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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
CIGDHHLC_00001	5.55e-301	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CIGDHHLC_00002	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CIGDHHLC_00003	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
CIGDHHLC_00004	1.85e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CIGDHHLC_00005	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
CIGDHHLC_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIGDHHLC_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIGDHHLC_00008	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
CIGDHHLC_00011	5.89e-230	yaaC	-	-	S	-	-	-	YaaC-like Protein
CIGDHHLC_00012	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CIGDHHLC_00013	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CIGDHHLC_00014	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CIGDHHLC_00015	5.55e-137	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CIGDHHLC_00016	4.64e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CIGDHHLC_00018	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
CIGDHHLC_00019	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
CIGDHHLC_00020	7.55e-271	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
CIGDHHLC_00021	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
CIGDHHLC_00022	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CIGDHHLC_00023	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIGDHHLC_00024	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CIGDHHLC_00025	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CIGDHHLC_00026	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
CIGDHHLC_00027	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
CIGDHHLC_00028	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
CIGDHHLC_00031	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
CIGDHHLC_00032	6.08e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CIGDHHLC_00033	1.19e-258	yaaN	-	-	P	-	-	-	Belongs to the TelA family
CIGDHHLC_00034	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
CIGDHHLC_00035	4.67e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CIGDHHLC_00036	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_00037	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
CIGDHHLC_00038	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CIGDHHLC_00039	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
CIGDHHLC_00040	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
CIGDHHLC_00041	4.66e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
CIGDHHLC_00042	2.84e-63	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
CIGDHHLC_00043	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CIGDHHLC_00044	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
CIGDHHLC_00045	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIGDHHLC_00046	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
CIGDHHLC_00047	1.18e-277	yabE	-	-	T	-	-	-	protein conserved in bacteria
CIGDHHLC_00048	2.46e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CIGDHHLC_00049	1.24e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CIGDHHLC_00050	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_00052	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
CIGDHHLC_00053	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_00054	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
CIGDHHLC_00055	9.53e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CIGDHHLC_00056	3.82e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
CIGDHHLC_00057	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
CIGDHHLC_00058	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
CIGDHHLC_00059	1.49e-308	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CIGDHHLC_00060	7.08e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIGDHHLC_00061	1.69e-135	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CIGDHHLC_00062	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CIGDHHLC_00063	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
CIGDHHLC_00064	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CIGDHHLC_00065	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
CIGDHHLC_00066	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CIGDHHLC_00067	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
CIGDHHLC_00068	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CIGDHHLC_00069	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
CIGDHHLC_00070	2.58e-138	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
CIGDHHLC_00071	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
CIGDHHLC_00072	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
CIGDHHLC_00075	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
CIGDHHLC_00076	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
CIGDHHLC_00077	1.61e-220	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
CIGDHHLC_00078	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CIGDHHLC_00079	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
CIGDHHLC_00080	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIGDHHLC_00081	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CIGDHHLC_00082	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CIGDHHLC_00083	2.41e-204	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
CIGDHHLC_00084	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
CIGDHHLC_00086	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_00087	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CIGDHHLC_00088	2.44e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
CIGDHHLC_00089	2.09e-212	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
CIGDHHLC_00090	5.28e-202	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CIGDHHLC_00091	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CIGDHHLC_00092	1.31e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CIGDHHLC_00093	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
CIGDHHLC_00094	3.75e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CIGDHHLC_00095	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
CIGDHHLC_00096	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
CIGDHHLC_00106	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
CIGDHHLC_00107	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
CIGDHHLC_00108	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
CIGDHHLC_00109	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
CIGDHHLC_00110	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
CIGDHHLC_00111	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CIGDHHLC_00112	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CIGDHHLC_00113	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
CIGDHHLC_00114	3.02e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CIGDHHLC_00115	1.82e-112	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CIGDHHLC_00116	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIGDHHLC_00117	5.46e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
CIGDHHLC_00118	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CIGDHHLC_00119	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CIGDHHLC_00120	8.65e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIGDHHLC_00121	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
CIGDHHLC_00122	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
CIGDHHLC_00123	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CIGDHHLC_00124	1.19e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
CIGDHHLC_00125	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CIGDHHLC_00126	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CIGDHHLC_00127	1.64e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CIGDHHLC_00128	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CIGDHHLC_00129	2.43e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
CIGDHHLC_00130	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIGDHHLC_00131	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIGDHHLC_00132	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
CIGDHHLC_00133	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CIGDHHLC_00134	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CIGDHHLC_00135	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CIGDHHLC_00136	1.36e-285	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CIGDHHLC_00137	1.83e-230	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
CIGDHHLC_00138	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
CIGDHHLC_00139	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CIGDHHLC_00140	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
CIGDHHLC_00141	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CIGDHHLC_00142	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CIGDHHLC_00143	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CIGDHHLC_00144	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CIGDHHLC_00145	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CIGDHHLC_00146	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CIGDHHLC_00147	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
CIGDHHLC_00148	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CIGDHHLC_00149	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CIGDHHLC_00150	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CIGDHHLC_00151	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CIGDHHLC_00152	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIGDHHLC_00153	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CIGDHHLC_00154	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CIGDHHLC_00155	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CIGDHHLC_00156	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CIGDHHLC_00157	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
CIGDHHLC_00158	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
CIGDHHLC_00159	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CIGDHHLC_00160	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CIGDHHLC_00161	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
CIGDHHLC_00162	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CIGDHHLC_00163	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
CIGDHHLC_00164	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CIGDHHLC_00165	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CIGDHHLC_00166	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIGDHHLC_00167	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
CIGDHHLC_00168	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIGDHHLC_00169	2.69e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIGDHHLC_00170	4.39e-175	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIGDHHLC_00171	2.51e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CIGDHHLC_00172	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CIGDHHLC_00173	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
CIGDHHLC_00174	1.45e-184	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
CIGDHHLC_00175	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
CIGDHHLC_00176	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
CIGDHHLC_00177	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CIGDHHLC_00178	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
CIGDHHLC_00179	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
CIGDHHLC_00180	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
CIGDHHLC_00181	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
CIGDHHLC_00188	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
CIGDHHLC_00189	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
CIGDHHLC_00190	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
CIGDHHLC_00192	5.36e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
CIGDHHLC_00193	7.76e-182	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
CIGDHHLC_00194	1.43e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_00195	5.81e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_00196	2.54e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
CIGDHHLC_00197	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
CIGDHHLC_00198	6.63e-270	ybbC	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_00199	8.03e-21	ybbC	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_00200	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
CIGDHHLC_00201	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
CIGDHHLC_00202	2.09e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_00203	3.14e-193	ybbH	-	-	K	-	-	-	transcriptional
CIGDHHLC_00204	1.64e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CIGDHHLC_00205	8.99e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
CIGDHHLC_00206	9.88e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
CIGDHHLC_00212	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIGDHHLC_00213	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
CIGDHHLC_00214	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CIGDHHLC_00215	3.55e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_00216	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CIGDHHLC_00217	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CIGDHHLC_00220	0.0	papA4	-	-	Q	ko:K12240	ko01053,map01053	ko00000,ko00001,ko01008	synthase
CIGDHHLC_00221	0.0	-	-	-	IQ	ko:K15641,ko:K16398,ko:K16417,ko:K20788	ko01052,map01052	ko00000,ko00001,ko01008	PKS_KR
CIGDHHLC_00222	1.42e-56	-	-	-	S	-	-	-	MepB protein
CIGDHHLC_00223	8.33e-58	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
CIGDHHLC_00224	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CIGDHHLC_00225	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
CIGDHHLC_00226	1.34e-120	ybcF	-	-	P	-	-	-	carbonic anhydrase
CIGDHHLC_00227	5.59e-64	-	-	-	-	-	-	-	-
CIGDHHLC_00228	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
CIGDHHLC_00229	1.55e-65	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
CIGDHHLC_00230	1.89e-70	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
CIGDHHLC_00231	2.05e-131	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
CIGDHHLC_00233	1.96e-178	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
CIGDHHLC_00234	1.49e-192	ybdN	-	-	-	-	-	-	-
CIGDHHLC_00235	4.65e-276	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
CIGDHHLC_00236	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
CIGDHHLC_00237	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_00239	2.23e-50	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
CIGDHHLC_00240	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
CIGDHHLC_00241	1.24e-191	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
CIGDHHLC_00242	2.99e-311	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
CIGDHHLC_00243	1.28e-37	ybyB	-	-	-	-	-	-	-
CIGDHHLC_00244	0.0	ybeC	-	-	E	-	-	-	amino acid
CIGDHHLC_00245	2.09e-212	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
CIGDHHLC_00246	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
CIGDHHLC_00247	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
CIGDHHLC_00248	8.65e-202	ybfA	-	-	K	-	-	-	FR47-like protein
CIGDHHLC_00249	5.4e-184	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_00250	6.21e-57	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_00253	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
CIGDHHLC_00254	5.01e-133	ybfH	-	-	EG	-	-	-	EamA-like transporter family
CIGDHHLC_00255	2.88e-185	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
CIGDHHLC_00256	3.63e-43	-	-	-	K	-	-	-	sigma factor activity
CIGDHHLC_00257	2.73e-28	xhlB	-	-	S	-	-	-	SPP1 phage holin
CIGDHHLC_00258	4.74e-207	-	-	GH19	M	ko:K03791	-	ko00000	Lysin motif
CIGDHHLC_00259	2.61e-73	-	-	-	-	-	-	-	-
CIGDHHLC_00260	1.54e-269	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CIGDHHLC_00261	3.97e-227	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
CIGDHHLC_00263	1.31e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase family
CIGDHHLC_00264	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIGDHHLC_00265	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
CIGDHHLC_00266	6.15e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
CIGDHHLC_00267	2.25e-59	ybfN	-	-	-	-	-	-	-
CIGDHHLC_00268	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
CIGDHHLC_00269	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_00270	2.35e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
CIGDHHLC_00271	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CIGDHHLC_00272	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_00273	4.29e-174	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CIGDHHLC_00274	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
CIGDHHLC_00276	3.29e-259	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
CIGDHHLC_00277	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
CIGDHHLC_00278	1.83e-233	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
CIGDHHLC_00279	2.77e-37	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
CIGDHHLC_00280	2.97e-270	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
CIGDHHLC_00281	4.35e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
CIGDHHLC_00282	5.88e-293	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_00283	5.76e-216	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
CIGDHHLC_00284	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
CIGDHHLC_00285	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CIGDHHLC_00286	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_00287	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
CIGDHHLC_00288	7.68e-160	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
CIGDHHLC_00289	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
CIGDHHLC_00290	3.51e-222	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
CIGDHHLC_00291	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
CIGDHHLC_00292	2.85e-215	eamA1	-	-	EG	-	-	-	spore germination
CIGDHHLC_00293	5.28e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_00294	4.37e-214	ycbM	-	-	T	-	-	-	Histidine kinase
CIGDHHLC_00295	5.55e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_00296	1.73e-149	-	-	-	S	-	-	-	ABC-2 family transporter protein
CIGDHHLC_00297	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
CIGDHHLC_00298	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
CIGDHHLC_00299	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_00300	3.83e-174	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
CIGDHHLC_00301	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
CIGDHHLC_00302	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CIGDHHLC_00303	3.61e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CIGDHHLC_00304	4.68e-152	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CIGDHHLC_00305	1.39e-258	ycbU	-	-	E	-	-	-	Selenocysteine lyase
CIGDHHLC_00306	1.45e-301	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
CIGDHHLC_00307	7.64e-131	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
CIGDHHLC_00308	8.02e-256	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CIGDHHLC_00309	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CIGDHHLC_00310	4.32e-78	-	-	-	S	-	-	-	RDD family
CIGDHHLC_00311	7.13e-255	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
CIGDHHLC_00312	6.18e-213	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
CIGDHHLC_00313	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
CIGDHHLC_00314	5.41e-171	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIGDHHLC_00315	9.75e-258	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
CIGDHHLC_00316	2.9e-28	yccK	-	-	C	-	-	-	Aldo keto reductase
CIGDHHLC_00317	4.58e-68	yccK	-	-	C	-	-	-	Aldo keto reductase
CIGDHHLC_00318	6.38e-229	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
CIGDHHLC_00319	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIGDHHLC_00320	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIGDHHLC_00321	1.53e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
CIGDHHLC_00322	1.65e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
CIGDHHLC_00323	7.67e-177	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
CIGDHHLC_00324	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
CIGDHHLC_00325	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CIGDHHLC_00326	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CIGDHHLC_00327	1.88e-172	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CIGDHHLC_00328	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_00330	6.56e-107	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIGDHHLC_00331	1.07e-81	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIGDHHLC_00332	2.53e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
CIGDHHLC_00333	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
CIGDHHLC_00334	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
CIGDHHLC_00335	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
CIGDHHLC_00336	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
CIGDHHLC_00337	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
CIGDHHLC_00338	2.59e-276	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
CIGDHHLC_00339	1.72e-255	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
CIGDHHLC_00340	8.04e-181	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
CIGDHHLC_00341	1.9e-41	-	-	-	S	-	-	-	DNA sulphur modification protein DndE
CIGDHHLC_00342	3.14e-187	-	-	-	EL	ko:K19171	-	ko00000,ko02048	AAA domain
CIGDHHLC_00343	8.5e-272	-	-	-	EH	ko:K19170	-	ko00000,ko02048	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes
CIGDHHLC_00344	2.86e-193	-	-	-	S	ko:K19169	-	ko00000,ko02048	DNA-sulfur modification-associated
CIGDHHLC_00345	3.83e-131	-	-	-	V	ko:K19173	-	ko00000,ko02048	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CIGDHHLC_00346	2.19e-86	-	-	-	-	ko:K19174	-	ko00000,ko02048	-
CIGDHHLC_00347	0.0	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
CIGDHHLC_00348	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CIGDHHLC_00349	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
CIGDHHLC_00350	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
CIGDHHLC_00351	4.73e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
CIGDHHLC_00352	4.44e-273	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
CIGDHHLC_00353	0.0	ycgA	-	-	S	-	-	-	Membrane
CIGDHHLC_00354	2.72e-105	ycgB	-	-	-	-	-	-	-
CIGDHHLC_00355	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
CIGDHHLC_00356	1.31e-121	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
CIGDHHLC_00357	2.93e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CIGDHHLC_00358	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
CIGDHHLC_00359	3.07e-194	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
CIGDHHLC_00360	4.4e-134	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
CIGDHHLC_00361	2.67e-154	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
CIGDHHLC_00362	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
CIGDHHLC_00363	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CIGDHHLC_00364	1.31e-140	tmrB	-	-	S	-	-	-	AAA domain
CIGDHHLC_00365	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CIGDHHLC_00366	1.29e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
CIGDHHLC_00367	5.64e-228	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
CIGDHHLC_00368	1.1e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
CIGDHHLC_00369	3.69e-185	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
CIGDHHLC_00370	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
CIGDHHLC_00371	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
CIGDHHLC_00372	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CIGDHHLC_00373	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
CIGDHHLC_00374	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
CIGDHHLC_00375	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
CIGDHHLC_00376	3.3e-200	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
CIGDHHLC_00377	8.53e-245	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
CIGDHHLC_00378	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
CIGDHHLC_00379	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
CIGDHHLC_00380	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CIGDHHLC_00381	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CIGDHHLC_00382	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
CIGDHHLC_00383	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
CIGDHHLC_00384	2.21e-150	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
CIGDHHLC_00385	2.12e-87	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CIGDHHLC_00386	2.72e-141	yciC	-	-	S	-	-	-	GTPases (G3E family)
CIGDHHLC_00387	2.26e-123	yciC	-	-	S	-	-	-	GTPases (G3E family)
CIGDHHLC_00388	3.35e-146	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
CIGDHHLC_00389	1.03e-184	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
CIGDHHLC_00392	4.34e-39	yckC	-	-	S	-	-	-	membrane
CIGDHHLC_00393	1.38e-66	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
CIGDHHLC_00394	1.06e-57	-	-	-	K	-	-	-	MarR family
CIGDHHLC_00395	2.49e-27	-	-	-	-	-	-	-	-
CIGDHHLC_00396	2.13e-113	-	-	-	S	-	-	-	AAA domain
CIGDHHLC_00397	8.9e-22	-	-	-	S	-	-	-	AAA domain
CIGDHHLC_00398	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CIGDHHLC_00399	3.36e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
CIGDHHLC_00400	7.94e-100	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
CIGDHHLC_00401	3.11e-73	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
CIGDHHLC_00402	9.46e-163	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
CIGDHHLC_00403	3.24e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
CIGDHHLC_00404	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
CIGDHHLC_00405	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
CIGDHHLC_00406	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIGDHHLC_00407	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIGDHHLC_00408	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
CIGDHHLC_00409	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
CIGDHHLC_00410	4.92e-285	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIGDHHLC_00411	1.48e-122	-	-	-	S	-	-	-	YcxB-like protein
CIGDHHLC_00412	1.17e-198	ycxC	-	-	EG	-	-	-	EamA-like transporter family
CIGDHHLC_00413	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
CIGDHHLC_00414	8.24e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
CIGDHHLC_00415	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
CIGDHHLC_00416	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
CIGDHHLC_00417	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
CIGDHHLC_00418	4.3e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
CIGDHHLC_00419	1.25e-207	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
CIGDHHLC_00420	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CIGDHHLC_00421	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
CIGDHHLC_00422	4.02e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
CIGDHHLC_00423	6.45e-55	yclD	-	-	-	-	-	-	-
CIGDHHLC_00424	6.42e-201	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
CIGDHHLC_00425	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
CIGDHHLC_00426	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
CIGDHHLC_00427	1.62e-242	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_00429	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
CIGDHHLC_00430	1.22e-289	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
CIGDHHLC_00431	5.28e-244	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
CIGDHHLC_00432	1.33e-152	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CIGDHHLC_00433	5.23e-274	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
CIGDHHLC_00434	2.23e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_00435	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
CIGDHHLC_00436	7.71e-98	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
CIGDHHLC_00438	7.93e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
CIGDHHLC_00439	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
CIGDHHLC_00440	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_00441	3.16e-209	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_00442	2.29e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_00443	4.69e-212	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
CIGDHHLC_00444	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
CIGDHHLC_00445	5.87e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_00446	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
CIGDHHLC_00447	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
CIGDHHLC_00448	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CIGDHHLC_00449	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CIGDHHLC_00450	3.26e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CIGDHHLC_00451	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CIGDHHLC_00452	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
CIGDHHLC_00453	3.27e-184	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_00454	1.34e-132	ycnI	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_00455	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
CIGDHHLC_00456	2.03e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
CIGDHHLC_00457	1.34e-74	-	-	-	-	-	-	-	-
CIGDHHLC_00458	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
CIGDHHLC_00459	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
CIGDHHLC_00460	1.41e-264	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
CIGDHHLC_00461	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
CIGDHHLC_00463	1.25e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CIGDHHLC_00464	1.32e-24	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
CIGDHHLC_00465	2.68e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
CIGDHHLC_00466	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_00467	4.63e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_00468	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
CIGDHHLC_00469	1.1e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
CIGDHHLC_00470	1.87e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
CIGDHHLC_00471	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
CIGDHHLC_00472	9.77e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
CIGDHHLC_00473	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
CIGDHHLC_00474	1.55e-170	kipR	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_00475	5.94e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
CIGDHHLC_00477	8.97e-65	yczJ	-	-	S	-	-	-	biosynthesis
CIGDHHLC_00478	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
CIGDHHLC_00479	8.6e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
CIGDHHLC_00480	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
CIGDHHLC_00481	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
CIGDHHLC_00482	1e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
CIGDHHLC_00483	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_00484	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
CIGDHHLC_00485	8.32e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CIGDHHLC_00486	6.13e-100	ydaG	-	-	S	-	-	-	general stress protein
CIGDHHLC_00487	5.12e-176	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
CIGDHHLC_00488	5.19e-60	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
CIGDHHLC_00489	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
CIGDHHLC_00490	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CIGDHHLC_00491	5.12e-101	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
CIGDHHLC_00492	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
CIGDHHLC_00493	1.84e-34	-	-	-	-	-	-	-	-
CIGDHHLC_00494	2.18e-90	sdpB	-	-	S	-	-	-	Protein conserved in bacteria
CIGDHHLC_00496	6.14e-53	-	-	-	-	-	-	-	-
CIGDHHLC_00497	7.87e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CIGDHHLC_00498	1.67e-42	ydaS	-	-	S	-	-	-	membrane
CIGDHHLC_00499	7.54e-99	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
CIGDHHLC_00500	4.3e-190	ydbA	-	-	P	-	-	-	EcsC protein family
CIGDHHLC_00501	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
CIGDHHLC_00502	2.17e-78	ydbB	-	-	G	-	-	-	Cupin domain
CIGDHHLC_00503	1.49e-81	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
CIGDHHLC_00504	6.41e-197	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
CIGDHHLC_00505	4.99e-251	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
CIGDHHLC_00506	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
CIGDHHLC_00507	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
CIGDHHLC_00508	7.33e-289	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CIGDHHLC_00509	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_00511	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
CIGDHHLC_00512	2.66e-218	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_00513	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CIGDHHLC_00514	9.32e-70	ydbL	-	-	-	-	-	-	-
CIGDHHLC_00515	1.83e-280	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
CIGDHHLC_00516	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
CIGDHHLC_00518	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CIGDHHLC_00519	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
CIGDHHLC_00520	4.18e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
CIGDHHLC_00521	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CIGDHHLC_00522	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CIGDHHLC_00523	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
CIGDHHLC_00524	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
CIGDHHLC_00525	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
CIGDHHLC_00526	1.87e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CIGDHHLC_00527	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
CIGDHHLC_00528	2.07e-281	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CIGDHHLC_00529	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
CIGDHHLC_00530	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
CIGDHHLC_00531	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
CIGDHHLC_00532	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
CIGDHHLC_00533	1e-88	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
CIGDHHLC_00534	1.08e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
CIGDHHLC_00535	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
CIGDHHLC_00536	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
CIGDHHLC_00537	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CIGDHHLC_00538	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
CIGDHHLC_00539	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
CIGDHHLC_00540	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
CIGDHHLC_00548	4.46e-153	-	-	-	E	-	-	-	amino acid
CIGDHHLC_00549	9.13e-135	ywqM	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_00550	4.64e-95	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CIGDHHLC_00551	9.99e-59	-	-	-	-	-	-	-	-
CIGDHHLC_00552	5.9e-171	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CIGDHHLC_00553	1.8e-45	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
CIGDHHLC_00554	2.98e-53	-	-	-	-	-	-	-	-
CIGDHHLC_00558	3.49e-145	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
CIGDHHLC_00559	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
CIGDHHLC_00560	1.45e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
CIGDHHLC_00561	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_00563	1.8e-177	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CIGDHHLC_00564	2.44e-210	-	-	-	K	-	-	-	AraC-like ligand binding domain
CIGDHHLC_00565	2.27e-220	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CIGDHHLC_00566	7.62e-210	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
CIGDHHLC_00567	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CIGDHHLC_00568	1.34e-196	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
CIGDHHLC_00569	4.72e-134	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
CIGDHHLC_00570	4.95e-140	-	-	-	-	-	-	-	-
CIGDHHLC_00571	2.4e-41	-	-	-	S	-	-	-	SNARE associated Golgi protein
CIGDHHLC_00572	3.3e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
CIGDHHLC_00573	2.44e-110	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
CIGDHHLC_00574	4.66e-197	ydeK	-	-	EG	-	-	-	-transporter
CIGDHHLC_00575	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CIGDHHLC_00576	2.49e-95	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
CIGDHHLC_00577	1.37e-134	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
CIGDHHLC_00578	1.02e-72	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
CIGDHHLC_00579	9.32e-194	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
CIGDHHLC_00580	3e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
CIGDHHLC_00581	1.75e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CIGDHHLC_00583	8.66e-186	-	-	-	J	-	-	-	GNAT acetyltransferase
CIGDHHLC_00584	9.99e-197	-	-	-	EG	-	-	-	EamA-like transporter family
CIGDHHLC_00585	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CIGDHHLC_00586	1.54e-232	-	4.1.1.86	-	E	ko:K13745	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
CIGDHHLC_00587	4.04e-149	ydfE	-	-	S	-	-	-	Flavin reductase like domain
CIGDHHLC_00588	5.24e-159	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CIGDHHLC_00589	1.15e-20	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CIGDHHLC_00591	3.75e-249	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_00592	1.55e-140	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CIGDHHLC_00593	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
CIGDHHLC_00594	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_00597	4.26e-220	-	-	-	S	-	-	-	Alpha/beta hydrolase family
CIGDHHLC_00598	3.77e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
CIGDHHLC_00599	1.23e-188	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
CIGDHHLC_00600	2.12e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CIGDHHLC_00601	7.8e-142	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
CIGDHHLC_00602	1.29e-236	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
CIGDHHLC_00603	1.28e-61	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
CIGDHHLC_00604	2.1e-71	ydfQ	-	-	CO	-	-	-	Thioredoxin
CIGDHHLC_00605	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
CIGDHHLC_00606	3.75e-39	-	-	-	-	-	-	-	-
CIGDHHLC_00608	5e-152	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
CIGDHHLC_00609	8.96e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
CIGDHHLC_00610	1.28e-98	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CIGDHHLC_00611	5.54e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
CIGDHHLC_00612	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
CIGDHHLC_00613	2.85e-126	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGDHHLC_00614	5.76e-70	-	-	-	S	-	-	-	DoxX-like family
CIGDHHLC_00615	8.04e-111	yycN	-	-	K	-	-	-	Acetyltransferase
CIGDHHLC_00616	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
CIGDHHLC_00617	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
CIGDHHLC_00618	6.94e-117	-	-	-	S	-	-	-	DinB family
CIGDHHLC_00619	1.19e-103	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIGDHHLC_00620	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
CIGDHHLC_00621	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
CIGDHHLC_00622	1.9e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
CIGDHHLC_00623	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
CIGDHHLC_00624	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CIGDHHLC_00625	1.24e-156	ydhC	-	-	K	-	-	-	FCD
CIGDHHLC_00626	4.17e-299	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
CIGDHHLC_00627	6.49e-288	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CIGDHHLC_00628	4.28e-163	-	-	-	-	-	-	-	-
CIGDHHLC_00629	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
CIGDHHLC_00630	5.54e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
CIGDHHLC_00632	2.78e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CIGDHHLC_00633	5.22e-229	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CIGDHHLC_00634	5.93e-130	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
CIGDHHLC_00635	3.64e-254	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
CIGDHHLC_00636	2.29e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_00637	2.31e-41	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_00638	1.22e-173	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIGDHHLC_00639	1.2e-114	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIGDHHLC_00640	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CIGDHHLC_00641	2.22e-170	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
CIGDHHLC_00642	3.34e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
CIGDHHLC_00643	1.07e-09	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
CIGDHHLC_00644	1.24e-76	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
CIGDHHLC_00645	3.91e-270	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
CIGDHHLC_00646	9.18e-172	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
CIGDHHLC_00649	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
CIGDHHLC_00652	1.75e-227	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CIGDHHLC_00653	3.68e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
CIGDHHLC_00654	2.8e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
CIGDHHLC_00655	2e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CIGDHHLC_00656	1.34e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CIGDHHLC_00657	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
CIGDHHLC_00658	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CIGDHHLC_00659	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CIGDHHLC_00660	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CIGDHHLC_00661	3.55e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CIGDHHLC_00662	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
CIGDHHLC_00663	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CIGDHHLC_00664	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CIGDHHLC_00665	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CIGDHHLC_00666	1.91e-182	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIGDHHLC_00667	2.71e-61	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
CIGDHHLC_00668	3.66e-28	-	-	-	K	-	-	-	transcriptional
CIGDHHLC_00669	1.5e-26	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGDHHLC_00670	1.68e-48	-	-	-	-	-	-	-	-
CIGDHHLC_00671	1.22e-48	-	-	-	S	-	-	-	DNA binding
CIGDHHLC_00672	3.14e-110	-	-	-	-	-	-	-	-
CIGDHHLC_00677	8.41e-125	-	-	-	-	-	-	-	-
CIGDHHLC_00678	1.8e-87	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
CIGDHHLC_00680	4.69e-96	yqaL	-	-	L	-	-	-	DnaD domain protein
CIGDHHLC_00681	6.06e-102	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
CIGDHHLC_00683	2.02e-81	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
CIGDHHLC_00684	1.78e-34	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
CIGDHHLC_00687	1.19e-37	-	-	-	-	-	-	-	-
CIGDHHLC_00688	6e-147	-	-	-	-	-	-	-	-
CIGDHHLC_00690	1.84e-105	-	-	-	L	-	-	-	Transposase
CIGDHHLC_00691	7.11e-39	-	-	-	-	-	-	-	-
CIGDHHLC_00692	1.19e-66	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
CIGDHHLC_00693	5.19e-102	-	-	-	L	-	-	-	phage terminase small subunit
CIGDHHLC_00694	0.0	-	-	-	S	-	-	-	Terminase
CIGDHHLC_00696	2.64e-303	-	-	-	S	-	-	-	Phage portal protein
CIGDHHLC_00697	6.14e-151	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
CIGDHHLC_00698	1.06e-266	-	-	-	S	-	-	-	capsid protein
CIGDHHLC_00699	1.89e-34	-	-	-	-	-	-	-	-
CIGDHHLC_00700	1.4e-50	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
CIGDHHLC_00701	5.23e-52	-	-	-	S	-	-	-	Phage head-tail joining protein
CIGDHHLC_00702	8.4e-67	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
CIGDHHLC_00704	1.67e-101	-	-	-	N	-	-	-	Phage major tail protein phi13
CIGDHHLC_00705	1.77e-05	-	-	-	-	-	-	-	-
CIGDHHLC_00707	0.0	-	-	-	D	-	-	-	phage tail tape measure protein
CIGDHHLC_00708	1.19e-135	-	-	-	S	-	-	-	Phage tail protein
CIGDHHLC_00709	1.92e-275	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
CIGDHHLC_00710	8.01e-317	-	-	-	-	-	-	-	-
CIGDHHLC_00711	2.1e-250	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
CIGDHHLC_00714	1.81e-37	bhlA	-	-	S	-	-	-	BhlA holin family
CIGDHHLC_00715	3.19e-41	xhlB	-	-	S	-	-	-	SPP1 phage holin
CIGDHHLC_00716	7.81e-167	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
CIGDHHLC_00717	8.88e-87	-	-	-	S	-	-	-	Immunity protein 70
CIGDHHLC_00718	6.57e-233	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
CIGDHHLC_00720	7.52e-55	-	-	-	S	-	-	-	protein domain associated with
CIGDHHLC_00722	6.75e-38	-	-	-	K	-	-	-	Helix-turn-helix domain
CIGDHHLC_00724	5.85e-35	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
CIGDHHLC_00728	1.17e-148	-	-	-	-	-	-	-	-
CIGDHHLC_00729	5.53e-175	-	-	-	-	-	-	-	-
CIGDHHLC_00730	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
CIGDHHLC_00731	2.5e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
CIGDHHLC_00732	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
CIGDHHLC_00733	4.95e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
CIGDHHLC_00734	8.88e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
CIGDHHLC_00735	3.64e-228	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CIGDHHLC_00736	3.21e-167	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
CIGDHHLC_00737	3.61e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
CIGDHHLC_00738	4.11e-183	-	-	-	S	-	-	-	Ion transport 2 domain protein
CIGDHHLC_00739	1.91e-33	-	-	-	S	-	-	-	Ion transport 2 domain protein
CIGDHHLC_00740	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CIGDHHLC_00741	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
CIGDHHLC_00742	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
CIGDHHLC_00743	1.62e-207	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
CIGDHHLC_00744	3.26e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_00745	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_00747	9.99e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
CIGDHHLC_00748	1.46e-201	-	-	-	I	-	-	-	Alpha/beta hydrolase family
CIGDHHLC_00749	6.33e-103	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
CIGDHHLC_00750	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
CIGDHHLC_00751	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
CIGDHHLC_00752	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CIGDHHLC_00753	5.62e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
CIGDHHLC_00754	1.07e-283	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
CIGDHHLC_00755	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
CIGDHHLC_00756	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
CIGDHHLC_00757	6.3e-111	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIGDHHLC_00758	1.15e-314	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
CIGDHHLC_00759	6.6e-281	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
CIGDHHLC_00760	5.85e-165	yebC	-	-	M	-	-	-	Membrane
CIGDHHLC_00761	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_00764	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
CIGDHHLC_00765	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
CIGDHHLC_00766	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CIGDHHLC_00767	2.69e-277	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CIGDHHLC_00768	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CIGDHHLC_00769	5.86e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
CIGDHHLC_00770	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIGDHHLC_00771	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIGDHHLC_00772	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIGDHHLC_00773	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CIGDHHLC_00774	9.88e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
CIGDHHLC_00775	3.62e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CIGDHHLC_00776	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
CIGDHHLC_00777	5.45e-296	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
CIGDHHLC_00778	7.5e-92	-	-	-	K	-	-	-	helix_turn_helix ASNC type
CIGDHHLC_00779	1.49e-240	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
CIGDHHLC_00780	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
CIGDHHLC_00781	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
CIGDHHLC_00782	9.58e-244	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
CIGDHHLC_00783	6.27e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_00784	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
CIGDHHLC_00786	7.43e-160	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CIGDHHLC_00787	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
CIGDHHLC_00788	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CIGDHHLC_00789	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
CIGDHHLC_00790	2.45e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
CIGDHHLC_00791	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
CIGDHHLC_00792	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CIGDHHLC_00793	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIGDHHLC_00794	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CIGDHHLC_00795	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIGDHHLC_00796	2.08e-190	yerO	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_00797	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CIGDHHLC_00798	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CIGDHHLC_00799	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIGDHHLC_00800	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
CIGDHHLC_00804	1.59e-124	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
CIGDHHLC_00806	5.1e-36	-	-	-	-	-	-	-	-
CIGDHHLC_00807	3.39e-98	-	-	-	S	-	-	-	Protein of unknown function, DUF600
CIGDHHLC_00808	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
CIGDHHLC_00810	2.44e-127	-	-	-	L	-	-	-	endonuclease activity
CIGDHHLC_00811	1.23e-14	-	-	-	S	-	-	-	Pfam:DUF1311
CIGDHHLC_00812	4.97e-271	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
CIGDHHLC_00814	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
CIGDHHLC_00816	7.28e-132	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_00817	4.59e-101	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
CIGDHHLC_00818	1.13e-193	yesF	-	-	GM	-	-	-	NAD(P)H-binding
CIGDHHLC_00819	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
CIGDHHLC_00820	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
CIGDHHLC_00821	6.05e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
CIGDHHLC_00822	1.19e-130	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
CIGDHHLC_00823	2.56e-132	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
CIGDHHLC_00824	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_00825	7.1e-163	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
CIGDHHLC_00826	1.39e-51	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
CIGDHHLC_00827	6.85e-313	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIGDHHLC_00828	6.98e-77	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIGDHHLC_00829	3.57e-120	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIGDHHLC_00830	8.84e-211	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIGDHHLC_00831	8e-254	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
CIGDHHLC_00832	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_00833	5.05e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
CIGDHHLC_00834	1.07e-164	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
CIGDHHLC_00835	4.69e-144	-	-	-	S	-	-	-	Protein of unknown function, DUF624
CIGDHHLC_00836	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
CIGDHHLC_00837	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
CIGDHHLC_00838	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
CIGDHHLC_00839	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
CIGDHHLC_00840	2.25e-127	yetA	-	-	-	-	-	-	-
CIGDHHLC_00841	0.0	yetA	-	-	-	-	-	-	-
CIGDHHLC_00842	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIGDHHLC_00843	1.18e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
CIGDHHLC_00844	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIGDHHLC_00845	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
CIGDHHLC_00846	3.66e-157	yetF	-	-	S	-	-	-	membrane
CIGDHHLC_00847	1.57e-71	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
CIGDHHLC_00848	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIGDHHLC_00849	4.34e-44	-	-	-	-	-	-	-	-
CIGDHHLC_00850	1.52e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CIGDHHLC_00851	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
CIGDHHLC_00852	4.23e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
CIGDHHLC_00853	1.3e-38	yetM	-	-	CH	-	-	-	FAD binding domain
CIGDHHLC_00854	5.94e-131	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
CIGDHHLC_00855	1.94e-248	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
CIGDHHLC_00856	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
CIGDHHLC_00857	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
CIGDHHLC_00858	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
CIGDHHLC_00859	1.03e-238	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
CIGDHHLC_00860	2.69e-229	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
CIGDHHLC_00861	6.7e-284	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
CIGDHHLC_00862	2.34e-243	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
CIGDHHLC_00863	7.24e-267	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_00864	2.05e-165	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CIGDHHLC_00865	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
CIGDHHLC_00866	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CIGDHHLC_00867	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
CIGDHHLC_00868	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CIGDHHLC_00869	4.39e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
CIGDHHLC_00870	2.68e-97	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
CIGDHHLC_00871	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
CIGDHHLC_00872	2.1e-39	-	-	-	-	-	-	-	-
CIGDHHLC_00873	3.26e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_00874	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_00875	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CIGDHHLC_00876	1.4e-261	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
CIGDHHLC_00877	1.86e-98	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
CIGDHHLC_00878	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
CIGDHHLC_00879	2.84e-240	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
CIGDHHLC_00880	1.15e-191	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIGDHHLC_00881	2.98e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_00882	8.17e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_00883	1.94e-219	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
CIGDHHLC_00884	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
CIGDHHLC_00885	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
CIGDHHLC_00886	1.16e-305	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
CIGDHHLC_00887	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
CIGDHHLC_00888	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
CIGDHHLC_00889	2.68e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
CIGDHHLC_00890	1.62e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
CIGDHHLC_00891	1.18e-252	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
CIGDHHLC_00892	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
CIGDHHLC_00893	1.7e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
CIGDHHLC_00894	4.6e-274	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CIGDHHLC_00895	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
CIGDHHLC_00896	3.42e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_00897	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
CIGDHHLC_00898	6.9e-27	yflI	-	-	-	-	-	-	-
CIGDHHLC_00899	1.73e-64	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
CIGDHHLC_00900	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
CIGDHHLC_00901	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
CIGDHHLC_00902	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
CIGDHHLC_00903	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
CIGDHHLC_00904	1.43e-41	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
CIGDHHLC_00905	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_00906	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
CIGDHHLC_00907	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
CIGDHHLC_00908	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
CIGDHHLC_00909	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CIGDHHLC_00910	1.83e-112	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
CIGDHHLC_00911	6.93e-263	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_00912	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
CIGDHHLC_00913	5.89e-108	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIGDHHLC_00914	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
CIGDHHLC_00915	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
CIGDHHLC_00916	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_00917	5.44e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
CIGDHHLC_00918	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
CIGDHHLC_00919	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
CIGDHHLC_00920	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
CIGDHHLC_00921	3.26e-36	yfjT	-	-	-	-	-	-	-
CIGDHHLC_00922	5.95e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
CIGDHHLC_00923	7.99e-193	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
CIGDHHLC_00924	1.24e-233	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
CIGDHHLC_00925	3.92e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CIGDHHLC_00926	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIGDHHLC_00927	3.04e-59	-	-	-	S	-	-	-	YfzA-like protein
CIGDHHLC_00928	1.25e-236	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CIGDHHLC_00929	1.3e-108	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
CIGDHHLC_00931	6.48e-243	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CIGDHHLC_00932	8.81e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CIGDHHLC_00933	4.19e-265	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CIGDHHLC_00934	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CIGDHHLC_00935	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
CIGDHHLC_00936	3.9e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
CIGDHHLC_00937	2.9e-74	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
CIGDHHLC_00938	1e-105	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
CIGDHHLC_00939	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
CIGDHHLC_00940	1.02e-184	yfjC	-	-	-	-	-	-	-
CIGDHHLC_00941	1.94e-270	yfjB	-	-	-	-	-	-	-
CIGDHHLC_00942	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
CIGDHHLC_00943	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CIGDHHLC_00944	1.23e-180	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
CIGDHHLC_00945	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_00946	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CIGDHHLC_00947	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
CIGDHHLC_00948	1.93e-82	yfiD3	-	-	S	-	-	-	DoxX
CIGDHHLC_00949	2.97e-208	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
CIGDHHLC_00950	8.81e-284	baeS	-	-	T	-	-	-	Histidine kinase
CIGDHHLC_00951	5.82e-144	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
CIGDHHLC_00952	1.78e-213	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_00953	5.69e-262	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CIGDHHLC_00954	3.44e-262	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
CIGDHHLC_00955	1.89e-128	padR	-	-	K	-	-	-	transcriptional
CIGDHHLC_00956	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CIGDHHLC_00957	2.68e-252	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CIGDHHLC_00958	4.01e-139	yfiR	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_00959	1.91e-266	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
CIGDHHLC_00960	4.67e-127	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
CIGDHHLC_00961	1.11e-291	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
CIGDHHLC_00962	1.66e-21	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
CIGDHHLC_00963	4.26e-103	yfiV	-	-	K	-	-	-	transcriptional
CIGDHHLC_00964	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CIGDHHLC_00965	1.28e-229	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CIGDHHLC_00966	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_00967	5.18e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_00968	9.95e-211	yfhB	-	-	S	-	-	-	PhzF family
CIGDHHLC_00969	1.17e-137	yfhC	-	-	C	-	-	-	nitroreductase
CIGDHHLC_00970	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
CIGDHHLC_00972	2.56e-218	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
CIGDHHLC_00973	2.67e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
CIGDHHLC_00974	8.29e-59	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
CIGDHHLC_00976	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
CIGDHHLC_00977	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
CIGDHHLC_00978	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
CIGDHHLC_00979	7.22e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
CIGDHHLC_00980	6.3e-66	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
CIGDHHLC_00981	1.13e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
CIGDHHLC_00982	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
CIGDHHLC_00983	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
CIGDHHLC_00984	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
CIGDHHLC_00985	1.99e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
CIGDHHLC_00986	1.73e-48	yfhS	-	-	-	-	-	-	-
CIGDHHLC_00987	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_00988	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
CIGDHHLC_00989	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
CIGDHHLC_00990	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
CIGDHHLC_00991	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
CIGDHHLC_00992	8.86e-237	ygaE	-	-	S	-	-	-	Membrane
CIGDHHLC_00993	3.26e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
CIGDHHLC_00994	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
CIGDHHLC_00995	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
CIGDHHLC_00996	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
CIGDHHLC_00997	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
CIGDHHLC_00998	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
CIGDHHLC_01015	3.26e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_01016	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_01017	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01019	1.5e-183	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
CIGDHHLC_01020	1.58e-36	-	-	-	-	-	-	-	-
CIGDHHLC_01021	5.27e-168	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
CIGDHHLC_01022	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CIGDHHLC_01024	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
CIGDHHLC_01025	7.4e-178	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
CIGDHHLC_01026	2.79e-213	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
CIGDHHLC_01027	4.62e-187	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CIGDHHLC_01028	8.96e-274	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
CIGDHHLC_01031	1.96e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIGDHHLC_01032	6.32e-99	ygaO	-	-	-	-	-	-	-
CIGDHHLC_01033	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_01035	1.07e-144	yhzB	-	-	S	-	-	-	B3/4 domain
CIGDHHLC_01036	1.7e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CIGDHHLC_01037	9.27e-224	yhbB	-	-	S	-	-	-	Putative amidase domain
CIGDHHLC_01038	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CIGDHHLC_01039	3.97e-142	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
CIGDHHLC_01040	1.53e-94	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
CIGDHHLC_01041	3.01e-105	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
CIGDHHLC_01042	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
CIGDHHLC_01043	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
CIGDHHLC_01044	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
CIGDHHLC_01045	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
CIGDHHLC_01046	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
CIGDHHLC_01047	1.4e-127	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
CIGDHHLC_01048	3.95e-59	yhcC	-	-	-	-	-	-	-
CIGDHHLC_01049	2.06e-69	-	-	-	-	-	-	-	-
CIGDHHLC_01050	1.95e-78	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_01051	1.32e-155	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_01052	5.09e-210	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_01053	5.71e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CIGDHHLC_01054	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
CIGDHHLC_01055	4.31e-192	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CIGDHHLC_01056	4.78e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
CIGDHHLC_01057	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CIGDHHLC_01058	1.22e-249	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
CIGDHHLC_01059	1.5e-81	-	-	-	S	-	-	-	Immunity protein 70
CIGDHHLC_01063	6.72e-60	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIGDHHLC_01066	7.09e-60	yddA	-	-	-	-	-	-	-
CIGDHHLC_01070	2.61e-223	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
CIGDHHLC_01071	9.78e-54	yddC	-	-	-	-	-	-	-
CIGDHHLC_01072	6.91e-118	yddD	-	-	S	-	-	-	TcpE family
CIGDHHLC_01073	1.59e-270	yddE	-	-	S	-	-	-	AAA-like domain
CIGDHHLC_01074	2.21e-242	yddE	-	-	S	-	-	-	AAA-like domain
CIGDHHLC_01075	1.1e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
CIGDHHLC_01076	0.0	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
CIGDHHLC_01077	1.03e-237	yddH	-	-	M	-	-	-	Lysozyme-like
CIGDHHLC_01078	3.19e-111	yddI	-	-	-	-	-	-	-
CIGDHHLC_01079	3.04e-87	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
CIGDHHLC_01080	2.1e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
CIGDHHLC_01081	2.45e-83	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
CIGDHHLC_01083	9.39e-63	yhcM	-	-	-	-	-	-	-
CIGDHHLC_01084	9.32e-108	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CIGDHHLC_01085	3.38e-216	yhcP	-	-	-	-	-	-	-
CIGDHHLC_01086	7.05e-124	yhcQ	-	-	M	-	-	-	Spore coat protein
CIGDHHLC_01087	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CIGDHHLC_01088	1.25e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
CIGDHHLC_01089	8.26e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
CIGDHHLC_01090	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
CIGDHHLC_01091	7.16e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
CIGDHHLC_01092	1.24e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
CIGDHHLC_01093	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CIGDHHLC_01094	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CIGDHHLC_01095	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CIGDHHLC_01096	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CIGDHHLC_01097	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CIGDHHLC_01098	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CIGDHHLC_01099	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
CIGDHHLC_01100	1.54e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_01101	9.41e-145	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CIGDHHLC_01102	1.9e-115	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
CIGDHHLC_01103	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
CIGDHHLC_01104	1.02e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
CIGDHHLC_01105	1.32e-272	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
CIGDHHLC_01106	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
CIGDHHLC_01108	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01109	5.04e-305	ygxB	-	-	M	-	-	-	Conserved TM helix
CIGDHHLC_01110	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
CIGDHHLC_01111	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
CIGDHHLC_01112	5.92e-203	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
CIGDHHLC_01113	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_01114	1.45e-258	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
CIGDHHLC_01115	3.72e-204	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_01116	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
CIGDHHLC_01117	2.89e-308	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CIGDHHLC_01118	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CIGDHHLC_01119	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIGDHHLC_01120	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
CIGDHHLC_01121	2.05e-256	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
CIGDHHLC_01122	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIGDHHLC_01123	1.12e-242	yhdN	-	-	C	-	-	-	Aldo keto reductase
CIGDHHLC_01124	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CIGDHHLC_01125	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
CIGDHHLC_01126	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
CIGDHHLC_01127	3.35e-92	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
CIGDHHLC_01128	3.62e-171	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
CIGDHHLC_01129	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
CIGDHHLC_01130	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIGDHHLC_01131	5.83e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIGDHHLC_01132	9.03e-173	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
CIGDHHLC_01133	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
CIGDHHLC_01134	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
CIGDHHLC_01135	9.4e-177	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CIGDHHLC_01136	9.72e-192	nodB1	-	-	G	-	-	-	deacetylase
CIGDHHLC_01137	2.6e-196	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
CIGDHHLC_01138	3.45e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
CIGDHHLC_01139	1.53e-108	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
CIGDHHLC_01140	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
CIGDHHLC_01141	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
CIGDHHLC_01142	1.29e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
CIGDHHLC_01143	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
CIGDHHLC_01144	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
CIGDHHLC_01145	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
CIGDHHLC_01146	2.77e-275	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
CIGDHHLC_01147	1.19e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
CIGDHHLC_01148	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
CIGDHHLC_01149	2.11e-131	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
CIGDHHLC_01150	3.3e-92	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
CIGDHHLC_01151	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
CIGDHHLC_01152	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
CIGDHHLC_01153	4.36e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
CIGDHHLC_01154	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
CIGDHHLC_01156	1.45e-170	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
CIGDHHLC_01157	1.89e-35	-	-	-	S	-	-	-	YhzD-like protein
CIGDHHLC_01158	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_01159	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
CIGDHHLC_01160	8.42e-302	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
CIGDHHLC_01161	0.0	yhaN	-	-	L	-	-	-	AAA domain
CIGDHHLC_01162	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
CIGDHHLC_01163	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
CIGDHHLC_01164	4.7e-161	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CIGDHHLC_01165	5.71e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
CIGDHHLC_01166	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
CIGDHHLC_01167	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
CIGDHHLC_01168	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
CIGDHHLC_01169	1.28e-103	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
CIGDHHLC_01170	1.84e-262	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CIGDHHLC_01171	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CIGDHHLC_01172	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
CIGDHHLC_01173	4.23e-270	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CIGDHHLC_01174	2.89e-161	ecsC	-	-	S	-	-	-	EcsC protein family
CIGDHHLC_01175	1.27e-290	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CIGDHHLC_01176	2.7e-312	yhfA	-	-	C	-	-	-	membrane
CIGDHHLC_01177	1e-44	-	-	-	C	-	-	-	Rubrerythrin
CIGDHHLC_01178	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
CIGDHHLC_01179	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
CIGDHHLC_01180	1.24e-257	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CIGDHHLC_01181	3.28e-229	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
CIGDHHLC_01182	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CIGDHHLC_01183	6.76e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_01184	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
CIGDHHLC_01186	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01187	1.77e-236	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CIGDHHLC_01188	3.8e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
CIGDHHLC_01190	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
CIGDHHLC_01191	1.79e-92	-	-	-	S	-	-	-	ASCH
CIGDHHLC_01192	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CIGDHHLC_01193	1.63e-180	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
CIGDHHLC_01194	4.06e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
CIGDHHLC_01195	1.01e-141	yhfK	-	-	GM	-	-	-	NmrA-like family
CIGDHHLC_01196	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
CIGDHHLC_01197	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01198	7.65e-83	yhfM	-	-	-	-	-	-	-
CIGDHHLC_01199	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
CIGDHHLC_01200	6.91e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
CIGDHHLC_01201	5.98e-100	-	-	-	K	-	-	-	acetyltransferase
CIGDHHLC_01202	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
CIGDHHLC_01203	3.23e-222	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
CIGDHHLC_01204	5.6e-173	-	-	-	L	-	-	-	Integrase core domain
CIGDHHLC_01205	7.55e-59	orfX1	-	-	L	-	-	-	Transposase
CIGDHHLC_01206	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
CIGDHHLC_01207	6.04e-250	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
CIGDHHLC_01208	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
CIGDHHLC_01209	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
CIGDHHLC_01210	6.15e-259	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
CIGDHHLC_01211	1.18e-120	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
CIGDHHLC_01212	4.28e-149	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
CIGDHHLC_01213	3.74e-37	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
CIGDHHLC_01214	3.72e-202	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_01215	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
CIGDHHLC_01216	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
CIGDHHLC_01217	6.46e-210	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
CIGDHHLC_01218	4.64e-53	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
CIGDHHLC_01219	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CIGDHHLC_01220	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
CIGDHHLC_01221	4.13e-78	yhjD	-	-	-	-	-	-	-
CIGDHHLC_01222	2.82e-140	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
CIGDHHLC_01223	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CIGDHHLC_01224	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
CIGDHHLC_01225	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIGDHHLC_01228	3.5e-269	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
CIGDHHLC_01229	9.38e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
CIGDHHLC_01230	8.81e-204	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
CIGDHHLC_01231	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
CIGDHHLC_01232	5.09e-238	yhjM	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_01233	5.04e-259	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
CIGDHHLC_01234	1.36e-267	-	-	-	EGP	-	-	-	Transmembrane secretion effector
CIGDHHLC_01235	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
CIGDHHLC_01236	6.29e-100	yhjR	-	-	S	-	-	-	Rubrerythrin
CIGDHHLC_01237	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
CIGDHHLC_01238	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
CIGDHHLC_01239	3.84e-278	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CIGDHHLC_01240	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
CIGDHHLC_01241	7.78e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
CIGDHHLC_01242	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
CIGDHHLC_01243	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
CIGDHHLC_01244	1.49e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
CIGDHHLC_01245	1e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
CIGDHHLC_01246	1.02e-46	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
CIGDHHLC_01247	7.41e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
CIGDHHLC_01248	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
CIGDHHLC_01249	1.88e-222	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
CIGDHHLC_01250	3.11e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
CIGDHHLC_01251	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
CIGDHHLC_01252	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
CIGDHHLC_01254	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01255	6.1e-131	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
CIGDHHLC_01256	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
CIGDHHLC_01257	3.44e-142	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
CIGDHHLC_01258	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
CIGDHHLC_01259	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_01260	8.71e-234	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIGDHHLC_01261	5.32e-242	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
CIGDHHLC_01262	9.94e-120	yisT	-	-	S	-	-	-	DinB family
CIGDHHLC_01263	5.19e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
CIGDHHLC_01264	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CIGDHHLC_01265	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
CIGDHHLC_01266	1.52e-197	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CIGDHHLC_01267	1.77e-96	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CIGDHHLC_01268	2.95e-91	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
CIGDHHLC_01269	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
CIGDHHLC_01270	1.75e-76	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
CIGDHHLC_01271	3.91e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
CIGDHHLC_01272	2.41e-121	-	-	-	-	-	-	-	-
CIGDHHLC_01273	1.42e-218	-	-	-	-	-	-	-	-
CIGDHHLC_01274	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
CIGDHHLC_01275	8.46e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
CIGDHHLC_01276	2.9e-118	-	-	-	-	-	-	-	-
CIGDHHLC_01277	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
CIGDHHLC_01278	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
CIGDHHLC_01279	4.16e-198	yitS	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_01280	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
CIGDHHLC_01281	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
CIGDHHLC_01282	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
CIGDHHLC_01283	1.92e-08	-	-	-	-	-	-	-	-
CIGDHHLC_01284	1.07e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
CIGDHHLC_01285	1.19e-183	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
CIGDHHLC_01286	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
CIGDHHLC_01287	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
CIGDHHLC_01288	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
CIGDHHLC_01289	5.71e-69	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
CIGDHHLC_01290	1.68e-37	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
CIGDHHLC_01291	3.52e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CIGDHHLC_01292	1.37e-290	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CIGDHHLC_01293	1.81e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
CIGDHHLC_01294	1.14e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
CIGDHHLC_01295	3.3e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CIGDHHLC_01296	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
CIGDHHLC_01297	3.01e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CIGDHHLC_01298	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_01299	3.26e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_01300	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
CIGDHHLC_01301	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
CIGDHHLC_01302	5.69e-181	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
CIGDHHLC_01303	5.2e-132	yjaV	-	-	-	-	-	-	-
CIGDHHLC_01304	5.26e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
CIGDHHLC_01305	8.86e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
CIGDHHLC_01306	2.67e-38	yjzB	-	-	-	-	-	-	-
CIGDHHLC_01307	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CIGDHHLC_01308	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CIGDHHLC_01309	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
CIGDHHLC_01310	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGDHHLC_01311	2.82e-235	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGDHHLC_01312	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
CIGDHHLC_01313	1.04e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIGDHHLC_01314	8.44e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIGDHHLC_01315	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
CIGDHHLC_01316	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
CIGDHHLC_01317	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CIGDHHLC_01318	3.44e-211	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIGDHHLC_01319	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIGDHHLC_01320	3.92e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGDHHLC_01321	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGDHHLC_01322	9.66e-267	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIGDHHLC_01323	2.77e-54	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIGDHHLC_01324	1.41e-63	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIGDHHLC_01325	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CIGDHHLC_01326	4.1e-143	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
CIGDHHLC_01327	3.98e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CIGDHHLC_01328	9.9e-279	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
CIGDHHLC_01329	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
CIGDHHLC_01330	2.68e-28	-	-	-	-	-	-	-	-
CIGDHHLC_01331	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
CIGDHHLC_01332	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
CIGDHHLC_01333	3.61e-122	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CIGDHHLC_01334	7.02e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_01335	4.41e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
CIGDHHLC_01336	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
CIGDHHLC_01337	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CIGDHHLC_01338	3.01e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
CIGDHHLC_01339	1.15e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
CIGDHHLC_01340	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CIGDHHLC_01341	1.91e-175	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CIGDHHLC_01342	4.49e-136	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
CIGDHHLC_01343	1.73e-272	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
CIGDHHLC_01344	2.56e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
CIGDHHLC_01345	1.86e-171	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CIGDHHLC_01346	2.41e-235	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CIGDHHLC_01347	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CIGDHHLC_01348	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
CIGDHHLC_01349	2.09e-103	yjbX	-	-	S	-	-	-	Spore coat protein
CIGDHHLC_01350	3.92e-107	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
CIGDHHLC_01351	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
CIGDHHLC_01352	1.03e-62	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
CIGDHHLC_01353	1.51e-18	cotW	-	-	-	ko:K06341	-	ko00000	-
CIGDHHLC_01355	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
CIGDHHLC_01358	5.39e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
CIGDHHLC_01359	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CIGDHHLC_01360	6.31e-51	-	-	-	-	-	-	-	-
CIGDHHLC_01361	2.22e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIGDHHLC_01362	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
CIGDHHLC_01363	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
CIGDHHLC_01364	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
CIGDHHLC_01365	1.84e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
CIGDHHLC_01366	6.86e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
CIGDHHLC_01367	8.25e-271	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
CIGDHHLC_01369	2.75e-31	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIGDHHLC_01370	3.95e-23	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIGDHHLC_01371	3.48e-43	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
CIGDHHLC_01373	1.19e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
CIGDHHLC_01374	5.33e-85	-	-	-	-	-	-	-	-
CIGDHHLC_01375	6.49e-58	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGDHHLC_01376	8.62e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGDHHLC_01377	7.6e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
CIGDHHLC_01378	2.09e-103	-	-	-	-	-	-	-	-
CIGDHHLC_01379	4.63e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_01380	8.41e-184	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_01381	1.87e-96	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CIGDHHLC_01382	8.18e-07	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
CIGDHHLC_01383	2.45e-34	-	-	-	K	-	-	-	Helix-turn-helix domain
CIGDHHLC_01384	1.14e-20	-	-	-	S	-	-	-	peptidoglycan catabolic process
CIGDHHLC_01385	7.12e-37	-	-	-	-	-	-	-	-
CIGDHHLC_01386	8.25e-61	-	-	-	S	-	-	-	Restriction endonuclease
CIGDHHLC_01387	1.33e-160	ynaC	-	-	-	-	-	-	-
CIGDHHLC_01388	2.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
CIGDHHLC_01389	1.03e-305	-	-	-	I	-	-	-	Pfam Lipase (class 3)
CIGDHHLC_01390	9.96e-22	-	-	-	-	-	-	-	-
CIGDHHLC_01391	3.86e-10	-	-	-	S	-	-	-	Family of unknown function (DUF5316)
CIGDHHLC_01393	8.21e-15	-	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_01401	1.12e-33	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
CIGDHHLC_01402	1.08e-60	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
CIGDHHLC_01403	3.01e-60	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
CIGDHHLC_01404	2.43e-58	yjcN	-	-	-	-	-	-	-
CIGDHHLC_01405	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
CIGDHHLC_01406	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_01407	8.8e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
CIGDHHLC_01408	3.33e-72	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
CIGDHHLC_01409	4.73e-272	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
CIGDHHLC_01410	2.17e-118	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CIGDHHLC_01412	9.69e-104	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CIGDHHLC_01413	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
CIGDHHLC_01414	2.7e-68	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
CIGDHHLC_01415	8.79e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CIGDHHLC_01417	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
CIGDHHLC_01418	9.03e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
CIGDHHLC_01419	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
CIGDHHLC_01420	1.93e-62	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
CIGDHHLC_01421	3.15e-136	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
CIGDHHLC_01422	2.8e-89	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
CIGDHHLC_01423	4.08e-132	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
CIGDHHLC_01424	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
CIGDHHLC_01425	5.25e-113	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
CIGDHHLC_01427	8.38e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
CIGDHHLC_01429	4.06e-287	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
CIGDHHLC_01430	1.76e-279	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CIGDHHLC_01431	1.11e-41	-	-	-	-	-	-	-	-
CIGDHHLC_01432	5.02e-188	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
CIGDHHLC_01433	2.1e-13	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01434	1.15e-107	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01435	1.42e-109	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01437	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
CIGDHHLC_01438	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIGDHHLC_01439	8.95e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
CIGDHHLC_01440	1.26e-20	yjlB	-	-	S	-	-	-	Cupin domain
CIGDHHLC_01441	4.85e-54	yjlB	-	-	S	-	-	-	Cupin domain
CIGDHHLC_01442	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
CIGDHHLC_01443	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CIGDHHLC_01444	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
CIGDHHLC_01445	1.13e-165	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
CIGDHHLC_01446	8.14e-128	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
CIGDHHLC_01447	1.03e-241	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
CIGDHHLC_01448	1.53e-244	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
CIGDHHLC_01449	1.08e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
CIGDHHLC_01450	1.83e-194	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_01451	4.58e-288	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
CIGDHHLC_01452	1.15e-236	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
CIGDHHLC_01453	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
CIGDHHLC_01454	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
CIGDHHLC_01455	4.56e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CIGDHHLC_01456	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01458	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
CIGDHHLC_01459	2.47e-268	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
CIGDHHLC_01460	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_01461	3.26e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_01462	8.59e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
CIGDHHLC_01464	1.09e-34	-	-	-	S	-	-	-	YCII-related domain
CIGDHHLC_01465	3.09e-217	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
CIGDHHLC_01466	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
CIGDHHLC_01467	1.11e-138	yjqB	-	-	S	-	-	-	Pfam:DUF867
CIGDHHLC_01468	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
CIGDHHLC_01469	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
CIGDHHLC_01470	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGDHHLC_01472	2.52e-201	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
CIGDHHLC_01473	8.72e-152	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
CIGDHHLC_01478	8.12e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CIGDHHLC_01479	1.18e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
CIGDHHLC_01480	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
CIGDHHLC_01481	0.0	yqbA	-	-	S	-	-	-	portal protein
CIGDHHLC_01482	4.02e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
CIGDHHLC_01483	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
CIGDHHLC_01484	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
CIGDHHLC_01485	7.93e-82	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
CIGDHHLC_01486	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
CIGDHHLC_01487	2.87e-101	xkdJ	-	-	-	-	-	-	-
CIGDHHLC_01488	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
CIGDHHLC_01489	2.45e-98	xkdM	-	-	S	-	-	-	Phage tail tube protein
CIGDHHLC_01490	9.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
CIGDHHLC_01491	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
CIGDHHLC_01492	1.73e-151	xkdP	-	-	S	-	-	-	Lysin motif
CIGDHHLC_01493	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
CIGDHHLC_01494	4.32e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
CIGDHHLC_01495	3.82e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
CIGDHHLC_01496	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CIGDHHLC_01497	2.33e-130	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
CIGDHHLC_01498	4.43e-56	-	-	-	-	-	-	-	-
CIGDHHLC_01499	0.0	-	-	-	-	-	-	-	-
CIGDHHLC_01500	2.7e-68	xkdW	-	-	S	-	-	-	XkdW protein
CIGDHHLC_01501	6.35e-31	xkdX	-	-	-	-	-	-	-
CIGDHHLC_01502	9.79e-195	xepA	-	-	-	-	-	-	-
CIGDHHLC_01503	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
CIGDHHLC_01504	1.15e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
CIGDHHLC_01505	3.2e-209	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
CIGDHHLC_01506	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
CIGDHHLC_01507	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
CIGDHHLC_01508	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
CIGDHHLC_01509	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
CIGDHHLC_01511	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01512	1.81e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
CIGDHHLC_01513	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
CIGDHHLC_01514	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CIGDHHLC_01515	1.28e-228	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
CIGDHHLC_01517	2.73e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CIGDHHLC_01518	4.95e-180	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
CIGDHHLC_01519	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
CIGDHHLC_01520	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIGDHHLC_01521	8.28e-222	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIGDHHLC_01522	7.78e-236	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGDHHLC_01523	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CIGDHHLC_01525	5.33e-222	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
CIGDHHLC_01526	3.21e-251	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
CIGDHHLC_01527	4.03e-207	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CIGDHHLC_01528	8.44e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGDHHLC_01529	5.69e-261	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
CIGDHHLC_01530	9.79e-102	ykgA	-	-	E	-	-	-	Amidinotransferase
CIGDHHLC_01531	5.42e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
CIGDHHLC_01532	4.21e-286	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CIGDHHLC_01533	9.93e-15	-	-	-	-	-	-	-	-
CIGDHHLC_01534	1.32e-165	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
CIGDHHLC_01535	2.51e-125	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
CIGDHHLC_01536	6.97e-126	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CIGDHHLC_01537	2.99e-71	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
CIGDHHLC_01538	1.94e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
CIGDHHLC_01539	1.66e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
CIGDHHLC_01540	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CIGDHHLC_01541	4.59e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CIGDHHLC_01542	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
CIGDHHLC_01543	1.66e-96	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
CIGDHHLC_01544	4.72e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
CIGDHHLC_01545	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
CIGDHHLC_01546	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CIGDHHLC_01547	6.07e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
CIGDHHLC_01548	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CIGDHHLC_01549	5.18e-173	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CIGDHHLC_01550	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_01551	3.99e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
CIGDHHLC_01552	4.05e-141	ykoF	-	-	S	-	-	-	YKOF-related Family
CIGDHHLC_01553	1.68e-156	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_01554	6.05e-307	ykoH	-	-	T	-	-	-	Histidine kinase
CIGDHHLC_01555	7.88e-145	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
CIGDHHLC_01556	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
CIGDHHLC_01557	1.45e-08	-	-	-	-	-	-	-	-
CIGDHHLC_01559	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
CIGDHHLC_01560	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
CIGDHHLC_01561	1.63e-25	-	-	-	-	-	-	-	-
CIGDHHLC_01562	3.04e-36	ykoL	-	-	-	-	-	-	-
CIGDHHLC_01563	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
CIGDHHLC_01564	6.33e-277	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
CIGDHHLC_01565	2.57e-122	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
CIGDHHLC_01566	1.2e-195	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
CIGDHHLC_01567	0.0	ykoS	-	-	-	-	-	-	-
CIGDHHLC_01568	9.49e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
CIGDHHLC_01569	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
CIGDHHLC_01570	7.24e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CIGDHHLC_01571	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
CIGDHHLC_01572	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
CIGDHHLC_01573	1.33e-226	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
CIGDHHLC_01574	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CIGDHHLC_01575	3.83e-204	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
CIGDHHLC_01576	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
CIGDHHLC_01577	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
CIGDHHLC_01578	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
CIGDHHLC_01579	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
CIGDHHLC_01581	4.83e-30	ykzE	-	-	-	-	-	-	-
CIGDHHLC_01582	4.75e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
CIGDHHLC_01583	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_01584	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CIGDHHLC_01586	3.8e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CIGDHHLC_01587	7.07e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CIGDHHLC_01588	3.86e-191	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CIGDHHLC_01589	6.84e-296	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CIGDHHLC_01590	2.79e-294	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
CIGDHHLC_01591	7.2e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CIGDHHLC_01592	1.24e-144	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
CIGDHHLC_01593	1.02e-121	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CIGDHHLC_01594	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
CIGDHHLC_01596	5.87e-74	eag	-	-	-	-	-	-	-
CIGDHHLC_01597	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
CIGDHHLC_01598	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
CIGDHHLC_01599	1.51e-166	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
CIGDHHLC_01600	9.19e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
CIGDHHLC_01601	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
CIGDHHLC_01602	8.23e-228	ykvI	-	-	S	-	-	-	membrane
CIGDHHLC_01603	2.61e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CIGDHHLC_01604	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
CIGDHHLC_01605	2.41e-177	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CIGDHHLC_01606	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CIGDHHLC_01607	8.95e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
CIGDHHLC_01608	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_01609	2.6e-39	-	-	-	-	-	-	-	-
CIGDHHLC_01610	1.83e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
CIGDHHLC_01611	6.46e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CIGDHHLC_01612	1.12e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
CIGDHHLC_01613	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
CIGDHHLC_01614	3.99e-09	-	-	-	-	-	-	-	-
CIGDHHLC_01615	3.19e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
CIGDHHLC_01616	2.21e-228	ykvZ	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_01617	1.97e-167	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
CIGDHHLC_01618	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_01619	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
CIGDHHLC_01620	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIGDHHLC_01621	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_01622	5.86e-255	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
CIGDHHLC_01623	6.21e-162	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIGDHHLC_01624	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
CIGDHHLC_01625	4.02e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
CIGDHHLC_01626	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01628	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
CIGDHHLC_01629	8.32e-151	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
CIGDHHLC_01630	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CIGDHHLC_01631	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_01632	1.78e-284	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CIGDHHLC_01633	1.05e-22	-	-	-	-	-	-	-	-
CIGDHHLC_01634	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
CIGDHHLC_01635	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
CIGDHHLC_01636	2.55e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_01637	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_01638	1.42e-211	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
CIGDHHLC_01639	2.6e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_01640	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
CIGDHHLC_01641	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_01642	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
CIGDHHLC_01643	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
CIGDHHLC_01644	6.01e-99	ykuL	-	-	S	-	-	-	CBS domain
CIGDHHLC_01645	7.61e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_01646	6.35e-113	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
CIGDHHLC_01647	1.74e-222	ykuO	-	-	-	-	-	-	-
CIGDHHLC_01648	2.95e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
CIGDHHLC_01649	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CIGDHHLC_01650	4.43e-273	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CIGDHHLC_01651	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
CIGDHHLC_01652	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
CIGDHHLC_01653	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
CIGDHHLC_01654	4.23e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
CIGDHHLC_01655	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
CIGDHHLC_01656	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_01657	4.63e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_01658	9.46e-198	yknT	-	-	-	ko:K06437	-	ko00000	-
CIGDHHLC_01659	9.21e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CIGDHHLC_01660	7.59e-245	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CIGDHHLC_01661	7.12e-312	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
CIGDHHLC_01662	8.11e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
CIGDHHLC_01663	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
CIGDHHLC_01664	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CIGDHHLC_01665	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
CIGDHHLC_01666	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
CIGDHHLC_01667	1.31e-150	yknW	-	-	S	-	-	-	Yip1 domain
CIGDHHLC_01668	8.16e-234	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIGDHHLC_01669	3.53e-159	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_01670	5.51e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
CIGDHHLC_01671	1.75e-174	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_01672	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
CIGDHHLC_01673	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
CIGDHHLC_01674	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CIGDHHLC_01675	5.43e-52	ykoA	-	-	-	-	-	-	-
CIGDHHLC_01676	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CIGDHHLC_01677	1.93e-213	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIGDHHLC_01678	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01679	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
CIGDHHLC_01680	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
CIGDHHLC_01681	8.77e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
CIGDHHLC_01682	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
CIGDHHLC_01683	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
CIGDHHLC_01684	8.84e-206	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
CIGDHHLC_01685	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
CIGDHHLC_01686	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CIGDHHLC_01687	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIGDHHLC_01688	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
CIGDHHLC_01689	8.28e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
CIGDHHLC_01690	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CIGDHHLC_01691	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
CIGDHHLC_01692	1.42e-145	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
CIGDHHLC_01693	1.51e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CIGDHHLC_01694	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CIGDHHLC_01695	5.96e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CIGDHHLC_01696	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CIGDHHLC_01697	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
CIGDHHLC_01699	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01700	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
CIGDHHLC_01701	6.37e-55	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
CIGDHHLC_01702	2.15e-151	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
CIGDHHLC_01703	4.48e-35	ykzI	-	-	-	-	-	-	-
CIGDHHLC_01704	2.61e-192	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
CIGDHHLC_01705	1.17e-97	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
CIGDHHLC_01706	1.01e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CIGDHHLC_01707	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
CIGDHHLC_01708	0.0	ylaA	-	-	-	-	-	-	-
CIGDHHLC_01709	1.44e-56	ylaB	-	-	-	-	-	-	-
CIGDHHLC_01710	3.56e-51	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIGDHHLC_01712	1.74e-57	ylaE	-	-	-	-	-	-	-
CIGDHHLC_01713	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
CIGDHHLC_01714	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
CIGDHHLC_01715	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
CIGDHHLC_01716	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_01717	2.44e-126	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CIGDHHLC_01718	1.41e-315	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
CIGDHHLC_01719	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CIGDHHLC_01720	3.49e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
CIGDHHLC_01721	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
CIGDHHLC_01722	2.35e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
CIGDHHLC_01723	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CIGDHHLC_01725	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01726	4.72e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
CIGDHHLC_01727	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CIGDHHLC_01728	9.7e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
CIGDHHLC_01729	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CIGDHHLC_01730	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
CIGDHHLC_01731	1.75e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
CIGDHHLC_01732	9.56e-211	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
CIGDHHLC_01733	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
CIGDHHLC_01734	1.53e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
CIGDHHLC_01735	4.39e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
CIGDHHLC_01736	3.78e-88	ylbD	-	-	S	-	-	-	Putative coat protein
CIGDHHLC_01737	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
CIGDHHLC_01738	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
CIGDHHLC_01739	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
CIGDHHLC_01740	1.43e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
CIGDHHLC_01741	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CIGDHHLC_01742	9.11e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
CIGDHHLC_01743	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
CIGDHHLC_01744	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
CIGDHHLC_01745	1.67e-291	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
CIGDHHLC_01747	1.15e-115	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
CIGDHHLC_01748	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
CIGDHHLC_01749	1.35e-106	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
CIGDHHLC_01750	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
CIGDHHLC_01751	3.22e-214	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIGDHHLC_01752	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CIGDHHLC_01753	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
CIGDHHLC_01754	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CIGDHHLC_01755	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
CIGDHHLC_01756	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CIGDHHLC_01757	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
CIGDHHLC_01758	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIGDHHLC_01759	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CIGDHHLC_01760	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CIGDHHLC_01761	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
CIGDHHLC_01762	3.15e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CIGDHHLC_01763	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
CIGDHHLC_01764	2.77e-177	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CIGDHHLC_01765	1.35e-143	ylxW	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_01766	8.67e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_01767	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
CIGDHHLC_01768	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CIGDHHLC_01769	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CIGDHHLC_01770	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
CIGDHHLC_01772	3.49e-219	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
CIGDHHLC_01773	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CIGDHHLC_01774	6.57e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CIGDHHLC_01775	6.37e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
CIGDHHLC_01776	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
CIGDHHLC_01777	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
CIGDHHLC_01778	7.53e-203	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
CIGDHHLC_01779	3.15e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CIGDHHLC_01780	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CIGDHHLC_01781	1.74e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
CIGDHHLC_01782	2.03e-176	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
CIGDHHLC_01783	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
CIGDHHLC_01784	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CIGDHHLC_01785	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01787	9.18e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
CIGDHHLC_01788	3.85e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CIGDHHLC_01789	2.38e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CIGDHHLC_01790	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CIGDHHLC_01791	1.3e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
CIGDHHLC_01792	1.04e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
CIGDHHLC_01793	4.86e-316	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CIGDHHLC_01794	3.76e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CIGDHHLC_01795	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
CIGDHHLC_01796	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CIGDHHLC_01797	4.97e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CIGDHHLC_01798	2.67e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CIGDHHLC_01799	3e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CIGDHHLC_01800	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
CIGDHHLC_01801	2.1e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
CIGDHHLC_01802	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
CIGDHHLC_01803	5.56e-142	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
CIGDHHLC_01804	6.89e-184	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
CIGDHHLC_01805	2.06e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
CIGDHHLC_01806	9.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
CIGDHHLC_01807	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
CIGDHHLC_01808	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
CIGDHHLC_01809	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
CIGDHHLC_01810	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
CIGDHHLC_01811	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CIGDHHLC_01812	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CIGDHHLC_01813	5.13e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CIGDHHLC_01814	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CIGDHHLC_01815	7.97e-108	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CIGDHHLC_01816	4.09e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CIGDHHLC_01817	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CIGDHHLC_01818	2.07e-261	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CIGDHHLC_01819	1.38e-177	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
CIGDHHLC_01820	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
CIGDHHLC_01821	1.37e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CIGDHHLC_01822	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
CIGDHHLC_01823	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
CIGDHHLC_01824	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
CIGDHHLC_01825	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_01826	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
CIGDHHLC_01827	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
CIGDHHLC_01828	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
CIGDHHLC_01829	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CIGDHHLC_01830	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
CIGDHHLC_01831	1.68e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CIGDHHLC_01832	4.39e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
CIGDHHLC_01833	2.88e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
CIGDHHLC_01834	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIGDHHLC_01835	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CIGDHHLC_01836	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
CIGDHHLC_01837	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CIGDHHLC_01838	1.67e-114	-	-	-	-	-	-	-	-
CIGDHHLC_01839	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CIGDHHLC_01840	1.13e-307	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CIGDHHLC_01841	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
CIGDHHLC_01842	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
CIGDHHLC_01843	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
CIGDHHLC_01844	7.5e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CIGDHHLC_01845	1.98e-176	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
CIGDHHLC_01846	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CIGDHHLC_01847	5.7e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CIGDHHLC_01848	5.83e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIGDHHLC_01849	0.0	ylqG	-	-	-	-	-	-	-
CIGDHHLC_01850	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
CIGDHHLC_01851	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CIGDHHLC_01852	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CIGDHHLC_01853	3.48e-213	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
CIGDHHLC_01854	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CIGDHHLC_01855	2.22e-313	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CIGDHHLC_01856	6.51e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
CIGDHHLC_01857	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CIGDHHLC_01858	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CIGDHHLC_01859	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CIGDHHLC_01860	9.37e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
CIGDHHLC_01861	2.16e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
CIGDHHLC_01862	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
CIGDHHLC_01863	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
CIGDHHLC_01864	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CIGDHHLC_01865	4.51e-143	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
CIGDHHLC_01866	3.5e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
CIGDHHLC_01867	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
CIGDHHLC_01868	1.02e-83	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
CIGDHHLC_01869	1.36e-306	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
CIGDHHLC_01870	5.67e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
CIGDHHLC_01871	3.12e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
CIGDHHLC_01872	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
CIGDHHLC_01873	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CIGDHHLC_01874	1.6e-252	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CIGDHHLC_01875	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
CIGDHHLC_01876	3.99e-130	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
CIGDHHLC_01877	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
CIGDHHLC_01878	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
CIGDHHLC_01879	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
CIGDHHLC_01880	3.89e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CIGDHHLC_01881	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CIGDHHLC_01882	8.03e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
CIGDHHLC_01883	1.81e-199	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
CIGDHHLC_01884	1.49e-251	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
CIGDHHLC_01885	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
CIGDHHLC_01886	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
CIGDHHLC_01887	3.42e-142	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
CIGDHHLC_01888	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
CIGDHHLC_01889	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CIGDHHLC_01890	6.91e-101	ylxL	-	-	-	-	-	-	-
CIGDHHLC_01891	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
CIGDHHLC_01892	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CIGDHHLC_01893	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
CIGDHHLC_01894	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CIGDHHLC_01895	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CIGDHHLC_01896	4.74e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
CIGDHHLC_01897	1.14e-275	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CIGDHHLC_01898	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
CIGDHHLC_01899	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CIGDHHLC_01900	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIGDHHLC_01901	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
CIGDHHLC_01902	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
CIGDHHLC_01903	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
CIGDHHLC_01904	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
CIGDHHLC_01905	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CIGDHHLC_01906	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
CIGDHHLC_01907	5.03e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CIGDHHLC_01908	1.73e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CIGDHHLC_01909	2.22e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
CIGDHHLC_01910	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CIGDHHLC_01911	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CIGDHHLC_01912	2.4e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
CIGDHHLC_01913	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
CIGDHHLC_01914	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
CIGDHHLC_01915	2.16e-207	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
CIGDHHLC_01916	1.36e-139	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
CIGDHHLC_01917	4.77e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CIGDHHLC_01918	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
CIGDHHLC_01919	9.08e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIGDHHLC_01920	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIGDHHLC_01921	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
CIGDHHLC_01922	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
CIGDHHLC_01923	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CIGDHHLC_01924	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_01925	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_01926	9.47e-299	albE	-	-	S	-	-	-	Peptidase M16
CIGDHHLC_01927	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
CIGDHHLC_01928	6.33e-168	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
CIGDHHLC_01929	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
CIGDHHLC_01930	5.56e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
CIGDHHLC_01931	3.56e-176	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
CIGDHHLC_01932	1.36e-131	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIGDHHLC_01933	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
CIGDHHLC_01934	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CIGDHHLC_01935	1.82e-276	pbpX	-	-	V	-	-	-	Beta-lactamase
CIGDHHLC_01936	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
CIGDHHLC_01937	3.57e-194	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
CIGDHHLC_01938	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
CIGDHHLC_01939	1.96e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
CIGDHHLC_01940	1.62e-275	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CIGDHHLC_01941	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_01942	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CIGDHHLC_01943	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
CIGDHHLC_01944	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
CIGDHHLC_01945	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CIGDHHLC_01946	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CIGDHHLC_01951	5.52e-31	-	-	-	M	-	-	-	ArpU family transcriptional regulator
CIGDHHLC_01952	5.89e-58	-	-	-	L	-	-	-	Phage integrase family
CIGDHHLC_01959	5.53e-84	-	-	-	S	-	-	-	HNH endonuclease
CIGDHHLC_01960	8.79e-12	-	-	-	-	-	-	-	-
CIGDHHLC_01961	4.09e-73	-	-	-	S	-	-	-	Phage terminase, small subunit
CIGDHHLC_01963	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
CIGDHHLC_01964	2.23e-90	-	-	-	S	-	-	-	Regulatory protein YrvL
CIGDHHLC_01965	9.3e-126	ymcC	-	-	S	-	-	-	Membrane
CIGDHHLC_01966	1.02e-134	pksA	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_01967	8.03e-81	ymzB	-	-	-	-	-	-	-
CIGDHHLC_01968	6.55e-208	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
CIGDHHLC_01969	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
CIGDHHLC_01971	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
CIGDHHLC_01972	1.03e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
CIGDHHLC_01973	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
CIGDHHLC_01974	2.45e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
CIGDHHLC_01976	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
CIGDHHLC_01977	3.95e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CIGDHHLC_01978	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
CIGDHHLC_01979	1.63e-31	-	-	-	-	-	-	-	-
CIGDHHLC_01980	1.2e-30	ymzA	-	-	-	-	-	-	-
CIGDHHLC_01981	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
CIGDHHLC_01982	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIGDHHLC_01983	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIGDHHLC_01984	2.24e-141	-	-	-	-	-	-	-	-
CIGDHHLC_01985	1.16e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
CIGDHHLC_01986	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
CIGDHHLC_01987	1.82e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CIGDHHLC_01988	1.37e-309	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
CIGDHHLC_01989	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
CIGDHHLC_01990	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CIGDHHLC_01991	3.69e-32	-	-	-	-	-	-	-	-
CIGDHHLC_01992	1.68e-53	-	-	-	-	-	-	-	-
CIGDHHLC_01993	4.6e-309	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
CIGDHHLC_01995	1.68e-13	-	-	-	-	-	-	-	-
CIGDHHLC_01997	1.46e-105	-	-	-	-	-	-	-	-
CIGDHHLC_01998	4.13e-51	-	-	-	-	-	-	-	-
CIGDHHLC_01999	4.13e-116	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
CIGDHHLC_02000	9.3e-51	ynaC	-	-	-	-	-	-	-
CIGDHHLC_02001	3.65e-81	ynaC	-	-	-	-	-	-	-
CIGDHHLC_02002	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
CIGDHHLC_02003	2.61e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
CIGDHHLC_02004	8.3e-126	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CIGDHHLC_02006	3.24e-93	-	-	-	S	-	-	-	CAAX protease self-immunity
CIGDHHLC_02007	2.38e-11	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
CIGDHHLC_02008	8.64e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
CIGDHHLC_02009	1.6e-08	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
CIGDHHLC_02010	1.9e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
CIGDHHLC_02011	2.77e-19	ynaF	-	-	-	-	-	-	-
CIGDHHLC_02012	2.81e-106	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
CIGDHHLC_02013	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
CIGDHHLC_02014	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
CIGDHHLC_02015	6.82e-273	xylR	-	-	GK	-	-	-	ROK family
CIGDHHLC_02016	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
CIGDHHLC_02017	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
CIGDHHLC_02018	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
CIGDHHLC_02019	7.18e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
CIGDHHLC_02020	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CIGDHHLC_02021	4.34e-281	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CIGDHHLC_02023	1.22e-101	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
CIGDHHLC_02024	7.54e-22	-	-	-	-	-	-	-	-
CIGDHHLC_02027	7.89e-210	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CIGDHHLC_02029	2.43e-162	-	-	-	S	-	-	-	Domain of unknown function, YrpD
CIGDHHLC_02032	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
CIGDHHLC_02033	8.92e-96	-	-	-	-	-	-	-	-
CIGDHHLC_02034	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
CIGDHHLC_02037	9.36e-65	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
CIGDHHLC_02038	5.82e-184	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
CIGDHHLC_02039	5.45e-112	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
CIGDHHLC_02040	2.52e-196	yndG	-	-	S	-	-	-	DoxX-like family
CIGDHHLC_02041	2.87e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
CIGDHHLC_02042	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
CIGDHHLC_02045	6.31e-173	yndL	-	-	S	-	-	-	Replication protein
CIGDHHLC_02046	3.11e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
CIGDHHLC_02047	5.34e-97	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
CIGDHHLC_02048	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CIGDHHLC_02049	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
CIGDHHLC_02050	5.4e-143	yneB	-	-	L	-	-	-	resolvase
CIGDHHLC_02051	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
CIGDHHLC_02052	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CIGDHHLC_02053	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
CIGDHHLC_02054	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
CIGDHHLC_02055	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
CIGDHHLC_02056	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
CIGDHHLC_02057	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
CIGDHHLC_02058	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
CIGDHHLC_02059	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_02060	3.26e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_02061	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
CIGDHHLC_02062	7.02e-86	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
CIGDHHLC_02063	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
CIGDHHLC_02064	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
CIGDHHLC_02065	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CIGDHHLC_02066	8.82e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CIGDHHLC_02067	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
CIGDHHLC_02069	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
CIGDHHLC_02070	1.15e-94	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
CIGDHHLC_02071	3.3e-71	yneQ	-	-	-	-	-	-	-
CIGDHHLC_02072	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
CIGDHHLC_02073	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CIGDHHLC_02074	1.72e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
CIGDHHLC_02075	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIGDHHLC_02076	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIGDHHLC_02077	1.82e-18	-	-	-	-	-	-	-	-
CIGDHHLC_02078	8.74e-75	ynfC	-	-	-	-	-	-	-
CIGDHHLC_02079	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
CIGDHHLC_02080	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
CIGDHHLC_02082	1.32e-223	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
CIGDHHLC_02083	1.89e-31	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
CIGDHHLC_02084	5.7e-309	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
CIGDHHLC_02085	8.44e-31	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
CIGDHHLC_02086	1.36e-100	yngA	-	-	S	-	-	-	membrane
CIGDHHLC_02087	1.07e-207	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
CIGDHHLC_02088	1.16e-133	yngC	-	-	S	-	-	-	membrane-associated protein
CIGDHHLC_02089	1.74e-294	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
CIGDHHLC_02090	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CIGDHHLC_02091	4.96e-174	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
CIGDHHLC_02092	1.12e-210	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
CIGDHHLC_02093	7.15e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
CIGDHHLC_02094	5.62e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
CIGDHHLC_02095	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CIGDHHLC_02096	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
CIGDHHLC_02097	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
CIGDHHLC_02098	1.01e-82	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
CIGDHHLC_02099	7.8e-49	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
CIGDHHLC_02100	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
CIGDHHLC_02101	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIGDHHLC_02102	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
CIGDHHLC_02103	1.92e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
CIGDHHLC_02104	1.14e-311	yoeA	-	-	V	-	-	-	MATE efflux family protein
CIGDHHLC_02105	8.34e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
CIGDHHLC_02107	1.14e-124	-	-	-	L	-	-	-	Integrase
CIGDHHLC_02108	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
CIGDHHLC_02109	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
CIGDHHLC_02110	4.34e-201	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_02111	4.18e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CIGDHHLC_02112	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
CIGDHHLC_02113	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
CIGDHHLC_02114	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_02115	2.05e-173	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CIGDHHLC_02116	3.43e-100	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIGDHHLC_02117	1.07e-54	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIGDHHLC_02118	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
CIGDHHLC_02119	3.77e-158	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_02120	8.07e-53	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
CIGDHHLC_02121	7.05e-172	yoxB	-	-	-	-	-	-	-
CIGDHHLC_02122	2.31e-122	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CIGDHHLC_02123	6.24e-168	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CIGDHHLC_02124	2.92e-120	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CIGDHHLC_02125	7.41e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CIGDHHLC_02126	8.15e-105	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIGDHHLC_02127	2.24e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
CIGDHHLC_02128	2.23e-112	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
CIGDHHLC_02129	7.71e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
CIGDHHLC_02130	0.0	-	-	-	I	-	-	-	PLD-like domain
CIGDHHLC_02131	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
CIGDHHLC_02132	1.38e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
CIGDHHLC_02133	9.73e-194	-	-	-	S	-	-	-	membrane
CIGDHHLC_02134	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
CIGDHHLC_02135	4.34e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
CIGDHHLC_02136	1e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
CIGDHHLC_02137	5.84e-105	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
CIGDHHLC_02138	3.72e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
CIGDHHLC_02140	7.51e-205	-	-	-	P	-	-	-	Catalase
CIGDHHLC_02141	2.56e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
CIGDHHLC_02142	2.28e-13	-	-	-	S	-	-	-	TIGRFAM germination protein, Ger(x)C family
CIGDHHLC_02143	5.92e-194	-	-	-	EG	-	-	-	Spore germination protein
CIGDHHLC_02144	5.09e-42	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
CIGDHHLC_02145	2.2e-100	-	-	-	-	-	-	-	-
CIGDHHLC_02146	2.89e-25	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
CIGDHHLC_02147	5.32e-60	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
CIGDHHLC_02148	1.88e-19	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
CIGDHHLC_02149	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
CIGDHHLC_02150	3.56e-169	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
CIGDHHLC_02151	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
CIGDHHLC_02152	1.79e-66	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
CIGDHHLC_02153	2.87e-119	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
CIGDHHLC_02154	2.28e-67	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
CIGDHHLC_02156	3.1e-291	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
CIGDHHLC_02159	2.01e-108	-	-	-	-	-	-	-	-
CIGDHHLC_02160	5.78e-215	yoaR	-	-	V	-	-	-	vancomycin resistance protein
CIGDHHLC_02161	3.22e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
CIGDHHLC_02162	7e-40	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_02163	5.46e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
CIGDHHLC_02164	1.35e-202	yoaU	-	-	K	-	-	-	LysR substrate binding domain
CIGDHHLC_02165	3.7e-201	yoaV	-	-	EG	-	-	-	EamA-like transporter family
CIGDHHLC_02166	1.89e-100	yoaW	-	-	-	-	-	-	-
CIGDHHLC_02167	4.88e-147	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
CIGDHHLC_02168	8.51e-214	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
CIGDHHLC_02171	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
CIGDHHLC_02172	2.62e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
CIGDHHLC_02173	2.11e-49	-	-	-	S	-	-	-	TM2 domain
CIGDHHLC_02174	1.73e-70	-	-	-	K	-	-	-	Helix-turn-helix
CIGDHHLC_02177	1.45e-38	-	-	-	-	-	-	-	-
CIGDHHLC_02179	6.98e-279	-	-	-	L	-	-	-	Transposase
CIGDHHLC_02180	4.78e-152	-	-	-	L	-	-	-	Bacterial dnaA protein
CIGDHHLC_02183	0.0	-	-	-	V	-	-	-	Beta-lactamase
CIGDHHLC_02185	3.11e-12	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
CIGDHHLC_02187	4.82e-69	ynaF	-	-	-	-	-	-	-
CIGDHHLC_02188	4.58e-133	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
CIGDHHLC_02189	4.01e-36	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
CIGDHHLC_02190	4.98e-106	yoaW	-	-	-	-	-	-	-
CIGDHHLC_02191	3.46e-10	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
CIGDHHLC_02192	7.66e-99	-	-	-	-	-	-	-	-
CIGDHHLC_02193	3.2e-59	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
CIGDHHLC_02194	4.46e-23	-	-	-	-	-	-	-	-
CIGDHHLC_02196	1.57e-121	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
CIGDHHLC_02198	3.91e-52	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CIGDHHLC_02199	0.000751	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
CIGDHHLC_02200	4.01e-33	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
CIGDHHLC_02201	2.14e-17	-	-	-	Q	-	-	-	methyltransferase
CIGDHHLC_02203	1.91e-301	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
CIGDHHLC_02204	1.36e-37	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CIGDHHLC_02205	2.02e-48	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CIGDHHLC_02206	4.84e-85	-	-	-	S	-	-	-	damaged DNA binding
CIGDHHLC_02207	2.34e-14	-	-	-	S	-	-	-	YolD-like protein
CIGDHHLC_02210	1.06e-127	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CIGDHHLC_02211	7.01e-129	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
CIGDHHLC_02212	3.18e-101	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
CIGDHHLC_02213	1.35e-111	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
CIGDHHLC_02214	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CIGDHHLC_02215	2.8e-132	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
CIGDHHLC_02216	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
CIGDHHLC_02217	9e-72	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
CIGDHHLC_02218	4.89e-173	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CIGDHHLC_02219	2.81e-178	-	-	-	J	-	-	-	FR47-like protein
CIGDHHLC_02220	6.23e-127	yobS	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_02221	1.29e-167	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
CIGDHHLC_02222	4.8e-111	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
CIGDHHLC_02223	1.73e-221	yobV	-	-	K	-	-	-	WYL domain
CIGDHHLC_02224	7.38e-121	yobW	-	-	-	-	-	-	-
CIGDHHLC_02225	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
CIGDHHLC_02226	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CIGDHHLC_02228	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_02229	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
CIGDHHLC_02230	8.69e-184	-	-	-	-	-	-	-	-
CIGDHHLC_02231	7.04e-118	yocC	-	-	-	-	-	-	-
CIGDHHLC_02232	1.41e-242	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
CIGDHHLC_02233	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
CIGDHHLC_02234	4.09e-251	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_02235	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CIGDHHLC_02236	6.78e-174	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
CIGDHHLC_02237	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
CIGDHHLC_02238	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CIGDHHLC_02239	2.87e-107	yocK	-	-	T	-	-	-	general stress protein
CIGDHHLC_02240	2.81e-55	yocL	-	-	-	-	-	-	-
CIGDHHLC_02241	3.93e-41	-	-	-	-	-	-	-	-
CIGDHHLC_02242	5.43e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CIGDHHLC_02243	2.94e-55	yozN	-	-	-	-	-	-	-
CIGDHHLC_02244	1.83e-49	yocN	-	-	-	-	-	-	-
CIGDHHLC_02245	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
CIGDHHLC_02246	1.91e-42	yozC	-	-	-	-	-	-	-
CIGDHHLC_02247	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CIGDHHLC_02248	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
CIGDHHLC_02249	1.3e-206	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
CIGDHHLC_02250	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CIGDHHLC_02251	5.48e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
CIGDHHLC_02252	1.05e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
CIGDHHLC_02253	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
CIGDHHLC_02254	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
CIGDHHLC_02255	7.38e-205	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
CIGDHHLC_02256	4.94e-140	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CIGDHHLC_02257	2.48e-262	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
CIGDHHLC_02258	3.12e-291	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
CIGDHHLC_02259	2.14e-141	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CIGDHHLC_02261	2.93e-313	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
CIGDHHLC_02262	2.91e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CIGDHHLC_02263	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
CIGDHHLC_02264	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
CIGDHHLC_02265	1.85e-58	-	-	-	-	-	-	-	-
CIGDHHLC_02266	6.68e-207	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
CIGDHHLC_02267	8.34e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
CIGDHHLC_02268	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_02270	1.13e-13	-	-	-	-	-	-	-	-
CIGDHHLC_02271	3.6e-287	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
CIGDHHLC_02272	5.64e-84	iolK	-	-	S	-	-	-	tautomerase
CIGDHHLC_02273	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
CIGDHHLC_02274	1.92e-140	yodC	-	-	C	-	-	-	nitroreductase
CIGDHHLC_02275	2.17e-145	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
CIGDHHLC_02276	5.61e-222	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
CIGDHHLC_02277	3.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
CIGDHHLC_02278	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CIGDHHLC_02279	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
CIGDHHLC_02280	3.03e-166	yodH	-	-	Q	-	-	-	Methyltransferase
CIGDHHLC_02281	2.81e-40	yodI	-	-	-	-	-	-	-
CIGDHHLC_02282	7.71e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
CIGDHHLC_02283	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
CIGDHHLC_02284	2.08e-12	-	-	-	-	-	-	-	-
CIGDHHLC_02285	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
CIGDHHLC_02286	5.26e-134	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
CIGDHHLC_02287	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
CIGDHHLC_02289	7.44e-159	yodN	-	-	-	-	-	-	-
CIGDHHLC_02290	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
CIGDHHLC_02291	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
CIGDHHLC_02292	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
CIGDHHLC_02293	3.56e-195	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
CIGDHHLC_02294	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
CIGDHHLC_02295	3.66e-78	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CIGDHHLC_02296	1.15e-58	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CIGDHHLC_02298	3.28e-315	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CIGDHHLC_02300	1.97e-184	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
CIGDHHLC_02301	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
CIGDHHLC_02302	1.76e-58	cgeC	-	-	-	ko:K06321	-	ko00000	-
CIGDHHLC_02303	3.62e-82	cgeA	-	-	-	ko:K06319	-	ko00000	-
CIGDHHLC_02304	4.45e-226	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
CIGDHHLC_02305	1.34e-278	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
CIGDHHLC_02306	4.5e-155	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
CIGDHHLC_02307	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
CIGDHHLC_02308	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIGDHHLC_02309	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
CIGDHHLC_02310	1.65e-288	mepA	-	-	V	-	-	-	MATE efflux family protein
CIGDHHLC_02311	1.24e-39	ypmT	-	-	S	-	-	-	Uncharacterized ympT
CIGDHHLC_02312	4.59e-127	ypmS	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_02313	2.58e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
CIGDHHLC_02314	1.24e-135	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
CIGDHHLC_02315	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
CIGDHHLC_02316	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CIGDHHLC_02317	5.47e-234	yplP	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_02318	6.6e-142	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
CIGDHHLC_02319	4.7e-143	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CIGDHHLC_02320	7.88e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CIGDHHLC_02321	1.8e-120	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
CIGDHHLC_02322	2.01e-147	ypjP	-	-	S	-	-	-	YpjP-like protein
CIGDHHLC_02323	5.05e-186	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
CIGDHHLC_02324	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
CIGDHHLC_02325	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
CIGDHHLC_02326	8.52e-206	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
CIGDHHLC_02327	7.22e-142	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
CIGDHHLC_02328	5.2e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
CIGDHHLC_02329	1.01e-223	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CIGDHHLC_02330	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
CIGDHHLC_02331	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
CIGDHHLC_02332	1.17e-22	degR	-	-	-	-	-	-	-
CIGDHHLC_02333	1.05e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
CIGDHHLC_02334	7.99e-41	ypeQ	-	-	S	-	-	-	Zinc-finger
CIGDHHLC_02335	1.56e-160	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
CIGDHHLC_02336	6.59e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CIGDHHLC_02337	1.27e-86	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
CIGDHHLC_02338	2.59e-05	-	-	-	-	ko:K06429	-	ko00000	-
CIGDHHLC_02339	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
CIGDHHLC_02340	1.08e-11	-	-	-	-	-	-	-	-
CIGDHHLC_02341	1.66e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
CIGDHHLC_02342	0.0	ypbR	-	-	S	-	-	-	Dynamin family
CIGDHHLC_02343	1.36e-112	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
CIGDHHLC_02344	4.08e-41	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
CIGDHHLC_02345	1.49e-201	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
CIGDHHLC_02346	8.61e-292	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
CIGDHHLC_02347	9.13e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CIGDHHLC_02348	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CIGDHHLC_02349	2.36e-223	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
CIGDHHLC_02350	5.97e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
CIGDHHLC_02351	1.15e-236	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
CIGDHHLC_02352	2.24e-237	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
CIGDHHLC_02353	7.26e-204	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CIGDHHLC_02354	3.12e-174	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_02355	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
CIGDHHLC_02357	1.16e-285	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
CIGDHHLC_02358	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CIGDHHLC_02359	1.39e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
CIGDHHLC_02360	2.81e-298	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
CIGDHHLC_02361	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
CIGDHHLC_02362	2.59e-110	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
CIGDHHLC_02363	2.41e-92	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CIGDHHLC_02364	8.36e-66	yppG	-	-	S	-	-	-	YppG-like protein
CIGDHHLC_02365	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
CIGDHHLC_02366	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
CIGDHHLC_02369	2.52e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
CIGDHHLC_02370	1.3e-149	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CIGDHHLC_02371	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
CIGDHHLC_02372	1.43e-121	ypoC	-	-	-	-	-	-	-
CIGDHHLC_02373	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CIGDHHLC_02374	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
CIGDHHLC_02375	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
CIGDHHLC_02376	4.37e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
CIGDHHLC_02377	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_02378	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
CIGDHHLC_02379	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
CIGDHHLC_02380	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CIGDHHLC_02381	1.57e-199	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CIGDHHLC_02382	9.79e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
CIGDHHLC_02383	6.91e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CIGDHHLC_02384	1.83e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CIGDHHLC_02385	2.45e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
CIGDHHLC_02386	2.21e-165	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
CIGDHHLC_02387	2.52e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
CIGDHHLC_02388	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CIGDHHLC_02389	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
CIGDHHLC_02390	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
CIGDHHLC_02391	6.56e-181	ypjB	-	-	S	-	-	-	sporulation protein
CIGDHHLC_02392	1.15e-125	ypjA	-	-	S	-	-	-	membrane
CIGDHHLC_02393	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
CIGDHHLC_02394	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
CIGDHHLC_02395	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
CIGDHHLC_02396	5.55e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
CIGDHHLC_02397	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
CIGDHHLC_02398	3.56e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
CIGDHHLC_02399	9.49e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CIGDHHLC_02400	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
CIGDHHLC_02401	2.6e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CIGDHHLC_02402	3.14e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CIGDHHLC_02403	1.09e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CIGDHHLC_02404	2.6e-149	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
CIGDHHLC_02405	2.95e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
CIGDHHLC_02406	2.37e-227	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CIGDHHLC_02407	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CIGDHHLC_02408	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
CIGDHHLC_02409	3.86e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CIGDHHLC_02410	5.88e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CIGDHHLC_02411	3.69e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
CIGDHHLC_02412	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CIGDHHLC_02413	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CIGDHHLC_02414	5.46e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CIGDHHLC_02415	7.17e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
CIGDHHLC_02416	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
CIGDHHLC_02417	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
CIGDHHLC_02419	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_02420	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CIGDHHLC_02421	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CIGDHHLC_02422	8.71e-176	yphF	-	-	-	-	-	-	-
CIGDHHLC_02423	1.43e-26	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
CIGDHHLC_02424	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
CIGDHHLC_02425	5.72e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
CIGDHHLC_02426	1.19e-37	ypzH	-	-	-	-	-	-	-
CIGDHHLC_02427	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
CIGDHHLC_02428	1.11e-133	yphA	-	-	-	-	-	-	-
CIGDHHLC_02429	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
CIGDHHLC_02430	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_02431	3.26e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_02432	2.21e-233	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CIGDHHLC_02433	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
CIGDHHLC_02434	5.8e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
CIGDHHLC_02435	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
CIGDHHLC_02436	2.02e-138	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
CIGDHHLC_02437	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
CIGDHHLC_02438	1.99e-207	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
CIGDHHLC_02439	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
CIGDHHLC_02440	2.51e-222	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
CIGDHHLC_02441	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
CIGDHHLC_02442	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CIGDHHLC_02443	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
CIGDHHLC_02444	4.08e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
CIGDHHLC_02445	5.04e-148	ypbE	-	-	M	-	-	-	Lysin motif
CIGDHHLC_02446	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
CIGDHHLC_02447	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
CIGDHHLC_02448	3.14e-255	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
CIGDHHLC_02449	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
CIGDHHLC_02450	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CIGDHHLC_02451	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIGDHHLC_02452	9.27e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CIGDHHLC_02453	2.96e-135	rsiX	-	-	-	-	-	-	-
CIGDHHLC_02454	8.11e-17	rsiX	-	-	-	-	-	-	-
CIGDHHLC_02455	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIGDHHLC_02456	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_02457	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_02458	1.56e-277	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
CIGDHHLC_02459	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
CIGDHHLC_02460	8.71e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
CIGDHHLC_02461	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CIGDHHLC_02462	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
CIGDHHLC_02463	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
CIGDHHLC_02464	1.18e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CIGDHHLC_02465	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
CIGDHHLC_02466	9.54e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CIGDHHLC_02467	3.82e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CIGDHHLC_02468	1.4e-117	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
CIGDHHLC_02469	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIGDHHLC_02470	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CIGDHHLC_02471	1.04e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CIGDHHLC_02472	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
CIGDHHLC_02473	3.42e-259	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CIGDHHLC_02474	5.98e-72	ypuD	-	-	-	-	-	-	-
CIGDHHLC_02475	3.63e-120	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CIGDHHLC_02477	7.41e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
CIGDHHLC_02479	5.68e-58	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CIGDHHLC_02481	3.82e-37	-	-	-	-	-	-	-	-
CIGDHHLC_02482	1.22e-29	-	-	-	L	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
CIGDHHLC_02484	8.16e-77	-	-	-	O	-	-	-	Papain family cysteine protease
CIGDHHLC_02485	1.73e-13	-	-	-	-	-	-	-	-
CIGDHHLC_02486	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
CIGDHHLC_02487	8.22e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
CIGDHHLC_02488	7.74e-301	-	-	-	I	-	-	-	Pfam Lipase (class 3)
CIGDHHLC_02489	9.96e-22	-	-	-	-	-	-	-	-
CIGDHHLC_02491	7.27e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
CIGDHHLC_02496	8.64e-97	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CIGDHHLC_02497	4.66e-41	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CIGDHHLC_02498	3.12e-192	ypuA	-	-	S	-	-	-	Secreted protein
CIGDHHLC_02499	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CIGDHHLC_02500	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
CIGDHHLC_02501	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
CIGDHHLC_02502	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
CIGDHHLC_02503	8.55e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
CIGDHHLC_02504	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
CIGDHHLC_02505	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
CIGDHHLC_02506	4.7e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
CIGDHHLC_02507	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CIGDHHLC_02508	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
CIGDHHLC_02509	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
CIGDHHLC_02510	8.27e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CIGDHHLC_02511	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CIGDHHLC_02512	3.77e-291	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CIGDHHLC_02513	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
CIGDHHLC_02514	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
CIGDHHLC_02515	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
CIGDHHLC_02516	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
CIGDHHLC_02517	1.47e-41	yqkK	-	-	-	-	-	-	-
CIGDHHLC_02518	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
CIGDHHLC_02519	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
CIGDHHLC_02520	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
CIGDHHLC_02521	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
CIGDHHLC_02522	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_02523	1.45e-280	yqxK	-	-	L	-	-	-	DNA helicase
CIGDHHLC_02524	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
CIGDHHLC_02525	6.19e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
CIGDHHLC_02526	2.09e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
CIGDHHLC_02527	8.04e-27	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
CIGDHHLC_02528	4.61e-222	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
CIGDHHLC_02529	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
CIGDHHLC_02530	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
CIGDHHLC_02531	3.23e-248	yqkA	-	-	K	-	-	-	GrpB protein
CIGDHHLC_02532	1.52e-76	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
CIGDHHLC_02533	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
CIGDHHLC_02534	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
CIGDHHLC_02535	1.46e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CIGDHHLC_02537	4.23e-287	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
CIGDHHLC_02539	2.21e-94	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIGDHHLC_02540	2.69e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
CIGDHHLC_02541	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
CIGDHHLC_02542	6.89e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_02543	1.56e-227	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
CIGDHHLC_02544	1.96e-189	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIGDHHLC_02545	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_02547	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
CIGDHHLC_02548	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
CIGDHHLC_02549	3.17e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CIGDHHLC_02550	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CIGDHHLC_02551	2.2e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CIGDHHLC_02552	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CIGDHHLC_02553	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CIGDHHLC_02554	1.06e-298	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CIGDHHLC_02555	4.35e-32	yqzJ	-	-	-	-	-	-	-
CIGDHHLC_02556	1.47e-178	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIGDHHLC_02557	1.57e-177	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
CIGDHHLC_02558	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
CIGDHHLC_02559	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CIGDHHLC_02560	5.45e-94	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
CIGDHHLC_02561	9.84e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_02562	1.73e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
CIGDHHLC_02563	1.49e-165	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
CIGDHHLC_02564	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
CIGDHHLC_02565	1.18e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
CIGDHHLC_02566	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
CIGDHHLC_02567	4.23e-214	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CIGDHHLC_02568	1.79e-266	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_02569	4.31e-193	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
CIGDHHLC_02570	3.77e-288	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CIGDHHLC_02571	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CIGDHHLC_02572	1.11e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CIGDHHLC_02573	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CIGDHHLC_02574	3.39e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
CIGDHHLC_02575	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
CIGDHHLC_02576	1.18e-196	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
CIGDHHLC_02577	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
CIGDHHLC_02578	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
CIGDHHLC_02579	7.23e-208	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CIGDHHLC_02580	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
CIGDHHLC_02581	3.9e-266	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
CIGDHHLC_02582	2.01e-267	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
CIGDHHLC_02583	1.19e-199	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
CIGDHHLC_02584	2.59e-277	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
CIGDHHLC_02585	7.42e-172	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
CIGDHHLC_02586	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
CIGDHHLC_02587	4.74e-37	-	-	-	-	-	-	-	-
CIGDHHLC_02588	3.28e-270	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
CIGDHHLC_02590	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
CIGDHHLC_02591	2.54e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
CIGDHHLC_02592	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
CIGDHHLC_02593	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CIGDHHLC_02594	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
CIGDHHLC_02595	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CIGDHHLC_02596	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CIGDHHLC_02597	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIGDHHLC_02598	1.02e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIGDHHLC_02599	1.24e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CIGDHHLC_02600	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CIGDHHLC_02601	9.55e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_02602	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CIGDHHLC_02603	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CIGDHHLC_02604	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
CIGDHHLC_02605	7.6e-149	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
CIGDHHLC_02606	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
CIGDHHLC_02607	3.11e-256	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
CIGDHHLC_02608	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
CIGDHHLC_02609	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
CIGDHHLC_02610	3.29e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
CIGDHHLC_02611	1.22e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
CIGDHHLC_02612	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
CIGDHHLC_02613	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CIGDHHLC_02614	3.65e-250	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
CIGDHHLC_02615	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
CIGDHHLC_02616	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
CIGDHHLC_02617	1.48e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
CIGDHHLC_02618	5.18e-81	yqhP	-	-	-	-	-	-	-
CIGDHHLC_02619	1.41e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
CIGDHHLC_02620	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
CIGDHHLC_02621	2.63e-203	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
CIGDHHLC_02622	2.51e-81	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
CIGDHHLC_02623	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CIGDHHLC_02624	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CIGDHHLC_02625	7.79e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
CIGDHHLC_02626	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
CIGDHHLC_02627	1.52e-195	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
CIGDHHLC_02628	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
CIGDHHLC_02629	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
CIGDHHLC_02630	3.67e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
CIGDHHLC_02631	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
CIGDHHLC_02632	9.33e-155	yqxM	-	-	-	ko:K19433	-	ko00000	-
CIGDHHLC_02633	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
CIGDHHLC_02634	2.84e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
CIGDHHLC_02635	7.63e-57	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
CIGDHHLC_02636	4.1e-60	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
CIGDHHLC_02637	3.45e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
CIGDHHLC_02638	1.11e-91	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
CIGDHHLC_02639	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
CIGDHHLC_02640	7.16e-218	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
CIGDHHLC_02641	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CIGDHHLC_02642	3.73e-09	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
CIGDHHLC_02643	8.73e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
CIGDHHLC_02644	2.01e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
CIGDHHLC_02645	4.82e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CIGDHHLC_02647	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
CIGDHHLC_02648	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
CIGDHHLC_02650	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_02651	1.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
CIGDHHLC_02652	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
CIGDHHLC_02653	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
CIGDHHLC_02654	2.69e-256	yqgU	-	-	-	-	-	-	-
CIGDHHLC_02655	3.55e-282	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
CIGDHHLC_02656	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
CIGDHHLC_02657	3.28e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
CIGDHHLC_02658	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
CIGDHHLC_02659	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
CIGDHHLC_02660	3.38e-14	yqgO	-	-	-	-	-	-	-
CIGDHHLC_02661	4.62e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CIGDHHLC_02662	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CIGDHHLC_02663	1.94e-248	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
CIGDHHLC_02665	2.81e-67	yqzD	-	-	-	-	-	-	-
CIGDHHLC_02666	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
CIGDHHLC_02667	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIGDHHLC_02668	1.14e-188	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIGDHHLC_02669	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
CIGDHHLC_02670	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CIGDHHLC_02671	2.61e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
CIGDHHLC_02672	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
CIGDHHLC_02673	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
CIGDHHLC_02674	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
CIGDHHLC_02675	2.36e-100	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
CIGDHHLC_02676	1.12e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
CIGDHHLC_02677	1.35e-61	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
CIGDHHLC_02678	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CIGDHHLC_02679	2.38e-80	yqfX	-	-	S	-	-	-	membrane
CIGDHHLC_02680	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
CIGDHHLC_02681	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
CIGDHHLC_02682	2.21e-198	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
CIGDHHLC_02683	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
CIGDHHLC_02684	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CIGDHHLC_02685	1.09e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CIGDHHLC_02686	1.05e-48	yqfQ	-	-	S	-	-	-	YqfQ-like protein
CIGDHHLC_02687	1.01e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CIGDHHLC_02688	7.29e-267	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CIGDHHLC_02689	1.98e-149	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
CIGDHHLC_02690	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
CIGDHHLC_02691	2.29e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CIGDHHLC_02692	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CIGDHHLC_02693	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
CIGDHHLC_02694	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CIGDHHLC_02695	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
CIGDHHLC_02696	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
CIGDHHLC_02697	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
CIGDHHLC_02698	2.14e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
CIGDHHLC_02699	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
CIGDHHLC_02700	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CIGDHHLC_02701	5.52e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CIGDHHLC_02702	3.34e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
CIGDHHLC_02703	1.75e-105	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CIGDHHLC_02704	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
CIGDHHLC_02706	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
CIGDHHLC_02707	8.52e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
CIGDHHLC_02708	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
CIGDHHLC_02709	2.23e-56	yqfB	-	-	-	-	-	-	-
CIGDHHLC_02710	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
CIGDHHLC_02711	3.78e-290	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
CIGDHHLC_02712	4.53e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
CIGDHHLC_02713	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
CIGDHHLC_02714	8.29e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
CIGDHHLC_02715	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
CIGDHHLC_02716	6.85e-179	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CIGDHHLC_02717	2.29e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
CIGDHHLC_02718	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CIGDHHLC_02719	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
CIGDHHLC_02720	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CIGDHHLC_02721	5.74e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CIGDHHLC_02722	5.86e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
CIGDHHLC_02723	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CIGDHHLC_02724	7.06e-70	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
CIGDHHLC_02725	2.73e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
CIGDHHLC_02726	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CIGDHHLC_02727	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
CIGDHHLC_02728	4.06e-244	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
CIGDHHLC_02729	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
CIGDHHLC_02730	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
CIGDHHLC_02731	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
CIGDHHLC_02732	3.69e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
CIGDHHLC_02733	4.46e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIGDHHLC_02734	7.73e-176	yqeM	-	-	Q	-	-	-	Methyltransferase
CIGDHHLC_02735	1.14e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CIGDHHLC_02736	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
CIGDHHLC_02737	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CIGDHHLC_02738	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
CIGDHHLC_02739	8.1e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CIGDHHLC_02740	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CIGDHHLC_02741	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
CIGDHHLC_02743	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
CIGDHHLC_02744	2.3e-174	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
CIGDHHLC_02745	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
CIGDHHLC_02746	7.31e-215	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
CIGDHHLC_02747	7.4e-168	-	-	-	-	-	-	-	-
CIGDHHLC_02748	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
CIGDHHLC_02749	7.53e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CIGDHHLC_02750	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CIGDHHLC_02751	1.14e-197	yybE	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_02752	8.28e-87	-	-	-	K	-	-	-	Glyoxalase bleomycin resistance protein dioxygenase
CIGDHHLC_02754	4.93e-266	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
CIGDHHLC_02755	3.2e-13	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CIGDHHLC_02756	1.72e-221	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
CIGDHHLC_02757	3.4e-49	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
CIGDHHLC_02759	5.52e-37	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
CIGDHHLC_02760	1.1e-20	-	-	-	S	-	-	-	SMI1 / KNR4 family
CIGDHHLC_02761	5.24e-60	-	-	-	-	-	-	-	-
CIGDHHLC_02765	5.5e-37	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
CIGDHHLC_02766	1.89e-40	-	-	-	-	-	-	-	-
CIGDHHLC_02767	6.98e-279	-	-	-	L	-	-	-	Transposase
CIGDHHLC_02768	4.78e-152	-	-	-	L	-	-	-	Bacterial dnaA protein
CIGDHHLC_02770	5.08e-26	xkdM	-	-	S	-	-	-	Phage tail tube protein
CIGDHHLC_02771	2.43e-14	-	-	-	-	-	-	-	-
CIGDHHLC_02774	7.44e-05	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
CIGDHHLC_02777	1.24e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CIGDHHLC_02778	1.08e-268	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_02779	7.23e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
CIGDHHLC_02780	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
CIGDHHLC_02781	1.02e-297	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
CIGDHHLC_02782	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
CIGDHHLC_02783	3.17e-212	yrdR	-	-	EG	-	-	-	EamA-like transporter family
CIGDHHLC_02784	1.4e-203	-	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_02785	1.23e-253	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
CIGDHHLC_02786	9.05e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
CIGDHHLC_02787	1.18e-252	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
CIGDHHLC_02789	6.48e-288	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CIGDHHLC_02790	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
CIGDHHLC_02791	9.34e-176	azlC	-	-	E	-	-	-	AzlC protein
CIGDHHLC_02792	4.82e-103	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
CIGDHHLC_02793	2.76e-55	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
CIGDHHLC_02794	1.74e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
CIGDHHLC_02795	3.24e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
CIGDHHLC_02796	2.01e-118	yrdA	-	-	S	-	-	-	DinB family
CIGDHHLC_02797	3.9e-210	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
CIGDHHLC_02798	2.45e-245	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
CIGDHHLC_02799	9.78e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
CIGDHHLC_02800	2.39e-162	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
CIGDHHLC_02802	4.22e-164	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
CIGDHHLC_02803	2.5e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIGDHHLC_02804	4.9e-239	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
CIGDHHLC_02805	2.2e-193	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
CIGDHHLC_02806	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CIGDHHLC_02807	1.19e-191	-	-	-	S	-	-	-	Alpha beta hydrolase
CIGDHHLC_02808	6.56e-81	-	-	-	T	-	-	-	sh3 domain protein
CIGDHHLC_02809	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
CIGDHHLC_02810	6.62e-87	-	-	-	E	-	-	-	Glyoxalase-like domain
CIGDHHLC_02811	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
CIGDHHLC_02812	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
CIGDHHLC_02813	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CIGDHHLC_02814	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
CIGDHHLC_02815	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
CIGDHHLC_02816	1.83e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
CIGDHHLC_02817	1.76e-39	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
CIGDHHLC_02818	4.81e-253	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
CIGDHHLC_02819	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
CIGDHHLC_02820	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
CIGDHHLC_02821	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
CIGDHHLC_02822	1.75e-167	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
CIGDHHLC_02823	4.41e-106	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
CIGDHHLC_02824	4.41e-96	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CIGDHHLC_02825	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
CIGDHHLC_02826	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
CIGDHHLC_02827	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
CIGDHHLC_02828	3.41e-193	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
CIGDHHLC_02829	2.35e-112	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIGDHHLC_02830	3.51e-191	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
CIGDHHLC_02831	2.18e-84	oatA	-	-	I	-	-	-	Acyltransferase family
CIGDHHLC_02832	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
CIGDHHLC_02833	2.58e-58	yrhK	-	-	S	-	-	-	YrhK-like protein
CIGDHHLC_02834	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
CIGDHHLC_02835	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
CIGDHHLC_02836	4.3e-124	yrhH	-	-	Q	-	-	-	methyltransferase
CIGDHHLC_02837	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
CIGDHHLC_02839	1.13e-182	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
CIGDHHLC_02840	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
CIGDHHLC_02841	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
CIGDHHLC_02842	2.46e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
CIGDHHLC_02843	5.71e-48	yrhC	-	-	S	-	-	-	YrhC-like protein
CIGDHHLC_02844	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
CIGDHHLC_02845	1.66e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
CIGDHHLC_02846	3.26e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CIGDHHLC_02847	9.86e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
CIGDHHLC_02848	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
CIGDHHLC_02849	2.02e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
CIGDHHLC_02850	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
CIGDHHLC_02851	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIGDHHLC_02852	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
CIGDHHLC_02853	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
CIGDHHLC_02854	2.57e-221	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
CIGDHHLC_02855	6.92e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
CIGDHHLC_02856	6.17e-241	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CIGDHHLC_02857	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
CIGDHHLC_02858	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CIGDHHLC_02859	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
CIGDHHLC_02860	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CIGDHHLC_02861	1.25e-241	yrrI	-	-	S	-	-	-	AI-2E family transporter
CIGDHHLC_02862	2.21e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
CIGDHHLC_02863	3.93e-182	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
CIGDHHLC_02864	1.54e-137	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIGDHHLC_02865	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIGDHHLC_02866	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_02868	8.96e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
CIGDHHLC_02869	8.4e-42	yrzR	-	-	-	-	-	-	-
CIGDHHLC_02870	2.79e-105	yrrD	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_02871	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CIGDHHLC_02872	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
CIGDHHLC_02873	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CIGDHHLC_02874	2.56e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
CIGDHHLC_02875	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_02876	6.69e-301	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
CIGDHHLC_02877	2.29e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
CIGDHHLC_02878	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CIGDHHLC_02879	3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
CIGDHHLC_02881	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
CIGDHHLC_02882	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CIGDHHLC_02883	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CIGDHHLC_02884	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CIGDHHLC_02885	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
CIGDHHLC_02886	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
CIGDHHLC_02887	5.35e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
CIGDHHLC_02888	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CIGDHHLC_02889	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
CIGDHHLC_02890	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CIGDHHLC_02891	3.37e-142	yrbG	-	-	S	-	-	-	membrane
CIGDHHLC_02892	2.16e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
CIGDHHLC_02893	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
CIGDHHLC_02894	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CIGDHHLC_02895	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CIGDHHLC_02896	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
CIGDHHLC_02897	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CIGDHHLC_02898	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CIGDHHLC_02899	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
CIGDHHLC_02900	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
CIGDHHLC_02901	1.67e-247	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
CIGDHHLC_02902	1.91e-151	yrzF	-	-	T	-	-	-	serine threonine protein kinase
CIGDHHLC_02904	2.55e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
CIGDHHLC_02905	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
CIGDHHLC_02906	3.51e-164	yebC	-	-	K	-	-	-	transcriptional regulatory protein
CIGDHHLC_02907	5.13e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CIGDHHLC_02908	3.45e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
CIGDHHLC_02909	4.41e-270	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CIGDHHLC_02910	1.02e-201	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
CIGDHHLC_02911	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
CIGDHHLC_02912	1.17e-290	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
CIGDHHLC_02913	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
CIGDHHLC_02914	2.54e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
CIGDHHLC_02915	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
CIGDHHLC_02916	9.66e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CIGDHHLC_02917	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
CIGDHHLC_02918	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
CIGDHHLC_02919	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
CIGDHHLC_02920	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
CIGDHHLC_02921	1.52e-207	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
CIGDHHLC_02922	7.44e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
CIGDHHLC_02923	4.13e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
CIGDHHLC_02924	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CIGDHHLC_02925	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
CIGDHHLC_02926	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
CIGDHHLC_02927	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
CIGDHHLC_02928	2.4e-162	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
CIGDHHLC_02929	2.02e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
CIGDHHLC_02930	2.47e-210	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
CIGDHHLC_02931	1.28e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
CIGDHHLC_02932	6.38e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
CIGDHHLC_02933	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CIGDHHLC_02934	1.53e-35	-	-	-	-	-	-	-	-
CIGDHHLC_02935	2.39e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CIGDHHLC_02936	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
CIGDHHLC_02937	1.44e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
CIGDHHLC_02938	2.14e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
CIGDHHLC_02939	4.13e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
CIGDHHLC_02940	6.27e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CIGDHHLC_02941	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
CIGDHHLC_02942	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CIGDHHLC_02943	4.77e-116	ysxD	-	-	-	-	-	-	-
CIGDHHLC_02944	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
CIGDHHLC_02945	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CIGDHHLC_02946	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
CIGDHHLC_02947	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CIGDHHLC_02948	5.98e-285	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CIGDHHLC_02949	2.62e-238	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
CIGDHHLC_02950	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CIGDHHLC_02951	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CIGDHHLC_02952	2.04e-253	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CIGDHHLC_02953	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CIGDHHLC_02954	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CIGDHHLC_02955	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
CIGDHHLC_02956	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
CIGDHHLC_02958	3.28e-46	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
CIGDHHLC_02959	3.36e-181	ysnF	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_02960	3.26e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_02961	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_02962	3.84e-87	res	-	-	L	-	-	-	Resolvase, N terminal domain
CIGDHHLC_02963	6.97e-98	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
CIGDHHLC_02964	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
CIGDHHLC_02965	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
CIGDHHLC_02968	3.17e-170	-	-	-	L	-	-	-	Phage integrase family
CIGDHHLC_02970	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
CIGDHHLC_02971	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CIGDHHLC_02972	4.12e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CIGDHHLC_02973	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
CIGDHHLC_02974	7.22e-198	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
CIGDHHLC_02975	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIGDHHLC_02976	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_02977	1.26e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
CIGDHHLC_02978	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
CIGDHHLC_02979	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
CIGDHHLC_02980	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
CIGDHHLC_02981	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
CIGDHHLC_02982	1.13e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
CIGDHHLC_02983	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CIGDHHLC_02984	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CIGDHHLC_02985	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
CIGDHHLC_02987	5e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
CIGDHHLC_02988	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
CIGDHHLC_02989	5.17e-175	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
CIGDHHLC_02990	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_02991	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CIGDHHLC_02992	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
CIGDHHLC_02993	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CIGDHHLC_02994	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
CIGDHHLC_02995	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
CIGDHHLC_02996	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CIGDHHLC_02997	8.48e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIGDHHLC_02998	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIGDHHLC_02999	7.36e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CIGDHHLC_03000	7.68e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIGDHHLC_03001	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
CIGDHHLC_03002	3.19e-263	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
CIGDHHLC_03003	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
CIGDHHLC_03004	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
CIGDHHLC_03005	8.42e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
CIGDHHLC_03006	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
CIGDHHLC_03007	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
CIGDHHLC_03008	4.28e-190	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
CIGDHHLC_03009	7.9e-218	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
CIGDHHLC_03010	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
CIGDHHLC_03011	3.05e-281	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
CIGDHHLC_03012	2.52e-61	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
CIGDHHLC_03013	1.46e-87	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
CIGDHHLC_03014	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
CIGDHHLC_03015	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
CIGDHHLC_03016	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
CIGDHHLC_03017	4.56e-241	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
CIGDHHLC_03018	3.57e-261	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
CIGDHHLC_03019	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
CIGDHHLC_03020	3.65e-59	ysdA	-	-	S	-	-	-	Membrane
CIGDHHLC_03021	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CIGDHHLC_03022	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
CIGDHHLC_03023	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CIGDHHLC_03025	1.53e-149	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CIGDHHLC_03026	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CIGDHHLC_03027	1.96e-166	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
CIGDHHLC_03028	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_03029	1.98e-189	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
CIGDHHLC_03030	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIGDHHLC_03032	2e-204	ytxC	-	-	S	-	-	-	YtxC-like family
CIGDHHLC_03033	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
CIGDHHLC_03034	1.22e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
CIGDHHLC_03035	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
CIGDHHLC_03036	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CIGDHHLC_03037	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CIGDHHLC_03038	9.99e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CIGDHHLC_03039	1.15e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03040	1.6e-254	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
CIGDHHLC_03041	4.54e-205	ytbE	-	-	S	-	-	-	reductase
CIGDHHLC_03042	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03043	1.63e-125	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CIGDHHLC_03044	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
CIGDHHLC_03045	1.07e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CIGDHHLC_03046	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CIGDHHLC_03047	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
CIGDHHLC_03048	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_03049	6.01e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
CIGDHHLC_03050	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
CIGDHHLC_03051	3.2e-265	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
CIGDHHLC_03052	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03053	9.38e-95	ytwI	-	-	S	-	-	-	membrane
CIGDHHLC_03054	2.24e-244	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
CIGDHHLC_03055	2.71e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
CIGDHHLC_03056	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
CIGDHHLC_03057	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CIGDHHLC_03058	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CIGDHHLC_03059	5.1e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CIGDHHLC_03060	1.21e-286	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
CIGDHHLC_03061	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
CIGDHHLC_03062	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
CIGDHHLC_03063	5.12e-112	ytrI	-	-	-	-	-	-	-
CIGDHHLC_03064	1.15e-39	-	-	-	-	-	-	-	-
CIGDHHLC_03065	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
CIGDHHLC_03066	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
CIGDHHLC_03067	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
CIGDHHLC_03068	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
CIGDHHLC_03069	8.04e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_03071	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
CIGDHHLC_03072	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
CIGDHHLC_03073	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
CIGDHHLC_03074	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIGDHHLC_03075	6.26e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
CIGDHHLC_03076	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CIGDHHLC_03077	5.02e-90	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
CIGDHHLC_03078	6.29e-144	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
CIGDHHLC_03079	8.23e-112	yteJ	-	-	S	-	-	-	RDD family
CIGDHHLC_03080	3.25e-228	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
CIGDHHLC_03081	8.04e-188	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CIGDHHLC_03083	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03084	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
CIGDHHLC_03085	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CIGDHHLC_03086	5.88e-38	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
CIGDHHLC_03087	2.55e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CIGDHHLC_03088	1.59e-265	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
CIGDHHLC_03089	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CIGDHHLC_03090	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CIGDHHLC_03091	1.07e-197	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
CIGDHHLC_03092	9.83e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03093	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
CIGDHHLC_03094	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
CIGDHHLC_03095	5.43e-57	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
CIGDHHLC_03096	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CIGDHHLC_03098	5.31e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CIGDHHLC_03099	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CIGDHHLC_03100	3.46e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
CIGDHHLC_03101	1.45e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
CIGDHHLC_03102	2.58e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
CIGDHHLC_03103	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
CIGDHHLC_03104	1.18e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
CIGDHHLC_03105	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
CIGDHHLC_03106	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
CIGDHHLC_03107	6.39e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
CIGDHHLC_03108	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
CIGDHHLC_03109	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CIGDHHLC_03110	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
CIGDHHLC_03111	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CIGDHHLC_03112	7.25e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIGDHHLC_03113	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
CIGDHHLC_03114	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
CIGDHHLC_03115	4.89e-63	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
CIGDHHLC_03116	4.88e-29	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
CIGDHHLC_03117	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
CIGDHHLC_03118	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
CIGDHHLC_03119	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
CIGDHHLC_03120	3.05e-190	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
CIGDHHLC_03121	2.52e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CIGDHHLC_03122	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
CIGDHHLC_03123	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
CIGDHHLC_03124	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
CIGDHHLC_03125	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
CIGDHHLC_03126	9.92e-212	ytlQ	-	-	-	-	-	-	-
CIGDHHLC_03127	1.5e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CIGDHHLC_03128	3.22e-218	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
CIGDHHLC_03129	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
CIGDHHLC_03130	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
CIGDHHLC_03131	1.12e-252	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
CIGDHHLC_03132	8.04e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CIGDHHLC_03133	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
CIGDHHLC_03134	7.43e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CIGDHHLC_03135	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CIGDHHLC_03136	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
CIGDHHLC_03137	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
CIGDHHLC_03138	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
CIGDHHLC_03140	6.02e-315	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
CIGDHHLC_03141	9.64e-94	yteS	-	-	G	-	-	-	transport
CIGDHHLC_03142	8.3e-279	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
CIGDHHLC_03143	5.35e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
CIGDHHLC_03144	1.36e-202	ytdP	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03145	2.13e-75	ytdP	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03146	1.13e-165	ytdP	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03147	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
CIGDHHLC_03148	1.19e-190	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
CIGDHHLC_03149	2.21e-178	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
CIGDHHLC_03150	2.6e-278	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
CIGDHHLC_03151	2.64e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CIGDHHLC_03152	2.68e-159	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CIGDHHLC_03153	4.1e-272	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CIGDHHLC_03154	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
CIGDHHLC_03155	3.63e-151	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CIGDHHLC_03156	4.8e-221	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
CIGDHHLC_03157	4.37e-242	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_03158	7.92e-307	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIGDHHLC_03159	1.66e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIGDHHLC_03160	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
CIGDHHLC_03161	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
CIGDHHLC_03162	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
CIGDHHLC_03163	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
CIGDHHLC_03164	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
CIGDHHLC_03165	3.82e-183	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
CIGDHHLC_03166	1.21e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
CIGDHHLC_03167	5.71e-41	yttA	-	-	S	-	-	-	Pfam Transposase IS66
CIGDHHLC_03168	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
CIGDHHLC_03169	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_03170	4.53e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
CIGDHHLC_03171	2.23e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_03172	3.99e-296	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
CIGDHHLC_03173	5.88e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_03174	1.37e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
CIGDHHLC_03175	4.46e-211	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
CIGDHHLC_03176	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_03177	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
CIGDHHLC_03179	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
CIGDHHLC_03180	4.06e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
CIGDHHLC_03181	2.75e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
CIGDHHLC_03182	2.78e-275	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
CIGDHHLC_03183	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
CIGDHHLC_03184	5.88e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CIGDHHLC_03185	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
CIGDHHLC_03186	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
CIGDHHLC_03187	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CIGDHHLC_03188	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CIGDHHLC_03189	2.52e-50	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
CIGDHHLC_03190	9.48e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
CIGDHHLC_03191	7.95e-242	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
CIGDHHLC_03192	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CIGDHHLC_03193	1.09e-182	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CIGDHHLC_03194	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
CIGDHHLC_03195	1.52e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
CIGDHHLC_03196	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
CIGDHHLC_03198	4.78e-95	ytkA	-	-	S	-	-	-	YtkA-like
CIGDHHLC_03199	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CIGDHHLC_03200	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
CIGDHHLC_03201	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
CIGDHHLC_03202	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
CIGDHHLC_03203	1.64e-238	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
CIGDHHLC_03204	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
CIGDHHLC_03205	7.92e-193	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
CIGDHHLC_03206	5.85e-293	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CIGDHHLC_03207	1.5e-179	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CIGDHHLC_03208	3.23e-218	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CIGDHHLC_03209	1.43e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CIGDHHLC_03210	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CIGDHHLC_03211	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CIGDHHLC_03212	9.85e-197	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
CIGDHHLC_03213	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CIGDHHLC_03214	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
CIGDHHLC_03215	1.44e-167	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
CIGDHHLC_03216	5.69e-195	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
CIGDHHLC_03217	4.1e-310	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CIGDHHLC_03218	2.78e-224	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
CIGDHHLC_03219	7.32e-292	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
CIGDHHLC_03221	6.65e-261	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
CIGDHHLC_03222	1.61e-272	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
CIGDHHLC_03223	3.68e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
CIGDHHLC_03224	1.75e-95	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
CIGDHHLC_03225	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CIGDHHLC_03226	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
CIGDHHLC_03227	1.58e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
CIGDHHLC_03228	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CIGDHHLC_03229	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CIGDHHLC_03251	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
CIGDHHLC_03252	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
CIGDHHLC_03253	5.71e-121	-	-	-	M	-	-	-	FR47-like protein
CIGDHHLC_03254	9.14e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
CIGDHHLC_03255	1.68e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
CIGDHHLC_03256	6.53e-108	yuaE	-	-	S	-	-	-	DinB superfamily
CIGDHHLC_03257	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03258	1.12e-134	yuaD	-	-	-	-	-	-	-
CIGDHHLC_03259	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
CIGDHHLC_03260	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CIGDHHLC_03261	2.9e-122	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
CIGDHHLC_03262	5.83e-118	yuaB	-	-	-	-	-	-	-
CIGDHHLC_03263	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
CIGDHHLC_03264	1.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
CIGDHHLC_03265	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
CIGDHHLC_03266	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIGDHHLC_03267	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
CIGDHHLC_03268	5.39e-111	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
CIGDHHLC_03270	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CIGDHHLC_03271	1.73e-252	yubA	-	-	S	-	-	-	transporter activity
CIGDHHLC_03272	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
CIGDHHLC_03273	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
CIGDHHLC_03274	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
CIGDHHLC_03275	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
CIGDHHLC_03276	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
CIGDHHLC_03277	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
CIGDHHLC_03278	2.17e-19	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
CIGDHHLC_03279	2.61e-185	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
CIGDHHLC_03280	2.35e-115	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
CIGDHHLC_03281	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
CIGDHHLC_03282	2.02e-284	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
CIGDHHLC_03283	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
CIGDHHLC_03284	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
CIGDHHLC_03285	5e-48	-	-	-	-	-	-	-	-
CIGDHHLC_03286	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
CIGDHHLC_03287	7.23e-300	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
CIGDHHLC_03288	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
CIGDHHLC_03289	2.16e-48	-	-	-	-	-	-	-	-
CIGDHHLC_03290	5.01e-69	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
CIGDHHLC_03291	1.69e-231	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
CIGDHHLC_03292	2.75e-91	yugN	-	-	S	-	-	-	YugN-like family
CIGDHHLC_03294	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
CIGDHHLC_03295	1.2e-285	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
CIGDHHLC_03296	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
CIGDHHLC_03297	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
CIGDHHLC_03298	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
CIGDHHLC_03299	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
CIGDHHLC_03300	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03301	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
CIGDHHLC_03302	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
CIGDHHLC_03303	3.32e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CIGDHHLC_03304	4.32e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_03305	8.36e-90	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
CIGDHHLC_03306	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
CIGDHHLC_03308	4.61e-244	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
CIGDHHLC_03309	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
CIGDHHLC_03310	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_03311	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
CIGDHHLC_03312	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
CIGDHHLC_03313	1.88e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
CIGDHHLC_03314	9e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
CIGDHHLC_03315	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_03316	1.29e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CIGDHHLC_03317	1.15e-213	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CIGDHHLC_03318	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
CIGDHHLC_03319	1.42e-21	-	-	-	-	-	-	-	-
CIGDHHLC_03320	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CIGDHHLC_03321	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CIGDHHLC_03322	3.48e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CIGDHHLC_03323	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CIGDHHLC_03324	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CIGDHHLC_03325	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CIGDHHLC_03326	8.49e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
CIGDHHLC_03327	9.49e-84	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
CIGDHHLC_03328	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CIGDHHLC_03329	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_03331	3.33e-168	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
CIGDHHLC_03332	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
CIGDHHLC_03334	8.73e-09	yuzC	-	-	-	-	-	-	-
CIGDHHLC_03335	6.88e-297	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
CIGDHHLC_03336	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIGDHHLC_03337	3.82e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
CIGDHHLC_03338	8.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CIGDHHLC_03339	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
CIGDHHLC_03340	6.9e-41	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
CIGDHHLC_03341	1.35e-244	yueF	-	-	S	-	-	-	transporter activity
CIGDHHLC_03342	6.59e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
CIGDHHLC_03343	1.19e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
CIGDHHLC_03344	3.85e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
CIGDHHLC_03345	6.83e-168	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_03346	2.78e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
CIGDHHLC_03347	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
CIGDHHLC_03348	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CIGDHHLC_03349	1.93e-267	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
CIGDHHLC_03350	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
CIGDHHLC_03351	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
CIGDHHLC_03352	2.96e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
CIGDHHLC_03353	4.02e-262	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
CIGDHHLC_03354	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
CIGDHHLC_03355	2.02e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
CIGDHHLC_03356	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIGDHHLC_03357	2.59e-227	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
CIGDHHLC_03358	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
CIGDHHLC_03359	5.78e-288	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
CIGDHHLC_03360	5.83e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_03361	1.27e-212	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
CIGDHHLC_03362	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
CIGDHHLC_03363	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
CIGDHHLC_03364	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
CIGDHHLC_03365	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CIGDHHLC_03366	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
CIGDHHLC_03367	5.21e-148	yuiC	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_03368	1.97e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
CIGDHHLC_03369	1.39e-299	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CIGDHHLC_03370	1.92e-239	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
CIGDHHLC_03372	1.51e-233	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIGDHHLC_03373	1.36e-123	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
CIGDHHLC_03374	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
CIGDHHLC_03375	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CIGDHHLC_03376	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CIGDHHLC_03377	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03379	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
CIGDHHLC_03380	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CIGDHHLC_03381	5.44e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_03382	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
CIGDHHLC_03383	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
CIGDHHLC_03384	2.99e-220	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CIGDHHLC_03385	9.76e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CIGDHHLC_03386	6.79e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
CIGDHHLC_03387	2.57e-252	yutH	-	-	S	-	-	-	Spore coat protein
CIGDHHLC_03388	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
CIGDHHLC_03389	2.13e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CIGDHHLC_03390	1.61e-97	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
CIGDHHLC_03391	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_03392	1.34e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CIGDHHLC_03393	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CIGDHHLC_03394	1.08e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
CIGDHHLC_03395	3.49e-169	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
CIGDHHLC_03396	5.67e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
CIGDHHLC_03397	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CIGDHHLC_03398	7.59e-180	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CIGDHHLC_03399	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
CIGDHHLC_03400	1.07e-79	yunG	-	-	-	-	-	-	-
CIGDHHLC_03401	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
CIGDHHLC_03402	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
CIGDHHLC_03403	2.82e-298	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
CIGDHHLC_03404	4.37e-273	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
CIGDHHLC_03405	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
CIGDHHLC_03406	2.09e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
CIGDHHLC_03408	0.000154	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
CIGDHHLC_03409	1.7e-122	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
CIGDHHLC_03410	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
CIGDHHLC_03411	2.47e-187	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
CIGDHHLC_03412	4.18e-141	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
CIGDHHLC_03413	7.18e-234	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CIGDHHLC_03414	9.52e-303	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
CIGDHHLC_03415	4.82e-294	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
CIGDHHLC_03416	4.42e-216	bsn	-	-	L	-	-	-	Ribonuclease
CIGDHHLC_03417	2.83e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGDHHLC_03418	8.71e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
CIGDHHLC_03419	5.54e-208	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
CIGDHHLC_03420	4.53e-107	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
CIGDHHLC_03421	1.29e-89	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
CIGDHHLC_03422	2.05e-198	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIGDHHLC_03423	2.46e-308	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
CIGDHHLC_03424	9.11e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
CIGDHHLC_03425	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
CIGDHHLC_03426	2.63e-264	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
CIGDHHLC_03428	3.35e-56	-	-	-	-	-	-	-	-
CIGDHHLC_03429	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_03430	4.63e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_03431	2.06e-85	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIGDHHLC_03432	1.25e-56	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CIGDHHLC_03433	2.51e-13	-	-	-	-	-	-	-	-
CIGDHHLC_03435	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CIGDHHLC_03436	4.02e-109	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
CIGDHHLC_03437	8.72e-142	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
CIGDHHLC_03438	1.79e-74	-	-	-	S	-	-	-	Bacteriophage holin family
CIGDHHLC_03441	2.17e-238	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
CIGDHHLC_03442	0.0	-	-	-	-	-	-	-	-
CIGDHHLC_03443	1.22e-136	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
CIGDHHLC_03445	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
CIGDHHLC_03448	1.46e-33	-	-	-	-	-	-	-	-
CIGDHHLC_03450	8.3e-40	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
CIGDHHLC_03451	8.17e-38	-	-	-	S	-	-	-	Phage head-tail joining protein
CIGDHHLC_03453	5.45e-13	-	-	-	-	-	-	-	-
CIGDHHLC_03454	7.58e-162	-	-	-	S	-	-	-	capsid protein
CIGDHHLC_03455	1.32e-92	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
CIGDHHLC_03456	1.33e-216	-	-	-	S	-	-	-	portal protein
CIGDHHLC_03458	1.19e-179	terL	-	-	S	-	-	-	Terminase
CIGDHHLC_03459	3.93e-73	-	-	-	L	-	-	-	Terminase, small subunit
CIGDHHLC_03465	1.6e-94	-	-	-	L	-	-	-	Phage integrase family
CIGDHHLC_03466	9.58e-67	-	-	-	M	-	-	-	ArpU family transcriptional regulator
CIGDHHLC_03471	3.09e-63	-	-	-	S	-	-	-	dUTPase
CIGDHHLC_03477	2.78e-08	-	-	-	-	-	-	-	-
CIGDHHLC_03480	1.88e-09	-	-	-	-	-	-	-	-
CIGDHHLC_03482	2.01e-64	-	-	-	L	ko:K02315,ko:K11144	-	ko00000,ko03032	DNA replication protein
CIGDHHLC_03483	2.79e-87	-	-	-	L	-	-	-	dnaD_dom DnaD domain protein
CIGDHHLC_03485	4.59e-23	-	-	-	-	-	-	-	-
CIGDHHLC_03486	1.7e-08	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGDHHLC_03487	7.24e-60	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGDHHLC_03491	1.79e-149	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIGDHHLC_03492	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
CIGDHHLC_03493	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
CIGDHHLC_03494	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CIGDHHLC_03495	6.1e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
CIGDHHLC_03496	4.46e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CIGDHHLC_03497	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CIGDHHLC_03498	1.96e-187	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
CIGDHHLC_03499	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
CIGDHHLC_03500	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CIGDHHLC_03501	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
CIGDHHLC_03502	8.14e-73	yusE	-	-	CO	-	-	-	Thioredoxin
CIGDHHLC_03503	8.9e-96	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
CIGDHHLC_03504	2.11e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
CIGDHHLC_03505	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
CIGDHHLC_03506	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
CIGDHHLC_03507	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
CIGDHHLC_03508	3.15e-277	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
CIGDHHLC_03509	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
CIGDHHLC_03510	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
CIGDHHLC_03511	8.15e-210	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
CIGDHHLC_03512	2.23e-54	-	-	-	-	-	-	-	-
CIGDHHLC_03513	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
CIGDHHLC_03514	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
CIGDHHLC_03515	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
CIGDHHLC_03516	4.86e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
CIGDHHLC_03517	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_03518	5.68e-202	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
CIGDHHLC_03519	3.99e-53	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
CIGDHHLC_03520	8.74e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CIGDHHLC_03521	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
CIGDHHLC_03522	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
CIGDHHLC_03524	2.98e-14	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CIGDHHLC_03525	3.54e-95	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC superfamily ATP binding cassette transporter ABC protein
CIGDHHLC_03526	6.4e-09	-	-	-	J	-	-	-	O-methyltransferase
CIGDHHLC_03527	2.94e-17	-	-	-	EGP	-	-	-	Major Facilitator
CIGDHHLC_03529	3.05e-20	-	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
CIGDHHLC_03531	1.26e-18	-	-	-	-	-	-	-	-
CIGDHHLC_03532	5.75e-160	-	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CIGDHHLC_03533	2.71e-176	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_03534	8.76e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
CIGDHHLC_03536	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03537	2.17e-302	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CIGDHHLC_03538	6.4e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_03539	9.22e-317	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_03540	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03541	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CIGDHHLC_03542	1.06e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
CIGDHHLC_03543	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
CIGDHHLC_03544	7.95e-251	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
CIGDHHLC_03545	5.54e-234	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
CIGDHHLC_03546	8.64e-137	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CIGDHHLC_03547	3.34e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_03548	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
CIGDHHLC_03549	8.15e-172	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
CIGDHHLC_03550	2.85e-142	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
CIGDHHLC_03551	1.07e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
CIGDHHLC_03552	1.53e-286	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_03553	5.32e-129	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
CIGDHHLC_03554	5.43e-311	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
CIGDHHLC_03555	7.73e-236	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_03556	7.32e-219	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
CIGDHHLC_03557	2.89e-179	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_03558	3.79e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
CIGDHHLC_03559	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
CIGDHHLC_03560	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_03561	5.07e-32	-	-	-	-	-	-	-	-
CIGDHHLC_03562	1.12e-124	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
CIGDHHLC_03563	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
CIGDHHLC_03564	3.76e-291	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
CIGDHHLC_03565	2.84e-85	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
CIGDHHLC_03566	3.36e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
CIGDHHLC_03567	4.64e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_03568	3.44e-229	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
CIGDHHLC_03569	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CIGDHHLC_03570	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_03571	4.04e-235	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGDHHLC_03572	2.57e-224	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIGDHHLC_03574	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
CIGDHHLC_03575	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
CIGDHHLC_03576	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
CIGDHHLC_03577	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
CIGDHHLC_03578	2.97e-213	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
CIGDHHLC_03579	2.11e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
CIGDHHLC_03580	1.01e-152	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
CIGDHHLC_03581	6.19e-201	yvgN	-	-	S	-	-	-	reductase
CIGDHHLC_03582	9.32e-112	yvgO	-	-	-	-	-	-	-
CIGDHHLC_03583	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
CIGDHHLC_03584	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
CIGDHHLC_03585	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CIGDHHLC_03586	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CIGDHHLC_03588	6.7e-139	yvgT	-	-	S	-	-	-	membrane
CIGDHHLC_03589	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
CIGDHHLC_03590	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
CIGDHHLC_03591	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
CIGDHHLC_03593	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03594	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
CIGDHHLC_03595	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
CIGDHHLC_03596	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
CIGDHHLC_03597	1.99e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
CIGDHHLC_03598	2.92e-88	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CIGDHHLC_03599	7.68e-25	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CIGDHHLC_03600	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
CIGDHHLC_03601	1.94e-95	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
CIGDHHLC_03602	2.04e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
CIGDHHLC_03603	8.9e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGDHHLC_03604	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_03607	1.55e-235	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
CIGDHHLC_03610	6.14e-142	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
CIGDHHLC_03611	1.79e-74	-	-	-	S	-	-	-	Bacteriophage holin family
CIGDHHLC_03614	2.17e-238	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
CIGDHHLC_03615	0.0	-	-	-	-	-	-	-	-
CIGDHHLC_03616	1.62e-307	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
CIGDHHLC_03617	1.96e-141	-	-	-	S	-	-	-	Phage tail protein
CIGDHHLC_03618	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
CIGDHHLC_03619	4.09e-16	-	-	-	-	-	-	-	-
CIGDHHLC_03620	1.58e-36	-	-	-	-	-	-	-	-
CIGDHHLC_03621	9.75e-79	-	-	-	-	-	-	-	-
CIGDHHLC_03622	1.42e-40	-	-	-	-	-	-	-	-
CIGDHHLC_03623	1.54e-62	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
CIGDHHLC_03624	1.23e-32	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
CIGDHHLC_03625	1.23e-39	-	-	-	S	-	-	-	peptidoglycan catabolic process
CIGDHHLC_03626	8.02e-09	-	-	-	S	-	-	-	peptidoglycan catabolic process
CIGDHHLC_03627	3.43e-227	-	-	-	S	-	-	-	capsid protein
CIGDHHLC_03628	9.36e-135	-	-	-	S	-	-	-	peptidase activity
CIGDHHLC_03629	4.77e-273	-	-	-	S	-	-	-	Phage portal protein
CIGDHHLC_03630	2.58e-14	-	-	-	-	-	-	-	-
CIGDHHLC_03631	1.6e-276	-	-	-	S	-	-	-	Phage Terminase
CIGDHHLC_03632	1e-89	-	-	-	S	-	-	-	Phage terminase, small subunit
CIGDHHLC_03633	8.79e-12	-	-	-	-	-	-	-	-
CIGDHHLC_03634	1.9e-77	-	-	-	S	-	-	-	HNH endonuclease
CIGDHHLC_03635	0.000711	-	-	-	-	-	-	-	-
CIGDHHLC_03639	1.6e-94	-	-	-	L	-	-	-	Phage integrase family
CIGDHHLC_03640	9.58e-67	-	-	-	M	-	-	-	ArpU family transcriptional regulator
CIGDHHLC_03642	1.12e-07	-	-	-	S	-	-	-	YopX protein
CIGDHHLC_03644	1.76e-59	-	-	-	S	-	-	-	dUTPase
CIGDHHLC_03650	2.78e-08	-	-	-	-	-	-	-	-
CIGDHHLC_03653	1.76e-10	-	-	-	-	-	-	-	-
CIGDHHLC_03654	1.04e-21	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
CIGDHHLC_03655	1.81e-114	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
CIGDHHLC_03658	2.6e-09	-	-	-	T	ko:K21405	-	ko00000,ko03000	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
CIGDHHLC_03659	9.99e-59	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGDHHLC_03661	3.21e-78	-	-	-	-	-	-	-	-
CIGDHHLC_03662	4.26e-43	-	-	-	S	-	-	-	Phage integrase family
CIGDHHLC_03663	2.09e-81	-	-	-	S	-	-	-	Phage integrase family
CIGDHHLC_03665	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CIGDHHLC_03666	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CIGDHHLC_03667	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
CIGDHHLC_03668	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
CIGDHHLC_03669	2.84e-194	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
CIGDHHLC_03670	4.9e-48	yvzC	-	-	K	-	-	-	transcriptional
CIGDHHLC_03671	6.83e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
CIGDHHLC_03672	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
CIGDHHLC_03673	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
CIGDHHLC_03674	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
CIGDHHLC_03675	3.07e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
CIGDHHLC_03676	7.93e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CIGDHHLC_03677	1.27e-141	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
CIGDHHLC_03678	2.46e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CIGDHHLC_03679	3.28e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
CIGDHHLC_03680	1.13e-135	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
CIGDHHLC_03681	1.23e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CIGDHHLC_03682	4.63e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
CIGDHHLC_03683	1.08e-267	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CIGDHHLC_03684	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
CIGDHHLC_03685	1.32e-133	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
CIGDHHLC_03686	1.2e-144	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
CIGDHHLC_03687	2.66e-155	yvbI	-	-	M	-	-	-	Membrane
CIGDHHLC_03688	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
CIGDHHLC_03689	9.77e-106	yvbK	-	-	K	-	-	-	acetyltransferase
CIGDHHLC_03690	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CIGDHHLC_03691	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
CIGDHHLC_03692	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIGDHHLC_03693	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
CIGDHHLC_03694	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CIGDHHLC_03695	4.01e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CIGDHHLC_03696	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CIGDHHLC_03697	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
CIGDHHLC_03698	6.01e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIGDHHLC_03699	1.99e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03700	5.59e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
CIGDHHLC_03701	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
CIGDHHLC_03702	2.7e-187	-	-	-	S	-	-	-	Glycosyl hydrolase
CIGDHHLC_03703	6.88e-171	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CIGDHHLC_03704	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
CIGDHHLC_03705	7.47e-174	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CIGDHHLC_03706	3.88e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
CIGDHHLC_03707	4.23e-42	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
CIGDHHLC_03708	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CIGDHHLC_03709	1.09e-251	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_03710	8.31e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
CIGDHHLC_03711	1.1e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
CIGDHHLC_03712	8.47e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
CIGDHHLC_03713	1.89e-259	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
CIGDHHLC_03714	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
CIGDHHLC_03715	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
CIGDHHLC_03716	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
CIGDHHLC_03717	5.29e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
CIGDHHLC_03718	3.8e-291	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
CIGDHHLC_03719	6.96e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_03720	5.87e-147	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
CIGDHHLC_03721	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
CIGDHHLC_03722	7.32e-143	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
CIGDHHLC_03723	4.16e-118	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
CIGDHHLC_03724	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
CIGDHHLC_03725	3.07e-240	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
CIGDHHLC_03726	1.06e-278	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
CIGDHHLC_03727	3.33e-76	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
CIGDHHLC_03728	3.19e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CIGDHHLC_03729	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CIGDHHLC_03730	5.49e-240	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
CIGDHHLC_03731	1.83e-257	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
CIGDHHLC_03732	9.61e-246	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
CIGDHHLC_03733	7.25e-264	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
CIGDHHLC_03734	2.06e-277	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CIGDHHLC_03735	2.16e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
CIGDHHLC_03736	5.25e-280	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
CIGDHHLC_03737	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
CIGDHHLC_03738	2.28e-149	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
CIGDHHLC_03739	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
CIGDHHLC_03740	2.07e-97	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
CIGDHHLC_03741	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
CIGDHHLC_03743	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
CIGDHHLC_03744	1.18e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
CIGDHHLC_03745	1.27e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
CIGDHHLC_03746	2.3e-158	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
CIGDHHLC_03747	2.17e-224	pbpE	-	-	V	-	-	-	Beta-lactamase
CIGDHHLC_03748	3.77e-79	pbpE	-	-	V	-	-	-	Beta-lactamase
CIGDHHLC_03749	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
CIGDHHLC_03750	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
CIGDHHLC_03751	0.0	ybeC	-	-	E	-	-	-	amino acid
CIGDHHLC_03752	4.76e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03753	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
CIGDHHLC_03754	4.21e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
CIGDHHLC_03755	4.53e-95	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
CIGDHHLC_03757	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CIGDHHLC_03758	4.39e-146	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CIGDHHLC_03759	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
CIGDHHLC_03760	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
CIGDHHLC_03761	1.02e-199	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
CIGDHHLC_03762	2.29e-188	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
CIGDHHLC_03763	2.88e-307	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
CIGDHHLC_03764	3.44e-301	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
CIGDHHLC_03765	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
CIGDHHLC_03766	1.54e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03767	3.11e-136	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
CIGDHHLC_03768	3.2e-70	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
CIGDHHLC_03769	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
CIGDHHLC_03770	5.3e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
CIGDHHLC_03771	5.45e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIGDHHLC_03772	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
CIGDHHLC_03773	3.67e-180	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_03774	1.68e-252	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
CIGDHHLC_03775	3.69e-169	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_03776	7.42e-29	-	-	-	-	-	-	-	-
CIGDHHLC_03777	8.35e-185	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
CIGDHHLC_03778	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
CIGDHHLC_03779	1.04e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
CIGDHHLC_03780	5.52e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
CIGDHHLC_03781	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
CIGDHHLC_03782	9.76e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CIGDHHLC_03783	3.89e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CIGDHHLC_03784	1.08e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
CIGDHHLC_03785	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
CIGDHHLC_03786	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
CIGDHHLC_03788	0.0	-	-	-	-	-	-	-	-
CIGDHHLC_03789	3.7e-111	-	-	-	-	-	-	-	-
CIGDHHLC_03790	2.93e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
CIGDHHLC_03791	3.97e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CIGDHHLC_03792	4.61e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CIGDHHLC_03793	3.29e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CIGDHHLC_03794	2.02e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
CIGDHHLC_03795	1.81e-292	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CIGDHHLC_03796	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CIGDHHLC_03797	2.42e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CIGDHHLC_03798	4.31e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
CIGDHHLC_03799	5.68e-156	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
CIGDHHLC_03800	3.26e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_03801	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_03802	5.94e-118	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
CIGDHHLC_03803	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
CIGDHHLC_03804	4.16e-208	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
CIGDHHLC_03805	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CIGDHHLC_03806	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CIGDHHLC_03807	5.07e-281	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CIGDHHLC_03808	1.74e-165	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CIGDHHLC_03809	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
CIGDHHLC_03810	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
CIGDHHLC_03812	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03813	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
CIGDHHLC_03814	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
CIGDHHLC_03815	5.54e-219	yvlB	-	-	S	-	-	-	Putative adhesin
CIGDHHLC_03816	8.09e-65	yvlA	-	-	-	-	-	-	-
CIGDHHLC_03817	2.25e-45	yvkN	-	-	-	-	-	-	-
CIGDHHLC_03818	3.03e-147	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CIGDHHLC_03819	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CIGDHHLC_03820	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CIGDHHLC_03821	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_03822	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
CIGDHHLC_03823	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03824	3.03e-295	yvkA	-	-	P	-	-	-	-transporter
CIGDHHLC_03825	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CIGDHHLC_03826	2.69e-95	swrA	-	-	S	-	-	-	Swarming motility protein
CIGDHHLC_03827	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
CIGDHHLC_03828	4.83e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CIGDHHLC_03829	3.03e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
CIGDHHLC_03830	3.78e-74	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
CIGDHHLC_03831	1.31e-184	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
CIGDHHLC_03832	2.33e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CIGDHHLC_03833	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CIGDHHLC_03834	3.26e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_03835	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_03836	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CIGDHHLC_03837	2.46e-67	-	-	-	-	-	-	-	-
CIGDHHLC_03838	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
CIGDHHLC_03839	6.02e-90	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
CIGDHHLC_03840	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CIGDHHLC_03841	3.03e-74	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
CIGDHHLC_03842	4.34e-157	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CIGDHHLC_03843	1.05e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CIGDHHLC_03844	5.31e-61	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CIGDHHLC_03845	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03846	3.19e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CIGDHHLC_03847	1.99e-202	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
CIGDHHLC_03848	3.53e-178	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03849	8.52e-260	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CIGDHHLC_03850	7.75e-258	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
CIGDHHLC_03851	6.06e-61	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
CIGDHHLC_03852	1.05e-250	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
CIGDHHLC_03853	1.3e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
CIGDHHLC_03854	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIGDHHLC_03855	1.5e-257	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CIGDHHLC_03856	4.13e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CIGDHHLC_03857	2.4e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
CIGDHHLC_03858	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CIGDHHLC_03859	0.0	tagF2	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CIGDHHLC_03861	3.02e-171	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
CIGDHHLC_03862	2.7e-204	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CIGDHHLC_03863	1.07e-14	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
CIGDHHLC_03864	1.64e-204	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
CIGDHHLC_03865	2.43e-264	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CIGDHHLC_03867	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03868	2.13e-150	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CIGDHHLC_03869	1.82e-300	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CIGDHHLC_03870	4.98e-256	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
CIGDHHLC_03871	1.16e-301	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CIGDHHLC_03873	4.47e-315	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
CIGDHHLC_03874	4.16e-137	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
CIGDHHLC_03875	1.33e-174	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
CIGDHHLC_03876	7.15e-298	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
CIGDHHLC_03877	2.99e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
CIGDHHLC_03879	4.26e-100	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_03882	1.03e-50	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CIGDHHLC_03886	1.23e-151	-	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03887	1.94e-136	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
CIGDHHLC_03888	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
CIGDHHLC_03889	2.92e-162	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CIGDHHLC_03890	1.24e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_03891	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CIGDHHLC_03892	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
CIGDHHLC_03893	2.26e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
CIGDHHLC_03894	1.06e-95	yvyF	-	-	S	-	-	-	flagellar protein
CIGDHHLC_03895	8.72e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
CIGDHHLC_03896	7.06e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
CIGDHHLC_03897	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
CIGDHHLC_03898	7.66e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
CIGDHHLC_03899	6.92e-92	yviE	-	-	-	-	-	-	-
CIGDHHLC_03900	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_03901	2.29e-29	ywtC	-	-	-	-	-	-	-
CIGDHHLC_03902	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
CIGDHHLC_03903	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
CIGDHHLC_03904	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
CIGDHHLC_03905	1.18e-252	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
CIGDHHLC_03906	5.85e-225	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
CIGDHHLC_03907	8.06e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIGDHHLC_03908	3.12e-82	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CIGDHHLC_03909	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
CIGDHHLC_03910	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CIGDHHLC_03911	2.59e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
CIGDHHLC_03912	1.14e-118	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
CIGDHHLC_03913	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
CIGDHHLC_03914	1.24e-125	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
CIGDHHLC_03915	1.51e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
CIGDHHLC_03916	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
CIGDHHLC_03917	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
CIGDHHLC_03918	8.01e-263	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CIGDHHLC_03919	1.06e-162	ywrJ	-	-	-	-	-	-	-
CIGDHHLC_03920	3.02e-44	cotB	-	-	-	ko:K06325	-	ko00000	-
CIGDHHLC_03921	8.48e-265	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
CIGDHHLC_03922	1e-17	-	-	-	-	-	-	-	-
CIGDHHLC_03923	5.08e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CIGDHHLC_03924	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
CIGDHHLC_03925	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
CIGDHHLC_03926	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
CIGDHHLC_03927	6.44e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
CIGDHHLC_03928	1.01e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
CIGDHHLC_03930	1.44e-127	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
CIGDHHLC_03931	4.73e-209	-	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03932	2.88e-147	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
CIGDHHLC_03934	6.52e-35	-	-	-	S	ko:K11904,ko:K21493	ko03070,map03070	ko00000,ko00001,ko00002,ko01000,ko02044,ko02048	protein secretion by the type VII secretion system
CIGDHHLC_03935	4.93e-95	ywqJ	-	-	S	-	-	-	Pre-toxin TG
CIGDHHLC_03936	1.3e-23	-	-	-	-	-	-	-	-
CIGDHHLC_03937	2.5e-26	-	-	-	-	-	-	-	-
CIGDHHLC_03938	3.15e-265	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
CIGDHHLC_03939	8.84e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
CIGDHHLC_03941	9.48e-193	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
CIGDHHLC_03942	6.34e-311	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CIGDHHLC_03943	5.03e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
CIGDHHLC_03944	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
CIGDHHLC_03945	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
CIGDHHLC_03946	3.6e-25	-	-	-	-	-	-	-	-
CIGDHHLC_03947	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
CIGDHHLC_03948	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
CIGDHHLC_03949	3.57e-200	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
CIGDHHLC_03950	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
CIGDHHLC_03951	4.23e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
CIGDHHLC_03952	2.79e-40	ywpG	-	-	-	-	-	-	-
CIGDHHLC_03953	3.59e-88	ywpF	-	-	S	-	-	-	YwpF-like protein
CIGDHHLC_03954	3.81e-67	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CIGDHHLC_03955	4.66e-186	ywpD	-	-	T	-	-	-	Histidine kinase
CIGDHHLC_03956	7.66e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CIGDHHLC_03957	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CIGDHHLC_03958	1.5e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
CIGDHHLC_03959	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
CIGDHHLC_03960	9.37e-168	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
CIGDHHLC_03961	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
CIGDHHLC_03962	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
CIGDHHLC_03963	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
CIGDHHLC_03964	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_03965	3.25e-309	ywoF	-	-	P	-	-	-	Right handed beta helix region
CIGDHHLC_03966	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
CIGDHHLC_03967	8.92e-306	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
CIGDHHLC_03968	1.04e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
CIGDHHLC_03969	7.16e-101	-	-	-	-	-	-	-	-
CIGDHHLC_03970	3.76e-287	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
CIGDHHLC_03971	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
CIGDHHLC_03972	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
CIGDHHLC_03973	9.05e-93	ywnJ	-	-	S	-	-	-	VanZ like family
CIGDHHLC_03974	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
CIGDHHLC_03975	2.12e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
CIGDHHLC_03976	5.63e-17	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
CIGDHHLC_03977	6.7e-234	-	-	-	M	-	-	-	NeuB family
CIGDHHLC_03978	1.05e-91	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
CIGDHHLC_03979	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIGDHHLC_03980	1.28e-179	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
CIGDHHLC_03981	1.06e-78	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
CIGDHHLC_03982	1.42e-112	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
CIGDHHLC_03983	6.73e-19	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
CIGDHHLC_03984	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_03985	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CIGDHHLC_03986	1.12e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
CIGDHHLC_03987	6.75e-67	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
CIGDHHLC_03988	0.000282	-	-	-	E	ko:K11959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
CIGDHHLC_03989	2.15e-19	csbD	-	-	K	-	-	-	CsbD-like
CIGDHHLC_03990	8.55e-110	ywmF	-	-	S	-	-	-	Peptidase M50
CIGDHHLC_03991	6.22e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
CIGDHHLC_03992	1.08e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CIGDHHLC_03993	9.06e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CIGDHHLC_03995	3.4e-154	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
CIGDHHLC_03996	5.21e-155	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
CIGDHHLC_03997	3.05e-237	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
CIGDHHLC_03998	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIGDHHLC_03999	6.59e-172	ywmB	-	-	S	-	-	-	TATA-box binding
CIGDHHLC_04000	4.54e-45	ywzB	-	-	S	-	-	-	membrane
CIGDHHLC_04001	2.92e-113	ywmA	-	-	-	-	-	-	-
CIGDHHLC_04002	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
CIGDHHLC_04003	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CIGDHHLC_04004	1.28e-194	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CIGDHHLC_04005	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CIGDHHLC_04006	5.36e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIGDHHLC_04007	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CIGDHHLC_04008	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIGDHHLC_04009	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
CIGDHHLC_04010	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
CIGDHHLC_04011	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CIGDHHLC_04012	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CIGDHHLC_04013	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
CIGDHHLC_04014	9.57e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
CIGDHHLC_04015	9.54e-102	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIGDHHLC_04016	6.48e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
CIGDHHLC_04017	2.36e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CIGDHHLC_04018	2.55e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
CIGDHHLC_04019	2.29e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
CIGDHHLC_04020	9.69e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
CIGDHHLC_04022	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CIGDHHLC_04023	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CIGDHHLC_04024	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIGDHHLC_04025	2.45e-116	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
CIGDHHLC_04026	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
CIGDHHLC_04027	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
CIGDHHLC_04028	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
CIGDHHLC_04029	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
CIGDHHLC_04030	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CIGDHHLC_04031	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
CIGDHHLC_04032	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIGDHHLC_04034	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CIGDHHLC_04035	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
CIGDHHLC_04036	9.42e-66	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
CIGDHHLC_04037	2.28e-73	-	-	-	L	-	-	-	Transposase DDE domain
CIGDHHLC_04038	6.41e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
CIGDHHLC_04039	5.6e-173	-	-	-	L	-	-	-	Integrase core domain
CIGDHHLC_04040	7.55e-59	orfX1	-	-	L	-	-	-	Transposase
CIGDHHLC_04041	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CIGDHHLC_04042	8.03e-81	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CIGDHHLC_04043	5.77e-267	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
CIGDHHLC_04044	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
CIGDHHLC_04045	1.82e-275	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
CIGDHHLC_04046	3.3e-234	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
CIGDHHLC_04047	2.1e-13	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_04048	9.27e-107	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_04049	1.42e-109	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_04051	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
CIGDHHLC_04052	5.42e-95	ywiB	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_04053	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
CIGDHHLC_04054	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
CIGDHHLC_04056	5.02e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CIGDHHLC_04057	1.81e-292	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
CIGDHHLC_04058	3.84e-273	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
CIGDHHLC_04059	1.17e-315	-	-	-	L	-	-	-	Peptidase, M16
CIGDHHLC_04061	1.31e-303	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
CIGDHHLC_04062	1.57e-96	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
CIGDHHLC_04063	1.72e-156	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
CIGDHHLC_04064	3.28e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
CIGDHHLC_04066	2.76e-65	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
CIGDHHLC_04067	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
CIGDHHLC_04068	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CIGDHHLC_04069	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
CIGDHHLC_04070	2.1e-64	-	-	-	-	-	-	-	-
CIGDHHLC_04071	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
CIGDHHLC_04072	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
CIGDHHLC_04073	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
CIGDHHLC_04074	1.45e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_04075	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIGDHHLC_04077	1.54e-306	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
CIGDHHLC_04078	1.1e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_04079	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
CIGDHHLC_04080	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
CIGDHHLC_04081	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
CIGDHHLC_04082	6.58e-146	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
CIGDHHLC_04083	5.88e-200	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
CIGDHHLC_04084	4.16e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
CIGDHHLC_04085	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_04086	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
CIGDHHLC_04087	1.4e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
CIGDHHLC_04088	1.95e-175	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
CIGDHHLC_04089	3.03e-294	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
CIGDHHLC_04090	3.21e-267	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
CIGDHHLC_04091	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
CIGDHHLC_04092	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_04093	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
CIGDHHLC_04094	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
CIGDHHLC_04096	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_04097	3.81e-275	ywfA	-	-	EGP	-	-	-	-transporter
CIGDHHLC_04098	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
CIGDHHLC_04099	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
CIGDHHLC_04100	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
CIGDHHLC_04101	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
CIGDHHLC_04102	3.7e-101	-	-	-	-	-	-	-	-
CIGDHHLC_04103	1.52e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
CIGDHHLC_04104	2.34e-204	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CIGDHHLC_04105	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CIGDHHLC_04106	6.13e-177	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CIGDHHLC_04107	4.71e-239	spsG	-	-	M	-	-	-	Spore Coat
CIGDHHLC_04108	2.47e-164	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
CIGDHHLC_04109	7.93e-271	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
CIGDHHLC_04110	2.01e-208	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
CIGDHHLC_04111	3.06e-283	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
CIGDHHLC_04112	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
CIGDHHLC_04113	8.08e-187	spsA	-	-	M	-	-	-	Spore Coat
CIGDHHLC_04115	3.7e-106	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
CIGDHHLC_04116	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
CIGDHHLC_04117	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
CIGDHHLC_04118	1.26e-62	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
CIGDHHLC_04119	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CIGDHHLC_04120	2.32e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CIGDHHLC_04121	4.68e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
CIGDHHLC_04122	5.2e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CIGDHHLC_04123	6.19e-39	ywdA	-	-	-	-	-	-	-
CIGDHHLC_04124	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
CIGDHHLC_04125	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_04126	8e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
CIGDHHLC_04127	3.69e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
CIGDHHLC_04129	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
CIGDHHLC_04130	2.6e-233	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIGDHHLC_04131	1.9e-177	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
CIGDHHLC_04132	2.19e-174	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
CIGDHHLC_04134	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
CIGDHHLC_04135	1.3e-82	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
CIGDHHLC_04136	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
CIGDHHLC_04137	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CIGDHHLC_04138	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
CIGDHHLC_04139	5.11e-49	ydaS	-	-	S	-	-	-	membrane
CIGDHHLC_04140	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
CIGDHHLC_04141	5.34e-289	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CIGDHHLC_04142	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
CIGDHHLC_04143	1.98e-157	ywcC	-	-	K	-	-	-	transcriptional regulator
CIGDHHLC_04145	1.23e-63	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
CIGDHHLC_04146	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CIGDHHLC_04147	1.47e-143	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
CIGDHHLC_04148	2.54e-307	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
CIGDHHLC_04149	2.42e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
CIGDHHLC_04150	5.68e-314	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
CIGDHHLC_04151	3e-147	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CIGDHHLC_04152	5.39e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CIGDHHLC_04153	1.28e-201	ywbI	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_04154	4.47e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
CIGDHHLC_04155	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
CIGDHHLC_04156	7.14e-276	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
CIGDHHLC_04157	1.05e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
CIGDHHLC_04158	1.28e-276	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
CIGDHHLC_04159	8.1e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
CIGDHHLC_04160	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_04162	6.14e-162	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
CIGDHHLC_04163	1.81e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIGDHHLC_04164	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
CIGDHHLC_04165	4.43e-307	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_04166	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
CIGDHHLC_04167	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_04168	5.37e-216	gspA	-	-	M	-	-	-	General stress
CIGDHHLC_04169	3.49e-158	ywaF	-	-	S	-	-	-	Integral membrane protein
CIGDHHLC_04170	1.25e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_04171	1.28e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CIGDHHLC_04172	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
CIGDHHLC_04173	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
CIGDHHLC_04174	7.55e-59	orfX1	-	-	L	-	-	-	Transposase
CIGDHHLC_04175	5.6e-173	-	-	-	L	-	-	-	Integrase core domain
CIGDHHLC_04176	5.95e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
CIGDHHLC_04177	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIGDHHLC_04178	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
CIGDHHLC_04179	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIGDHHLC_04180	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CIGDHHLC_04181	1.5e-60	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_04182	2.19e-07	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_04183	3.56e-43	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_04184	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
CIGDHHLC_04185	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CIGDHHLC_04186	8.33e-68	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_04187	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIGDHHLC_04188	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
CIGDHHLC_04189	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
CIGDHHLC_04190	1.05e-26	yxzF	-	-	-	-	-	-	-
CIGDHHLC_04191	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
CIGDHHLC_04192	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
CIGDHHLC_04193	3.52e-274	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIGDHHLC_04194	1.14e-178	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CIGDHHLC_04195	3.33e-210	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_04196	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
CIGDHHLC_04197	1.63e-39	-	-	-	-	-	-	-	-
CIGDHHLC_04198	1.93e-62	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
CIGDHHLC_04199	2.6e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIGDHHLC_04200	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
CIGDHHLC_04201	3.73e-202	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CIGDHHLC_04202	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
CIGDHHLC_04203	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
CIGDHHLC_04204	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
CIGDHHLC_04205	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
CIGDHHLC_04206	1.09e-307	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
CIGDHHLC_04207	0.0	-	-	-	O	-	-	-	Peptidase family M48
CIGDHHLC_04209	1.77e-197	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
CIGDHHLC_04210	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGDHHLC_04211	7.85e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
CIGDHHLC_04212	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CIGDHHLC_04213	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CIGDHHLC_04215	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
CIGDHHLC_04216	2.11e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
CIGDHHLC_04217	3.81e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
CIGDHHLC_04218	1.76e-166	-	-	-	T	-	-	-	Signal transduction histidine kinase
CIGDHHLC_04219	8.24e-73	-	-	-	T	-	-	-	Signal transduction histidine kinase
CIGDHHLC_04220	2.69e-148	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
CIGDHHLC_04221	1.83e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
CIGDHHLC_04223	2.88e-111	yxjI	-	-	S	-	-	-	LURP-one-related
CIGDHHLC_04224	2.13e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
CIGDHHLC_04225	2.21e-275	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
CIGDHHLC_04226	1.67e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CIGDHHLC_04227	1.69e-150	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CIGDHHLC_04228	6.6e-168	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CIGDHHLC_04229	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
CIGDHHLC_04230	9.07e-197	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
CIGDHHLC_04231	3.47e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CIGDHHLC_04232	1.51e-91	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
CIGDHHLC_04233	2.28e-63	yxiS	-	-	-	-	-	-	-
CIGDHHLC_04234	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
CIGDHHLC_04235	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
CIGDHHLC_04236	7.21e-183	bglS	-	-	M	-	-	-	licheninase activity
CIGDHHLC_04237	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
CIGDHHLC_04238	7.23e-141	-	-	-	-	-	-	-	-
CIGDHHLC_04239	3.8e-292	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
CIGDHHLC_04240	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
CIGDHHLC_04241	3.52e-274	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
CIGDHHLC_04244	4.06e-58	yxiJ	-	-	S	-	-	-	YxiJ-like protein
CIGDHHLC_04247	1.86e-40	-	-	-	-	-	-	-	-
CIGDHHLC_04248	8.21e-50	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
CIGDHHLC_04249	3.42e-173	-	-	-	-	-	-	-	-
CIGDHHLC_04252	6.09e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2750)
CIGDHHLC_04253	9.7e-68	yxxG	-	-	-	-	-	-	-
CIGDHHLC_04254	4.67e-89	yxiG	-	-	-	-	-	-	-
CIGDHHLC_04255	4.48e-58	-	-	-	-	-	-	-	-
CIGDHHLC_04256	7.13e-100	-	-	-	-	-	-	-	-
CIGDHHLC_04257	8.9e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF4240)
CIGDHHLC_04258	5.06e-175	-	-	-	-	-	-	-	-
CIGDHHLC_04260	1.27e-69	-	-	-	-	-	-	-	-
CIGDHHLC_04261	6.47e-100	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
CIGDHHLC_04262	3.29e-19	yxiJ	-	-	S	-	-	-	YxiJ-like protein
CIGDHHLC_04263	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
CIGDHHLC_04264	5.69e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
CIGDHHLC_04265	1.36e-160	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGDHHLC_04266	4.54e-157	-	1.14.11.45	-	E	ko:K20418	-	ko00000,ko01000	2OG-Fe dioxygenase
CIGDHHLC_04267	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
CIGDHHLC_04268	8.86e-317	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CIGDHHLC_04269	1.56e-53	-	-	-	-	-	-	-	-
CIGDHHLC_04270	5.35e-102	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
CIGDHHLC_04271	0.0	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
CIGDHHLC_04272	1.33e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
CIGDHHLC_04273	5.38e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
CIGDHHLC_04274	0.0	-	-	-	L	-	-	-	HKD family nuclease
CIGDHHLC_04275	1.23e-78	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CIGDHHLC_04276	2.01e-193	-	-	-	L	-	-	-	Protein of unknown function (DUF2726)
CIGDHHLC_04277	1.49e-308	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
CIGDHHLC_04278	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CIGDHHLC_04279	2.24e-204	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
CIGDHHLC_04280	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
CIGDHHLC_04281	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CIGDHHLC_04282	1.18e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CIGDHHLC_04283	7.06e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CIGDHHLC_04284	8.39e-194	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
CIGDHHLC_04285	2.99e-249	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
CIGDHHLC_04286	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
CIGDHHLC_04287	4.78e-271	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
CIGDHHLC_04288	6.82e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_04289	3e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
CIGDHHLC_04290	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
CIGDHHLC_04291	6.03e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIGDHHLC_04292	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIGDHHLC_04293	4.03e-239	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
CIGDHHLC_04294	3.29e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
CIGDHHLC_04297	5.99e-41	yxeE	-	-	-	-	-	-	-
CIGDHHLC_04298	7.57e-28	yxeD	-	-	-	-	-	-	-
CIGDHHLC_04299	9.65e-91	-	-	-	-	-	-	-	-
CIGDHHLC_04300	1.55e-215	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIGDHHLC_04301	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
CIGDHHLC_04302	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
CIGDHHLC_04303	8.64e-178	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGDHHLC_04304	1.75e-227	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_04305	9.37e-159	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_04306	3.3e-203	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
CIGDHHLC_04307	2.29e-193	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
CIGDHHLC_04308	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
CIGDHHLC_04309	4.44e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
CIGDHHLC_04310	1.34e-294	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
CIGDHHLC_04311	4.99e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
CIGDHHLC_04312	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
CIGDHHLC_04313	1.75e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
CIGDHHLC_04314	2.43e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
CIGDHHLC_04315	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CIGDHHLC_04316	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
CIGDHHLC_04317	2.04e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
CIGDHHLC_04318	7.27e-55	-	-	-	-	-	-	-	-
CIGDHHLC_04320	2.23e-17	-	-	-	S	-	-	-	CGNR zinc finger
CIGDHHLC_04321	1.05e-101	-	-	-	T	-	-	-	HPP family
CIGDHHLC_04322	2.22e-38	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CIGDHHLC_04323	2.4e-233	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CIGDHHLC_04324	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
CIGDHHLC_04326	9.3e-23	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
CIGDHHLC_04327	2.01e-156	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
CIGDHHLC_04328	6.97e-264	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGDHHLC_04329	3.42e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CIGDHHLC_04330	2.54e-43	yxaI	-	-	S	-	-	-	membrane protein domain
CIGDHHLC_04331	7.97e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
CIGDHHLC_04332	1.35e-97	yxaI	-	-	S	-	-	-	membrane protein domain
CIGDHHLC_04333	1.46e-283	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
CIGDHHLC_04334	5.18e-251	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
CIGDHHLC_04335	1.12e-129	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
CIGDHHLC_04336	2.49e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CIGDHHLC_04337	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIGDHHLC_04338	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
CIGDHHLC_04339	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
CIGDHHLC_04340	7.3e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
CIGDHHLC_04341	2e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
CIGDHHLC_04342	1.27e-163	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
CIGDHHLC_04343	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
CIGDHHLC_04344	1.18e-294	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
CIGDHHLC_04345	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CIGDHHLC_04346	2.68e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
CIGDHHLC_04347	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
CIGDHHLC_04348	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CIGDHHLC_04349	4.15e-14	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CIGDHHLC_04350	1.95e-159	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
CIGDHHLC_04351	9.5e-153	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
CIGDHHLC_04352	8.4e-143	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIGDHHLC_04353	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
CIGDHHLC_04354	9.06e-47	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
CIGDHHLC_04355	1.66e-100	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
CIGDHHLC_04356	6.92e-17	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
CIGDHHLC_04357	4.78e-152	-	-	-	L	-	-	-	Bacterial dnaA protein
CIGDHHLC_04358	6.98e-279	-	-	-	L	-	-	-	Transposase
CIGDHHLC_04359	6.83e-45	-	-	-	-	-	-	-	-
CIGDHHLC_04360	0.0	-	-	-	V	-	-	-	Abi-like protein
CIGDHHLC_04361	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases
CIGDHHLC_04362	0.0	-	-	-	L	-	-	-	AAA ATPase domain
CIGDHHLC_04363	6.23e-148	-	-	-	S	-	-	-	HTH-like domain
CIGDHHLC_04364	1.07e-57	-	-	-	S	-	-	-	transposition, DNA-mediated
CIGDHHLC_04366	3.99e-53	-	-	-	-	-	-	-	-
CIGDHHLC_04367	2.46e-140	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
CIGDHHLC_04368	1.25e-14	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
CIGDHHLC_04369	1.59e-65	-	-	-	L	-	-	-	Transposase
CIGDHHLC_04370	3.91e-135	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
CIGDHHLC_04372	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CIGDHHLC_04374	1.64e-89	-	-	-	-	-	-	-	-
CIGDHHLC_04375	2.12e-296	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CIGDHHLC_04377	4.53e-41	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
CIGDHHLC_04378	2.71e-260	yycP	-	-	-	-	-	-	-
CIGDHHLC_04379	3.06e-156	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CIGDHHLC_04380	4.15e-108	yycN	-	-	K	-	-	-	Acetyltransferase
CIGDHHLC_04381	1.17e-18	-	-	-	S	-	-	-	aspartate phosphatase
CIGDHHLC_04382	2.06e-204	-	-	-	S	-	-	-	aspartate phosphatase
CIGDHHLC_04384	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
CIGDHHLC_04385	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
CIGDHHLC_04386	2.24e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
CIGDHHLC_04387	5.82e-20	-	-	-	-	-	-	-	-
CIGDHHLC_04388	4.85e-119	-	-	-	-	-	-	-	-
CIGDHHLC_04389	6.81e-19	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
CIGDHHLC_04390	3.95e-87	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
CIGDHHLC_04391	2.31e-54	sdpR	-	-	K	-	-	-	transcriptional
CIGDHHLC_04392	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
CIGDHHLC_04393	2.32e-279	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CIGDHHLC_04394	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
CIGDHHLC_04395	3.44e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_04396	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_04397	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGDHHLC_04398	2.07e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CIGDHHLC_04403	3.02e-313	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CIGDHHLC_04404	3.17e-97	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIGDHHLC_04405	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
CIGDHHLC_04406	2.87e-39	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
CIGDHHLC_04408	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
CIGDHHLC_04409	1.15e-280	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
CIGDHHLC_04410	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CIGDHHLC_04411	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
CIGDHHLC_04412	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
CIGDHHLC_04413	1.14e-34	yybS	-	-	S	-	-	-	membrane
CIGDHHLC_04414	4.15e-120	yybS	-	-	S	-	-	-	membrane
CIGDHHLC_04416	6.16e-20	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
CIGDHHLC_04417	1.71e-67	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
CIGDHHLC_04418	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_04419	2.83e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
CIGDHHLC_04420	3.19e-90	-	-	-	-	-	-	-	-
CIGDHHLC_04422	5.21e-70	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_04423	7.94e-200	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_04424	7.24e-141	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
CIGDHHLC_04425	2.05e-183	-	-	-	-	-	-	-	-
CIGDHHLC_04426	5.02e-87	-	-	-	S	-	-	-	SnoaL-like domain
CIGDHHLC_04427	6.02e-157	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
CIGDHHLC_04428	3.87e-132	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
CIGDHHLC_04429	4.41e-105	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
CIGDHHLC_04430	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
CIGDHHLC_04431	4.18e-90	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
CIGDHHLC_04432	1.55e-125	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
CIGDHHLC_04433	3.81e-87	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
CIGDHHLC_04434	2.28e-48	-	-	-	S	-	-	-	YjbR
CIGDHHLC_04435	1.67e-134	yyaP	-	-	H	-	-	-	RibD C-terminal domain
CIGDHHLC_04436	3.47e-108	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
CIGDHHLC_04437	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
CIGDHHLC_04438	2.1e-215	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CIGDHHLC_04439	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
CIGDHHLC_04440	3.01e-126	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
CIGDHHLC_04441	4.69e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIGDHHLC_04442	2.14e-154	ccpB	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_04443	2.65e-60	ccpB	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_04444	2.07e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
CIGDHHLC_04445	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CIGDHHLC_04446	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CIGDHHLC_04447	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
CIGDHHLC_04448	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CIGDHHLC_04449	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CIGDHHLC_04450	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
CIGDHHLC_04451	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
CIGDHHLC_04452	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
CIGDHHLC_04453	4.63e-72	-	-	-	L	-	-	-	transposase activity
CIGDHHLC_04454	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
CIGDHHLC_04455	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CIGDHHLC_04456	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
CIGDHHLC_04457	3.77e-97	-	-	-	S	-	-	-	Bacterial PH domain
CIGDHHLC_04458	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
CIGDHHLC_04459	8.33e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
CIGDHHLC_04460	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CIGDHHLC_04461	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CIGDHHLC_04462	4.32e-140	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
CIGDHHLC_04463	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIGDHHLC_04464	1.64e-70	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CIGDHHLC_04465	4.78e-228	-	-	-	L	-	-	-	Replication protein
CIGDHHLC_04466	1.1e-142	rapE	-	-	S	ko:K06363	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
CIGDHHLC_04469	2.58e-108	-	-	-	K	-	-	-	Transcriptional regulator
CIGDHHLC_04470	6.9e-302	pre	-	-	D	-	-	-	plasmid recombination enzyme
CIGDHHLC_04471	9.05e-77	-	-	-	V	-	-	-	Psort location Cytoplasmic, score
CIGDHHLC_04472	3.46e-80	-	-	-	K	-	-	-	Psort location Cytoplasmic, score