KGCLDFHP_01326	4.22e-211	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
KGCLDFHP_01327	3.74e-148	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
KGCLDFHP_01328	1.62e-149	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KGCLDFHP_01329	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KGCLDFHP_01330	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KGCLDFHP_01331	2.8e-229	-	-	-	K	-	-	-	Transcriptional regulator
KGCLDFHP_01332	2.02e-219	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
KGCLDFHP_01333	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
KGCLDFHP_01334	7.91e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KGCLDFHP_01335	1.28e-157	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KGCLDFHP_01336	9.84e-261	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
KGCLDFHP_01337	8.56e-129	lysR	-	-	K	-	-	-	Transcriptional regulator
KGCLDFHP_01338	1.18e-197	-	-	-	-	-	-	-	-
KGCLDFHP_01339	5.52e-209	-	-	-	S	-	-	-	EDD domain protein, DegV family
KGCLDFHP_01340	1.32e-84	-	-	-	-	-	-	-	-
KGCLDFHP_01341	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
KGCLDFHP_01342	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KGCLDFHP_01343	2.11e-248	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KGCLDFHP_01344	2.37e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KGCLDFHP_01345	7.17e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KGCLDFHP_01346	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
KGCLDFHP_01347	2.96e-72	-	-	-	-	-	-	-	-
KGCLDFHP_01348	1.38e-224	degV1	-	-	S	-	-	-	DegV family
KGCLDFHP_01349	1.41e-142	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
KGCLDFHP_01350	2.52e-304	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KGCLDFHP_01351	8.95e-273	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
KGCLDFHP_01352	2.77e-94	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KGCLDFHP_01353	2.37e-129	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
KGCLDFHP_01354	5.29e-148	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KGCLDFHP_01355	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
KGCLDFHP_01356	7.81e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KGCLDFHP_01357	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
KGCLDFHP_01358	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
KGCLDFHP_01359	2.66e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
KGCLDFHP_01360	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
KGCLDFHP_01361	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
KGCLDFHP_01362	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KGCLDFHP_01363	4.95e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
KGCLDFHP_01364	2.03e-224	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
KGCLDFHP_01365	4.33e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
KGCLDFHP_01366	1.35e-239	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KGCLDFHP_01367	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KGCLDFHP_01368	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KGCLDFHP_01369	5.2e-21	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KGCLDFHP_01370	7.11e-260	-	-	-	G	-	-	-	Transmembrane secretion effector
KGCLDFHP_01371	5.51e-200	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
KGCLDFHP_01372	5.97e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
KGCLDFHP_01373	5.83e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KGCLDFHP_01374	9.13e-202	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KGCLDFHP_01375	5.99e-109	-	-	-	S	-	-	-	ASCH
KGCLDFHP_01376	5.14e-157	-	-	-	F	-	-	-	Phosphorylase superfamily
KGCLDFHP_01377	3.57e-108	-	-	-	F	-	-	-	NUDIX domain
KGCLDFHP_01378	1.56e-188	-	-	-	M	-	-	-	Phosphotransferase enzyme family
KGCLDFHP_01379	1.77e-115	-	-	-	S	-	-	-	AAA domain
KGCLDFHP_01380	6.02e-208	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
KGCLDFHP_01381	1.07e-138	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
KGCLDFHP_01382	2.18e-112	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
KGCLDFHP_01383	4.16e-114	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KGCLDFHP_01384	3.03e-178	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
KGCLDFHP_01385	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KGCLDFHP_01386	1.8e-56	-	-	-	-	-	-	-	-
KGCLDFHP_01387	4.45e-157	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KGCLDFHP_01388	1.81e-78	-	-	-	-	-	-	-	-
KGCLDFHP_01389	2.64e-63	-	-	-	S	-	-	-	MazG-like family
KGCLDFHP_01390	8.11e-109	-	-	-	FG	-	-	-	HIT domain
KGCLDFHP_01391	2.34e-102	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGCLDFHP_01392	1.14e-100	-	-	-	-	-	-	-	-
KGCLDFHP_01393	6.92e-96	-	-	-	-	-	-	-	-
KGCLDFHP_01394	2.14e-138	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KGCLDFHP_01395	2.01e-57	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
KGCLDFHP_01396	8.69e-68	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
KGCLDFHP_01397	2.29e-70	-	-	-	-	-	-	-	-
KGCLDFHP_01398	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
KGCLDFHP_01399	5.8e-101	yfhC	-	-	C	-	-	-	nitroreductase
KGCLDFHP_01400	2.14e-260	-	-	-	P	-	-	-	Major Facilitator Superfamily
KGCLDFHP_01401	2.18e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KGCLDFHP_01402	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KGCLDFHP_01403	4.01e-229	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
KGCLDFHP_01404	1.21e-188	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
KGCLDFHP_01405	3.52e-15	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
KGCLDFHP_01406	9.45e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
KGCLDFHP_01407	7.38e-59	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
KGCLDFHP_01408	1.69e-13	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
KGCLDFHP_01409	6.31e-95	-	-	-	S	-	-	-	SnoaL-like domain
KGCLDFHP_01410	8.07e-148	-	-	-	C	-	-	-	nitroreductase
KGCLDFHP_01411	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KGCLDFHP_01412	9.91e-129	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KGCLDFHP_01413	4.44e-34	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KGCLDFHP_01414	8e-257	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KGCLDFHP_01415	1.34e-147	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01416	1.11e-138	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
KGCLDFHP_01417	2.07e-262	-	-	-	M	-	-	-	Glycosyl transferases group 1
KGCLDFHP_01418	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KGCLDFHP_01419	2.22e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
KGCLDFHP_01422	2.33e-301	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KGCLDFHP_01423	6.61e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KGCLDFHP_01424	7.38e-168	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KGCLDFHP_01425	9.81e-297	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KGCLDFHP_01426	1.38e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KGCLDFHP_01427	5.36e-102	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
KGCLDFHP_01428	7.23e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
KGCLDFHP_01429	5.36e-114	-	-	-	-	-	-	-	-
KGCLDFHP_01430	7.04e-121	-	-	-	-	-	-	-	-
KGCLDFHP_01431	4.11e-100	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
KGCLDFHP_01432	6.19e-86	-	-	-	S	-	-	-	Cupredoxin-like domain
KGCLDFHP_01433	3.13e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
KGCLDFHP_01434	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KGCLDFHP_01435	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KGCLDFHP_01436	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
KGCLDFHP_01437	2.33e-207	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KGCLDFHP_01438	0.0	-	-	-	E	-	-	-	Amino acid permease
KGCLDFHP_01439	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
KGCLDFHP_01440	3.8e-312	ynbB	-	-	P	-	-	-	aluminum resistance
KGCLDFHP_01441	1.46e-92	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGCLDFHP_01442	2.16e-295	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
KGCLDFHP_01443	1.09e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
KGCLDFHP_01444	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KGCLDFHP_01445	2.88e-267	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KGCLDFHP_01446	8.09e-206	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KGCLDFHP_01448	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KGCLDFHP_01449	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KGCLDFHP_01450	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KGCLDFHP_01451	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KGCLDFHP_01452	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KGCLDFHP_01453	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KGCLDFHP_01454	4.86e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KGCLDFHP_01455	8.89e-80	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KGCLDFHP_01456	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
KGCLDFHP_01457	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KGCLDFHP_01458	1.46e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KGCLDFHP_01459	7.88e-267	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KGCLDFHP_01460	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KGCLDFHP_01461	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KGCLDFHP_01462	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
KGCLDFHP_01463	5.89e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KGCLDFHP_01464	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KGCLDFHP_01465	1.42e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KGCLDFHP_01466	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
KGCLDFHP_01467	8.13e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KGCLDFHP_01468	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
KGCLDFHP_01469	1.27e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
KGCLDFHP_01470	1.39e-279	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
KGCLDFHP_01471	0.0	-	-	-	-	-	-	-	-
KGCLDFHP_01473	1.06e-314	steT	-	-	E	ko:K03294	-	ko00000	amino acid
KGCLDFHP_01475	1.41e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
KGCLDFHP_01476	4.23e-213	-	-	-	I	-	-	-	Acyltransferase
KGCLDFHP_01477	7.46e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
KGCLDFHP_01478	8.33e-185	-	-	-	K	-	-	-	Helix-turn-helix domain
KGCLDFHP_01479	7.74e-257	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Involved in molybdopterin and thiamine biosynthesis, family 2
KGCLDFHP_01480	7.91e-244	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KGCLDFHP_01481	8.09e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
KGCLDFHP_01482	4.52e-178	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
KGCLDFHP_01483	3.05e-198	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
KGCLDFHP_01484	1.07e-23	-	-	-	-	-	-	-	-
KGCLDFHP_01485	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KGCLDFHP_01486	3.37e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
KGCLDFHP_01487	0.0	fusA1	-	-	J	-	-	-	elongation factor G
KGCLDFHP_01488	5.01e-310	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KGCLDFHP_01489	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KGCLDFHP_01490	7.46e-199	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
KGCLDFHP_01491	7.92e-274	XK27_02480	-	-	EGP	-	-	-	Major facilitator Superfamily
KGCLDFHP_01492	6.07e-252	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
KGCLDFHP_01493	1.16e-212	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KGCLDFHP_01494	1.5e-20	-	-	-	S	-	-	-	CsbD-like
KGCLDFHP_01495	1.83e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
KGCLDFHP_01496	3.21e-207	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
KGCLDFHP_01497	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
KGCLDFHP_01498	3.74e-175	-	-	-	S	-	-	-	Alpha beta hydrolase
KGCLDFHP_01499	4.32e-37	-	-	-	-	-	-	-	-
KGCLDFHP_01500	9.61e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
KGCLDFHP_01501	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
KGCLDFHP_01502	1.95e-272	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KGCLDFHP_01503	8.92e-136	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
KGCLDFHP_01504	3.92e-246	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGCLDFHP_01505	0.0	-	-	-	S	-	-	-	domain, Protein
KGCLDFHP_01506	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KGCLDFHP_01507	0.0	-	-	-	M	-	-	-	domain protein
KGCLDFHP_01508	8.11e-152	-	-	-	M	-	-	-	domain protein
KGCLDFHP_01509	0.000673	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
KGCLDFHP_01514	2.13e-276	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KGCLDFHP_01515	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
KGCLDFHP_01516	1.19e-150	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
KGCLDFHP_01517	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
KGCLDFHP_01518	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
KGCLDFHP_01519	6.88e-279	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
KGCLDFHP_01520	4.14e-176	-	-	-	-	-	-	-	-
KGCLDFHP_01521	1.14e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KGCLDFHP_01522	1.13e-219	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KGCLDFHP_01523	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
KGCLDFHP_01524	3.79e-221	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
KGCLDFHP_01525	1.05e-60	-	-	-	-	-	-	-	-
KGCLDFHP_01526	1.67e-68	-	-	-	K	-	-	-	Sigma-54 interaction domain
KGCLDFHP_01527	0.0	-	-	-	K	-	-	-	Sigma-54 interaction domain
KGCLDFHP_01528	1.61e-71	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
KGCLDFHP_01529	7.29e-106	ptsB	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KGCLDFHP_01530	6.42e-176	ptsC	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
KGCLDFHP_01531	2.69e-190	ptsD	-	-	G	ko:K02796,ko:K19509	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
KGCLDFHP_01532	8.75e-146	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
KGCLDFHP_01533	3.3e-164	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
KGCLDFHP_01535	1.02e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
KGCLDFHP_01536	1.84e-162	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
KGCLDFHP_01537	3.85e-144	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
KGCLDFHP_01538	0.0	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
KGCLDFHP_01539	2.15e-109	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
KGCLDFHP_01540	5.09e-107	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
KGCLDFHP_01541	4.34e-281	-	-	-	P	-	-	-	Voltage gated chloride channel
KGCLDFHP_01542	2.01e-245	-	-	-	S	-	-	-	Bacteriocin helveticin-J
KGCLDFHP_01543	1.48e-128	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
KGCLDFHP_01544	5.06e-209	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
KGCLDFHP_01545	1.28e-181	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
KGCLDFHP_01546	9.83e-185	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KGCLDFHP_01547	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
KGCLDFHP_01548	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
KGCLDFHP_01549	5.22e-102	-	-	-	K	-	-	-	acetyltransferase
KGCLDFHP_01550	8.41e-260	-	-	-	S	-	-	-	PFAM Archaeal ATPase
KGCLDFHP_01551	4.87e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
KGCLDFHP_01552	1.43e-112	-	-	-	S	-	-	-	Protein of unknown function (DUF1440)
KGCLDFHP_01553	1.63e-192	-	-	-	S	-	-	-	hydrolase
KGCLDFHP_01554	1.78e-205	-	-	-	K	-	-	-	Transcriptional regulator
KGCLDFHP_01555	1.18e-308	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
KGCLDFHP_01556	5.79e-170	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
KGCLDFHP_01557	3.14e-94	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
KGCLDFHP_01558	1.17e-136	-	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
KGCLDFHP_01559	6.21e-151	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	CAT RNA binding domain
KGCLDFHP_01560	1.62e-71	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
KGCLDFHP_01561	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
KGCLDFHP_01562	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KGCLDFHP_01563	1.53e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
KGCLDFHP_01564	8.12e-144	-	-	-	I	-	-	-	Acid phosphatase homologues
KGCLDFHP_01565	0.0	-	-	-	E	-	-	-	Phospholipase B
KGCLDFHP_01566	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KGCLDFHP_01567	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
KGCLDFHP_01568	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
KGCLDFHP_01569	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KGCLDFHP_01570	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
KGCLDFHP_01571	1.18e-315	-	-	-	E	-	-	-	amino acid
KGCLDFHP_01572	1.67e-274	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
KGCLDFHP_01573	7.75e-40	-	-	-	-	-	-	-	-
KGCLDFHP_01574	6.45e-91	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KGCLDFHP_01575	2.04e-107	-	-	-	-	-	-	-	-
KGCLDFHP_01576	7.25e-265	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
KGCLDFHP_01578	3.97e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01579	4.05e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
KGCLDFHP_01580	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
KGCLDFHP_01581	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
KGCLDFHP_01582	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
KGCLDFHP_01583	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
KGCLDFHP_01584	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
KGCLDFHP_01585	0.0	-	-	-	E	-	-	-	Peptidase family C69
KGCLDFHP_01586	1.97e-277	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
KGCLDFHP_01587	5.71e-201	-	-	-	S	-	-	-	Alpha beta hydrolase
KGCLDFHP_01588	4.2e-87	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
KGCLDFHP_01589	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01590	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
KGCLDFHP_01591	6.33e-188	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGCLDFHP_01592	2.12e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01593	4.31e-191	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGCLDFHP_01594	1.75e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KGCLDFHP_01595	3.24e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KGCLDFHP_01596	1.68e-85	-	-	-	-	-	-	-	-
KGCLDFHP_01597	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KGCLDFHP_01598	7.08e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
KGCLDFHP_01599	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGCLDFHP_01600	8.35e-110	-	-	-	S	-	-	-	Putative adhesin
KGCLDFHP_01602	6.41e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
KGCLDFHP_01604	1.35e-20	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KGCLDFHP_01605	6.52e-103	-	-	-	-	-	-	-	-
KGCLDFHP_01606	7.58e-79	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
KGCLDFHP_01607	1.05e-53	-	-	-	-	-	-	-	-
KGCLDFHP_01608	2.22e-103	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
KGCLDFHP_01609	5.17e-176	-	-	-	S	-	-	-	Putative threonine/serine exporter
KGCLDFHP_01610	0.0	-	-	-	S	-	-	-	ABC transporter
KGCLDFHP_01611	5.46e-81	-	-	-	-	-	-	-	-
KGCLDFHP_01612	1.74e-53	-	-	-	-	-	-	-	-
KGCLDFHP_01613	5.55e-267	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KGCLDFHP_01614	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
KGCLDFHP_01615	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
KGCLDFHP_01616	1.03e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
KGCLDFHP_01617	1.56e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KGCLDFHP_01618	3.29e-203	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KGCLDFHP_01619	1.07e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
KGCLDFHP_01620	4.1e-178	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
KGCLDFHP_01621	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KGCLDFHP_01622	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
KGCLDFHP_01623	5.13e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KGCLDFHP_01624	1.38e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
KGCLDFHP_01625	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
KGCLDFHP_01626	1.58e-281	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KGCLDFHP_01627	2.08e-210	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01628	4.33e-183	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
KGCLDFHP_01629	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KGCLDFHP_01630	5.1e-264	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
KGCLDFHP_01631	2.39e-156	vanR	-	-	K	-	-	-	response regulator
KGCLDFHP_01632	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
KGCLDFHP_01633	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01634	5.43e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
KGCLDFHP_01635	1.89e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KGCLDFHP_01636	7.4e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
KGCLDFHP_01637	9.01e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KGCLDFHP_01638	3.52e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
KGCLDFHP_01639	7.73e-199	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KGCLDFHP_01640	7.13e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
KGCLDFHP_01641	3.16e-125	cvpA	-	-	S	-	-	-	Colicin V production protein
KGCLDFHP_01642	3.27e-228	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KGCLDFHP_01643	3.05e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KGCLDFHP_01644	3.15e-256	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
KGCLDFHP_01645	4.45e-128	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
KGCLDFHP_01646	3.69e-124	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
KGCLDFHP_01647	4e-140	-	-	-	K	-	-	-	WHG domain
KGCLDFHP_01648	1.36e-50	-	-	-	-	-	-	-	-
KGCLDFHP_01649	4.48e-257	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KGCLDFHP_01650	4.44e-66	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KGCLDFHP_01651	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KGCLDFHP_01652	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGCLDFHP_01653	9.86e-201	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
KGCLDFHP_01654	3.39e-151	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01655	1.44e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KGCLDFHP_01656	1.91e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGCLDFHP_01657	4.06e-145	-	-	-	G	-	-	-	phosphoglycerate mutase
KGCLDFHP_01658	5.95e-147	-	-	-	G	-	-	-	Phosphoglycerate mutase family
KGCLDFHP_01659	6.89e-180	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
KGCLDFHP_01660	5.24e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
KGCLDFHP_01661	9.32e-67	-	-	-	-	-	-	-	-
KGCLDFHP_01662	2.6e-165	-	-	-	-	-	-	-	-
KGCLDFHP_01663	2.16e-208	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KGCLDFHP_01664	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGCLDFHP_01665	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
KGCLDFHP_01666	6.15e-185	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
KGCLDFHP_01667	5.67e-196	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KGCLDFHP_01668	7.26e-200	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
KGCLDFHP_01669	1.06e-91	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
KGCLDFHP_01670	1.57e-200	-	-	-	-	-	-	-	-
KGCLDFHP_01671	3.53e-276	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
KGCLDFHP_01672	2.06e-161	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
KGCLDFHP_01673	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
KGCLDFHP_01674	7.28e-117	ymdB	-	-	S	-	-	-	Macro domain protein
KGCLDFHP_01675	1.26e-241	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KGCLDFHP_01676	2.2e-12	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KGCLDFHP_01677	1.98e-203	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KGCLDFHP_01678	6.45e-47	-	-	-	-	-	-	-	-
KGCLDFHP_01679	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGCLDFHP_01680	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
KGCLDFHP_01681	1.57e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
KGCLDFHP_01682	4.68e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KGCLDFHP_01683	8.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
KGCLDFHP_01684	3.43e-169	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
KGCLDFHP_01685	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
KGCLDFHP_01686	2.61e-205	-	-	-	EG	-	-	-	EamA-like transporter family
KGCLDFHP_01687	7.01e-244	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
KGCLDFHP_01688	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KGCLDFHP_01689	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
KGCLDFHP_01690	1.02e-34	-	-	-	-	-	-	-	-
KGCLDFHP_01691	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
KGCLDFHP_01692	2.17e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
KGCLDFHP_01693	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KGCLDFHP_01694	5.48e-201	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
KGCLDFHP_01695	9.44e-99	-	-	-	-	-	-	-	-
KGCLDFHP_01696	1.37e-115	-	-	-	-	-	-	-	-
KGCLDFHP_01697	1.37e-146	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
KGCLDFHP_01698	4.46e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
KGCLDFHP_01699	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KGCLDFHP_01700	4.65e-277	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
KGCLDFHP_01701	4.68e-280	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
KGCLDFHP_01702	6.12e-278	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
KGCLDFHP_01703	1.56e-229	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
KGCLDFHP_01705	5.24e-190	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KGCLDFHP_01706	7.77e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KGCLDFHP_01707	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
KGCLDFHP_01708	2.54e-215	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KGCLDFHP_01709	1.18e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
KGCLDFHP_01710	2.09e-76	yqhL	-	-	P	-	-	-	Rhodanese-like protein
KGCLDFHP_01711	3.31e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
KGCLDFHP_01712	2.67e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
KGCLDFHP_01713	6.82e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KGCLDFHP_01714	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KGCLDFHP_01715	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KGCLDFHP_01716	0.0	-	-	-	S	-	-	-	membrane
KGCLDFHP_01717	5.34e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KGCLDFHP_01718	5.27e-260	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KGCLDFHP_01719	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KGCLDFHP_01720	9.43e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KGCLDFHP_01721	1.19e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KGCLDFHP_01722	3.14e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KGCLDFHP_01723	8.53e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
KGCLDFHP_01724	9.51e-217	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KGCLDFHP_01725	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGCLDFHP_01726	1.89e-169	csrR	-	-	K	-	-	-	response regulator
KGCLDFHP_01727	1.28e-121	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
KGCLDFHP_01728	4.15e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
KGCLDFHP_01729	4.36e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KGCLDFHP_01730	8.88e-144	yqeK	-	-	H	-	-	-	Hydrolase, HD family
KGCLDFHP_01731	9.54e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KGCLDFHP_01732	1.37e-269	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
KGCLDFHP_01733	1.29e-112	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
KGCLDFHP_01734	7.56e-242	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KGCLDFHP_01735	1.23e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KGCLDFHP_01736	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
KGCLDFHP_01737	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KGCLDFHP_01738	3.73e-303	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KGCLDFHP_01739	1.43e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
KGCLDFHP_01740	5.61e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
KGCLDFHP_01741	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KGCLDFHP_01742	1.05e-199	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
KGCLDFHP_01743	8.86e-303	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
KGCLDFHP_01744	1.2e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KGCLDFHP_01745	3.74e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KGCLDFHP_01746	8.18e-206	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KGCLDFHP_01747	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KGCLDFHP_01748	2.58e-65	-	-	-	-	-	-	-	-
KGCLDFHP_01749	4.16e-195	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
KGCLDFHP_01750	4.1e-190	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
KGCLDFHP_01751	9.23e-124	levB	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KGCLDFHP_01752	8.55e-99	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
KGCLDFHP_01753	9.32e-225	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
KGCLDFHP_01754	1.89e-293	degS	2.7.13.3	-	F	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
KGCLDFHP_01755	1.19e-154	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
KGCLDFHP_01756	3.01e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGCLDFHP_01757	5.24e-169	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KGCLDFHP_01758	1.96e-164	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
KGCLDFHP_01759	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
KGCLDFHP_01760	3.58e-156	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KGCLDFHP_01761	4.72e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
KGCLDFHP_01762	1.19e-84	-	-	-	-	-	-	-	-
KGCLDFHP_01763	1.77e-162	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KGCLDFHP_01764	8.54e-288	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KGCLDFHP_01765	1.38e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGCLDFHP_01766	2.38e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
KGCLDFHP_01767	2.56e-85	-	-	-	-	-	-	-	-
KGCLDFHP_01768	1.2e-47	-	-	-	S	-	-	-	YtxH-like protein
KGCLDFHP_01769	3.04e-203	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KGCLDFHP_01770	1.25e-236	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
KGCLDFHP_01771	0.0	yhaN	-	-	L	-	-	-	AAA domain
KGCLDFHP_01772	2.52e-282	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
KGCLDFHP_01773	1.57e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
KGCLDFHP_01774	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KGCLDFHP_01775	3.74e-205	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
KGCLDFHP_01777	2.07e-32	-	-	-	UW	-	-	-	Tetratricopeptide repeat
KGCLDFHP_01778	3.35e-213	-	-	-	S	-	-	-	glycosyl transferase family 2
KGCLDFHP_01779	5.61e-253	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
KGCLDFHP_01780	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KGCLDFHP_01781	1.63e-237	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KGCLDFHP_01782	3.82e-133	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
KGCLDFHP_01783	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KGCLDFHP_01784	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KGCLDFHP_01785	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KGCLDFHP_01786	5.57e-104	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KGCLDFHP_01787	1.28e-176	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KGCLDFHP_01788	5.1e-114	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
KGCLDFHP_01789	5.9e-46	-	-	-	-	-	-	-	-
KGCLDFHP_01790	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
KGCLDFHP_01791	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KGCLDFHP_01792	5.84e-292	-	-	-	G	-	-	-	Major Facilitator Superfamily
KGCLDFHP_01793	2.96e-243	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KGCLDFHP_01794	1.48e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KGCLDFHP_01795	8.06e-17	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KGCLDFHP_01796	5.22e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
KGCLDFHP_01797	1.89e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KGCLDFHP_01798	2.48e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KGCLDFHP_01799	3.38e-140	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
KGCLDFHP_01800	3.7e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
KGCLDFHP_01801	5.46e-186	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KGCLDFHP_01802	1.78e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KGCLDFHP_01803	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KGCLDFHP_01804	6.33e-181	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
KGCLDFHP_01805	3.25e-44	-	-	-	-	-	-	-	-
KGCLDFHP_01806	6.45e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
KGCLDFHP_01807	1.65e-31	-	-	-	-	-	-	-	-
KGCLDFHP_01808	1.64e-186	-	-	-	-	-	-	-	-
KGCLDFHP_01809	1.63e-64	-	-	-	S	-	-	-	Protein conserved in bacteria
KGCLDFHP_01810	2.48e-111	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KGCLDFHP_01811	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KGCLDFHP_01812	2.22e-67	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KGCLDFHP_01813	2.53e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KGCLDFHP_01814	1.24e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
KGCLDFHP_01815	1.45e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KGCLDFHP_01816	1.24e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
KGCLDFHP_01817	1.9e-195	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KGCLDFHP_01818	3.33e-78	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
KGCLDFHP_01819	1.98e-197	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KGCLDFHP_01820	2.14e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
KGCLDFHP_01821	2.99e-102	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
KGCLDFHP_01822	2.9e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
KGCLDFHP_01823	7.45e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
KGCLDFHP_01824	4.98e-250	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KGCLDFHP_01825	5.23e-271	-	-	-	D	-	-	-	nuclear chromosome segregation
KGCLDFHP_01826	1.58e-91	-	-	-	-	-	-	-	-
KGCLDFHP_01827	2.34e-148	-	-	-	-	-	-	-	-
KGCLDFHP_01828	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KGCLDFHP_01829	8.15e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KGCLDFHP_01830	9.69e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KGCLDFHP_01831	8.98e-311	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KGCLDFHP_01832	1.57e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGCLDFHP_01833	1.33e-101	-	-	-	-	-	-	-	-
KGCLDFHP_01834	6.1e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGCLDFHP_01835	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
KGCLDFHP_01836	1.45e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state